DOCSLIB.ORG

Download the Report (PDF, 6.2MB)

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Download the Report (PDF, 6.2MB) YEAR IN REVIEW Institute for Molecular Bioscience 2016 Annual Report CONTENTS ABOUT 4 2016 snapshot 6 Message from the Vice-Chancellor and President 8 Message from the Director 10 2016 highlights 12 DISCOVERY 14 Feature: Shining a diagnostic light on rare diseases 16 Feature: Scientists developing new diagnostic techniques in the fight against superbugs 18 Feature: At the centre of it all, could understanding inflammation provide the silver bullet? 19 Feature: The mysterious language of pain and the fight to switch it off 20 Feature: Growing new organs – science fiction or science future? 22 Grants and fellowships 24 2016 award highlights 26 LEARNING 28 Research training 30 Research Higher Degree students 32 2016 RHD conferrals 34 ENGAGEMENT 36 Research commercialisation 38 Community engagement 40 Global collaborations 42 OUR PEOPLE 44 IMB boards and committees 46 Our people 47 Joint appointments and affiliates 50 Science ambassadors 51 SUPPORTING INFORMATION 52 Financial statement 54 Research grants 55 Research facilities 61 Publications 64 GIVING 66 Discoveries inspired by life 66 THANK YOU TO OUR SUPPORTERS 67 2 IMB YEAR IN REVIEW IMB YEAR IN REVIEW 3 ABOUT The University of Queensland’s Our research is framed through MISSION RESEARCH CENTRES STRATEGIC PRIORITIES Institute for Molecular six research centres focusing on superbug infection, pain, heart disease, Our mission is to advance scientific Centre for Inflammation Discovery excellence Bioscience (IMB) is a global inflammation, solar biotechnology and the knowledge and deliver new health and and Disease Research Translational impacts leader in multidisciplinary life industry applications from the best in interplay of genomics and disease. We Centre for Pain Research Learning sciences research. IMB brings also undertake research in cancer, the life sciences research. Centre for Superbug Solutions Leadership and engagement environment and agricultural solutions. together 500 researchers, Centre for Solar Biotechnology VISION Equity and sustainability students and support staff IMB’s combination of genomics, UQ Project Three Billion biostatistical, biological, from across the globe, using Our vision is to be a global leader in the UQ Centre for Cardiac and pharmacological and chemical life sciences research for discovery and application of molecular Vascular Biology disease discovery, application researchers means the Institute can life sciences research. take life science discoveries from the and sustainable futures. genome to drug design and application – for health, disease and for the sustainable solutions for our cities, fuels and foods. With 66 patents and 11 spin- outs to our name, UQ’s IMB is driven to SHARE IN OUR DISCOVERIES using life science research for discovery, Subscribe to our IMB news and event updates invention and application. imb.uq.edu.au/subscribe JOIN OUR SOCIAL COMMUNITIES Twitter.com/IMBatUQ Facebook.com/InstituteforMolecularBioscience Youtube.com/IMBatUQ THE IMPACT OF OUR RESEARCH SPANS THE AREAS OF Agriculture Cancer Solar Diabetes Infection Pain biotechnology and obesity Heart and Inflammation Brain injury Rare and Superbugs cardiovascular and disease complex diseases diseases 4 IMB YEAR IN REVIEW IMB YEAR IN REVIEW 5 2016 SNAPSHOT research centres 5 total research income 4 38 patent families managed Centre for Pain Research $30.1M competitive funding 7 4 agricultural/industrial biotechnology 20.1 30.1 21 Centre for Inflammation and Disease Research $20.1M operating 7 diagnostic/devices Centre for Superbug Solutions $5M philanthropy, commercialisation, 6 6 drug discovery tools UQ Centre for Cardiac and Vascular Biology other income and recoveries 21 therapeutics Centre for Solar Biotechnology UQ Project Three Billion $ world-class research facilities 10M 9 8 active Australian Research Council Linkage Projects $ with industry partners awarded from the 2.3M National Health and Medical Research Council grant awarded 500 from the 60 new partnerships researchers, postgrad students & support staff formed in 2016 Honours, undergraduate, $ occupational trainee and 4.5M coursework masters students hosted at IMB > % awarded 5 to establish the new ACRF 7 from the Cancer Ultrastructure and of IMB's publications include 121 % Australian