12Th Annual Susan G. Komen St. Louis Race for the Cure® Locally Presented by Wells Fargo Advisors Saturday, June 12, 2010 - Downtown St

12th Annual Susan G. Komen St. Louis Race for the Cure® locally presented by Wells Fargo Advisors Saturday, June 12, 2010 - Downtown St. Louis

12th Annual Susan G. Komen St. Louis Race for the Cure®, locally presented by Wells Fargo Advisors, is June 12 – New competitive run added this year

The 12th Annual Susan G. Komen St. Louis Race for the Cure®, locally presented by Wells Fargo Advisors, will take place Saturday, June 12 in downtown St. Louis. The Race will begin at 8:30 a.m. with the wheelchair start, followed by the 5K timed runners start at 8:35 a.m. At 8:40 a.m., the 5K untimed runners start followed by a 9 a.m. start for all 5K walkers. The 1-Mile Fun Walkers start at 9:15 a.m. The Saint Louis Athletica, a founding member of women’s professional soccer, will serve as Race Honorary Co-Chairs. The Komen St. Louis Race for the Cure® is the world’s largest 5K event!

More than 66,000 people participated in the 2009 Race and $3.25 million in net proceeds were raised. This year, organizers expect more than 60,000 participants and have a goal to raise $3.5 million in net proceeds. Up to seventy- five percent of the net money raised by the Komen St. Louis Affiliate stays in the St. Louis area to fund screening, treatment, education and research programs. A minimum of twenty-five percent of money raised goes to the National Susan G. Komen for the Cure® Grants Program to fund research.

Visit www.komenstlouis.org to register online for this year’s Race. Registration forms are available at FLEET FEET Sports stores, New Balance stores (2 locations), Saint Louis Bread Co. stores, Schnucks Supermarkets and Wehrenberg Theatres.

This year, the Komen St. Louis Race for the Cure will include a timed run, sponsored by FLEET FEET Sports. For serious runners and those who would simply like their exact time for the 5K, this will be a great opportunity to make a real difference in the fight against breast cancer while pursuing personal running and fitness goals.

By registering for the Race, participants are automatically enrolled in the Friends for the Cure Pledge Program which allows individuals to raise money to provide screening, treatment, education and research programs in the St. Louis area. Through an easy online site, each participant receives a fundraising Web page that can be personalized. Friends and family can go to the participant’s page to make donations in support of their efforts to find the cures for breast cancer.

Survivors are the stars of the Komen St. Louis Race for the Cure and an inspiration. Registered breast cancer survivors will again receive a pink t-shirt and complimentary cap provided by Zeta Tau Alpha, sponsor of the Breast Cancer Survi- vor Recognition Program. In addition, breast cancer survivors can meet on Race Day at the Schnucks Survivor Pavilion and enjoy complimentary breakfast items and a photo booth.

The National Presenting Sponsor of the Susan G. Komen Race for the Cure Series is Yoplait. National Series Sponsors are American Airlines, Ask.com, Bank of America, Ford Division, New Balance Athletic Shoe, Inc. and RE/MAX Interna- tional.

The local presenting sponsor is Wells Fargo Advisors.

Platinum sponsors are Anheuser-Busch, KSDK NewsChannel 5, Siteman Cancer Center and Yurbuds. Gold sponsors are Anthem Blue Cross Blue Shield, CIGNA, Edward Jones, Express Scripts Foundation, Schnuck Markets, Inc., St. Louis Magazine and Wehrenberg Theatres. Silver sponsors are Best Buy, David C. Pratt Cancer Center, Lumière Place Casino and Hotels, Macy’s, McCarthy Building Companies, Inc., River City Casino, SchoolReach, St. Louis Cancer & Breast Institute, The Breast HealthCare Center at Missouri Baptist and The Printing Source. Bronze sponsors are CBL Properties, Denny’s, Dowd Bennett LLP, Emerson, Glory Foods, Metro, Regions Bank and SSM Cancer Care.

The Survivor Pavilion sponsor is Schnuck Markets, Inc. The Kids Corner sponsor is Wells Fargo Advisors and this year’s Teams sponsor is the St. Louis Cardinals.

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2010 Honorary Co-Chairs

Saint Louis Athletica, a founding member of Women’s Professional Soccer (WPS), will serve as Honorary Co-Chairs of the 12th Annual Susan G. Komen St. Louis Race for the Cure.

“On behalf of all my teammates, and everyone in the Saint Louis Athletica organization, I would like to say how proud we are to have been chosen as the honorary co-chairs for this year’s St. Louis Race for the Cure,” said Athletica Captain Lori Chalupny. “Many of my teammates, and me included, know someone that has been affected by breast cancer. As a team, we are excited to have the opportunity to use our platform in the WPS to be able to help further raise awareness and funds so together we can end breast cancer forever.”

The young and talented soccer club located right here in St. Louis got underway last year with its inaugural season. In 2009, Athletica finished in second place in the WPS, and reached the WPS Super Semifinal. Saint Louis Athletica plays their home matches at The Anheuser-Busch Soccer Park in suburban St. Louis. Four team members are Olympic gold medalists.

“Saint Louis Athletica is comprised of strong, smart, and extremely talented young women who are all at risk for breast cancer,” said Helen Chesnut, executive director of the St. Louis Affiliate of Susan G. Komen for the Cure®. “We couldn’t be more excited to have the team serve as honorary co-chairs of our Race and join us in finding the cures for breast cancer. Whether a daughter, sister, aunt or mother, these young women have either been touched in some manner by the disease, or will be in her life- time, and together we can make an impact.”

