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Female Fellows of the Royal Society
Female Fellows of the Royal Society Professor Jan Anderson FRS [1996] Professor Ruth Lynden-Bell FRS [2006] Professor Judith Armitage FRS [2013] Dr Mary Lyon FRS [1973] Professor Frances Ashcroft FMedSci FRS [1999] Professor Georgina Mace CBE FRS [2002] Professor Gillian Bates FMedSci FRS [2007] Professor Trudy Mackay FRS [2006] Professor Jean Beggs CBE FRS [1998] Professor Enid MacRobbie FRS [1991] Dame Jocelyn Bell Burnell DBE FRS [2003] Dr Philippa Marrack FMedSci FRS [1997] Dame Valerie Beral DBE FMedSci FRS [2006] Professor Dusa McDuff FRS [1994] Dr Mariann Bienz FMedSci FRS [2003] Professor Angela McLean FRS [2009] Professor Elizabeth Blackburn AC FRS [1992] Professor Anne Mills FMedSci FRS [2013] Professor Andrea Brand FMedSci FRS [2010] Professor Brenda Milner CC FRS [1979] Professor Eleanor Burbidge FRS [1964] Dr Anne O'Garra FMedSci FRS [2008] Professor Eleanor Campbell FRS [2010] Dame Bridget Ogilvie AC DBE FMedSci FRS [2003] Professor Doreen Cantrell FMedSci FRS [2011] Baroness Onora O'Neill * CBE FBA FMedSci FRS [2007] Professor Lorna Casselton CBE FRS [1999] Dame Linda Partridge DBE FMedSci FRS [1996] Professor Deborah Charlesworth FRS [2005] Dr Barbara Pearse FRS [1988] Professor Jennifer Clack FRS [2009] Professor Fiona Powrie FRS [2011] Professor Nicola Clayton FRS [2010] Professor Susan Rees FRS [2002] Professor Suzanne Cory AC FRS [1992] Professor Daniela Rhodes FRS [2007] Dame Kay Davies DBE FMedSci FRS [2003] Professor Elizabeth Robertson FRS [2003] Professor Caroline Dean OBE FRS [2004] Dame Carol Robinson DBE FMedSci -
Clinical Molecular Genetics in the Uk C.1975–C.2000
CLINICAL MOLECULAR GENETICS IN THE UK c.1975–c.2000 The transcript of a Witness Seminar held by the History of Modern Biomedicine Research Group, Queen Mary, University of London, on 5 February 2013 Edited by E M Jones and E M Tansey Volume 48 2014 ©The Trustee of the Wellcome Trust, London, 2014 First published by Queen Mary, University of London, 2014 The History of Modern Biomedicine Research Group is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 0 90223 888 6 All volumes are freely available online at www.history.qmul.ac.uk/research/modbiomed/ wellcome_witnesses/ Please cite as: Jones E M, Tansey E M. (eds) (2014) Clinical Molecular Genetics in the UK c.1975–c.2000. Wellcome Witnesses to Contemporary Medicine, vol. 48. London: Queen Mary, University of London. CONTENTS What is a Witness Seminar? v Acknowledgements E M Tansey and E M Jones vii Illustrations and credits ix Abbreviations xi Ancillary guides xiii Introduction Professor Bob Williamson xv Transcript Edited by E M Jones and E M Tansey 1 Appendix 1 Photograph, with key, of delegates attending The Molecular Biology of Thalassaemia conference in Kolimbari, Crete, 1978 88 Appendix 2 Extracts from the University of Leiden postgraduate course Restriction Fragment Length Polymorphisms and Human Genetics, 1982 91 Appendix 3 Archival material of the Clinical Molecular Genetics Society 95 Biographical notes 101 References 113 Index 131 Witness Seminars: Meetings and Publications 143 WHAT IS A WITNESS SEMINAR? The Witness Seminar is a specialized form of oral history, where several individuals associated with a particular set of circumstances or events are invited to meet together to discuss, debate, and agree or disagree about their memories. -
Part I Officers in Institutions Placed Under the Supervision of the General Board
