An Overview of the State of Chinese Nanoscience and Technology
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Understanding the Initiation of the Publishing Process
Part 1 of a 3-part Series: Writing for a Biomedical Publication UNDERSTANDING THE INITIATION OF THE PUBLISHING PROCESS Deana Hallman Navarro, MD Maria D. González Pons, PhD Deana Hallman Navarro, MD BIOMEDICAL SCIENTIFIC PUBLISHING Publish New knowledge generated from scientific research must be communicated if it is to be relevant Scientists have an obligation to the provider of funds to share the findings with the external research community and to the public Communication Personal communication Public lectures, seminars, e-publication, press conference or new release ◦ Unable to critically evaluate its validity Publication ◦ Professional scientific journals – 1665 ◦ 1ry channel for communication of knowledge ◦ Arbiter of authenticity/legitimacy of knowledge Responsibility shared among authors, peer reviewers, editors and scientific community How to Communicate Information Publications, brief reports, abstracts, case reports, review article, letter to the editor, conference reports, book reviews… 1ry full-length research publication-1968 ◦ Definition: the first written disclosure of new knowledge that would enable the reader to: Repeat exactly the experiments described To assess fully the observations reported Evaluate the intellectual processes involved Development of the Manuscript To repeat exactly the experiments: ◦ Need a comprehensive, detailed methodology section To assess fully the observations: ◦ Need a very detailed results section With graphs, charts, figures, tables, … And full exposure of hard data Development -
From DNA Nanotechnology to Material Systems Engineering
PROGRESS REPORT DNA Nanotechnology www.advmat.de From DNA Nanotechnology to Material Systems Engineering Yong Hu and Christof M. Niemeyer* supramolecular networks. These devel- In the past 35 years, DNA nanotechnology has grown to a highly innovative opments have given rise to numerous and vibrant field of research at the interface of chemistry, materials science, so-called “DNA tiles” that can be used as biotechnology, and nanotechnology. Herein, a short summary of the state building blocks for the assembly through of research in various subdisciplines of DNA nanotechnology, ranging from sticky-end cohesion into discrete “finite” objects or periodic “infinite” 2D and 3D pure “structural DNA nanotechnology” over protein–DNA assemblies, periodic lattices.[4] However, since the nanoparticle-based DNA materials, and DNA polymers to DNA surface production of finite DNA nanostructures technology is given. The survey shows that these subdisciplines are growing from DNA tiles remained complicated,[5] ever closer together and suggests that this integration is essential in order to the development of the “scaffolded DNA initiate the next phase of development. With the increasing implementation origami” technique by Rothemund[6] is of machine-based approaches in microfluidics, robotics, and data-driven to be seen as an important milestone. Indeed, this method enabled the break- science, DNA-material systems will emerge that could be suitable for through of DNA nanotechology for the applications in sensor technology, photonics, as interfaces between technical fabrication of finite, programmable, and systems and living organisms, or for biomimetic fabrication processes. addressable nanostructures, thereby initi- ating a second wave of innovation in the field.[7] As discussed in Section 2, this set 1. -
Guide to Publication Policies of the Nature Journals
GUIDE TO PUBLICATION POLICIES OF THE NATURE JOURNALS Last updated on 30 April 2009. Editorial Policies NATURE JOURNALS' POLICIES ON PUBLICATION ETHICS Nature journals' authorship policy Being an author The Nature journals do not require all authors of a research paper to sign the letter of submission, nor do they impose an order on the list of authors. Submission to a Nature journal is taken by the journal to mean that all the listed authors have agreed all of the contents. The corresponding (submitting) author is responsible for having ensured that this agreement has been reached, and for managing all communication between the journal and all co-authors, before and after publication. Any changes to the author list after submission, such as a change in the order of the authors, or the deletion or addition of authors, needs to be approved by a signed letter from every author. Responsibilities of senior team members on multi-group collaborations The editors at the Nature journals assume that at least one member of each collaboration, usually the most senior member of each submitting group or team, has accepted responsibility for the contributions to the manuscript from that team. This responsibility includes, but is not limited to: (1) ensuring that original data upon which the submission is based is preserved and retrievable for reanalysis; (2) approving data presentation as representative of the original data; and (3) foreseeing and minimizing obstacles to the sharing of data, materials, algorithms or reagents described in the work. Author contributions statementsAuthors are required to include a statement of responsibility in the manuscript that specifies the contribution of every author. -
