US 20140356295A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2014/0356295 A1 Gerardi et al. (43) Pub. Date: Dec. 4, 2014

(54) COSMETIC COMPOSITIONS COMPRISING A61O 19/02 (2006.01) TOBACCO SEED-DERVED COMPONENT A61O 19/04 (2006.01) A61O5/00 (2006.01) (71) Applicant: R.J. REYNOLDS TOBACCO A61O 19/08 (2006.01) COMPANY, Winston-Salem, NC (US) A61O 19/10 (2006.01) A61O 19/00 (2006.01) (72) Inventors: Anthony Richard Gerardi, (52) U.S. Cl. Winston-Salem, NC (US); Barry Smith CPC ...... A61K 8/97 (2013.01); A61O 19/007 Fagg, Winston-Salem, NC (US); (2013.01); A61O 9/02 (2013.01); A61O 5/02 Thaddeus Jude Jackson, High Point, (2013.01); A61O 5/12 (2013.01); A61O5/06 NC (US) (2013.01); A61O5/04 (2013.01); A61O5/065 (2013.01); A61O 5/08 (2013.01); A61O 1/02 (21) Appl. No.: 13/908,684 (2013.01); A61O 700 (2013.01); A61O 1704 1-1. (2013.01); A61O 19/02 (2013.01); A61O 19/04 (22) Filed: Jun. 3, 2013 (2013.01); A61O5/006 (2013.01); A61O 19/08 Publication Classification (2013.01); A61O 19/10 (2013.01); tige (51) Int. Cl. USPC 424/43; 424/751; 424/73; 42.93. A 6LX8/97 (2006.01) s A61O 9/02 (2006.01) A61O 5/02 (2006.01) (57) ABSTRACT A61O5/12 (2006.01) Cosmetic compositions are provided that include an extract A61O5/06 (2006.01) from a seed of the Nicotiana species, one or more cosmeti A61O5/04 (2006.01) cally acceptable carriers to act as a diluent, dispersant or A61O5/08 (2006.01) carrier for the composition, and optionally one or more cos A61O I/02 (2006.01) metic adjuvants. The tobacco seed extract is typically char A61O 700 (2006.01) acterized as having a significant lipid content and, thus, finds A61O 1704 (2006.01) use as an oil component in a cosmetic composition. US 2014/0356295 A1 Dec. 4, 2014

COSMETC COMPOSITIONS COMPRISING 0006 Various oils can be used in the oily phase of cos TOBACCO SEED-DERVED COMPONENT metic compositions in the form of emulsions. Natural oils can be vegetable oils that consist of aethereal salts of glycerin FIELD OF THE INVENTION with a large number of organic acids Such as Stearic acid, oleic acid, and palmitic acid, forming Stearin, olein, and palmitin, 0001. The present invention relates to cosmetic products respectively. Stearin and palmitin are common Solid oils and comprising a components made or derived from tobacco. Of used in cosmetic compositions. Olein is a common liquid particular interest are oil compositions obtained or derived oil used in cosmetic compositions. Natural oils can function, from plant seeds orportions of plant seeds from the Nicotiana for example, as excellent emollients that leave the hair and species. skin Soft and Smooth. Oils can also penetrate the skin and provide effective nourishing and revitalizing effects. There BACKGROUND OF THE INVENTION fore, natural oils are used in a wide variety of cosmetic prod ucts, including personal care as well as makeup products. 0002 Cosmetics are generally defined as substances used 0007. A growing number of cosmetic products are to enhance the appearance or odor of the human body. They directed towards rejuvenating the skin and removing unde are generally mixtures of chemical compounds, Some being sirable signs of aging such as wrinkles. Conventional prod derived from natural Sources and others being synthetic. In ucts often contain exfoliating acids as active ingredients. the U.S., the Food and Drug Administration (FDA), which Such anti-aging active ingredients include, for example, a-hy regulates cosmetics, defines cosmetics as “intended to be droxy acids (e.g., lactic, glycolic, citric), b-hydroxy acids applied to the human body for cleansing, beautifying, pro (e.g., Salicylic, 5-n-octanoylsalicylic acids) and retinoids (ret moting attractiveness, or altering the appearance without inoic acids; retinol). However, these anti-aging acids can be affecting the body's structure or functions.” associated with consumer discomfort characterized by burn 0003. There are many different types of cosmetic prod ing, stinging, itching or a sensation of tightness after appli ucts, including, but not limited to, hair treatment products cation. Such as shampoos and conditioners, body and facial cleans 0008. There is a continuing need for new cosmetic com ers, skin moisturizing products such as body creams and body positions that exhibit advantageous properties. Additionally, lotions, facial products such as eye creams, wrinkle reducing there remains a general need in the cosmetics industry for treatments and anti-aging products, make-up products, as products that retard or counter aging effects on the skin with well as various other products known in the field. Examples of out producing undesirable side effects. hair treatment compositions include U.S. Pat. No. 6,139.851 to Omura et al.; U.S. Appl. Pub. Nos. 2013/0090279 to Hilvert SUMMARY OF THE INVENTION et al. and 2012/0276210 to Dihora et al.; and EP 1778181 to 0009. The present invention provides an oil component Soulimani, each herein incorporated by reference in its made or derived from seeds from plants of the Nicotiana entirety. Examples of skin care products include U.S. Pat. No. species useful for incorporation into a variety of cosmetic 6,126,950 to Bindra et al., U.S. Pat. No. 6,544,530 to Fried products. Specifically, a cosmetic composition comprising an man et al., U.S. Pat. No. 6,368,639 to Farooqi, U.S. Pat. No. extract of a seed of the Nicotiana species and at least one 7,105,173 to Rolling, U.S. Pat. No. 8,372,825 to Turkowitz: cosmetically acceptable carrier, wherein the cosmetic com U.S. Appl. Pub. No. 2012/0238743 to Kim et al.; EP 1441686 position is in a form adapted for application to skin or hair is to Dokka et al.; and WO 2010/086724 to Surianarayanan et disclosed. In some embodiments, the extract is a tobacco seed al., WO 2011/147696 to Chodorowski-Kimmes et al., WO oil. In various embodiments, the tobacco seed oil has a free 2003/041636 to Dokka et al., each herein incorporated by content of less than about 15 weight percent, or less reference in its entirety. than about 10 weight percent, based on the total weight of the 0004 Many cosmetic compositions, such as cleansers and tobacco seed oil. In various embodiments of the present shampoo, contain detergents. Sodium lauryl Sulfate, ammo invention, the tobacco seed oil comprises at least about 60 nium lauryl Sulfate, Sodium laureth Sulfate, ammonium lau weight percent of linoleic acid, based on the total weight of reth Sulfate, Stearic acid, lauric acid, myristic acid, oleic acid the tobacco seed oil. and palmitic acid are a few of the common detergents or soaps 0010. In some embodiments, the cosmetic composition is found in cleansers. See, e.g., Antczak, Stephen, and Gina in the falai of an emulsion with an aqueous phase and an oily Antczak. Cosmetics Unmasked: Your Family Guide to Safe phase comprising tobacco seed oil derived from seeds from Cosmetics and Toiletries. London: Thorsons, 2001, herein plants of the Nicotiana species. In various embodiments, the incorporated by reference. Soaps can be made from vegetable composition is in the form of an emulsion, and comprises a oil or animal fats. Coconut oil, , safflower oil, jojoba cosmetically acceptable carrier that is an aqueous carrier. In oil and tallow, for example, are ingredients used in creating Some embodiments of the present invention, the cosmetic soap-based cleansers. These ingredients are mixed with an composition is in the form of a liquid, a lotion, a gel, a cream, alkaline Substance, usually sodium hydroxide, or lye, to cre a milk, an ointment, a paste, a plaster, a powder, a foam, a ate a salt. When mixed, in a process called Saponification, two make-up, a stick, an aerosol, or embedded or absorbed in a byproducts are generally created: glycerin and salt. wipe. 0005 Emulsions are among the most common types of 0011. In various embodiments, the cosmetic composition delivery systems used in cosmetic formulations. An emulsion is adapted for use as a body moisturizing oil, a body moistur is a dispersion of one liquid in a second, immiscible liquid. izing lotion, a body moisturizing gel, a body moisturizing Typically, cosmetic emulsions include an oily phase compris cream, a shaving preparation, a skin powder, a Suntan lotion, ing one or more hydrophobic, long-chain, organic molecules an anti-acne preparation, a peeling preparation, a shampoo, a and an aqueous phase. One or more emulsifiers are typically hair conditioners, a hair tonic, a hair styling cream, a hair present to maintain the emulsion in stable form over time. styling gel, a pomade, a hair rinse, a hair-straightening prepa US 2014/0356295 A1 Dec. 4, 2014

ration, a hair-setting preparation, a hairspray, a hair dying or 15% by weight, and one or more humectants in an amount up bleaching preparation, or a makeup. to about 10% by weight. In another embodiment, the cos 0012. In some embodiments of the present invention, the metic composition is in the form of an emulsion adapted for cosmetic composition further comprises one or more cos cleansing skin or hair (e.g., a facial cleanser or shampoo), metic adjuvants selected from the group consisting of addi wherein the cosmetic composition comprises water in an tional fats or lipids, organic solvents, thickeners, binders, amount up to about 80% by weight, a tobacco seed oil in an conditioning agents, demulcents, opacifiers, stabilizers, buff amount up to about 10% by weight, one or more emulsifiers ering agents, humectants, pigments, dyes, viscosity modifi in an amount up to about 15% by weight, and one or more ers, emollients, antiperspirants, anti-foaming agents, foam surfactants in an amount up to about 50% by weight. Either boosters, hair colorants, hair perming agents, hair growth or composition can include one more additional cosmetic adju restorer agents, hair loss prevention agents, abrasives, absor vants, such as any of the adjuvants noted herein in any repre bents, anti-acne agents, anti-caking agents, moisturizing sentative amount noted herein. agents, perfumes or fragrances (e.g., bergamot extract), pre servatives, Sunscreens, astringents, propellants, bleaching or DETAILED DESCRIPTION lightening agents for skin or hair, tanning agents, deposition 0016. The present invention now will be described more aids, Suspending agents, polymers, fillers, sequestrants, bac fully hereinafter. This invention may, however, be embodied tericides, odor absorbers, antifungal agents, alkalinizing or in many different forms and should not be construed as lim acidifying agents, pearlescent aids, chelants, proteins, anti ited to the embodiments set forth herein; rather, these embodi dandruff agents, Surfactants, emulsifiers, anti-free radical ments are provided so that this disclosure will be thorough agents, antioxidants, vitamins, and C-hydroxy acids. and complete, and will fully convey the scope of the invention 0013. In various embodiments, a cosmetic composition to those skilled in the art. As used in this specification and the comprising an extract of a seed of the Nicotiana species and claims, the singular forms “a,” “an,” and “the include plural at least one cosmetically acceptable carrier is provided, referents unless the context clearly dictates otherwise. Refer wherein the cosmetic composition is in a form adapted for ence to “dry weight percent’ or “dry weight basis” refers to application to skin or hair. The cosmetically acceptable car weight on the basis of dry ingredients (i.e., all ingredients rier can comprise water and the cosmetic composition can be except water). in the form of a lotion or cream emulsion with an aqueous 0017. In the present invention, cosmetic compositions are phase and an oily phase comprising a tobacco seed oil. In provided that include a tobacco derived component from any addition, the cosmetic composition can further comprise one portion of a Nicotiana plant species. In certain embodiments, or more cosmetic adjuvants selected from the group consist cosmetic compositions are provided that include an extract ing of additional oils, thickeners, Surfactants, preservatives, from a seed of the Nicotiana species and one or more cos pigments, humectants, emollients, occlusives, and combina metically acceptable carriers to act as a diluent, dispersant or tions thereof. carrier for the composition, so as to facilitate its distribution 0014. In certain embodiments, the cosmetic composition when the composition is applied to the skin or hair. Exem further comprises one or more emollients in an amount of plary carriers include water, and may include, in addition to or about 0.01 to about 20% by weight of the cosmetic compo in lieu of water, liquid or Solid emollients, organic or aqueous sition. The cosmetic composition can comprise, singly or as co-solvents, humectants, thickeners and powders. Aqueous mixtures of two or more components, one or more humec carriers include water or a miscible mixture of water and an tants in an amount of about 0.01 to about 10% by weight of the organic co-solvent (e.g., lower alkyl alcohols or polyhydric cosmetic composition, one or more Surfactants in an amount alcohols). The lower alkyl alcohols useful herein can com of about 0.01 to about 50% by weight of the cosmetic com prise monohydric alcohols having 1 to 6 carbons. In some position, one or more conditioning agents in an amount of embodiments, the solvent comprises ethanol, isopropanol, or about 0.01 to about 5% by weight of the cosmetic composi a mixture thereof. Polyhydric alcohols useful in cosmetic tion, one or more preservatives in an amount of about 0.01 to compositions can include, for example, propylene glycol about 10% by weight of the cosmetic composition, one or (PPG-12), hexylene glycol, glycerin, propane diol, and mix more thickening agents in an amount of about 0.01 to about tures thereof. In some embodiments, the solvent comprises 15% by weight of the cosmetic composition, one or more C13-14 isoparaffin. emulsifiers in an amount of about 0.01 to about 15% by 0018. The tobacco seed extract may comprise any weight of the cosmetic composition, one or more antioxidants extracted portion of a seed of the Nicotiana species (also in an amount of about 0.01 to about 10% by weight of the referred to generically hereinas a tobacco seed extract). Typi cosmetic composition, one or more natural or essential oils in cally, such extracts are characterized as having a significant an amount of about 0.01 to about 20% by weight of the lipid content and, thus, find use as an oil component in a cosmetic composition, one or more occlusives in an amount cosmetic composition. Examples of the types of components of about 0.01 to about 5% by weight of the cosmetic compo that can be present in a tobacco seed extract include various sition, and/or one or more agents useful for treating wrinkles fatty acids and . Exemplary fatty acids include in the skin in an amount of about 0.01 to about 5% by weight palmitic acid, linoleic acid, oleic acid, caprylic acid, myristic of the cosmetic composition. acid, pentadecanoic acid, palmetoleic acid, heptadecanoic 0015. In one embodiment, the cosmetic composition is in acid, heptadecenoic acid, elaidic acid, gamma-lenolenic acid, the form of an emulsion adapted for moisturizing skin (e.g., a arachidic acid, arachidonic acid, 11-eicosenoic acid, 8,11,14 lotion, cream, or body butter), wherein the cosmetic compo eicosatrieonic acid, 11.14.17-eicosatrienoic acid, 5,8,11,14. sition comprises water in an amount up to about 80% by 17-eicosopentanoic acid, heniecoSenoic acid, lignoceric acid, weight, a tobacco seed oil in an amount up to about 10% by 4,7,10,15,19-decosahexanoic acid, and stearic acid. Exem weight, one or more emollients in an amount up to about 20% plary triglycerides include trilinolein, palmito-di-linolein, di by weight, one or more emulsifiers in an amount up to about palmito-linolein, tripalmitin, tristearin, and triolein. US 2014/0356295 A1 Dec. 4, 2014

