www.millionsmissing.de ME/CFS Research 2015-2019 1/40 31st Oct 2019
Author Year Title Puplication PMID Link Topic Subtopic
Murga I and 2019 From neurasthenia to post-exertion disease: Aten Primaria 31182238 https://www.ncbi. 01. Nomenclature Lafuente JV Evolution of the diagnostic criteria of chronic nlm.nih.gov/pub and definition fatigue syndrome/myalgic encephalomyelitis med/31182238
O’Leary D 2019 Ethical classification of ME/CFS in the United Bioethics 30734339 https://www.ncbi. 01. Nomenclature Kingdom nlm.nih.gov/pub and definition med/30734339
Scartozzi S et al. 2019 Myalgic encephalomyelitis and chronic fatigue Fatigue: https://www.tandf 01. Nomenclature syndrome case definitions: effects of requiring a Biomedicine, online.com/doi/a and definition substantial reduction in functioning Health & bs/10.1080/2164 Behavior 1846.2019.16008 Vol 7, 2019 - 25 Issue 2 Twisk FNM 2019 Myalgic Encephalomyelitis, Chronic Fatigue Curr Rheumatol 31073713 https://www.ncbi. 01. Nomenclature Syndrome, and Chronic Fatigue: Three Distinct Rep nlm.nih.gov/pub and definition Entities Requiring Complete Different Approaches med/31073713
Howard H 2018 Recent insights into 3 under recognized Canadian Family 29898928 https://www.ncbi. 01. Nomenclature conditions: Myalgic encephalomyelitis–chronic Physician 64 (6): nlm.nih.gov/pmc/ and definition fatigue syndrome, fibromyalgia, and 413-415 articles/PMC599 environmental sensitivities– multiple chemical 9262/ sensitivity
Sharif K, et al 2018 On chronic fatigue syndrome and nosological Clinical 29417255 https://www.ncbi. 01. Nomenclature categories Rheumatology nlm.nih.gov/pub and definition med/29417255
Twisk F 2018 Dutch Health Council Advisory Report on Myalgic Diagnostics 8 (2) 29772739 https://www.ncbi. 01. Nomenclature Encephalomyelitis and Chronic Fatigue nlm.nih.gov/pub and definition Syndrome: Taking the Wrong Turn med/29772739
Twisk F 2018 Myalgic Encephalomyelitis (ME) or What? An Diagnostics 8 (3) 30205585 https://www.ncbi. 01. Nomenclature Operational Definition nlm.nih.gov/pub and definition med/30205585
Twisk F 2018 Myalgic Encephalomyelitis or What? The Diagnostics 9 (1) https://www.mdpi 01. Nomenclature International Consensus Criteria .com/2075- and definition 4418/9/1/1
Jason LA, et al. 2017 Clinical Criteria Versus a Possible Research Fatigue: 29062593 https://www.ncbi. 01. Nomenclature Case Definition in Chronic Fatigue Biomedicine, nlm.nih.gov/pub and definition Syndrome/Myalgic Encephalomyelitis Health and med/29062593 Behaviour 5 (2): 89-102. Nacul L, et al. 2017 Differing case definitions point to the need for an Fatigue: 29250461 https://www.ncbi. 01. Nomenclature accurate diagnosis of myalgic Biomedicine, nlm.nih.gov/pub and definition encephalomyelitis/chronic fatigue syndrome Health and med/29250461 Behaviour 5 (1): 1-4. Sunnquist M, et 2017 A Comparison of Case Definitions for Myalgic Journal of 29104961 https://www.ncbi. 01. Nomenclature al. Encephalomyelitis and Chronic Fatigue Syndrome Chronic nlm.nih.gov/pub and definition Disorders and med/29104961 Management 2 (2). World Health 2016 Groups that were involved in ICD-11 Revision International http://www.who.in 01. Nomenclature Organisation Process Classification of t/classifications/ic and definition Diseases 10 d/en/
Jason LA, et al 2016 Are Myalgic Encephalomyelitis and Chronic Journal of Health 24510231 https://www.ncbi. 01. Nomenclature fatigue syndrome different illnesses? A Psychology nlm.nih.gov/pmc/ and definition preliminary analysis 21(1): 3-15 articles/PMC412 5561/
