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2019, Vol. 15, Number 2, 85–138

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2019, Vol. 15, Number 2, 85–138 Oncology in Clinical Practice 2019, Vol. 15, Number 2, 85–138 Oncology in Clinical Practice 2019, Vol. 2019, Vol. 15, Number 2 ISSN 2450–1654 Beata Hryciuk, Bartosz Szymanowski, Michał Bieńkowski, Adrian Perdyan, Aleksandra Korwat, Kamil Winnik, Barbara Radecka, Jolanta Żok, Natalia Cichowska, Katarzyna Sosińska-Mielcarek, Rafał Pęksa, Renata Duchnowska Consistency in biomarkers expression between matched tissue microarray cores from primary gallblader and ovarian cancers Marcin Kaczor, Rafał Wójcik, Joanna Połowinczak-Przybyłek, Piotr Potemski Critical appraisal of clinical trials in oncology — part I Monika Konopka-Filippow, Ewa Sierko, Marek Z. Wojtukiewicz Benefits and difficulties during brain radiotherapy planning with hippocampus sparing Ewa Cedrych, Ida Cedrych Neratinib in adjuvant treatment of patients with HER2-positive breast cancer — less is more? Katarzyna Kozak, Piotr Rutkowski Why do we need a new BRAF-MEK inhibitor combination in melanoma? Małgorzata Flis, Paweł Krawczyk, Izabella Drogoń, Katarzyna Kurek, Robert Kieszko, Janusz Milanowski The effectiveness of chemotherapy in small cell lung cancer patients with BRCA2 gene mutation and Schwartz-Bartter syndrome Piotr Tomczak, Zuzanna Synowiec Nivolumab in the treatment of advanced renal cell carcinoma Aneta Lebiedzińska, Dawid Sigorski, Maciej Michalak, Zygmunt Kozielec, Anna Doboszyńska, Dariusz Zadrożny, Paweł Różanowski Complete pathological remission after palliative therapy with sorafenib in hepatocellular carcinoma — case report Kamila Kaźmierczak, Joanna Kufel-Grabowska, Tomasz Kozłowski, Błażej Nowakowski When to say “no” to a patient with an ovarian tumour and in poor general condition? Maciej Kawecki Current literature review ONCOLOGY IN CLINICAL PRACTICE Official Journal of the Polish Society of Clinical Oncology https://journals.viamedica.pl/oncology_in_clinical_practice Editor-in-Chief dr med. Aleksandra Łacko prof. dr hab. med. Maciej Krzakowski prof. Ruggero De Maria (Rome, Italy) dr hab. med. Radosław Mądry Deputy Editors dr med. Janusz Meder prof. dr hab. med. Andrzej Kawecki dr hab. med. Sergiusz Nawrocki prof. dr hab. med. Piotr Potemski prof. dr hab. med. Włodzimierz Olszewski prof. dr hab. med. Piotr Rutkowski prof. dr hab. med. Maria Podolak-Dawidziak prof. dr hab. med. Krzysztof Składowski dr med. Barbara Radecka prof. dr hab. med. Piotr Wysocki prof. dr hab. med. Tadeusz Robak prof. dr hab. med. Kazimierz Roszkowski Scientific Board prof. dr hab. med. Piotr Rutkowski dr Edita Baltruskeviciene (Vilnius, Lithuania) dr hab. med. Ewa Sierko prof. Tomasz M. Beer (Portland, USA) dr Ryszard Szydło (London, UK) dr med. Joanna Didkowska prof. dr hab. med. Jerzy Walecki dr hab. med. Renata Duchnowska dr med. Beata Jagielska prof. dr hab. med. Jan Walewski dr med. Jerzy Jarosz prof. dr hab. med. Krzysztof Warzocha prof. dr hab. med. Jacek Jassem prof. dr hab. med. Marek Wojtukiewicz prof. dr hab. med. Arkadiusz Jeziorski dr Agnieszka Wozniak (Leuven, Belgium) prof. dr hab. med. Jan Kornafel prof. Christoph Zielinski (Vienna, Austria) prof. dr hab. med. Jan Kulpa prof. dr hab. med. Radzisław Kordek Managing Editor dr hab. med. Maria Litwiniuk Izabela Siemaszko Opinions presented in the articles do not necessarily represent the opinions of the Editors Oncology in Clinical Practice (ISSN 2450–1654) is published six times a year by VM Media sp. z o.o. VM Group sp.k. ul. Świętokrzyska 73, 80–180 Gdańsk, Poland Phone: (+48 58) 320 94 94, fax: (+48 58) 320 94 60 e-mail: [email protected], http://www.viamedica.pl, wap.viamedica.pl Editorial Address Klinika Nowotworów Płuca i Klatki Piersiowej Centrum Onkologii — Instytut im. Marii Skłodowskiej-Curie ul. Roentgena 5, 02–781 Warszawa, Poland Phone: (+48 22) 546 21 69 e-mail: [email protected] Advertising For details on media opportunities within this journal please contact the advertising sales department, ul. Świętokrzyska 73, 80–180 Gdańsk, Poland, phone: (+48 58) 326 78 20; e-mail: [email protected] The Editors accept no responsibility for the advertisement contents. All rights reserved, including translation into foreign languages. No part of this periodical, either text or illustration, may be used in any form whatsoever. It is particularly forbidden for any part of this material to be copied or translated into a mechanical or electronic language and also to be recorded in whatever form, stored in any kind of retrieval system or transmitted, whether in an electronic or mechanical form or with the aid of photocopying, microfilm, recording, scanning or in any other form, without the prior written permission of the publisher. The rights of the publisher are protected by national copyright laws and by international conventions, and