TEAM INFORMATION Team: Saint Louis Athletica Location: The Anheuser-Busch Soccer Park Tickets: 1-888-STL-GOAL Web site: www.saintlouisathletica.com

Some team facts: Four Olympic Gold Medalists are on the roster. Nine International Stars England’s Best Goalscorer, Eniola Aluko Japan’s Best Player, Aya Miyama World’s Best Goalkeeper, Hope Solo

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Milestones

How the Susan G. Komen St. Louis Race for the Cure® has grown:

1999 2000 2001 2002 2003 2004 2005 2006 2007

Net Proceeds $309,000 $665,000 $948,000 $1,200,000 $1,400,000 $1,600,000 $2,200,000 $2,400,000 $2,600,000

Participants 10,257 17,503 31,563 45,749 48,878 50,869 61,660 64,585 66,762

Survivors 545 805 1,682 2,414 2,750 2,850 3,833 3,947 4,117

Teams 25 100+ 210 450 501 505 754 763 886

Honorary Stephanie & D’Marco & Kurt & Kurt & Jackie The Buck Jason Steven Manny and Co-Chairs Scott Cynthia Farr Brenda Brenda Joyner Family & Lorrie Jackson & Gigi Legace Komen Warner Warner Kersee Isringhausen his mother, & Matt and Brenda Heather Jackson Morris 2008 2009

Net Proceeds $3,300,000 $3,250,000

Participants 64,007 66,470

Survivors 4,534 4,007

Teams 1,007 1,030

Honorary *Honorary Hoda Kotb Co-Chairs Co-Chairs of and the last 10 years Women on News Channel 5

*Honorary Chairs included: D’Marco Farr, Jason and Lorrie Isringhausen, Steven Jackson, Scott & Marnie Komen, Manny & GiGi Legace and Kurt & Brenda Warner.

The Komen St. Louis Race for the Cure hit the ground running in 1999 – the first St. Louis Race immediately earned the distinction of being the largest road race ever held in the city.

The inaugural year, there were 10,257 St. Louis Race participants that set and still hold a Komen record as the largest first-year event of any Race around the globe.

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Local Presenting Sponsor

Platinum Sponsors

Gold Sponsors Silver Sponsors Bronze Sponsors Anthem Blue Cross Blue Shield Best Buy CBL Properties CIGNA David C. Pratt Cancer Center Denny’s Edward Jones Lumière Place Casino and Hotels Dowd Bennett LLP Express Scripts Foundation Macy’s Foundation Emerson Motor Technologies Schnuck Markets, Inc. McCarthy Building Companies, Inc. Glory Foods St. Louis Magazine River City Casino Metro Wehrenberg Theatres SchoolReach Regions Bank St. Louis Cancer & Breast Institute SSM Cancer Care The Breast HealthCare Center at Missouri Baptist The Printing Source

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Wells Fargo Advisors Investing In Our Communities

Through dedicated volunteer efforts, philanthropy and community involvement in St. Louis and across the United States, Wells Fargo Advisors is committed to building strong and vibrant communities, improving the quality of life, and making a positive difference in the communities where our team members live and serve. Last year, Wells Fargo Advisors and its team members provided more than $9 million in sponsorships and grants to non-profit organizations as well as more than 80,000 hours in volunteer service to the community.

The Susan G. Komen St. Louis Race for the Cure® is the largest Komen Race for the Cure in the nation, and in 2009, with nearly 2,000 participants; Wells Fargo Advisors fielded the largest corporate team in St. Louis, raising nearly $200,000 to support the search for a cure. This enthusiasm reflects a long legacy of service and connection to the community, which in this case, began at the grassroots of the organization, led by employees who were committed to the cause and who felt and understood the impact personally. In 2010, Wells Fargo Advisors is again honored to be the presenting sponsor of the event and to play a visible and active role in helping to find a cure.

Wells Fargo Advisors’ community focus centers on education, civic leadership, arts & culture and human services including the Susan G. Komen St. Louis Race for the Cure®.

Education Human Services Investing in our future workforce through Providing food, shelter and access to quality programs that help provide quality teachers, healthcare to those who need it most. after school programs, college access and helping all to make sound financial choices. Investing In Our Communities Campaign In 2009 our firm developed 241 partnerships Big Brothers Big Sisters with basic needs organizations and supported Lending IT support and board leadership to them with $1 million in funding and 5,700 one of the nation’s most innovative chapters. volunteers. Our 2010 goal is to recruit 100 Wells Fargo Advisors team members to be new BBBS Susan G. Komen St. Louis Race for the Cure® mentors. Largest corporate team in the nation’s biggest race, raising nearly $200,000 to support the Financial Literacy search for a cure in 2009. Leveraging our financial experience by sharing the keys to economic success with Matching Gifts Campaign people of all ages. $2.02 million contributed to organizations with the help of 2,964 team members in 2009.

Civic Leadership Arts & Culture Supporting strong communities by investing in Ensuring that everyone has access to the arts diversity, leadership and citizen engagement. and the inspiration and understanding they provide. Nonprofit Assistance Helping nonprofits to fulfill their missions with Arts and Education funding, volunteer support and use of our Providing financial and volunteer support to campus space for local training and other enhance learning through partnerships with purposes. local arts organizations.

Diversity Through our words and our actions, showing the value and importance of every person in our firm and our communities.

Data is a combination of Wells Fargo Advisors, LLC, Wells Fargo Advisors Financial Network, LLC and First Clearing, LLC and is current as of April 8, 2010. Wells Fargo Advisors is the trade name used by two separate registered broker-dealers: Wells Fargo Advisors, LLC and Wells Fargo Advisors Financial Network, LLC, Members SIPC, non-bank affiliates of Wells Fargo & Company. First Clearing, LLC is a registered broker-dealer and non-bank affiliate of Wells Fargo & Company.