Asprusten TT, et 2015 Study findings challenge the content validity of the Acta Paediatrica 25640602 https://www.ncbi. 01. Nomenclature al. Canadian Consensus Criteria for adolescent 104 (5):498-503 nlm.nih.gov/m/pu and definition chronic fatigue syndrome bmed/25640602/
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Institute of 2015 Beyond Myalgic Encephalomyelitis/Chronic The National 25695122 https://www.ncbi. 01. Nomenclature Medicine Fatigue Syndrome Academies nlm.nih.gov/pub and definition Press med/25695122
Jason LA, et al 2015 Myalgic Encephalomyelitis: Symptoms and Curr 26411464 https://www.ncbi. 01. Nomenclature biomarkers Neuropharmacol. nlm.nih.gov/pub and definition 13(5):701-34 med/26411464
Jason LA, et al. 2015 Reflections on the Institute of Medicine’s systemic Polish Archives 26176405 https://www.ncbi. 01. Nomenclature exertion intolerance disease of Internal nlm.nih.gov/pmc/ and definition Medicine, 125 (7- articles/PMC482 8): 576-581 6027/
Lancet, The 2015 What’s in a name? Systemic exertion intolerance The Lancet 385 http://www.thelan 01. Nomenclature disease (9969): 663 cet.com/journals/ and definition lancet/article/PII S0140- 6736(15)60270- 7/fulltext Clayton EW. 2015 Beyond Myalgic encephalomyelitis/chronic fatigue JAMA 313 (11): https://jamanetw 01. Nomenclature syndrome: An IOM report on redefining an illness 1101-1102 ork.com/journals/ and definition jama/article- abstract/2118591
Chu L, et al. 2019 Onset Patterns and Course of Myalgic Front Pediatr 30805319 https://www.ncbi. 02. Epidemiology Encephalomyelitis/Chronic Fatigue Syndrome nlm.nih.gov/pub med/30805319
Comerford B and 2019 Medically Documenting Disability in Myalgic Front Pediatr 31334205 https://www.ncbi. 02. Epidemiology Podell R Encephalomyelitis/Chronic Fatigue Syndrome nlm.nih.gov/pub (ME/CFS) Cases med/31334205
Fatt S, et al. 2019 The Invisible Burden of Chronic Fatigue in the Curr Rheumatol https://link.spring 02. Epidemiology Community: a Narrative Review Rep er.com/article/10. 1007/s11926- 019-0804-2
Slomko J et al. 2019 Prevalence and characteristics of chronic fatigue BMJ Open 30850404 https://www.ncbi. 02. Epidemiology syndrome/myalgic encephalomyelitis (CFS/ME) in nlm.nih.gov/pub Poland: a cross-sectional study med/30850404
Valdez AR, et al. 2019 Estimating Prevalence, Demographics, and Costs Front Pediatr 30671425 https://www.ncbi. 02. Epidemiology of ME/CFS Using Large Scale Medical Claims nlm.nih.gov/pub Data and Machine Learning med/30671425
Collin SM, et al. 2017 Trends in the incidence of chronic fatigue Journal of the 28358988 https://www.ncbi. 02. Epidemiology syndrome and fibromyalgia in the UK, Royal Society of nlm.nih.gov/pmc/ 2001–2013: a Clinical Practice Research Datalink Medicine 110 (6): articles/PMC549 study 231-244. 9564/
Evans M and 2018 Onset patterns of chronic fatigue syndrome and Research on http://www.opena 02. Epidemiology Jason L myalgic encephalomyelitis Chronic ccessjournals.co Diseases 2 (1): m/articles/Onset 001-0030 %20patterns%20 of%20chronic%2 0fatigue%20synd rome%20and%2 0myalgic%20enc ephalomyelitis.pd f
Estevez-Lopez 2018 Prevalence and incidence of myalgic BMJ Open 8 (9): 30181183 https://www.ncbi. 02. Epidemiology F, et al encephalomyelitis/chronic fatigue syndrome in e020817 nlm.nih.gov/pub Europe-the Euro-epiME study from the European med/30181183 network EUROMENE: a protocol for a systematic review Strassheim VJ, 2018 Defining the prevalence and symptom burden of BMJ Open 8 (9) 30232103 https://www.ncbi. 02. Epidemiology et al those with selfreported severe chronic fatigue nlm.nih.gov/pub syndrome/myalgic encephalomyelitis (CFS/ME): a med/30232103 two-phase community pilot study in the North East of England Boneva RS et al. 2019 Endometriosis as a Comorbid Condition in Front Pediatr https://doi.org/10 03. Co-morbidity Chronic Fatigue Syndrome (CFS): Secondary .3389/fped.2019. Analysis of Data From a CFS Case-Control Study 00195
