Scripta Scientifica Vox Studentium

Volume 1, suppl. 1, 2017

ISSN 2535-0471 (print) ISSN 2535-048X (online) MEDICAL UNIVERSITY “PROF. DR. PARASKEV STOYANOV” – VARNA

ABSTRACTS

OF

THE FIFTH

BLACK SEA SYMPOSIUM FOR YOUNG SCIENTISTS IN BIOMEDICINE !BSYSB"

April 6!9, 2017 Varna CONTENTS

CASE REPORTS Kalina Chavdarova, Viktor Urbanchich, Joana Andonova, Stayko Chavdarov, Georgi Guzgunov - AN INFANT WITH CONGENITAL HYPOTHYROIDISM AND A DISAPPEARING TUMOR ___ 15 Elizabet Miladinova, Aleksandra Gerasimova, Stela Petrova, Radina Dimitrova, Kiril Hristozov - MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A "SIPPLE SYNDROME# ______16 Greta Georgieva, Tina Traykova, Miroslav Stoykov, Albena Gencheva, Ivan Gonkov - DENTIGEROUS CYST: A CASE REPORT ______17 Veronika Zhelezova, Ivaylo Minev, Dimitar Dimitrov, Veselin Petrov, Niya Rasheva - WILSON’S DISEАSE IN CHILDHOOD! THE HEREDITARY FACTOR: A CASE REPORT ______18 Dinnar Yahya, Antoniya Atanasova, Monika Yaneva, Samuela Krasteva, Petya Petrova - PSOAS ABSCESS AS A COMPLICATION OF CROHN’S DISEASE % A CASE REPORT ______19 Ani Dzakova, Ersin Ismail, Deniz Hamidov, Snezhana Stancheva, Plamen Dimitrov - CASE REPORT OF PROPOFOL-INDUCED PULMONARY EDEMA ______20 Irini Karatsoli, Sezgin Syuli, Simona Nizorkova, Yavor Hinov, Chavdar Bachvarov - ENDOVASCULAR BRONCHIAL ARTERY EMBOLIZATION IN LIFE-THREATING HEMOPTYSIS. A CASE REPORT ______21 Yanitsa Dimitrova, Kristina Dimitrova, Hristina Pamukchiyska, Elena Harizanova, Diana Petkova - BIOLOGICAL THERAPY: A RISK FACTOR FOR DEVELOPING TUBERCULOSIS % A CASE REPORT ______22 Desislav Dobrev, Daniel Rachev, Miroslav Stoykov, Metodi Abadzhiev - TOOTH SUPPORTED OVERDENTURE UTILIZING PINLAY BALL ATTACHMENTS: A CASE REPORT ______23 Ivan Valkadinov, Djuliana Stoilova, Yavor Hinov, Simona Nizorkova, Chavdar Bachvarov - ENDOVASCULAR TREATMENT OF ACUTE ISCHEMIC STROKE ! AN ALTERNATIVE TECHNIQUE ______24 Lazar Kutin, Elisabeth Bossilkova, Georgi Popivanov, Ventzislav Mutafchiyski - SEVERE CARDIOMYOPATHY IMITATING ACUTE ABDOMEN ______25 Djuliana Stoilova, Evgeniya Kalevska, Ivan Valkadinov - CEREBRAL VENOUS THROMBOSIS ____ 26 Boryana Georgieva, Irina Ivanova, Milko Mirchev, Nikolay Georgiev - CARDIAC GASTRIC CANCER IN A PATIENT WITH A BLADDER NEOPLASM: CASE REPORT ______27 Dessyslava Nikolaeva, Dimo Nikolov, Stela Stanimirova, Veselin Aleksandrov, Merlin Mehmed - Efraim- EXTRAMEDULLARY PLASMACYTOMA OF THE SKULL BASE DEVELOPING INTO MULTIPLE MYELOMA: A CASE REPORT ______28 Dragostina Tsocheva, Katerina Marinova, Borislav Petrov, Rumen Nenkov, Radoslav Radev - GIANT PHYLLODES TUMOR-CASE REPORT ______29 Dimo Nikolov, Dessyslava Nikolaeva, Radi Lukanov, E. Ahmed, Valentin Ikonomov - INFLAMMATORY MYOFIBROBLASTIC TUMOUR OF THE KIDNEYS – CASE REPORT ______30 Mladena Radeva, Dimitar Grupchev - IRIDOCYCLECTOMY FOR CILIARY BODY MELANOMA ! UNIQUE APPROACH AND SURPRISING RESULT ______31 Mohamed Swamad, Yanislav Mitkov, Aygulya Akisheva, Dobromir Dimitrov, Chavdar Bachvarov - MULTIDISCIPLINARY APPROACH WITH SURGICAL ONCOPLASTY OF A 46 YO WOMAN WITH BREAST CANCER ______32 Merilin Ivanova, Jovana Kitanovska, Kalina Naydenova, Tatyana Betova, Paulina Milanova - WARTHIN’S