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Breast Cancer Facts

• A woman is diagnosed with breast cancer every three minutes in the U.S. and one woman will die of breast cancer every 13 minutes in the U.S. • An estimated 192,370 women will be diagnosed with breast cancer this year and an estimated 40,170 will die. • Except for skin cancers, breast cancer is the most frequently diagnosed cancer among women. • Breast cancer is second only to lung cancer in cancer deaths among women. • Aging and being female are the two biggest risk factors. • The majority of women with breast cancer have no known significant family history or other known risk factors. • Currently, there are about 2.5 million breast cancer survivors alive in the U.S. today.

Breast Cancer Globally

• Breast cancer is the most frequently diagnosed cancer and is the leading cause of cancer deaths among women worldwide. • In the past 25 years, incidence rates have risen approximately 30 percent in westernized countries. This increase may be due to changes in reproductive patterns and increased screening. • Someone dies from breast cancer every 68 seconds. • Mortality rates have been stable or decreasing in some countries. This reduction in developed countries is attributed to early detection through mammography and improved treatment.

Take the 20-10 Challenge!

If every Race Participant raised $200 ~ just by asking 20 friends for $10 ~ St. Louis would raise more than $13 million to help find the cures for breast cancer! It’s easy! By e-mail, by phone, or in person .... ask 20 friends for a $10 pledge and you will be well on your way to meeting the 20-10 Challenge!!

• Five Race registrations can pay for one free mammogram.

• $10 can buy a car voucher for a woman to travel to a doctor’s appointment.

• $25 can pay for one night’s lodging for an out-of-town patient.

• $50 can buy 100 brochures that help co-survivors cope with breast cancer.

• $75 can pay for a screening ultrasound or 250 breast self examination instruction cards.

• $90 can pay for a physician/consultation for a woman with an abnormal mammogram.

• $100 can pay for a screening mammogram.

• $150 can pay for a digital mammogram.

• $200 can buy a wig for a woman who loses her hair during treatment.

• $250 can buy a breast prosthesis for a woman who has lost her breast to cancer.

• $500+ can offset the costs of surgery, treatment and recovery for those diagnosed with breast cancer.

*Services for an uninsured or underinsured woman.

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About the St. Louis Affiliate of Susan G. Komen for the Cure®

The St. Louis Affiliate of Susan G. Komen for the Cure® was formed in 1999 shortly after the first Susan G. Komen St. Louis Race for the Cure. Today, the Komen St. Louis Affiliate is one of more than 125 Affiliates in the world.

The Affiliate is working to better the lives of those facing breast cancer in the local community joining more than one million breast cancer survivors and activists around the globe as part of the world’s largest and most progressive grassroots network fight- ing breast cancer.

Through events like the Komen St. Louis Race for the Cure, the Komen St. Louis Affiliate has raised more than $19 million in the fight against breast cancer, of which more than $13 million has gone to fund screening, treatment, education and research programs in community breast health programs in the 17-county service area in Missouri and Illinois. Additionally, the remaining $6 million has funded the national Susan G. Komen for the Cure® Grants Program for research.

Up to 75 percent of net proceeds generated by the Affiliate stay in the St. Louis area. The remaining income goes to the national grants program.

Call 314-569-3900 or visit www.komenstlouis.org for more information.

Komen St. Louis Affiliate

Board of Directors Daniel Bindler Our Promise Mikki Brewster ... to save lives and end breast Kenita Collier Renee Ribble Hall, President cancer forever by empowering Dede Hoffmann people, ensuring quality care for all Jennifer Kingston Paul Lovell, Treasurer and energizing science to find the Patrick Morgan Peter Ruger cures. Joan Sehl, Secretary Rachel Walker Kate Wall

Staff Executive Director ...... Helen Chesnut Affiliate Coordinator ...... Kathy McMillan Director, Grants & Mission Initiatives...... Jeremy Patch Director, PR and Marketing ...... Erica Stelling Director, Fund Development ...... Allison Tonsing Communications Intern...... Elaine Randant

Committee Chairs Public Policy...... Patrick Morgan Grants...... Kate Wall Race for the Cure...... Jen Kingston & Stacy Kingston Dine Out for the Cure...... Dawna Currigan Research Advocacy...... Lorry Blath & Judy Johnson

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St. Louis Affiliate of Susan G. Komen for the Cure® 2010 Grant Awards

The St. Louis Affiliate of Susan G. Komen for the Cure, along with those who generously support us with their time, talent, and treasures, is working to better the lives of those facing breast cancer in the St. Louis community. As a result of the Komen St. Louis Affiliate fundraising efforts, including the annual Susan G. Komen St. Louis Race for the Cure®, locally presented by Wells Fargo Advisors, more than $13 million in the last 11 years has been invested in the St. Louis community for breast cancer screening, treatment, education and support programs as well as research.

The Affiliate is proud to announce total grants of more than $3.5 million this year, a record amount for the Affiliate. More than $2.8 million will stay in the St. Louis community to fund 29 programs at local health care facilities and non-profits. These grants will go towards innovative projects in the areas of breast health and breast cancer research, education, outreach, screening, treatment and support services not otherwise available to the medically underserved populations of our 17-county service area.

In addition to the $2.8 million in local grants, more than $900,000 raised locally went to the Susan G. Komen for the Cure® Grants Program to fund superior-ranked breast cancer research programs. Below is a list of the 2010-2011 Komen St. Louis Affiliate Grant Recipients.