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Natelson BH et 2019 The effect of comorbid medical and psychiatric Annuals in 31642345 https://www.ncbi. 03. Co-morbidity al. diagnoses on chronic fatigue syndrome Medicine nlm.nih.gov/pub med/31642345
Natelson BH 2019 Myalgic Encephalomyelitis/Chronic Fatigue Clin Ther 30795933 https://www.ncbi. 03. Co-morbidity Syndrome and Fibromyalgia: Definitions, nlm.nih.gov/pub Similarities, and Differences med/30795933
Tsai SY, et al. 2019 Increased risk of chronic fatigue syndrome in J Transl Med 30795765 https://www.ncbi. 03. Co-morbidity patients with inflammatory bowel disease: a nlm.nih.gov/pub population-based retrospective cohort study med/30795765
Castro-Marrero 2017 Comorbidity in Chronic Fatigue Syndrome/Myalgic Psychosomatics 28596045 https://www.ncbi. 03. Co-morbidity J, et al. Encephalomyelitis: A Nationwide Population- 58 (2): 533-543. nlm.nih.gov/pub Based Cohort Study. med/28596045
Daniels J, et al. 2017 Anxiety and depression in chronic fatigue Psychology and 28244209 https://www.ncbi. 03. Co-morbidity syndrome/myalgic encephalomyelitis (CFS/ME): Psychotherapy nlm.nih.gov/pub Examining the incidence of health anxiety in 90 (3): 502-509. med/28244209 CFS/ME.
Loades ME, et 2017 The presence of co-morbid mental health Clinical 29096528 https://www.ncbi. 03. Co-morbidity al. problems in a cohort of adolescents with chronic Childhood nlm.nih.gov/pub fatigue syndrome. Psychology and med/29096528 Psychiatry 1: 13591045177363 57 McManimen SL 2017 Post-Exertional Malaise in Patients with ME and SRL Neurology 28603794 https://www.ncbi. 03. Co-morbidity and Jason LA. CFS with Comorbid Fibromyalgia and nlm.nih.gov/pmc/ Neurosurgery 3 articles/PMC546 (1): 22-27. 4757/
Litleskare S, et al 2018 Prevalence of Irritable Bowel Syndrome and Clinical 29378314 https://www.ncbi. 03. Co-morbidity Chronic Fatigue 10 Years After Giardia Infection Gastroenterology nlm.nih.gov/pub and Hepatology med/29378314
Lacerda EM, et 2018 The UK ME/CFS Biobank: a disease-specific Front. Neurol., https://doi.org/10 04. Biomedical 04.01 Biobank al biobank for advancing clinical research into .3389/fneur.2018 Research UK ME/CFS myalgic encephalomyelitis/chronic fatigue .01026 syndrome
Lacerda EM, et 2017 The UK ME/CFS Biobank for biomedical research Open Journal of 28649428 https://www.ncbi. 04. Biomedical 04.01 Biobank al. on Myalgic Encephalomyelitis/Chronic Fatigue Bioresources 4: nlm.nih.gov/pmc/ Research UK ME/CFS Syndrome (ME/CFS) and Multiple Sclerosis 4. articles/PMC548 2226/
Scheibenbogen 2017 The European ME/CFS Biomarker Landscape Journal of 28747192 https://www.ncbi. 04. Biomedical 04.02 Biomarker C, et al. project: an initiative of the European network Translational nlm.nih.gov/pmc/ Research Landscape EUROMENE Medicine 15: articles/PMC553 Project 162. 0475/
Nelson MJ et al. 2019 Evidence of altered cardiac autonomic regulation Medicine 31651868 https://www.ncbi. 04. Biomedical 04.03 Cardiac in myalgic encephalomyelitis/chronic fatigue (Baltimore) 98 nlm.nih.gov/pub Research Function syndrome: A systematic review and meta- (43 med/31651868 analysis
Davenport T et 2019 Chronotropic Intolerance: An Overlooked Front Pediatr https://www.fronti 04. Biomedical 04.03 Cardiac al. Determinant of Symptoms and Activity Limitation ersin.org/articles/ Research Function in Myalgic Encephalomyelitis/Chronic Fatigue 10.3389/fped.20 Syndrome? 19.00082/full