TUMOR ! CASE AND REVIEW ______33 Blagovest Belchev, Konstantin Ganchev, Yosif Gerchev, Preslav Penev - HOFFA FRACTURE IN CHILDHOOD ______34 Roksana Tsvetanova, Zhenya Marinova, Tsvetan Popov, Yavor Enchev, Bogomil Iliev - COMBINED AUTOGENOUS AND ALLOPLASTIC CRANIOPLASTY IN A 15!YEAR!OLD TRAUMA PATIENT ! A CASE REPORT ______35 Dragomir Dragomirov, Meriyan Radeva, Natalia Stomatova , Rostislav Manev - Osteomyelitis ______36 Liliya Raeva, Boris Botev, Paola Kulicheva, Veselin Boyadzhiev, Lachezar Marinov - A CASE REPORT OF A CHILD WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS - A RARE BUT POTENTIALLY DANGEROUS DISEASE ______37 Violeta Dimitrova, Joana Andonova, Viktor Urbanchich, Vesela Zlateva, Maria Dimova - INFECTIVE ENDOCARDITIS IN INTRAVENOUS DRUG ABUSE ! A CLINICAL CASE ______38 Alexandar Byankov, Teodor Tsanev, Vasil Ivanov - RARE CASE OF A BLADDER CANCER IN AN 18!YEAR!OLD MALE PATIENT ______39 Liliya Ilieva, Mira Siderova, Savi Shishkov, Kiril Hristozov - CASE OF EUGLYCEMIC KETOACIDOSIS INDUCED BY SGLT2 INHIBITORS "SODIUM!GLUCOSE COTRANSPORTER 2# IN A DIABETIC PATIENT ______40 Abdul Shah, Valentina Dimova, Bilal Hejazi - DIFFICULT TREATMENT OF RECURRENT HAEMOPTYSIS IN POLYMORBID LUNGS % A CASE STUDY ______41 Miroslav Stoykov, Nina Nyagulova, Trayan Marinov, Maya Doychinova - AN IRRIGATION PROTOCOL USED FOR THE DEVITALISATION PROCESS OF A RIGHT MANDIBULAR CENTRAL INCISOR WITH A MODERATE ABRASION ! A CASE REPORT ______42 Diyana Kyuchukova, Simona Nikolaeva, Dilyana Tonkova, Cvetomir Yankov, Branimir Kanazirev - TAVI!PROCEDURE: A BRAND NEW START FOR A PATIENT WITH CLASS 3 NYHA HEART FAILURE ______43 Stefan Stefanov, Mustafa Dzhambazov, Dragomir Ivanov, Gergana Trifonova - DENTAL TRAUMA IN CHILDHOOD. REATTACHING A TOOTH FRAGMENT OF ANTERIOR FRACTURED TEETH ! CASE REPORT ______44 Tsvetan Popov, Daniel Zhelev, Zhenya Marinova, Roksana Tsvetanova, Ilina Micheva - CASE OF A STAGE IIIB HODGKIN’S LYMPHOMA PATIENT TREATED WITH BRENTUXIMAB ! MODERN CONCEPTS FOR IMMUNOTHERAPY ______45 Ahmed Ahmed, Nalyan Aliadinova, Borislav Todorov, Figen Mustafa, Margarita Trifonova - A CASE REPORT OF METASTATIC BREAST CANCER MANAGED WITH HORMONE THERAPY ______46 Yavor Kyumyurdzhiyski, Kaloyan Dobrev, Sibel Yuzeirova, Kolyo Karahristov, Valentina Dimitrova - RESPIRATORY INFECTIONS IN IMMUNOCOMPROMISED PATIENTS ______47 Aizaz Tariq, Georgi Davidov, Lilyana Petkova, Nikolay Sapundzhiev - CARCINOMA OF THE NASAL VESTIBULE ______48 Velina Kerekovska, Evelina Zlatanova - CLINICAL SIGNIFICANCE OF ELEVATED MACROPROLACTIN LEVELS IN PATIENTS WITH HYPERPROLACTINEMIA. CASE REPORT ______49 Veneta Yakimova, Maria Dimova, Krasimira Nenova - INSULINOMA______50 Desislava Nalbantova, Yasen Petrov, Ivona Zhekova, Simona Mileva, Tsvetana Yordanova - PNEUMOCYSTIS CARINII PNEUMONIA IN IMMUNOSUPPRESSED PATIENTS ______51 Desislava Nalbantova, Yasen Petrov, Ivona Zhekova, Simona Mileva, Tsvetana Yordanova - PYODERMA GANGRENOSUM % A FEASIBLE OPTION IN THE DIFFERENTIAL DIAGNOSIS OF SOFT TISSUE GANGRENE IN DIABETIC PATIENTS? ______52 Kalina Naydenova, Hristo Milev, Katya Todorova, Beatrice Pancheva, Nadya Docheva - PRIMARY EMPTY SELLA SYNDROME: AN UNUSUAL