DOCSLIB.ORG

(12) United States Patent (10) Patent No.: US 6,420,181 B1 Novak (45) Date of Patent: *Jul

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
(12) United States Patent (10) Patent No.: US 6,420,181 B1 Novak (45) Date of Patent: *Jul USOO642O181B1 (12) United States Patent (10) Patent No.: US 6,420,181 B1 Novak (45) Date of Patent: *Jul. 16, 2002 (54) FIELD MICROSPOT TEST METHOD FOR (56) References Cited ON-SITE CHEMICAL TESTING U.S. PATENT DOCUMENTS (75) Inventor: Thaddeus John Novak, Bel Air, MD (US) 4,346,001 A * 8/1982 Tyihak et al. ............... 210/658 4,428,908 A * 1/1984 Ashley et al. ................ 422/61 (73) Assignee: The United States of America as represented by the Secretary of the Army, Washington, DC (US) sk cited- by examiner (*) Notice: Subject to any disclaimer, the term of this Primary Examiner-Lyle A. Alexander patent is extended or adjusted under 35 XX U.S.C. 154(b) by 0 days (74) Attorney, Agent, or Firm Ulysses John Biffoni; a -- William W. Randolph Rpatent is Subject to a terminal dis- (57) ABSTRACT A method, System and kit for detecting the presence of an (21) Appl. No.: 09/296,602 analyte includes placing a Solution containing the analyte in 1-1. a microcapillary tube and placing the microcapillary tube in (22) Filed: Apr. 23, 1999 contact with a layer of Sorbent material So that the Solution Related U.S. Application Data is withdrawn from the microcapillary tube by capillary action. The Sorbent material and Solvent for the Solution are (63) Continuation-in-part of application No. 08/763,181, filed on Selected so that the Solvent is absorbed into the Sorbent Dec. 11, 1996, now Pat. No. 5,935,862. material and the analyte is adsorbed by the Sorbent material (51) Int. Cl." ......................... G01N33/00, G01N 30/90 and concentrated at the Spot where the microcapillary tube (52) U.S. Cl. ....................... 436/104; 436/162; 436/164: contacts the Sorbent material. A detector reagent is applied 436/66. 436/165. 210,658 to the Sorbent material to indicate the presence of the (58) Field of Search ................................. 210/656, 658, analyte. 210/634, 635; 422/56, 58, 61, 68.1, 70; 436/103-105,161-164, 166, 169, 808 16 Claims, 2 Drawing Sheets U.S. Patent Jul. 16, 2002 Sheet 1 of 2 US 6,420,181 B1 A/G. f. 27 U.S. Patent Jul. 16, 2002 Sheet 2 of 2 US 6,420,181 B1 A/G. 4 NEGATIVE TEST POST VETEST US 6,420,181 B1 1 2 FIELD MICROSPOT TEST METHOD FOR having a Surface layer formed of a Sorbent material or gel. ON-SITE CHEMICAL TESTING In order to Separate the components of the analyte obtained from a Sample, a drop of Solution is carefully applied above This is a Continuation-In-Part of U.S. application Ser. the bottom edge of a thin layer chromatography plate. No. 08/763,181, filed Dec. 11, 1996 now U.S. Pat. No. 5 Solutions Suspected of containing target analytes are pref 5,935,862. erably deposited onto the surface of a TLC plate in the form of a drop to avoid a streaking pattern that would result if the GOVERNMENT INTEREST device for applying the drop actually contacts the Surface of the plate while a Sample Solution is being deposited. After The invention described herein may be manufactured, the Solvent evaporates, the residue on the plate is eluted with licensed, and used by or for the U.S. Government. another Solvent or Solvent mixture (also known as the eluant) thereby causing the chemical components of the BACKGROUND OF THE INVENTION Sample to migrate towards the top or opposite edge of the 1. Field of the Invention plate. When the proper conditions and eluant are chosen, This invention relates to a field test kit and method of 15 each analyte migrates across the plate at a rate that is on-site testing for the presence of contaminants and different from the other analytes. The elution step results in chemicals, and more particularly to a micro spot method for the different analytes Separating from each other and Settling detecting the presence of a variety of chemicals and envi at different regions and as diffuse spots along the path of ronmental contaminants. migration. After the elution Step, the plates are allowed to dry and then they are Sprayed with a Solution of visualization 2. Description of the Prior Art reagent (detector reagent). A persistent concern with thin In View of biological hazards associated with toxic chemi layer chromatography is that the elution Step of waiting for cals and environmental contaminants, regulations have been the Solvent to completely wet the plate and for the analytes established by legislatures and environmental agencies to to migrate and Separate is relatively time-consuming. In monitor a wide variety of chemicals and their byproducts. AS 25 many instances, proper completion of the elution phase may a result, it is often necessary to conduct on-site inspections exceed an hour and warrant involved techniques and quality and analyses of various chemical Spills, dump Sites, and control