Actinomycosis Israeli, 129, 352, 391 Types Of, 691 Addison's Disease, Premature Ovarian Failure In, 742

Total Page:16

File Type:pdf, Size:1020Kb

Actinomycosis Israeli, 129, 352, 391 Types Of, 691 Addison's Disease, Premature Ovarian Failure In, 742 Index Abattoirs, tumor surveys on animals from, 823, Abruptio placentae, etiology of, 667 828 Abscess( es) Abdomen from endometritis, 249 ectopic pregnancy in, 6 5 1 in leiomyomata, 305 endometriosis of, 405 ovarian, 352, 387, 388-391 enlargement of, from intravenous tuboovarian, 347, 349, 360, 388-390 leiomyomatosis, 309 Acantholysis, of vulva, 26 Abdominal ostium, 6 Acatalasemia, prenatal diagnosis of, 714 Abortion, 691-697 Accessory ovary, 366 actinomycosis following, 129 Acetic acid, use in cervical colposcopy, 166-167 as choriocarcinoma precursor, 708 "Acetic acid test," in colposcopy, 167 criminal, 695 N-Aceryl-a-D-glucosamidase, in prenatal diagnosis, definition of, 691 718 of ectopic pregnancy, 650-653 Acid lipase, in prenatal diagnosis, 718 endometrial biopsy for, 246-247 Acid phosphatase in endometrial epithelium, 238, endometritis following, 250-252, 254 240 fetal abnormalities in, 655 in prenatal diagnosis, 716 habitual, 694-695 Acridine orange fluorescence test, for cervical from herpesvirus infections, 128 neoplasia, 168 of hydatidiform mole, 699-700 Acrochordon, of vulva, 31 induced, 695-697 Actinomycin D from leiomyomata, 300, 737 in therapy of missed, 695, 702 choriocarcinoma, 709 tissue studies of, 789-794 dysgerminomas, 53 7 monosomy X and, 433 endodermal sinus tumors, 545 after radiation for cervical cancer, 188 Actinomycosis, 25 spontaneous, 691-694 of cervix, 129, 130 pathologic ova in, 702 of endometrium, 257 preceding choriocarcinoma, 705 of fallopian tube, 352 tissue studies of, 789-794 of ovary, 390, 391 threatened, 694 of vagina, 2 57 tissue studies of, 789-794 Actinomycosis israeli, 129, 352, 391 types of, 691 Addison's disease, premature ovarian failure in, 742 863 Index Adenocanthomas Adenomyosis, 312-315, 405 ectopic tissue of, in ovarian neoplasms, 589 in animals, 811, 814, 815, 841 in animals, 810 tumors of, Sertoli-Leydig cell tumors and, 517 of endometrium, 281, 290, 292 clinical aspects of, 312-313 Adrenarche, effect on external genitalia, 13 of fallopian tube, 361 conditions associated with, 314-315 ,8-Adrenergic receptor stimulants, leiomyoma of ovary, 479, 481, 482 gross appearance of, 313 induction by, 801 Adenocarcinofibroma, of ovary, 468 histogenesis, 314 Adrenogenital syndrome, 402 Adenocarcinoma( s) leiomyomata and, 300, 301 as cause of pseudohermaphroditism, 10, 16 in animals microscopy of, 313-314 prenatal detection of, 714 induced, 801, 809, 810, 811, 812, 814, 815 of uterus, 353, 774 African lymphoma, see Burkitt's lymphoma spontaneous, 809, 824-831, 834, 836, 841, Adenosarcomas, experimental induction of, in AG-4 antibody, in cervical cancer detection, 187 845, 849, 853, 856 animals, 804 Agouti, genital tract tumors in, 827, 837 of Bartholin gland, 46, 51 Adenosis, of vagina, after DES exposure, 100 Albinism, of vulva, 35 of breast, Paget's disease in, 44-45 Adenosquamous carcinoma Alcian blue stain in cervical endometriosis, 141 of cervix, 190, 196 for mast cells, 301 of cervix, 70, 87-101, 122, 139, 180, 189-196 of endometrium, 292-294 for mucin, 27, 190, 296 cytology, 760-761 of fallopian tube, 361 Aldosteronism, with ovarian neoplasms, 587 differential diagnosis, 125, 126, 131, 133, in mixed mesodermal tumors, 554 Alkaline phosphatase 134, 140 Adenovirus infection, cytological identification of, in dysgerminomas, 532 in polyps, 132 755 in endometrial epithelium, 238-240 cytological detection of, 764-766 Adenyl cyclase, in endometrium, estradiol effects in irradiated cervical cells, 198 of endocervix, 761 on, 241-242 method