Prof. Ivan Dinev, Dsc, Phd, DVM Faculty of Veterinary Medicine Trakia University Stara Zagora, Bulgaria

VETERINARY PATHOLOGY A COLOUR ATLAS

prof. Ivan Dinev, DSc, PhD, DVM Faculty of Veterinary Medicine Trakia University Stara Zagora, Bulgaria

First edition CEVA ANIMAL HEALTH BULGARIA LTD 2020 1 VETERINARY PATHOLOGY A Colour Atlas

This book is protected by the copyright law. The reproduction, imitation or distribution of the book, in whole or in part, in any format (electronic, photocopies etc.) without the prior consent, in writing, of copyright holders is strictly prohibited.

First edition, 2020 This edition is composed and published in Bulgaria Graphic design and printing: 2M PRINT LTD ISBN: 978-954-9411-41-6

2 TABLE OF CONTENTS Preface 5 Acknowledgements 6 1. Gastrointestinal tract pathology 7 1.1. Upper gastrointestinal tract pathology 8 1.2. Stomach and forestomach pathology 19 1.3. Intestinal tract pathology 30 1.4. Hepatites and hepatoses 54 1.5. Peritonites 78 2. Respiratory tract pathology 81 2.1. Upper respiratory tract pathology 82 2.2. Lower respiratory tract pathology 89 3. Pathology of cardiovascular and haematopoietic systems 112 3.1. Pericardites 113 3.2. Endocardites 119 3.3. Infarctions 125 3.4. Other cardiovascular disorders 129 3.5. Pathology of the haematopoietic system 138 3.5.1. Lymph node pathology 138 3.5.2. Spleen pathology 144 3.5.3. Bone marrow pathology 149 3.5.4. Thymus gland pathology 150 4. Pathology of nervous and endocrine systems 151 5. Pathology of musculoskeletal and integumentary systems 164 5.1. Skin lesions 165 5.2. Musculoskeletal lesions 179 5.3. Skin and musculoskeletal neoplasms 189 5.4. Deformities associated with trunk development 204 6. Urogenital system pathology 210 6.1. Urinary tract pathology 211 6.2. Genital tract pathology 236

Alphabetic index 253 3 Prologue: If there was no pathology …?

Prologue: If there was no pathology …?

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4 PREFACE In the spirit of similar previous publications of ours in the field of avian diseases, with proven practical orientation and good reception among practitioners, diagnosticians, etc., this edition is designed for use in pathomorphological diagnostics and differential diagnosis of diseases in various animal species and categories (farm animals and pets). The relatively long collection period (nearly a complete professional career) has enabled us to demonstrate characteristic lesions of diagnostic value in some common and less common diseases in these animal species. In the light of our practical experience in the diagnosis at macro- and micromorphological level, the distinctive lesions in various disease states of both infectious and non-infectious etiology, neoplasms and malformations are described. In general, they are all put in context for trainees, practitioners and pathologists and in our belief, new knowledge necessary for the interpretation of veterinary pathomorphology is generated and complemented. Of course, the dynamics of pathological processes associated to new and emerging pathogens remain a huge challenge. In support of this, the book includes demonstration of lesions characteristic of diseases from the distant past, yet still encountered nowadays; those thought to be controlled by immunoprophylaxis, etc., but still challenging, as well as emerging illnesses, unknown until recently. These circumstances necessitate maintening a high level of knowledge and experience in the field of pathoanatomical diagnostics, which is important or essential in some animal husbandry branches assisting in important medical decisions on therapy, control or eradication. The book is structured into sections based on the pathology of the individual anatomical systems of the animals. A relatively complete index is provided for easier navigation. All figures in this edition are coloured, allowing clear demonstration of the specific features of pathological manifestations. The explanatory texts to the illustrations, in addition to the description of findings, contain essential information on the etiology, pathogenesis and differentiation from similar conditions aimed at focusing the attention of specialists to a specific diagnosis. Truely convinced that what a picture/photograph shows is sometimes difficult to describe even with many words, the main approach of the book is the use of photo material. Our experience in the field of training also gives us reason to claim that this is the most comprehensible way of identifying lesions in individual nosological units. All photos in this book are original and taken during our research and diagnostic consultative work. The atlas contains a total of 702 colour illustrations, of which 596 (85%) are macroscopic and 106 (15%) are microscopic. The significant share of photographs showing macroscopic pathology in animals is intended to make the book available to a broader auditory. The relatively modest number of microscopic images is chosen with the same purpose but at the same time emphasises the diagnostic value of histological examination in some diseases. We believe that this synthesised form would be able to present a balanced overview of current issues in veterinary pathology, important for daily diagnostic practice. We hope that the publication will complement some new issues of knowledge and increase the confidence of specialists in the diagnosis of animal diseases. We look forward that our book will be well-received by among fellow veterinarians, veterinary students, livestock specialists and pet owners. This edition is also offered in an extended electronic version, which could be used for training of graduate students and young colleagues, based on extensive opportunities for discussion on the included issues.

January 2019 Prof. Ivan Dinev Stara Zagora Department of General and Clinical Pathology Faculty of Veterinary Medicine Trakia University - Stara Zagora

5 ACKNOWLEDGEMENTS

In relation to the completion of this book, I would like to, first and foremost, express my gratitude towards the company Ceva Animal Health Bulgaria Ltd. These are the people who, just a little over a decade ago, believed in my potential and accepted my proposal for the creation of such a book. I will use this opportunity to express my special gratitude and recognition towards my exceptional supporters for their trust and eagerness to publish this work. I am fully aware of the significance of this highly charitable cause and hope that this will be evident in the content and quality of this book. Another of my professional ideas was accomplished thanks to Ceva Animal Health Bulgaria Ltd. Personally, alongside my parents, my family, and my teachers, I am once more grateful to fate, which gave me the chance to bear direct responsibility with regard to healthcare in one of the sectors of industrial animal husbandry, and also the opportunity to practice in scientific research. Bring the issues of veterinary pathologyPrologue: fromIf there the wasfield no into pathology the research …? laboratory, the chance to achieve their clarification and provide feedback for the production process turned out to be the opportune moment, which made me professionally and creatively capable of completing several similar publications in this field. The combination of these activities helped me realise what one of the most needed handbooks could be to a veterinary practitioner, and eventually address this necessity. By fulfilling these duties, I bore a dual responsibility. On one hand, the responsibility for healthcare in the field, and on the other – the responsibility for the crucial moment in this process – the correct diagnosis. I would like to express my gratitude to all of my practitioner colleagues who trusted in our potential and provided us with materials for macro- and microscopic examination in a number of cases during the challenging process of diagnosing animal illnesses. My greatest satisfaction has always been to receive feedback from our practitioner colleagues on the significance of our patho-morphological diagnostics in their practice. This was an undeniably motivating factor, which engaged us into the preparation for this book’s publication. I give my thanks to the team of the histopathological examination laboratory of the Department of General and Clinical Pathology at the Faculty of Veterinary Medicine, Trakia University – Stara Zagora for their meticulously crafted materials during our diagnostic and research work in the field of veterinary pathology, with some of the microphotographs in this atlas being based on their work. Last, but not least, I would like to express my thanks for several photos from the personal archive of Associate Professor Dimitar Stoykov, PhD, which were courteously provided by his heirs, included in the atlas under the numbers 1.1-13; 1.2-20; 1.2-21; 1.3-21; 1.3-49; 1.3-56; 1.3-57; 2.1-9; 2.2- 45; 2.2-67; 3.4-10; 3.4-11; 3.1-15; 3.5.1-6; 5.1-36; 6.2-34 and 6.2-35. Thanks to all who made this book a reality!

This book has been published thanks to the kind support of Ceva Animal Health Bulgaria Ltd. January, 2019 Stara Zagora Prof. Ivan Dinev

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4 7 1.1.1.1. UPPERUPPER GASTROINTESTINAL GASTROINTESTINAL TRACT TRACT PATHOLOGY PATHOLOGY

1.1-1 Fluorosis, sheep. High dietary or drinking water fluoride concentrations are the cause of dental fluorosis 1.1-1 Fluorosis,in men and sheep. animals. High Early dietary and or moderate drinking lesionswater fluorideare manifested concentrations with appearance are the cause of brown of dental or black fluorosis spots and in mentooth and enamelanimals. erosion. Early and moderate lesions are manifested with appearance of brown or black spots and tooth enamel erosion.

1.1-2 Odontolithiasis - dental calculus, 1.1-2 dog.Odontolithiasis In dogs, dental - dental calculus calculus, (tartar) dog. is In a dogs,mixture dental of calcium calculus phosphate (tartar) and is a mixturecalcium of carbonate calcium phosphate with organic and mat- calciumter, carbonatedeposited on with the organic buccal surface mat- of ter, depositedteeth. The on conditionthe buccal issurface a prerequisite of teeth.for The gingivites condition and isperiostites. a prerequisite for gingivites and periostites.

1.1-3 Pellagra, dog. Hypovitaminosis 1.1-3 PP,Pellagra, niacin (vitamin dog. Hypovitaminosis PP) deficiency, dog. PP, niacinIn dogs, (vitamin pellagra PP) isdeficiency, manifested dog. with in- In dogs,flammation pellagra isand manifested ulcerations with of oralin- mu- flammationcosa, tongue and ulcerations gangrene of (black oral mutongue).- 8 cosa, tongue gangrene (black tongue). 8 1.2-13 Parasitic (botfly) gastritis, horse. Gastrophilus sp. larvae are parasites on equids. They migrate to the stomach where colonise the mucosa. The inflammation results in catarrhal to catarrhal haemorrhagic gastritis and appearance of crater-like necrotic ulcerations on the site of attachment of larvae.

1.2-14 Paramphistomum proventriculitis, cattle. At necropsy, young Paramphisto- mum worms are detected on the duo- denal and abomasal mucosae, and in chronic infection – adult trematodes in the rumen and reticulum. The invasion results in catarrhal to catarrhal haemorrhagic proventriculitis, diarrhoea and progressive weight loss.

1.2-15 Parasitic abomasitis (Ostertagia circumcinta), goat. Chronic inflammatory response is manifested as multiple granulomas surrounding the parasites. Granulomas attaining 5-6 mm in diam- eter and having a central groove are raised above the mucosal surface.