Steps to assure adequate Separation of the different manufacturing facilities to detect environmental analytes. Another concern involves situations where the contaminants, hazardous conditions and to assure compli analytes are present in Such low concentrations that the ance with environmental regulations. detection Signals obtained in the tests are weak and can Advantages of on-site inspection and analysis of chemical possibly be misread. In Summary, with thin layer chroma Sites include resolving ambiguities during the inspection, tography the analytes in the Sample migrate and Separate reducing the potential for contamination and croSS into localized regions, as opposed to concentrated at Spots or contamination of Samples during travel to off-site testing points. laboratories, and providing a convenient method of perform 35 ing a large number of preliminary tests to detect and Screen SUMMARY OF THE INVENTION for chemical contaminants. On-site inspection also provides The micro Spot test System and methodology of the a rapid indication of those Samples which may possibly present invention relates to an apparatus and method for the contain compounds that must be identified using more on-site testing of analytes contained in a Sample by dissolv Sophisticated laboratory analytical techniques. On-site test 40 ing the analytes in a Solvent and utilizing capillary deposi ing also allows the level of concentration and Spread of tion techniques to concentrate the analytes on Sorbent mate contamination from chemical Spills to be readily Surmised. rials. Detection Sensitivity and accuracy for a range of Reagent-based chemical detection and chromatographic concentrations of analytes is provided by applying a Solution methodologies are attractive for on-site testing and Screen containing the analytes to a Sorbent layer by capillary ing because many tests can be run in a short period of time 45 deposition So that the analytes in the Solution become and they are capable of providing Visual presumptive evi concentrated at the particular spot or point of deposition on dence of the presence of a chemical Substance in a Sample. the Sorbent layer. The Solutions are deposited by placing One methodology comprises classical Spot tests that are Small diameter tubes containing the analyte Solution in normally carried out in depressions or wells of a porcelain contact with the Surface of the Sorbent material So that the Spot plate. Conventionally, Small amounts of a Solution, 50 solutions are drawn from the small diameter tubes by which may contain chemical contaminants, are placed in the capillary action. A detector reagent is then utilized to detect Wells of the Spot plate. Small quantities of different reagents the presence of the analytes that are concentrated at the Spot are then added to the Solution Samples and a positive test is where the Small diameter tube contacts the Sorbent layer. normally signified by a color change in the well of the Spot A System for chromogenically detecting the presence of plate. An advantage with these tests is that a number of tests 55 chemical analytes includes a means for obtaining a Sample can be carried out on a single plate. For example, as many Solution containing the analytes, a device for the capillary as 12 different Spot tests can be carried out on a Small deposition of the Sample Solution, chromatographic Sorbent 3.5x4.5 inch spot plate. Another advantage is that it is materials, and chromogenic detector reagents. Storage possible to rapidly Screen a large number of Samples during devices may be provided for the Samples and for Sample a short period of time. However, as the concentration of the 60 Solutions, capillary deposition devices, the chromatographic chemical Substances become more dilute, it becomes more Sorbent materials and the chromogenic detector reagents. difficult to reliably detect the presence of the chemical Accordingly, one object of the present invention is to Substances. In most cases, the lower limit of detection is in provide a compact chemical Screening apparatus which is of the 1-100 microgram range. a Self-contained, efficient design for rapid Screening of Another methodology for Screening Samples and detect 65 Solutions for the presence or absence of target analytes. ing target analytes in Samples is use of thin layer chroma Another object of the present invention is to provide a tography (or TLC), which conventionally utilizes a plate chemical Screening device which is relatively simple to use US 6,420,181 B1 3 4 for Sample Solutions containing a wide range of analytes in Washing, extracting, or eluting a Sample with a Solvent or a wide range of concentration levels. mixture of solvents. For example, surface wipes 18 or Swabs These, together with still other objects of the invention, 19 of polyester or similar material are used to obtain a along with the various features which characterize the Sample by wiping a Suspected Surface.