Research Council Function Facility new patents filed industry collaborations active research higher degree students 100 honours students 364 achieved first class honours publications 4 Thomson Reuters Highly inflammatory disease Cited Researchers 41 research research higher degree secured up to a students graduated $22M over 1000 collaborations in global investment 40 Host of one of the largest biotech 7 Series A investments for high-impact scientific Fellows of the Australian the Queensland Emory intellectual property originating 57 publications Academy of Science Drug Discovery Initiative (QEDDI) from an Australian university countries 6 IMB YEAR IN REVIEW IMB YEAR IN REVIEW 7 In 2016 the University advanced by In 2016, their innovation delivered By partnering with them in 2016, 22 places in the Academic Ranking of outcomes of global significance: IMB has: MESSAGE FROM THE World Universities, to rank 55th globally They started work on a new Created an organic insecticide that is and second in Australia. UQ is the only generation of drugs to be grown in protecting cotton crops and saving Australian university to rank in the top VICE-CHANCELLOR AND plants; bees; 20 for life sciences – an impressive achievement. As our largest institute, They identified a treatment target for Uncovered compounds in tarantula the Institute for Molecular Bioscience aggressive forms of breast cancer; venom that are a potential treatment plays a significant role in UQ’s success. They grew beating human heart for sheep parasites, a major cost for tissue from stem cells that will one the international sheep industry; However, research excellence in itself day be used to regenerate the hearts Made clean fuel from green algae; PRESIDENT is insufficient for translating discoveries of patients with heart disease; into meaningful outcomes with Attracted $22 million in global They made a discovery that investment to develop new treatments A clear measure of success in science is the impact that discoveries have on the world and the substantial impact. Such translation also could lead to a new treatment for inflammatory diseases such as lives of its people. The University of Queensland (UQ) has earned an international reputation for requires engagement with exceptional partners in industry, government and for Parkinson’s disease, and has Parkinson’s and asthma; excellence in research, as signified by our performance in international rankings. the community, and with researchers potential applications for nearly 50 Developed environmentally friendly who are connected across disciplines. other disorders; cane toad traps to catch tadpoles They progressed the development of before they can reproduce; and This is why the Institute for Molecular new drugs that target the underlying Developed a model to more Bioscience is multidisciplinary. It brings cause of diabetes; accurately forecast CO2 emissions. together researchers with different They identified four new classes of perspectives and expertise, who share The discoveries made at the Institute compounds that act against drug- one goal: high quality Discovery and and their applications attest to the resistant tuberculosis; Translation. They exchange ideas power of a multi-disciplinary approach across fields and challenge each other They identified interactions between to creating impact in Life Sciences to look at things differently, to ask new immune system pathways that could research. questions, and to create new areas of improve treatment of autoimmune I congratulate Director Professor science. They are working with partners and inflammatory diseases; Brandon Wainwright and the Institute on local problems with global impact, They discovered a protein in spider for Molecular Bioscience team. Their forging research discoveries with broad venom that binds to and inhibits pain curiosity in 2016 made an impressive application to combatting disease and receptors, uncovering a promising contribution to advancing human other global challenges. future treatment for chronic pain; and knowledge, to creating change and to They found a diagnosis for some of solving some of the world’s greatest the many Australians suffering from challenges. unresolved rare diseases. Professor Peter Høj Industry, international collaborators and Vice-Chancellor and President funding bodies alike are recognising the The University of Queensland Institute’s ability to translate discoveries into solutions. 