Small Wonders the US National Nanotechnology Initiative Has Spent Billions of Dollars on Submicroscopic Science in Its First 10 Years
NEWS FEATURE NATURE|Vol 467|2 September 2010 Simulation of the flow pattern for electrons travelling over a random nanoscale landscape. Small wonders The US National Nanotechnology Initiative has spent billions of dollars on submicroscopic science in its first 10 years. Corie Lok finds out where the money went and what the initiative plans to do next. ichard Smalley’s cheeks were gaunt and promised to conduct electricity better than It was a message that Washington was ready his hair was nearly gone when he testi- copper, but also had the potential to produce to hear. US President Bill Clinton formally fied before the US House of Representa- fibres 100 times stronger than steel at one- announced the initiative in 2000, with bipar- tives in June 1999. The Nobel laureate sixth of the weight. Smalley also predicted tisan support from Congress. The initiative R, HARVARD UNIV. HARVARD R, R E chemist had been diagnosed with non-Hodg- that the “very blunt tool” of chemotherapy that has faced some criticism in the decade since LL kin’s lymphoma a few months earlier, chemo- had ravaged his own body would be obsolete — most notably for its slowness to address E therapy was taking its toll, and the journey within 20 years, because scientists would engi- environmental, health and safety concerns H J. E. from Rice University in Houston, Texas, had neer nanoscale drugs that were “essentially about nanomaterials. But it has also created been exhausting. But none of that dimmed his cancer-seeking missiles” able more than 70 nano-related obvious passion for a subject that his listen- to target mutant cells with “As chemists, we academic or government ers found both mystifying and enthralling: minimal side effects. -
A Bioinspired and Hierarchically Structured Shape-Memory Material
ARTICLES https://doi.org/10.1038/s41563-020-0789-2 A bioinspired and hierarchically structured shape-memory material Luca Cera1, Grant M. Gonzalez1, Qihan Liu1, Suji Choi1, Christophe O. Chantre1, Juncheol Lee 2, Rudy Gabardi1, Myung Chul Choi2, Kwanwoo Shin3 and Kevin Kit Parker 1 ✉ Shape-memory polymeric materials lack long-range molecular order that enables more controlled and efficient actua- tion mechanisms. Here, we develop a hierarchical structured keratin-based system that has long-range molecular order and shape-memory properties in response to hydration. We explore the metastable reconfiguration of the keratin secondary struc- ture, the transition from α-helix to β-sheet, as an actuation mechanism to design a high-strength shape-memory material that is biocompatible and processable through fibre spinning and three-dimensional (3D) printing. We extract keratin protofibrils from animal hair and subject them to shear stress to induce their self-organization into a nematic phase, which recapitulates the native hierarchical organization of the protein. This self-assembly process can be tuned to create materials with desired anisotropic structuring and responsiveness. Our combination of bottom-up assembly and top-down manufacturing allows for the scalable fabrication of strong and hierarchically structured shape-memory fibres and 3D-printed scaffolds with potential applications in bioengineering and smart textiles. he growing demand of shape-memory devices in the fields of orders of magnitude greater than those of conventional systems16–20. civil engineering1, aerospace2, wearable technology3 and medi- This is achieved by starting from a non-destructive extraction of Tcal devices4,5 has galvanized research beyond the conventional keratin protofibrils from animal hair. -
30 Years of Moving Individual Atoms
FEATURES 30 YEARS OF MOVING INDIVIDUAL ATOMS 1 2 l Christopher Lutz and Leo Gross – DOI: https://doi.org/10.1051/epn/2020205 l 1 IBM Research – Almaden, San Jose, California, USA l 2 IBM Research – Zurich,¨ 8803 Ruschlikon,¨ Switzerland In the thirty years since atoms were first positioned individually, the atom-moving capability of scanning probe microscopes has grown to employ a wide variety of atoms and small molecules, yielding custom nanostructures that show unique electronic, magnetic and chemical properties. his year marks the thirtieth anniversary of the publication by IBM researchers Don Eigler and Erhard Schweizer showing that individ- Tual atoms can be positioned precisely into chosen patterns [1]. Tapping the keyboard of a personal computer for 22 continuous hours, they controlled the movement of a sharp tungsten needle to pull 35 individ- ual xenon atoms into place on a surface to spell the letters “IBM” (Figure 1). Eigler and Schweitzer’s demonstration set in motion the use of a newly invented tool, called the scanning tunneling microscope (STM), as the workhorse for nanoscience research. But this achievement did even more than that: it changed the way we think of atoms. m FIG. 2: The STM that Don Eigler and coworkers used to position atoms. The It led us to view them as building blocks that can be tip is seen touching its reflection in the sample’s surface. (Credit: IBM) arranged the way we choose, no longer being limited by the feeling that atoms are inaccessibly small. with just one electron or atom or (small) molecule. FIG. -