Load more

Recommended publications
  • Characterization of Strychnine Binding Sites in the Rodent
    CHARACTERIZATION OF STRYCHNINE BINDING SITES IN THE RODENT SPINAL CORD BY VINCENT MAURICE O’CONNOR UNIVERSITY COLLEGE LONDON A thesis submitted for the degree of Doctor of Philosophy from the University of London, 1992. I ProQuest Number: 10608898 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a com plete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest ProQuest 10608898 Published by ProQuest LLC(2017). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States C ode Microform Edition © ProQuest LLC. ProQuest LLC. 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106- 1346 This thesis is dedicated to the select band o f people, including the most recent arrivals and the sorely missed departed, that I hold closest in my affections. "At the end of the day" they make It all worthwhile. Remember, in the words of the famous actor whose name at present escapes me; "Nobody said it would be easy". Although my own feeling is that Nobody was probably wrong. II Thesis abstract The convulsant alkaloid strychnine is a selective and highly potent antagonist at postsynaptic receptor for the inhibitory neurotransmitter glycine . These properties have led to the extensive use of strychnine as a ligand to probe the postsynaptic glycine receptor. Despite the recent increased understanding of the molecular structure of this receptor protein there is still much dispute as to the nature of the interaction between glycine and strychnine.
    [Show full text]
  • Chemistry Inventory; Fall
    CHEMISTRY FALL 2005 MSDS Mfg.'s Name Chemical Name Quantity Stored Storage Conditions (on file = 9) Aluminum 9 1.5 kg Aluminum chloride, anhydrous, 98.5% 9 0.2 kg Aluminum chloride · 6H2O 9 0.5 kg Aluminum hydroxide 9 0.5 kg Aluminum nitrate 9 0.5 kg Aluminum sulfate 9 0.5 kg Ammonia, concentrated 9 4.0 L Ammonium acetate 9 0.2 kg Ammonium chloride 9 Ammonium dihydrogen phosphate (monobasic) 9 0.4 kg J.T. Baker Ammonium hydrogen phosphate (dibasic) No 0.5 kg Ammonium nitrate 9 2.5 kg Ammonium oxalate 9 0.7 kg Ammonium peroxydisulfate 9 0.5 kg Ammonium sulfate 9 0.2 kg Antimony 9 0.4 kg Barium chloride, anhydrous 9 2.5 kg Barium chloride · 2H2O 9 2.5 kg Barium nitrate 9 0.8 kg Bismuth 9 2.0 kg Boric Acid 9 0.4 kg Brass 9 Bromine 9 2.5 kg Cadmium 9 0.1 kg Cadmium nitrate 9 0.3 kg Calcium acetate · xH2O 9 0.5 kg Calcium carbide 9 1.0 kg Calcium carbonate 9 2.2 kg Calcium chloride 9 1.0 kg Calcium hydroxide 9 0.3 kg Calcium nitrate · 4H2O 9 1.0 kg Calcium oxide 9 0.3 kg Calcium sulfate · 2H2O 9 1.0 kg Carbon 9 0.1 kg Ceric ammonium nitrate 9 0.5 kg Cesium chloride 9 0.01 kg Chromium 9 0.01 kg Chromium chloride 9 0.5 kg Chromium nitrate 9 0.5 kg Cobalt 9 0.025 kg Cobalt chloride 9 0.7 kg Cobalt nitrate 9 0.6 kg Copper (assorted) 9 4.0 kg Copper acetate 9 0.05 kg Copper chloride 9 0.1 kg Copper nitrate 9 3.5 kg Copper oxide 9 0.4 kg Cupric sulfate, anhydrous 9 0.5 kg Cupric sulfate · 5H2O 9 2.75 kg EDTA 9 0.6 kg Iodine 9 2.0 kg Iron (assorted) 9 5.0 kg MSDS Mfg.'s Name Chemical Name Quantity Stored Storage Conditions (on file = 9) Ferric ammonium
    [Show full text]
  • Chemical Resistance of Plastics