PRESENTATION OF PANHYPOPITUITARISM __ 53 Maneesha De Silva, Simona Angel , Kremen Tsvetkov, Emil Kovachev, Atanas Alexandrov - PLACENTA ACCRETA % A CASE REPORT ______54 Doychin Nikolov, Boryana Georgieva, Deyan Anakievski, Rostislav Marinov, Inna Gocheva, Viktor Nikolov - EARLY DISTRIBUTION OF SQUAMOUS PENILE CARCINOMA ______55 Joana Andonova, Violeta Dimitrova, Kalina Chavdarova, Maria Dimova, Vesela Zlateva - ADULT!ONSET STILL’S DISEASE ! A CLINICAL CASE ______56 Vasil Kitanov, Pamela Georgieva, Velichko Penchev, Orlin Asenov - DILEMMAS IN THE CARDIO! VASCULAR TREATMENT APPROACH. ANTICOAGULANT, ANTIPLATELET DRUG OR A COMBINATION? ______57 Mariya Levkova, Dimitrina Konstantinova, Tanya Kadiyska, Ivan Donev - INDIVIDUALIZED HORMONAL THERAPY IN PATIENTS WITH BREAST CANCER ______58 Teresa Buitrago García, Niarah Ahmad, Maria Dimova, Branimir Kanazirev - LEFT VENTRICULAR NON!COMPACTION CARDIOMYOPATHY ______59 Veselin Petrov, Veselin Petrov, Desislava Ivanova - COMPLICATION AFTER CARDIAC CATHETERIZATION IN A PATIENT WITH IHD ______60 Hristo Draganov, Kristina Dimitrova, Hristina Pamukchiyska, Elena Harizanova, Diana Petkova - LUNG TRANSPLANTATION OF A PATIENT WITH PULMONARY HYPERTENSION ______61 Rene-Alexander Starick, Laura Verna Fierro, Dilyana Tonkova, Stanislava Ivanova, Dobrin Kalchev - SUCCESFUL TREATMENT OF A BIDIRECTIONAL SHUNT - A CASE REPORT ______62 Viktor Urbanchich, Kalina Chavdarova, Violeta Dimitrova, Stayko Chavdarov, Georgi Guzgunov - AN INFANT WITH SPONTANEOUS TUMOR REGRESSION ______63 Johanna Loehr, Faidra Marazak, Mara Genovefa Marazak - RH INCOMPATIBILITY IN EARLY MEDICAL ABORTION, A MISOPROSTOL CASE REPORT ______64 Simona Panteleymonova, Elizabet Miladinva, Aleksandra Gerasimova, Tatyana Cvetkova, Kalina Stoyanova - TOXOCAROSIS "LARVA MIGRANS VISCERALIS# IN ADULT PATIENTS ___ 65

Catherina Shirokova, Savi Shishkov, Velina Kerekovska, Mila Boyadzhieva, Kiril Hristozov - A CASE OF CONGENITAL HYPOPITUITARISM ______66 Zekie Kasimova, Hristo Popov, Mariya Tsaneva - MIXED EPITHELIAL AND STROMAL TUMOR OF THE KIDNEY: A CASE REPORT ______67 Desislava Ivanova, Paolina Kamenova, Merlin Mehmed - CHRONIC MYELOMONOCYTIC LEUKEMIA "CMML#: A CASE REPORT ______68 Gabriela Kirisheva, Anton Tonev, Alexander Zlatarov, Nikola Kolev, Valentin Ignatov, Georgi Ivanov - CASE VARIATION OF SAINT’S TRIAD ______69 Ralica Ruseva, Anton Tonev, Alexander Zlatarov, Mehmed Hadzhiveli, Georgi Ivanov, Boris Andonov, Georgi Valentinov, Nikola Kolev, Valentin Ignatov, Krasimir Ivanov - RETROPERITONEAL HEMATOMA % A CASE REPORT ______70 Samuil Marinov, Anton Tonev, Alexander Zlatarov, Mehmed Hadzhiveli, Georgi Ivanov, Boris Andonov, Georgi Valentinov, Nikola Kolev, Valentin Ignatov, Krasimir Ivanov - MINIMALLY INVASIVE MANAGEMENT OF GIANT ESOPHAGEAL POLYP % A CASE REPORT ______71