The Breakfast Club’s Bra and Prosthesis Program The Breakfast Club, Inc. Sherrill Jackson, BCI Founder and President, (314) 972-8883 http://www.breakfastclub-stl.org/ This is the 10th year of Komen St. Louis Affiliate funding for this program. The Breakfast Club Inc. is a breast cancer support group serving primarily African American uninsured and underinsured low income women residing in North St. Louis City and North St. Louis County by providing education, awareness, resources and support. The Breakfast Club is receiving funding to expand the Bra and Prosthesis Program for low-income and uninsured women. Komen St. Louis funding will provide 300 mastectomy bras and 100 breast prostheses for uninsured and underserved women in the St. Louis community.

Breast Cancer Screening and Education Program St. John’s Mercy Medical Center Carol Murphy, LCSW, (314) 251-6400 http://www.stjohnsmercy.org/services/breastcenter/default.asp This is the 8th year of Komen St. Louis Affiliate funding for this program. St. John’s Mercy Medical Center is the second largest healthcare provider in the St. Louis area and is committed to providing breast health services to uninsured and underinsured women. The breast screening and education program plans to provide approximately 765 breast exams and mammograms to low income women this year. The program relies on relationships between area health and social service agencies, Mercy Neighborhood Ministry and St. John’s Mercy Hospital in Washington. These agencies work to identify and reach out to low income women in need of routine breast screening services. The goal is to increase access to breast screening services, education, prevention and early detection of breast cancer. Every screening includes a breast exam, mammogram and education on how to do a breast exam and the importance of knowing how to identify a breast abnormality. Follow-up services are provided to every woman who requires additional diagnostic services.

Breast Health Nurse Navigator St. John’s-Washington Connie Stelzer, RN, Project Director, (636) 239-8697 http://www.stjohnsmercy.org/sjmh/default.asp This is the 2nd year of Komen St. Louis Affiliate funding for this program. St. John’s Mercy Hospital is the largest hospital in Franklin County offering Comprehensive Medical Surgical Care. The David C. Pratt Cancer Center at St John’s Mercy Hospital was opened November 2009 and offers a

www.komenstlouis.org | Raceline 314-569-3903 12th Annual Susan G. Komen St. Louis Race for the Cure® locally presented by Wells Fargo Advisors Saturday, June 12, 2010 - Downtown St. Louis full spectrum of diagnostic testing, innovative treatments and services for all types of cancer, including breast cancer. Located 50 miles southwest of St. Louis, St. John’s Mercy Hospital is committed to the quality healthcare for the residents of Franklin, St. Charles, Warren, Washington, and Jefferson Counties. A Breast Health Nurse Navigator maintains close contact with low income women who are diagnosed with breast cancer, helping them through the maze of healthcare. The Breast Health Nurse Navigator duties include: facilitating tests, consultations, treatment, finding supportive services and maintaining contact throughout treatment. The goal is to increase patient compliance with treatment plans, promote satisfaction with our services and to decrease wait times between diagnosis and treatment in order to improve quality of life and survival. It is expected that at least 100 women will receive assistance during the grant year as a result of Komen funding.

Bridging the Gap Emergency Breast Cancer Fund Saint Louis University, Department of Internal Medicine Rebecca Dougherty, MSW, LCSW, Project Director, (314) 268-7020 http://www.slu.edu/cancer-center.xml This is the 2nd year of Komen St. Louis Affiliate funding for this program. Many people with breast cancer face unexpected medical expenses and are not able to work during the course of treatment, adding a huge financial toll to their already difficult struggle. Bridging the Gap Emergency Breast Cancer Fund seeks to lessen the burden on people with breast cancer by providing emergency short-term financial assistance to those in need to help cover household bills and living expenses. Not worrying about unpaid bills will help recipients to better focus on treatment, healing, and recovery. Bridging the Gap recipients will be referred by a healthcare professional to the program to receive financial assistance with such things as rent, utilities, car expenses, insurance bills, etc. Potential recipients will be screened by the program manager to ensure they meet the program requirements. Eligibility criteria will include residency in one of the 17 counties served by the Komen St. Louis Affiliate, current income at or below 350% of the Federal Poverty Level, and being within a three-month window of receiving active breast cancer treatment (defined as surgery, radiation therapy and/or chemotherapy, excluding long-term hormone therapy). The program hopes to assist 180 breast cancer patients this grant year.

A Comprehensive Breast Health Awareness & Screening Program for Women in Rural Communities Jefferson Regional Medical Center Susie Thompson, Breast Health Center (636) 933-1686 http://www.jhsmo.com/ This is the 7th year of Komen St. Louis Affiliate funding for this program. Jefferson Regional Medical Center will provide a breast healthcare awareness and diagnostic screening program for uninsured/underinsured women in five rural counties (Jefferson, Ste. Genevieve, St. Francois, Washington and northern Perry). This program has three components: (1) comprehensive breast cancer education; (2) screening/diagnostic mammograms and ultrasounds; (3) support services. A breast nurse navigator will coordinate, deliver, monitor services using evidenced-based practices, evaluate outcomes and disseminate program results. This project will offer access to breast healthcare by providing comprehensive, quality breast health education, imaging and support services to the targeted population.

The Daylight Program of the Barnes-Jewish Hospital Refugee Health Service Barnes-Jewish Hospital Eva Enoch, Daylight Project Outreach Coordinator, (314) 747-5688 http://www.bjc.org/ This is the 8th year of Komen St. Louis Affiliate funding for this program. The Daylight Project is a multidisciplinary effort of the Barnes-Jewish Hospital Refugee Health Service. The program de- livers linguistically and culturally appropriate education about breast health promotion and the benefits of early detection of breast cancer. It links refugee/immigrant women with mammography screening and bilingual navigation assistance to the diagnostic services and treatment environments of the BJH Siteman Cancer Center. This mission is accomplished by a coordinator who works with key community agencies to provide education, access, and navigation for women needing screening or receiving diagnostic services or treatment for breast cancer. A community health worker provides translated materials and training in industries and agencies where new arrival women work and gather.

