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Detection and Characterization of a Novel Bat-Borne Coronavirus in Singapore Using Multiple Molecular Approaches
RESEARCH ARTICLE Lim et al., Journal of General Virology 2019;100:1363–1374 DOI 10.1099/jgv.0.001307 Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches Xiao Fang Lim1,2, Chengfa Benjamin Lee3, Sarah Marie Pascoe3, Choon Beng How3, Sharon Chan3, Jun Hao Tan1, Xinglou Yang1,4, Peng Zhou4, Zhengli Shi4, October M. Sessions1,5,6, Lin-Fa Wang1, Lee Ching Ng2, Danielle E. Anderson1,* and Grace Yap2,* Abstract Bats are important reservoirs and vectors in the transmission of emerging infectious diseases. Many highly pathogenic viruses such as SARS-CoV and rabies-related lyssaviruses have crossed species barriers to infect humans and other animals. In this study we monitored the major roost sites of bats in Singapore, and performed surveillance for zoonotic pathogens in these bats. Screening of guano samples collected during the survey uncovered a bat coronavirus (Betacoronavirus) in Cynopterus brachyotis, commonly known as the lesser dog-faced fruit bat. Using a capture-enrichment sequencing platform, the full- length genome of the bat CoV was sequenced and found to be closely related to the bat coronavirus HKU9 species found in Leschenault’s rousette discovered in the Guangdong and Yunnan provinces. INTRODUctiON CoVs in general can cause disease in a variety of domestic and Infectious diseases continue to be a major threat to modern wild animals, as well as in humans, whereas alpha- and beta- society and coronaviruses (CoVs) are one of the most notable coronaviruses predominantly infect mammals. SARS-CoV virus families responsible for recent, highly pathogenic viral and MERS-CoV belong to the genus Betacoronavirus, under disease outbreaks. -
Participating Outlets
Participating Outlets No Name of customer Address Postal Code 1 4Fingers Terminal 3 65 Airport Boulevard, #B2-02 Changi Airport Terminal 3 819663 2 4Fingers Northpoint 930 Yishun Avenue 2, #01-15 769098 3 4Fingers Tiong Bahru Plaza 302 Tiong Bahru Road, Tiong Bahru Plaza #01-105 168732 4 4Fingers Terminal 1 80 Airport Boulevard, #03-47 Terminal 1 Departure/Transit Lounge East, Singapore Changi Airport 819642 5 4Fingers ION Orchard 2 Orchard Turn, #B4-06A 238801 6 4Fingers Jurong Point 1 Jurong West Central 2, #03-34 648886 7 4Fingers Orchard Gateway 277 Orchard Road, #01-04/05 Orchard Gateway 238858 8 4Fingers West Gate 3 Gateway Dr, #02-05 608532 9 4Fingers Plaza Singapura 68 Orchard Rd, #B1-07 238839 10 4Fingers Tampines 1 10 Tampines Central 1, #01-39/40 529536 11 4Fingers Marina Square 6 Raffles Boulevard Marian Square #02-183A 39594 12 4Fingers Causeway Point 1 Woodland Square #01-38/39 738099 13 Pepper Lunch Houganag Mall 90 Hougang Avenue 10 #B1-24/25/26 538766 14 Pepper Lunch AMK Hub 53 Ang Mo Kio Ave 3 AMK Hub #01-34 569933 15 Pepper Lunch Compass One 1 Sengkang Square, #B1-01, Compass One 545078 16 Pepper Lunch JEM 50 Jurong Gateway Road, #04-10/11/12, JEM 608549 17 Pepper Lunch Jurong Point 63 Jurong West Central 3, #B1-62/63 JP2, 648331 18 Pepper Lunch Orchard Cineileisure #05-03, 8 Grange Road 239695 19 Pepper Lunch Bedok Mall 311 New Upper Changi Road #01-05/06/07/08 467360 20 Pepper Lunch Tapines 1 10 Tampines Central 1 #B1-06 529536 21 LJS Bedok Point 799 New Upper Changi Road #01-02/03 Singapore 467351 467351 22 LJS Bugis -
Isoteam Ltd. Date: 30 August 2019
ISOTeam Ltd. Date: 30 August 2019 BUY Target Price: S$0.325 FY19 revenue surged 63.0% (Maintained) (+38.5%) ISOTeam Ltd, and together with its subsidiaries ISOTeam (5WF.SI) (“ISOTeam” or the “Company”, or the “Group”) reported Price: S$0.235 (as at 29 August 2019) a revenue of S$136.6 million for FY19, a 63.0% increase S$ as compared to the S$83.8 million recorded in FY18. In addition, other income also rose S$1.4 million or 67.2% to 0.35 S$3.1 million mainly due to fair value gain on investment, which was partially offset by a decrease in government 0.30 grants received. In tandem with the strong revenue growth and an increase in other income, ISOTeam achieved a net 0.25 attributable profit of S$6.8 million in FY19 as compared to the restated net attributable profit of S$0.5 million in FY18. 