Larson B et al. 2019 Reproducibility of Measurements Obtained During Cardiopulmonary https://journals.lw 04. Biomedical 04.03 Cardiac Cardiopulmonary Physical Therapy w.com/cptj/Abstr Research Function Exercise Testing in Individuals With Fatiguing J. Oct 2019 - Vol act/publishahead Health Conditions: A Case Series 30 - Issue 4 - p /Reproducibility_ 145–152 of_Measurement s_Obt Boissoneault J, 2018 Cerebral blood flow and heart rate variability Brain Imaging 29855991 https://www.ncbi. 04. Biomedical 04.03 Cardiac et al predict fatigue severity in patients with chronic and Behaviour nlm.nih.gov/pub Research Function fatigue syndrome 13 (3): 789797 med/29855991
Hodges LD, et 2017 Physiological measures in participants with Clinical 28782878 https://www.ncbi. 04. Biomedical 04.03 Cardiac al. chronic fatigue syndrome, multiple sclerosis and Physiology and nlm.nih.gov/pub Research Function healthy controls following repeated exercise: a Functional med/28782878 pilot study. Imaging.
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Tomas C, et al. 2017 Elevated brain natriuretic peptide levels in chronic Open Heart 4 29344367 https://www.ncbi. 04. Biomedical 04.03 Cardiac fatigue syndrome associate with cardiac (2): e000697. nlm.nih.gov/pmc/ Research Function dysfunction: a case control study articles/PMC576 1285/
Bozzini S, et al 2018 Cardiovascular characteristics of chronic fatigue Biomedical 29399336 https://www.ncbi. 04. Biomedical 04.03 Cardiac syndrome Reports 8 (1): 26- nlm.nih.gov/pub Research Function 30 med/29399336
Campen CM, et 2018 Blood volume status in CFS/ME correlates with Frontiers in https://doi.org/10 04. Biomedical 04.03 Cardiac al the presence or absence of orthostatic symptoms Paediatrics .3389/fped.2018. Research Function 00352
Campen CM and 2018 The Abnormal Cardiac Index and Stroke Volume Journal of https://tinyurl.co 04. Biomedical 04.03 Cardiac Visser FC Index Changes During a Normal Tilt Table Test in Thrombosis and m/y5nb9dyr Research Function ME/CFS Patients Compared to Healthy Circulation 107 Volunteers, are Not Related to Deconditioning
Malfliet A, et al 2018 Cerebral Blood Flow and Heart Rate Variability in Pain Physician 29357332 https://www.ncbi. 04. Biomedical 04.03 Cardiac Chronic Fatigue Syndrome: A Randomized Cross- 21 (1): E13-E24 nlm.nih.gov/pub Research Function Over Study med/29357332
Bouquet J et al. 2019 Whole blood human transcriptome and virome PLoS One 30897114 https://www.ncbi. 04. Biomedical 04.04 Exercise analysis of ME/CFS patients experiencing post- nlm.nih.gov/pub Research physiology/testin exertional malaise following cardiopulmonary med/30897114 g exercise testing
Lien K et al. 2019 Abnormal blood lactate accumulation during Physiological https://physoc.onl 04. Biomedical 04.04 Exercise repeated exercise testing in myalgic Reports, Volume inelibrary.wiley.c Research physiology/testin encephalomyelitis/chronic fatigue syndrome 7, Issue 11 om/doi/10.14814/ g phy2.14138
Melamed K et al. 2019 Unexplained exertional intolerance associated European https://link.spring 04. Biomedical 04.04 Exercise with impaired systemic oxygen extraction Journal of er.com/article/10. Research physiology/testin Applied 1007%2Fs00421- g Physiology 019-04222- 6?fbclid=IwAR3yt October 2019 PK4rvXbgxPiQxL Nelson MJ et al. 2019 Diagnostic sensitivity of 2-day cardiopulmonary Journal of https://translation 04. Biomedical 04.04 Exercise exercise testing in Myalgic Translational al- Research physiology/testin Encephalomyelitis/Chronic Fatigue Syndrome Medicine volume medicine.biomed g 17, central.com/articl Article number: 8 es/10.1186/s129 0 67 019 1836 0 Polli A, et al. 2019 Relationship Between Exercise-induced Oxidative Clin Ther 30665828 https://www.ncbi. 04. Biomedical 04.04 Exercise Stress Changes and Parasympathetic Activity in nlm.nih.gov/pub Research physiology/testin Chronic Fatigue Syndrome: An Observational med/30665828 g Study in Patients and Healthy Subjects