23 1.3-37 Porcine proliferative enteritis (Lawsonia intracellularis infection), pigs1.1. (PPE). L. intracellularis infects epithelial UPPER GASTROINTESTINAL TRACTcells andPATHOLOGY lives intracellularly. Clinically, PPE is manifested with intermittent diarrhoea. Retarded growth (ununifor- mity) in a group of fattening pigs.

1.3-38 Proliferative haemorrhagic enteropathy is one of pathological manifestations of disease. It is characterised with bloody content and fresh blood clots in the ileal and caecal lumen.

1.1-2 Odontolithiasis - dental calculus, dog. In dogs, dental calculus (tartar) is a mixture of calcium phosphate and calcium carbonate with organic matter, deposited on the buccal surface of teeth. The condition is a prerequisite for gingivites and periostites.

1.3-39 In other cases, PPE appears as necrotic enteritis with alterations affecting the ileal and ileocaecal valve mucosa.

1.1-3 Pellagra, dog. Hypovitaminosis PP, niacin (vitamin PP) deficiency, dog. In dogs, pellagra is manifested with inflammation and ulcerations of oral mucosa, tongue gangrene (black tongue). 8 42 1.4-19 Chronic parasitic hepa- 1.1. titis. Organisa- tion UPPER via sub- GASTROINTESTINAL TRACT PATHOLOGY stitution of necrotic liver tissue by connective tissue in parasitic tracks. Dicrocoeliasis (Dicrocoelium dendriticum – lancet liver fluke), sheep.

1.1-1 Fluorosis, sheep. High dietary or drinking water fluoride concentrations are the cause of dental fluorosis in men and animals. Early and moderate lesions are manifested with appearance of brown or black spots and tooth enamel erosion. 1.4-20 Pericanalicular interstitial hepatitis, dicrocoeliasis, sheep. Parasites (f) are found in bile canaliculi, and the pericanalicular connective tissue has ingrown as a result of intensive inflammatory proliferations (H), leading to atrophy of the parenchyma.

1.4-21 Parasitic hepatitis, hepatic coccidiosis, rabbit. The causative agent of hepatic coccidiosisis in rabbits is E. stidae. The liver is enlarged at various extents, and its surface, including the cross surface, are spattered with multiple nodular structures of a size varying from several millimeters to 1 cm.

2.1-1 Rhinorrhagia – bleeding from the nose, rabbit, haemorrhagic septicaemia. The disease course is hyperacute and usually asymptomatic, with only nosebleeds as occasional findings.

2.1-2 Mucopurulent rhinitis and conjunctivitis, cat, infectious rhinotracheitis. The lesions affect the eyes and airways. The causative agent is a ubiquitously spread feline herpes- virus, serotype 1.

2.1. UPPER RESPIRATORY TRACT PATHOLOGY

2.1-3 Catarrhal purulent rhinitis and conjunctivitis, myxomatosis, rabbit. Myxomatosis is a highly lethal disease for European rabbit (Oryctolagus cu- niculi). It is characterised with subcutaneous oedemas, releasing a mucoid secretion after incision. The lesions are encountered around body orifices, mostly on the face, especially the eye- lids. 2.1-1 Rhinorrhagia – bleeding from the nose, rabbit, haemorrhagic septicaemia. The disease course is hyperacute and usually asymptomatic, with only nosebleeds as occasional findings.

2.1-2 Mucopurulent rhinitis and conjunctivitis, cat, infectious rhinotracheitis. The lesions affect the eyes and airways. The causative 82 agent is a ubiquitously spread feline herpes- virus, serotype 1.

82 2.2-19 A specific clinical manifestation of contagious pleuropneumonia in cattle are the mucoid purulent nasal discharges and severe body emaciation (ca- chexia). Progressive pneumonia is characterised with intermittent fever, loss of appetite, painful breath- ing with the neck and head stretched forward. The ribs are clearly outlined on the thoracic wall.

2.2-20 Actinobacillus pleuropneumonia (APP), pig. Lower parts of all pulmonary lobes (anterior, cardiac, middle and anterior diaphragmatic) are affected causing fibrosis of tissue. Lesions are rose to gray-coloured dense areas and resemble lung with atelectasis.

2.2-21 APP, pig. Cross section of affected areas shows a meat-like consis- tency, but it is not as firm. In the early and intermediate stages of the disease, catarrhal exudate is present in the airways.

95 112 3.2-13 Verrucous endocarditis, pig, ery- sipelas (Erysipelothrix rhusiopathiae infection). Loose thrombotic masses with valvular and adjacently, parietal locali- sation in the left half of the heart.

3.2-14 Parasitic endocarditis, dirofilariosis, dog. The parasites are located in the right ventricle of the heart, di- rected to and entering the pulmonary artery. The mechanical irritation of parasites and their metabolic products are the cause of parietal endocarditis.

3.2-15 Parasitic endocarditis, echinococ- cosis, sow. A large echinococcal cyst (Echinococcus unilocularis), 6-7 cm in di- ameter, associated to the left ventricu- lar endocardium.

123 3.5. PATHOLOGY OF THE HAEMATOPOIETIC SYSTEM The haematopoietic system includes organs and tissues as bone marrow, lymph nodes, spleen and thymus, involved in the production of blood cells.

3.5.1. LYMPH NODE PATHOLOGY

3.5.1-1 Tuberculous lymphadenitis, cattle. Tubercle in a mediastinal lymph node with caseous necrosis, cut surface (symmetrical halves). In general, lesions in bovine tuberculosis are predominantly detected only in regional lymph nodes, without alterations in the respective organ (incomplete primary complex).

3.5.1-2 Tuberculous lymphadenitis, cattle, mediastinal lymph nodes. Mac- roscopically visible caseous necrosis alterations (arrows). The appearance of caseous necrosis (secondary caseosation) is specific for late stages of development of tuberculomas in bovine tuberculosis.

3.5.1-3 Tuberculous lymphadenitis, cattle, bronchial 3.5. lymph nodes. Caseous necrotic lesions, well outlined on thePATHOLOGY cut surface. The areas that OF have undergoneTHE HAEMATOPOIETICcaseous SYSTEM necrosis are transformed into a homogenous granular mass, distinguishedThe haematopoietic from the surrounding system tissue includes by its organs and tissues as bone marrow, lymph palernodes, colour. spleen and thymus, involved in the production of blood cells.

3.5.1. LYMPH NODE PATHOLOGY

3.5.1-1 Tuberculous lymphadenitis, cattle. Tubercle in a mediastinal lymph node with caseous necrosis, cut surface (symmetrical halves). In general, lesions in bovine tuberculosis are predominantly detected only in regional 138 lymph nodes, without alterations in the respective organ (incomplete primary complex).

3.5.1-3 Tuberculous lymphadenitis, cattle, bronchial lymph nodes. Caseous necrotic lesions, well outlined on the cut surface. The areas that have undergone caseous necrosis are transformed into a homogenous granular mass, distinguished from the surrounding tissue by its paler colour.

138 151 4. PATHOLOGY OF NERVOUS AND ENDOCRINE SYSTEMS

4. PATHOLOGY OF NERVOUS AND ENDOCRINE SYSTEMS

4 -1 Massive congestion and colliquative necrosis, brain, calf, hypovitaminosis В1. The condition is also known as cerebrocortical necrosis or polioencephalomalacia. Me- ninges are severely oedematous, hyperaemic and with haemorrhages. 4-2 Cerebrocortical colliquative necroses, brain, hypovitaminosis В1, calf. Col- liquative and haemorrhagic foci only in the gray matter of brain hemispheres’ cortex. In a slow course or in subjects that remitted from disease, cyst-like caverns may form as a result of necrotic lytic processes.

4-2 Cerebrocortical colliquative necroses, brain, hypovitaminosis В1, calf. Col- liquative and haemorrhagic foci only in 4-3 Listeriosis,the gray matter sheep, of meningoence brain hemispheres’- phaliccortex. form, clinicalIn a slow signs course of depression. or in subjects Listeriosisthat is remitted an enzootic from infectious disease, dis cyst-like- ease cavernscaused bymay L. formmonocytogenes. as a result of necrotic lytic processes.

152

4-3 Listeriosis, sheep, meningoence- phalic form, clinical signs of depression. Listeriosis is an enzootic infectious disease caused by L. monocytogenes.

152 164 5.1-31 Psoroptic mange, sheep. The commonest, severe form of mange in sheep. It is caused by the mite Psoroptes ovis, that parasitises on skin surface and feed on blood and lymph. One of the first signs is pruritus, and animals are continuously scratching in surrounding objects. The wool begins to fall down to reveal denuded skin areas, most frequently on the back and the neck.

5.1-32 Psoroptic mange, sheep. The skin of denuded areas is rough and thicker due to bulky crusts’ cover. In gener- alised process, the wool falls down all over the body except for some small areas on the abdomen and legs. The disease has a marked autumn-winter and spring seasonal pattern. Predispos- ing factors are high humidity and high population density in animal premises.

5.1-33 Demodectic mange, dog. It is caused by Demodex canis. Clinically, it is characterised with hair loss usually beginning from the head and gradually affecting the entire body. The pruritus is mild or could be absent. In secondary contamination, most commonly with Staph. аureus, multiple pustules appear on the skin.

175 5.2-13 Rachitic rosary, pig. When the rib ends at costochondral junctions with the sternum are affected, knobs of non-mineralised cartilaginous matrix are formed, known as rachitic rosary.

5.2-14 Rickets, pig. The manifestations of rickets in animals result in delayed growth of long bones and specific thick- ening of metaphyses. Rickets lesions are detected in the growth plate areas, located in metaphyses.

5.2-15 Rickets, dog, deformity of legs. The growth plate is the site where the bone elon- gation takes place, and is characterised by active growth of chondrocytes. Generally, etiological factors are dietary deficiency in calcium (Ca), phosphorus (P) and vitamin D3; impaired Ca/P ratio or impaired utilisation of one of these elements.

183 5.2-25 Marked icteric tint of conjunctivae, eye sclera (left) and vaginal mucosa (right) in a case of anaplasmosis, cattle. Anaplasmosis is a transmissive disease affecting mainly cattle and less frequently, small ruminants.