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Early Detection of Breast Cancer in African American Women Community Health-In-Partnership Services (CHIPS) Judy Bentley, WHNPBC, MA, President and CEO, (314) 652-9231 ext. 19 http://www.chipsstl.org/ This is the 2nd year of Komen St. Louis Affiliate funding for this program. While African American women are less likely to develop breast cancer than Caucasian women, African American women are much more likely to die from the disease. CHIPS’ Early Detection of Breast Cancer in African American Women Program addresses this disparity in the St. Louis Metropolitan Area. CHIPS seeks to improve breast cancer outcomes for uninsured African American women between the ages of 40 and 64 by promoting breast health self-awareness and the importance of early detection. CHIPS will provide one on one instruction, educational materials and referrals to 1,300 women during the funding period and will arrange for women who have not had a mammogram in a year or more to be screened. A mammography van visits CHIPS six times a year to provide free screenings. CHIPS operates a free clinic in North St. Louis staffed by volunteer physicians who care for uninsured and underserved clients from all over the metropolitan area. CHIPS also takes health screenings to at-risk individuals in the community at over 100 outreach and health education events each year.

East St. Louis Breast Cancer Screening & Treatment Southern Illinois Healthcare Foundation Beth Zurliene, RN, Project Director, (618) 482-7126 http://www.khrh.org/ This is the 3rd year of Komen St. Louis Affiliate funding for this program. Southern Illinois Healthcare Foundation is a Federally Qualified Health Center that operates 32 primary health care clinics. It is the primary health care provider to poor and uninsured individuals in the Metro East area. Komen funding will support two Patient Care Navigators to work on Southern Illinois Health Care Foundation’s START NOW! Breast Cancer Screening Program. Seven hundred and fifty patients will be guided through the screening, diagnostic and treatment processes, including getting help and reminders for setting up appointments, assistance with transportation when needed, and help filling out paperwork to qualify for services paid for by the Illinois Breast and Cervical Cancer Program (IBCCP), Medicaid, or other insurers.

Educating Women About Hereditary Risk for Developing Breast Cancer Saint Louis University, Department of Internal Medicine Suzanne Mahon, RN, DNSc, AOCN, APNG, (314) 577-8854 http://www.slu.edu/cancer-center.xml This is the 9th year of Komen St. Louis Affiliate funding for this program. An estimated 10% of women diagnosed with breast cancer have a hereditary predisposition and are at substantial risk for a second breast cancer; 50% of their first degree relatives also carry a very high risk (92%) for developing early onset breast cancer. The established Hereditary Cancer Program at Saint Louis University provides comprehensive education and counseling regarding the potential risks, benefits, and psychosocial ramifications of genetic testing as well as recommendations to detect cancer early, and prevent cancer by using appropriate strategies including prophylactic surgery. A trained genetics professional ascertains there is a comprehensive assessment of risk, the correct test is ordered, and provides coordination of follow-up care for other at-risk relatives. For families in which a specific genetic mutation cannot be identified the program assists in enrollment in clinical trials that will ultimately advance the science of genetics.This request is to continue to improve and expand the existing Hereditary Cancer Program by providing education and counseling to 90 new at-risk families and continuing to provide services to an estimated 75 established families. A series of community programs and personal meetings with health care providers will inform a wider sector about cancer genetic risk and the availability of services.

Empower and Engage SSM St. Mary’s Health Center Foundation Sandy Cobb, RN, Director, (314)768-8696 http://www.ssmhc.com/ This is the 9th year of Komen St. Louis Affiliate funding for this program. The Empower and Engage Program will continue to provide free breast health services for qualified women including screening and diagnostic mammograms, ultrasound and breast healthcare education,

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and coordination of services and treatment. SSM St. Mary’s Breast Center’s half-time RN Clinical Coordinator is dedicated to the recruitment of underserved women and to coordinating services for those women both in the Empower and Engage Program and Show Me Healthy Women (SMHW) Program. Empower and Engage will serve 200 women during the grant year by conducting 12 recruitment events, along with accepting walk-ins to the SSM Breast Center at St. Mary’s Health Center. The Breast Center will also enlist the services of collaborating programs and organizations, in order to provide exceptional healthcare with a full range of services.

FCHC Breast Health Screening Access Project Family Care Health Centers Kathleen Garst, Chief Operations Officer, (314) 481-1615 ext. 1314 http://www.fchcstl.org/ This is the 2nd year of Komen St. Louis Affiliate funding for this program. Upon initiation of a navigator program, FCHC has been able to implement evidence-based techniques that increase mammography opportunities for our patients as well as guide them through the screening process. With continued collaboration with Siteman Cancer Center, FCHC will continue to promote patient education and awareness of initial mammogram screenings and expedite follow-up appointments. FCHC plans to increase capacity to 900 mammograms.

Gateway to Hope Gateway to Hope Cynthia Frank, Executive Director, (314) 569-1113 http://www.gthstl.org/ This is the 6th year of Komen St. Louis Affiliate funding for this program. Gateway to Hope (GTH) arranges comprehensive medical and surgical treatment for uninsured and underinsured low income women and men diagnosed with breast cancer and those genetically at high risk for breast cancer. These individuals earn between 200-350% of federal poverty guidelines and are not eligible for publicly funded medical programs. GTH will arrange breast cancer treatment for a minimum of 30 eligible patients and will continue to arrange treatment for approximately 25 individuals already in the program. Additionally, a minimum of 80 referrals will be made to healthcare providers or social service agencies to help individuals not eligible for GTH services. This project supports the work of two nurse managers who arrange treatment for GTH patients and one outreach education nurse.