ORIGINAL RESEARCH Petar Valchanov - 3D MODELING IN MEDICINE ! FROM DIGITAL TOMOGRAPHY TO A 3D MODEL ______72 Ivaylo Zhechev, Boyana Vasileva, Kristiyana Kolewa, Georgi Gaidarov, Desislava Videva - EPILEPSY IN CHILDHOOD % REVIEW OF THE LITERATURE ______73 Maya Nikova, Burdju Cicek, Radost Dimitrova, Yordan Slavov, Berkehan Koroglu - RESTORATION OF SENSATION USING HIGH!TECH PROSTHESES ! OVERVIEW ______74 Daniel Zhafal, Metodi Metodiev, Yoneli Netsova, Trifon Chervenkov - TRANSGENERATIONAL EPIGENETIC INHERITANCE: DOES IT EXIST? ______75 Boyana Vasileva, Georgi Gaidarov, Lili Goguleva, Desislava Videva, Kristiyana Kolewa - EMOTIONAL SELF!CONFIDENCE OF MEDICAL STUDENTS IN BULGARIA ______76 Lili Goguleva, Boyana Vasileva, Desislava Videva, Georgi Gaidarov, Irena Kostova - PSYCHO!EMOTIONAL DIFFICULTIES FOR PARENTS WITH THEIR FIRST CHILD ______77 Boris Enikov, Irini Karatsoli, Veronika Markova, Bogomil Iliev, Yavor Enchev - BURR HOLE ENDOSCOPE!ASSISTED EVACUATION OF CEREBELLAR HEMATOMAS "ICH# ______78 Radost Dimitrova, Burdju Cicek, Yordan Slavov, Berkehan Koroglu, Georgi Shopov - OVERVIEW OF VISUAL PROSTHESES ______79 Niarah Ahmad, Dominic Fazel, Teresa Buitrago Garcia, Foteini Tsipou, Veselin Boyadhzhiev - TO WHAT EXTENT DO EXTERNAL FACTORS CONTRIBUTE TO THE DEVELOPMENT OF ALLERGIES? ______80 Vasilena Kuzmanova, Atanas Kuzmanov, Stefka Valcheva-Kuzmanova - EXPERIMENTAL RAT MODELS OF PERIODONTITIS % A REVIEW ______81 Slavena Georgieva, Tsvetelina Borisova-Papancheva, Georgi Papanchev - SURGICAL VS NON! SURGICAL RETREATMENT OF ENDODONTIC CASES % FACTORS, INFLUENCING THE RETREATMENT CHOICE ______82 Ralitsa Yotsova, Dimitar Dochev, Ivelina Hristova, Panayotis Marinov, Yulia Tsulos - COMPARATIVE STUDY OF SINUS LIFT TECHNIQUES % BIOLOGICAL ASPECTS AND OUTCOMES ______83 Daniel Rachev, Desislav Dobrev, Borislava Toncheva, Rossen Kolarov - BISPHOSPHONATE!RELATED OSTEONECROSIS OF THE JAW ______84 Radina Ivanova, Krasimir Todorov, Georgi Ivanov, Milena Stoyanova - KABUKI SYNDROME _____ 85 Metodi Metodiev, Yoneli Netsova, Daniel Zhafal, Trifon Chervenkov - THE EXTENDED PHENOTYPE ______86 Boryana Atanasova, Aleksandra Dzhepkova, Marina Atanasova, Peter Ivanov, Regina Komsa-Penkova - MANAGEMENT OF REPRODUCTIVE HEALTH CONTROL. PAI!1, MTHFR MUTATION AND ANOVULATION ______87 Elena Harizanova, Desislava Marinova, Stoyan Pavlov, Doychin Angelov - QUANTIFICATION OF "RE#MYELINATION VIA LUXOL FAST BLUE STAINING IN THE INJURED SPINAL CORD OF ADULT RATS: EFFECTS OF WHOLE BODY VIBRATION ______88 Sofia Nikolova, Georgi Georgiev - ECHOCARDIOGRAPHIC ASSESSMENT OF PULMONARY EMBOLISM ! MCCONNELL’S SIGN ______89 Isil Uyanik, Elis Ismail - ULTRASOUND IN GYNAECOLOGICAL EMERGENCIES ______90 Ivaylo Minev, Veronika Zhelezova, Dimitar Dimitrov, Veselin Petrov, Ivona Kocheva - JUST UNIC. "JACK!UP SHOULDER PROSTHESIS FOR TRAUMA INDICATIONS# ______91 Dimitar Dimitrov, Valentin Dimitrov, Ivaylo Minev, Veronika Zhelezova, Dimitar Raikov - ORIF OF INTRAARTICULAR FRACTURES OF DISTAL HUMERUS WITH LCP BIPLANAR PLATING ______92 Aleksandra Gerasimova, Rumen Hristov, Petar Stamov, Galin Hristov, Sergei Glinkov - T!TUBE ENTEROSTOMY! A METHOD OF TREATMENT FOR INTESTINAL PERFORATION IN NEWBORNS WITH LOW AND EXTREMELY LOW WEIGHT ______93 Constantinos Voniatis, Daniella Fehér, Kristóf Molnár, Gyorgy Weber, Angéla Jedlovszky-Hajdú - TISSUE!ENGINEERED POLY"VINYL ALCOHOL# MESH PROSPECTS IN ABDOMINAL HERNIA TREATMENT ______94 Nellia Gwasunda, Rafal Al-Rabaey, Vasil Bozhkov, Rosen Madjov - ACUTE APPENDICITIS IN OLDER PATIENTS ______95 Ani