0019. In certain embodiments, the fatty acid content (in provide beneficial effects on skin and hair, particularly when cluding free and -bound fatty acids) of the dealing with problems such as acne, dryness, and Swelling. In tobacco seed extracts of the invention comprises greater than certain embodiments, cosmetic products incorporating about 50% by weightlinoleic acid, such as greater than about tobacco seed oil can also be effective in cell regulation and 60% by weight or greater than about 65% by weight. In skin-barrier repair, as well as provide an antioxidant and an certain embodiments, the total linoleic acid content is about anti-inflammatory effect. Furthermore, tobacco seed oil can 65% to about 80% by weight of the fatty acids in the tobacco be used as an effective and efficient emollient in cosmetic seed extract. Tobacco seed extracts containing a majority compositions. In some compositions, tobacco seed oil can amount of lipids (e.g., greater than about 50% by weight) is also function as a surfactant in a cosmetic composition. referred to herein as tobacco seed oil. Exemplary components 0025 Cosmetic compositions of the invention can be in of tobacco seed extracts also include a variety of other com the form of a liquid, a lotion, a thickened lotion, agel, a cream, pounds having flavorand aroma characteristics such as amino a milk, an ointment, a paste, a plaster, a powder, a foam, a acids and various polyphenols. make-up, or a stick, and can optionally be packaged as an 0020. In many cosmetic products, oil components forman aerosol Such as an aerosol mousse or spray foam, or embed important part of the formulation. Oil components can be ded or absorbed in a wipe. In some embodiments, the com categorized into three major groups including oils (including positions according to the invention are provided in the form fats/butters), esters, and waxes. All of these groups can func of a simple or complex emulsion (e.g., O/W, W/O, O/W/O or tion as emollients, but based on their different chemical struc W/O/W), and more particularly in the form of a lotion or tures they can also have different additional properties. CCa: 0021 Oils and fats differ in that fats are generally solid at 0026. The tobacco seed extract of the invention can find room temperature. Both fats and oils are comprised of trig use in a variety of cosmetic formulations, including skin care lycerides, which are glycerol esters having a glycerol core preparations (e.g., body oils, body lotions, body gels, treat with attached fatty acids. Fatty acids can be saturated or ment creams, skin protection ointments, shaving preparations unsaturated, which can determine the stability and property of Such as shaving foams or gels, skin powders such as baby the oil. Saturated oils are more stable and do not become powder, moisturizing gels, moisturizing sprays, revitalizing rancid as quickly as unsaturated oils. However, unsaturated body sprays, cellulite gels, Suntan lotions and oils, anti-acne oils are Smoother, less greasy, and in Some embodiments, can preparations, and peeling preparations); hair care prepara be absorbed better by the skin. tions (e.g., shampoos, hair conditioners, hair tonics, styling 0022. Linoleic acid is an important fatty acid that the body creams, styling gels, pomades, hair rinses, hair-straightening needs in order to Survive. Its benefits are many, encompassing preparations, hair-setting preparations, hair foams, hair systemic health benefits as well as cosmetic benefits to the sprays, lacquers, perming agents, and hair dying or bleaching skin and hair. Linoleic acid can be derived from animal fats, agents); decorative or makeup preparations (e.g., lipstick, eye and also found in vegetable-derived oils, Soy lecithin, saf shadow, mascaras, dry and moist make-up, rouge, and pow flower oil, bitter oil, and , for example. ders); as well as various pharmaceutical formulations applied 0023 Linoleic acid is an unsaturated fatty acid that can be to skin or hair such as hormone compositions, vitamin com used, for example, as an emollient and thickening agent in positions, and antimicrobial (e.g., antibacterial or antifungal) cosmetic compositions. Many of its properties can help skin compositions. with problems such as acne, dryness, and Swelling. There is 0027. The compositions of the invention may additionally Some research showing it to be effective in cell regulation and comprise one or more conventional cosmetic adjuvants, such skin-barrier repair, as well as an antioxidant and an anti as additional or lipid substances, organic solvents, thick inflammatory. Archives of Dermatological Research, July eners, binders, conditioning agents (e.g., hydrocarbon oils, 1998, pages 375-381; Clinical and Experimental Dermatol fatty esters, silicones), demulcents, opacifiers, stabilizers, ogy, March 1998, pages 56-58, Journal of Investigative Der buffering agents, humectants, pigments, dyes, viscosity matology, May 1996, pages 1096-1101; and Seminars in modifiers, emollients, antiperspirants, anti-foaming agents, Dermatology, June 1992, pages 169-175. In certain embodi foam boosters, hair colorants, hair perming agents, hair ments, linoleic acid can enable the skin to hold moisture growth or restorer agents, hair loss prevention agents, abra better Such that both a Soothing and moisturizing effect is sives, absorbents, anti-acne agents, anti-caking agents, mois associated with compositions including linoleic acid. For at turizing agents, perfumes or fragrances, preservatives, Sun least these reasons, linoleic acid can be beneficial for many screens, astringents, propellants, bleaching or lightening cosmetic products Such as lotions, creams, soaps, and even agents for skin or hair, tanning agents, deposition aids, Sus Some medications. Accordingly, the high content of linoleic pending agents, polymers, fillers, sequestrants, bactericides acid found in tobacco seed extracts renders such extracts and/or odor absorbers, antifungal agents, alkalinizing or particularly beneficial in cosmetic formulations. acidifying agents, pearlescent aids, chelants, proteins, anti 0024. Addition of the tobacco seed extract of the invention dandruff agents, Surfactants, emulsifiers, anti-free radical to a cosmetic composition can enhance a cosmetic composi agents, antioxidants, vitamins (e.g., vitamins A, B1, B2, B6. tion in a variety of ways, depending on the nature of the seed B12, C, D, E, etc. and their derivatives), C-hydroxy acids, or extract and the type of cosmetic composition. Exemplary any other ingredient normally used in cosmetics. Commonly seed extracts can serve to provide flavor and/or aroma to a used natural and synthetic adjuvants are described, for cosmetic product (e.g., composition that alters the sensory example, in Breslawec, Halyna P., and Tara E. Gottschalck. characteristics of cosmetic compositions). A tobacco seed International Cosmetic Ingredient Dictionary and Hand extract can also provide an advantageous source of linoleic book. Washington, D.C.: Personal Care Products Council, acid in cosmetic products. Tobacco seed oil can replace the oil 2012. (hereinafter “Cosmetic Handbook”) and Personal Care components conventionally used in cosmetic products. The Products Council (formerly the Cosmetic, Toiletry and Fra high concentration of linoleic acid of the tobacco seed oil can grance Association or CTFA) ingredient information (see US 2014/0356295 A1 Dec. 4, 2014 http://www.personalcarecouncilorg/public-information/con incorporate relatively high levels of specific desired compo Sumer-ingredient-information), the content of which is nents, and the like. Additional information on types of Nic hereby incorporated by reference in its entirety. Otiana species Suitable for use in the present invention can be 0028. The amount of tobacco seed extract will vary found in US Pat. Appl. Pub. No. 2012/0192880 to Dube et al., depending on the type of cosmetic composition and its which is incorporated by reference herein. Tobacco plants can desired function within the formulation. Typically, tobacco be grown in greenhouses, growth chambers, or outdoors in seed extracts can be used in the same amounts conventionally fields, or grown hydroponically. used for lipid components in cosmetic formulations. In cer 0033. The manner by which the seed is harvested can vary. tain embodiments, the tobacco seed extract is present in an Typically, the seed is removed from the rest of the plant by amount of about 0.1% by weight to about 20% by weight, cutting or breaking the so-called seed head or seed capsule such as about 1% to about 10% by weight, based on the total from the rest of the plant. Virtually all of the seed (e.g., the weight of the cosmetic formulation. In some embodiments, whole seed) can be harvested and employed as such. Seeds the amount of tobacco seed extract can be characterized as at can be isolated using typical mechanical separation and col least about 0.5% by weight, at least about 1.0% by weight, at lection techniques. least about 1.5% by weight, or at least about 2.0% by weight, 0034. The time of harvest during the life cycle of the plant based on total weight of the cosmetic formulation. can vary. For example, the seed can be harvested when imma 0029. The cosmetically acceptable carrier will usually ture, and as Such, the inflorescence or flower head can be form from about 5% to about 99.9%, preferably from about removed from the plant. Alternatively, the seed head or seed 25% to about 80% by weight of the cosmetic formulation. capsule can be harvested from the plant after the point that the Typically, the carrier is at least 80% by weight water, based on seed has reached maturity. total weight of the carrier. In certain embodiments, water 0035. The post-harvest processing of the seed can vary. comprises at least 50% by weight of the inventive composi After harvest, the seed, or portion thereof, can be used in the tion, most often from about 60 to about 80% by total weight harvested form (e.g., the seed can be used without being of the composition. Subjected to any curing and/or aging process steps). For 0030 The total amount of various adjuvants contained in example, the seed can be used without being Subjected to the cosmetic formulations of the invention can vary, depend significant storage, handling or processing conditions. In cer ing on the cosmetic type and desired functionality of the tain situations, it is preferable that the fresh seed be used formulation. In some embodiments, each cosmetic adjuvant virtually immediately after harvest. Alternatively, the tobacco will be present in an amount of about 0.1% by weight to about seed material can be subjected to various treatment processes 20% by weight (e.g., about 0.5% to about 10% by weight) and Such as, refrigeration, freezing, drying (e.g., freeze-drying or the total adjuvant content will be about 15% to about 40% by spray-drying), irradiation, yellowing, heating, cooking (e.g., weight (e.g., about 20% to about 30% by weight), based on roasting, frying or boiling), fermentation, bleaching or other the total weight of the formulation. wise Subjected to storage or treatment for later use. Exem plary processing techniques are described, for example, in US Method of Forming Tobacco Seed Extract Pat. Appl. Pub. Nos. 2009/0025739 to Brinkley et al. and 0031. The seed material used in the invention is provided 2011/0174323 to Coleman, III et al., which are incorporated from the seed of the plant of the Nicotiana species, which is by reference herein. the characteristic reproductive structure of the plant (e.g., 0036. At least a portion of the seed of the Nicotiana spe seed producing structure). See, for example, Frega et al., cies can be treated with enzymes and/or probiotics before or JAOCS, 68, 29-33 (1991); Patel et al., Tob. Res., 24, 44-49 after harvest, as discussed in U.S. patent application Ser. No. (1998); Giannelos et al., Ind. Crops Prod., 16, 1-9 (2002); 13/444,272 to Marshallet al., filed on Apr. 11, 2012 and U.S. Mukhtar et al., Chinese J. Chem., 25, 705-708 (2007): patent application Ser. No. 13/553,222 to Moldoveanu, filed Stanisavljevic et al., Eur: J. Lipid Sci. Technol., 111,513-518 on Jul.19, 2012, which are incorporated herein by reference. (2009); which are incorporated herein by reference. 0037. The harvested seed can be physically processed. 