5.2-26 Icteric tint of urinary bladder mucosa in a case of bovine anaplasmosis. Anaplasmosis is accompanied with signs of fever, severe anaemia and icterus, with anaemic being the primary sign from the compound symptom complex.

5.2-27 Anaplasmosis, cattle. Intensive icterus reflected by subcutaneous and omental fat, due to extravascular haemolysis (lysis of erythrocytes, mainly in the spleen and the liver).

187 5.3-4 Fibropapilloma, calf. Rough, cauliflower-like appearance of the tumour with keratinised surface. Tumour growths are multiple and could be gen- eralised5.3-4 overFibropapilloma, the almost entire calf. body,Rough, presentingcauliflower-like a typical appearance papillomatous of the ap tu- - pearancemour with and keratinised size varying surface. from 0.5Tumour cm togrowths large confluating are multiple thick, and rough,could becauli gen- - flower-likeeralised overstructures. the almost entire body, presenting a typical papillomatous appearance and size varying from 0.5 cm to large confluating thick, rough, cauliflower-like structures.

5.3-5 Fibropapilloma, cut surface. Bo- vine fibropapillomas are usually located in the region of the head, neck, back, legs and udder. The tumours are exo- phytic,5.3-5 sometimesFibropapilloma, on a cut wide surface. base or Bo - pendulating.vine fibropapillomas are usually located in the region of the head, neck, back, legs and udder. The tumours are exo- phytic, sometimes on a wide base or pendulating.

5.3-6 Early stage of formation of a squamous cell carcinoma with formation of a papilloma in the periocular skin (arrows) in a Monbéliarde cow. Oc- ular5.3-6 squamous Early stage cell carcinoma of formation in cattle of a is squamousassociated cellwith carcinoma several risk with factors forma as - genetiction of predisposition, a papilloma innon-pigmented the periocular skinskin in (arrows) the orbital in a Monb area, é UVliarde radiation, cow. Oc - injuryular fromsquamous insects cell etc. carcinoma in cattle is associated with several risk factors as genetic predisposition, non-pigmented skin in the orbital area, UV radiation, injury from insects etc.

190

190 210 6.1-7 Numerous petechiae and major hemorrhages at the background of hyperemic kidney, african swine fever, wild boar (above). Numerous petechiae at the background of a pale anaemic kidney, acute form of classical swine fever, the so-called „turkey egg kidney“ (bottom). The direct impact of the virus on blood vessels results in damaged vascular endothelium, hyalinization of capillary walls and perivascular inflammatory cell proliferation, with resulting vasoconstriction and occlusion.

6.1-8 Haemorrhagic nephritis, circovirus infection, porcine dermatitis and ne- phropathy syndrome (PDNS). Numer- ous petechiae and larger haemorrhages on the surface. Enlarged size, preserved normal colour of the kidney – it is not anaemic as in classical swine fever.

6.1-9 Variants of macromorphological expression of haemorrhagic nephritis, circovirus infection, PDNS. The conditions is also characterised with proliferative necrotising glomerulonephritis. PDNS lesions are associated with immune complex-mediated damage. The in situ formed and deposited immune complexes in the walls of glomerular capillaries initiate inflammation. 213 6.1-67 Haemorrhagic cystitis (left) and urolithiasis (right), FLUTD, tomcat. The predisposition of male cats to FUS is due to anatomical features of urethra, which is longer and narrower. Long intervals between micturitions, reduced locomotor activity and diet composition contribute to formation of microcrystals and uroliths.

6.1-68 Urolithiasis, calculi, urinary bladder, tomcat. When calculi are located within the urinary bladder, the condition is also termed cystolithiasis. Cal- culi in urinary tract, ureters and urethra could lead to complete obstruction. The chemical composition of uroliths is the same as that of renal calculi.

6.1-69 Uroliths varying from sediment to shaped calculi, urinary bladder, dog. Visible uroliths with a size of several millimeters are termed “sand” or “sem- olina”. Larger firm and solid sediment structures are called stones (calculi). In some cases, they could attain several kilograms.

233 6.2-13 Bilateral, ovarian inclusion cysts (C), ovaries, mare. Right – cut surface. They are also termed ovulation fossa inclusion cysts or germinative inclusion cysts. These are epithelium-lined structures formed in response to trauma or wounds. The development of ovarian inclusion cysts is associated with repeated ovulation cycles. They are usually multiple, persist over a long period of time and slowly increase their size. Their enlargement leads to compression atrophy of ovarian tissue and function loss.

6.2-14 Cystic formations, ovaries (C), bitch. Follicular cyst is a cyst resembling the Graafian follicle and is larger than the normal follicle. The size of the lat- ter should be considered for diagnostic purposes. The presence of follicular cyst could be also assumed if it appears rather larger than surrounding follicles.

6.2-15 Neoplastic formations (leiomyoma) affecting the ovary (o) and the uterine wall (u). Leiomyoma is a be- nign mesenchymal tumour that is commonly seen in the uterus, but rarely in ovaries. Primary ovarian leiomyoma is a rare6.2-13 neoplasm. Bilateral, In ovarian most cases,inclusion ovarian cysts (C), ovaries, mare. Right – cut surface. They are also termed ovulation leiomyomasfossa inclusion are cystsencountered or germinative together inclusion cysts. These are epithelium-lined structures formed in response to withtrauma uterine or wounds.leiomyomas. The development of ovarian inclusion cysts is associated with repeated ovulation cycles. They are usually multiple, persist over a long period of time and slowly increase their size. Their enlargement leads to compression atrophy of ovarian tissue and function loss.

6.2-14 Cystic formations, ovaries (C), bitch. Follicular cyst is a cyst resembling the Graafian follicle and is larger than the normal follicle. The size of the lat- ter should be considered for diagnos- 240 tic purposes. The presence of follicular cyst could be also assumed if it appears rather larger than surrounding follicles.

240 ALPHABETIC INDEX А caseosation, 63 catarrhal mastitis, 242 abomasitis, 19, 21, 23 cerebrocortical colliquative necroses, 152 abrachia, 207 cheiloschisis, 17 abscess, 62, 63, 93, 94, 146, 154, 172, 179, 248 cholecystitis, 65, 71 acardius amorphus, 205 chondrosarcoma, 198 acid haematin, 21, 22 cicatrix, 25, 36, 73, 127, 212, 217, 228 acidosis, 25 circovirus infection, 165, 213, 214 actinobacillary pleuropneumonia, 91, 95 cirrhosis, 72, 73, 74 Actinobacillus pleuropneumoniae, 96, 114 Cl. рerfringens, 32, 33, 37, 39, 57, 80, 145, 225 Actinomyces israelii, 179 classical swine fever, 36, 141, 213, 232 actinomycoma, 140 coagulative necrosis, 58, 63, 173 actinomycosis, 178 coagulum, 20, 22, 133 adactilia, 207 coccidiosis, 40, 60, 61 adenocarcinoma, 108, 160, 193, 194, 235, 246, 251 Coenurus cerebralis, 156 adenoma, 51, 76, 193, 245 congestion, 54, 105, 145, 152 agnathia superior, 206 conglobates, 29 alopecia, 178 contagious ecthyma, 169 amyloidosis, 66 croupous pleuropneumonia, 97 anaemic infarction, 127, 147, 226, 227 cruor sanguinis, 133 anaplasmosis, 145, 146, 187, 238 crusta lardacea, 133 anemia, 20, 57, 80, 88, 187 crusts, 167, 169, 173, 175, 176 aneurisma, 127, 132 cryptorchism, 250 aniridia congenita, 255 cuprotoxicosis, 56, 225 anthracosis, 106 cyanosis, 54, 165 aplasia, 162 cystadenoma, 76, 245 apodia, 207 Cysticercus ovis, 180 apostematous pneumonia, 94 сoenurosis, 156, 157 Ascaris suis, 48, 61 Сysticercus tenuicollis, 59 ascites, 80 Asperigillus pneumonia, 101 D atelectasis, 106 atherosclerosis, 131, 132 decubitus, 176 atrophia cyanotica hepatis, 54 degeneration, 39, 55, 58, 68, 70, 148, 181, 182, 189, atrophic cirrhosis, 73 201, 219, 223 atrophy, 54, 55, 60, 61, 73, 74, 77, 102, 106, 157, 191, Delafondia vulgaris, 124, 132 219, 220, 222, 223, 224, 242 demodectic mange, 175 dermatitis, 165, 170, 247 B dermatophytosis, 173, 174 diathesis urica, 71 basal cell carcinoma, 192 diathesis visceralis, 71 bezoir, 29, 49, 50 dicrocoeliasis, 60 biliary cirrhosis, 73 Dicrocoelium dendriticum, 60 bovine malignant catarrhal fever, 13, 84, 85, 86, 158 dilatatio cordis, 129, 130 bovine viral diarrhoea/mucosal disease, 9, 10, 11, 21, dilation, 17 31, 118, 124 diphtheroid colitis, 35 brachignathia, 207 diphtheroid typhlitis, 36 bronchopneumonia, 89, 92, 93, 99 diprosopus, 206 dirofilariosis, 123 C dislocation, 27, 47, 50 duplicatus incompletа posterior, 204, 205 calcificatio asteroidеs, 134 dysentery, 37, 38 calcinosis, 128 calculi biliares, 71 E calculi salivares, 16 calicivirus, 24, 87, 98, 212 ecchymoses, 19 cancroid, 192 Echinococcus granulosus, 61, 101 carcinoma, 15 Echinococcus unilocularis, 61, 65, 101, 123, 222 cardiac cirrhosis, 73 Eimeria species, 30, 40, 61 cardiac tamponade, 118, 127 embolism, 108, 125 253 empyema, 89 hydrocephalus, 162, 206 encephalitis, 184 hydronephrosis, 223 endocarditis, 119, 120, 122, 123, 132, 214 Hydropericardium, 113 endometritis, 236, 237, hyperaemia, 54, 55, 70, 73, 84, 119, 144, 165, 167, 211, enteritis, 30, 31, 32, 33, 37, 40, 41, 42, 43, 44, 80 212 enterocolitis, 33, 165 hyperkeratinisation, 25, 27, 176, 177, 178 enteropathy, 39, 40, 42 hyperplastic enteritis, 44 enterotoxaemia, 32, 33 hyperthyroidism, 160, 161 epidermitis serosa, 166 hypertrophy, 74, 129, 224, 251 epidermoid cyst, 209 hypoplasia, 161, 162, 231, 250 epulis, 14 hypovitaminosis E, 180, 181 Erysipelothrix rhusiopathiae, 19, 122, 123 exudative epidermitis, 166 I F ichthyosis congenita, 176, 177 icterus, 56, 57, 71, 80, 108, 187, 188 fatty infiltration, 67, 224 ileus, 45, 46, 48, 49 fibroadenoma, 245 infectious epididymitis, 247 fibroma, 195, 196 infectious rhinotracheitis, 82, 84, 86, 89 fibromyxosarcoma, 110, 199, 231 interstitial pneumonia, 102 fibropapilloma, 189, 190, 252 intestinal emphysema, 45 fibrosarcoma, 148, 196, 199 invagination, 47, 48 fibrosation, 114, 131, 139, 140, 186, 219, 220, 222, 247 ischaemia, 131, 176, 227 fluorosis, 8 follicular cyst, 240 J fowlpox (diphtheritic form), 9 fungi imperfecti, 173 Johne’s disease, 44 G K

