The Royal Marsden NHS Foundation Trust – Medicines Formulary
Drug & Therapeutics Committee medicines & regimens approval list (2007 to present).
Medicine Clinical Unit DTC proposal date
20% Intralipid Trust wide January 2007
Abiraterone Urology unit September 2011
Gastro Intestinal January 2011 unit
Abraxane® Breast unit November 2014
Gynaecology unit September 2016
Pain, Palliative care Abstral® (sublingual fentanyl) and symptom January 2010 control The Royal Marsden NHS Foundation Trust – Medicines Formulary
Accelerated EC Breast Unit July 2019
Acetyl salicylate (aspirin) injection Critical Care Unit November 2012 (named patient)
Abemaciclib in combination Breast unit April 2019 with Fulvestrant
Afatanib Lung unit January 2014
Alectinib Lung unit June 2017 & June 2018
5-aminolaevulinic acid Dermatology unit December 2019 (Alemuz®) gel
Alemtuzumab Haemato-oncology July 2012 (named patient) unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Aloe-vera – skin care Radiotherapy unit May 2017
Gastro Intestinal Aflibercept March 2013 unit
Aprepitant Trust wide December 2011
Argatroban Trust wide April 2015
Atezolizumab Gynaecology unit January 2018
Atezolizumab in combination
with carboplatin & etoposide
Atezolizumab in combination with bevacizumab plus Lung unit March 2019 carboplatin and paclitaxel (ABCP) regimen The Royal Marsden NHS Foundation Trust – Medicines Formulary
Axitinib Renal unit October 2012
January 2011 Haemato-oncology Bendamustine unit December 2017
Bevacizumab Urology unit January 2008
Bevacizumab (monotherapy) Neuro-oncology unit January 2010
Haemato-oncology Bosutinib February 2015 unit
Botulinium toxin A Pain team December 2017
Buprenorphine (butrans® Paediatric unit January 2008 brand) The Royal Marsden NHS Foundation Trust – Medicines Formulary
Cabazitaxel Urology unit January 2011
Carboplatin (in addition to Breast unit September 2018 weekly paclitaxel) regimen
Haemato-oncology Carfilzomib March 2016 unit
Ceftazidime-avibactam Microbiology unit October 2018
Ceftozolone-Tazobactam Microbiology unit April 2017
Cetuximab & platinum regimen Head & Neck unit January 2011
Haemato-oncology Clofarabine February 2014 unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Clofarabine Paediatric unit January 2010
Gastro Intestinal Colesevalem January 2008 unit
Crizotinib Lung unit December 2012 & June 2018
Cyclophosphamide and Sarcoma unit July 2012 Prednisolone regimen
Skin & Melanoma Dabrafanib January 2014 unit
Dabrafenib and Trametinib Thyroid unit September 2019
Haemato-oncology Daratumumab July 2016 unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Haemato-oncology Dasatanib January 2008 unit
Haemato-oncology Defibrotide January 2009 unit
Degeralix Urology unit January 2011
Denosumab Breast unit November 2012
Dornase alfa Critical Care unit January 2013
Doxepin Pain team December 2017
Doxorubicin (myocet®) brand Gynaecology unit March 2012 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Duloxetine Pain Team November 2014
Durvalumab Lung unit April 2019
Edoxaban Trust wide December 2018
Enzalutamide Urology unit June 2013
Eribulin Breast unit December 2011
Gastro Intestinal Erlotinib January 2007 unit
Renal unit January 2009 Everolimus Paediatric unit January 2013 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Everolimus & Exemestane Breast unit November 2012 regimen
Surgical & Evicel surgical sealant Anaesthetics January 2009 departments
Fidaxomicin Microbiology unit July 2013
Gastro Intestinal Modified FOLFIRINOX regimen November 2018 unit
Formalin 5% aqueous solution Gastro Intestinal January 2008 (named patient). unit
Fosaprepitant Trust wide February 2012
January 2011 (oral) Fosfamycin Microbiology unit (named patient) April 2017 (IV formulation)
The Royal Marsden NHS Foundation Trust – Medicines Formulary
Gadoteric acid (dotarem®) Radiography January 2007 contrast medium department
Gefitinib Lung unit December 2009
Gastro Intestinal Gemcitabine January 2008 unit
Gemcitabine & nab paclitaxel GI unit December 2013 regimen
Haemato-oncology Gliteritinib June 2019 unit
Surgical & Human Fibrinogen Concentrate Anaesthetics January 2009 (Haemocomplettan). departments
Haemato-oncology Ibrutinib March 2015 unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Haemato-oncology Idelalasib July 2016 unit
Ifosfamide (continuous 14 day Sarcoma unit December 2009 infusion)
Haemato-oncology Imatanib September 2012 unit
Haemato-oncology Interferon gamma January 2009 unit
Invicorp Urology unit September 2016 (aviptadil/phentolamine).
