cancers Article Tyrosine Phosphoproteomics of Patient-Derived Xenografts Reveals Ephrin Type-B Receptor 4 Tyrosine Kinase as a Therapeutic Target in Pancreatic Cancer Santosh Renuse 1,2 , Vijay S. Madamsetty 3 , Dong-Gi Mun 1, Anil K. Madugundu 1,4,5, Smrita Singh 1,4,5 , Savita Udainiya 1,6, Kiran K. Mangalaparthi 1,4,7, Min-Sik Kim 8,9, Ren Liu 10, S. Ram Kumar 11, Valery Krasnoperov 12, Mark Truty 13, Rondell P. Graham 1, Parkash S. Gill 10, Debabrata Mukhopadhyay 3,* and Akhilesh Pandey 1,2,5,6,* 1 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA;
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[email protected] (R.P.G.) 2 Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA 3 Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, FL 32224, USA;
[email protected] 4 Institute of Bioinformatics, International Technology Park, Bangalore 560066, Karnataka, India 5 Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India Citation: Renuse, S.; Madamsetty, 6 Center for Molecular Medicine, NIMHANS, Bangalore 560027, Karnataka, India 7 V.S.; Mun, D.-G.; Madugundu, A.K.; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham University, Kollam 69025, Kerala, India 8 Singh, S.; Udainiya, S.; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Mangalaparthi, K.K.; Kim, M.-S.; Liu, Baltimore, MD 21205, USA;
[email protected] 9 Department of Biological Chemistry, Johns Hopkins University School of Medicine, R.; Kumar, S.R.; et al.