2 OFFICERS NUMBER–MICHAELMAS TERM 2009 [SPECIAL NO.7 PART I Chancellor: H.R.H. The Prince PHILIP, Duke of Edinburgh, T Vice-Chancellor: 2003, Prof. ALISON FETTES RICHARD, N, 2010 Deputy Vice-Chancellors for 2009–2010: Dame SANDRA DAWSON, SID,ATHENE DONALD, R,GORDON JOHNSON, W,STUART LAING, CC,DAVID DUNCAN ROBINSON, M,JEREMY KEITH MORRIS SANDERS, SE, SARAH LAETITIA SQUIRE, HH, the Pro-Vice-Chancellors Pro-Vice-Chancellors: 2004, ANDREW DAVID CLIFF, CHR, 31 Dec. 2009 2004, IAN MALCOLM LESLIE, CHR, 31 Dec. 2009 2008, JOHN MARTIN RALLISON, T, 30 Sept. 2011 2004, KATHARINE BRIDGET PRETTY, HO, 31 Dec. 2009 2009, STEPHEN JOHN YOUNG, EM, 31 July 2012 High Steward: 2001, Dame BRIDGET OGILVIE, G Deputy High Steward: 2009, ANNE MARY LONSDALE, NH Commissary: 2002, The Rt Hon. Lord MACKAY OF CLASHFERN, T Proctors for 2009–2010: JEREMY LLOYD CADDICK, EM LINDSAY ANNE YATES, JN Deputy Proctors for MARGARET ANN GUITE, G 2009–2010: PAUL DUNCAN BEATTIE, CC Orator: 2008, RUPERT THOMPSON, SE Registrary: 2007, JONATHAN WILLIAM NICHOLLS, EM Librarian: 2009, ANNE JARVIS, W Acting Deputy Librarian: 2009, SUSANNE MEHRER Director of the Fitzwilliam Museum and Marlay Curator: 2008, TIMOTHY FAULKNER POTTS, CL Director of Development and Alumni Relations: 2002, PETER LAWSON AGAR, SE Esquire Bedells: 2003, NICOLA HARDY, JE 2009, ROGER DERRICK GREEVES, CL University Advocate: 2004, PHILIPPA JANE ROGERSON, CAI, 2010 Deputy University Advocates: 2007, ROSAMUND ELLEN THORNTON, EM, 2010 2006, CHRISTOPHER FORBES FORSYTH, R, 2010 OFFICERS IN INSTITUTIONS PLACED UNDER THE SUPERVISION OF THE GENERAL BOARD PROFESSORS Accounting 2003 GEOFFREY MEEKS, DAR Active Tectonics 2002 JAMES ANTHONY JACKSON, Q Aeronautical Engineering, Francis Mond 1996 WILLIAM NICHOLAS DAWES, CHU Aerothermal Technology 2000 HOWARD PETER HODSON, G Algebra 2003 JAN SAXL, CAI Algebraic Geometry (2000) 2000 NICHOLAS IAN SHEPHERD-BARRON, T Algebraic Geometry (2001) 2001 PELHAM MARK HEDLEY WILSON, T American History, Paul Mellon 1992 ANTHONY JOHN BADGER, CL American History and Institutions, Pitt 2009 NANCY A. -
HUMAN GENE MAPPING WORKSHOPS C.1973–C.1991
HUMAN GENE MAPPING WORKSHOPS c.1973–c.1991 The transcript of a Witness Seminar held by the History of Modern Biomedicine Research Group, Queen Mary University of London, on 25 March 2014 Edited by E M Jones and E M Tansey Volume 54 2015 ©The Trustee of the Wellcome Trust, London, 2015 First published by Queen Mary University of London, 2015 The History of Modern Biomedicine Research Group is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 1 91019 5031 All volumes are freely available online at www.histmodbiomed.org Please cite as: Jones E M, Tansey E M. (eds) (2015) Human Gene Mapping Workshops c.1973–c.1991. Wellcome Witnesses to Contemporary Medicine, vol. 54. London: Queen Mary University of London. CONTENTS What is a Witness Seminar? v Acknowledgements E M Tansey and E M Jones vii Illustrations and credits ix Abbreviations and ancillary guides xi Introduction Professor Peter Goodfellow xiii Transcript Edited by E M Jones and E M Tansey 1 Appendix 1 Photographs of participants at HGM1, Yale; ‘New Haven Conference 1973: First International Workshop on Human Gene Mapping’ 90 Appendix 2 Photograph of (EMBO) workshop on ‘Cell Hybridization and Somatic Cell Genetics’, 1973 96 Biographical notes 99 References 109 Index 129 Witness Seminars: Meetings and publications 141 WHAT IS A WITNESS SEMINAR? The Witness Seminar is a specialized form of oral history, where several individuals associated with a particular set of circumstances or events are invited to meet together to discuss, debate, and agree or disagree about their memories. The meeting is recorded, transcribed, and edited for publication. -