8 IMB YEAR IN REVIEW IMB YEAR IN REVIEW 9 MESSAGE FROM THE DIRECTOR Improving quality of life is Here are some examples: IMB secured funding, through an IMB INNOVATORS MAKING DISCOVERY DRIVES US FORWARD Australian Research Council Linkage AN IMPACT the goal of research at IMB, We created the world’s first molecule Solutions to some of life’s most Infrastructure, Equipment and from discovering new ways to bank, crowdsourcing antibiotic One of the greatest signatures of the complicated problems lie in discovering Facilities grant and an Australian compounds from across the globe, enduring quality of our achievements is the essence of life itself. Disease diagnose and treat disease to Cancer Research Foundation to find new antibiotics to fight drug- our staff and research training students. discovery epitomises the mission of the
Load more

Recommended publications
  • PMC6433737.Pdf
    Briefings in Bioinformatics, 20(2), 2019, 384–389 doi: 10.1093/bib/bbx071 Advance Access Publication Date: 30 June 2017 Paper Establishing a distributed national research infrastructure providing bioinformatics support to life science researchers in Australia Maria Victoria Schneider, Philippa C. Griffin, Sonika Tyagi, Madison Flannery, Saravanan Dayalan, Simon Gladman, Maria V. Schneider is the Deputy Director of EMBL Australia Bioinformatics Resource (EMBL-ABR) and Associate Professor at the University of Melbourne, Australia. She has a keen interest in data-driven science and open science and best practice in data life cycle, FAIR data, tools and bioinformatics training. Philippa C. Griffin is a Bioinformatician/Research Fellow at EMBL-ABR: Melbourne Bioinformatics Node, University of Melbourne, Australia. She uses bio- informatics approaches to tackle questions around species ecology, evolution and climate response. Sonika Tyagi is the Bioinformatics Supervisor at the Australian Genome Research Facility Ltd, in Melbourne. She is also the Head of the EMBL-ABR: AGRF Node. She develops bioinformatics tools and applications using machine learning, data mining and statistical approaches. She has a keen interest in open source and bioinformatics training. She is the champion for EMBL-ABR Key Area Training Coordination. Madison Flannery was a developer at the EMBL-ABR: MelBioinf Node supporting EMBL-ABR Hub with ToolsAU and STM. Saravanan Dayalan is the Lead Scientist (Bioinformatics and Biostatistics) at Metabolomics Australia, the University of Melbourne. He is part of EMBL- ABR: MA Node and currently the champion for EMBL-ABR Key Area Standards Coordination. He is interested in large-scale bioinformatics solutions, such geographically distributed LIMS and database systems, biostatistical methods and big data.
    [Show full text]
  • Gabrielli318947-Published.Pdf
    Multiple interaction nodes define the postreplication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load Author Pavey, S, Pinder, A, Fernando, W, D’Arcy, N, Matigian, N, Skalamera, D, Lê Cao, KA, Loo-Oey, D, Hill, MM, Stark, M, Kimlin, M, Burgess, A, Cloonan, N, Sturm, RA, Gabrielli, B Published 2019 Journal Title Molecular Oncology DOI https://doi.org/10.1002/1878-0261.12601 Copyright Statement © 2019 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Downloaded from http://hdl.handle.net/10072/390173 Griffith Research Online https://research-repository.griffith.edu.au Multiple interaction nodes define the postreplication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load Sandra Pavey1, Alex Pinder1, Winnie Fernando2, Nicholas D’Arcy2, Nicholas Matigian1,3, Dubravka Skalamera1,2, Kim-Anh Le^ Cao1*, Dorothy Loo-Oey1, Michelle M. Hill1,4 , Mitchell Stark1 , Michael Kimlin5, Andrew Burgess6, Nicole Cloonan4†, Richard A. Sturm1 and Brian Gabrielli1,2 1 Diamantina Institute, TRI, The University of Queensland, Woolloongabba, QLD, Australia 2 Mater Research, TRI, The University of Queensland, Woolloongabba, QLD, Australia 3 QFAB Bioinformatics, The University of Queensland, Brisbane, QLD, Australia 4 QIMR Berghofer Medical Research Institute, Herston, QLD, Australia 5 University of the Sunshine Coast, Sippy Downs, QLD, Australia 6 ANZAC Research Institute, Concord, NSW, Australia Keywords Ultraviolet radiation-induced DNA mutations are a primary environmental DNA repair; G2 phase checkpoint; MASTL; driver of melanoma.
