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List of Publications – Charlotte Ling (690420-4986)

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List of Publications – Charlotte Ling (690420-4986) List of publications – Charlotte Ling (690420-4986) LIST OF PUBLICATIONS – CHARLOTTE LING Total of 103 original publications, 18 invited review papers and 8 book chapters since 1999 H-index: 42; Number of citations ~8.500 Original publications 1. Madhusudhan Bysani, Rasmus Agren, Cajsa Davegårdh, Petr Volkov, Tina Rönn, Per Unneberg, Karl Bacos and Charlotte Ling ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes Scientific Reports, 2019 In Press Impact factor: 6 2. Oliver Kluth, Pascal Gottmann, Markus Jähnert, Stephan Scherneck, Jantje Gerdes, Ulrika Krus, Charlotte Ling, Mandy Stadion and Annette Schürmann Decreased Expression of Cilia-Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Men Cell Reports, 2019, 2019 Mar 12;26(11):3027-3036.e3. Impact factor: 8 3. Paula Walle, Ville Männistö, Vanessa Derenji de Mello, Maija Vaittinen, Alexander Perfilyev, Kati Hanhineva, Charlotte Ling and Jussi Pihlajamäki Liver DNA methylation of FADS2 associates with FADS2 genotype Clin Epigenetics. 2019, In Press. Impact factor: 5.0 4. Cajsa Davegårdh, Elin Hall Wedin, Christa Broholm, Tora Ida Henriksen, Maria Pedersen, Bente Klarlund Pedersen, Camilla Scheele and Charlotte Ling Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes. Stem Cell Research and Therapy, 2019, Jan 15;10(1):26. Impact factor: 5 5. Line Hjort, David Martino, Louise Groth Grunnet, Haroon Naeem, Jovana Maksimovic, Anders Henrik Olsson, Cuilin Zhang, Charlotte Ling, Sjurdur Frodi Olsen, Richard Saffery and Allan Arthur Vaag Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in the children at the age of 9-16 years. JCI Insight, 2018 Sep 6;3(17). pii: 122572. doi: 10.1172/jci.insight.122572. 6. Emma Nilsson, Anna Benrick, Milana Kokosar, Anna Krook, Eva Lindgren, Thomas Källman, Mihaela M Martis, Kurt Højlund, Charlotte Ling and Elisabet Stener-Victorin Transcriptional and epigenetic changes influencing skeletal muscle metabolism in women with polycystic ovary syndrome J Clin Endocrinol Metab. 2018 Dec 1;103(12):4465-4477. Impact factor: 6.5 7. Mahboubeh Daneshpajooh, Lena Eliasson, Karl Bacos and Charlotte Ling MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation Acta Diabetologica, 2018 Dec;55(12):1231-1235. Impact factor: 3.1 8. Pauline Morigny, Marianne Houssier, Aline Mairal, Fadila Benhamed, Etienne Mouisel, Bernard Masri, Emeline Recazens, Pierre-Damien Denechaud, Sylvie Caspar-Bauguil, Geneviève Tavernier, Boris Monge- Rofarello, Sam Virtue, Claire Ghilain, Veronika Sramkova, Laurent Monbrun, Anne Mazars, Madjid Zanoun, Sandra Guilmeau, Valentin Barquissau, Diane Beuzelin, Sophie Bonnel, Marie Marques, Corinne Lefort, Barbara Fielding, Thierry Sulpice, Arne Astrup, Bernard Payrastre, Justine Bertrand-Michel, Emmanuelle Meugnier, Laetitia Ligat, Frédéric Lopez, Hervé Guillou, Charlotte Ling, Cecilia Holm, Remi Rabasa-Lhoret, Wim H. M. Saris, Vladimir Stich, Peter Arner, Mikael Rydén, Cedric Moro, Nathalie Viguerie, Matthew Harms, Stefan Hallén, Antonio Vidal-Puig, Hubert Vidal, Catherine Postic and Dominique Langin Interaction between Hormone-Sensitive Lipase and ChREBP in Fat Cells Controls Insulin Sensitivity Nature Metabolism, In Press 9. García-Calzón S, Perfilyev A, Mello VD, Pihlajamäki J and Ling C. Sex differences in the methylome and transcriptome of the human liver and circulating HDL-cholesterol levels. J Clin Endocrinol Metab. 2018 May 28. doi: 10.1210/jc.2018-00423 Impact factor: 6.5 Citations: 1 10. Milana Kokosar, Anna Benrick, Alexander Perfilyev, Emma Nilsson, Thomas Källman, Claes Ohlsson, Charlotte Ling and Elisabet Stener-Victorin 1 List of publications – Charlotte Ling (690420-4986) A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome. Scientific Reports, 2018 Jan 30;8(1):1878 Impact factor: 6 Citations: 3 11. Elin Hall, Marloes Dekker Nitert, Petr Volkov, Siri Malmgren, Hindrik Mulder, Karl Bacos and Charlotte Ling The effects of high glucose exposure on global gene expression and DNA methylation in human pancreatic islets. Mol Cell Endocrinol. 2017 Nov 26. pii: S0303-7207(17)30605-6. Impact factor: 4.0 Citations: 5 12. You D, Nilsson E, Tenen DE, Lyubetskaya A, Lo JC, Jiang R, Deng J, Dawes BA, Vaag A, Ling C, Rosen ED and Kang S. Dnmt3a is an epigenetic mediator of adipose insulin resistance. Elife. 