Michaelmas Term 2002 Special No.6 Part I
2 OFFICERS NUMBER–MICHAELMAS TERM 2002 SPECIAL NO.6 PART I Chancellor: H.R.H. The Prince PHILIP, Duke of Edinburgh, T Vice-Chancellor: 1996, Prof. Sir Alec BROERS, CHU, 2003 Deputy Vice-Chancellors: for 2002–2003: A. M. LONSDALE, NH,M.J.GRANT, CL,O.S.O’NEILL, N, Sir ROGER TOMKYS, PEM,D.E.NEWLAND, SE,S.G.FLEET, DOW,G.JOHNSON, W Pro-Vice-Chancellors: 1998, A. M. LONSDALE, NH, 30 June 2004 2001, M. GRANT, CL, 31 Dec. 2004 High Steward: 2001, Dame BRIDGET OGILVIE, G Deputy High Steward: 1983, The Rt Hon. Lord RICHARDSON, CAI Commissary: 2002, Lord MACKAY, T Proctors for 2002–2003: J. D. M ACDONALD, CAI Deputy: D. J. CHIVERS, SE T. N. M ILNER, PET Deputy: V.E. IZZET, CHR Orator: 1993, A. J. BOWEN, JE Registrary: 1997, T. J. MEAD, W Deputy Registrary: 1993, N. J. B. A. BRANSON, DAR Secretary General of the Faculties: 1992, D. A. LIVESEY, EM Treasurer: 1993, J. M. WOMACK, TH Librarian: 1994, P.K. FOX, SE Deputy Librarians: 1996, D. J. HALL, W 2000, A. MURRAY, W Director of the Fitzwilliam Museum and Marlay Curator: 1995, D. D. ROBINSON, M Development Director: 2002, P.AGAR, SE Esquire Bedells: 1996, J. P.EMMINES, PET 1997, J. H. WILLIAMS, HH University Advocate: 1999, N. M. PADFIELD, F, 2003 Deputy University Advocate: 1999, P.J. ROGERSON, CAI, 2003 OFFICERS IN INSTITUTIONS PLACED UNDER THE SUPERVISION OF THE GENERAL BOARD PROFESSORS Accounting Vacant Aeronautical Engineering, Francis Mond 1996 W.N. DAWES, CHU Aerothermal Technology 2000 H. P.HODSON, G African Archaeology 2001 D. -
Trustees' Annual Report and Financial Statements 31 March 2016
THE FRANCIS CRICK INSTITUTE LIMITED A COMPANY LIMITED BY SHARES TRUSTEES’ ANNUAL REPORT AND FINANCIAL STATEMENTS 31 MARCH 2016 Charity registration number: 1140062 Company registration number: 6885462 The Francis Crick Institute Accounts 2016 CONTENTS INSIDE THIS REPORT Trustees’ report (incorporating the Strategic report and Directors’ report) 1 Independent auditor’s report 12 Consolidated statement of financial activities 13 Balance sheets 14 Cash flow statements 15 Notes to the financial statements 16 1 TRUSTEES’ REPORT (INCORPORATING THE STRATEGIC REPORT AND DIRECTORS’ REPORT) The trustees present their annual directors’ report together with the consolidated financial statements for the charity and its subsidiary (together, ‘the Group’) for the year ended 31 March 2016, which are prepared to meet the requirements for a directors’ report and financial statements for Companies Act purposes. The financial statements comply with the Charities Act 2011, the Companies Act 2006, and the Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK (FRS102) effective 1 January 2015 (Charity SORP). The trustees’ report includes the additional content required of larger charities. REFERENCE AND ADMINISTRATIVE DETAILS The Francis Crick Institute Limited (‘the charity’, ‘the Institute’ or ‘the Crick) is registered with the Charity Commission, charity number 1140062. The charity has operated and continues to operate under the name of the Francis Crick -
80 Stephen Paget Memorial Lecture and Openness Awards Ceremony 5