    [Show full text]
  • Imb 2014 Winterinin Schoolin Mathematicalmathematicalmathematical&& Computationalcomputationalin & Computational Biologybiology Biology
    20142014 WINTERWINTER2014 WINTERSCHOOLSCHOOL SCHOOL IMB 2014 WINTERININ SCHOOLIN MATHEMATICALMATHEMATICALMATHEMATICAL&& COMPUTATIONALCOMPUTATIONALIN & COMPUTATIONAL BIOLOGYBIOLOGY BIOLOGY MATHEMATICAL & COMPUTATIONAL BIOLOGY in in of Centre ARC Bioinformatics Excellence 7-117-11 JulyJuly 201420147-11 July 2014 7-11 July 2014 Hosted by: Hosted Auditorium AuditoriumAuditoriumAuditorium Queensland Bioscience Precinct QueenslandQueenslandQueensland Bioscience BioscienceBioscience Precinct PrecinctPrecinct TheTheThe UniversityUniversity UniversityThe University ofof QueenslandQueensland of Queensland Brisbane,Brisbane,Brisbane, AustraliaAustraliaBrisbane, Australia PROGRAM PROGRAMPROGRAMPROGRAMPROGRAM Brisbane, Australia Brisbane, The University of Queensland of University The Queensland Bioscience Precinct Bioscience Hosted by: Queensland Auditorium HostedHosted by:by: Hosted by: 7-11 July 2014 July 7-11 ARCARC CentreCentre ofof ExcellenceExcellenceARC Centreinin BioinformaticsBioinformatics of Excellence in Bioinformatics & COMPUTATIONAL BIOLOGY COMPUTATIONAL & MATHEMATICAL IN IN IMIMBIMBB IMB 2014 WINTER SCHOOL WINTER 2014 2014 Winter School in Mathematical and Computational Biology 7-11 July 2014 http://bioinformatics.org.au/ws14 Queensland Bioscience Precinct (Building #80) The University of Queensland Brisbane, Australia Monday 7 July 2014 NEXT GENERATION SEQUENCING & BIOINFORMATICS 8:15 a.m. REGISTRATION OPENS 9:00 a.m. Welcome and introduction Dr Nicholas Hamilton Institute for Molecular Bioscience The University of Queensland 09:05 a.m. Next-generation sequencing: an overview of technologies and applications Dr Ken McGrath Australian Genome Research Facility Ltd (AGRF) Brisbane Node (The University of Queensland) 09:45 a.m. NGS mapping, errors and quality control Dr Felicity Newell The University of Queensland Diamantina Institute 10:30 a.m. Morning Tea 11:00 a.m. Defensive NGS informatics – what can go wrong and how do you know when to throw in the towel? Mr John Pearson QIMR Berghofer Medical Research Institute 11:45 a.m.
    [Show full text]
  • Queensland Brain Institute 2014 Annual Report
    Queensland Brain Institute 2014 Annual Report Queensland Brain Institute 2014 Annual Report Cover Image: Garden of Neurons by Gonzalo Almarza We are studying different populations of neurons in the cortex. In this image, subplate neurons (green) extend their processes towards the pial surface during early cortical development. These neurons project through the emerging cortical plate (in red), arborising in the marginal zone (in blue). Queensland Brain Institute Annual Report 2014 UQ Vice-Chancellor and President’s Report ........................1 QBI Director’s Report ...........................................2 Discovery 4 Genome analysis reveals schizophrenia’s secrets ...................6 Halting the damaging effects of stroke ............................8 Revealing the complexity of wiring the brain. .10 Redefining how we plan movement in the brain ....................12 Controlling fear may be possible by controlling DNA ................14 Research 16 Anggono Laboratory ........17 Goodhill Laboratory .........27 Mowry Laboratory ..........37 Srinivasan Laboratory .......43 Bartlett Laboratory ..........18 Götz Laboratory ............28 Osborne Laboratory .........38 van Swinderen Laboratory ...44 Bredy Laboratory ...........19 Hilliard Laboratory ..........29 Piper Laboratory ............39 Visscher Laboratory .........45 Burne Laboratory ...........20 Jiang Laboratory ............30 Reinhard Laboratory ........40 Williams Laboratory .........46 Cheung Laboratory .........21 Lynch Laboratory ...........31 Richards Laboratory .........41
    [Show full text]
  • Victorian Life Sciences Computation Initiative