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McManimen SL 2017 Differences in ME and CFS Symptomology in International 28713856 https://www.ncbi. 04. Biomedical 04.04 Exercise and Jason LA. Patients with Normal and Abnormal Exercise Test Journal of nlm.nih.gov/pmc/ Research physiology/testin Results Neurology and articles/PMC551 g Nerotherapy 4 0614/ (1): 066.
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Kenyon J et al. 2019 A retrospective outcome study of 42 patients with Human https://www.scien 04. Biomedical 04.05 Chronic Fatigue Syndrome, 30 of whom had Microbiome cedirect.com/sci Research Gastrointestinal Irritable Bowel Syndrome. Half were treated with Journal, Volume ence/article/pii/S and microbiome oral approaches, and half were treated with 13, August 2019, 24522317193000 Faecal Microbiome Transplantation 100061 77?fbclid=IwAR3 xQzNGvlwamXb Corbitt M, et al 2018 A Systematic Review of Probiotic Interventions Probiotics and 29464501 https://www.ncbi. 04. Biomedical 04.05 for Gastrointestinal Symptoms and Irritable Bowel Antimicrobial nlm.nih.gov/pub Research Gastrointestinal Syndrome in Chronic Fatigue Syndrome/Myalgic Proteins med/29464501 and microbiome Encephalomyelitis (CFS/ME)
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Du Preez S, et al 2018 A systematic review of enteric dysbiosis in Systematic 30572962 https://www.ncbi. 04. Biomedical 04.05 chronic fatigue syndrome/myalgic Reviews 7 (1): nlm.nih.gov/pub Research Gastrointestinal encephalomyelitis 241 med/30572962 and microbiome
Mandarano AH, 2018 Eukaryotes in the gut microbiota in myalgic Peer Journal 6: 29375937 https://www.ncbi. 04. Biomedical 04.05 et al encephalomyelitis/chronic fatigue syndrome e4282 nlm.nih.gov/pub Research Gastrointestinal med/29375937 and microbiome
Newberry F, et al 2018 Does the microbiome and virome contribute to Clinical Science 29523751 https://www.ncbi. 04. Biomedical 04.05 myalgic encephalomyelitis/chronic fatigue (London) 132 (5): nlm.nih.gov/pub Research Gastrointestinal syndrome? 523-542 med/29523751 and microbiome
Roman P, et al 2018 Are probiotic treatments useful on fibromyalgia Beneficial 29695180 https://www.ncbi. 04. Biomedical 04.05 syndrome or chronic fatigue syndrome patients? Microbes 9 (4): nlm.nih.gov/pub Research Gastrointestinal A systematic review 603-611 med/29695180 and microbiome
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Proal AD and 2018 Myalgic Encephalomyelitis/Chronic Fatigue Frontiers in https://www.fronti 04. Biomedical 04.05 Marshall T Syndrome in the era of the human microbiome: Pediatrics ersin.org/articles/ Research Gastrointestinal persistent pathogens drive chronic symptoms by 10.3389/fped.20 and microbiome interfering with host metabolism, gene expression 18.00373/abstrac and immunity t Wallis, A, et al 2018 Open-label pilot for treatment targeting gut Journal of 29475443 https://www.ncbi. 04. Biomedical 04.05 dysbiosis in myalgic encephalomyelitis/chronic Translational nlm.nih.gov/pub Research Gastrointestinal fatigue syndrome: neuropsychological symptoms Medicine 16 (1): med/29475443 and microbiome and sex comparisons 24