SJR Best Quartile Title Issn SJR H Index Country Publisher Q1 Nature
SJR Best Title Issn SJR H index Country Publisher Quartile Q1 Nature Biotechnology 15461696, 10870156 15,358 445 United Kingdom Nature Publishing Group Q1 Nature Materials 14764660, 14761122 14,344 483 United Kingdom Nature Publishing Group Q1 Nature Nanotechnology 17483387, 17483395 14,308 353 United Kingdom Nature Publishing Group Q1 Advanced Materials 09359648, 15214095 10,707 527 United States Wiley-Blackwell Q1 Nature Electronics 25201131 9,569 47 United Kingdom Nature Publishing Group Materials Science and Engineering: R: Q1 0927796X 8,366 146 Netherlands Elsevier BV Reports Q1 Materials Today 13697021 8,071 177 Netherlands Elsevier Institute of Electrical and Electronics Q1 IEEE Communications Surveys and Tutorials 1553877X 6,605 197 United States Engineers Inc. Q1 Nature Biomedical Engineering 2157846X 5,961 56 United States Nature Publishing Group Q1 Nano Energy 22112855 5,764 171 Netherlands Elsevier BV American Association for the Q1 Science Robotics 24709476 5,619 50 United States Advancement of Science Q1 Nano Today 17480132 5,586 143 Netherlands Elsevier Q1 ACS Nano 1936086X, 19360851 5,554 382 United States American Chemical Society Q1 Advanced Science 21983844 5,388 100 Germany Wiley-VCH Verlag Q1 Nano Letters 15306992, 15306984 4,853 488 United States American Chemical Society Q1 Cement and Concrete Research 88846 4,628 215 United Kingdom Elsevier Ltd. Q1 Materials Horizons 20516347, 20516355 4,322 81 United Kingdom Royal Society of Chemistry Q1 Annual Review of Biomedical Engineering 15239829, 15454274 4,142 133 United -
List Stranica 1 Od
list product_i ISSN Primary Scheduled Vol Single Issues Title Format ISSN print Imprint Vols Qty Open Access Option Comment d electronic Language Nos per volume Available in electronic format 3 Biotech E OA C 13205 2190-5738 Springer English 1 7 3 Fully Open Access only. Open Access. Available in electronic format 3D Printing in Medicine E OA C 41205 2365-6271 Springer English 1 3 1 Fully Open Access only. Open Access. 3D Display Research Center, Available in electronic format 3D Research E C 13319 2092-6731 English 1 8 4 Hybrid (Open Choice) co-published only. with Springer New Start, content expected in 3D-Printed Materials and Systems E OA C 40861 2363-8389 Springer English 1 2 1 Fully Open Access 2016. Available in electronic format only. Open Access. 4OR PE OF 10288 1619-4500 1614-2411 Springer English 1 15 4 Hybrid (Open Choice) Available in electronic format The AAPS Journal E OF S 12248 1550-7416 Springer English 1 19 6 Hybrid (Open Choice) only. Available in electronic format AAPS Open E OA S C 41120 2364-9534 Springer English 1 3 1 Fully Open Access only. Open Access. Available in electronic format AAPS PharmSciTech E OF S 12249 1530-9932 Springer English 1 18 8 Hybrid (Open Choice) only. Abdominal Radiology PE OF S 261 2366-004X 2366-0058 Springer English 1 42 12 Hybrid (Open Choice) Abhandlungen aus dem Mathematischen Seminar der PE OF S 12188 0025-5858 1865-8784 Springer English 1 87 2 Universität Hamburg Academic Psychiatry PE OF S 40596 1042-9670 1545-7230 Springer English 1 41 6 Hybrid (Open Choice) Academic Questions PE OF 12129 0895-4852 1936-4709 Springer English 1 30 4 Hybrid (Open Choice) Accreditation and Quality PE OF S 769 0949-1775 1432-0517 Springer English 1 22 6 Hybrid (Open Choice) Assurance MAIK Acoustical Physics PE 11441 1063-7710 1562-6865 English 1 63 6 Russian Library of Science. -
DNA Nanotechnology Meets Nanophotonics
DNA nanotechnology meets nanophotonics Na Liu 2nd Physics Institute, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany Max Planck Institute for Solid State Research, Heisenbergstrasse 1, 70569 Stuttgart, Germany Email: [email protected] Key words: DNA nanotechnology, nanophotonics, DNA origami, light matter interactions Call-out sentence: It will be very constructive, if more research funds become available to support young researchers with bold ideas and meanwhile allow for failures and contingent outcomes. The first time I heard the two terms ‘DNA nanotechnology’ and ‘nanophotonics’ mentioned together was from Paul Alivisatos, who delivered the Max Planck Lecture in Stuttgart, Germany, on a hot summer day in 2008. In his lecture, Paul showed how a plasmon ruler containing two metallic nanoparticles linked by a DNA strand could be used to monitor nanoscale distance changes and even the kinetics of single DNA hybridization events in real time, readily correlating nanoscale motion with optical feedback.1 Until this day, I still vividly remember my astonishment by the power and beauty of these two nanosciences, when rigorously combined together. In the past decades, DNA has been intensely studied and exploited in different research areas of nanoscience and nanotechnology. At first glance, DNA-based nanophotonics seems to deviate quite far from the original goal of Nadrian Seeman, the founder of DNA nanotechnology, who hoped to organize biological entities using DNA in high-resolution crystals. As a matter of fact, DNA-based nanophotonics does closely follow his central spirit. That is, apart from being a genetic material for inheritance, DNA is also an ideal material for building molecular devices. -