0032. The selection of the plant from the Nicotiana spe The seed, or parts thereof, can be further subdivided into parts cies can vary; and in particular, the types of tobacco or tobac or pieces (e.g., the seed can be comminuted, pulverized, cos may vary. Tobaccos that can be employed include flue milled or ground into pieces or parts that can be characterized cured or Virginia (e.g., K326), burley, Sun-cured (e.g., Indian as granules, particulates or fine powders). The seed, or parts Kurnool and Oriental tobaccos, including Katerini, Prelip, thereof, can be subjected to external forces or pressure (e.g., Komotini, Xanthi and Yambol tobaccos), Maryland, dark, by being pressed or subjected to roll treatment). When carry dark-fired, dark air cured (e.g., Passanda, Cubano, Jatin and ing out Such processing conditions, the seed can have a mois Bezuki tobaccos), light air cured (e.g., North Wisconsin and ture content that approximates its natural moisture content Galpao tobaccos), Indian air cured, Red Russian and Rustica (e.g., its moisture content immediately upon harvest), a mois tobaccos, as well as various other rare or specialty tobaccos. ture content achieved by adding moisture to the seed or a Descriptions of various types of tobaccos, growing practices moisture content that results from the drying of the seed. For and harvesting practices are set forth in Tobacco Production, example, powdered, pulverized, ground or milled pieces of Chemistry and Technology, Davis et al. (Eds.) (1999), which seed can have moisture contents of less than about 25 weight is incorporated herein by reference. Nicotiana species can be percent, often less than about 20 weight percent, and fre derived using genetic-modification or crossbreeding tech quently less than about 15 weight percent. Parts or pieces of niques (e.g., tobacco plants can be genetically engineered or the seed can be used as components of cosmetic products crossbred to increase or decrease production of or to other without further processing, or alternatively the particulate change certain components, characteristics or attributes). For seed material can be processed further prior to incorporation example, the Nicotiana species can be selected on the basis of into a cosmetic product. The harvested seed, or components producing relatively numerous seeds, or producing seeds that thereof, can be subjected to other types of processing condi US 2014/0356295 A1 Dec. 4, 2014 tions. For example, components of the seed can be separated aid can be employed to provide effective filtration and can from one another, or otherwise fractionated into chemical comprise any material typically used for this purpose. For classes or mixtures of individual compounds, as set forth example, Some common filter aids include cellulose fibers, more fully below, in order to form a tobacco seed extract. perlite, bentonite, diatomaceous earth, and other siliceous 0038. Typical separation processes can include one or materials. To remove Solid components, alternative methods more process steps such as solvent extraction (e.g., using can also be used, for example, centrifugation or settling/ polar solvents, non-polar organic solvents, or Supercritical sedimentation of the components and siphoning off of the fluids), chromatography, distillation, filtration, cold pressing liquid. or other pressure-based techniques, recrystallization, and/or 0043 Although in some embodiments, the tobacco extract Solvent-solvent partitioning. Exemplary extraction and sepa is used directly, it may be desirable to thermally treat the ration solvents or carriers include water, alcohols (e.g., tobacco extract in order to, for example, pasteurize the mate methanol or ethanol), hydrocarbons (e.g., heptane and hex rial or otherwise chemically alter the material. This thermal ane), diethyl ether methylene chloride and supercritical car treatment can be conducted before or after any of the pro bon dioxide. Exemplary techniques useful for extracting cesses described herein for the extraction of one or more components from Nicotiana species are described in or ref components from a plant of the Nicotiana species. For erenced in US Pat. Appl. Pub. Nos. 2011/0259353 to Cole example, a tobacco extract can be thermally processed by man, III et al. and 2012/0211016 to Byrd, Jr. et al., which are mixing the tobacco extract, water, and an additive such as an incorporated by reference herein. Various other additives can amino acid or asparaginase; and heating the moist tobacco be used in the extraction process, including, but not limited to, mixture at a temperature of at least about 60° C. to form a Surfactants and co-solvents. heat-treated tobacco mixture. Such heat treatment can help 0039. The conditions of the extraction process can vary. In prevent acrylamide production resulting from reaction of Some embodiments, the seed of the Nicotiana species is com asparagine with reducing Sugars in tobacco materials and can bined with a solvent to form a suspension or slurry. In certain provide Some degree of pasteurization. See, for example, US embodiments, the amount of Solvent added can be at least Pat. Pub. No. 2010/0300463 to Chen et al., which is incorpo about 50 weight percent, or at least about 60 weight percent, rated herein by reference. or at least about 70 weight percent, based on the total weight 0044 Additionally, the tobacco extract can be brought into of the Suspension or slurry. In some cases, the amount of contact with an imprinted polymer or non-imprinted polymer solvent can be described as at least about 80 weight percent or such as described, for example, in US Pat. Pub. Nos. 2007/ at least about 90 weight percent. 0186940 to Bhattacharyya etal; 2011/0041859 to Rees et al.: 0040. The temperature and pressure of the extraction pro and 2011/01591.60 to Jonsson et al; and U.S. patent applica cess can vary. Exemplary temperatures include room tem tion Ser. No. 13/111.330 to Byrdet al., filed May 19, 2011, all perature or an elevated temperature, such as greater than of which are incorporated herein by reference. Treatment about 50° C., greater than about 60°C., greater than about 70° with a molecularly imprinted or non-imprinted polymer can C., greater than about 80° C., or greater than about 90° C. be used to remove certain components of the extract, such as Typical pressures experienced during extraction range from Hoffmann analytes. about atmospheric pressure to about 1,000 psig. 0045 Various methods of solvent removal can be 0041. The amount of time required to effectuate extraction employed, such as heat treatment to evaporate the solvent, is partially dependent on the temperature and pressure at reverse osmosis membrane treatment, spray drying or freeze which the extraction is conducted. For example, in some drying. In one embodiment, the concentration process can embodiments, heating the material to an elevated temperature entail heating the extracted liquid in a vented vessel to evapo and/or pressurizing the material increases the rate of extrac rate a portion of the water. The temperature and pressure at tion. The time range for the extraction process is typically at which the liquid is heated may vary. See, for example, the least about 30 minutes (e.g., at least about 1 hour or at least solvent removal techniques set forth in US Pat. Pub. No. about 2 hours) and typically less than about 24 hours (e.g., 2012/0152265 to Dube et al., which is incorporated by refer less than about 12 hours or less than about 8 hours), although ence herein. other time periods could be used without departing from the 0046. Of particular interest in the present invention is the invention. In some embodiments, multiple extractions can be oil that can be extracted from the tobacco seeds. Methods of conducted to extract additional compounds therefrom. See, extracting oil components from plant seeds are described, for for example, US Patent App. Publ. No. 2008/0254149 to example, in U.S. Pat. No. 4,008,210 to Steele et al.; U.S. Pat. Havlin-Frenkel, which is incorporated herein by reference. No. 4,009,290 to Okumori et al.; U.S. Pat. No. 4,045,879 to 0042. In some embodiments, a tobacco extract described Witte; U.S. Pat. No. 4,122,104 to Witte: U.S. Pat. No. 4,298, herein is further treated by filtration. Extracts can, in some 540 to Younet al.; U.S. Pat. No. 4,359,417 to Karnofsky et al.: embodiments, comprise some level of solid (insoluble) mate U.S. Pat. No. 4,456.556 to Grimsby: U.S. Pat. No. 4,456,557 rial entrained in the liquid. Following extraction, an extracted to Grimsby: U.S. Pat. No. 4,466,923 to Friedrich; U.S. Pat. liquid component can thus be filtered to remove at least some No. 4,515,726 to Sullivan; U.S. Pat. No. 4,847,106 to Pike et of the solids. In other words, some or all of the portion of the al.; U.S. Pat. No. 5,077,071 to Strop; U.S. Pat. No. 5,296,621 plant material that is insoluble in the extraction solvent is to Roos et al.; U.S. Pat. No. 5,397.571 to Roland et al.; U.S. removed. The process of filtration can comprise passing the Pat. No. 5,932,095 to Walters et al.; U.S. Pat. No. 6,083,729 to liquid through one or more filter screens to remove selected Martin et al.; U.S. Pat. No. 6,225,483 to Franke; U.S. Pat. No. sizes of particulate matter. Screens may be, for example, 6,403,126 to Webster et al.; U.S. Pat. No. 6,414,172 to Garces stationary, vibrating, rotary, or any combination thereof. Fil et al.; U.S. Pat. No. 6,417,157 to Wadsworth et al.; U.S. Pat. ters may be, for example, press filters or pressure filters. In No. 6,495,175 to Rao et al.; U.S. Pat. No. 6,504,085 to some embodiments, the filtration method used can involve Howard; U.S. Pat. No. 6,860,998 to Wilde; U.S. Pat. No. microfiltration, ultrafiltration, and/or nanofiltration. A filter 7,074,449 to Holley et al.; and U.S. Pat. No. 7,156,981 to US 2014/0356295 A1 Dec. 4, 2014

Wilde et al.; US Patent Appl. Pub. Nos. 2002/0121628 to triglyceride bound fatty acids and only about 1-4% free fatty Kapila et al., 2004/0009242 to Krasutsky et al., 2005/ acids. Regardless of whether the fatty acids are free or bound, 0.042347 to Bathurst et al., 2005/0147722 to Fanet al., 2006/ the proportion of fatty acids in various embodiments of 01 11578 to Arhancet et al., and 2011/0259353 to Coleman III tobacco seed oil can be about 69-71% by weightlinoleic acid, et al.; and WO 2009/110775 to Murzagaliyev et al., all of about 11-13% oleic acid, about 8-11% palmitic, about 3-5% which are incorporated by reference herein. stearic acid, and about 2-3% various other medium chained 0047. There are a number of methods for extracting fatty acids. Tobacco seed oil can be characterized by analysis tobacco seed oil. The relevant part of the plant may be placed of free fatty acids by using trimethylsilylation (TMS) deriva underpressure to extract the oil, which provides an expressed tization followed by GC-MS analysis. For triglyceride bound oil. Oils may also be extracted from tobacco by dissolving fatty acids, the fatty acids are base hydrolyzed from glycerin tobacco seeds in a suitable solvent. The Solution is then sepa and then analyzed by the same method. Fatty acid content can rated from the plant material and concentrated, giving an also be measured by using standardized methods provided by extracted or leached oil. Alternatively, the oil can be extracted the Association of Analytical Communities (AOAC) or the by distilling the oil away from the plant material, thereby American Oil Chemists Society (AOCS). giving an . A fourth method includes infusing 0.052 A tobacco seed oil of the invention can be further parts of plants in a base oil, a process called liquid-liquid refined in order to reduce the free fatty acid content thereof in extraction, and thereby making a . order to enhance storage stability. For example, in certain 0048 Components of the tobacco seed can be subjected to embodiments, a crude tobacco seed oil will have about 20% to conditions so as to cause those components (whether as part about 30% by weight free fatty acid content. Both physical of the seed or in the form of a seed extract) to undergo and chemical refining techniques (or combinations thereof) chemical transformation. For example, seed extracts that can be used. Physical techniques include distillation, which have been separated from the seed can be treated to cause separates the free fatty acids from the desired triglycerides chemical transformation. The chemical transformations or based on difference in boiling point. A typical chemical refin modification of the seed extract can result in changes of ing technique involves alkaline neutralization of the fatty certain chemical and physical properties of those seed acids, dilution of the resulting aqueous-soluble phase, and extracts (e.g., the sensory attributes of those extracts). Exem separation of the neutralized acids from the remaining lipid plary chemical modification processes can be carried out by components, such as by centrifugation. In certain embodi acid/base reaction, hydrolysis, heating (e.g., a thermal treat ments, the refined tobacco seed oil of the invention has a free ment where the seed isolate is subjected to an elevated tem fatty acid content of less than about 15% by weight, such as perature such as a temperature of at least about 50° C. or at less than about 10% by weight, less than about 8% by weight, least about 75° C. or at least about 90° C.), and enzymatic or less than about 5% by weight, based on the total weight of treatments (e.g., using hydrolyase, glycosidase, or glucoci the tobacco seed oil. dase); and as Such, components of the seed extract can 0053. The form of the tobacco seed extract can vary. Typi undergo esterification, transesterification, isomeric conver cally, the seed extract is in a solid, liquid, or semi-solid or gel Sion, acetal formation, acetal decomposition, and the like. form. The seed extract can be used in concrete, absolute, or Additionally, various isolated lipid components of the seed neat form. The seed extract can have a dry particulate form, a extract can be subjected to hydrogenation in order to alter the waxy form, or a thick paste form. The tobacco extract can also degree of saturation of those components, and hence alter the be used in an encapsulated form, Such as encapsulated within physical form or behavior of those components. microcapsules having an outer wall and an inner payload that 0049. In one aspect, tobacco seed can be cold pressed in includes the extract. order to Squeeze lipids from the seed, and those lipid compo 0054 Although particularly advantageous embodiments nents are collected and optionally further isolated; or alterna of the invention focus on extracts from tobacco seeds, such as tively the seed can be subjected to solvent