80th Stephen Paget Memorial Lecture and Openness Awards Ceremony 5th December 2016 Royal College of Physicians, London #ConcordatOpenness Programme 18:00 Arrival and Refreshments 18:30 Welcome Address 18:40 Openness Awards Internal or sector engagement activity Public engagement activity Media engagement or media stories Website or use of new media Individual award 19:00 80th Paget Lecture by Professor Sir Mark Walport Animal Research – Then and Now 20:00 Drinks Reception 21:30 End The Stephen Paget Memorial Lecture The Stephen Paget Memorial Lecture is a scientific lecture to commemorate the life of Dr Stephen Paget. Stephen Paget (1855 – 1926) was the founder of the Research Defence Society, a forerunner of Understanding Animal Research. He believed passionately that better science and understanding of physiology would lead to better medical treatments. After his death in 1926, he was greatly missed by his medical colleagues and the scientific community. The first Stephen Paget memorial lecture was given in 1927 to commemorate his life and allow leading bio-medical scientists of the day to talk about their research. The Openness Awards The Concordat on Openness launched in May 2014 and has to date brought together 109 organisations in a pledge to be more open and transparent about the use of animals in research. This year the Openness Awards celebrate five recipients that have met the Concordat commitments and encouraged the widespread sharing of best practice. Professor Sir Mark Walport, FRS, FMedSci Sir Mark is the Chief Scientific Adviser to HM Government and Head of the Government Office for Science. Previously, Sir Mark was Director of the Wellcome Trust. -
Staff Changes Emma Bennett Joined the Academy As Exhibits Regularly in the UK and Europe
Council Election Nobel Prize Congratulations to the following Fellows who Dr Sydney Brenner were elected to serve as new members of FRS HonFMedSci was awarded The Council with effect from 21 November 2002. Nobel Prize in Physiology or Medicine for 2002 for his research into genetic regulation of organ development and Professor Carol Black programmed cell death. Though now based in California, President, The Royal College of Physicians and Professor of Sydney Brenner’s discoveries whilst working in Cambridge, Rheumatology, Royal Free and University College Medical School UK, laid the foundation for this year’s prize which was awarded jointly to H Robert Horvitz and John E Sulston. Professor Nancy Rothwell MRC Research Professor, University of Manchester Professor Julia Goodfellow Chief Executive, the Biotechnology and Biological Sciences Research Council Professor Colin Bird Sir Douglas Black Formerly Dean of Medicine and Provost of Faculty Group of Medical and Veterinary Medicine, University of Edinburgh Sir Douglas Black: died September 13, 2002. It is with Medical School much sadness that we record the passing of a distinguished Honorary Fellow. The Black report was widely Professor Jonathan Cohen regarded as the most authoritative publication on the link Dean, Brighton & Sussex Medical School between poor health and social deprivation. That it became Professor Thomas Kirkwood so influential was at least in part due to the then Professor of Medicine, University of Newcastle Upon Tyne Government’s efforts to suppress its publication. Council is pleased to announce the appointment of Sir John Skehel, Sir Douglas was a widely respected and much loved FRS FMedSci, as Shadow Vice-President with responsibility for Professor of Medicine at Manchester and later President of non-clinical affairs. -
Life Changing Science