    REPORT TO VLSCI 4 SEPTEMBER 2015 VICTORIAN LIFE SCIENCES COMPUTATION INITIATIVE FIVE YEAR REVIEW LAPSING PROGRAM REPORT ACIL ALLEN CONSULTING PTY LTD ABN 68 102 652 148 61 WAKEFIELD STREET ADELAIDE SA 5000 AUSTRALIA T +61 (0)412 089 043 LEVEL FIFTEEN 127 CREEK STREET BRISBANE QLD 4000 AUSTRALIA T+61 7 3009 8700 F+61 7 3009 8799 LEVEL TWO 33 AINSLIE PLACE CANBERRA ACT 2600 AUSTRALIA T+61 2 6103 8200 F+61 2 6103 8233 LEVEL NINE 60 COLLINS STREET MELBOURNE VIC 3000 AUSTRALIA T+61 3 8650 6000 F+61 3 9654 6363 LEVEL ONE 50 PITT STREET SYDNEY NSW 2000 AUSTRALIA T+61 2 8272 5100 F+61 2 9247 2455 LEVEL TWELVE, BGC CENTRE 28 THE ESPLANADE PERTH WA 6000 AUSTRALIA T+61 8 9449 9600 F+61 8 9322 3955 ACILALLEN.COM.AU SUGGESTED CITATION FOR THIS REPORT ACIL ALLEN CONSULTING, VLSCI FIVE YEAR REVIEW LAPSING PROGRAM REPORT, SEPTEMBER 2015. © ACIL ALLEN CONSULTING 2015 EXECUTIVE SUMMARY The Victorian Life Sciences Computation Initiative (VLSCI) is a research infrastructure funding initiative that provides supercomputing facilities and resources to support and strengthen life sciences research in Victoria. ACIL Allen Consulting was commissioned to prepare a report on the Initiative’s benefits, the operations, mechanisms and processes used to deliver those benefits, and to assess the Initiative’s value for money for the Victorian Government, industry and the research community. The report was developed in accordance with the Victorian Government’s guidelines for the evaluation of lapsing programs. The key findings from our evaluation are listed below.
    [Show full text]
  • Michel Foucault Ronald C Kessler Graham Colditz Sigmund Freud
    ANK RESEARCHER ORGANIZATION H INDEX CITATIONS 1 Michel Foucault Collège de France 296 1026230 2 Ronald C Kessler Harvard University 289 392494 3 Graham Colditz Washington University in St Louis 288 316548 4 Sigmund Freud University of Vienna 284 552109 Brigham and Women's Hospital 5 284 332728 JoAnn E Manson Harvard Medical School 6 Shizuo Akira Osaka University 276 362588 Centre de Sociologie Européenne; 7 274 771039 Pierre Bourdieu Collège de France Massachusetts Institute of Technology 8 273 308874 Robert Langer MIT 9 Eric Lander Broad Institute Harvard MIT 272 454569 10 Bert Vogelstein Johns Hopkins University 270 410260 Brigham and Women's Hospital 11 267 363862 Eugene Braunwald Harvard Medical School Ecole Polytechnique Fédérale de 12 264 364838 Michael Graetzel Lausanne 13 Frank B Hu Harvard University 256 307111 14 Yi Hwa Liu Yale University 255 332019 15 M A Caligiuri City of Hope National Medical Center 253 345173 16 Gordon Guyatt McMaster University 252 284725 17 Salim Yusuf McMaster University 250 357419 18 Michael Karin University of California San Diego 250 273000 Yale University; Howard Hughes 19 244 221895 Richard A Flavell Medical Institute 20 T W Robbins University of Cambridge 239 180615 21 Zhong Lin Wang Georgia Institute of Technology 238 234085 22 Martín Heidegger Universität Freiburg 234 335652 23 Paul M Ridker Harvard Medical School 234 318801 24 Daniel Levy National Institutes of Health NIH 232 286694 25 Guido Kroemer INSERM 231 240372 26 Steven A Rosenberg National Institutes of Health NIH 231 224154 Max Planck
    [Show full text]
  • ABACBS 2020 Virtual Conference Conference Program
    ABACBS 2020 Virtual Conference Conference Program Conference committee members: Eduardo Eyras (Conference Convener) Aaron Darling Jimmy Breen Gavin Huttley Jean Wen Priyanka Surana Susan Wagner Melanie Smith Attila Horvath Fabio Zanini Sonika Tyagi Annette McGrath Ignatius Pang ABACBS 2020 Virtual Conference is Proudly Supported by Gold Conference Sponsor Silver Conference Sponsor Bronze Conference Sponsor ABACBS Day 1 (Tuesday 24th November) Time (AEDT) Parallel Session 1: Plant Genomics Parallel Session 2: Metagenomics (Session Chair: Jen Taylor) (Session Chair: Aaron Darling) Canberra Cafe Remo Link ​ Invited Speaker: Sue Rhee Invited Speaker: Ami Bhatt 12:30 Challenges and Opportunities​ for Bioinformatics Microproteins, Mobile​ Genetic elements and and Computational Biology in Plant Science Strain-level resolution in the microbiome – a path to precision medicine Session Talk #38 Session Talk #35 12:50 Stephanie Chen Feargal Ryan Unsupervised orthologous gene tree enrichment Intrapartum or Direct Antibiotic Exposure in Early for cost-effective phylogenomic analysis and a test Life Significantly Alters the Infant Microbiota and case on waratahs (Telopea spp.) Whole-blood Transcriptional Responses to Immunisation Session Talk #112 Session Talk #127 13:00 Charlotte Francois Luis Pedro Coelho New insights into plant-microbe interactions The AMPSphere: antimicrobial peptides (AMPs) in through Quantitative Trait Locus (QTL) mapping the global microbiome Session Talk #110 Session Talk #8 13:10 Chelsea Matthews Daniela Gaio Assessing PacBio