Small Wonders, Endless Frontiers
Small Wonders, Endless Frontiers A Review of the National Nanotechnology Initiative Committee for the Review of the National Nanotechnology Initiative Division on Engineering and Physical Sciences National Research Council NATIONAL ACADEMY PRESS Washington, D.C. NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. This material is based on work supported by the National Science Foundation under Grant No. CTS- 0096624. Any opinions, findings, and conclusions or recommendations expressed in it are those of the authors and do not necessarily reflect the views of the National Science Foundation. International Standard Book Number 0-309-08454-7 Additional copies of this report are available from: National Research Council 2101 Constitution Avenue, N.W. Washington, DC 20418 Internet, <http://www.nap.edu> Copyright 2002 by the National Academy of Sciences. All rights reserved. Printed in the United States of America Front cover: Three-dimensional scanning tunneling microscope image of a man-made lattice of cobalt atoms on a copper (111) surface. Courtesy of Don Eigler, IBM Almaden Research Center. Back cover: A nanoscale motor created by attaching a synthetic rotor to an ATP synthase. Reprinted with permission of the American Association for the Advancement of Science from Soong et al., Science 290, 1555 (2000). © 2000 by AAAS. -
ABSTRACT MARTIN, KELLY NORRIS. Visual
ABSTRACT MARTIN, KELLY NORRIS. Visual Research: Introducing a Schema for Methodologies and Contexts. (Under the direction of Victoria J. Gallagher.) Studying the visual has become tremendously important to many disciplines because images express a range of human experience sometimes ambiguously articulated in verbal discourse, namely, “spatially oriented, nonlinear, multidimensional, and dynamic” human experiences (Foss, 2005, p. 143). In fact, the power of the image to plainly communicate occurs not “in spite of language’s absence but also frequently because of language’s absence” (Ott & Dickinson, 2009, p. 392). Presently, the challenge for visual research is that scholars investigate images from varied disciplines with separate and distinctive methods with little discussion or exchange across fields. Furthermore, more disciplines are requiring students to take courses in visual communication and more professors are being hired to teach those courses. However, these visual communication professors have nowhere to go (in the United States) in order to become prepared to teach and conduct research in visual communication. They enroll in programs in journalism and mass communication, linguistics, sociology, social psychology, anthropology, and so on. Then, they either adapt what they learn from these fields to the field of visual communication or they teach themselves about the methods, theories, and literature of visual communication. This project focused on comparing and contrasting the strengths and limitations of various visual research -
Suzanne Pfeffer
July 2010 ASBMB PreSidentiAl PriMer: Suzanne Pfeffer American Society for Biochemistry and Molecular Biology AAdjuvdjuvAAntnt IImmunothermmunotherAApypy ususIIngng KKrnrn70007000 KRN7000 (α-Galactosyl Ceramide) Avanti Number 867000 Supplier: Funakoshi Co. Ltd. Hepatic metastasis is a major clinical problem in cancer treatment. We examined antitumor ac- tivity of alpha-galactosylceramide (KRN7000) on mice with spontaneous liver metastases of re- ticulum cell sarcoma M5076 tumor cells (spontaneous metastasis model). In this model, all mice that were s.c. challenged with one million tumor cells developed a solid s.c. mass by day 7 and died of hepatic metastases. In the current study, we administered 100 microg/kg of KRN7000 to the model mice on days 7, 11, and 15. This treatment suppressed the growth of established liver metastases and resulted in the prolongation of survival time. Fluorescence-activated cell sorter analysis of phenotypes of spleen cells, hepatic lymphocytes, and regional lymph node cells around the s.c. tumor revealed that CD3+NK1.1+ (NKT) cells increased in hepatic lym- phocytes of the KRN7000-treated mice. Cytotoxic activity and IFN-gamma production of hepatic lymphocytes were augmented in comparison with those of spleen cells and regional LN cells. At the same time, interleukin (IL)-12 production of hepatic lymphocytes was markedly enhanced. Neutralization of IL-12 using a blocking monoclonal antibody diminished the prolonged survival time. These results showed that the in vivo antitumor effects of KRN7000 on spontaneous liver metastases were dependent on the endogenous IL-12 production, where NKT cells in the liver are suggested to be involved. Adjuvant immunotherapy using KRN7000 could be a promising modality for the prevention of postoperative liver metastases.