Raynova, Simona Panteleymonova, Plamen Panayotov - ENDOVENTRICULAR CIRCULAR PATCH PLASTY FOR LEFT VENTRICULAR RECONSTRUCTION ______96 Dimana Mitsova, Aleksandra Stefanova, Elena Stoyanova, Plamen Angelov, Anton Dinkov - MALIGNANT HYPERTHERMIA % THE HIDDEN DANGER ______97 Burdju Cicek, Ishil Uyanik, Radost Dimitrova, Georgi Shopov, Berkehan Koroglu - OVERVIEW OF FOCUSED ULTRASOUND SURGERY ______98 Konstantin Ganchev, Blagovest Belchev, Desislava Simeonova, Dennis Veliev, Preslav Penev - ADAMS PROCEDURE % A METHOD OF REPAIR FOR POST!TRAUMATIC DRUJ INSTABILITY ______99 Krasen Tonev, Evgeni Grigorov, Konstantin Kalaidjiev - PHARMACOVIGILANCE AND ENSURING DRUG SAFETY ______100 Stela Petrova, Dimitar Koemdzhiev, Petko Iliev, Dimo Nikolov, Kalina Stoyanova - COMPARISON BETWEEN THREE LABORATORY METHODS FOR THE DIAGNOSIS OF CRYPTOSPORIDIUM 101 Dimitar Trizlov, Iliyaz Hadzhiev, Aleksandar Yordanov, Valeriy Yordanov - HER!2/NEU ! MOLECULAR STRUCTURE AND STATUS. ANTIBODY ! TARGETED THERAPY WITH PERTUZUMAB, TRASTUZUMAB AND DOCETAXEL AND THE IMPACT ON OVERALL SURVIVAL "OS# AND PROGRESSION!FREE SURVIVAL "PFS# IN PATIENTS WITH METASTATIC BREAST CANCER ______102 Zhenya Marinova, Roksana Tsvetanova, Elena Ivanova, Tsvetan Popov, Antoniya Kisheva - ASSESSMENT OF RIGHT!TO!LEFT SHUNTS USING CONTRAST TRANSCRANIAL DOPPLER ULTRASOUND % ADVANTAGES AND RELIABILITY OF THE METHOD ______103 Ivelina Hristova, Slavena Georgieva, Ralitsa Yotsova, Konstantina Velikova, Sirma Angelova - DENTAL TRAUMA. DECORONATION TECHNIQUE AS A SUCCESSFUL METHOD IN THE TREATMENT OF ANKYLOSIS ______104 Mustafa Djambazov, Dragomir Ivanov, Stefan Stefanov, Tsonka Dimitrova - ANALYSIS OF THE RISK OF DISTRIBUTION AND PREVENTION OF SEXUALLY TRANSMITTED DISEASES AND UNWANTED PREGNANCY AMONG STUDENTS FROM 9 TH TO 12 TH GRADE OF PROFESSIONAL SCHOOL OF NATURAL SCIENCES % “ACAD. N. OBRESHKOV” % RAZGRAD ______105 Maria Dzhinova, Vasil Yordanov, Siyana Gradanska, Milena Georgieva, Radosveta Andreeva - COOPERATION BETWEEN SPECIALISTS FOR PREVENTION OF EARLY CHILDHOOD CARIES ______106 Galini Kalavrytinou, Rosa Marand, Christiana Madjova - LITERATURE REVIEW BASED ON THE CONTRAINDICATIONS OF HYALURONIC ACID PERIORALLY ______107 Michael Enchev, Gergana Georgieva, Radost Vasileva - PHOTOGRAPHIC IMAGE REQUIREMENTS IN CONTEMPORARY DENTAL MEDICINE ______108 Ersin Ismail, Ani Dzakova, Deniz Hamidov, Meriyan Radeva, Plamen Dimitrov - SLEEP AND HEALTH – TENDENCIES, REASONS AND RISKS OF SLEEP DEPRIVATION ______109 Desislava Dokova, Ralitsa Toneva, Daniel Rachev, Desislav Dobrev, Georgi Georgiev - STATISTICAL ANALYSIS OF ORAL HYGIENE HABITS AND ORAL CANCER AWARENESS ___110 Martin Krustev, Silvia Filkova, Monika Popova, Luiza Hadzhieva - THE REFLECTION OF EXERCISE ON THE NEW GENERATION ______111 Jovana Kitanovska, Merilin Ivanova, Paulina Milanova, Sabie Korenarska, Galya Stavreva - ARTEMISIA ANNUA! A PLANT WITH A GREAT FUTURE ______112 Tsvetelina Stefanova, Syana Dimova, Nina Arhangelova, Yordanka Eneva - CONCENTRATION OF NATURAL RADIONUCLIDES IN CALENDULA OFFICINALIS L. FLOWERS ______113 Vladislav Stoychev, Mariya Chingalova, Vladislav Velikov, Dimitar Dimitrov, Rositsa Chamova - CURCUMIN ! PREVENTION