using, in embryological studies, 1 in endometrial polyp, 2 59 Adhesions stains for, in spiral arteriole studies, 214 of endometrium, 198-199, 202, 270, 276, 278- amniochorionic, 784-786 Alky lacing agents 292, 761 from endometriosis, 409 cytological effects of, 763 cytology, 764 infertility from, 739, 740-741 in ovarian cystadenoma therapy, 472 of fallopian tube, 359-361 tubal, in endosalpingiosis, 355 Allantois, 1, 2 cytology, 765-766 Adipic acid, vaginal lesions induced by, 813 Alloisoleucine, in prenatal detection, 717 metastases of, 51 Adipose tissue, in myometrial mesodermal tumors, Alsatian dog, ovarian tumors in, 849, 850, 851, in mixed mesodermal tumor, 554, 560 316, 317 853 of ovary, 414 Adolescents Alveolar-glandular pattern, of endodermal sinus from prenatal exposure to DES, 87-101, 813 choriocarcinomas in, 594-595 tumors, 542 with sarcoma, 323, 336. (See also Mullerian clear cell adenocarcinomas in, 88 Amebiasis, of cervix, 129 tumors) dysgerminomas in, 529, 589-592 Ameboid movement, of primordial germ cells, 2 tuberculous salpingitis and, 351 embryonal carcinomas in, 592-593 Amenorrhea of vagina, 87-101, 813 endodermal sinus tumors in, 539, 594 in Asherman's syndrome, 256 of vulva, 31, 32, 51 epithelial neoplasms in, 606-611 in congenital adrenal hyperplasia, 448 Adenofibroma. (See also Adenomyomas, external genitalia changes in, 13-14 from dysgerminomas, 5 29 Lymphangiomas) Leydig (hilus) cell tumors in, 615 (!estrogen carcinoma" with, 276 papillary malignant lymphomas in, 616-619 after oral contraceptive use, 262 of cervix, 131, 139-140 ovarian cysts in, 618-621 from premature ovarian failure, 741-742 of ovary, 454, 455, 467-469 ovarian tumors in, 586-626 from Sertoli-Leydig cell tumors, 517 Adenofibromyomas in animals, 810 ovary of, 384, 398, 779 in Stein-Leventhal syndrome, 399, 401 Adenoid cystic carcinoma, of cervix, 190, 196-197 sarcomas in, 616-617 in tuberculous endometritis, 256 "Adenoma malignum," of cervix, 191-193 sclerosing stromal tumors in, 614, 615 vaginal smear cytology of, 769-770 Adenomas, in animals, 806, 809, 824, 828, 831, Sertoli cell tumors in, 613 X-chromosome abnormalities in, 438, 440-442 833, 835, 836, 838, 846, 853 Sertoli-Leydig cell tumor in, 615-616 Amino acids, errors of metabolism of, prenatal Adenomatoid tumors. (See also Lymphangioma) sex cord-stromal tumors in, 611-616 diagnosis, 713-718 of ovary, 454, 497 teratoblastomas in, 592-593 Aminoazotolune, ovarian tumor induction by, in ~~Adenomatosis," see Adenosis teratocarcinomas in, 595-597 animals, 801 Adenomatous hyperplasia, 265, 267-271, 282, 286 teratomas in, 552-553, 554, 597-600 Ammonia, in prenatal diagnosis, 716 in animals, 825 thecomas in, 613-614 Amniocentesis, 656, 711 arypical, 270, 273 Adrenal cortex, hyperactivity of, animal tumors early, 713-718 as carcinoma precursor, 267 and, 810 predelivery, 718-724 Adenomyomata Adrenal cortical hyperplasia technique of, 712 adenomyosis and, 313 congenital, female pseudohermaphroditism and, Amniochorionic adhesions, gross examination of, in animals, 827 447-448 784-786 of cervix, 131, 140 endocrine disorders from, 402 Amniochorionic roll, for fetal membrane experimental induction of, in animals, 802 endometrial carcinoma and, 279 sectioning, 788 of fallopian tube, 356 male pseudohermaphroditism and, 447 Amniography, of hydatidiform mole, 703 occurrence of, 307 Adrenal gland Amnion 864 Index bacterial infections of, 659, 660 prenatal detection of, 713 of vagina, 61 formation of, 639, 655 Angiokeratoma, of vulva, 29 Arteriography, of hydatidiform mole, 703 nodosum, 656, 658, 659, 786 Angiomyolipoma, of myometrium, 316 Arylsulfatase A, in prenatal diagnosis, 717 rupture of, fetal abnormalities and, 656 Angiomyomas, 306 Ascaris lumbricoides, in cervico-vaginal smears, 755 Amnion