0.20 Poised for greater growth. Driven by the revised tendering 0.15 strategy, ISOTeam is able to secure more and relatively Aug-2018 Nov-2018 Feb-2019 May-2019 Aug-2019 higher margin contracts. As at 31 July 2019, ISOTeam’s Share price 1M 3M 6M 1Y order book stood at S$113.5 million which is expected to be progressively delivered over the next two years. Recently, ISOTeam Ltd. -4.1% 6.8% 14.6% -16.1% the proposed acquisition of Pure and their entry into an -7.0% -4.1% -9.3% -28.2% Catalist Index asset transfer agreement with Singapore Mobike are also Market capitalisation S$66.7 million expected to contribute positively to the Group going forward. -
MEDIA RELEASE for Immediate Release
MEDIA RELEASE For Immediate Release New National Masterplan to Encourage More to Garden - NParks takes over development of the Orchid Industry Singapore, 3 November 2017- The National Parks Board (NParks) today announced a new national gardening masterplan for Singapore which centres on promoting edible gardening. The masterplan will be implemented through both ongoing and new initiatives such as training, the expansion of the allotment gardening scheme, as well as outreach efforts like the Community Garden Festival. With a large number of community gardeners growing edibles, the Edible Horticulture Masterplan aims to increase knowledge and cultivate the community’s interest in gardening by opening up more avenues for the public to participate in Singapore’s greening efforts. During the opening of the Community Garden Festival at HortPark, NParks also unveiled HortHouse, which will serve as the new training hub for the Centre for Urban Greenery and Ecology (CUGE). This new landscape fronting HortHouse featuring eleven families of flowers and foliage will also provide an outdoor showcase of horticultural varieties to complement learning, and appeal to home gardeners. The focus on edibles taps on the immense interest in edible gardening to nurture younger gardeners. After more than a decade since the establishment of the Community in Bloom programme, community gardeners have honed their skills in growing edibles. At present, 80% of the gardening groups in HDB estates grow edibles in their community gardens. This burgeoning interest in edibles is also evident in the increasing number of entries in the NParks Community Garden Edibles Competition each year. There were a record number of 400 participants in this year’s competition, an approximately 33% increase from the previous year, in addition to an overall improvement in the quality of entries as the competition enters its third year. -
Living with Nature Content
ANNUAL REPORT 2018/2019 Living with Nature Content 02 CHAIRMAN’S MESSAGE 04 MEMBERS OF THE BOARD 06 MANAGEMENT TEAM 08 ORGANISATION STRUCTURE 10 THRIVING GREENERY 20 A BIOPHILIC HOME 28 A GROWING INTEREST 36 NURTURING THE FIELD 44 GARDEN CITY FUND 48 SUSTAINABILITY REPORT 52 FACTS & FIGURES 58 CORPORATE GOVERNANCE 60 PUBLICATIONS 66 FINANCIAL REVIEW 70 FINANCIAL STATEMENTS Forest Walk of Telok Blangah Hill Park When our History and Natural Heritage intersect n 2019, Singapore celebrates 200 years of the intersection between our history and our natural heritage – entrenched in our nature ways and nature reserves, our parks and park Iconnectors, as well as our flora and fauna. The idea for a national garden was planted in 1822 when Sir Stamford Raffles, the founder of modern Singapore, developed the first Botanical and Experimental Garden at Fort Canning. In 1859, the Singapore Botanic Gardens was established at the Tanglin site and in the 160 years past, it has flourished from a pleasure garden for the colonial community to a place cherished by all Singaporeans, a botanical institution known internationally. Singapore’s greening journey took root in the 1960s when founding Prime Minister, Mr Lee Kuan Yew planted a Mempat Tree at Farrer Circus. This kickstarted a national effort for tree planting, sowing the seed of a green home where beautiful parks and green belts would be the birthright of every Singaporean. Today, the intricate lattice of greenery we have woven into the cityscape supports thriving biodiversity and provides residents with a quality living environment. This not only draws the appreciation and marvel of visitors, but has become a part of our national identity. -