extraction using a tobacco seed oil, other components of the tobacco plant or Solvent (e.g., a polar solvent or a non-polar organic solvent), extracts thereof could also be used in a cosmetic formulation. and the resulting extract is collected and the extracted com For example, components of a tobacco plant. Such as leaves, ponents are optionally further isolated. Still further, tobacco stem, stalk, roots, lamina, flowers, and various portions and seed material is optionally subjected to enzymatic treatment combinations thereof (or extracts therefrom), could be used in to form an enzymatically-treated seed material. The enzy a cosmetic formulation. Extracts from Such tobacco plant matically-treated material then is subjected to solvent extrac components can include, for example, terpenes, sesquiterpe tion to form a seed extract. nes, diterpenes, esters (e.g., terpenoid esters and fatty acid 0050. In one embodiment, the separating or isolating pro esters), alcohols, aldehydes, ketones, carboxylic acids, lac cess comprises freezing a harvested seed or a portion thereof tones, anhydrides, phenols quinones, ethers, nitriles, amines, to formafrozen seed material, processing the frozen seed into amides, imides, nitroalkanes, nitrophenols, nitroarenes, a particulate form, Subjecting the particulate seed material to nitrogen-containing heterocyclics, lactams, oxazoles, aza an enzymatic treatment to chemically alter the particulate arenes, Sulfur-containing compounds, alkaloids (e.g., nico seed material, and extracting the particulate seed material tine), plastid pigments (e.g., chlorophylls or carotenoids), with a solvent to produce a seed extract. Exemplary enzy lipids (e.g., phytosterols), and derivatives thereof. Extracts matic treatments include treatment with a glycosidase or a from various portions of the tobacco plant can serve various glucocidase. functions within a cosmetic. Such as enhancement of sensory 0051 Refining tobacco seed oil can provide advantageous characteristics (e.g., by providing an aroma or flavor), serving compositions useful in the present invention. For example, in as a binder or filler, or otherwise augmenting or replacing various embodiments, raw oil comprises about 80% by conventional cosmetic ingredients. Various references in the weight triglyceride bound fatty acids and about 20% free fatty art teach methods of extracting or deriving components from acids. In contrast, refined oil can comprise about 96-99% tobacco, such as starch or sugar (U.S. Appl. Pub. Nos. 2012/ US 2014/0356295 A1 Dec. 4, 2014

0138074 to Cantrelletal. and 2012/0141648 to Mortonet al.), by weight, based on total weight of the cosmetic formulation. polymeric or bioplastic materials (U.S. Appl. Pub. Nos. 2012/ As described above, tobacco seed oil can be substituted for 0192882 to Dube et al. and 2012/0211016 to Byrd et al.), oils traditionally used in cosmetic compositions; however, glycerin (U.S. Appl. Pub. No. 2012/0260929 to Coleman et other essential and natural oils can be used in addition to al.), Various flavorful or aromatic compounds (U.S. Appl. tobacco seed oil in Some embodiments. Natural oils can Pub. No. 2012/0272976 to Byrd et al.), triacetin (U.S. Appl. include, for example, jojoba oil, Sweet almond oil, coconut Pub. No. 2012/0298.125 to Dube et al.), pectin (U.S. Appl. oil, shea butter, mango butter, and/or aloe Vera butter or mix Pub. No. 2013/0125904 to Chen et al.), microcrystalline cel tures thereof. Essential oils can be synthetic or natural. Natu lulose (U.S. application Ser. No. 13/451,032 to Byrd et al.), ral essential oils can include, for example, bergamot, chamo and proteins (U.S. application Ser. No. 13/830,063 to Mua et mile german, chamomile maroc, chamomile roman, al.), all of which are incorporated by reference herein. cinnamon Zeylanicum, clove buds, eucalyptus globulus, frankincense, fennel, hyssop, juniper, lemon grass, mountain Exemplary Cosmetic Adjuvants savory, niaouli, peppermint, red thyme, rosemary, rose gera 0055. In addition to tobacco seed extract (e.g., tobacco nium, tagestes, and ylangylang. seed oil), cosmetic compositions of the invention can com 0.058 Synthetic essential oils can include, for example, prise various other ingredients depending on the desired pur esters, such as acetylated castor oil, glyceryl Stearate, glyceryl pose of the composition. It should be understood that dioleate, glyceryl distearate, glyceryl trioctanoate, glyceryl although the following exemplary adjuvants may be identi distearate, glyceryl linoleate, glyceryl myristate, glyceryl fied as a certain type/class of adjuvant, or for a particular isostearate, PEG castor oils, PEG glyceryl oleates, PEG glyc purpose/function within the cosmetic composition, various eryl Stearates, PEG glyceryl tallowates, PEG-4 diheptanoate, ingredients have several purposes that may not be listed hydrogenated castor oil, isotridecyl isononanoate, isostearyl herein. Therefore, an adjuvant can serve multiple functions in neopentanoate, tridecyl neopentanoate, cetyl octanoate, cetyl a composition, despite the non-limiting classifications and palmitate, cetyl ricinoleate, cetyl Stearate, cetyl myristate, examples below. coco-dicaprylate/caprate, decyl isostearate, isodecyl oleate, 0056 Certain compositions of the present invention can isodecyl neopentanoate, isohexyl neopentanoate, tridecyl comprise an emulsifier, particularly where the cosmetic uses octanoate, octyl palmitate, dioctyl malate, tridecyl octanoate, the tobacco seed oil as at least a portion of the oily phase of an myristyl myristate, octododecanol; fatty alcohols such as emulsion. Emulsifiers, which can be synthetic or natural, can oleyl alcohol, isocetyl alcohol; and also silicone oils, isopar be useful to blendingredients that otherwise would be immis affins, hydrogenated polyisobutene, petrolatum, lanolin cible. Natural emulsifiers can include, for example, olive oil, derivatives, and sorbitan derivatives. Other natural and syn olive oil/wheat protein, olive oil/oat protein, Sucrose esters, thetic oils can be found in the Cosmetic Handbook and Per rice bran emulsifiers, and or various other food and pharma sonal Care Products Council ingredient information. ceutical grade emulsifiers, alone or in combination. Synthetic 0059 Embodiments of compositions according to the emulsifiers can include, for example, silicone emulsifiers, present invention also can include thickeners, which can be Such as dimethicone copolyols; Sulfonates and Sulfonic acids used to gel or thicken cosmetic compositions. In certain derivatives; phosphorous organic derivatives; Sugar esters; embodiments, thickeners can provide, for example, better fatty esters, such as Sorbitan monolaurate, Sorbitan Stearate, deposition properties of the cosmetic product. When present Sorbitan laurate, Sorbitan palmitate, Sorbitan oleate, cetearyl in the cosmetic composition, the thickening agent can be olivate, sorbitan olivate; polyesters/PEG (polyethylene gly included in an amount from about 0.01% to about 10%, col) derivatives, such as Polysorbate 20 (polyethylene glycol alternatively from about 0.1% to about 5%, by weight of the 20 sorbitan monolaurate); fatty acid esters of fatty alcohols, composition. Thickeners can be either synthetic or natural. Such as glyceryl Stearate, isopropyl Stearate, hexyl laurate; Natural thickeners can include waxes, gums and powders and fatty acid amides; acyl lactylates; alkoxylated compounds, mixtures thereof. Natural waxes can include, for example, Such as alkoxylated block polymers, alcohols, alkylphenols, beeswax, carnauba, and/or candelilla and mixtures thereof. amines, amides, fatty esters, fatty acids, oils, Sugar esters and Natural gums can include, for example, acacia, Xanthan, polyesters, fatty acid esters of fatty alcohols, and ethers of Schelortium (amigel), and/or cellulose and mixtures thereof. fatty alcohols; carboxylated alcohol ethoxylates and alky Natural powders can include, for example, clay, diatoma lphenol ethoxylates; carboxylic acids/fatty acids; bases Such ceous earth, fuller's earth, silica, silica shells or spherical as triethanolamine; fatty alcohols such as cetearyl alcohol, silica, fumed silica, spherical silica, hydrated silica, Silica and mixtures thereof. The total amount of an emulsifier con silylate, mica, titanated mica, talc, cellulose or spherical cel tained in the cosmetic formulations of the invention can vary. lulose beads, microcrystalline cellulose, corn starch, rice In some embodiments, an emulsifier will be present in an starch, glyceryl Starch, soy flour, walnut shell powder, agar, amount of about 0.01% by weight to about 20% by weight, or sericite, dextran, nylon, silk powder, chalk, calcium carbon about 0.1% to about 10% by weight, or about 0.5% to about ate, bismuth oxychloride, iron oxide, titanium dioxide, alu 5% by weight, based on the total weight of the formulation. minum silicate, magnesium aluminum silicate, calcium sili 0057 Compositions according to the present invention Cate, magnesium trisilicate, aluminum starch also can include one or more essential and natural oils. In octenylsuccinate, bentonite, hectorite, kaolin, maltodextrin, certain embodiments, the one or more oils is present in an montmorillonite, Zinc laurate, Zinc myristate, Zinc rosinate, amount of about 0.1% by weight to about 20% by weight, alumina, attapulgite, tin oxide, titanium hydroxide, trimag such as about 1% to about 10% by weight, based on the total nesium phosphate, or mixtures thereof. weight of the cosmetic formulation. In some embodiments, 0060 Synthetic thickeners can include, for example, AMP the amount of oils can be characterized as at least about 0.5% isostearoyl hydrolyzed collagen, AMP isostearoyl hydro by weight, at least about 1.0% by weight, at least about 1.5% lyzed wheat protein, ammonium acryloyldimethyltaurate VP by weight, at least about 2.0% by weight, or at least about 5% copolymer, cetyl hydroxyethylcellulose, chondroitin Sulfate, US 2014/0356295 A1 Dec. 4, 2014 cocoamidopropyldimethylamine Cs isoalkySuccinyl lacto ingredient information. When present in the cosmetic com globulin Sulfonate, cocodimonium hydroxypropyl hydro position, one or more Surfactants can be included in an lyzed collagen, distarch phosphate, ethyl ester of hydrolyzed amount from about 2% to about 50%, from about 5% to about animal protein, guar hydroxypropyltrimonium chloride, 30%, from about 10% to about 25%, or from about 1% to glyceryl polymethacrylate, hydrolyzed animal or plant pro about 10%, by weight of the composition. tein, hydroxypropyl guar, hydroxypropylmethyl cellulose, 0063) Non-limiting examples of suitable anionic surfac hydroxypropyl cellulose, isostearoyl hydrolyzed collagen, tants include alkyl and alkyl ether sulfates of the formula methylcellulose, nitrocellulose, nonoxynyl hydroxyethylcel ROSOM and RO(CHO), SOM, wherein R is alkyl or alk lulose, acrylate polymers, acrylamine polymers, acrylic acid enyl of from about 8 to about 18 carbonatoms, X is 1 to 10, and polymers (carbomer), PVMIMA Decadiene crosspolymers, M is a water-soluble cation Such as ammonium, Sodium, polyvinylpyrrolidone polymers, silicone oils, polyethylene potassium, and triethanolamine cation or salts of the divalent thickeners, aluminum starch octenyl Succinate, trihydroxyS magnesium ion with two anionic Surfactant anions. The alkyl tearin, and mixtures thereof. Other natural and synthetic ether Sulfates can be made as condensation products of eth thickeners can be found in the Cosmetic Handbook and Per ylene oxide and monohydric alcohols having from about 8 to sonal Care Products Council ingredient information. about 24 carbonatoms. The alcohols can be derived from fats 0061. As noted above, compositions according to the Such as coconut oil, palm oil, palm kernel oil, or tallow, or can present invention can include waxes. In some embodiments, be synthetic. These ingredients can be mixed with an alkaline Suitable waxes can have a melting point ranging from 35 to Substance, usually sodium hydroxide, or lye, to create a salt. 120° C., and include, for example, natural and synthetic Other suitable anionic surfactants include water-soluble salts waxes. When present in the cosmetic composition, a wax can of the organic, sulfonic acids of the general formula R'— be included in an amount from about 0.01% to about 10%, SOM), wherein R' is a straight chain aliphatic hydrocarbon alternatively from about 0.1% to about 5%, by weight of the radical having from 13 to 17 carbon atoms, and M is a water composition. Natural waxes can be, for example, esters of soluble cation Such as ammonium, Sodium, potassium, and fatty acids and a long chain alcohol. Natural waxes can triethanolamine cation or salts of the divalent magnesium ion include, for example, bayberry wax, beeswax, candelilla wax, with two anionic Surfactant anions. carnauba wax, hydrogenatedjojoba oil, hydrogenatedjojoba 0064. Anionic surfactants suitable for use herein include, wax, hydrogenated microcrystalline wax, hydrogenated rice for example, ammonium lauryl Sulfate, ammonium laureth bran wax, Japan wax, jojoba butter, jojoba oil, jojoba wax, sulfate, triethylamine laurylsulfate, triethylamine laureth sul mink, ouricury, ozokerite, rice bran, and/or shellac. In an fate, triethanolamine lauryl sulfate, triethanolamine laureth embodiment, the cosmetic composition comprises beeswax, Sulfate, monoethanolamine lauryl Sulfate, monoethanola which functions as a useful emollient and thickener. Synthetic mine laureth Sulfate, diethanolamine lauryl Sulfate, diethano waxes can include, for example, ceresin, cetyl esters (e.g., lamine laureth Sulfate, lauric monoglyceride Sodium Sulfate, cetyl palmitate or cetyl ester wax, both of which can replace Sodium lauryl Sulfate, Sodium laureth Sulfate, potassium lau spermaceti, a natural wax originally obtained from whales), reth Sulfate, sodium lauryl sarcosinate, sodium lauroyl sarco lanolin wax, microcrystalline wax, montan, montan acid wax, sinate, lauryl sarcosine, cocoyl sarcosine, ammonium cocoyl paraffin, PEG-6 beeswax, PEG-8 beeswax, polyolefin, sulfu Sulfate, ammonium lauroyl sulfate, sodium cocoyl Sulfate, rizedjojoba oil, synthetic beeswax (i.e., hydroxyoctacosanyl Sodium lauroyl Sulfate, potassium cocoyl Sulfate, potassium hydroxy Stearate), synthetic candelilla wax, synthetic car