bands, fetal abnormalities and, 656 Angiosarcomas Ascites Amnion cells, 656 hemangiopericytomas and, 311 from embryonal carcinoma, 592 Amniotic fluid of uterus, 323 from granulosa cell tumors, 612 abnormalities of, 656 of vulva, 51 from ovarian tumors, 587 biochemical assays of, 710-733 Angora rabbits, genital tract tumors in, 832 Asherman's syndrome indications for, 711 Animal models, for ovarian and uterine tumors, endometritis in, 254, 256 interferences in, 712 797-82'1 infertility from, 737 sample handling in, 712 Animals. (See also individual animals) Aspartic amino transferase, in endometrial time dependent factors in, 711-712 genital tract tumors in, 797-861 epithelium, 238 creatine phosphokinase in, as fetal death Annular tubules, in sex cord tumors, 524, 574 Aspergillus, endometrial infection by, 256 indicator, 712-713 Anovulation "Atherosis" lesions, in abnormal uteroplacental embolism from, 662 dysfunctional uterine bleeding from, 261-262 vasculature, 687-688 leakage of, in placental abnormalities, 664 endometrial hyperplasia from, 265, 266 Atrophic vulvitis, 36 origin of, 711 Antelope, genital tract tumors in, 827 Auspitz sign, in psoriasis, 26 volume of, 712 Antibodies Autoimmunity, in premature ovarian failure, Amniotic sac, distension by water, for gross autoimmunity from, in premature ovarian 741-742 inspection, 785 failure, 742 Autosomal chromosomes, abnormalities of, 440- Amnionitis, causes and effects of, 659 to sperm 442 Ampulla, of fallopian tube, 341, 342 infertility from, 735 Axilla, endometriosis of, 405 Amylo-1,6-glucosidase from schistosomiasis, 129 Azygous artery, 61 in cervical parabasal cells, 104 Antigen TJ a, habitual abortion and, 692 in prenatal diagnosis, 715 Antigens, cervical stimulation by, 110 Anaerobic glycolysis Aortic lymph nodes, 368, 369 Backache, from cervicitis, 124 in endometrial epithelium, 240 metastatic cancer of, 290, 328 Bacterial endocarditis, amnion infections by, 659 in malignant cells, 183 Apocrine glands Bacteroides Anaphase lag, mosaicism from, 424, 427, 433, 436 disorders of, 25, 28, 29 in puerperal endometritis, 250 Anatomy of vulva, 14, 15 in salpingitis etiology, 347 of cervix, 102-123 Appendicitis, oophoritis and, 387 Balanitis xerotica obliterans, 40 of fallopian tube,
Recommended publications
  • Male Reproductive System Sexual Reproduction Requires Two Types Of
    Male Reproductive system Sexual reproduction requires two types of gametes or sex cells. In the male these cells are the spermatozoa and in the female they are the ova. The reproductive systems are unique in three respects 1. They are specialized in perpetuating the species and passing genetic information. 2. The anatomy and physiology between the male and female reproductive systems are different. 3. They exhibit latent development under hormonal control. The structures of the male reproductive system can be divided into three categories. 1. Primary sex organs - the gonads (testes). These produce sperm and sex hormones. 2. Secondary sex organs - the structures necessary for caring for and transportation of the sperm. A. Sperm transporting ducts 1. epididymus 2. ductus deferens 3. ejaculatory ducts 4. urethra B. Accessory glands 1. seminal vesicle 2. prostate gland 3. bulbourethral (Cowper's) glands C. Copulatory organ - penis. Also includes the scrotum (the skin enclosing the testes) 3. Secondary sex characteristics - These are not reproductively necessary, but are considered sexual attractants. They include things such as body hair, body physique, and voice pitch. Sexual determination - Sex is determined at the time of conception. As we will see, all ova have an x chromosome and sperm are 50:50 X and Y. If an ova is fertilized by an x sperm then we have a female. If an ova is fertilized by a Y sperm then we have a male. Sometimes we see more than one X in an ovum. As long as there is a Y chromosome we will have a male. ie. XXXY = male.