LIFE CHANGING SCIENCE The Francis Crick Institute Annual Review 2017/18 AN INSTITUTE FOR DISCOVERY Our commitment to excellence, our emphasis on multidisciplinary research, our focus on young and emerging talent and our novel ways of partnership working are some of the factors that set the Crick apart. Front cover Vaccinia virus infection (green) disrupts a layer of epithelial cells (red/blue). Courtesy of Michael Way, Group Leader at the Crick. INTRODUCTION 2 Who we are Our year at a glance 2 Introduction by Paul Nurse 4 The Francis Crick Institute is a biomedical Progress against our strategy 6 discovery institute dedicated to understanding the RESEARCH HIGHLIGHTS 10 Cancer-causing mutation fundamental biology underlying health and disease. suppresses immune system 11 Our work is helping to build an understanding of Predicting lung cancer’s return 12 New understanding of human why disease develops and to translate discoveries embryo development 14 Chemical attraction could improve into new ways to prevent, diagnose and treat cancer immunotherapy 16 illnesses such as cancer, heart disease, stroke, Genes linked to malaria parasites’ persistence 17 infections and neurodegenerative diseases. Architecture of our ‘second brain’ 18 Cause of infertility side-stepped in mice 19 Mechanism for spinal cord development discovered 20 A new layer of complexity in embryo development 21 Two DNAs wedded with this ring 22 Unravelling how DNA gets copied 23 Telomerase’s dark side discovered 24 REVIEW OF THE YEAR 26 New group leaders arrive 27 Joined-up thinking 30 Focusing on the molecules of life 32 CryoEM at the Crick 34 Bringing academia and industry closer together 36 The people making research happen 38 Patterns in art and science 40 Rewarding research 42 Appointments 43 Supporting new discoveries 44 Our vision What’s inside Our vision is to be a world- We bring together outstanding scientists Science feature 32 leading multidisciplinary from all disciplines and carry out research Sophisticated microscopy is being biomedical research institute. -
ITMAT 11 Annual International Symposium Monday and Tuesday, October 17-18, 2016 Perelman School of Medicine, University of Penns
ITMAT 11th Annual International Symposium Monday and Tuesday, October 17-18, 2016 Perelman School of Medicine, University of Pennsylvania Smilow Center for Translational Research (SCTR) The Arthur Rubenstein Auditorium 3400 Civic Center Boulevard, Philadelphia, PA Translational Science in the Era of Precision Medicine Monday, October 17 (Day 1) 8:00 AM Registration and Breakfast: Smilow Lobby 8:45 Introduction J. Larry Jameson, MD, PhD, Executive Vice President, University of Pennsylvania for the Health System, and Dean, Perelman School of Medicine, University of Pennsylvania Session 1: Precision Medicine Initiatives at Scale Session Chairs: Sir Keith Peters, FRCP, FRS, FMedSci, Emeritus Regius Professor of Physic, University of Cambridge, Consultant in Clinical Science and Translational Medicine to the Francis Crick Institute and Senior Consultant in R&D to GlaxoSmithKline and Jonathan A. Epstein, MD, Executive Vice Dean and Chief Scientific Officer, Perelman School of Medicine, University of Pennsylvania 9:00 Genes, Genomes and the Future of Medicine Richard Lifton, MD, PhD, President, Rockefeller University 9:30 Precision Medicine and Global Health Ezekiel J. Emanuel, MD, PhD, Vice Provost for Global Initiatives, Chair, Department of Medical Ethics and Health Policy, University of Pennsylvania 10:00 Precision Medicine in the UK: from 100,000 Whole Genomes to 65 Million Patients Professor Sir John Savill, MB ChB, PhD, FRS, Chief Executive, Medical Research Council UK 10:30 COFFEE: Smilow Lobby Session 2: The Biology of Senescence Session Chairs: Virginia M.-Y. Lee, PhD, Professor of Pathology and Laboratory Medicine, Director, The Center for Neurodegenerative Disease Research at the Perelman School of Medicine of the University of Pennsylvania and Nancy M. -
Dame Bridget Ogilvie Hon Dsc