    (c) Bürkle GmbH 2010 Important Important information The tables “Chemical resistance of plastics”, “Plastics and their properties” and “Viscosity of liquids" as well as the information about chemical resistance given in the particular product descriptions have been drawn up based on information provided by various raw material manufacturers. These values are based solely on laboratory tests with raw materials. Plastic components produced from these raw materials are frequently subject to influences that cannot be recognized in laboratory tests (temperature, pressure, material stress, effects of chemicals, construction features, etc.). For this reason the values given are only to be regarded as being guidelines. In critical cases it is essential that a test is carried out first. No legal claims can be derived from this information; nor do we accept any liability for it. A knowledge of the chemical and mechanical Copyright This table has been published and updated by Bürkle GmbH, D-79415 Bad Bellingen as a work of reference. This Copyright clause must not be removed. The table may be freely passed on and copied, provided that Extensions, additions and translations If your own experiences with materials and media could be used to extend this table then we would be pleased to receive any additional information. Please send an E-Mail to [email protected]. We would also like to receive translations into other languages. Please visit our website at http://www.buerkle.de from time to Thanks Our special thanks to Franz Kass ([email protected]), who has completed and extended these lists with great enthusiasm and his excellent specialist knowledge.
    [Show full text]
  • Loba Chemie Pvt
    TABLE OF CONTENT INTRODUCTION Contact US ii MD Letter iii Company Profile iv Latest Information v Label vi Certifications vii GMP Compliant Pharma Facility viii QC Capability ix R&D x Logistic xi COA xii SDS xiii Packing xiv Quality xvi Terms Of Sales xvii Application xviii Product Highlights xix Nanopowder & Carbon Nanotubes xxvii List of New Products xxviii ALPHABETICAL PRODUCT LISTING Price List Chemical 01-155 Ecosafe Safety Products 156-160 Macherey-Nagel Filtration Products 161-181 [email protected] I CONTACT US Contact us for more information on any of our products and services HEAD OFFICE - MUMBAI Loba Chemie Pvt. Ltd., Jehangir Villa, 107, Wode House Road, Colaba, Mumbai-400005 Maharashtra, India Tel: +91(022) 6663 6663 Fax: +91(022) 6663 6699 MANUFACTURING UNIT (TARAPUR) Loba Chemie Pvt. Ltd., Plot No.: D-22, M.I.D.C. Tarapur, Boisar, Taluka: Palghar, Thane-401506 Maharashtra, India Ph: +91(02525) 300 001 Stay up to date about our range and availability www.lobachemie.com Get in touch with us General Enquiry: [email protected] Technical Query: [email protected] Domestic Sales: [email protected] Export Sales: [email protected] Follow us on: ii www.lobachemie.com WELCOME AT LOBA CHEMIE Dear Valued Reader Another exciting year has gone by and we would like to start the New Year, as usual, with a new catalogue featuring more innova- tive highest quality range of routine and novel Laboratory Chemi- cal and Fine Reagents. With our more than 4 decads of expertise in Laboratory Chemical and Fine Reagents we not only bring you a complete Laboratory at your fingertips but in addition with our expertise we have palced our brand of products in a very competitive position for years to come.