    [Show full text]
  • The Morphology, Androgenic Function, Hyperplasia, and Tumors of the Human Ovarian Hilus Cells * William H
    THE MORPHOLOGY, ANDROGENIC FUNCTION, HYPERPLASIA, AND TUMORS OF THE HUMAN OVARIAN HILUS CELLS * WILLIAM H. STERNBERG, M.D. (From the Department of Pathology, School of Medicine, Tulane University of Louisiana and the Charity Hospital of Louisiana, New Orleans, La.) The hilus of the human ovary contains nests of cells morphologically identical with testicular Leydig cells, and which, in all probability, pro- duce androgens. Multiple sections through the ovarian hilus and meso- varium will reveal these small nests microscopically in at least 8o per cent of adult ovaries; probably in all adult ovaries if sufficient sections are made. Although they had been noted previously by a number of authors (Aichel,l Bucura,2 and von Winiwarter 3"4) who failed to recog- nize their significance, Berger,5-9 in 1922 and in subsequent years, pre- sented the first sound morphologic studies of the ovarian hilus cells. Nevertheless, there is comparatively little reference to these cells in the American medical literature, and they are not mentioned in stand- ard textbooks of histology, gynecologic pathology, nor in monographs on ovarian tumors (with the exception of Selye's recent "Atlas of Ovarian Tumors"10). The hilus cells are found in clusters along the length of the ovarian hilus and in the adjacent mesovarium. They are, almost without excep- tion, found in contiguity with the nonmyelinated nerves of the hilus, often in intimate relationship to the abundant vascular and lymphatic spaces in this area. Cytologically, a point for point correspondence with the testicular Leydig cells can be established in terms of nuclear and cyto- plasmic detail, lipids, lipochrome pigment, and crystalloids of Reinke.
    [Show full text]
  • Intraligamentous and Retroperitoneal Tumors of the Uterus and Its Adnexa
    INTRALIGAMENTOUS AND RETROPERITONEAL TUMORS OF THE UTERUS AND ITS ADNEXA. BY WILLIAM H. WAT HEN. A. M.. M. D. [Reprinted from the 1894 Transactions of the American Gynecological Society.] INTRALIGAMENTOUS AND RETROPERITONEAL TUMORS OF THE UTERUS AND ITS ADNEXA. BY WILLIAM H. WATHEN. A. M.. M. D„ Professor of Abdominal Surgery and Gynecology in the Kentucky School of Medicine; Fellow of the American Gynecological Society and of the Southern Surgical and Gynecological Society; Gynecologist to the Kentucky School of Medicine Hospital and the Louisville City Hospital, etc., Louisville, Kentucky. With two Illustrations. A few years ago paroophoritic cysts embedded between the layers of the broad ligament deep into the pelvic cellular tissue, and intraligamentous and retroperitoneal myomata of the uterus or its muscular processes, were not amenable to surgical treat- ment, and when such conditions were encountered in a celiotomy the abdomen was closed without attempting to remove the tumor. Fortunately we now know more about the pathology of these tumors, and have learned how they may be removed with less mortality than was usual twenty years ago in ovariotomy. Paroophoritic cysts and subperitoneal myomata have nothing in common in their etiology, but, as the technique of the operation for their successful removal is in many particulars identical, I will include both kinds of tumors in what 1 will say to-day. Alban Doran, J. Bland Sutton, and other authorities have recently written so much about the pathology of these tumors that it will not be necessary for me to consider that part of the subject further than to make intelligent what I will say about the operative treatment.
