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Quick Guide: NLL Urine Drugs of Abuse Screens

Potential Drug * Cut-off Can Cannot Detect False Class or Name (ng/mL) Detect Positive Specific For: l-Amphetamine d-Amphetamine Methylenedioxyamphetamine Benzphetamine d-Methamphetamine (MDA) **Cross-reactivity with: Amphetamines 500 Methylenedioxymethamphetamine Selegiline d,l-Amphetamine (MDMA) d,l-Methamphetamine Methylenedioxyethyl- l-Methamphetamine amphetamine (MDEA) Specific For: **Cross-reactivity with:

Allobarbital

Amobarbital 5-Ethyl-5-(4-hydroxyphenyl) 200 barbituric acid Thiopental

Specific For:

**Cross-reactivity with:

Clorazepate N-Desalkylflurazepam N-Desmethyldiazepam 7-aminoclonazepam 7-aminoflunitrazepam

Halazepam α-Hydroxyalprazolam α-Hydroxyalprazolam glucuronide 200 1-N-Hydroxyethylflurazepam α-Hydroxytriazolam Lorazepam glucuronide Norchlordiazepoxide glucuronide glucuronide Nordiazepam Oxazepam Temazepam

Version 1 Release Date: 2012-05

Quick Guide: NLL Urine Drugs of Abuse Screens

Potential Drug * Cut-off Can Cannot Detect False Class or Name (ng/mL) Detect Positive Specific For: ∆9-tetrahydrocannabinol (∆9-THC)

**Cross-reactivity with: 9 8-β-11-Dihydroxy- ∆ -THC 8-β-11-Hydroxy- ∆9-THC Synthetic cannabinoids: Cannabinoid 50 11-Hydroxy- ∆8-THC JWH-018; CP 47,497; JWH-073; 11-Hydroxy- ∆9-THC JWH-200; Cannabicyclohexanol 11-nor- ∆9-THC-9-carboxylic acid 9-Carboxy-11-nor- ∆9-THC- glucuronide

Specific For:

Benzoylecgonine Cocaine (parent drug) Cocaine 300 (metabolite of cocaine) Ecgonine

Specific For: Ofloxcin Levallorphan (Floxin®) **Cross-reactivity with: Levorphanol Codeine Dihydrocodeine Meperidine Levofloxacin Hydrocodone Opiates 300 Nalorphine (Levaquin®) Hydromorphone Naloxone 6-acetylmorphine Oxycodone Food products Morphine-3-glucuronide Oxymorphone containing poppy seeds Specific For: Phencyclidine **Cross-reactivity with: Dextromethorphan

Dextrorphan 1-[1-(2-Thienyl)-cyclohexyl] Mesoridazine morpholine (TCM) 1-(1-Phenylcyclohexyl) morpholine (PCM) N,N-Diethyl-1- Phencyclidine 25 1-(1-Phenylcyclohexyl) pyrrolidine Dextromethorphan phenylcyclohexylamine (PCDE) (PCPy) 4-Phenyl-4-piperidinocyclohexanol 1-(4-Hydroxypiperidino) (PPC) phenylcyclohexane 1-[1-(2-Thienyl)-cyclohexyl] piperidine (TCP) 1-[1-(2-Thienyl)-cyclohexyl] pyrrolidine (TCPy)

* Lowest Concentration Detectable **Indicates parent drugs and/or metabolites with the drug class that demonstrate greater than 50% cross-reactivity. If the urine contains more than one compound detected by the assay, lower concentrations can combine and have additive effects which may produce detection equivalent to or greater than the detectable cutoff concentration.

Version 1 Release Date: 2012-05