    [Show full text]
  • ANNUAL REPORT 24 February 2021 Acknowledgement of Country We Acknowledge the Traditional Owners and Their Custodianship of the Lands on Which Our University Stands
    The University of Queensland 2020 ANNUAL REPORT 24 February 2021 Acknowledgement of Country We acknowledge the Traditional Owners and their custodianship of the lands on which our University stands. We pay our respects to their Ancestors and descendants, who The Honourable Grace Grace MP continue cultural and spiritual connections Minister for Education, Minister for Industrial Relations to Country. We recognise their valuable and Minister for Racing contributions to Australian and global society. PO Box 15033 CITY EAST QLD 4002 Dear Minister I am pleased to submit for presentation to the Parliament the Annual Report 2020 and financial statements for The University of Queensland. I certify that this Annual Report complies with: – the prescribed requirements of the Financial Accountability Act 2009 and the Financial and Performance Management Standard 2019 – the detailed requirements set out in the Annual report requirements for Queensland Government agencies, July 2020. A checklist outlining the annual reporting requirements can be found at Public availability note about.uq.edu.au/annual-reports. This report, as at 31 December 2020, was produced by Marketing and Communication, The University of Queensland, Brisbane, Queensland 4072 Australia; and is available online at about.uq.edu.au/annual-reports, or by calling +61 7 3365 2479 or emailing [email protected]. Yours sincerely The following information is available online at about.uq.edu.au/annual-reports and on the Queensland Government Open Data website at data.qld.gov.au: – Consultancies – Overseas travel. Interpreter service statement The University of Queensland (UQ) is committed to providing accessible services to people from all culturally and Peter N Varghese AO linguistically diverse backgrounds.
    [Show full text]
  • 2009-10 Contents
    ANNUAL REPORT 2009-10 CONTENTS ABOUT QIMR 1 RESEARCH DIVISIONS 14 QIMR at a glance 2 Cancer and Cell Biology 16 Research highlights 4 Genetics and Population Health 27 Awards and achievements 6 Immunology 43 Chairman’s report 8 Infectious Diseases 56 Members of Council 9 Mental Health 72 Director’s report 11 Joint Research 74 Cover: Tissue culture plate courtesy of phototonyphillips.com | Inside Cover: Aedan Roberts, PhD student, Familial Cancer Laboratory ABOUT US OUR QIMR is one of Australia’s largest and most successful PHILOSOPHY medical research institutes. Our researchers are investigating the genetic and environmental causes QIMR supports scientists who perform world-class of more than 40 diseases as well as developing new medical research aimed at improving the health and diagnostics, better treatments and prevention strategies. well-being of all people. The Institute’s diverse research program extends from tropical diseases to cancers to Indigenous health, mental health, obesity, HIV and asthma. OUR VISION OUR LOGO To be a world renowned medical research institution. The QIMR logo is comprised of superimposed benzene rings which symbolise one of the fundamental molecular arrangements of the chemicals which make up living things. OUR MISSION Director – Professor Michael Good AO Deputy Director – Professor Adèle Green AC Better health through medical research. Patron – Her Excellency Ms Penelope Wensley AO www.qimr.edu.au | [email protected] CORPORATE DIVISION 78 Patents 93 Trust report 83 Offi cial Committees 94 Members of Trust 84 Publications 96 POSTGRADUATE TRAINING 85 Lectures 108 Completed students 87 Staff 117 Student awards 88 Students 124 AWARDS 89 Visiting Scientists 125 Grants and funding 91 Organisational Structure 128 QIMR Annual Report 2009/10 1 100713_QIMR_AR10_FINAL.indd 1 22/09/10 10:04 AM QIMR AT A GLANCE Supporting scientists who perform world-class medical research aimed at improving the health and well-being of all people.