their violation will be punishable by penal sanctions. Legal note: http://czasopisma.viamedica.pl/owpk/about/legalNote Indexed in Index Copernicus (ICV 2018 = 84.45), Ulrich’s Periodicals Directory and CAS. According to the statement of the Polish Ministry of Science and Higher Education publication in the journal has been awarded with 20 points. Editorial policies and author guidelines are published on journal website: http://journals.viamedica.pl/oncology_in_clinical_practice The journal “Oncology in Clinical Practice” is financed under Contract No. 790/P-DUNdem/2019 by the funds of the Minister of Science and Higher Education for the science promotion activities. Copyright © 2019 Via Medica Professor Krzysztof Krzemieniecki Award for the best case report accepted for publication Case Report Contest Policies This policy defines the scope, requirements and regulations regarding The Krzysztof Krzemieniecki Award for the best case report published in “Oncology in Clinical Practice” (OCP) Third Edition. 1. The aim of the contest is to encourage submission of quality case reports related to oncological practice and to promote them in the scientific deliberations. 2. All respective manuscripts submitted to OCP between June 1st, 2018 and May 31st, 2019 and accepted for publication will qualify. 3. Manuscripts should be prepared in line with Authors’ guidelines and should be submitted only through the manuscript system available at Journal’s website: https://journals.viamedica.pl/oncology_in_clinical_practice 4. All submitted manuscripts will be evaluated during the peer review process and authors will be informed about their qualification for publication in OCP. Accepted papers will be evaluated by the Contest Committee based upon fulfillment of the Contest criteria as well as practical significance, originality, applicability and addressing of current/critical concerns. 5. The first author of the winning paper will be eligible for a prize of gross 1000,00 Euro gross (one thousand euro). 6. Results will be announced during the XXII National Congress of The Polish Society of Clinical Oncology which will take place between August 29th and 31st, 2019 and subsequently at the Journal website. 7. Winner will be notified via email. 8. Contest Committee may exclude a paper from participation in case of potential conflict of interest or ask submitting author for adequate clarifications. 9. The Sponsor at any stage and in any respect, will not participate in the evaluation of entries and selection of a winning paper. 10. The award amount shall be paid based on the copyright transfer agreement to the paper. 11. These Regulations are the sole and exclusive document defining the principles and conditions for the Contest. In all matters not regulated, decisions are made by The Organizer. Contest Organizer: VM Media sp. z o.o. VM Group sp. k., seated at 73 Swietokrzyska Street, 80-180 Gdansk, Poland (Register of Entrepreneurs kept by the District Court for Gdansk, Commercial Division VII of the National Court Register under KRS No 0000266430, VAT Reg. No PL 583-28-39-187). Patronage ONCOLOGY IN CLINICAL PRACTICE Official Journal of the Polish Society of Clinical Oncology https://journals.viamedica.pl/oncology_in_clinical_practice 2019, Vol. 15, Number 2 ORIGINAL ARTICLE Consistency in biomarkers expression between matched tissue microarray cores from primary gallblader and ovarian cancers Beata Hryciuk, Bartosz Szymanowski, Michał Bieńkowski, Adrian Perdyan, Aleksandra Korwat, Kamil Winnik, Barbara Radecka, Jolanta Żok, Natalia Cichowska, Katarzyna Sosińska-Mielcarek, Rafał Pęksa, Renata Duchnowska ......................................................................................................................... 85 REVIEW ARTICLES Critical appraisal of clinical trials in oncology — part I Marcin Kaczor, Rafał Wójcik, Joanna Połowinczak-Przybyłek, Piotr Potemski .................................................... 89 Benefits and difficulties during brain radiotherapy planning with hippocampus sparing Monika Konopka-Filippow, Ewa Sierko, Marek Z. Wojtukiewicz ........................................................................ 104 Neratinib in adjuvant treatment of patients with HER2-positive breast cancer — less is more? Ewa Cedrych, Ida Cedrych .................................................................................................................................. 111 Why do we need a new BRAF-MEK inhibitor combination in melanoma? Katarzyna Kozak, Piotr Rutkowski ....................................................................................................................... 115 CASE REPORTS The effectiveness of chemotherapy in small cell lung cancer patients with BRCA2 gene mutation and Schwartz-Bartter syndrome Małgorzata Flis, Paweł Krawczyk, Izabella
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