gallstones, 71 keloid, 185 ketosis, 68 gangrenous mastitis, 243 gangrenous pneumohia, 99, 100 L gastritis, 19, 20, 23 gastroenteritis, 32 laryngitis, 85, 86 gingivitis, 8, 9, 10, 12, 14 laryngotracheitis, 86, 87 glioma, 159 Lawsonia intracellularis, 42 glomerulonephritis, 211, 212, 219 leiomyoma, 51, 240, 241 granulomatous inflammation, 44, 146 leiomyosarcoma, 202 leptospirosis, 56, 57, 58, 120, 144, 217, 218, 219, 232 H leukoplakia, 11 leukosis enzootica bovum, 74 haemangioma, 230 leukosis, 26, 52, 74, 75, 135, 141, 142, 143, 147, 230 haemangioma, 76, 134 lien lobatus, 149 haemangiopericytoma, 134 Linguatula serata, 83 haemangiosarcoma, 88, 110, 148 linguatulosis, 83 haematomas, 119, 251 lipidosis, 69 haemoglobinuria, 57, 80, 232 lipoma, 198 haemolysis, 56, 187, 225, 232 liposarcoma, 197 haemopericardium, 118 liquefactive necrosis, 63, 152 haemorrhagic cystitis, 232, 233 listeriosis, 152, 153, 154 haemorrhagic disease, 24, 161, 211, 212 lithotherion, 239 haemorrhagic infarction, 47, 72, 109, 126 lymphadenitis, 33, 138, 139, 141 haemorrhagic nephritis, 213 lymphangiosarcoma, 53 haemorrhagic pneumonia, 98, 99 lymphoid leukosis, 26, 52, 74, 75, 141, 142, 143, 147, 230 haemorrhagic septicaemia, 82 lymphoma, 135, 143 hepar moschatum, 55 hepatitis apostematosa, 62 M hepatitis, 56, 57, 58, 60, 61, 62, 63, 64, 65 Hermaphroditism, 241, 250, 252 mastocytoma, 149, 200 hexamitiasis, 30 melanoma, 76, 111, 195 254 hyalinisation, 180, 181, 213, 220, 222 melanosis maculosa, 70, 107, 143, 238 melanosis, 70 pleuritis, 78, 88, 89, 90, 91 meningoencephalitis,153, 154, 155, 156 pneumonia crouposa, 91, 96, 97, 98 metaplasia, 130, 148, 170, 178, 244 pneumonosclerosis, 107 meteorism, 50 pododermatitis, 185 mucoid degeneration, 223 polipodia, 207 Multiceps multiceps, 156 polycystic kidney, 224 muscular degeneration, 181, 182 polydactilia, 208 mutilatio, 173 polyserositis, 29 Mycobacterium avium, 64, 104 porcine proliferative enteritis, 42, 43 Mycobacterium bovis, 103, 138, 139, 140, 146 pox, 105, 168 Mycobacterium paratuberculosum, 44 prognathia, 207 Mycoplasma mycoides, 91, 94 prosoplasia, 12, 148 mycotic pneumonia, 104 proventriculitis, 23 myxofibroma, 196 Psoroptes ovis, 175 myxomatosis, 200, 201 psoroptic mange, 175 pulmonary hypertension, 129, 130 N pyelonephritis, 216 pyometra, 236 necrotic enteritis, 32, 37, 42 necrotic hepatitis, 63 R nephritis, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 237 rachitic rosary, 183 nephrolithiasis, 229, 230 rectal prolapse, 50 nephrosclerosis, 222 rhinorrhagia, 82 nephrosonephritis, 217, 219, 224 rhusiopathia suum, 19, 121, 122, 123, 165, 212, 226 neurinoma, 159 rickets, 182, 183 roseola, 167 O S obstruction, 18, 233, 234 odontolithiasis, 8 sarcoma, 14, 15, 75, 77, 88, 134, 136, 159, 202, 239 oedema disease, 34, 156 schistosoma reflexum, 205 oestrosis, 83 scirrhous carcinoma, 194 Oestrus ovis, 83 seminoma, 249 oral papillomatosis, 16 sequester, 251 orchitis, 247, 248 shwannoma, 159 osteoarthritis, 184 splenitis tuberculosa, 146 osteomyelitis, 149, 179 splenomegaly, 144, 145 osteosarcoma, 203 squamous cell carcinoma, 190, 191, 192, 235 Ostertagia circumcinta, 23 Staphylococcus hyicus, 166 steatosis, 67, 68, 69 P stenosis, 129, 131 stomatitis, 9, 13, 85, 169 palatoschisis, 17 Streptococcus suis type 2, 120 pancreatitis, 77 suppurative pneumonia, 93, 94 papilloma, 189, 190, 244 syndactilia, 209 papula,168 synechia, 65, 91 parakeratosis, 176 paratuberculosis, 44 T paratyphoid, 35 pasteurellosis, 87, 89, 90, 97, 98, 113, 172 Taenia hydatigena, 59 pellagra, 8 Taenia ovis, 180 pericarditis serosa, 113 tetanospasmin, 154 perihepatitis, 65 tetanus, 154, 155 peritonitis purulenta, 79 thoracopagus, 204 peritonitis, 78 thromboembolism, 72, 109, 132, 212, 214, 226, 228 perodactilia, 207 thrombotic endocarditis, 120, 121, 226, 228 perodermia, 178 thrombus, 56, 72, 97, 120, 121, 122, 123, 124, 132, 133, 214 peromelia, 207 toxic liver dystrophy, 69, 70 persistent right aortic arch, 136 transmissible veneral tumour, 239 petechiae, 19 Trichinella spiralis, 186 pharyngitis, 10 trichobezoirs, 49 255 Trichuris suis, 40 tridermomas, 203 trismus, 154 tuberculous granulomas, 64, 91, 103, 117 tuberculous pneumonia, 103, 104 typhlitis, 34, 36, 38 U

ulcerations, 21, 167 urate diathesis, 71 urate infarctions, 228 uricosis, 71 urolithiasis, 233 urticaria, 170 V

verminous pneumonia, 101 vesicula, 12, 167, 169 volvulus, 46, 47 Z

Zenker’s necrosis, 180, 181, 182

empyema, 89 hydrocephalus, 162, 206 encephalitis, 184 hydronephrosis, 223 endocarditis, 119, 120, 122, 123, 132, 214 Hydropericardium, 113 endometritis, 236, 237, hyperaemia, 54, 55, 70, 73, 84, 119, 144, 165, 167, 211, enteritis, 30, 31, 32, 33, 37, 40, 41, 42, 43, 44, 80 212 enterocolitis, 33, 165 hyperkeratinisation, 25, 27, 176, 177, 178 enteropathy, 39, 40, 42 hyperplastic enteritis, 44 enterotoxaemia, 32, 33 hyperthyroidism, 160, 161 epidermitis serosa, 166 hypertrophy, 74, 129, 224, 251 epidermoid cyst, 209 hypoplasia, 161, 162, 231, 250 epulis, 14 hypovitaminosis E, 180, 181 Erysipelothrix rhusiopathiae, 19, 122, 123 exudative epidermitis, 166 I F ichthyosis congenita, 176, 177 icterus, 56, 57, 71, 80, 108, 187, 188 fatty infiltration, 67, 224 ileus, 45, 46, 48, 49 fibroadenoma, 245 infectious epididymitis, 247 fibroma, 195, 196 infectious rhinotracheitis, 82, 84, 86, 89 interstitial pneumonia, 102 256 fibromyxosarcoma, 110, 199, 231 fibropapilloma, 189, 190, 252 intestinal emphysema, 45 fibrosarcoma, 148, 196, 199 invagination, 47, 48 fibrosation, 114, 131, 139, 140, 186, 219, 220, 222, 247 ischaemia, 131, 176, 227 fluorosis, 8 follicular cyst, 240 J fowlpox (diphtheritic form), 9 fungi imperfecti, 173 Johne’s disease, 44 G K