    [Show full text]
  • A Parsimonious Model for Mass-Univariate Vertex-Wise Analysis
    A parsimonious model for mass-univariate vertex-wise analysis Baptiste Couvy-Duchesne, Futao Zhang, Kathryn Kemper, Julia Sidorenko, Naomi Wray, Peter Visscher, Olivier Colliot, Jian Yang To cite this version: Baptiste Couvy-Duchesne, Futao Zhang, Kathryn Kemper, Julia Sidorenko, Naomi Wray, et al.. A parsimonious model for mass-univariate vertex-wise analysis. 2021. hal-03118366 HAL Id: hal-03118366 https://hal.archives-ouvertes.fr/hal-03118366 Preprint submitted on 22 Jan 2021 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. A parsimonious model for mass-univariate vertex-wise analysis Baptiste Couvy-Duchesne1,2, Futao Zhang1, Kathryn E. Kemper1, Julia Sidorenko1, Naomi R. Wray1,*, Peter M. Visscher1,*, Olivier Colliot2,*, Jian Yang1,3,4,* 1 Institute for Molecular Bioscience, the University of Queensland, St Lucia, QLD, Australia; 2 Paris Brain Institute (ICM), Inserm U 1127, CNRS UMR 7225, Sorbonne University, Inria, Aramis project-team, F-75013, Paris, France; 3 School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; 4 Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China * These authors contributed equally. Correspondence: BCD ([email protected]), JY ([email protected]). Institute for Molecular Bioscience, 306 Carmody Rd, St Lucia QLD 4072.
    [Show full text]
  • Queensland Brain Institute 2018 Annual Report Vice-Chancellor’S Message
    Queensland Brain Institute 2018 Annual Report Vice-Chancellor’s message The Queensland Brain Institute was established in response to two of the greatest challenges in modern science: understanding brain function and the prevention and treatments of disorders of brain function. QBI’s 450-plus research staff cohort includes dynamic group leaders, postdoctoral fellows and students, all working together to tackle these challenges. Their discoveries are regularly published in top-tier scientific journals. Indeed, the 2018 Excellence in Research for Australia (ERA) results reinforce the quality of QBI research. As in all previous ERA assessments, UQ’s neuroscience was rated “well above world standard”. This is the highest possible rating and was secured largely due to Professor Peter Høj QBI researchers’ work. Vice-Chancellor and President In the past 12 months, this team of researchers has made impressive progress. To begin, QBI has done a magnificent job advancing (EAIT) had existing links with this emerging university its promising ultrasound project. Professor Jürgen in a technological boom city. Now, SUSTech and UQ Götz and his team at the Institute’s Clem Jones are close to jointly establishing a neuroengineering Centre for Ageing Dementia Research are developing laboratory and a Master in Bioengineering, to be a device that delivers ultrasound to the brain through run through EAIT. This multifaceted relationship the skull, helping drugs and other therapeutics reach between UQ and one of the world’s most rapidly their targets more effectively. This team demonstrated rising universities offers exciting, transformative for the first time in 2015 that ultrasound can have a scientific potential.
    [Show full text]
  • Download From
    bioRxiv preprint doi: https://doi.org/10.1101/860767; this version posted December 6, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Word count abstract = 105 Word count main manuscript = 4762 without Methods References = 99 Figures = 5 Tables =nil Supplements – Supplementary File includes text & figures, Supplementary Tables in Excel document, Supplementary data in link: https://www.dropbox.com/sh/rhimyqqswxnn4wk/AACErpIc2DmrwXoOl1XD- rFva?dl=0 Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Authors Joana A Revez Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0003-3204-5396 Tian Lin Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0002-5981-1911 Zhen Qiao Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0002-4401-774X Angli Xue Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0002-0285-0426 Yan Holtz Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0002-5831-5529 Zhihong Zhu Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0002-6783-3037 Jian Zeng Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia https://orcid.org/0000-0001-8801-5220 Huanwei Wang 1 bioRxiv preprint doi: https://doi.org/10.1101/860767; this version posted December 6, 2019.
    [Show full text]