    [Show full text]
  • Germline Fumarate Hydratase Mutations in Patients with Ovarian Mucinous Cystadenoma
    European Journal of Human Genetics (2006) 14, 880–883 & 2006 Nature Publishing Group All rights reserved 1018-4813/06 $30.00 www.nature.com/ejhg SHORT REPORT Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma Sanna K Ylisaukko-oja1, Cezary Cybulski2, Rainer Lehtonen1, Maija Kiuru1, Joanna Matyjasik2, Anna Szyman˜ska2, Jolanta Szyman˜ska-Pasternak2, Lars Dyrskjot3, Ralf Butzow4, Torben F Orntoft3, Virpi Launonen1, Jan Lubin˜ski2 and Lauri A Aaltonen*,1 1Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland; 2International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland; 3Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark; 4Pathology and Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland Germline mutations in the fumarate hydratase (FH) gene were recently shown to predispose to the dominantly inherited syndrome, hereditary leiomyomatosis and renal cell cancer (HLRCC). HLRCC is characterized by benign leiomyomas of the skin and the uterus, renal cell carcinoma, and uterine leiomyosarcoma. The aim of this study was to identify new families with FH mutations, and to further examine the tumor spectrum associated with FH mutations. FH germline mutations were screened from 89 patients with RCC, skin leiomyomas or ovarian tumors. Subsequently, 13 ovarian and 48 bladder carcinomas were analyzed for somatic FH mutations. Two patients diagnosed with ovarian mucinous cystadenoma (two out of 33, 6%) were found to be FH germline mutation carriers. One of the changes was a novel mutation (Ala231Thr) and the other one (435insAAA) was previously described in FH deficiency families. These results suggest that benign ovarian tumors may be associated with HLRCC.
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2015/0353527 A1 Zisman (43) Pub
    US 20150353527A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2015/0353527 A1 Zisman (43) Pub. Date: Dec. 10, 2015 (54) NON-SELECTIVE KINASE INHIBITORS Publication Classification (71) Applicant: arence ZIAMAN, Slingerlands, NY (51) Int. Cl. (US) C07D 40/12 (2006.01) (72) Inventor: Lawrence S Zisman, Slingerlands, NY C07D 24/20 (2006.01) (US) C07D 403/2 (2006.01) (73) Assignee: PULMOKINE, INC. Slingerlands, NY (52) U.S. Cl. (US) CPC ............ C07D401/12 (2013.01); C07D 403/12 (21) Appl. No.: 14f76O139 (2013.01); C07D 241/20 (2013.01) y x- - - 9 (22) PCT Filed: Jan. 9, 2014 (57) ABSTRACT (86). PCT No.: PCT/US1.4/10778 T.S. ). L. 9, 2015 Disclosed herein are compounds, compositions, and methods e 19 for preventing and treating proliferative diseases associated Related U.S. Application Data with aberrant receptor tyrosine kinase (RTK) activity. The (60) Provisional application No. 61/751.217, filed on Jan. therapeutic indications described herein more specifically 10, 2013, provisional application No. 61/889,887, relate to the non-selective inhibition of RTKs associated with filed on Oct. 11, 2013. vascular and pulmonary disorders. Patent Application Publication Dec. 10, 2015 Sheet 1 of 26 US 2015/0353527 A1 FIG. 1A $: 8:3 $38: Coacentration (nM) FG, B C s C am u was e D 9 9 A. Concentration (nM) Patent Application Publication Dec. 10, 2015 Sheet 2 of 26 US 2015/0353527 A1 F.G. 1 C Concentration (in M) F.G. 1D c C R sa spagh d g e d A. :::::: Concentration (in M) Patent Application Publication Dec.