AND THERAPY OF INFLAMMATORY DISEASES ______114 Nefize Ilyaz , Mery Koleva , Stefka Valcheva-Kuzmanova , Miroslav Eftimov - DRUG-INDUCED XEROSTOMIA AND ITS POTENTIAL TREATMENT ______115 Viktoria Tomova , Ivan Pavlov , Nadezhda Ivanova - EVALUATION OF THE EFFECTIVENESS AND MECHANISM OF ACTION OF HYPERICUM PERFORATUM IN THE TREATMENT OF DEPRESSIVE DISORDERS ______116 Georgi Ivanov , Gergana Angelova , Boyan Balev - MEDIAL TIBIAL STRESS SYNDROME ! IMAGING AND DIFFERENTIAL DIAGNOSIS ______117 Georgii Danylenko , Tatiana Merkulova , Natalia Romanova - IMPLEMENTATION OF STATE POLICY FOR PROTECTION OF CHILDREN’S HEALTH IN UKRAINIAN SCHOOLS ______118 Apostolos Pavlos Petridis , Daniela Pechlivanova, Kiril Petrov, Alexander Stoynev - BEHAVIORAL CHARACTERISTICS OF NORMOTENSIVE WISTAR AND SPONTANEOUSLY HYPERTENSIVE RATS WITH AN EXPERIMENTAL MODEL OF DIABETES MELLITUS TYPE 2 ______119 Victoria Tencheva, Mihaela Zaharieva, Jordan Kozhuharov, Pamela Dragieva, Irina Stoyanova - DOES GHRELIN AFFECT MEMORY? ______120 Pamela Dragieva , Mihaela Zaharieva , Krasimir Markov , Jordan Kozhuharov , Miglena Todorova - DOES A KETOGENIC DIET INFLUENCE PATIENTS WITH ALZHEIMER’S DISEASE? ______121 Vanesa Dodova , Tsvetelin Tsvetkov , Natasha Ivanova - ESTABLISHING A CONNECTION BETWEEN THE HUMAN PERIPHERAL NERVOUS SYSTEM AND AN UPPER LIMB MECHANICAL PROSTHESIS ______122 Gabriela Georgieva, Desislava Simeonova, Christina Grupcheva - LIMBAL STEM CELL TRANSPLANTATION FOR CORNEAL REGENERATION ______123 Denitsa Hristova , Maria Zhelyazkova-Savova - A SYSTEMATIC REVIEW OF RESEARCH ON N,N-DIMETHYLTRYPTAMINE ______124 Zekie Kasimova, Denitsa Koleva, Milena Avdzhiyska, Tulin Edirne - DEVELOPMENT OF CHRONIC TRAUMATIC ENCEPHALOPATHY IN ATHLETES AFTER REPETITIVE HEAD INJURY ______125 Darja Schlothauer , Anastasiia Subbotina , Stefan I. Ivanov - IUD INSERTION IMMEDIATELY AFTER DELIVERY ______126 Simona Panteleymonova , Ani Raynova, Radi Lukanov, Svetla Chilikova, Plamen Panayotov - MULTIDISCIPLINARY APPROACH IN COMORBID PATIENTS ______127 Miroslav Raikov , Milena Avdzhiyska , Silvia Ianakieva , Dimitar Raikov , Diyan Dimov - CONSERVATIVE TREATMENT OF PES EQUINOVARUS % HISTORY AND RECENT TRENDS 128 Keesha Cunningham, Nikolay Sapundzhiev - THE POSSESSION AND DISTRIBUTION OF VARIOUS TYPES OF CERUMEN IN DIFFERENT POPULATIONS AND ITS POSSIBLE ORIGINATION ______129 Magdalena Bliznakova, Boyko Matev, Pavel Todorov, Nikolay Nedev - CAPABILITIES OF REHABILITATION MEDICINE IN MUCOVISCIDOSIS PATIENTS TREATMENT ______130 Tanya Dimova , Lachezar Radev , Irena Michailova , Diana Zaimova - IN VITRO BIOACTIVITY OF SILVER!CONTAINING SOL!GEL GLASSES: FTIR ANALYSIS ______131 Oganes Vardanyan , Ivan Uzunov, Maya Radeva, Kaloyan Georgiev - PRINCIPLES OF PHARMACOKINETIC BOOSTING ______132 Stanila Stoeva, Iliyan Kolev, Yulichka Sabeva - RESEARCH ABOUT THE POSSIBILITY OF INCREASING THE BIOAVAILABILITY OF CAPECITABINE ______133 Stefanie Degen , Maria Dolores Franco Martinez, Alexander Hinev, Faidra Marazaki , Navneet Magon - VASALGEL™: A NOVEL REVERSIBLE NON-HORMONAL CONTRACEPTIVE FOR MEN ______134 Desislava Simeonova, Konstantin Ganchev, Gabriela Georgieva, Liliya Ilieva, Yana Manolova ! TOXIC KERATOPATHY ASSOCIATED WITH ABUSE OF TOPICAL ANESTHETICS ______135 Boyko Matev , George Stoyanov, Magdalena Bliznakova, Alice Renjilian, Radoslav Spasov - CHOOSING A PARTNER % DOES MALE PERSONALITY PLAY A ROLE IN BREAST SIZE PREFERENCES ______136 Malwin Werner , Nikoo Rahimy , Stefanka Racheva - SEXUAL ADVERSE EFFECTS OF FINASTERID 1MG FOR TREATMENT OF ANDROGENIC ALOPECIA IN MEN ______137 Elena Stoyanova , Elena Stoyanova, Ersin Ismail, Alexandra Stefanova, Svetoslav Dobrev, Dimcho Tomov - SILICOSIS – CLINICAL MANIFESTATION AND RELATION WITH OTHER PULMONARY AND NON-PULMONARY DISEASES ______138 Paola Kulicheva, Zhivko Apostolov, Liliya Raeva, Boris Botev, Dinnar Yahya - THE CONNECTION BETWEEN IBS, ANXIETY AND DEPRESSION ______139 Ralitsa Simeonova , Galina Dimova , Rosi Hristova , Anna Todorova - THE PHARMACIST’S RESPONSIBILITY IN REVERSING DRUG!INDUCED NUTRIENT DEPLETION ______140 Mehmet Fatih Aydın , Hakan Guzel - DETERMINATION OF RISK FACTORS FOR HYDATID DISEASE AMONG ANIMAL BREEDERS IN DİNAR-AFYONKARAHİSAR ______141 Ralitsa Simeonova , Iliya Zhelev , Konstantina Velikova , Galina Dimova 1, Rosi Hristova - PHYTOTHERAPY IN THE MANAGEMENT OF MENOPAUSE!ASSOCIATED VASOMOTOR SYMPTOMS ______142 Yosif Gerchev , Samuela Krasteva , Monika Yaneva , Dragomir Stoyanov , Zhivko Apostolov - REPROFILING OF ANTIPSYCHOTIC DRUGS FOR CANCER TREATMENT ______143 Monika Kalcheva, Hristo Stefanov , Damyan Iliev , Svetlin Varbanov , Yasen Yanev - A STUDY ON STRESS LEVELS, ANXIETY AND DEPRESSION IN STUDENTS AT THE MEDICAL UNIVERSITY OF VARNA ______144 Anastasiia Subbotina , Darja Schlothauer , Johanna Löhr , Elvira Nenashkina - RHESUS INCOMPATIBILITY IN EARLY MEDICAL ABORTION UP TO 8 WEEKS OF GESTATION "ARTICLE REVIEW# ______145 Ivelina Borisova , Stanislava Stoycheva, Iliyan Kolev - GADOLINIUM!CONTAINING CONTRAST AGENTS % NOT AS SAFE AS WE THOUGHT ______146 Daniel Zhafal , Daniela Angelova, Nikola Garipov, Teodora Stoyanova, Diana Petkova - SOMATOFORM SYMPTOM AND FACTITIOUS DISORDERS ______147 Stanislav Morfov , Petar Milkov , Borislav Zlatev , Veselin Marinov - OSTEOPLASTY IN SURGICAL TREATMENT OF CHRONIC EXOGENOUS OSTEOMYELITIS______148 Veselin Marinov, Stanislav Morfov, Plamen Minchev - HIP ARTHROPLASTY ! METHOD OF CHOICE FOR SOME TROCHANTERIC FRACTURES ______149 Trayan Marinov , Aleksandrina Varbanova, Marina Yordanova, Klementina Moneva , Maya Doychinova - SUCCESSFUL ROOT CANAL TREATMENT MANAGEMENT OF TAURODONT TEETH ______150 Martin Karamanliev , Anislav Gabarski, Chavdar Ivanov, Dobromir Dimitrov - CLINICAL EFFECTIVENESS AND COMPLICATION RATE OF CORE NEEDLE BREAST BIOPSY ______151 Denis Veliev , Adem Hadjimehmed , Svilena Rangelova , Mukates Velieva , Evelina Zlatanova-Kazakova - RESPIRATORY DYSFUNCTIONS IN ACROMEGALY. ACROMEGALY AND SLEEP APNEA ___ 152 Vasil Yordanov , Miglena Balcheva , Siyana Gradanska , Maria Dzhinova - ORAL MANIFESTATION OF SYSTEMIC DISEASES ______153 Georgi Stoyanov , Deyan Dzhenkov, Martina Kitanova, Ivan Shterev - CORRELATION BETWEEN KI!67 INDEX AND PATIENT SURVIVAL IN GLIOBLASTOMA MULTIFORME ___ 154 Alexandra Goncharova , Majid Shahbazi, Elis Ismail - STRESS URINARY INCONTINENCE IN WOMEN. LASER TREATMENT