Factsand Figures
52.53 FactsAnd Figures Indicators FY 2001 FY 2002 FY 2003 FY 2004 FY 2005 FY 2006 FY 2006 Target WITS Participation Rate (%) 100.00 100.00 100.00 100.00 100.00 100.00 100.00 WITS Project Ratio (%) 212.00 188.00 190.00 181.00 172.00 171.00 170.00 WITS Implementation Ratio (%) 100.00 100.00 100.00 100.00 100.00 100.00 100.00 SSS Participation Rate 100.00 100.00 100.00 100.00 100.00 100.00 100.00 SSS Suggestion Ratio 5.30 5.23 5.07 5.10 5.20 5.20 5.00 SSS Implementation Ratio 0.67 0.63 0.78 0.60 0.62 0.59 0.53 Awards Bridge of Hope Award SHARE Gold Award Excellent Service Award – 1 Star, 6 Gold and 3 Silver 5-Year Outstanding SHARE Award Green Mark Award – 1 Gold Plus and 2 Gold Singapore HEALTH Award – Platinum ISO 9001:2000 Recertification Singapore Innovation Class National IQC Convention – 2 Gold and 1 Star Staff Information Staff Strength 16% Breakdown of Staff Strength 766 by Educational Level Staff Turnover 31.7% Degree & above 243 0.99% Diploma 115 Training Places GCE “A” Level 59 98.07% 29.6% Secondary & “O” Level 227 Primary & below 122 15.0% Total 766 7.7% Regional Parks & Recreation Areas Managed by NParks Area (ha) Area (ha) Ang Mo Kio Town Garden East 4.88 Marina Promenade 8.17 Ang Mo Kio Town Garden West 20.63 Mount Faber Park 56.46 Bedok Reservoir Park 42.62 One-North Park 3.31 Bedok Town Park 14.62 Pasir Ris Park 70.52 Bishan Park 60.24 Pasir Ris Town Park 14.01 Bukit Batok Nature Park 35.74 Pearl’s Hill City Park 8.50 Bukit Timah Nature Reserve 162.64 Pulau Ubin Recreation Area Central Catchment Nature Reserve 455.00 (including -
Title Ecology of Long-Tailed Macaques (Macaca
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Kyoto University Research Information Repository Ecology of Long-Tailed Macaques (Macaca fascicularis) and Title its Implications for the Management of Human-Macaque Interface in Singapore( Dissertation_全文 ) Author(s) John Sha Chih Mun Citation Kyoto University (京都大学) Issue Date 2014-03-24 URL http://dx.doi.org/10.14989/doctor.r12814 許諾条件により本文は2014-10-01に公開; ここに掲載した 著作物の利用に関する注意 本著作物の著作権は、著者、 日本哺乳類学会、Wiley社、Springer社に帰属します。本 著作物はこれらの著作権者の定めた条件に従って公開す るものです。ご利用に当たっては「著作権法」に従うこ とをお願い致します。出典は下記の通りです。; 第2章 :Sha JCM, Gumert MD, Lee BPYH, Fuentes A, Rajathurai S, Chan S, Jones-Engel L (2009) Status of the long‐tailed macaque Macaca fascicularis in Singapore and implications for management. Biodiversity and Conservation 18(11) 2909- 2926. DOI: 10.1007/s10531-009-9616-4; 第3章:Sha JCM, Right Gumert MD, Lee BPYH, Jones-Engel L, Chan S, Fuentes A (2009) Macaque-human interactions and the societal perceptions of macaques in Singapore. American Journal of Primatology 71(10)825-839. DOI: 10.1002/ajp.20710; 第4章 :Sha JCM & Hanya G (2013) Diet, activity, habitat use and ranging of two neighboring groups of food-enhanced long- tailed macaques (Macaca fascicularis). American Journal of Primatology 75(6): 581-592. DOI: 10.1002/ajp.22137; 第5章 :Sha JCM & Hanya G (2013) Temporal food resource correlates to the behavior and ecology of food-enhanced long- tailed macaques (Macaca fascicularis). Mammal Study 38 (3): 163-175. Type Thesis or Dissertation Textversion ETD Kyoto University 主論文 Thesis Ecology of Long-Tailed Macaques (Macaca fascicularis ) and its Implication for the Management of Human-Macaque Interface in Singapore John Sha Chih Mun Primate Research Institute, Kyoto University December, 2013 Table of Contents ACKNOWLEDGEMENT ........................................................................................... -
Detection and Characterization of a Novel Bat-Borne Coronavirus in Singapore Using Multiple Molecular Approaches