lauryl Sulfate, monoethanolamine cocoyl Sulfate, sodium nauba wax, synthetic Japan wax, synthetic jojoba oil, Syn trideceth sulfate, sodium tridecyl sulfate, sodium methyl lau thetic wax, Stearoxy dimethicone, dimethicone behenate, royl taurate, Sodium methyl cocoyl taurate, sodium lauroyl Stearyl dimethicone, and synthetic homo- and copolymer isethionate, sodium cocoylisethionate, Sodium laureth Sulfo waxes from the ethylene series or mixtures thereof, waxes Succinate, sodium laurylsulfo Succinate, sodium tridecylben obtained by Fischer-Tropsch synthesis, waxy copolymers Zene Sulfonate, sodium dodecyl benzene Sulfonate, Sodium and esters thereof, and silicone waxes. In some embodiments, C14-16 olefin sulfonate, and mixtures thereof. emulsifying waxes, a special group of synthetic waxes, can be 0065. In various embodiments, amphoteric surfactants incorporated into a cosmetic composition to serve primarily Suitable for use in cosmetic compositions can be broadly as an emulsifier as opposed to an emollient. Other natural and described as derivatives of aliphatic secondary and tertiary synthetic waxes can be found in the Cosmetic Handbook and amines in which the aliphatic radical can be straight or Personal Care Products Council ingredient information. branched chain and wherein one of the aliphatic substituents 0062 Embodiments of cosmetic compositions according contains from about 8 to about 18 carbon atoms and one to the present invention can comprise a surfactant, also contains an anionic group Such as carboxy, Sulfonate, Sulfate, referred to as a detersive component or Soap. The Surfactant phosphate, or phosphonate. In some embodiments, for can provide cleaning performance to the composition. In example, amphoteric Surfactants for use in the cosmetic com various embodiments, Surfactants can be used to enhance position comprise sodium 3-dodecyl-aminopropionate, lather Volume of a cosmetic composition. In some embodi Sodium 3-dodecylaminopropane Sulfonate, sodium lauryl ments, Surfactants can provide texture to the cosmetic prod sarcosinate, N-alkyltaurines, N-higher alkyl aspartic acids, uct. The Surfactant can comprise an anionic Surfactant, Zwit cocoamphoacetate, cocoamphodiacetate, lauroamphoac terionic or amphoteric Surfactant, or combinations thereof. etate, lauroamphodiacetate, and mixtures thereof. Various examples and descriptions of detersive Surfactants 0066. In some embodiments, Zwitterionic surfactants suit are set forth in U.S. Pat. Nos. 5,104,646, 6,106,609, and able for use in a cosmetic composition can be broadly 6,649,155; U.S. application Ser. No. 12/103,902; and U.S. described as derivatives of aliphatic quaternary ammonium, Appl. Pub. No. 2008/0206355, and are incorporated herein by phosphonium, and Sulfonium compounds, in which the ali reference in their entireties. Other surfactants can be found in phatic radicals can be straight or branched chain, and wherein the Cosmetic Handbook and Personal Care Products Council one of the aliphatic substituents contains from about 8 to US 2014/0356295 A1 Dec. 4, 2014

about 18 carbon atoms and one contains an anionic group lar phase surfactant also can comprise short chain Saturated Such as carboxy, Sulfonate, Sulfate, phosphate or phospho fatty acids such as capric acid and caprylic acid. Without nate. In some embodiments, for example, Zwitterionic Surfac being limited by theory, it is believed that the unsaturated part tants for use in the cosmetic composition comprise betaines of the fatty acid of alcohol or the branched part of the fatty Such as coco dimethyl carboxymethyl betaine, cocoami acid or alcohol acts to “disorder the surfactant hydrophobic dopropyl betaine, cocobetaine, lauryl amidopropyl betaine, chains and induce formation of lamellar phase. Examples of oleyl betaine, lauryl dimethyl carboxymethyl betaine, lauryl Suitable liquid fatty acids include oleic acid, isostearic acid, dimethyl alphacarboxy ethyl betaine, cetyl dimethyl car linoleic acid, linolenic acid, ricinoleic acid, elaidic acid, boxymethyl betaine, lauryl bis-(2-hydroxyethyl)carboxym arichidonic acid, myristoleic acid, palmitoleic acid, and mix ethyl betaine, stearyl bis-(2-hydroxypropyl)carboxymethyl tures thereof. Examples of suitable ester derivatives include betaine, oleyl dimethyl gamma-carboxypropyl betaine, lauryl propylene glycol isostearate, propylene glycol oleate, glyc bis-(2-hydroxypropyl)alpha-carboxyethyl betaine, and mix eryl isostearate, glyceryl oleate, polyglyceryl disostearate tures thereof. The sulfobetaines can include coco dimethyl and mixtures thereof. Examples of alcohols include oleyl sulfopropyl betaine, stearyl dimethyl sulfopropyl betaine, alcohol and isostearyl alcohol. Examples of ether derivatives lauryl dimethyl sulfoethyl betaine, lauryl bis-(2-hydroxy include isosteareth or oleth carboxylic acid; or isosteareth or ethyl)sulfopropyl betaine, and mixtures thereof. olethalcohol. The structuring agent may be defined as having 0067. In certain embodiments, cationic and nonionic sur melting point below about 25°C. In a preferred embodiment, factants can be used in cosmetic compositions. Cationic Sur tobacco seed oil can provide the Suitable liquid fatty acid (i.e., factants can be derived from amines that are protonated at the linoleic acid) necessary to induce a lamellar phase Surfactant. pH of the formulation, e.g. bis-hydroxyethyl lauryl amine, 0070. Non-limiting examples of other anionic, Zwitteri lauryl dimethylamine, lauroyl dimethylamidoproplylamine, onic, amphoteric, cationic, nonionic, or optional additional cocoylamidopropylamine, and the like. Cationic Surfactants Surfactants Suitable for use in the compositions are described can also be derived from fatty quaternary ammonium salts in McCutcheons, Emulsifiers and Detergents, 1989 Annual, Such as lauryl trimethylammonium chloride and lauroylami published by M. C. Publishing Co.; and U.S. Pat. Nos. 3,929, dopropyl trimethyl ammonium chloride. 678; 2,658,072; 2,438,091; 2,528,378; 2,658,072; 5,104,646 0068. Nonionic surfactants can comprise water soluble to Bolich Jr. et al., U.S. Pat. No. 5,106,609 to Bolich Jr. et al., components such as lauryl dimethylamine oxide, cocodim each of which is herein incorporated by reference. ethylamine oxide, cocoamidopropylamine oxide, laurylami 0071 Compositions according to the present invention dopropyl amine oxide, etc., or alkylpolyethoxylates such as can comprise preservatives. Preservatives can be either syn laureth-4 to laureth-7. Nonionic Surfactants can also comprise thetic or natural. In certain embodiments, preservatives can and water insoluble components such as cocomonoethanol be used to inhibit growth of undesirable microorganisms. amide, cocodiethanol amide, lauroylmonoethanol amide, Natural preservatives can include black currant fruit extract, alkanoyl isopropanolamides, and fatty alcohols such as cetyl aspen bark, radish root, and Sorbic acid, potassium Sorbate, alcohol and oleylachohol, and 2-hydroxyalkyl methyl ethers, alone or in combination. Synthetic preservatives can include, etc. In some embodiments of a cosmetic composition, non for example, Sodium hydroxymethylglycinate, tetrahexylde ionic Surfactants can be selected from the group consisting of cylascorbate, tocopheryl acetate, phenoxyethanol, methylpa glucose amides, alkyl polyglucosides, Sucrose cocoate, raben, ethylparaben, propylparaben, imidazolidinyl urea, dia Sucrose laurate, alkanolamides, ethoxylated alcohols and Zolidinyl urea, DMDM hydantoin, isothiazolinones, mixtures thereof. In one embodiment the nonionic Surfactant chlorinated aromatic compounds, para-hydroxybenzoic is selected from the group consisting of glyceryl monohy acids/parabens, alone or in combination. In various embodi droxyStearate, isosteareth-2, trideceth-3, hydroxy Stearic ments, the cosmetic composition can include disodium eth acid, propylene glycol stearate, PEG-2 stearate, PEG-100 ylenediaminetetraacetic acid (EDTA). It is believed that diso Stearate, Sorbitan monostearate, glyceryl laurate, laureth-2, dium EDTA can bind to metal ions and inactivate them, cocamide monoethanolamine, lauramide monoethanola thereby preventing deterioration of the cosmetic product, pro mine, and mixtures thereof. In some embodiments, the cos tecting fragrance compounds, and preventing rancidity. Other metic composition can comprise polysorbate 60. natural and synthetic preservatives can be found in the Cos 0069. In some embodiments, the surfactant can be in the metic Handbook and Personal Care Products Council ingre form of a lamellar phase. It is proposed, without being limited dient information. When present in the cosmetic composi by theory, that a lamellar phase can provide resistance to tion, one or more preservatives can be included in an amount shear, adequate yield to suspend particles and droplets, desir from about 0.01% to about 20%, alternatively from about able rheology characteristics, and/or long term stability. 0.1% to about 10%, alternatively from about 0.1% to about Therefore, lamellar compositions can be desirable, especially 5%, and alternatively from about 0.5% to about 3%, by for Suspending emollient and for providing consumeraesthet weight of the composition. ics. The lamellar phase tends to have a viscosity that mini 0072. In various embodiments, the cosmetic composition mizes the need for viscosity modifying agents, however, can comprise an additional component such as an anti-dan lamellar compositions can be more expensive and generally druff agent that is physically and chemically compatible with require more surfactant. As disclosed U.S. Pat. No. 5,952.286 the essential components of the composition, for example. to Kolodzie et al., herein incorporated by reference, certain Examples of anti-dandruff agents include, but are not limited liquid fatty acids (e.g., long chain, unsaturated and/or to, antimicrobial actives, pyridinethione salts, azoles, sele branched fatty acids); long chain, unsaturated and/or nium sulfide, particulate Sulfur, keratolytic acid, salicylic branched alcohols (e.g., oleyl alcohol or isostearyl alcohol) or acid, octopiroX (piroctone olamine), coal tar, and combina derivatives (ester of fatty acids and ether of fatty acids) of tions thereof. Pyridinethione anti-dandruff agents are these fatty acids and/or alcohols can be used in a typical described, for example, in U.S. Pat. No. 2,809,971; U.S. Pat. rod-micellar Solution and induce a lamellar phase. The lamel No. 3,236,733; U.S. Pat. No. 3,753, 196; U.S. Pat. No. 3,761, US 2014/0356295 A1 Dec. 4, 2014

418; U.S. Pat. No. 4,345,080; U.S. Pat. No. 4,323,683: U.S. used in cosmetic compositions include acetyl tetrapeptide-5. Pat. No. 4,379,753; and U.S. Pat. No. 4,470,982, each of acetamide MEA, agarose, ammonium lactate, arginine PCA, which is herein incorporated by reference. Other anti-dan betaine, butylene glycol, copper PCA, corn glycerides, dig druff agents can be found in the Cosmetic Handbook and lycereth-7 malate, diglycerin, dimethyl imidazolidinone, Personal Care Products Council ingredient information. erythritol, gelatin, glycose, glycuroinc acid, glycuronolac When present in the cosmetic composition, the anti-dandruff tone, glutamic acid, glycereth-12, glycerin, honey extract, agent can be included in an amount from about 0.01% to hylauronic acid, hydroloyZed wheat starch, hydroxyethyl sor about 5%, alternatively from about 0.1% to about 3%, and bitol, lactamide, lactic acid, maititil, melibiose, panthenol, alternatively from about 0.3% to about 2%, by weight of the pantolactone, PCA, polyglycuronic acid, polyglyceryl composition. methacrylate, propylene glycerol, saccharide hydrolysate, 0073. Various embodiments of the cosmetic composition sea salt, seasame amino acids, Sodium aspartate, Sodium lac can comprise one or more conditioning agents. Conditioning tate, sodium malate, Sodium PCA, sodium polyaspartate, Sor agents can include materials which are used to give a particu bitol, TEA-lactate, triglycereth-7 citrate, urea, Xylose, glycyr lar conditioning benefit to hair and/or skin Conditioning rhiza glabra (Licorice) root extract and combinations thereof. agents useful in cosmetic compositions can comprise a water Other humectants can be found in the Cosmetic Handbook insoluble, water-dispersible, non-volatile, liquid that fauns and Personal Care Products Council ingredient information. emulsified, liquid particles. Non-limiting examples of condi The humectants can be present in an amount by weight of the tioning agents include allantoin, Xanthan gum, Saturated composition from about 0.1% to about 20%, or from about methylene diphenyldiisocyanate (SMDI) copolymers (e.g., 0.1% to about 10%, and alternatively from about 0.5% to PPG-12/SMDI copolymer which is a copolymer of PPG-12 about 5%. and SMDI monomers), materials characterized generally as 0076 Various embodiments of cosmetic compositions can silicones (e.g., silicone oils, cationic silicones, silicone gums, comprise an occlusive component. It is believed, without high refractive silicones, and silicone resins), organic condi being limited by theory, that occlusives can increase the water tioning oils (e.g., hydrocarbon oils, polyolefins, and fatty content of the skin by slowing the evaporation of water from esters) or combinations thereof, or those conditioning agents the Surface of the skin. In certain embodiments, occlusives which otherwise form liquid, dispersed particles in an aque can be greasy and can be most effective when applied to damp ous Surfactant matrix. Other conditioning agents can be found skin. In various embodiments, an occlusive component com in the Cosmetic Handbook and Personal Care Products Coun prises mineral oil. However, in some embodiments, mineral cil ingredient information. When present in the cosmetic oil can be less effective at preventing evaporation of water composition, the conditioning agent can be included in an than other occlusives. In some embodiments, an occlusive amount from about 0.01% to about 10%, alternatively from component comprises lanolin. However, lanolin can be about 1.0% to about 5%, and alternatively from about 0.01% expensive and potentially irritating. In some embodiments, an to about 1%, by weight of the composition. occlusive component comprises at least one silicone deriva 0074. Some embodiments of cosmetic compositions can