Iniciativa de Salud para Mujeres (Women’s Health Initiative) Puentes de Esperanza Nereida Avendano, Project Director, (618) 398-0557 http://www.hoyleton.org/ This is the 3rd year of Komen St. Louis Affiliate funding for this program. Puentes de Esperanza (Bridges of Hope) is a faith-based organization whose mission is to enhance the quality of life within a growing Metro East Hispanic/Latino community. Due to language, cultural, social, and economic barriers, Hispanic and Latino women are typically screened for breast cancer later than other women, resulting in lower survival rates. Lack of proper identification and/or legal documentation of immigration status, exacerbates the problem. Through an intense, culturally sensitive outreach effort, this program seeks to eliminate these barriers and increase breast cancer awareness. Komen funding will provide breast cancer related information and services to 300 women during the grant period.

Lymphedema Assistance Program St. Louis Peregrine Society, Inc. Shari Cunningham, Events Coordinator, (314) 781-6775 http://www.peregrinesoc.org/ This is the 5th year of Komen St. Louis Affiliate funding for this program. The St. Louis Peregrine Society instituted the Lymphedema Assistance Program to help breast cancer survivors control and minimize the pain associated with lymphedema. The program is available to uninsured and underinsured women as a resource for obtaining the garments necessary to control the pain and swelling associated with treatment of breast cancer. Each patient enrolled is eligible to receive compression garments and replacements as recommended by their health care professional. As a result of the funding this program has been able to help hundreds of women suffering from lymphedema. With Komen funding, the Peregrine Society expects to provide 120 lymphedema garment sets for uninsured and underinsured women in the St. Louis area.

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The MBMC Breast HealthCare Center Reaching the Underserved Missouri Baptist Medical Center Sarah Ernsky, RN, BSN, Manager, Breast HealthCare Center, (314) 996-7554 Theresa Taylor, Breast HealthCare Outreach Coordinator, (314) 996-7585 http://www.breasthealthcarecenter.org/ This is the 9th year of Komen St. Louis Affiliate funding for this program. The Breast HealthCare Center at Missouri Baptist Medical Center continues to be a strong leader with its commitment to reach out to uninsured and under-insured women. With Komen funding, they are able to provide increased access to breast screening services as well as education, prevention, and early detection of breast cancer by providing screening and diagnostic mammograms. These services are provided in the Breast HealthCare Center and on the digital mobile mammography van for at risk women ages 40 - 64. Follow up services are provided at the Breast HealthCare Center for women with mammography abnormalities. The educational component provides knowledge about the importance of early detection of breast cancer by screening and the dynamics of breast self-exam. These educational events are held in the service areas of St. Louis City and County along with eleven rural communities which include: Jefferson, St. Francois, Warren, Ste. Genevieve, Perry, Lincoln, Madison, Washington, Franklin, St. Charles, and Montgomery County. The proven success of this project has demonstrated that women in these service areas desire to utilize resources to gain information on breast health and undergo a screening procedure on our van. With Komen funding, Missouri Baptist plans to educate and screen over 600 women in the current grant year.

The Navigator Project Washington University School of Medicine Vickie Knighten, Breast Cancer Patient Navigator, (314) 362-3195 http://www.siteman.wustl.edu/ This is the 7th year of Komen St. Louis Affiliate funding for this program. The Breast Cancer Patient Navigator Program provides support to medically underserved women in the St Louis area who are treated for breast cancer at Siteman Cancer Center. The goals of the program are to decrease the time from a biopsy showing breast cancer to initiation of treatment by providing counseling, practical support and removing barriers to care. The program supports delivery of culturally sensitive breast cancer care at SCC. The program addresses problems experienced by the target population that affect their ability to receive or complete treatment of breast cancer. Services are provided by a Breast Cancer Patient Navigator who works with all oncology service areas. The navigator assists with transportation needs, scheduling, escort to tests or procedures, completing paperwork and referral to community support agencies and services.

Navigating the Safety Net: Paving Smooth Pathways to Care for Underserved People Barnes-Jewish Hospital Susan Kraenzle, RN, Joanne Knight Breast Health Center, (314) 454-7620 http://www.siteman.wustl.edu/ This is the 11th year of Komen St. Louis Affiliate funding for this program. This program will care for more than 2,600 underserved, low income people in all counties served by the Komen St. Louis Affiliate. It will provide services along the complete trajectory of breast care, from outreach and screening through follow- up, diagnosis, and treatment. To overcome barriers to access, a mobile mammography unit, equipped with full-field digital technology, travels throughout the area. Screening is also provided at the Siteman Cancer Center’s Breast Health Center, to which many patients are referred for diagnostic follow up and care. Intensive outreach efforts at both the grassroots and stakeholder levels and 12 educational events throughout the year will motivate patients to accept breast health services. Our three diagnostic navigators will accompany 650 patients along the continuum from a suspicious finding through diagnostic work up, biopsy, and final resolution.

www.komenstlouis.org | Raceline 314-569-3903 12th Annual Susan G. Komen St. Louis Race for the Cure® locally presented by Wells Fargo Advisors Saturday, June 12, 2010 - Downtown St. Louis

Nutritional Support for Low Income Breast Cancer Patients Food Outreach, Inc. Greg Lukeman, Executive Director, (314) 652-3663 ext. 115 http://www.foodoutreach.org/ This is the 4th year of Komen St. Louis Affiliate funding for this program. Food Outreach’s Breast Cancer Program provides comprehensive nutritional support to low-income breast cancer patients through a combination of scratch-made nutritious meals, groceries, and nutrition education. Many are ineligible for senior meals programs and due to the nature of the illness and treatments require a tailored nutrition program, not available through traditional food pantries. Our on-staff Chef and Registered Dietitian develop menus targeting our clients’ specific nutrition needs to help them maintain strength, cope with side effects and have better treatment outcomes. Each client meets with our Dietitian for an initial nutritional assessment. The Dietitian recommends an eating plan taking into consideration the assessment results, treatments and side effects, and any secondary illnesses. Our Dietitian provides follow-up nutrition status assessments, and with approval, forwards results to the client’s healthcare team for continuum of care. Every two weeks, clients order the equivalent of two meals per day from a changing menu (up to 28 meals per order). Choosing their own meals/groceries is significant, since taste changes are prevalent throughout treatment. Our scratch-made meals are frozen in microwaveable containers – ensuring convenient access to healthful meals when clients are too fatigued to fully prepare a meal. Food Outreach also provides a meal home delivery program.