RESEARCH ARTICLE Lim et al., Journal of General Virology 2019;100:1363–1374 DOI 10.1099/jgv.0.001307 Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches Xiao Fang Lim1,2, Chengfa Benjamin Lee3, Sarah Marie Pascoe3, Choon Beng How3, Sharon Chan3, Jun Hao Tan1, Xinglou Yang1,4, Peng Zhou4, Zhengli Shi4, October M. Sessions1,5,6, Lin-Fa Wang1, Lee Ching Ng2, Danielle E. Anderson1,* and Grace Yap2,* Abstract Bats are important reservoirs and vectors in the transmission of emerging infectious diseases. Many highly pathogenic viruses such as SARS-CoV and rabies-related lyssaviruses have crossed species barriers to infect humans and other animals. In this study we monitored the major roost sites of bats in Singapore, and performed surveillance for zoonotic pathogens in these bats. Screening of guano samples collected during the survey uncovered a bat coronavirus (Betacoronavirus) in Cynopterus brachyotis, commonly known as the lesser dog-faced fruit bat. Using a capture-enrichment sequencing platform, the full- length genome of the bat CoV was sequenced and found to be closely related to the bat coronavirus HKU9 species found in Leschenault’s rousette discovered in the Guangdong and Yunnan provinces. INTRODUctiON CoVs in general can cause disease in a variety of domestic and Infectious diseases continue to be a major threat to modern wild animals, as well as in humans, whereas alpha- and beta- society and coronaviruses (CoVs) are one of the most notable coronaviruses predominantly infect mammals. SARS-CoV virus families responsible for recent, highly pathogenic viral and MERS-CoV belong to the genus Betacoronavirus, under disease outbreaks. -
Illustrated Plans
K I N L T H R O N N R YISHUN TA E E L S HOUSING & TRANSPORT S E L E TA R N O R T H L I N K Lentor Hills NORTHSHORE DRIVE KHATIB E PUNGGOL POINT I V R D E SAMUDERA C A Punggol Point P PUNGGOL COAST S D O A R P UNGGO O E L CO R A A ERO S A S R T P PA R C A D M R E T TECK LEE A E A V T IE L C E L W E E S T S NIBONG SE S SAM KEE LO E L C K W O N G I G L N T U S P E W R P SELETAR LINK A I T C L E C S E A SUMANG D S I E L L L E Y P T U A N R G G S E A O L E E E L T V R N A I O R R O SUMANG WALK PUNGGOL DRIVE A D S R E R E P SOO TECK PUNGGOL WALKPUNGGOL DAMAI T O S PA C A H C L E I N W K A Y PUNGGOL CENTRAL TA M P I N E S E X P R E S S W AY OASIS PUNGGOL ROAD PUNGGOL WAY PUNGGOL FIELD FERNVALE STREET KADALOOR A COVE NCHORV FARMWAY ALE STR SPRINGLEAF EET KUPANG CHENG LIM TA X P R E S S W AY THANGGAM M TA R E P L E I N MERIDIAN S E D PUNGGOL EAST A E S O S E N G R K JALAN KAYU A N G E A S T W AY R E T IVE X S R VA E L P RIVIERA COMPASSVALE E D R Y W R A I S E L E S S W VE E T E G A R E X P R L S CORAL EDGE E N NT FERNVALE LINK S OR D A A A K FERNVALE ROAD W V O K E R G N G N A I U N N SENGK E A ANG W LAYAR S L Y K E EST AVE E NUE FERNVALE N E U S G CH K L SENGKANG RUMBIA A A IO YIO NG V Y CHU R O KA NG H R OA E C D A ST N A A SENGKANG EAST ROAD TONGKANG V EN U N E UPPER THOMSON ROAD Y O GERALD DRIVE PUNGGOL ROAD BAKAU A R S EN D T W G A K BUANGKOK DRIVE A H S RENJONG O N G SENGKANG EAST DRIVE R S - N S E O D S O R A M U O O LENTOR P R E H A T X S T R K RANGGUNGT R N KANGKAR H A I E E T L P A E K BUANGKOK V P E U L O L E K D L S G C O A N A B O -
Home News Apr-Jul 2013.Pdf
Home News is published by Far East Organization Centre Pte Ltd (Registration No: 197001007E). Copyright of the material contained in this newsletter belongs to Far East Organization. Nothing in here shall be reproduced in whole or in part in any form or by any means, electronic, mechanical, photocopying, recording or otherwise without prior written consent of Far East Organization. For enquiries please contact [email protected]. Printed by RR Donnelley. l HOME NEWS thisissue l this issue elcome to Far East Organization’s Home News magazine, published three times a year for Far East homeowners. This issue, we explore different Waspects of sophisticated living in cosmopolitan Singapore. Our pictorial feature on Singapore’s Land Use Plan highlights the Singapore Government’s strategies to achieve a high quality living environment for all residents. In our Property Highlights Special, we shine the spotlight