tive (e.g., dimethicone and cyclomethicone). In certain comprise a Suspending agent. The Suspending agent can be embodiments, silicone derivatives can be less greasy, but they present at concentrations effective for Suspending water-in can also have a limited moisturizing effect. Non-limiting soluble material in dispersed faun in the cosmetic composi examples of occlusives useful in cosmetic compositions tion. In some embodiments, the Suspending agent can be include acetylated castor oil, acetylatedlanolin alcohol, behe present at concentrations effective for modifying the Viscos nyl isostearate, beeswax, C12-18 acid triglyceride, C20-40 ity of the cosmetic composition as desired for the final cos alcohols, C20-40 alkyl dimethicone, C16-36 alkyl stearate, metic product. Such concentrations can range from about C18-70 isoparaffin, C20-24 olefin, C10-18 triglycerides, can 0.1% to about 10% or about 0.5% to about 5.0% by weight of delilla, canola oil, caprylic/capric triglyceride, carnauba, cet the composition. Suspending agents useful in the present earyl methicone, cetyl ricinoleate, cholesteryl oleate, invention include, for example, crystalline Suspending agents cyclomethicone, decyl myristate, dimethicone, distearyl which can be categorized as acyl derivatives, long chain ether, glycol dioleate, hexyldecyl isostearate, hydrogenated amine oxides, and mixtures thereof. Examples of Such sus castor oil, hydrogenated lanolin, isocetyl myristate, lanolin pending agents are described in U.S. Pat. No. 4,741,855, linoleate, lauryl cocoate, lecithin, mineral oil, myristyl herein incorporated by reference in its entirety. Suspending myristate, neatsfool oil, octyldodecyl Stearate, oleyllinoleate, agents can also include, for example, ethylene glycol esters of palm kernel wax, paraffin, pentaerythrityl tetracocoate, petro fatty acids having from about 16 to about 22 carbon atoms, leum, propylene glycol dioleate, shark liver oil, soybeanlipid, ethylene glycol Stearates, mono and distearate, distearate Stearyl Stearate, squalane, tall oil, tocopherol, trihexyldecyl containing less than about 7% of the mono Stearate, and citrate, trisoStearin, , and combinations thereof. combinations thereof. Other Suspending agents can be found Other occlusives can be found in the Cosmetic Handbook and in the Cosmetic Handbook and Personal Care Products Coun Personal Care Products Council ingredient information. In cil ingredient information. Some embodiments, occlusives can be present at concentra 0075 Various embodiments of cosmetic compositions can tions effective for modifying the cosmetic composition as comprise at least one humectant. A humectant can function, desired for the final cosmetic product. Such concentrations for example, to attract and retain moisture in the airby absorp can range from about 0.1% to about 10% or about 0.5% to tion. A humectants can be considered, for example, a Sub about 5.0% by weight of the composition, for example. stance that can be used to keep things moist. Humectants 0077. In various embodiments of cosmetic compositions, useful in cosmetic compositions of the present invention can the composition can comprise an emollient. In various be selected from the group consisting of polyhydric alcohols, embodiments, emollients can act as lubricants and thereby water soluble alkoxylated nonionic polymers, and mixtures help maintain the soft, Smooth and pliable appearance of skin thereof. Non-limiting examples of humectants that can be and/or hair. Non-limiting examples of emollients useful in US 2014/0356295 A1 Dec. 4, 2014

cosmetic compositions include acetylated lanolin, acetyl tri extract can function, for example, as an antioxidant that can hexyl citrate, avocado sterois, butyl myristate, C14-15 alco provide anti-aging benefits in cosmetic compositions. In hols, C12-13 alkyl ethylhexanoate, caprylylglycol, castor oil, Some embodiments, palmitoyltetrapeptide-7 can be useful in cetyl acetate, cetyl oleate, C14-16 glycol palmitate, C12-20 reducing the appearance offine lines and wrinkles by enhanc isoparaffin, C12-15 alkyl benzoate, cyclomethicone, decyl ing collagen and hyaluronic acid production. In certain oleate, diethylhexyl adipate, diethylhexyl malate, diisodecyl embodiments, hesperidin methylchalcone can be useful in adipate, diisopropyl dilinoleate, dimethicone copolyol. reducing dark circles under the eye. Steareth-20-dipeptide-2 dipropyl adipate, ethylhexyl palmitate, ethyl linoleate, glyc is another compound that can function to reduce dark circles eryl dioleate, glyceryl ricinoleate, glyceryl Stearates, glycol under the eye, for example. Certain embodiments of cosmetic palmitate, glycol Stearate, hexyl laurate, isocetyl alcohol, iso compositions comprise polyacrylamide. Polyacrylamide can, decyl Stearate, isohexyl palmitate, isopropyl isoStearate, iso for example, dry to formathin coating on skin or hair, thereby propyl myristate, isopropyl palmitate, isostearyl alcohol, helping hair hold style by inhibiting the hairs ability to absorb jojoba oil, lanolin, methyl palmitate, myristyl propionate, moisture and helping retain skin products on the skin after octyl octanoate, octyl stearate, PEG-4 lanolate, PEG-5 immersion in water (e.g., Sunscreen). When present in a cos tristearyl citrate, polyglyceryl-6 oleate, plyglycerol-2 triisos metic composition, each of these additional ingredients can tearate, PPG-20 cetyl ether, PPG-4 laureth-2, propylene gly be present in an amount of about 0.01% to about 5%, alter collinoleate, sodium hyaluronate, squalene, Sucrose oleate, natively from about 0.1% to about 3%, and alternatively from Sunflower seed oil glycerides, tall oil glycerides, tridecyl about 0.1% to about 1%, by weight of the composition. Stearate, wheat germ glycerides, glycyrrhiza glabra (Lico rice) root extract, aloe barbadensis leaf juice, and combina Hair Treatment Products tions thereof. Other emollients can be found in the Cosmetic 0080 Shampoo is a hair care product that can be used for Handbook and Personal Care Products Council ingredient the removal of oils, dirt, skin particles, dandruff, environmen information. When present in the cosmetic composition, one tal pollutants and other contaminant particles that gradually or more emollients can be included in an amount from about build up in hair. Many modern shampoos further include a 0.01% to about 20%, alternatively from about 0.1% to about conditioning component used to Smooth and detangle hair 10%, and alternatively from about 0.5% to about 5%, by that has been washed with shampoo. Common ingredients weight of the composition. found in hair care products include vitamins and provitamins, 0078. In various embodiments, pigments can be used to botanical extracts, a LTV protectant, fruit acids or alpha provide color to the final cosmetic composition. Pigments can hydroxy acids, antioxidants, water, humectants, a Surfactant be synthetic or natural. Natural pigments can include pig (also referred to as a detergent), an emulsifier, preservatives, ments or plant-derived colors, for example. Natural pigments Solvents, and combinations thereof. Examples of common can be inorganic (mineral) or organic, white or non-white, detergent-type ingredients useful in a shampoo composition and coated or uncoated particles, for example Natural pig include ammonium lauryl Sulfate, sodium laureth Sulfate (de ments can include, for example, cerium oxide, iron oxide, rived from coconut oils and can be useful, for example, to titanium dioxide, Zinc oxide, Zirconium oxide, carbon black, soften water and create a lather), Sodium lauroamphoacetate manganese violet, ultramarine blue, D&C and FD&C colors, (derived from coconut oils and can be useful, for example, as azo, indigoid, insoluble metallic salts of certified color addi a cleanser and a counter-irritant), and Sodium lauryl Sulfate. tives, and the like, and mixtures thereof. Other pigments can Other Surfactants that can be useful in a shampoo composition be found in the Cosmetic Handbook and Personal Care Prod include, for example, cocamideopropyl betaine, glycol, ucts Council ingredient information. When present in the polysorbate 20 (PEG(20)) (can be useful, for example, to cosmetic composition, pigments can be included in an solubilize fragrance oils and essential oils), and polysorbate amount from about 0.01% to about 5%, alternatively from 80 (PEG(80)) (can be useful, for example, to emulsify oils in about 0.1% to about 3%, and alternatively from about 0.1% to water). In addition, thickeners can be useful in shampoo about 2%, by weight of the composition. compositions. PEG-150 distearate is an example of a thick 0079. Some embodiments of cosmetic compositions can ener that can be used in hair treatment compositions. In vari include additional ingredients useful for treating skin and/or ous compositions, Sodium chloride can be used as a thickener hair. For example, some embodiments comprise cholecalcif if the main Surfactants are sodium lauryl Sulfates. In various erol (also referred to as Vitamin D). Cosmetic compositions compositions, ammonium chloride can be used to thicken the can comprise coenzyme Q10, pomegranate (punica grada composition if the Surfactants are ammonium based. tum) extract, and lipoic acid, either alone or in combination, Examples of conditioning-type components that can be use for example. In certain embodiments, these agents can func ful in hair treatment products include guar hydroxypropyltri tion as an antioxidant, for example. Embodiments of a cos monium chloride, dimethicone, silicone, and polyduater metic composition can comprise cholecalciferol. Cholecal nium-10. Examples of preservatives useful in shampoo ciferol can function as an antioxidant and anti-inflammatory compositions include citric acid, quatemium-15 and methyl agent, for example. Cosmetic compositions can comprise isothiazolinone (MIT). witch hazel extract. In some embodiments, witch hazel 0081. As discussed above, a tobacco seed extract can also extract is useful as an anti-inflammatory agent, for example. provide an advantageous source of linoleic acid in cosmetic Some embodiments of cosmetic compositions can comprise products. Tobacco seed oil can replace the oil components palmitoyl pentapeptide-4, PEG-8 oligopeptide, green tea conventionally used in hair treatment products. The high con extract, palmityol tetrapeptide-7. hesperidin methylchalcone, centration of linoleic acid of the tobacco seed oil can provide steareth-20-dipeptide-2, and combinations thereof. Palmitoyl beneficial effects on skin and hair, and can also function as an pentapeptide-4 can function, for example, as a skin rejuvena effective and efficient emollient and/or surfactant in hair tion, anti-wrinkle compound. In some embodiments, PEG-8 treatment composition. Furthermore, the resulting composi oligopeptide can be useful for treating wrinkles Green tea tions incorporating tobacco seed oil are found to have the US 2014/0356295 A1 Dec. 4, 2014

same sensory characteristics and general appearance has tra hair treatment products, thickeners include Xanthan gum, ditional hair treatment products incorporating emollients and cetyl alcohol, sodium chloride, and stearyl alcohol. Many of Surfactants known in the art. these chemical compounds further act as conditioning agents I0082. As described in U.S. Appl. Pub. No. 2013/0090279, on the hair. Some embodiments of hair treatment composi herein incorporated by reference in its entirety, a detersive tions comprise other conditioners such as allantoin and glyc Surfactant may be selected from an anionic detersive Surfac erin, for example. tant, Zwitterionic, or an amphoteric detersive Surfactant, or a I0086 Specialty shampoos, such as baby shampoo, curling combination thereof. Suitable anionic Surfactant components shampoo, dandruff shampoo, and other types of shampoos for use in the composition herein include those which are can comprise additional additives. Various embodiments of known for use in hair care or other personal care shampoo shampoo compositions further comprise components that compositions. In one embodiment, the anionic Surfactant may provide ultraviolet light protection, proteins, vitamins, plant be a combination of Sodium lauryl Sulfate and Sodium lau extracts, other organic ingredients, and combinations thereof. reth-n Sulfate, for example. The concentration of the anionic In an embodiment, a Sunscreen component used in a hair Surfactant component in the shampoo should be sufficient to treatment composition can be octyl salicylate and/or PABA, a provide the desired cleaning and lather performance, and compound found in various Sunscreen lotions. generally ranges from about 2% to about 50%, from about 8% I0087 Various embodiments of hair treatment composi to about 30%, from about 10% to about 25%, or from about tions can comprise hydrophobic moisturizing materials 12% to about 22%. Suitable amphoteric or Zwitterionic deter selected from the group consisting of petrolatum, lanolin, sive surfactants for use in a hair treatment composition hydrocarbon oils such as mineral oil, natural and synthetic include those which are known for use in hair care or other waxes such as microcrystalline waxes, paraffins, oZokerite, personal care cleansing. Concentrations of Such amphoteric lanolin wax, lanolin alcohols, lanolin fatty acids, polyethyl or Zwitterionic detersive surfactants can range from about ene, polybutene, polydecene and perhydrosqualene, Volatile 0.5% to about 20%, alternatively from about 1% to about or non-volatile organosiloxanes and their derivatives Such as 10%. Non-limiting examples of suitable Zwitterionic or dimethicones, cyclomethicones, alkyl siloxanes, polymeth amphoteric Surfactants are described above. ylsiloxanes and methylphenylpolysiloxanes, lanolin oil, 0083 Various embodiments of hair treatment composi esters such as isopropyl lanolate, acetylated lanolin, acety tions further include lather builders. In some embodiments, lated lanolin alcohols, lanolin alcohol linoleate, lanolin alco lather builders, or co-surfactants, can comprise materials hol riconoleate natural and synthetic triglycerides Such as which are combined with the undecyl sulfate surfactant and castor oil, soybean oil, Sunflower seed oil, maleated soybean optionally anionic Surfactants to enhance lather Volume and/ oil, safflower