ТРУДОВ СТАЖ Д-р Динев имаWORK близо 30 EXPERIENCE годишен трудов стаж, включващ дейности на практикуващ ветеринарен лекар, преподавател във Ветеринар- номедицински факултет,Dr. Dinev Стара has Загора, served диагностик as a иvet, консултант. lecturer, Автор diagnostician е на повече от 100and научни consultant труда, значима in the част field от които of poultry в областта pathology for near 30 years. He на патологията,is author диагностиката of more и диференциалнатаthan 100 scientific диагностика pieces на болести of work, по птиците. a significant Участвал е с научниpart of доклади which в надare 40in национални the fields и of pathology, diagnostics and международни конгреси, конференции и симпозиуми. Като самостоятелен автор и в съавторство участва в написване и издаване на учебник, ръководстваdifferential за студенти и diagnosticsмонографии. of poultry pathology. Predominantly as a sole or lead author, he has published in journals such as Avian pathology, Avian diseases, World’s Poultry Science Journal, British Poultry Science, The Veterinary Record, Research in Veterinary ОБРАЗОВАНИЕ И ОБУЧЕНИЕ 1982Science, – 1987 AppliedМагистър Microbiology ветеринарен and лекар Biotechnology,, Висш институт по зоотехникаThe Journal и ветеринарна of Poultry медицина, Science, Стара Journal Загора of Applied Animal Research, The Journal of Applied2000 ОНС Poultry „Доктор“ Research, , Тракийскиetc университет,. He has participatedСтара Загора with official reports in more than 50 national and international congresses, Защитена дисертация: „Клиникоморфологични проучвания на ензоотична миелоцитоматоза при кокошки но- conferences and symposia. As an сачки, independent асоциирана с други author неоплазии“ and co-author he has participated in the writing and publishing of textbook, student’s 2013 tutorial НС „Доктор manuals на науките“ and , monographs. Тракийски университет, Стара Загора Защитена дисертация: „Патология на скелетномускулната система в бройлерното птицепроизводство (клини- коморфологични проучвания при проблемни състояния)” НАУЧНОПРЕПОДАВАТЕЛСКИ EDUCATIONAL СТАЖ RECORD: 2014 – сега 1982 професор – 1987, Тракийски университет,MSc, Trakia Стара Загора University, Stara Zagora, Bulgaria 2003 – 2014 доцент, Тракийски университет, Стара Загора 1989 – 20031997 асистент – 2000, Висш институт PhD,по зоотехника Trakia иUniversity, ветеринарна медицинаStara Zagora, Стара Загора Bulgaria Thesis Title: Clinical-morphological investigations on enzootic myelocytomatosis in АДМИНИСТРАТИВНИ ПОЗИЦИИ 2012layer – 2016 hens, заместник associated декан with по учебно-методична other neoplasms дейност , Ветеринарномедицински факултет, Тракийски университет, 2013Стара Загора DSc, Trakia University, Stara Zagora, Bulgaria

ЗАДГРАНИЧНИ СПЕЦИАЛИЗАЦИИ И ОБМЯНА НА ОПИТThesis Title: Pathology of the musculoskeletal system in broiler chickens (Clinical and morphological 1999 Ecole Nationale studies Veterinaire in problematic d’Alfort, France conditions) 2000 Poultry Department, National Vet. Center, Deventer, the Netherlands 2003 Auburn University, Alabama, USA (under the Alltech’s aegis) 2016PROFESSIONAL Faculty of Science, University TEACHING of Johannesburg, EXPERIENCE: South Africa 20162014 Department – Present of Animal Health Professor, at the Mafikeng Trakia Campus University, of the North-West Stara University, Zagora, South Bulgaria Africa ОБРАЗОВАТЕЛНИ 2003 И –НАУЧНИ 2014 ЛЕКЦИИ НА РАЗЛИЧНИAssociate ФОРУМИ, professor, ОРГАНИЗИРАНИ Trakia University, У НАС И В ЧУЖБИНА Stara Zagora, Bulgaria • Презентации 1989 за ветеринарни – 2003 лекари в семинари,Assistant организирани professor, от Trakiaфирми вносители University, на лекарства, Stara Zagora, ваксини иBulgaria хранителни добавки за животни. • Извеждане на лекционни курсове по „Обща патология“ (хорариум 60 часа) и „Болести по птиците“ (хорариум 45 часа) във факулте- та по ветеринарна PROFESSIONAL медицина при университета NON „Св. - КлиментTEACHING Охридски“, EXPERIENCE гр. Битоля, Р. Македония за академичните 2012/2013 и 2013/2014 и 2015/2016 г. 2012 – Present Associate editor of the Editorial board of Trakia Journal of Sciences СПИСЪК НА ПО-ВАЖНИТЕ НАУЧНИ ПУБЛИКАЦИИ ПРЕЗ ПОСЛЕДНИТЕ ГОДИНИ 1. Dinev, I., S. Denev, 2008. Hyperandrogenism in broiler chickens and commercial layers, Veterinary Record, 162, 23-24 (IF 1.240, 2008) 2. Dinev, I., ADMINISTRATIVE2008. Clinical and morphological POSITIONS studies on spontaneous rupture of the gastrocnemius tendon in broiler breeders, British Poultry Science, vol 49, №1,2012 7-11 (IF – 1.134, 2016 2008 ) vice dean of education to the Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria

ABROAD SHORT–TIME SPECIALISATIONS 1999 Ecole Nationale Veterinaire d’Alfort, France 2000 Poultry Department, National Vet. Center, Deventer, the Netherlands 2003 Auburn University, Alabama, USA (under the Alltech’s aegis) 2016 Faculty of Science, University of Johannesburg, South Africa 2016 Department of Animal Health at the Mafikeng Campus of the North-West University, South Africa

COMMAND OF LANGUAGES: - Working knowledge of English and Russian - Fluent in: Bulgarian 257 6. Dinev, I. & Y. Gardin, 2011. Enzootic outbreak and spontaneous regression of dermal squamous cell carcinoma in commercial layer hens. Abstract book, XVII World Veterinary Poultry Congress, Cancum, Mexico, 14-18 August, 2011, p.175 7. Dinev, I. Leg weakness pathology in broiler chickens, 2012. 15th Biennial Congress of the International Society for Animal Clinical Pathology & 14th Conference of the European Society of Veterinary Clinical Pathology, Ljubljana, Slovenia, from July, 3rd - 7th 2012, Proceedings, p.179 8. Dinev, I. 2013. Pathomorphological investigations on the incidence of axial skeleton pathology associated with posterior paralysis in commercial broiler chickens, 2013. Abstract book, XVIIIth World Veterinary Poultry Congress, Nantes, France, 19-23 August, 2013, p.523 9. Dinev I. & S. Denev, 2013. Clinical and morphological studies on spontaneous cases of Pseudomonas aeruginosa infections in chickens. Abstract book, XVIIIth World Veterinary Poultry Congress, Nantes, France, 19-23 August, 2013, p.320