on luxurious penthouse living with a selection of penthouses available in Far East Organization developments. Readers moving into their new homes can turn to the article on putting together fuss-free housewarming parties with good food – with expert advice from gourmet grocer, Dean & DeLuca. Also check out our new House Wise section for fast facts on fire and safety, robotic cleaners and other practical know-hows to help make your home a safe and efficient one. Last but not least, find out how your new property is coming along in the second half of the magazine which contains the latest TOP updates and construction status details of new developments. Happy reading! PASTA DINNER If you’re having a weekday dinner with close friends or colleagues, the main course has to be hearty and easy to prepare. -
Singapore Raptor Report February 2017
Singapore Raptor Report February 2017 Chinese Sparrowhawk, adult female, Ang Mo Kio, 17 Feb 2017, by Tan Gim Cheong. Summary for migrant species: In February, 66 individuals of 7 migrant species were recorded. While the 26 Oriental Honey Buzzards were similar to last February's numbers, the 19 Black Bazas represented a drop of more than half compared to last February. All the Black Bazas were recorded at the Punggol - Pasir Ris - Tampines area. Six Jerdon's Baza were recorded, five at Punggol on the 4th and one at Pasir Ris Park on the 12th, good numbers for this species. Of the six Peregrine Falcons recorded, two adults were photographed fighting at Seletar Airport vicinity on the 27th. Three Japanese Sparrowhawks were recorded; two of them, adult males, on the 6th at Changi Business Park and 10th at Bidadari, showed signs of moult, similar to what was observed last February, and had only 4 'fingers' instead of the usual 5 'fingers'. Five Ospreys were recorded, including three over Bukit Timah Hill on the 20th. Two Chinese Sparrowhawks were recorded, one at Kent Ridge Park on the 2nd and another, an adult female, at Ang Mo Kio on the 5th, 17th and 19th. A Crested Serpent Eagle photographed at Kent Ridge Park on the 10th by Gavan Leong turned out to be a 3rd year burmanicus, thanks to Dr Chaiyan for his expertise. This is the second occurrence of the burmanicus form, a short distance migrant from Indo-China, to Singapore. The previous record was in September and November 2014 when an individual was photographed at the Japanese Gardens. -
Singapore Raptor Report Feb16
Singapore Raptor Report Spring Migration, February 2016 Common Kestrel, adult male, Pulau Punggol Barat, 23 Feb 16, by Alfred Ng. Summary for migrant species: The Black Baza again claimed the top spot with 54 birds; the largest gathering was a flock of 21 birds at the Lorong Halus area. The Oriental Honey Buzzard was well represented by 30 birds, some of which had perched in urban areas such as the top of apartments. Five Japanese Sparrowhawks were recorded; at this time of the year, most of them showed signs of moult (which could make their wings look more pointed) and may be confused with the Chinese Sparrowhawk. Four Peregrine Falcons were recorded; among these, the 3 photographed were adults of the migrant race. Three Ospreys were recorded; 2 on the northern shores and 1 in the Central Catchment area. Two Jerdon's Bazas continued to winter at Tampines Eco Green; providing opportunities for birders to see this uncommon migrant. The juvenile Chinese Sparrowhawk with the falconry jesses on both tarsus was photographed again at Bidadari on the 18th. The uncommon Common Kestrel, a male, wintering at Punggol Barat was photographed on the 7th and the 23rd. An adult dark morph Common Buzzard was photographed at Changi on the evening of the 24th. There was a sighting report of a juvenile Rufous-bellied Hawk- Eagle at Labrador Park on the 16th; it may be useful to note that confusion with juvenile Changeable Hawk Eagle cannot be ruled out without photos. Lastly, a nocturnal raptor, the Northern Boobook (first discovered at Pasir Ris Park mangroves on 31st Jan) was photographed on the 1st and 2nd of Feb, after which it was not located again.