oil, cotton seed oil, corn oil, walnut oil, peanut or to modify lather texture. Lather builders can serve to pro oil, olive oil, cod liver oil, almond oil, avocado oil, palm oil duce faster lather, facilitate easier rinsing, and/or mitigate and sesame oil, castor oil derivatives, Sefoses, and combina harshness on the keratinous tissue. They can further aid in tions thereof. As discussed above, essential oils useful in producing lather having a more desirable texture, Volume cosmetic compositions can beneficially comprise tobacco and/or other properties. These materials can be selected from seed oil. Essential oils can, for example, increase the effec a variety of families of structures including, but not limited to, tiveness of hair treatment compositions. amphoteric, Zwitterionic, cationic, and nonionic Surfactants. These chemical compounds can help create the Suds, which Cleansers can help the detergents to work better by allowing more dirt to I0088 Body and facial cleansers can be designed to clear be lifted from the hair and washed away. They can be used away dirt and grime from the skin. Many cleansers can also with anionic Surfactants in a weight ratio of 1:20 to 1:4, and serve to moisturize the skin, sooth irritated skin, reduce the alternatively in the 1:12 to 1:7 weight ratio. Embodiments of signs of aging or repair damaged facial skin. Many cleansers hair treatment compositions of the present invention may contain similar basic ingredients. A tobacco seed extract can comprise from about 0.5 wt % to about 10 wt %, alternatively provide an advantageous source of linoleic acid by replacing, from about 0.5 wt % to about 5 wt %, alternatively from about for example, an oil component, an emollient, an anti-aging 0.5 wt % to about 3 wt %, alternatively from about 0.5 wt % agent, and/or a surfactant in cleansing products. The high to about 2 wt %, and alternatively from about 0.5 wt % to concentration of linoleic acid of the tobacco seed oil can about 1.75 wt % by weight of the composition of at least one provide beneficial effects on skin, particularly when dealing suitable lather builder. In some embodiments, lather builders with problems such as acne, dryness, and Swelling. In certain incorporated in shampoo or other cleansing cosmetic compo embodiments, cleansing products incorporating tobacco seed sitions comprise cocamide mea, lauramide diethanolamide oil can provide an antioxidant and an anti-inflammatory and/or cocamidopropyl betaine, for example. effect, and the tobacco seed oil can further function as an 0084. Many detergents are alkaline or base compounds, emollient and/or surfactant. Furthermore, the resulting com which can make the hair look dull. Various embodiments of positions incorporating tobacco seed oil are generally found hair treatment products can include acids. Acids can function to have the same or similar sensory characteristics and to keep the hair looking shiny, for example. Commonly used appearance as traditional cleansing products incorporating acids in shampoos include ascorbic acids and citric acid, for for example, oils, anti-aging agents, emollients and Surfac example. Collagen (e.g., hydrolyzed collagen) can also be tants known in the art. included in certain hair treatment compositions. Collagen I0089. In general, cleansers comprise some faun of surfac can, for example, enhance the hair body, Suppleness and/or tant (i.e., a Soap or detergent). Facial cleansers tend to be sheen of the hair. milder on the skin because the Surfactant they contain is 0085 Many hair treatment compositions also include milder than that of body cleansers. Some liquid body cleans thickening agents. Thickeners can ensure that the product is ers can incorporate moisturizing agents to compensate for a thick and creamy, for example. In various embodiments of harsher Surfactant used. The moisturizing agent can comprise US 2014/0356295 A1 Dec. 4, 2014

emollients, such as linoleic acid, for example. Cleansers for blocking agent, a Wetting agent, essential oil, dyes, pigments, the skin can generally be divided into three main types: foam a hydrophilic or lipophilic activator, lipid vesicles, or the like. ing cleansers, non-foaming cleansers and abrasive scrubs. These additives may be included in an amount commonly 0090. Foaming cleansers can provide a pleasing feel used in the cosmetic or dermatological field. because in certain embodiments, they lather and leave behind 0096. A lotion can be a low to medium viscosity topical a refreshing sensation after they are rinsed off. Foaming facial preparation intended for application to unbroken skin. cleansers can include, for example, lotions, creams, gels, Creams and gels can have higher viscosity. Many lotions and self-foaming cleansers, arerosols, scrubs, etc. creams are intended to Smooth, re-hydrate, and soften the 0091. Non-foaming cleansers can be a mild type of skin. Categories of ingredients useful in skin moisturizers can cleanser. In certain embodiments, non-foaming cleansers include: humectants, emollients and preservatives. Humec contain Small amounts of Surfactant and can be wiped off tants, such as urea, glycerin, and alpha hydroxyl acids, can instead of rinsed off. In some embodiments, non-foaming help absorb moisture from the air and hold it in the skin, for cleansers are not intended to come in contact with water, and example. Emollients, such as lanolin, mineral oil and petro thereby they can deposit more of the helpful ingredients onto latum, can help fill in spaces between skin cells, lubricating the skin. Non-foaming cleansers can include creams, lotions and Smoothing the skin, for example. Preservatives can help (sometimes referred to as milks), and cold creams. prevent bacteria grown in moisturizers. Other ingredients can 0092 Abrasive scrubs can contain ingredients that physi include vitamins, minerals, plant extracts, and fragrances, for cally scrub the skin to help remove dead skin cells, thereby example. leaving the skin Smoother. However, the granules that do the 0097. In various embodiments, humectants can attract actual scrubbing can cause irritation, redness, and even tiny water from the dermis into the epidermis, increasing the water cuts on the face. Therefore, it can be advantageous to incor content in the epidermis. It is believed, without being limited porate a moisturizing agent into the abrasive Scrub. Non by theory, that humectants can also attract water from the limiting examples of exfoliating granules include Sodium atmosphere into the epidermis. In various embodiments of tetraborate decahydrate granules, polyethylene silica or body and facial moisturizing compositions, a humectant beads, jojoba esters, cross-linked polymethacrylate, calcium component can comprise ammonium lactate, butylene glycol, carbonate, ground seeds (e.g., apricot, almond and walnut propylene glycerol, glycerin, hylauronic acid, sodium pyr seeds), aluminum oxide and combinations thereof. rolidone carboxylic acid (PCA), sorbitol, urea, and combina tions thereof. Humectants, for example glycerin, can provide SkinTreatment Products Smoother-looking skin. 0093 Skin in general is composed of three distinct layers: 0.098 Emollients can be ingredients that can remain in the the outer protective straum coreum; the middle epidermis stratum coreum to act as lubricants. In various embodiments, layer and the inner dermis layer. Sweat glands and hair roots emollients can help maintain the Soft, Smooth, and pliable are found in the dermis layer. As discussed above, a tobacco appearance of the skin. Emollients can be oil-based or water seed extract can replace components conventionally used in based. Oil-based emollients can be heavier and may leave a cosmetic products. The high concentration of linoleic acid of residue on skin, and therefore these can be beneficial for dry the tobacco seed oil can provide beneficial effects on skin, skin that requires intense moisturizing, for example. Water particularly when dealing with problems such as acne, dry based emollients can be lighter and less greasy, which can ness, and Swelling. In certain embodiments, cosmetic prod make them ideal for normal, oily or acne-prone skin. In vari ucts incorporating tobacco seed oil can also be effective emol ous embodiments of moisturizing compositions, an emollient lients, antioxidant and anti-inflammatory agents. can comprise cyclomethicone, dimethicone copolyol, glyc Furthermore, the resulting compositions incorporating eryl Stearates, propylene glycol linoleate, isopropyl palmi tobacco seed oil are found to have the same sensory charac tate, lanolin, and combinations thereof. As discussed above, teristics and general appearance has traditional skin treatment emollients useful in cosmetic compositions can comprise products incorporating for example, anti-aging agents, emol tobacco seed oil. Tobacco seed oil can provide a relatively lients and anti-inflammatory agents known in the art. high percentage of linoleic acid, which can have beneficial 0094. In various embodiments of cosmetic compositions effects on skin as discussed above. intended for use on the skin, the composition can comprise a 0099. Additional ingredients can be added to moisturizers cosmetically or dermatologically acceptable medium or base. to create a special effect on the skin Such as enhancing the The composition can be provided in the form of any topically appearance of dry or damaged skin. Chemicals that slow applicable formulations, for example, a solution, a gel, a oxidation by reacting with free radicals include tocopherols Solid, an anhydrous paste, an oil-in-water emulsion, a suspen and ascorbic acid, for example. It is proposed, without being Sion, a micro emulsion, a microcapsule, a micro granule, an limited by theory, that although citric acid, tartaric acid, and ionic (liposome) or nonionic vesicular dispersion, a cream, a EDTA may not have strong antioxidating properties, they can skin lotion, a milk lotion, a powder, an ointment, a spray or a enhance the antioxidant effects of other ingredients. As dis conceal stick. These compositions can be prepared according cussed above, linoleic acid has many beneficial properties in to any convention method known in the art. a variety of moisturizing compositions. 0095. The composition for skin application according to 0100 Various embodiments of cosmetic products can be the present invention can contain additives commonly used in intended to treat undesirable facial lines, wrinkles, and/or the cosmetic or dermatological field, for example, fat, an dark circles under the eyes. Embodiments of this type of organic Solvent, a solubilizing agent, a concentrating agent, a cosmetic composition can comprise one or more of three gelling agent, a softener, an antioxidant, a Suspending agent, ingredients: retinol, Vitamin K and Vitamin C. a stabilizer, a foaming agent, an aromatic, a surfactant, water, 0101 Retinol and/or retinyl palmitate (ester of retinol and an ionic or non-ionic emulsifier, a filler, a metal ion seques palmitic acid) can each be useful as an anti-wrinkle agent. It tering agent, a chelating agent, a preservative, Vitamins, a is believed to be able to greatly reduce the fine lines and US 2014/0356295 A1 Dec. 4, 2014 wrinkles that appear around they eye, for example. Retinol is is advantageous for product incorporation as free fatty acids a biological form of Vitamin A. Without being limited by are subject to oxidation and eventual rancidity. theory, Retinol is believed to be able to even out the skins complexion and make the skin appear more luminous. It is Example 2 also thought that Retinol can penetrate the outermost layers of the skin's Surface, getting underneath to plump up and 0.108 Storage and stability testing is performed on various brighten the dermal layer. Furthermore, retinol is believed to embodiments of cosmetic products incorporating tobacco also function as an antioxidant and promote new skin cell seed oil. The incorporation of the tobacco seed oil does not growth. Therefore, it is thought of as an efficient and effective pose any unusual problems or issues when preparing formu wrinkle reducer, fine line eraser and pigmentation stabilizer. lations. The material is relatively easy to incorporate and is However, retinol is frequently associated with consumer dis essentially comparable to Argan oil. comfort characterized by burning, stinging, itching or sensa 0109 Stability testing (e.g., testing at 45° C., Freeze/thaw tion of tightness after application. Therefore, linoleic acid can testing, testing at 4°C. and testing at room temperature) does be a good Substitute for an anti-wrinkle agent in cosmetic not show any color or odor issues and no noticeable adverse compositions, as discussed above. effect on product integrity. Argan oil and tobacco seed oil 0102. It is proposed, without being limited by theory, that behave in similar manners. Theodor of the tobacco seed oil is Vitamin K, also known as Phytonadione, can enhance col very low and does not appear to go 'rancid' or adversely lagen development in the skin, thus plumping up the area affect the formulations prepared under stability test condi under the eyes and decreasing dark circles. It is thought that tions. Vitamin K can also help with increased blood circulation 0110. In a Shampoo/Body Washformula, the tobacco seed which can enhance skin appearance. It can renew damaged oil does not appear to have any adverse effect on foaming as skin, for example damage from the Sun's rays, lack of sleep, compared to the Argan oil. From a practical use assessment, genetics, aging or other causes. Vitamin K can improve the there does not appear to be any major formulation challenges strength of these blood vessel walls, making them less visible that would prevent use of tobacco seed oil in skin care and hair underneath the skin (e.g., reducing dark circles under the care formulations. eyes). 