ДРУГИ АВТОРСКИ ИЗДАНИЯ OTHER AUTHORIAL WORKS 1. Динев, И., 2014. Обща ветеринарна патология, учебник за сту- денти, първо1. Dinev, издание, I., изд.2014 „Дъга+“,. General Ст. Загора, Veterinary ISBN: 978-954-9387-84-1 Pathology,2. student’sДинев, И.textbook,,2017. Обща first ветеринарнаedition, ISBN: патология,978- Второ изд., 954-9387-84-1,”Дъга+” ООД, Стара(in bulgarian Загора,) ISBN: 978-619-7251-08-1 Важен2. Dinev, момент I., при 2017 създаване. General на книгата Veterinary беше не само отразяване Pathology, student’s textbook, second edition, ISBN: 978- на материята „Обща ветеринарна патология“ от гледна точка на нейния 619-7251-08-1, (in bulgarian) http://uni-sz.bg/truni6/ wp-content/uploads/vmf/file/OVP%20second%20образователен характер за студенти по ветеринарна медицина, а и ed%20present.pdfпредставянето и откъм страната на възможностите на нейната диагно- стична стойност във ветеринарномедицинската лабораторна и клинична практика.The Отделните idea behind тематични the creation единици of this представяха book was възможности за 6. Dinev, I. & Y. Gardin, 2011. Enzootic outbreak and spontaneousnotзапознаване regression only to reflect of с основниdermal on the squamous макро- subject и микроскопскиcellof Generalcarcinoma Veterinary лезии in commercial при дегенеративни, layer hens. Abstract book, XVII World Veterinary Poultry Congress, Cancum, Mexico, 14-18Pathologyнекробиотични, August, in 2011, terms възпалителни,p.175 of its educational регенеративноприспособителни, character for цир- 7. Dinev, I. Leg weakness pathology in broiler chickens, 2012. 15thveterinary Biennialкулаторни, Congress students, имунологични of thebut International also и неопластичниto present Society and forизменения, Animalfurther Clinical водещи Pathology до съот &- 14th Conference of the European Society of Veterinary Clinical Pathology, Ljubljana,theветните possibilities Slovenia,отклонения of from its в July,здравнияdiagnostic 3rd - 7 thстатус value2012, на Proceedings,in организма. veterinary p.179 Това обезпечаваше laboratory and clinical practice. The individual thematic units give an opportunity to get acquainted with the basic macro- изграждане 8. Dinev, на I. основни 2013. Pathomorphological знания и приложението investigations им при on изучаване the incidence на специфичните of axial skeleton болестни pathology единици associated в специалната with posterior патологична paralysis in commercial анатомия. Заand онагледяване microscopic на lesions макро- in и degenerative, микроскопските necrobiotic, лезии в отделните inflammatory, тематични regenerative-adaptive, единици бяха използвани circulatory, над immunological 300 оригинални and авторски снимки. broilerneoplastic chickens, changes, 2013. leading Abstract to book, the correspondingXVIIIth World Veterinary deviations Poultry in the Congress,health status Nantes, of the France, organism. 19-23 ThisAugust, ensures 2013, the p.523 building of Поради това книгата намери ползотворен прием, както сред студенти, обучаващи се по ветеринарна медицина, така и сред колеги, занима- basic9. knowledge Dinev I. & S.and Denev, their 2013. application Clinical in and the morphological study of specific studies disease on spontaneous units in the cases special of Pseudomonas pathological aeruginosaanatomy. To infections illustrate in chickens. Abstract ващи се с диагностична и клинична ветеринарномедицинска практика. book,the macro- XVIIIth Worldand microscopic Veterinary Poultrylesions Congress,in each thematic Nantes, unit,France, more 19-23 than August, 300 original 2013, p.320 author‘s photographs were used. With this in mind, the book has found a fruitful reception, both among students studying 3. Динев, veterinary И., 2006.medicine Болести and amongпо птиците, colleagues Цветен атлас, I издание, engagedДРУГИ in diagnosticАВТОРСКИ and ИЗДАНИЯ clinical veterinary practice. изд. “Печатница 2М” ООД, Ст. Загора, 212 стр., ISBN: - 13: 978-954-9411- 07-2, (същият1. Динев, и на И. английски, 2014. Обща език). ветеринарна патология, учебник за сту- денти, 4.първо3. Dinev, Dinev, издание, I. I.,2007,2010. изд. Diseases. Diseases „Дъга+“, of of Poultry, Ст.Poultry, Загора, A A colour colourISBN: Atlas, 978-954-9387-84-1 II edition, ed., Atlas,Hardback, First2. edition, 208ppДинев, , ed.ISBN: И. “2M,2017. 978-954-9411-12-6 Print Обща House” ветеринарна Ltd, (същиятSt. Zagora, патология, и на руски Второ език) изд., 6. Dinev, I. & Y. Gardin, 2011. Enzootic outbreak and spontaneous regression of dermal squamous cell carcinoma in commercial layer hens. ISBN:”Дъга+” 978-954-9411-12-6 Целта ООД, на Стара тези Загора,издания ISBN: беше 978-619-7251-08-1 да създадем едно ръководство, което Abstract book, XVII World Veterinary Poultry Congress, Cancum, Mexico, 14-18 August, 2011, p.175 да е в услугаВажен4. Dinev, при момент диагностикатаI.,2010 при. създаванеDiseases на болеститеof наPoultry, книгата поA colourбеше птиците, не само както отразяване и да дава 7. Dinev, I. Leg weakness pathology in broiler chickens, 2012. 15th Biennial Congress of the International Society for Animal Clinical Pathology & Atlas,нанякои материята Second напътствия edition, „Обща за ed.,ветеринарнатяхната Hardback, профилактика патология“ 208pp, ISBN: и терапия.от гледна978- точка на нейния 14th Conference of the European Society of Veterinary Clinical Pathology, Ljubljana, Slovenia, from July, 3rd - 7th 2012, Proceedings, p.179 954-9411-12-6образователен Патологията (the характер sameна птиците andза студентиin еrussian изключително по and ветеринарна spanish, богата. Приблизителномедицина, а и 8. Dinev, I. 2013. Pathomorphological investigations on the incidence of axial skeleton pathology associated with posterior paralysis in commercial too)представянетона всекиhttp://uni-sz.bg/truni6/wp-content/uploads/vmf/ 4–5 годишен и откъм период страната се нарегистрира възможностите ново болестно на нейната състояние. диагно- broiler chickens, 2013. Abstract book, XVIIIth World Veterinary Poultry Congress,file/26.pdf Nantes, France, 19-23 August, 2013, p.523 стичнаВ делът стойност на инфекциозната във ветеринарномедицинската патология вероятна причина лабораторна за това и клинична може да 9. Dinev I. & S. Denev, 2013. Clinical and morphological studies on spontaneous Our casesprimary of Pseudomonas goal in the creation aeruginosa of this infections manual in chickens. Abstract практика.е голямата Отделните вариабилност тематични на етиологичният единици представяха агент. Макар възможности и на по-заден за book, XVIIIth World Veterinary Poultry Congress, Nantes, France, 19-23 August,wasплан, to 2013, неmake престава p.320 it helpful да се for допълва the diagnostics и обогатява of делътpoultry на неинфекциозните diseases,запознаване as well с основни as for their макро- treatment и микроскопски and prevention. лезии при дегенеративни, некробиотични,болести. В това числовъзпалителни, особена актуалност регенеративноприспособителни, през последните години цир до- ДРУГИ АВТОРСКИ ИЗДАНИЯ Avian pathology is very rich. A new disease is discovered кулаторни,биха патологията имунологични на скелетномускулната и неопластични система изменения, при бройлерни водещи до птици, съот- and identified1. Динев, at approximately И., 2014. Обща every ветеринарна 4 or 5 years. патология, The учебник за сту- ветнитемикотоксикозите, отклонения някои в здравния недоимъчни статус на състояния организма. и Това др. обезпечавашеБихме могли probableденти, първо cause издание,for this tendency изд. „Дъга+“, in infectious Ст. Загора, pathology ISBN: 978-954-9387-84-1 изграждане на основни знания и приложението им при изучаване на даспецифичните кажем, че неболестни намалява единици значимостта в специалната и на неопластичните патологична анатомия. болести. could be2. the Динев, high И.variability,2017. Обща of aetiological ветеринарна agents. патология, Второ изд., Заempyema, онагледяване 89 на макро- и микроскопските лезии в отделнитеhydrocephalus, тематичниИзползването единици 162, бяха на206 ваксини използвани срещу над Марекова 300 оригинални болест иавторски създаването снимки. на ге- Although”Дъга+” lessООД, significant, Стара Загора, the ISBN: group 978-619-7251-08-1 of non-infectious encephalitis,Поради това 184 книгата намери ползотворен прием, както средhydronephrosis, студенти,diseasesнетично обучаващи is alsoрезистентни 223 constantly се по ветеринарна линии enriched. птици, In медицина, значителноrelation to така them, редуцираха и сред колеги, загубите занима от- Hydropericardium,Важен момент113 при създаване на книгата беше не само отразяване ващиendocarditis, се с диагностична 119, 120, и клинична122, 123, ветеринарномедицинска132, 214 практика.theнеопластични pathology of заболявания, the musculoskeletal но в случаи system на избухванияin broiler щетите са значи- endometritis, 236, 237, hyperaemia,на материята 54, 55, „Обща 70, 73, ветеринарна 84, 119, 144, патология“ 165, 167, от 211, гледна точка на нейния chickens телни. 3. Тезиand Динев, обстоятелстваsome И. mycotoxicoses, 2006. налагат Болести acquiredподдържането по птиците, a special Цветен на високи атлас, нива I издание, знания enteritis, 30, 31, 32, 33, 37, 40, 41, 42, 43, 44, 80 212 образователен характер за студенти по ветеринарна медицина, а и importanceизд.и опит “Печатница от специалиститеfor the 2М”last ООД,few вyears. Ст.областта Загора, We can на 212 здравеопазванетоclaim стр., that ISBN: the - 13: 978-954-9411-на птиците. enterocolitis, 33, 165 hyperkeratinisation,представянето и25, откъм 27, 176,страната 177, 178на възможностите на нейната диагно- enteropathy, 39, 40, 42 hyperplasticsignificance07-2, Основен (същият enteritis, of похват neoplasticи на 44 английски в книгите diseases език).е използването is not reduced на too. снимков The материал пред- стична стойност във ветеринарномедицинската лабораторна и клинична enterotoxaemia, 32, 33 hyperthyroidism,usage вид ofтова, 4. vaccines Dinev, че 160,е най-лесно against I. 161,2010. Marek’s Diseasesдостъпният disease of Poultry, начин and the за A creation идентификацияcolour Atlas, II edition, на лезиите ed., практика. Отделните тематични единици представяха възможности за epidermitis serosa, 166 hypertrophy,ofHardback, приgenetically отделните 74, 208pp resistant129, нозологични , 224,ISBN: lines 251 978-954-9411-12-6 of единици.birds significantly Всички (същият снимки reduced и вна тeзи руски книги език) са ори- hypoplasia,запознаване 161, 162, с основни 231, 250 макро- и микроскопски лезии при дегенеративни, epidermoid cyst, 209 losses гинални caused Целта и са наby направени тезиneoplastic издания по diseases, времебеше да наyet създадем нашата the damages научноизследователска едно ръководство, което и epulis, 14 hypovitaminosisнекробиотични, E, 180, възпалителни, 181 регенеративноприспособителни, цир- causedдадиагностично е в byуслуга outbreaks при консултантска диагностиката are still heavy. дейност. на These болестите Всяко circumstances издание по птиците, на атласите както исъдържа да дава Erysipelothrix rhusiopathiae, 19, 122, 123 кулаторни, имунологични и неопластични изменения, водещи до съот- над 580 цветни фотоилюстрации, преобладаващо от които (над 500)I макроскопски.dictateнякои the напътствия maintenance Значително за тяхната of преимущественият a high профилактика level of knowledge дяли терапия. на and снимките, демонстри- exudative epidermitis, 166 experienceветните отклонения of specialists в здравнияin the field статус of avian на организма.health care. Това обезпечаваше ращи макроскопската патология при птиците, цели широко достъпното ползване Патологията на книгите. на Пакптиците в тази е връзка,изключително но същевременно богата. Приблизително с изтъкване изграждане The primary на основни approach знания of иinformation приложението presentation им при изучаванеused in this на book специфичните is the photographic болестни material, единици having в специалната in mind thatпатологична анатомия. диагностичнатаF стойност на хистологичното изследване при някоиichthyosis болести,на всеки еcongenita, сравнително 4–5 годишен 176, скромният 177 период брой се регистрира от микроскопски ново снимки.болестно състояние. Заit онагледяване is the most easily на макро- accessible и микроскопските way to identifying лезии lesions в отделните of the specificicterus, тематични nosologic56, единици 57, 71,units. 80,бяха All108, използваниphotos 187, in 188 this над book 300 areоригинални original and авторски снимки. В делът на инфекциозната патология вероятна причина за това може да madefatty Порадиinfiltration,during ourтова own книгата67, scientific224 намери and ползотворен consultation прием, work. както The atlasсредileus, студенти,contains 45, 46, обучаващиmore 48, than 49 580 се поcolour ветеринарна photographs, медицина, most такаof them, и сред колеги, занима- е голямата вариабилност на етиологичният агент. Макар и на по-заден ващиoverfibroadenoma, се500 с диагностична macroscopic. 245 Theи клинична predominant ветеринарномедицинска share of the photographs практика.infectious demonstrating epididymitis, the gross 247pathology of birds is aimed at the infectiousплан, rhinotracheitis, не престава да се82, допълва 84, 86, и обогатява89 делът на неинфекциозните comprehensionfibroma, 195, 196and user-friendliness of the book. In relation to this, and with the 3. Динев,purpose И.to ,put 2006. an emphasisБолести по on птиците, the diagnostic Цветен атлас, I издание, interstitialболести. pneumonia, В това число 102 особена актуалност през последните години до- 258 valuefibromyxosarcoma, of histological tests 110, for 199, some 231 diseases, is the relatively low numberизд. of microscopic “Печатница photographs. 2М” ООД, Ст. Загора, 212 стр., ISBN: - 13: 978-954-9411- fibropapilloma, 189, 190, 252 intestinalбиха emphysema, патологията на45 скелетномускулната система при бройлерни птици, invagination,07-2, (същият 47, 48 и на английски език). fibrosarcoma, 148, 196, 199 микотоксикозите, някои недоимъчни състояния и др. Бихме могли ischaemia, 131, 4. Dinev,176, 227 I.,2010. Diseases of Poultry, A colour Atlas, II edition, ed., fibrosation, 114, 131, 139, 140, 186, 219, 220, 222, 247 да кажем, че не намалява значимостта и на неопластичните болести. fluorosis, 8 Hardback, 208pp , ISBN: 978-954-9411-12-6 (същият и на руски език) J Използването на ваксини срещу Марекова болест и създаването на ге- follicular cyst, 240 Целта на тези издания беше да създадем едно ръководство, което нетично резистентни линии птици, значително редуцираха загубите от fowlpox (diphtheritic form), 9 да е в услуга при диагностиката на болестите по птиците, както и да дава fungi imperfecti, 173 Johne’sнеопластични disease, 44 заболявания, но в случаи на избухвания щетите са значи- някои напътствия за тяхната профилактика и терапия. телни. Тези обстоятелства налагат поддържането на високи нива знания K Патологията на птиците е изключително богата. Приблизително G и опит от специалистите в областта на здравеопазването на птиците. на всеки 4–5 годишен период се регистрира ново болестно състояние. keloid, 185 Основен похват в книгите е използването на снимков материал пред- gallstones, 71 В делът на инфекциозната патология вероятна причина за това може да ketosis,вид 68 това, че е най-лесно достъпният начин за идентификация на лезиите gangrenous mastitis, 243 е голямата вариабилност на етиологичният агент. Макар и на по-заден при отделните нозологични единици. Всички снимки в тeзи книги са ори- gangrenous pneumohia, 99, 100 L план, не престава да се допълва и обогатява делът на неинфекциозните gastritis, 19, 20, 23 гинални и са направени по време на нашата научноизследователска и болести. В това число особена актуалност през последните години до- gastroenteritis, 32 диагностично консултантска дейност. Всяко издание на атласите съдържа laryngitis,биха 85, патологията 86 на скелетномускулната система при бройлерни птици, надgingivitis, 580 цветни 8, фотоилюстрации,9, 10, 12, 14 преобладаващо от които (над 500) макроскопски. Значително преимущественият дял на снимките, демонстри- laryngotracheitis,микотоксикозите, 86, 87 някои недоимъчни състояния и др. Бихме могли ращиglioma, макроскопската 159 патология при птиците, цели широко достъпнотоLawsonia ползване intracellularis на книгите., 42 Пак в тази връзка, но същевременно с изтъкване glomerulonephritis, 211, 212, 219 да кажем, че не намалява значимостта и на неопластичните болести. диагностичната стойност на хистологичното изследване при някоиleiomyoma, болести, е сравнително 51, 240, 241 скромният брой от микроскопски снимки. granulomatous inflammation, 44, 146 leiomyosarcoma,Използването 202 на ваксини срещу Марекова болест и създаването на ге- leptospirosis, 56, 57, 58, 120, 144, 217, 218, 219, 232 H нетично резистентни линии птици, значително редуцираха загубите от leukoplakia,неопластични 11 заболявания, но в случаи на избухвания щетите са значи- leukosisтелни. enzootica Тези обстоятелства bovum, 74 налагат поддържането на високи нива знания haemangioma, 230 leukosis, 26, 52, 74, 75, 135, 141, 142, 143, 147, 230 haemangioma, 76, 134 lien lobatus,и опит от149 специалистите в областта на здравеопазването на птиците. haemangiopericytoma, 134 Linguatula Основенserata, похват83 в книгите е използването на снимков материал пред- haemangiosarcoma, 88, 110, 148 linguatulosis,вид това, 83 че е най-лесно достъпният начин за идентификация на лезиите haematomas, 119, 251 lipidosis,при 69 отделните нозологични единици. Всички снимки в тeзи книги са ори- haemoglobinuria, 57, 80, 232 lipoma,гинални 198 и са направени по време на нашата научноизследователска и haemolysis, 56, 187, 225, 232 liposarcoma, 197 haemopericardium, 118 liquefactiveдиагностично necrosis, консултантска 63, 152 дейност. Всяко издание на атласите съдържа надhaemorrhagic 580 цветни фотоилюстрации, cystitis, 232, 233 преобладаващо от които (над 500)listeriosis, макроскопски. 152, 153, Значително 154 преимущественият дял на снимките, демонстри- ращиhaemorrhagic макроскопската disease, патология 24, 161, при 211, птиците, 212 цели широко достъпнотоlithotherion, ползване 239 на книгите. Пак в тази връзка, но същевременно с изтъкване диагностичнатаhaemorrhagic стойност infarction, на хистологичното 47, 72, 109, 126 изследване при някоиlymphadenitis, болести, е сравнително 33, 138, скромният139, 141 брой от микроскопски снимки. haemorrhagic nephritis, 213 lymphangiosarcoma, 53 haemorrhagic pneumonia, 98, 99 lymphoid leukosis, 26, 52, 74, 75, 141, 142, 143, 147, 230 haemorrhagic septicaemia, 82 lymphoma, 135, 143 hepar moschatum, 55 hepatitis apostematosa, 62 M hepatitis, 56, 57, 58, 60, 61, 62, 63, 64, 65 Hermaphroditism, 241, 250, 252 mastocytoma, 149, 200 hexamitiasis, 30 melanoma, 76, 111, 195 254 hyalinisation, 180, 181, 213, 220, 222 melanosis maculosa, 70, 107, 143, 238 Изданията включват над 50 болести от областта на инфекциозната патология при птиците и призиблизително толкова от неинфекциозна- та. Освен класическите и добре познати сред колегията болести, тук попадат и някои сравнително нови, малко известни или неизвестни досега болестни състояния. Като такива бихме посочили холангиохепатит при бройлерите, някои усложнения след апликация на контаминирани ваксини с P. aeruginosa, хеморагичен ентерит при пуйките, известен атипизъм при някои неопластични болести и др. Като определено нови за птичата патология са включени състоянията на руптура сухожилието на m. gastrocnemius при родители за бройлери, руптура на a. renalis caudalis при пуйки и влияние семената на лепка (Galium aparine), върху здравословните и продуктивни показатели при бройлери. Уникален засега е представеният случай на хиперандрогенизъм при бройлери. Надяваме се, че тези издания имат своя принос за допълване на някои нови моменти в познанията и за убедителността на специали- стите в диагностицирането на птичите болести. Смятаме, че книгите намират ползотворен прием сред колеги ветеринарни лекари, студенти по ветеринарна медицина, фермери и изобщо специалисти в областта на птицевъдството. Изданията съществуват и в разширен електронен вариант, който би могъл да се ползва за обучение на специализанти и начинаещи колеги на базата на широки възможности за дискусия по разглежданите проблеми. 55.. Dinev,Dinev, I. ,I.,2009. 2009. Histopathology Histopathology and Cytology and of Cytology Poultry Diseases. of Poultry A Colour Diseases. Atlas, first A edition,Colour Atlas, fi rst edition,Imprimerie Imprimerie BM, France, Hardback, BM, France97pp. for B2B Consulting http://uni-sz.bg/truni6/wp-content/ uploads/vmf/fiСлед излизане le/27.pdf на книгите “Болести по птиците, цветен атлас”, за нас беше предизвикател- ство да направим едно по-дълбоко специализирано издание в тази област. Както вече отбеля- захме, After чрез publishing предходните ourкниги fi имахмеrst book, целта “a colourда представим atlas of в по-широкоPoultry diseases”, достъпен видour макроnext challenge- was toскопските produce лезии a more характеризиращи in-depth andотделни specialized болести и bookнасочващи on the към matter. решение Asза диагнозаwe noted, при the purpose патологоанатомично изследване. Целта на настоящата книга е да представим микроскопските ofлезии our на fi тъканно rst book или клетъчноwas to ниво,present, имащи in диагностичнаa broader стойностand more за доказване accessible на определениway, the macroscopic lesions,болестни състоянияcharacterizing при птиците. specifi c diseases and directing towards a specifi c diagnosis in a pathoanatomicalКнигата е структурирана study. The чрез aim раздели of the на current база етиологичен book is toпринцип, present считайки the microscopic това за lesions onудобство tissue при or лабораторната cellular level диагностика that have на aптичите diagnostic болести. value Основен for похват detection е демонстрация of specifi на c diseases in birds.лезиите The чрез book снимков is divided материал. into Съдържа units on общо an 214etiological цветни фотоилюстрации. basis, with the Всички idea снимки of more в convenient laboratoryтази книга са diagnosticsоригинални и саof направениpoultry diseases. по време на All нашата images научноизследователска are original and иobtained диагнос- during our researchтично консултантска and diagnostic дейност. consultant activities. The demonstratedДемонстрираните lesions лезии на onцитологично the cytological ниво имат levelпредназначение are relevant за насочване for the към quick бър- diagnostics за диагностика при някои болести по птиците, като неопластичните болести, някои клостридиози и др. Хистологичните лезии освен в диагностиката,of some биха poultry могли даillnesses, се имат предвидsuch as и neoplasticза разбиране diseases,хистогенезата some в механизма clostridioses, на болестта. etc. Apart from diagnostics,Разбира се, при theчаст отhistological птичите болести lesions структурните can be лезии taken имат into решаваща consideration диагностична for стойност,the understanding при друга допълваща. of the Решаваща disease’s диагно histogenesis- and mechanism.стична стойност Ofимат course, цитологичните for some и хистопатологични diseases in birds, изменения structural при неопластичните lesions have болести, a decisive някои вирусни diagnostic болести value, с включения while (адено for others- - only complementary.вирусни, ларинготрахеит We и hopeдр.), инфекциозен that the currentенцефаломиелит publication и др. В болшинствотоwill be readily от останалите accepted случаи by същносттаavian pathologists на хистопатологичното working и in the fi eld ofцитологично laboratory изследване diagnostics е доказване of poultry на допустима disease, диагноза as well въз основа as by на veterinary констатирани professionals макроскопски лезии. and students interested in this aspect of pathology.Имаме основание да смятаме, че изданието се приема добре сред колегите лабораторни лекари, работещи върху диагностиката на боле- сти по птиците, както и от ветеринарни специалисти и студенти, имащи интерес към този аспект на патологията. 6. Dinev, I.,2014. Ceva handbook of poultry 6.diseases, Dinev, I. ,2014.fi rst Cevaedidion, handbook volume of poultry I. diseases,Graphic design and IVAN DINEV & CEVA IVAN DINEV & CEVA volume I, Graphic design and printing: A,A les points sur les A, IVAN DINEV & CEVA IVAN DINEV & CEVA France,printing: ISBN: 979-10-92450-01-9 Ȧ,Ȧ les points sur les A, France, ISBN: 979- 7.10-92450-01-9; Dinev, I.,2014. Ceva EAN handbook 9791092450019, of poultry diseases, hardcover, pages volume197. II, http://uni-sz.bg/truni6/wp-content/uploads/vmf/Graphic design and printing: A,A les points sur les A, France,fi le/28.pdf ISBN: 979-10-92450-02-6 Ceva HaND book Ceva HaND book Тези книги7. представляват Dinev, I.,2014 поредни. изданияCeva handbook в областта of poultry Volume 1 Cevaof poultry HaND D bookiseases Volume 2Cevaof poultry HaND book Diseases Volume 1 of poultry Diseases Volume 2 of poultry Diseases но болестиdiseases, по птиците. fi rst Следedidion, публикуване volume на първоII. Graphic и вто- design and ро изданиеprinting: на книгите Ȧ,Ȧ “Diseasesles points of Poultry. sur les A Colour A, France, Atlas” и ISBN: 979- “Histopathology10-92450-02-6; and Cytology EAN of 9791092450026, Poultry Diseeases”, целта hardcover, на pages този200. труд еhttp://uni-sz.bg/truni6/wp-content/uploads/vmf/ да предложи ръководства, които предоставят повече теоретически и същевременно практически не- GUMBORO NEWCASTLE DISEASE SAlmoNElloSIS mYCoPlASmA GAllISEPTICUm INFECTIoNS GUMBOROCHICKEN AN AEMIA NEWCASTL AVIAN INFLUENZAE DISEASE SAlmoNE CAllomPYSISlo BACTERIoSIS m YCoPlAS mmYCA oGAPlllASISEPTICUmA SYNmo VIAEINFECTI INFECTIoNS oNS fi le/29.pdf CHICKENREOVIRUS AN AEMIA AVIAN INFECTIOUS INFLUENZA BRONCHITIS CAmPY lo FowlBACTERI CholoSISERA mYCoPlAS INFECTImA SYNooUSVIAE Co INFECTIRYZA oNS REOVIRUSMAREK INFECTIOUS LARYNGOTRACHEITIS BRONCHITIS Fowl C hol AVIANERA C loSTRIDIoSIS INFECTI o USFowl CoRYZA PoX обходими данни по един лесно достъпен начин за някои MAREKRUNTING-STUNTING LAR AVIANYNGOTRACHEITIS AVIAN C loCoSTRIDICCIDIooSISSIS Fowl Po X E GG DRoP SYNDRomE’ 1976 RUNTING-STUNTINGSYNDROME AVIANMETAPNEUMOVIRUS CoCCIDIoSIS EGG DRoP SYNDRomE’ 1976 This books represent a series of similar SYNDROME METAPNEUMOVIRUS болести по птиците. Разработениpublications и представени based on са the теми idea в областта of Seva на неоSanté- Animalе. Followingпластичните theболести, publishing респираторните of the болести,fi rst and имуносупресивни second editions състояния, of the болестиbooks във“Diseases връзка сof публичното Poultry. здраве,A Colour ентеритни Atlas” andболести “Histopathology andи някои Cytology други. of Poultry Diseases,” the aim of this work is to off er a handbooks, which provide more practically oriented data about someВсяка poultry тема diseasesвключва данни in a заmore история comprehensible на болестта, характеристика way. The иdevelopment класификация наand патогена, presentation епидемиология, of topics клинични in the признаци fi elds и of neoplastic diseases,патология, диагностикаrespiratory и диференциалнаdiseases, immunosuppressive диагноза, мониторинг agents, и превенция. poultry Макроскопските, diseases and микроскопските public health, лезии enteric и клиничните diseases признаци and some others haveпри разработените been planned. нозолигични Each topic единици will саinclude илюстрирани data about чрез богат the снимков history материал,of the disease, добит по characteristics време на нашата and диагностична, classifi cation научноиз of the- pathogen, epidemiology,следователска и консултантска clinical signs дейност. and pathology, diagnosis and monitoring, prevention and vaccinology. Gross and microscopic lesions, as wellНадяваме as the се, clinical че книгите signs представляват of included лесни nosological и удобни заunits ползване will beръководства illustrated в областта through на aпатологията rich collection на птиците of photos, от студенти, produced начи- during our diagnostic,наещи лекари research и професионалисти. and consultation activities.