Outreach, Education, and Screening in Madison County, Illinois Madison County Health Department Amy Yeager, MPH, Health Promotion Services, (618) 692-7040 ext. 6087 http://www.madisoncountyhealthdepartment.org/ This is the 8th year of Komen St. Louis Affiliate funding for this program. The Outreach, Education, and Screening program of the Madison County Health Department helps women by addressing breast cancer awareness and screening. The first part of the project focuses on outreach and education to help women become more aware of the importance of screening for breast health and the availability of services to motivate them to seek screening. Education will be provided through social marketing campaigns, community events, lunch and learn presentations, and dissemination of information to the community. Outreach efforts will use media, presentations, door-to- door campaigns, and community groups and health care providers to help reach women who qualify for screening. The second part of the project will provide 120 mammograms to uninsured and underserved women between the ages of 40- 64, 10 diagnostic mammograms, 10 ultrasounds, and 50 office visits.

People’s Sister Connection Betty Jean Kerr People’s Health Centers Mark Sanford, VP, Planning & Development, (314) 367-7848 ext. 1209 http://www.phcenters.org/ This is the 8th year of Komen St. Louis Affiliate funding for this program. The “Sister Connection Program” is utilizing a Patient Navigator Model to reach our target population of 2,439 medically underserved and uninsured women to encourage them to get clinical breast exams and mammograms. As part of the visits women receive educational information regarding breast health screenings. A part-time mammographer will be hired at our North St. Louis County location which will increase access to breast screening services, diagnostic follow-up and treatment. The navigator is readily available to accompany the women who are fearful of getting their mammograms, and when schedules permit the clinical breast exams and mammograms can be done in one visit. The patient navigator will help to reduce all barriers to care and will continue to promote clinical breast exams and mammograms internally with providers by conducting in-services. PHC will implement mammography services at the north county location and is projecting 600 mammograms will be provided for women ages 40 to 49.

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Reaching In: A Comprehensive Program for Breast Screening Saint Louis University Mark Varvares, MD, Director, Saint Louis University Cancer Center, (314) 268-7053 http://www.slu.edu/cancer-center.xml This is the 2nd year of Komen St. Louis Affiliate funding for this program. Saint Louis University (SLU) Cancer Center is expanding its Breast Cancer Screening Program. Komen St. Louis Affiliate funding will provide a nurse navigator to assist underserved/uninsured or underinsured, low income women ages 40- 65 in St. Louis through a complex healthcare system to obtain necessary and regular breast cancer screening. The St. Louis area consists of a diverse population with significant psychosocial, logistical and physical issues impeding them from getting needed care. A nurse navigator acts as an accessible contact for each woman, offering continuity of care, coordination of services, education and psychosocial support throughout the care continuum. SLU is focusing in-reach efforts to provide breast health care to underserved, at-risk women who are currently receiving tertiary care at SLU, as well as family members, friends and support employees at the University that are uninsured or underinsured. SLU Cancer Center has expanded its community outreach efforts including participation at local health fairs, educational symposiums and community events to educate and provide referrals for services for at risk persons. SLU estimates that 600 women will be served through this Komen-funded partnership.

Rural Missouri Outreach Project East Missouri Action Agency Angel Prather, Program Director, (573) 431-5191 ext.1122 http://www.eastmoaa.org/ This is the 1st year of Komen St. Louis Affiliate funding for this program. EMAA will help uninsured and underserved women in Jefferson, Madison, Perry, St. Francois, St. Genevieve, and Washington counties in Missouri. The work will be provided in cooperation with Missouri Baptist Breast Healthcare Mammogram Van, Washington County Hospital, Madison County Regional Hospital, and Jefferson Regional Medical Center. EMAA has discovered that many women-particularly those in rural areas- do not have the transportation readily available for them to take advantage of the mammogram van when it visits larger towns in their counties. Having the van visit smaller, more out-of-the-way communities will give women better access to services. The program plans to provide screening mammograms to at least 185 women.

Solutions for Women: Breast Health Education and Outreach for Underserved Women Christian Hospital Northeast-Northwest Sandi Kenkel, Manager, Radiation Oncology, (314) 653-4498 http://www.christianhospital.org/ This is the 3rd year of Komen St. Louis Affiliate funding for this program. Through this project women of North St. Louis County, who are not insured or are underinsured, will have the opportunity for screening, early diagnosis and treatment of breast cancer. For women over 40 years of age and those at high risk for breast cancer and not eligible for this service through other means they will qualify for a screening mammogram. If necessary, additional diagnostic testing will be provided. For the small number of women who need additional services, they will be provided referrals to the Show Me Healthy Women Program which is also provided at Christian Hospital through a State of Missouri Grant. Through the outreach coordinator, women will be educated on the importance of good breast health. Through education, women who are at average risk can learn how to reduce their risk of developing the disease by changing certain lifestyle factors. The outreach coordinator is available to provide educational programs for organizations as well as participate in health fairs stressing the importance of self exams and the need for yearly mammograms.