OPTIONS______155 Vasil Dimitrov , Elina Merashka , Nikola Bonchev, Gergana Ivanova , Dobromir Nguen - USING OF VAC PACK DRESSING FOR TEMPORARY CLOSURE OF AN OPEN ABDOMEN ___ 156 Plamen Angelov , Elena Stoyanova , Alexandra Stefanova, Dimana Mitsova , Anton Dinkov - TREATING CROHN’S DISEASE WITH THE MONOCLONAL ANTIBODY VEDOLIZUMAB __ 157 Samuela Krasteva , Yosif Gerchev, Dragomir Stoyanov, Monika Yaneva, Zhivko Apostolov - KETAMINE AND THE FUTURE OF NMDA ANTAGONISTS IN THE TREATMENT OF DEPRESSION ______158 Simona Nizorkova, Yavor Hinov, Irini Karatsoli, Ivan Valkadinov, Georgi Todorov - ENDOVASCULAR TREATMENT FOR UNRESECTABLE HEPATOCELLULAR CARCINOMA - TRANSARTERIAL CHEMOEMBOLIZATION (TACE) ______159 Aleksandrina Varbanova , Trayan Marinov , Marina Yordanova , Klementina Moneva, Maya Doychinova - COCONUT % THERAPEUTIC APPLICATIONS IN DENTAL MEDICINE ___ 160 Siyana Gradanska , Maria Dzhinova , Vasil Yordanov , Miglena Balcheva - GENOMIC TESTS GUIDING THE ADJUVANT SYSTEMIC THERAPY IN WOMEN WITH BREAST CANCER ____161 Ivanina Arabadzhieva , Teodora Karamfilova, Kiril Hristozov, Evelina Zlatanova-Kazakova - THYROTOXIC CRISIS % TREATMENT AND MANAGEMENT ______162 Siyana Ilieva , Ahmed Ahmed , Aylin Kerim , Kristiyana Kaleva , Rositsa Chamova - THE POTENTIAL ANTI-TUMOR BENIFITES OF NIGELLA SATIVA ______163 Sami Karagöz , Mehmet Fatih Aydın, Suleyman Gokmen - PHYSICAL, CHEMICAL AND MICROBIOLOGICAL QUALITY OF WATER SAMPLES IN KARAMAN PROVINCE ______164 Desislava Boyanova , Ivan Angelov , Zlatina Peteva - TOXIC AND THERAPEUTIC EFFECTS OF YESSOTOXIN AND DOMOIC ACID ______165 Konstantina Velikova , Denica Koleva , Galina Dimova , Ivelina Hristova , Rumen Iordanov - PREGNANCY WITH TETRALOGY OF FALLOT ______166 Georgi Shopov , Yordan Slavov , Ani Dzakova , Dimana Mitsova , Darina Hristova - THE LINK BETWEEN PROCESSED MEAT CONSUMPTION AND CANCER ______167 Radi Lukanov , Silvia Gancheva , Elizabet Miladinova , Dessyslava Nikolaeva , Maria Zhelyazkova-Savova - EXPERIMENTAL MODEL OF SUBCLINICAL VITAMIN K DEFICIENCY: ADAPTATION OF THE STUDY OF OSTEOCALCIN ______168 Karina Spechter , Mohammed El Samara , Mariya Negreva - ECG CHANGES IN PATIENTS WITH HYPOTHERMIA ______169 Alice Renjilian , George Stoyanov , Boyko Matev , Velizar Gaidardzhiev , Nikolay Sapundzhiev - PREAURICULAR SINUS ! INCIDENCE IN A BULGARIAN COHORT ______170 Evgeni Grigorov , Stanislav Kochev, Jivko Kolev - EXTERNAL REFERENCE PRICING SYSTEM FOR MEDICINES IN BULGARIA ______171 Dragomir Ivanov , Mustafa Dzhambazov , Stefan Stefanov , Tsonka Dimitrova - CERVICAL CANCER NOWADAYS. RESEARCH OF PREVENTION AND AWARENESS OF WOMEN BETWEEN 18!35 YEARS OF AGE ______172 Jyothis Sajan , Blagovesta Mitkova - PERIVASCULAR ADIPOSE TISSUE AND ITS CLINICAL SIGNIFICANCE ______173 Dajana Tsankova , Neli Ermenlieva , Gabriela Tsankova , Tatina Todorova , Mariya Rostamloo - BOTULINUM NEUROTOXIN-CLINICAL USES ______174 Turgay Kalinov , Anton Tonev , Alexander Zlatarov , Mehmed Hadzhiveli , Georgi Ivanov , Boris Andonov , Georgi Valentinov , Nikola Kolev , Valentin Ignatov , Krasimir Ivanov - LAPAROSCOPIC APPENDECTOMY VS. OPEN APPENDECTOMY % 5!YEAR EXPERIENCE ___175 GUIDELINES FOR AUTHORS ______176