Livin (BIRC7) Rabbit Polyclonal Antibody – AP20649PU-N | Origene

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Livin (BIRC7) Rabbit Polyclonal Antibody – AP20649PU-N | Origene

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for AP20649PU-N Livin (BIRC7) Rabbit Polyclonal Antibody Product data: Product Type: Primary Antibodies Applications: WB Recommended Dilution: Western blot: 1/500 - 1/1000. Reactivity: Human Host: Rabbit Clonality: Polyclonal Specificity: This antibody detects endogenous levels of ML-IAP protein. Formulation: Phosphate buffered saline (PBS), pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide Concentration: 1.0 mg/ml Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE) Conjugation: Unconjugated Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Stability: Shelf life: one year from despatch. Predicted Protein Size: ~ 21 kDa Gene Name: Homo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 2 Database Link: Entrez Gene 79444 Human Q96CA5 This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 Livin (BIRC7) Rabbit Polyclonal Antibody – AP20649PU-N Background: Inhibitor of apoptosis proteins (IAPs) contain conserved, unique aminoterminal baculovirus IAP repeats (BIRs) and usually a C-terminal RING finger domain. Immunoprecipitation and Western blot analysis indicate that ML-IAP, also known as melanoma inhibitor of apoptosis protein, kidney inhibitor of apoptosis protein (KIAP), livin or BIRC7, binds to caspase-3, -7, and -9, but only inhibits caspase-9. Additionally, ML-IAP physically interacts with SMAC through its BIR domain with a very high affinity and this interaction is very specific. The gene which encodes ML-IAP maps to human chromosome 20q13.3. There is controversy regarding the localization of this protein and its involvement in apoptosis, but it has been suggested that ML-IAP may play a complex role in the regulation of apoptosis. Synonyms: KIAP, MLIAP, RNF50 Protein Families: Druggable Genome Product images: Western blot analysis of ML-IAP antibody (Cat.- No.: AP20649PU-N) in extracts from COLO cells. This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2.

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BIRC7 Sirna (Human)
For research purposes only, not for human use Product Data Sheet BIRC7 siRNA (Human) Catalog # Source Reactivity Applications CRJ2387 Synthetic H RNAi Description siRNA to inhibit BIRC7 expression using RNA interference Specificity BIRC7 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression. Form Lyophilized powder Gene Symbol BIRC7 Alternative Names KIAP; LIVIN; MLIAP; RNF50; Baculoviral IAP repeat-containing protein 7; Kidney inhibitor of apoptosis protein; KIAP; Livin; Melanoma inhibitor of apoptosis protein; ML-IAP; RING finger protein 50 Entrez Gene 79444 (Human) SwissProt Q96CA5 (Human) Purity > 97% Quality Control Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency. Components We offers pre-designed sets of 3 different target-specific siRNA oligo duplexes of human BIRC7 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2’-OMe) at no extra charge for increased stability and Application key: E- ELISA, WB- Western blot, IH- Immunohistochemistry,
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