Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest Arenberg, Douglas A Associate Pulmonary & Critical Care , Internal Mentor Angiogenesis, the role of M.D. Professor Medicine migration inhibitory factor (MIF) in cancer, tumor microenvironment Aronoff, David Associate Int Med-Infectious Diseases Mentor Translation and basic M.D. Professor (Microbiology & ) science studies of host- (Associate microbial interactions Professor) Athey, Brian D Professor & Computational Medicine and Bioinformatics Mentor Integrative Biomedical Ph.D. Chair Informatics and Translational Bioinformatics Burant, Charles Professor Metabolism, Endo & Diabetes Mentor Metabolomics and system M.D., Ph.D., M.S. (Professor) (Molec & Integrative Physiology ) biology in disease states, including diabetes. Chervin, Ronald David Professor Department Mentor Pathogenesis and diagnosis of sleep-related disorders Cooke, Colin R Assistant Pulmonary & Critical Care Medicine, Internal Mentor ICU organization and Professor Medicine efficiency in care delivery Curtis, Jeffrey L Professor Pulmonary & Critical Care Medicine, Internal Mentor Regulation of pulmonary M.D. Medicine immunity; translational research in COPD Dressler, Gregory R Collegiate Department Mentor Genetic and epigenetic Ph.D. Professor mechanisms that regulate the development of complex organisms and tissues Duckett, Colin S Professor Pathology Mentor Regulation of apoptosis; role Ph.D. (Professor) (Int Med) of apoptotic regulators in inflammation and fibrosis. Flaherty, Kevin R Professor Pulmonary & Critical Care Medicine, Internal Assoc. Director Patient oriented clinical and M.D., M.S. Medicine Mentor translational research in interstitial lung disease. Fox, David A Professor Int Med- Mentor Tissue remodeling and M.D. destruction in autoimmune disease.

Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest Gumucio, Deborah L Professor Cell & Develop Biology Mentor Cell:cell interactions in Ph.D., M.P.H. intestinal organogenesis and homeostasis. Han, Meilan K Clinical Asst Pulmonary & Critical Care Medicine, Internal Mentor Clinical/translational studies Prof Medicine in COPD, interstitial lung diseases. Hayward, Rodney A Professor Department Mentor Health services research in M.D. (Professor) (Health Management and Policy) outcome and quality measurement. He, Yongqun Associate Unit For Lab Animal Medicine Mentor Microbial pathogenesis, D.V.M., Ph.D. Professor (Microbiology and Immunology ) bioinformatics approaches to (Associate study host-pathogen Professor) interactions. Hershenson, Marc B Professor /Pulmonary Mentor Pathogenesis of rhinovirus- M.D. (Professor) (Molecular & Integrative Physiology) induced exacerbations of chronic airways diseases including asthma and COPD;

Role of mesenchymal stem cells in lung injury and repair Hogaboam, Cory M Professor Pathology Department Mentor Innate and adaptive immune Ph.D. mechanisms that promote abnormal remodeling and scarring responses in the lung. Horowitz, Jeffrey C Asst Pulmonary & Critical Care Medicine, Internal Mentor Regulation of mesenchymal Professor Medicine cell survival and apoptosis. Huffnagle, Gary B Professor Pulmonary & Critical Care Medicine, Internal Assoc. Director Pulmonary immunity; Ph.D. (Professor) Medicine(Microbiology and Immunology) Mentor microbiota and mucosal tolerance. Iwashyna, Theodore Asst Pulmonary & Critical Care Medicine, Internal Mentor Long term outcomes in Professor Medicine severe sepsis; optimizing ICU organization. Kazerooni, Ella A Professor Department Mentor The study of multidetector M.D., M.S. CT for diagnosis, staging

Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest and treatment of diffuse lung disease. Keshamouni, Venkateshwar Assistant Pulmonary & Critical Care Medicine, Internal Mentor Epithelial-mesenchymal Ph.D., M.S. Professor Medicine transitions in cancer; systems biology approaches for investigating tumor microenvironment. Kim, Kevin K Asst Pulmonary & Critical Care Medicine, Internal Mentor Basic mechanisms of Professor Medicine pulmonary fibrosis; transgenic mouse modeling. Krebsbach, Paul H Professor Biologic And Materials Sciences Mentor Cell and molecular biology of D.D.S., Ph.D. (Professor) (Biomedical Engineering) stem cells; tissue engineering. Kunkel, Steve L Professor Pathology Department Mentor Cytokine networks in Ph.D., M.S. (Associate (Graduate School Administration) immune/inflammatory lung Dean) disease and host defenses. Lama, Vibha N Associate Pulmonary & Critical Care Medicine, Internal Mentor Clinical predictors of onset M.D., M.S. Professor Medicine and course of fibrotic lung diseases; mesenchymal stem cells in chronic rejection. Langa, Kenneth M Professor Int Med-General Medicine Mentor Cognitive impairment in M.D., Ph.D. (Professor) (Institute for Social Research) medical illness. Li, Jun Asst Human Genetics Mentor Genetic association studies; Ph.D. Professor (CCMB-Infrastru) gene expression analyses; (Res Asst integrated analyses of large Professor) datasets. LiPuma, John Joseph Professor Pediatrics/Infectious Diseases Mentor Epidemiology, natural history M.D. (ASSOCIATE (Pediatric & Comm Diseases Dept) and virulence of CHAIR) Burkholderia cepacia comlex in cystic fibrosis. Liberzon, Israel Professor Mentor Neurobiology of stress and M.D. (Professor) (LSA Psychology) trauma in human disease. Lukacs, Nicholas W Professor Pathology Department Mentor T cell immunology; allergic

Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest Ph.D., M.S. (Assistant ( Administration) and viral induced airway Dean) inflammation. Martinez, Fernando Jose Professor Pulmonary & Critical Care Medicine, Internal Mentor Clinical/translational studies M.D., M.S. Medicine in interstitial lung disease, COPD, and lung transplantation. Moore, Bethany B Professor Pulmonary & Critical Care Medicine, Internal Mentor Chemokine and eicosanoid Ph.D. ( Professor) Medicine (Microbiology and Immunology) regulation of pulmonary fibrosis Innate and adaptive pulmonary host defense defects following bone marrow transplantation Murray, Susan Associate Biostatistics Department Mentor Biostatistical analysis in Sc.D. Professor clinical trials. Nunez, Gabriel Professor Pathology Mentor Node like receptors in M.D. pulmonary immunity; microbiota in mucosal immunity. Olszewski, Michal A Research Internal Medicine Mentor Host-pathogen interactions D.V.M., Ph.D. Investigator (FinOps Payroll Office) in fungal pneumonia. (PROF MISC (TEMP)) Omenn, Gilbert S Professor Of Comp Med and Bioinformatics Mentor Cancer proteomics and M.D., Ph.D. Medicine (Human Genetics) chemoprevention; (Professor of pharmacogenetics and Human pharmacogenomics. Genetics) Osterholzer, John J., M.D. Asst Pulmonary & Critical Care Medicine, Internal Mentor Innate and acquired Professor Medicine immunity in fungal pneumonia. Peters-Golden, Marc Professor Pulmonary & Critical Care Medicine, Internal Mentor Arachidonic acid metabolism M.D. Medicine in lung cells; eicosanoid biology in host defense and

Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest inflammatory/fibrotic lung disease. Phan, Sem H Professor Pathology Mentor Fibroblast/myofibroblast M.D., Ph.D. biology; mesenchymal stem cells. Pinsky, David Professor Internal Medicine Mentor Mechanisms of ischemic M.D. (Professor) (Molec & Integrative Physiology) vascular injury and protection. Richardson, Bruce C Professor Int Med-Rheumatology Mentor Chromatin structure in M.D., Ph.D. autoimmunity, cancer and fibrosis. Richardson, Caroline R Assistant Department Of Mentor Health services research in M.D. Professor (LSA Women's Studies) risk factor modification, (TECHNICAL health behavior change. MISC (TEMP)) Saint, Sanjay K Professor Internal Medicine Mentor Health services research in M.D., M.P.H. (Research (Ann Arbor VA Medical Center) patient safety and hospital- Scientist) acquired infections. Samuelson, Linda C Professor Molec & Integr Physi Mentor Notch-mediated regulation of Ph.D. (Professor) (Internal Medicine ) epithelial cell biology; transgenic mouse modeling. Schloss, Patrick D Associate Microbiology & Immunology Mentor Bioinformatic analysis of Ph.D. Professor host-pathogen interactions within the microbiome. Schmidt, Thomas M Professor Int Med-Infectious Diseases Mentor Microbial diversity, high- Ph.D., M.S. (Professor) (LSA Ecology & Evolutionary Bio ) throughput cultivation, bacterial physiology and the human microbiome. Sisson, Thomas Harold Associate Pulmonary & Critical Care Medicine, Internal Mentor Plasminogen system in M.D. Professor Medicine acute lung injury and fibrosis. Standiford, Theodore J Professor Pulmonary & Critical Care Medicine, Internal Director Toll like receptors in innate M.D. Medicine Mentor lung immunity; translational

Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest research in sepsis and acute lung injury. Stringer, Kathleen A., Ph.D. Assoc Clin, Soc & Admin Sci Mentor Metabolomics in sepsis and Professor (UMH Inpatient Pharmacy Svcs) acute lung injury; (PHARMACIS coagulation cascade in ALI. T-STAFF (TEMP)) Swanson, Joel A Professor Microbio & Immun Mentor Regulation of endocytosis Ph.D., M.S. and phagocytosis in macrophages. Swanson, Michele S Professor Microbiology And Immunology Mentor Host-pathogen interactions Ph.D., M.S. in Legionella pneumophila infection; autophagy. Takayama, Shuichi Professor Biomedical Engineering Mentor Microscale tissue Ph.D., M.S. (Professor) (Macromolecular Sci & Engr) engineering and cell biology. Microfluidics. Nanofluidics and single molecule DNA manipulation. High throughput screening. Vijan, Sandeep Assoc Int Med-General Medicine Mentor Diabetes outcomes, risk M.D. Professor (Med Ed/Towsley Ctr Activities) sratification, quality (TECHNICAL measurement and cost- MISC effectiveness (TEMP)) Weir, David R., Ph.D. Research Institute for Social Research Mentor Health services research in Professor long term patient outcomes. Wellik, Deneen Marie Associate Int Med, Molecular Medicine & Genetics Mentor Function of Hox genes Ph.D. Professor (Cell & Develop Bio) during mammalian (Associate organogenesis, especially in Professor) the integration of the musculoskeletal system and in fracture repair; kidney, pancreas and gut morphogenesis.

Table 2. Participating Faculty Members

Name/Degree(s) Rank Primary (& Secondary ) Appointment (s) Role in Program Research Interest White, Eric S Assoc Pulmonary & Critical Care Medicine, Internal Mentor Extracellular matrix, M.D. Professor Medicine pulmonary fibrosis, and (Assoc fibroblast biology. Professor) Young, Vincent Bensan Associate Internal Medicine/Infectious Diseases Mentor The microbiome in acute and M.D., Ph.D. Professor (Microbiology and Immunology) chronic gastrointestinal (Associate illness. Professor)