8. Ivan Dinev & Guillermo González García, 2018. Gastrointestinal Disorders of Poultry, fi rst edition, volum 1. Printing: PDF 33 – Bordeaux, France. ISBN 979- 10-92450-03-3, EAN 9791092450033 http://uni-sz.bg/ truni6/wp-content/uploads/vmf/fi le/GDP-HANDBOOK- volume1-spe.pdf 9. Ivan Dinev, 2018. Gastrointestinal Disorders of Poultry, fi rst edition, volum 2. Printing: PDF 33 – Bordeaux, France. ISBN 979-10-92450-04-0, EAN 9791092450040 http://uni-sz.bg/ The present editions includes more than 30 disease conditions aff ecting the gastrointestinal tract in poultry of the meat and egg production type. They are divided into sections on the grounds of etiological causes: bacterial, parasitic, mycoses and mycotoxicoses, and metabolic and nutritional. Each section presents up-to-date health problems in contemporary poultry farming with their prevalence, etiology, clinical signs and lesions, diagnostics and diff erential diagnostics, possibilities for treatment and prevention, as well as attempts to control. 259 SOME AUTHORIAL REFLECTIONS (Logical reflections resulting from personal experiences and synthesis) 1. The engine of life – being optimistic about the future while not forgetting the realities of today.