    [Show full text]
  • Mechanisms of Gonadal Morphogenesis Are Not Conserved Between Chick and Mouse ⁎ Ryohei Sekido , Robin Lovell-Badge
    Developmental Biology 302 (2007) 132–142 www.elsevier.com/locate/ydbio Mechanisms of gonadal morphogenesis are not conserved between chick and mouse ⁎ Ryohei Sekido , Robin Lovell-Badge Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK Received for publication 3 June 2006; revised 16 August 2006; accepted 5 September 2006 Available online 9 September 2006 Abstract To understand mechanisms of sex determination, it is important to know the lineage relationships of cells comprising the gonads. For example, in mice, the Y-linked gene Sry triggers differentiation of Sertoli cells from a cell population originating in the coelomic epithelium overlying the nascent gonad that also gives rise to uncharacterised interstitial cells. In contrast, little is known about origins of somatic cell types in the chick testis, where there is no Sry gene and sex determination depends on a ZZ male/ZW female mechanism. To investigate this, we performed fate mapping experiments in ovo, labelling at indifferent stages the coelomic epithelium by electroporation with a lacZ reporter gene and the underlying nephrogenous (or mesonephric) mesenchyme with chemical dyes. After sex differentiation, LacZ-positive cells were exclusively outside testis cords and were 3βHSD-negative, indicating that the coelomic epithelium contributes only to non-steroidogenic interstitial cells. However, we detected dye-labelled cells both inside and outside the cords. The former were AMH-positive while some of the latter were 3βHSD- positive, showing that nephrogenous mesenchyme contributes to both Sertoli cells and steroidogenic cells. This is the first demonstration via lineage analysis that steroidogenic cells originate from nephrogenous mesenchyme, but the revelation that Sertoli cells have different origins between chick and mouse suggests that, during evolution, mechanisms of gonad morphogenesis may diverge alongside those of sex determination.
    [Show full text]
  • ANA214: Systemic Embryology
    ANA214: Systemic Embryology ISHOLA, Azeez Olakune [email protected] Anatomy Department, College of Medicine and Health Sciences Outline • Organogenesis foundation • Urogenital system • Respiratory System • Kidney • Larynx • Ureter • Trachea & Bronchi • Urinary bladder • Lungs • Male urethra • Female urethra • Cardiovascular System • Prostate • Heart • Uterus and uterine tubes • Blood vessels • Vagina • Fetal Circulation • External genitalia • Changes in Circulation at Birth • Testes • Gastrointestinal System • Ovary • Mouth • Nervous System • Pharynx • Neurulation • GI Tract • Neural crests • Liver, Spleen, Pancreas Segmentation of Mesoderm • Start by 17th day • Under the influence of notochord • Cells close to midline proliferate – PARAXIAL MESODERM • Lateral cells remain thin – LATERAL PLATE MESODERM • Somatic/Parietal mesoderm – close to amnion • Visceral/Splanchnic mesoderm – close to yolk sac • Intermediate mesoderm connects paraxial and lateral mesoderm Paraxial Mesoderm • Paraxial mesoderm organized into segments – SOMITOMERES • Occurs in craniocaudal sequence and start from occipital region • 1st developed by day 20 (3 pairs per day) – 5th week • Gives axial skeleton Intermediate Mesoderm • Differentiate into Urogenital structures • Pronephros, mesonephros Lateral Plate Mesoderm • Parietal mesoderm + ectoderm = lateral body wall folds • Dermis of skin • Bones + CT of limb + sternum • Visceral Mesoderm + endoderm = wall of gut tube • Parietal mesoderm surrounding cavity = pleura, peritoneal and pericardial cavity • Blood &