    [Show full text]
  • |||||III USOO5547541A United States Patent (19) 11) Patent Number: 5,547,541 Hansen Et Al
    |||||III USOO5547541A United States Patent (19) 11) Patent Number: 5,547,541 Hansen et al. 45) Date of Patent: Aug. 20, 1996 54) METHOD FOR DENSEFYING FIBERS USING OTHER PUBLICATIONS A DENSIFYINGAGENT Gugliemelli et al., "Base-Hydrolyzed Starch-Polyacryloni (75) Inventors: Michael R. Hansen, Seattle; Richard trile (S-PAN) Graft Copolymer. S-PAN-1:1, PAN. M. W. H. Young, Sr., Renton, both of Wash. 794,000*", J. of Applied Copolymer Science, 13:2007-2017 (1969). (73) Assignee: Weyerhaeuser Company, Federal Way, Weaver et al., "Hydrolyzed Starch-Polyacrylonitrile Graft Wash. Copolymers: Effect of Structure on Properties', J. of Applied Polymer Science, 15:3015–3024 (1971). Weaver et al., "Highly Absorbent Starch-Based Polymer." 21 Appl. No.: 197483 Northern Regional Research Laboratory, Agricultural 22) Filed: Feb. 16, 1994 Research Service, U.S. Dept. of Agriculture, Peoria, Illinois, pp. 169-177. Related U.S. Application Data "Super slurpers: Time for change?,” Chemical Week, pp. 21-22 (Jul. 24, 1974). (63) Continuation-in-part of Ser. No. 931,059, Aug. 17, 1992, S. Lammie, "Use of Glycerine as a Softener for Paper Ser. No. 931,277, Aug. 17, 1992, Ser. No. 931,213, Aug. 17, 1992, Pat. No. 5,300,192, Ser. No. 931,278, Aug. 17, 1992, Products." The World's Paper Trade Review, Dec. 13, 1962, Pat. No. 5,352,480, Ser. No. 931,284, Aug. 17, 1992, Pat. p. 2050. No. 5,308,896, Ser. No. 931,279, Aug. 17, 1992, Ser. No. Lindsay, "Absorbent Starch Based Co-polymers- Their 107,469, Aug. 17, 1993, Ser. No. 108,219, Aug.
    [Show full text]
  • Lab & Reagent Chemicals Pat Impex
    LAB CHEMICALS & REAGENTS – FINE CHEMICALS Manufacturer, Suppliers & Distributor MANUFACTURER SUPPLIER AND DISTRIBUTOR OF LABORATORY CHEMICALS, FINE CHEMICALS, AR LR GRADE, SUPERFINE CHEMICALS IN VADODARA, GUJARAT, INDIA. Our Introduction LAB CHEMICALS, REAGENTS GRADE CHEMICALS, BULK PACKING Our Range of Products • Laboratory chemicals & Reagents • Fine Chemicals AR LR ACS PH EUR • General Chemicals by Trading • Nanotechnology chemicals LABORATORY CHEMICALS, REAGENTS, FINE CHEMICALS • Acetamide Pure • Acetanilide Extrapure • Adipic Acid Pure • Acetanilide Exiplus • Aerosil 200 (Fumed Silica Gel) • Acetic Acid Glacial Extrapure • Agar Powder Regular Grade • Acetic Acid Glacial Extrapure Ar • Agar Powder Exiplus • Acetic Acid Glacial Extrapure Ar,acs,exiplus • Agar Powder Extrapure Bacto Grade • Acetic Acid Dried • Agar Granulated Bacto Grade • Acetic Acid For Hplc • Ajowan Seed Oil Extrapure • Acetic Acid Glacial For Molecular Biology • L-alanine Extrapure Chr • Acetone Pure • Aliquat 336 • Acetone Extrapure Ar • Alloxan Monohydrate • Acetone Extrapure Ar,acs,exiplus • Allyl Alcohol Pure • Acetone Gc-hs • Allylamine Pure • Acetone For Hplc & Uv Spectroscopy • Allyl Bromide Pure • Acetone For Uv Spectroscopy • Almond Oil Pure • Acetone Electronic Grade • Aluminium Ammonium Sulphate Dodecahydrate Pure • Acetone For Molecular Biology • Aluminium Ammonium Sulphate Dodecahydrate Extrapure Ar • Acetone -d6 For Nmr Spectroscopy • Aliminium Atomic Absorption Std.soln.aas • Acetonitrile(Acn)extrapure • Aluminium Metal Powder • Acetonitrile(Acn)extrapure
    [Show full text]
  • Chemical Compatibility Storage Group
    CHEMICAL SEGREGATION Chemicals are to be segregated into 11 different categories depending on the compatibility of that chemical with other chemicals The Storage Groups are as follows: Group A – Compatible Organic Acids Group B – Compatible Pyrophoric & Water Reactive Materials Group C – Compatible Inorganic Bases Group D – Compatible Organic Acids Group E – Compatible Oxidizers including Peroxides Group F– Compatible Inorganic Acids not including Oxidizers or Combustible Group G – Not Intrinsically Reactive or Flammable or Combustible Group J* – Poison Compressed Gases Group K* – Compatible Explosive or other highly Unstable Material Group L – Non-Reactive Flammable and Combustible, including solvents Group X* – Incompatible with ALL other storage groups The following is a list of chemicals and their compatibility storage codes. This is not a complete list of chemicals, but is provided to give examples of each storage group: Storage Group A 94‐75‐7 2,4‐D (2,4‐Dichlorophenoxyacetic acid) 94‐82‐6 2,4‐DB 609-99-4 3,5-Dinitrosalicylic acid 64‐19‐7 Acetic acid (Flammable liquid @ 102°F avoid alcohols, Amines, ox agents see SDS) 631-61-8 Acetic acid, Ammonium salt (Ammonium acetate) 108-24-7 Acetic anhydride (Flammable liquid @102°F avoid alcohols see SDS) 79‐10‐7 Acrylic acid Peroxide Former 65‐85‐0 Benzoic acid 98‐07‐7 Benzotrichloride 98‐88‐4 Benzoyl chloride 107-92-6 Butyric Acid 115‐28‐6 Chlorendic acid 79‐11‐8 Chloroacetic acid 627‐11‐2 Chloroethyl chloroformate 77‐92‐9 Citric acid 5949-29-1 Citric acid monohydrate 57-00-1 Creatine 20624-25-3
    [Show full text]
  • Spectra Library Index Ichem/SDBS Raman Library
    Ichem / SDBS Raman スタンダードライブラリー 株式会社 エス・ティ・ジャパン S p e c t r a L i b r a r y I n d e x (Ver. 40) Ichem / SDBS Raman Library ライブラリー名：ラマンスタンダードライブラリー 商品番号：60001-40 株式会社 エス・ティ・ジャパン 〒103-0014 東京都中央区日本橋蛎殻町 1-14-10 Tel: 03-3666-2561 Fax:03-3666-2658 http://www.stjapan.co.jp 1 【販売代理店】（株）テクノサイエンス Tel：043-206-0155 Fax：043-206-0188 https://www.techno-lab-co.jp/ Ichem / SDBS Raman スタンダードライブラリー 株式会社 エス・ティ・ジャパン ((1,2-DIETHYLETHYLENE)BIS(P-PHENYLENE))DIACETATE ((2-(3-BENZYLSULFONYL-4-METHYLCYCLOHEXYL)PROPYL)SULFONYLMETHYL)BENZENE ((2,4,6-TRIOXOHEXAHYDRO-5-PYRIMIDINYL)IMINO)DIACETIC ACID ((2-CARBOXYETHYL)IMINO)DIACETIC ACID ((2-HYDROXYETHYL)IMINO)DIACETIC ACID ((2-NITROBENZYL)IMINO)DIACETIC ACID ((2-SULFOETHYL)IMINO)DIACETIC ACID ((3-(1-BROMO-1-METHYLETHYL)-7-OXO-1,3,5-CYCLOHEPTATRIEN-1-YL)OXY)DIFLUOROBORANE ((N-BENZYLOXYCARBONYL-L-ISOLEUCYL)-L-PROLYL-L-PHENYLALANYL)-N(OMEGA)-NITRO-L-ARGININE 4-NITROBENZYL ESTER (-)-2-AMINO-1-BUTANOL (-)-2-AMINO-6-MERCAPTOPURINE RIBOSIDE (-)-6,8-P-MENTHADIEN-2-OL (-)-DIACETYL-L-TARTARIC ACID (-)-DIBENZOYL-L-TARTARIC ACID (-)-DI-P-ANISOYL-L-TARTARIC ACID (-)-DI-P-TOLUOYL-L-TARTARIC ACID (-)-KAURENE (-)-MENTHOL (-)-MYRTENOL (-)-N,N,N',N'-TETRAMETHYL-D-TARTARDIAMIDE (-)-N,N'-DIBENZYL-D-TARTRAMIDE (+)-1,3,3-TRIMETHYLNORBORNANE-2-ONE (+)-2-(2,4,5,7-TETRANITRO-9-FLUORENYLIDENEAMINOOXY)PROPIONIC ACID (+)-2-AMINO-1-BUTANOL (+)-2-PINENE (+)-3,9-DIBROMOCAMPHOR (+)-3-CARENE (+)-5-BROMO-2'-DEOXYURIDINE (+)-AMMONIUM 3-BROMO-8-CAMPHORSULFONATE (+)-CAMPHOR (+)-CAMPHOR OXIME (+)-CAMPHORIC ACID (+)-CATECHIN (+)-DI-P-ANISOYL-D-TARTARIC
    [Show full text]
  • Decomposition of Coal with Periodic Acid Plus Perchloric Acid for the Isolation of Spores and for the Determination of Minor Components Gerald I
    Iowa State University Capstones, Theses and Retrospective Theses and Dissertations Dissertations 1963 Decomposition of coal with periodic acid plus perchloric acid for the isolation of spores and for the determination of minor components Gerald I. Spielholtz Iowa State University Follow this and additional works at: https://lib.dr.iastate.edu/rtd Part of the Analytical Chemistry Commons, and the Oil, Gas, and Energy Commons Recommended Citation Spielholtz, Gerald I., "Decomposition of coal with periodic acid plus perchloric acid for the isolation of spores and for the determination of minor components " (1963). Retrospective Theses and Dissertations. 2499. https://lib.dr.iastate.edu/rtd/2499 This Dissertation is brought to you for free and open access by the Iowa State University Capstones, Theses and Dissertations at Iowa State University Digital Repository. It has been accepted for inclusion in Retrospective Theses and Dissertations by an authorized administrator of Iowa State University Digital Repository. For more information, please contact [email protected]. This dissertation has been 63—7276 microfilmed exactly as received SPIELHOLTZ, Gerald I., 1937- DECOMPOSITION OF COAL WITH PERIODIC ACID PLUS PERCHLORIC ACID FOR THE ISOLATION OF SPORES AND FOR THE DETERMINATION OF MINOR COMPONENTS. Iowa State University of Science and Technology Ph.D„ 1963 Chemistry, analytical University Microfilms, Inc., Ann Arbor, Michigan DECOMPOSITION OF COAL WITH PERIODIC ACID PLUS PERCHLORIC ACID FOR THE ISOLATION OF SPORES AND FOR THE DETERMINATION OF MINOR COMPONENTS by Gerald I. Spielholtz A Dissertation Submitted to the Graduate Faculty in Partial Fulfillment of The Requirements for the Degree of DOCTOR OF PHILOSOPHY Major Subject: Analytical Chemistry Approved: Signature was redacted for privacy.