Dame Bridget Ogilvie Hon DSc Oration by Professor Richard Lilford Warwick Medical School Dame Bridget Ogilvie Hon DSc Professor Dame Bridget Ogilvie is, as her titles suggest, a person of But it was time for Bridget to move on. It is easy to attribute exceptional achievement. scientific discovery to us scientists. But modern scientists are dependent on how science is funded and governed. So in 1981 Bridget grew up on an Australian sheep farm and this engendered, Bridget decided to stretch her wings, and accept a senior science in her receptive mind, an interest in the animals she saw around policy role at the Wellcome Trust, rising to become its Director in her, in the diseases that afflict the animals and, in due course, in 1991. The Wellcome Trust is the world’s second largest medical the power of science to transform animal husbandry. Bridget also charity, after the Bill and Melinda Gates Foundation, and currently had educational advantages – her father was an alumnus of Oxford invests over £1 billion in research each year. Bridget established University (no University of Warwick in those days) and she had the the Sanger Centre in Cambridge, the first centre in the world to benefit of an exceptional teacher at her local village school – one sequence the human genome. AB Clark. A fascination with life in all its forms, and her passion for education, run like a thread through her career. She also increased the rate at which scientific discoveries are translated into practical improvements by sponsoring Clinical Bridget started higher education at Queensland University, but her Tropical Medicine Centres and our previous Dean of Medicine, ‘pure science’ course failed to excite her imagination so, on learning Professor Peter Winstanley, was director of such a centre. -
Editor Sir Michael Pepper FRS Publishing Editor Suzanne Abbott
RSTA_368_1914_cover.qxd 01/21/10 12:05 PM Page 2 GUIDANCE FOR AUTHORS Editor Selection criteria computer programs. However, the printed version must Sir Michael Pepper FRS The criteria for selection are scientific excellence, include enough detail to satisfy most non-specialist readers. originality and interest across disciplines within the Supplementary data up to 10Mb is placed on the Society's Publishing Editor physical sciences and engineering, including mathematics website free of charge. Larger datasets must be deposited Suzanne Abbott and Earth science. The Editors are responsible for all in recognised public domain databases by the author. editorial decisions and they make these decisions based on the reports received from the referees and/or Editorial Conditions of publication Editorial Board Board members. Many more good proposals and articles Articles must not have been published previously, nor are submitted to us than we have space to print, and we be under consideration for publication elsewhere. The Michael Pepper, Editor Brian Launder give preference to those that are of broad interest and of main findings of the article should not have been London Centre for Nanotechnology and Department of Electronic and School of Mechanical, Aerospace and Civil Engineering, Electrical Engineering, University College London University of Manchester high scientific quality. reported in the mass media. Like many journals, Phil. Russel Caflisch Alan Martin Trans. R. Soc. A employs a strict embargo policy where Department of Mathematics, University of California, Los Angeles Department of Physics, Durham University Publishing format the reporting of a scientific article by the media is Peter Coveney William McGuire Centre for Computational Science, University College London Department of Earth Sciences, University College London Phil.