    [Show full text]
  • Adnexal Masses in Pregnancy
    A guide to management Mitchel S. Hoffman, MD Professor and Director, Division of Adnexal masses in pregnancy Gynecologic Oncology, Department of Obstetrics and Gynecology, Forego surgery in most cases until delivery—or until University of South Florida, Tampa, Fla Robyn A. Sayer, MD the risky fi rst trimester has passed Assistant Professor, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, CASE 1 An enlarging cystic tumor 16 × 12 × 4 cm and determined that it University of South Florida, Tampa, Fla was a corpus luteum cyst. The authors report no fi nancial relationships relevant to this article. A 20-year-old gravida 3 para 1011 visits the emergency department with persistent right Presence of mass raises questions fl ank pain. Although ultrasonography (US) Despite the rarity of malignancy, the dis- shows a 21-week gestation, the patient has covery of an ovarian mass during pregnan- had no prenatal care. Imaging also reveals a® Dowdency prompts several Health important Media questions: right-sided ovarian tumor, 14 × 11 × 8 cm, How should the mass be assessed? How that is mainly cystic with some internal can the likelihood of malignancy be deter- echogenicity. CopyrightFor personalmined as quickly use and only effi ciently as pos- At 30 weeks’ gestation, a gynecologic sible, without jeopardy to the pregnancy? oncologist is consulted. Repeat US reveals When is surgical intervention warranted? the mass to be about 20 cm in diameter and And when can it be postponed? Specifi - cystic, without internal papillation. The pa- cally, is elective operative intervention for IN THIS ARTICLE tient’s CA-125 level is 12 U/mL.
    [Show full text]
  • Female Adnexal Tumor of Probable Wolffian Origin, FATWO: Report of a Rare Case
    J Cases Obstet Gynecol, 2016;3(1):15-18 Jo ur nal o f Ca se s in Ob st et ri cs &G ynec olog y Case Report Female adnexal tumor of probable wolffian origin, FATWO: Report of a rare case Cevdet Adiguzel1,*, Eylem Pinar Eser2, Sebnem Baysal1, Esra Selver Saygili Yilmaz1, Eralp Baser1 1 Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, Adana, Turkey 2 Department of Pathology, Adana Numune Education and Research Hospital, Adana, Turkey Abstract Female adnexal tumors of probable Wolffian origin (FATWO) arise in the broad ligament from the remnants of the me- sonephric duct. The behavior of these tumors is generally benign. However, they can also behave aggressive- ly and exhibit recurrences or metastases. Herein we present a rare case of FATWO that was diagnosed in a premenopausal woman. Key words: Adnexal mass, FATWO, wolffian Introduction Case presentation Female adnexal tumors of probable Wolffian origin (FAT- A 42-year-old pre-menopausal woman, gravida 2, para 2, WO) were first documented in 1973 by Kariminejad and was referred to our clinic for evaluation of a left adnexal Scully [1]. These tumors arise in the broad ligament from mass suspected to be malignant. Her previous gynecolog- the remnants of the mesonephric duct such as epoophoron, ical history included a cesarean section for dystocia. Pel- paroophoron and Gartner’s duct [2]. Approximately 80 cas- vic ultrasound showed a normal sized uterus, with a thin es of FATWO have been previously reported in the litera- and regular endometrial lining. The right ovary was nor- ture [3].