2. True victory is avoiding the war altogether, not winning it (all wars have casualties). 3. Knowing your history is the best basis for your future. There is no other way to understand the present if you do not know the past. 4. Only those who know their history can understand where they are now and where they can get. 5. Did God create mortals, or did mortals create God? 6. Even the most important thing in the Heavens derives from Earth! 7. A person’s biography may consist of thousands of positive aspects but if there is a single negative one, it is typically a highly distinguishing characteristic. 8. Reputation – a reflection of style and constants of faith and love. 9. My wisest insight – realizing how stupid I am. Everything else is dependent on this. 10. The biggest human frailty – greed. 11. The biggest deception – self-pity. 12. What makes me human – being considerate of other people. 13. What makes me a professional – striving for development and refinement for the benefit of everybody else in my field. 14. Work – the thing that can inspire me, help me develop, or save me. 15. If I am noticeable, it means that I exist. 16. Indolence does not kill a person but it prevents him or her from prospering (a reflection bequeathed by my mother). 17. One of the key skills necessary to focus on your work is the ability to disregard all irritations. 18. The path to success often involves walking along the razor’s edge. 19. Shrewdness – the ability to invest the appropriate knowledge and resources into a particular project. 20. My biggest satisfaction – accomplishing the projects of my convictions and potential. 21. My motivation – the conviction that I am obliged to leave a heritage consisting of everything that I am capable of, with the hope that this will fulfil my life’s mission.

empyema,22. The 89 way you present yourself is unique and nobody else canhydrocephalus, do it for you – consciously 162, 206 or unconsciously. encephalitis,23. Provincialism 184 – a powerful inhibitor of intellectual progress.hydronephrosis, 223 endocarditis, 119, 120, 122, 123, 132, 214 Hydropericardium, 113 endometritis,24. To my sons236, – 237, do not feel indebted to me. The hope that youhyperaemia, will pass on the 54, encoded 55, 70, uniqueness 73, 84, 119,of our 144, family 165, into 167, the 211, future enteritis,makes 30, me 31, indebted 32, 33, to 37, you 40, – forever! 41, 42, 43, 44, 80 212 enterocolitis, 33, 165 hyperkeratinisation, 25, 27, 176, 177, 178 enteropathy,25. God is 39,reason 40, (addressed 42 to my sons). hyperplastic enteritis, 44 enterotoxaemia, 32, 33 hyperthyroidism, 160, 161 26. Sixty years are not enough to enjoy what the world has to offer – but still too little to do all the things that you are capable of. epidermitis serosa, 166 hypertrophy, 74, 129, 224, 251 epidermoid27. My professionalcyst, 209 and personal experiences allow me to reachhypoplasia, the conclusion 161, that 162, for 231, every 250 work, the ability to use not only epulis,your 14 brain - but also your heart - is a key catalyst for progress.hypovitaminosis E, 180, 181 Erysipelothrix rhusiopathiae, 19, 122, 123 exudative epidermitis, 166 I F ichthyosis congenita, 176, 177 icterus, 56, 57, 71, 80, 108, 187, 188 Epilogue: A world with no pathology wouldileus, 45,be 46,wonderful. 48, 49 In fact, if pathol- fatty infiltration,ogy did 67, 224not exist, there would be no need for medicine at all (possible to fibroadenoma, 245 infectious epididymitis, 247 fibroma, 195,interpret 196 in different ways). Pathology involves,infectious andrhinotracheitis, continues 82, to 84,involve, 86, 89 significant amounts of human resourcesinterstitial inpneumonia, the name 102 of life. 260 fibromyxosarcoma, 110, 199, 231 fibropapilloma, 189, 190, 252 intestinal emphysema, 45 fibrosarcoma, 148, 196, 199 invagination, 47, 48 fibrosation, 114, 131, 139, 140, 186, 219, 220, 222, 247 ischaemia, 131, 176, 227 fluorosis, 8 follicular cyst, 240 J fowlpox (diphtheritic form), 9 fungi imperfecti, 173 Johne’s disease, 44 G K