Wang T, et al 2018 Chronic fatigue syndrome patients have PLoS One 13 (9) 30204780 https://www.ncbi. 04. Biomedical 04.05 alterations in their oral microbiome composition nlm.nih.gov/pub Research Gastrointestinal and function med/30204780 and microbiome
Nagy-Szakal D, 2017 Fecal metagenomic profiles in subgroups of BMC Microbiome 28441964 https://www.ncbi. 04. Biomedical 04.05 et al. patients with myalgic encephalomyelitis/chronic 5: 44. nlm.nih.gov/pmc/ Research Gastrointestinal fatigue syndrome articles/PMC540 and microbiome 5467/
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Giloteaux L, et al 2016 Reduced diversity and altered composition of the BMC | 24510231 https://microbiom 04. Biomedical 04.05 gut microbiome in individuals with myalgic Microbiome ejournal.biomedc Research Gastrointestinal encephalomyelitis/chronic fatigue syndrome entral.com/article and microbiome s/10.1186/s4016 8-016-0171-4 Navaneetharaja 2016 A role for the Intestinal Microbiota and Virome in Journal of 27275835 https://www.ncbi. 04. Biomedical 04.05 N, et al Myalgic Encephalomyelitis/Chronic Fatigue Clinical Medicine nlm.nih.gov/pub Research Gastrointestinal Syndrome (ME/CFS)? 5 (6), 55 med/27275835 and microbiome
Bouquet J et al. 2019 Whole blood human transcriptome and virome PLoS One 30897114 https://www.ncbi. 04. Biomedical 04.06 Gene analysis of ME/CFS patients experiencing post- nlm.nih.gov/pub Research expression exertional malaise following cardiopulmonary med/30897114 exercise testing
Kerr JR. 2019 Epstein-Barr Virus Induced Gene-2 Upregulation Front. Pediatr., https://www.fronti 04. Biomedical 04.06 Gene Identifies a Particular Subtype of Chronic Fatigue 13 March 2019 ersin.org/articles/ Research expression Syndrome/Myalgic Encephalomyelitis 10.3389/fped.20 19.00059/full
Raijmakers RPH 2019 A possible role for mitochondrial-derived peptides J Transl Med. 31088495 https://www.ncbi. 04. Biomedical 04.06 Gene et al. humanin and MOTS-c in patients with Q fever nlm.nih.gov/pub Research expression fatigue syndrome and chronic fatigue syndrome med/31088495
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Williams MV et 2019 Epstein-Barr Virus dUTPase Induces Clin Ther. 31040055 https://www.ncbi. 04. Biomedical 04.06 Gene al. Neuroinflammatory Mediators: Implications for nlm.nih.gov/pub Research expression Myalgic Encephalomyelitis/Chronic Fatigue med/31040055 Syndrome
de Vega WC and 2017 The epigenetic landscape of myalgic Epigenomics 9 29043854 https://www.ncbi. 04. Biomedical 04.06 Gene McGowan PO. encephalomyelitis/chronic fatigue syndrome: (11): 1337-1340. nlm.nih.gov/pub Research expression deciphering complex phenotypes. med/29043854
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de Vega WC et 2018 Integration of DNA methylation & health scores Epigenomics 29692205 https://www.ncbi. 04. Biomedical 04.06 Gene al identifies subtypes in myalgic nlm.nih.gov/pub Research expression encephalomyelitis/chronic fatigue syndrome med/29692205
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Trivedi M, et al 2018 Identification of Myalgic PLoS One 13 30036399 https://www.ncbi. 04. Biomedical 04.06 Gene Encephalomyelitis/Chronic Fatigue (7): e0201066 nlm.nih.gov/pub Research expression Syndromeassociated DNA methylation patterns med/30036399
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Pederson M 2019 Chronic Fatigue Syndrome and chronic pain Scand J Pain 31256069 https://www.ncbi. 04. Biomedical 04.07 General conditions - vitally protective systems gone wrong nlm.nih.gov/pub Research reviews med/31256069
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