TInC 2014 – Bioinorganic May 22 at Medicon Village, Lund

Programme

08.30‐09.00 Registration

09.00‐09.05 Welcome 09.05‐10.00 Artificial metalloenzymes: challenges and opportunities Thomas R Ward, Department of Chemistry, University of Basel, Switzerland http://www.chemie.unibas.ch/~ward/ 10.00‐10.30 Coffee break

10.30‐11.30 Combined experimental and theoretical studies on the active site of nitrogenase Frank Neese, Max‐Planck Institute for Chemical Energy Conversion, Germany www.cec.mpg.de/menschen/direktoren/frank‐neese/vita.html 11.30‐12.30 Photoactivated and organometallic anticancer complexes Peter Sadler, Department of Chemistry, University of Warwick, UK http://www2.warwick.ac.uk/fac/sci/chemistry/research/sadler/

12.30‐14.00 Lunch (Lunch may be purchased for 75 SEK at Medicon Village. There are also several other lunch restaurants in the immediate vicinity)

14.00‐15.00 /dioxygen Edward Solomon, Department of Chemistry, Stanford University, USA www.stanford.edu/group/solomon/home.html

15.00‐15.30 Coffee break

15.30‐16.30 Title to be announced Amy Rosenzweig, Department of Molecular Biosciences, , USA http://groups.molbiosci.northwestern.edu/rosenzweig/ 16.30‐17.30 The amazing high‐valent ‐oxo reaction landscape Lawrence Que, Department of Chemistry, University of Minnesota, USA http://bioinorg.chem.umn.edu/quespace/

17.30‐18.30 Poster session

18.30‐ Dinner (Optional in registration form for 375 SEK incl moms/VAT)

TInC 2014 – Bioinorganic Chemistry May 22 at Medicon Village, Lund

Poster Abstracts

NOTE! Please put your poster on the board with your poster number on. The poster number (PN) is the same as the page number in this document. List of Abstracts

Nr. Title Presenting Author 1. Synthesis and properties of new biomimetic [2Fe-2S] clusters Marie Bergner 2. Bulky N,N,O ligands in mononuclear non-Heme iron enzyme mimics Emma Folkertsma 3. Iron(II)- and oxoiron(IV)-tetracarbenes – reactivity towards small molecules and more Claudia Kupper 4. Electronics study on the hydroxo-bridged diiron(III) bisporphyrin systems Mala A. Sainna 5. Halogen-bonding stabilizes a Fe(III)-oxo transfer reagent adduct Christine J. McKenzie 6. Reactions of Rieske-type biomimetic [2Fe–2S] clusters with nitric oxide Christine Schiewer 7. New pyrazolate based diiron complexes for the activation of dioxygen and for water oxidation Anne Schober 8. Design and synthesis of bioinspired iron complexes with dinucleating polydentate ligand Albert A. Shteinman 9. Gas phase chemistry of [LFeO]+ complexes Simon Svane 10. From model complexes of Tyrosinase and its inhibited forms to the design and study of new inhibitors Elina Buitragoa 11. Mimicking copper mediated dioxygen activation with the assistance of BOX ligands: A switch from μ-η2:η2-peroxo to bis(μ-oxo) dicopper(II) core by virtue of a base Vandana E. Goswami 12. Dioxygen activation studies with a bio-inspired copper complex Nicole Kindermann 13. Hybrid QM/QM studies of molybdenum enzymes –Reaction pathways and potentials Milica Andrejić 14. Synthesis of pyrazine-pyrane-dithiolene ligands mimicing specific features of molybdopterin Claudia Schindler 15. Pyrazolbased ligand scaffolds provide second sphere hydrogen bonding: substrate coordination by bimetallic complexes Natascha Bruckner 16. Manganese complexes of monocarboxylato ligands as catalysts for epoxidation Claire Deville

17. Chromium(V)-oxo and chromium(IV)-O2 adducts derived from an unusually labile chromium(III) complex David P. De Sousa 18. Development of new vanadium (IV/V) catalysts with non-innocent ligands for the enantioselective oxidation of prochiral sulfides Lina Fischer 19. Photosystem II like water oxidation mechanism in a bioinspired tetranuclear manganese complex Rong-Zhen Liao 20. Thymol bromination: a comparison between enzymatic and chemical catalysis Federica Sabuzi 21. Insight into the reaction of novel ruthenium based water oxidation catalysts Thorsten Stolper 22. Crystals that breathe Jonas Sundberg 23. Fatty acid oxidizing enzymes in Lobosphera incise Benjamin Djian 24. Synthesis and application of modified and labelled lipids C. Hansen

25. Reversible conversion of formate and CO2 by formate dehydrogenase from Rhodobacter capsulatus Tobias Hartmann 26. Studies on the active site of E. coli TMAO reductase using a defined in vitro assay for the reconstitution of apo-TMAO reductase activity with bis-MGD Paul Kaufmann 27. Structural basis for the formation of a bis-allylic hydroperoxide by a cyanobacterial lipoxygenase Julia Newie 28. Combinatorial nucleotide deletion analysis of functional nucleic acids Katarzyna Wawrzyniak-Turek 29. Uptake of essential metal ions mediated by periplasmic binding proteins Ellis Wilde 30. Functional characterization of a dodecaheme c-type cytochrome involved in microbial electron transfer to energy production in MFCs Mónica N. Alves 31. Cytochrome P450 enzymes are valuable biocatalysts Viktoria Bruckhoff 32. Arsenic resistance and detection of arsenic reduction and oxidation abilities of bacterial strains isolated from contaminated soil Marek Chyc 33. Effect of selected types of soot on germination, growth and some physiological parameters of Arabidopsis thaliana Marek Chyc 34. DF-Click: a modular approach to the de novo design of catalysts M. Chino 35. Using modified zinc finger domains as selective DNA hydrolysis tool or fluorescence metal probe F. Czerny 36. Transition metal-binding G-quadruplexes David M. Engelhard 37. Rigid spin labels for studies of RNA secondary structures Anne Ochmann 38. Interfering with RNAi; a study of platination and abasic sites modifications of miR-146a Alak Alshiekh 39. Towards metal-mediated DNA nanostructures containing a trans-chelating ligand Fernanda A. Pereira 40. Specific interactions of synthetic metallopeptides with target DNA H. Rao 41. Modified nucleotides as fluorescent probes and for the investigation of the orotidine decarboxylase mechanism Julia Schneider 42. Tetrazole-based gold(I) complexes as a new group of anticancer agents Tatiyana Serebryanskaya 43. The chaperone FdsC for Rhodobacter capsulatus formate dehydrogenase binds the bis-molybdopterin guanine dinucleotide cofactor Nadine Böhmer 44. Bispidine iron(IV)-oxo complexes: kinetics and electronic properties Anna-Maria Rensland 45. A mononuclear iron(III)-peroxide that breaks strong C-H bonds with high reaction rates Joan Serrano