Skin and Melanoma Ipilimumab September 2011 unit
Isavuconazole Microbiology unit May 2018 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Lapatanib Breast unit January 2008
Lapatanib in combination with Breast unit January 2011 an aromatase inhibitor
Haemato-oncology Lenalidomide July 2011 unit
Levosimendan Critical Care unit January 2009 (named patient)
Surgical & 1% lidocaine infusion Anaesthetics July 2019 (IV perioperative) departments
Lipegfilgrastim Trust wide April 2020
Liposomal Cytarabine- Haemato-oncology January 2019 Daunorubicin (Vyxeos) unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Liposomal Doxoribucin Sarcoma unit January 2008 (caelyx® brand)
Lomustine & Temozolamide Neuro-oncology unit July 2019
Lutetium-177-PSMA Urology unit June 2019
Methyl aminolevulinate 16% Dermatology unit May 2018 cream (Metvix®)
Pain, Palliative care Methyl naltrexone. and symptom January 2008 control
Methylphenidate Paediatric unit April 2019
Microbiology Micafungin November 2015 department
Gynaecology unit Mirena Coil (intrauterine The Royal Marsden NHS Foundation Trust – Medicines Formulary
device) September 2011
Mitotane Renal unit December 2009
Surgical & Monofer Anaesthetics October 2012 departments
Morphine sulphate in Intrasite Pain Team November 2019 gel
Nab-sirolimus Sarcoma March 2020
Pain, Palliative care Naloxegol and symptom April 2017 control
Nano-liposomal irinotecan G.I. unit April 2017 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Nelarabine Paediatric unit March 2012
Haemato-oncology Nelarabine February 2015 unit
Nilotinib Sarcoma unit January 2008
Nintedanib Lung unit March 2015
Niraparib Gynaecology unit November 2017
Skin & Melanoma September 2015 & February 2018 Nivolumab
GI Unit February 2018
Nivolumab Lung October 2015 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Critical Care unit & Octaplex January 2008 Theatres
Haemato-oncology Ofatumumab May 2012 unit
Gynae. Unit November 2015 & July 2018 Olaparib G.I. unit March 2020
Olaratumumab Sarcoma unit September 2017
Osimertinib Lung Unit May 2016
Urology unit December 2009 Paclitaxel Lung unit January 2009
Gastro Intestinal January 2011 unit Paclitaxel weekly regimen
Head & Neck unit September 2011
The Royal Marsden NHS Foundation Trust – Medicines Formulary
Palbociclib Breast unit February 2017
Gastro Intestinal Panatumumab February 2012 unit
Urology unit January 2011 Pazopanib Sarcoma unit September 2012
Pain, Palliative care Pecfent and symptom January 2012 intranasal fentanyl) control
Pemetrexed Lung unit January 2011
Skin & Melanoma October 2015
Haemato-oncology May 2016 unit Pembrolizumab
September 2016 Lung unit
October 2017 Urology unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Pembrolizumab in combination with Pemetrexed and Platinum Lung unit December 2018 regimen
Pertuzumab Breast unit May 2013
Phenzopyridine Urology unit September 2019
Pivecillinam Microbiology unit May 2017
Haemato-oncology Pixantrone February 2014 unit
Surgical & PlasmaLyte Anaesthetics October 2012 departments
Haemato-oncology Plerixafor January 2009 unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Haemato-oncology Pomalidomide September 2013 unit
Haemato-oncology Ponatanib February 2015 unit
Haemato-oncology Posaconazole January 2008 unit
Radium 223 Urology unit December 2013
Gastro Intestinal March 2015 unit Ramucirumab
Lung unit May 2016
Gastro Intestinal Rifaxamin February 2014 unit
Rituximab-bendamustine Haemato-oncology September 2012 regimen unit The Royal Marsden NHS Foundation Trust – Medicines Formulary
Sarcoma unit & GI Regorafenib December 2013 unit
Critical Care unit & Remifentanil January 2009 Theatres
Haemato-oncology Rituximab January 2008 unit
Haemato-oncology Rituximab January 2007 unit
Rucaparib Gynae. unit April 2019
Sirolimus Sarcoma unit January 2012
Gastro Intestinal January 2007 unit
Sorafenib January 2009 Urology unit
June 2019 Haemato-oncology The Royal Marsden NHS Foundation Trust – Medicines Formulary
unit
Sodium thiosulphate Paediatric unit November 2019
Urology unit January 2009
Sunitinib Gastro Intestinal January 2010 unit
Surgical & Tachosil Anaesthetics January 2008 departments
Pain, Palliative care Tapentadol and symptom September 2011 control
Temocillin Microbiology dept. June 2015
Temozolomide and Irinotecan Sarcoma unit January 2010 regimen The Royal Marsden NHS Foundation Trust – Medicines Formulary
Temsirolimus Urology unit January 2008
Testogel Urology unit January 2012
Gastro Intestinal Teysuno (S-1) September 2012 unit
Tolvaptan Trust wide January 2012
Topotecan (oral formulation) Lung unit January 2008
Trabectadin Sarcoma unit January 2007
Trabectadin and caelyx Gynaecology unit January 2010 regimen The Royal Marsden NHS Foundation Trust – Medicines Formulary
Trametanib Gynaecology unit December 2019
Pain, Palliative care Transdermal buprenorphine and symptom January 2008 control
Gastro Intestinal Trastuzumab (intravenous) January 2010 unit
Trastuzumab (subcutaneous) Breast unit December 2013
Trastuzumab emtansine Breast unit January 2014
Trometamol (THAM) Critical Care unit & February 2013 (named patient) Theatres
Vandetanib Head and Neck unit June 2012 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Skin and Melanoma Vemurafanib March 2012 unit
Haemato-oncology Venetoclax June 2018 unit
Haemato-oncology Venetoclax and low dose cytarabine June 2019 unit
Venetoclax and Hypomethalating Haemato-oncology January 2019 agent (Azacitidine or Decitabine) unit
Venetoclax in combination with low Haemato-oncology June 2019 dose cytarabine unit
Vinflunine Urology unit October 2012
Vinorelbine Lung unit May 2012 The Royal Marsden NHS Foundation Trust – Medicines Formulary
Vinorelbine Lung unit January 2009
Skin and Melanoma Vismodegib September 2013 unit
Vitamin A (in combination with Gastro Intestinal formalin 5%) January 2012 unit (named patient)