    [Show full text]
  • Rotana Alsaggaf, MS
    Neoplasms and Factors Associated with Their Development in Patients Diagnosed with Myotonic Dystrophy Type I Item Type dissertation Authors Alsaggaf, Rotana Publication Date 2018 Abstract Background. Recent epidemiological studies have provided evidence that myotonic dystrophy type I (DM1) patients are at excess risk of cancer, but inconsistencies in reported cancer sites exist. The risk of benign tumors and contributing factors to tu... Keywords Cancer; Tumors; Cataract; Comorbidity; Diabetes Mellitus; Myotonic Dystrophy; Neoplasms; Thyroid Diseases Download date 07/10/2021 07:06:48 Link to Item http://hdl.handle.net/10713/7926 Rotana Alsaggaf, M.S. Pre-doctoral Fellow - Clinical Genetics Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, NIH PhD Candidate – Department of Epidemiology & Public Health, University of Maryland, Baltimore Contact Information Business Address 9609 Medical Center Drive, 6E530 Rockville, MD 20850 Business Phone 240-276-6402 Emails [email protected] [email protected] Education University of Maryland – Baltimore, Baltimore, MD Ongoing Ph.D. Epidemiology Expected graduation: May 2018 2015 M.S. Epidemiology & Preventive Medicine Concentration: Human Genetics 2014 GradCert. Research Ethics Colorado State University, Fort Collins, CO 2009 B.S. Biological Science Minor: Biomedical Sciences 2009 Cert. Biomedical Engineering Interdisciplinary studies program Professional Experience Research Experience 2016 – present Pre-doctoral Fellow National Cancer Institute, National Institutes
    [Show full text]
  • A Contribution to the Morphology of the Human Urino-Genital Tract
    APPENDIX. A CONTRIBUTION TO THE MORPHOLOGY OF THE HUMAN URINOGENITAL TRACT. By D. Berry Hart, M.D., F.R.C.P. Edin., etc., Lecturer on Midwifery and Diseases of Women, School of the Royal Colleges, Edinburgh, etc. Ilead before the Society on various occasions. In two previous communications I discussed the questions of the origin of the hymen and vagina. I there attempted to show that the lower ends of the Wolffian ducts enter into the formation of the former, and that the latter was Miillerian in origin only in its upper two-thirds, the lower third being formed by blended urinogenital sinus and Wolffian ducts. In following this line of inquiry more deeply, it resolved itself into a much wider question?viz., the morphology of the human urinogenital tract, and this has occupied much of my spare time for the last five years. It soon became evident that what one required to investigate was really the early history and ultimate fate of the Wolffian body and its duct, as well as that of the Miillerian duct, and this led one back to the fundamental facts of de- velopment in relation to bladder and bowel. The result of this investigation will therefore be considered under the following heads:? I. The Development of the Urinogenital Organs, Eectum, and External Genitals in the Human Fcetus up to the end of the First Month. The Development of the Permanent Kidney is not CONSIDERED. 260 MORPHOLOGY OF THE HUMAN URINOGENITAL TRACT, II. The Condition of these Organs at the 6th to 7th Week. III.
    [Show full text]
  • PATHOLOGY of FEMALE GENITALE SYSTEM What Is the Benefit of Knowing This System?
    PATHOLOGY OF FEMALE GENITALE SYSTEM What is the benefit of knowing this system? It is certain that the detailed examination of these diseases and their knowledge will play an important role in the development of healthy animal populations. This success will also affect the economy. OVARIUM Developmental anomalies Agenesis of one or both ovaries is rare, but is observed in ruminants, swine, and dogs. In bilateral agenesis, the tubular genitalia may be absent as part of the defect or, if present, are infantile or underdeveloped. Ovarian remnants. Interest in the occurrence of anomalous ovarian duplication commonly arises when either cats or dogs, supposedly surgically neutered, exhibit signs of estrus. In the bitch, the effects of circulating estrogen are easily detected by serial vaginal cytology. Hormonal studies are confirmatory, and ultrasonographic and exploratory surgical examinations are also done. Duplication of ovarian tissues is very rare. Although there are no controlled studies, duplication may just be splitting of ovarian tissue. Hypoplasia of the ovaries is studied primarily in cattle, but occurs in other species. It is usually bilateral but varies considerably in its severity and symmetry so that “severe hypoplasia” or “partial hypoplasia” may be applicable to one or both ovaries. In severe hypoplasia, the defective gonad varies in size from a cordlike thickening in the cranial border of the mesovarium to a flat, smooth, firm, bean-shaped structure in the normal position. There are neither follicles nor luteal scars and, microscopically, the ovary is largely composed of medullary connective tissues and blood vessels. Ectopic adrenal tissue is usually found incidentally during histopathology.
    [Show full text]