0103. It is proposed, without being limited by theory, that Example 3 Vitamin C, or ascorbic acid, also aids in strengthening the 0111. As shown in Table 1, tobacco seed oil is incorpo walls of these blood vessels. It is believed that an added rated into a facial moisturizer. The tobacco seed oil replaces benefit of Vitamin C for dark circles and lines under the eyes Sunflower seed oil, olive oil and grape seed oil in the product is an increase in collagen or plumping of the under-eye area. composition. The resulting product has sensory characteris It is further proposed that Vitamin C can be used to defuse free tics similar to the characteristics of a comparable composition radicals and counterbalance the negative effects of exposure containing the replaced ingredients. to UV rays. A lightening of the skin can be provided with the use of Vitamin C as an ingredient in eye cream compositions. TABLE 1 In some embodiments, tetrahexyldecyl ascorbate, a stable, oil-soluble Vitamin Cester which can have antioxidant activ Night Facial Moisturizer ity, for example, can be included in the cosmetic composition. Ingredient Name Weight% EXPERIMENTAL Deionized Water 20-80 Tobacco Seed Oil 1-5 0104 Aspects of the present invention are more fully illus Aloe Barbadensis Leaf Juice 2-5 trated by the following examples, which are set forth to illus Glycerin 2-5 Stearic Acid O-5 trate certain aspects of the present invention and is not to be Glyceryl Stearate O-5 construed as limiting thereof. Glycyrrhiza Glabra (Licorice) Root Extract O-5 Butyrospermum Parkii (Shea Butter) O-5 Example 1 Phenoxyethanol O-5 Sodium Hyaluronate O-5 0105. The following non-limiting example describes how Carbomer O-5 Cetyl Alcohol O-5 tobacco seed oil can be extracted and refined for purposes of Collagen O-5 the invention. Isodecyl Neopentanoate O-5 0106 Tobacco seeds are harvested from field grown plants Panthenol O-5 Triethanolamine O-5 and extracted with hexane and agitation. The defatted seed C12-15 Alkyl Benzoate O-5 cake is removed from the hexane extract by simple filtration. Tetrahexyldecyl Ascorbate O-2 The extract is then placed in a distillation apparatus, which Tocopheryl Acetate O-2 separates the hexane from the tobacco seed oil. Bergamot Extract O-3 Disodium EDTA O-1 0107 The raw oil derived from these processes comprises Retinyl Palmitate O-1 approximately 20% by weight free fatty acids, and 80% by Cholecalciferol O-1 weight triglyceride bound fatty acids, comprising primarily Allantoin O-1 linoleic acid (-70% by weight). The free fatty acids are then removed by a refinement process that consists of an acidic wash (citric acid) followed by a base wash (sodium hydrox Example 4 ide) and Subsequent centrifugation. The resulting refined oil is approximately 4% by weight free fatty acids and 96% 0112. As shown in Table 2, tobacco seed oil is incorpo triglyceride bound fatty acids. A lower free fatty acid content rated into an anti-aging cream with Matrixy1R which is a US 2014/0356295 A1 Dec. 4, 2014

brand of an anti-wrinkle active ingredient. The tobacco seed replaces caprylic/capric triglyceride in the product composi oil replaces caprylic/capric triglyceride in the product com tion. The resulting product has sensory characteristics similar position. The resulting product has sensory characteristics to the characteristics of a comparable composition containing similar to the characteristics of a comparable composition the replaced ingredient. containing the replaced ingredient. TABLE 4 TABLE 2 Green Apple Eye Serum Anti-Aging Cream ngredient Name Weight% ngredient Name Weight % Deionized Water 20-80 Deionized Water 2O-8O Tobacco Seed Oil -S Tobacco Seed Oil -S Glycerin -S Witch Hazel Extract -S Aloe Barbadensis Leaf Juice -S Glycerol Stearate -S Phenoxyethanol -S PEG-1 OO Stearate -S Acetyl Tetrapeptide-5 -S Glycerin -S Hesperidin Methylchalcone -S Butylene Glycol -S Steareth-20-Dipeptide-2 -S Carbomer -S Palmitoyl Tetrapeptide-7 -S Polysorbate 20 -S Carbomer -S Palmitoyl Pentapeptide-4 (Matrixyl (R) -S Fragrance -S Shea Butter -S Lecithin -S Glyceryl Polymethacrylate -S Alcohol -S PEG 8 Oligopeptide -S Lipoic Acid -S Phenoxyethanol -S Tocopheryl Acetate -S Caprylyl Glycol -S Potassium Sorbate -S Sorbic Acid -S Coenzyme Q10 -S Ammonium Acryloyldimethyltaurate VP Copolymer -S Sodium Hydroxide -S Cetearyl Olivate -S Retinyl Palmitate -S Sorbitan Olivate -S Cholecalciferol -S PPG-12 -S SMDI/Copolymer -S Sodium Hyaluronate -S Tocopheryl Acetate -5 Example 7 Disodium EDTA -S Xanthan Gum -S 0.115. As shown in Table 5, tobacco seed oil is incorpo Peppermint Oil -S rated into a facial cleansing cream composition. The tobacco Green Tea Extract -S seed oil replaces caprylic/capric triglyceride in the product Tetrahexyldecyl Ascorbate -S composition. The resulting product has sensory characteris tics similar to the characteristics of a comparable composition Example 5 containing the replaced ingredient. 0113. As shown in Table 3, tobacco seed oil is incorpo TABLE 5 rated into a facial and body cream composition. The tobacco seed oil replaces caprylic/capric triglyceride in the product Cleansing Cream composition. The resulting product has sensory characteris Ingredient Name Weight% tics similar to the characteristics of a comparable composition containing the replaced ingredient. Deionized Water 20-80 Tobacco Seed Oil -S Sodium C14-16 Olefin Sulfonate -S TABLE 3 Cocamidopropyl Betaine -S Glycerin -S Head to Toe Face and Body Crean Witch Hazel Extract -S Lauramide Diethanolamide -S Ingredient Name Weight% Glyceryl Stearate -S Polysorbate 60 -S Deionized Water 20-80 Stearic Acid -S Tobacco Seed Oil 1-5 Cetyl Alcohol -S Polyacrylamide 1-5 Shea Butter -S C 13-14 Isoparaffin 1-5 Phenoxyethanol -S Laureth-7 1-5 Caprylyl Glycol -S Glycerin 1-5 Sorbic Acid -S Aloe Barbadensis Leaf Juice 1-5 Sodium Hydroxymethylglycinate -S Isodecyl Neopentanoate 1-5 Carbomer -S Phenoxyethanol 1-5 Potassium Sorbate -S Potassium Sorbate 1-5 Tocopheryl Acetate 1-5 Fragrance O-2 Example 8 0116. As shown in Table 6, tobacco seed oil is incorpo Example 6 rated into a body butter composition. The tobacco seed oil 0114. As shown in Table 4, tobacco seed oil is incorpo replace Sunflower seed oil, almond oil, avocado oil and pump rated into an eye serum composition. The tobacco seed oil kin seed oil in the product composition. The resulting product US 2014/0356295 A1 Dec. 4, 2014

has sensory characteristics similar to the characteristics of a 2. The cosmetic composition of claim 1, wherein the comparable composition containing the replaced ingredients. extract is a tobacco seed oil. 3. The cosmetic composition of claim 2, wherein the TABLE 6 tobacco seed oil has a free fatty acid content of less than about Pomegranate and Acai Body Butter 15 weight percent, based on the total weight of the tobacco seed oil. Ingredient Name Weight% 4. The cosmetic composition of claim 2, wherein the Deionized Water 20-80 tobacco seed oil has a free fatty acid content of less than about Tobacco Seed Oil -S 10 weight percent, based on the total weight of the tobacco Cetearyl Alcohol -S Shea Butter -S seed oil. Glycerin -S Aloe Barbadensis Leaf Juice -S 5. The cosmetic composition of claim 2, wherein the Stearic Acid -S tobacco seed oil comprises at least about 60 weight percent of Phenoxyethanol -S linoleic acid, based on the total weight of the tobacco seed oil. Caprylyl Glycol -S Sorbic Acid -S 6. The cosmetic composition of claim 2, wherein the cos Cetyl Alcohol -S metic composition is in the form of an emulsion with an Carbomer -S aqueous phase and an oily phase comprising the tobacco seed Pomegranate (Punica Gradatum) Extract -S oil. Fragrance -S Panthenol -S 7. The cosmetic composition of claim 1, wherein the cos Tocopheryl Acetate -S metically acceptable carrier is an aqueous carrier and the Retinyl Palmitate -S Cholecalciferol -S composition is in the form of an emulsion. 8. The cosmetic composition of claim 1, wherein the cos metic composition is in the form of a liquid, a lotion, a gel, a Example 9 cream, a milk, an ointment, a paste, a plaster, a powder, a foam, a make-up, a stick, an aerosol, or embedded or 0117. As shown in Table 7, tobacco seed oil is incorpo absorbed in a wipe. rated into a hair cleansing composition. The tobacco seed oil 9. The cosmetic composition of claim 1, wherein the cos replaces caprylic/capric triglyceride in the product composi metic composition is adapted for use as a body moisturizing tion. The resulting product has sensory characteristics similar oil, a body moisturizing lotion, a body moisturizing gel, a to the characteristics of a comparable composition containing body moisturizing cream, a shaving preparation, a skin pow the replaced ingredient. der, a Suntan lotion, an anti-acne preparation, a peeling prepa ration, a shampoo, a hair conditioners, a hair tonic, a hair TABLE 7 styling cream, a hair styling gel, a pomade, a hair rinse, a Shampoo hair-straightening preparation, a hair-setting preparation, a hairspray, a hair dying or bleaching preparation, or a makeup. Ingredient Name Weight% 10. The cosmetic composition of claim 1, wherein the Deionized Water 20-80 cosmetic composition further comprises one or more cos Sodium Lauryl Sulfate 25-35 Cocamideopropyl Betaine 10-2S metic adjuvants selected from the group consisting of addi Sodium Laureth Sulfate 1-10 tional fats or lipids, organic solvents, thickeners, binders, Tobacco Seed Oil 1-10 conditioning agents, demulcents, opacifiers, stabilizers, buff Ammonium Chloride 1-5 ering agents, humectants, pigments, dyes, viscosity modifi Citric Acid O-5 EDTA O-5 ers, emollients, antiperspirants, anti-foaming agents, foam Sodium Chloride O-5 boosters, hair colorants, hair penning agents, hair growth or Fragrance O-5 restorer agents, hair loss prevention agents, abrasives, absor Polysorbate 20 O-5 bents, anti-acne agents, anti-caking agents, moisturizing DMDM Hydantoin O-5 agents, perfumes or fragrances, preservatives, Sunscreens, astringents, propellants, bleaching or lightening agents for 0118 Many modifications and other embodiments of the skin or hair, tanning agents, deposition aids, Suspending invention will come to mind to one skilled in the art to which agents, polymers, fillers, sequestrants, bactericides, odor this invention pertains having the benefit of the teachings absorbers, antifungal agents, alkalinizing or acidifying presented in the foregoing description. Therefore, it is to be agents, pearlescent aids, chelants, proteins, anti-dandruff understood that the invention is not to be limited to the spe agents, Surfactants, emulsifiers, anti-free radical agents, anti cific embodiments disclosed and that modifications and other oxidants, vitamins, and C-hydroxy acids. embodiments are intended to be included within the scope of 11. The cosmetic composition of claim 1, wherein the the appended claims. Although specific terms are employed cosmetically acceptable carrier comprises water and the cos herein, they are used in a generic and descriptive sense only metic composition is in the form of a lotion or cream emulsion and not for purposes of limitation. with an aqueous phase and an oily phase comprising a What is claimed: tobacco seed oil, the cosmetic composition further compris 1. A cosmetic composition comprising an extract of a seed ing one or more cosmetic adjuvants selected from the group of the Nicotiana species and at least one cosmetically accept consisting of additional oils, thickeners, Surfactants, preser able carrier, wherein the cosmetic composition is in a form Vatives, pigments, humectants, emollients, occlusives, and adapted for application to skin or hair. combinations thereof. US 2014/0356295 A1 Dec. 4, 2014

12. The cosmetic composition of claim 1, wherein the 20. The cosmetic composition of claim 1, wherein the cosmetic composition further comprises one or more emol cosmetic composition further comprises one or more natural lients in an amount of about 0.01 to about 20% by weight of or essential oils in an amount of about 0.01 to about 20% by the cosmetic composition. weight of the cosmetic composition. 13. The cosmetic composition of claim 1, wherein the cosmetic composition further comprises one or more humec 21. The cosmetic composition of claim 1, wherein the tants in an amount of about 0.01 to about 10% by weight of the cosmetic composition further comprises one or more occlu cosmetic composition. sives in an amount of about 0.01 to about 5% by weight of the 14. The cosmetic composition of claim 1, wherein the cosmetic composition. cosmetic composition further comprises one or more Surfac tants in an amount of about 0.01 to about 50% by weight of the 22. The cosmetic composition of claim 1, wherein the cosmetic composition. cosmetic composition further comprises one or more agents 15. The cosmetic composition of claim 1, wherein the useful for treating wrinkles in the skin in an amount of about cosmetic composition further comprises one or more condi 0.01 to about 5% by weight of the cosmetic composition. tioning agents in an amount of about 0.01 to about 5% by 23. The cosmetic composition of claim 1, wherein the weight of the cosmetic composition. cosmetic composition is in the foam of an emulsion adapted 16. The cosmetic composition of claim 1, wherein the for moisturizing skin, the cosmetic composition comprising cosmetic composition further comprises one or more preser water in an amount up to about 80% by weight, a tobacco seed vatives in an amount of about 0.01 to about 10% by weight of oil in an amount up to about 10% by weight, one or more the cosmetic composition. emollients in an amount up to about 20% by weight, one or 17. The cosmetic composition of claim 1, wherein the more emulsifiers in an amount up to about 15% by weight, cosmetic composition further comprises one or more thick and one or more humectants in an amount up to about 10% by ening agents in an amount of about 0.01 to about 15% by weight. weight of the cosmetic composition. 18. The cosmetic composition of claim 1, wherein the 24. The cosmetic composition of claim 1, wherein the cosmetic composition further comprises one or more emul cosmetic composition is in the form of an emulsion adapted sifiers in an amount of about 0.01 to about 15% by weight of for cleansing skin or hair, the cosmetic composition compris the cosmetic composition. ing water in an amount up to about 80% by weight, a tobacco 19. The cosmetic composition of claim 1, wherein the seed oil in an amount up to about 10% by weight, one or more cosmetic composition further comprises one or more antioxi emulsifiers in an amount up to about 15% by weight, and one dants in an amount of about 0.01 to about 10% by weight of or more surfactants in an amount up to about 50% by weight. the cosmetic composition. k k k k k