2017 Nov 1;6. pii: e30766. Impact factor:7.7 Citations: 4 13. Sonia García-Calzón; Alexander Perfilyev; Ville Männistö; Vanessa D. de Mello; Emma Nilsson; Jussi Pihlajamäki and Charlotte Ling Diabetes medication associates with DNA methylation of metformin transporter genes in human liver Clin Epigenetics. 2017 Sep 21;9:102. Impact factor: 5.0 Citations: 6 14. Backe MB, Andersson JL, Bacos K, Christensen DP, Hansen JB, Dorosz JJ, Gajhede M, Dahlby T, Bysani M, Kristensen LH, Ling C, Olsen L, Mandrup-Poulsen T. Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function. Mol Cell Endocrinol. 2017 Jul 4. pii: S0303-7207(17)30355-6. Impact factor: 4.0 Citations: 3 15. Hjort L, Jørgensen SW, Gillberg L, Hall E, Brøns C, Frystyk J, Vaag AA and Ling C. 36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight- dependent manner. Clin Epigenetics. 2017 Apr 21;9:40. Impact factor: 5.0 Citations: 3 16. Cajsa Davegårdh, Christa Broholm, Alexander Perfilyev, Tora Henriksen, Sonia Garcia-Calzon, Lone Peijs, Ninna Schiøler Hansen, Petr Volkov, Rasmus Kjøbsted, Jørgen FP Wojtaszewski, Maria Pedersen, Bente Klarlund Pedersen, Dov B. Ballak, Charles A. Dinarello, Bas Heinhuis, Leo Joosten, Emma Nilsson, Allan Vaag, Camilla Sceele and Charlotte Ling Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects BMC Medicine, 2017, Feb 22;15(1):39. Impact factor: 8.1 Citations: 7 17. Vanessa D. de Mello, Ashok Matte, Alexander Perfilyev, Ville Männistö, Emma Nilsson, Tina Rönn, Pirjo Käkelä, Charlotte Ling* and Jussi Pihlajamäki* *Equal contribution Human liver epigenetic alterations in nonalcoholic steatohepatitis are related to insulin action Epigenetics, 2017, Apr 3;12(4):287-295. Impact factor: 4.8 Citations: 11 18. Ninna Schiøler Hansen, Klaudia Stanislawa Strasko, Line Hjort, Louise Kelstrup, Azadeh Houshmand- Øregaard, Maren Schrölkamp, Heidi Schiøler Schultz, Camilla Scheele, Bente Klarlund Pedersen, Charlotte Ling, Tine Dalsgaard Clausen, Peter Damm, Allan Vaag and Christa Broholm Fetal hyperglycemia changes human preadipocyte function in adult life J Clin Endcrin Metab, 2017, Apr 1;102(4):1141-1150. Impact factor: 6.5 Citations: 7 19. Alexander Perfilyev, Ingrid Dahlman, Linn Gillberg, Fredrik Rosqvist, David Iggman, Petr Volkov, Emma Nilsson, Ulf Risérus and Charlotte Ling Impact of polyunsaturated and saturated fat overfeeding on the DNA methylation pattern in human adipose tissue: a randomized controlled trial The American J of Clinical Nutrition, 2017 Apr;105(4):991-1000. Impact factor: 6.8 Citations: 28 As of March/April 2018, this highly cited paper received enough citations to place it in the top 1% of the academic field of Clinical Medicine based on a highly cited threshold for the field and publication year. 20. Petr Volkov, Karl Bacos, Jones K Ofori, Jonathan L Esguerra, Lena Eliasson, Tina Rönn and Charlotte Ling. Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis. Diabetes. 2017 Jan 4. pii: db160996. Impact factor: 8.6 Citations: 25 21. Bysani M, Perfilyev A, de Mello VD, Rönn T, Nilsson E, Pihlajamäki J and Ling C. Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver. 2 List of publications – Charlotte Ling (690420-4986) Epigenomics. 2017 Feb;9(2):105-122. Impact factor: 4.4 Citations: 7 22. Christian Baumeier, Sophie Saussenthaler, Anne Kammel, Markus Jähnert, Luisa Schlüter, Deike Hesse, Mickaël Canouil, Stephane Lobbens, François Pattou, Emma Nilsson, Jussi Pihlajamäki, Charlotte Ling, Philippe Froguel, Annette Schürmann and Robert W. Schwenk Hepatic DPP4 DNA methylation associates with fatty liver Diabetes, 2017 Jan;66(1):25-35. Impact factor: 8.6 Citations: 10 23. Maria Keller, Lydia Hopp, Xuanshi Liu, Tobias Wohland, Kerstin Rohde; Raffaella Cancello, Matthias Klös, Fabian Eichelmann, Arne Dietrich, Michael R. Schön, Daniel Gärtner, Tobias Lohmann, Miriam Dreßler, Michael Stumvoll, Peter Kovacs, Anna-Maria DiBlasio, Charlotte Ling, Hans Binder, Matthias Blüher and Yvonne Böttcher Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity Molecular Metabolism 2016 Nov 16;6(1):86-100. Impact factor: 5.4 Citations: 14 24. Mahboubeh Daneshpajooh, Karl Bacos, Madhu Bysani, Annika Bagge, Emilia Ottosson Laakso, Petter Vikman, Lena Eliasson, Hindrik Mulder and Charlotte Ling HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells. Diabetologia. 2016 Oct 29. Impact factor: 6.8 Citations: 12 25. Christa Broholm, Anders Henrik Olsson, Alexander Perfilyev, Linn Gilberg, Ninna Schiøler Hansen, Ashfaq Ali, Brynjulf Mortensen, Charlotte Ling, and Allan Vaag Human adipogenesis is associated with alterations in the
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