www.komenstlouis.org | Raceline 314-569-3903 12th Annual Susan G. Komen St. Louis Race for the Cure® locally presented by Wells Fargo Advisors Saturday, June 12, 2010 - Downtown St. Louis

SSM St. Joseph Breast Health Outreach Program SSM St. Joseph Foundation Terry Lohmeyer, RN, BS, (636) 947-5617 http://www.ssmhc.com/ This is the 8th year of Komen St. Louis Affiliate funding for this program. The SSM St. Joseph Breast Health Outreach Program serves uninsured and underinsured women aged 40 to 64 and those under 40 with symptoms or at high risk of breast cancer in St. Charles, Lincoln, Warren, and Montgomery counties. Program services include patient education regarding the risks of breast cancer and instruction in proper breast self exam. In addition, women receive a clinical breast exam and a screening or diagnostic mammogram, necessary biopsies and any follow-up care needed. All services are available at any of our four SSM facilities in St. Charles County: St. Joseph Health Center, St. Joseph Medical Park, St. Joseph Hospital West, and St. Joseph Wentzville. SSM St. Joseph anticipates serving a total of 390 women, of which 215 women will be eligible through Komen-funded services.

STEP-UP Grace Hill Grace Hill Neighborhood Health Centers, Inc. Veronica Richardson, Director, Community Health Services, (314) 814-8698 http://www.gracehill.org/ This is the 3rd year of Komen St. Louis Affiliate funding for this program. Grace Hill Neighborhood Health Centers, Inc. will endeavor to aggressively address the high incidence of mortality from breast cancer that disproportionately affects minority women living in the Grace Hill service areas. Grace Hill will strive to increase the rate of early detection of breast cancer by expanding the in-reach and education efforts targeted to over 8,700 of its current female patients, as well as over 2,000 additional women in the community. Funding will be used to address system changes, including allocating a provider to clinical breast exams for “Mammogram Days.” By increasing staff knowledge and skill in addressing cultural barriers among the ethnically diverse patient population, Grace Hill is able to provide education and support services utilizing culturally competent peer health coaches. These efforts will result in more than 1,000 women receiving clinical breast exams and screening mammography services in the grant year.

Wellness for Women St. Clair County Health Department Karen Pratt, Outreach & Prevention Manager, (618) 233-7703 http://www.health.co.st-clair.il.us/ This is the 9th year of Komen St. Louis Affiliate funding for this program. The Wellness for Women Project is a Komen St. Louis Affiliate funded program of the St. Clair County Health Department that increases breast cancer awareness and screening to women in St. Clair County, Illinois. Komen funding will provide 200 screening mammograms for low-income uninsured women, aged 40-49, and low –income women with insurance who have a high deductible and cannot afford the cost of routine mammograms. The Wellness for Women project with the BCCP serves as a vital resource for both Southern Illinois Healthcare Foundation and Puentes de Esperanza (with Hispanic women), both Komen grantees in St. Clair County, Illinois, to assist women in accessing both state and federally funded health care programs. For women enrolled in BCCP, if breast cancer is diagnosed, staff will apply for a medical card through the Health and Family Services for Treatment Act funding through a BCCP collaborative agreement.

Women’s Information and Screening Endeavor (WISE) Program SSM St. Clare Health Center Foundation Sandy Cobb, RN, BSN, RDMS, Director, Women’s Imaging, (314) 768-8696 http://www.ssmhc.com/ This is the 2nd year of Komen St. Louis Affiliate funding for this program. The WISE Program of SSM St. Clare employs a Clinical Coordinator who recruits women living along the I-44 corridor of St. Louis and Franklin Counties and in Jefferson County for free mammography and breast health education. Once in the program, women receive additional support from a Breast Health Specialist who provides in-depth education, clinical breast exams, care coordination, and empowers women to be proactive about their breast health. The program plans to provide 120 Komen-funded mammograms.

www.komenstlouis.org | Raceline 314-569-3903 12th Annual Susan G. Komen St. Louis Race for the Cure® locally presented by Wells Fargo Advisors Saturday, June 12, 2010 - Downtown St. Louis

2010 CRAFT Grant Awards (funding Clinical Trials Research)

Breast Cancer Resource to Study Prevention in African American Women (SPAA) Washington University School of Medicine D. Craig Allred, MD, Professor of Pathology & Immunology The St. Louis Breast Tissue Registry in coordination with the Women’s Health Initiative will be creating a subset of breast cancer cases of African American Women. A Tissue Microarray will be created for biomarker studies from the existing 200+ cases in the St. Louis Breast Tissue Registry. This array, having all stages of cases (DCIS through stage IV) and treatment information as well as recurrence and outcome data, will be available to researchers at Washington University and the St. Louis Community. African American Women registered in the Women’s Health Initiative who develop breast cancer will also be entered into the St. Louis Breast Tissue Registry and tissue and data (pathological and outcome) will be made available to investigators as cases are diagnosed.

A Phase I/II Trial of Letrozole in Combination with MK2206 in Clinical Stage II or III Estrogen Receptor Positive and HER2 Negative Breast Cancer Washington University School of Medicine Cynthia X. Ma, MD, PhD, Assistant Professor of Medicine Endocrine therapy, such as letrozole, is a standard adjuvant therapy following surgical removal of Estrogen Receptor positive (ER+) breast cancer to prevent recurrence. However, the occurrence of a complete pathologic response, a marker of complete eradication of the cancer, is rare by using endocrine therapy because of its inability to induce cell death. As a result, a prolonged course of therapy after surgery is necessary and thus, strategies to improve the effectiveness of endocrine therapy are needed. We have recently demonstrated, in cell culture studies, that drugs inhibiting the essential cell survival pathway are capable of killing the cancer cells when combined with endocrine therapy.