    [Show full text]
  • Analytical Chemistry
    MINISTRY OF HEALTHCARE OF UKRAINE PIROGOV VINNYTSYA NATIONAL MEDICAL UNIVERSITY THE PHARMACEUTICAL CHEMISTRY CHAIR 250 200 150 100 Analytical chemistry 50 Part I Qualitative analysis Educational manual is prepared for foreign students of the pharmaceutical faculty dissolved components sample precipitating agent Vinnytsya 2012 MINISTRY OF HEALTHCARE OF UKRAINE PIROGOV VINNYTSYA NATIONAL MEDICAL UNIVERSITY THE PHARMACEUTICAL CHEMISTRY CHAIR Analytical chemistry Part I Qualitative analysis Educational manual is prepared for foreign students of the pharmaceutical faculty Vinnytsya 2012 «Approved» by Methodical council of Pirogov National Medical University of Vinnytsya Minutes №1 of 30.08.2012 Authors: T.I. Yuschenko N.I. Kaminska A.E. Kosareva L.V. Slobodyanyuk O.P. Yashchuk The educational manual to practical classes in analytical chemistry for foreign students of the pharmaceutical higher school and the pharmaceutical faculties of the III-IV levels of “Quantitative analysis” accreditation. 2 Introduction The analytical chemistry is one of the fundamental chemical disciplines, which is the basis for the subsequent study of such core of disciplines as pharmaceutical chemistry, pharmacognosicy, forensic chemistry, technology of drugs, etc. for future specialists in pharmacy. Analytical Chemistry is the science of the methods for studying the composition of material. It consists of two basic divisions: qualitative analysis (what is present) and quantitative analysis (how much is present). The aim of analytical chemistry teaching is creating the theoretical basis of chemical analysis for the students and also practical skills and experience of making it. The given manual for practical classes in analytical chemistry is intended for self-preparation of students for practical classes, carrying-out the experiment.
    [Show full text]
  • Aspects of the Radiation Chemistry and Protection of Peptides
    A S P E C T S 0 F T HE R A D I A T I O N C H E M I S T R Y A, N D P R O T E C T I O N O F P E P T I D E S A thesis submitted in partial fulfillment of the requirements for the degree of M A S T E R 0 F S C I E N C E in the University of New South Wales by J.A. HOURIGAN, B.Sc. July, 1971. (11) The work contained in this thesis has not been submitted for a degree or similar award to any other University or Institution. J.A. HOURIGAN (111) Aspects of the radiation chellliatry and protection of the polypeptide chain of catalase were investigated, employing the soluble enz,111le and also insoluble, poly(diazostyrene)-bound catalase. Prior investigation of the structure of the inaolubilized catalase by ion-exchange chromatography of its hydrolysate showed that approximately 140 residues (histidine, lysine, cysteine and tyrosine, i.e. roughly half the total number of these residues per catalase aolecule) were covalently linked to poly(diazostyrene) molecules. The conjugate was pictured as a catalase molecule to which a large number (20-100) of poly(diazostyrene) molecules were covalently linked. The results indicate further, and in agreement with the results of irradiation experiments, that the tyrosine and arginine residues are mainly located in the interior of the active conformer of the catalase molecule. A novel pyrolysis-gas chromatographic technique was developed for the estimation of the protein content of poly(diazostyrene)-bound catalase.
    [Show full text]
  • 2015 WHMIS Classification : List of English Names in Alphabetical Order
    CNESST - Répertoire toxicologique Workplace Hazardous Materials Information System 2015 WHMIS classification of chemical substances List of english names in alphabetical order The classification list provided in this document was compiled in response to requests for information concerning classifications under federal legislation on hazardous products. Please note that this is not an exhaustive list of hazardous products according to WHMIS 2015. This classification was established by CNESST personnel to the best of their knowledge based on data obtained from scientific literature and it incorporates the criteria contained in the Hazardous Products Regulations (SOR/2015-17). It does not replace the supplier's classification which can be found on its Safety Data Sheet. This list contains 2425 products names. You can press on the name of products to obtain their classification. You can press the name of any product in the list to obtain his WHMIS classification. All products Product's names CAS UN Acenaphthene 83-32-9 Acenaphthoquinone 82-86-0 Acenaphthylene 208-96-8 Acepromazine 61-00-7 Acetaldehyde 75-07-0 UN1089 Acetaldehyde diethylacetal 105-57-7 Acetamide 60-35-5 Acetaminophen 103-90-2 Acetanilide 103-84-4 Acetic acid 64-19-7 UN2789 Acetic acid, C6-C8 branched alkyl esters 90438-79-2 Acetic acid, more than 80% UN2789 Acetic anhydride 108-24-7 UN1715 Acetoacetanilide 102-01-2 o-Acetoacetaniside 92-15-9 Acetone 67-64-1 UN1090 2021-08-04 List of WHMIS controlled products 1 of 79 CNESST - Répertoire toxicologique Acetonitrile 75-05-8 UN1648
    [Show full text]