1 Introduction
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Clinical Pharmacology in the UK, C. 1950–2000: Industry and Regulation
CLINICAL PHARMACOLOGY IN THE UK, c. 1950–2000: INDUSTRY AND REGULATION The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 25 September 2007 Edited by L A Reynolds and E M Tansey Volume 34 2008 ©The Trustee of the Wellcome Trust, London, 2008 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2008 The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 085484 118 9 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as: Reynolds L A, Tansey E M. (eds) (2008) Clinical Pharmacology in the UK c.1950-2000: Industry and regulation. Wellcome Witnesses to Twentieth Century Medicine, vol. 34. London: Wellcome Trust Centre for the History of Medicine at UCL. CONTENTS Illustrations and credits v Abbreviations vii Witness Seminars: Meetings and publications; Acknowledgements E M Tansey and L A Reynolds ix Introduction Professor Parveen Kumar xxiii Transcript Edited by L A Reynolds and E M Tansey 1 References 73 Biographical notes 89 Glossary 103 Index 109 ILLUSTRATIONS AND CREDITS Figure 1 AstraZeneca Clinical Trials Unit, South Manchester. Reproduced by permission of AstraZeneca. 6 Figure 2 A summary of the organization of clinical trials. Adapted from www.clinicaltrials.gov/ct2/info/glossary (visited 1 May 2008). 10 Figure 3 Clinical trial certificates (CTC) and clinical trial exemption (CTX), 1972–1985. Adapted from Speirs (1983) and Speirs (1984). -
The Robert Jones & Agnes Hunt Orthopaedic & District Hospital NHS
The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust The Robert Jones & Agnes Hunt Orthopaedic Hospital Quality Report Twympath Lane Gobowen Oswestry Shropshire SY10 7AG Tel: 01691 404000 Date of inspection visit: 6 – 8 October 2015 Website: www.rjah.nhs.uk Date of publication: 03/03/2016 This report describes our judgement of the quality of care at this hospital. It is based on a combination of what we found when we inspected, information from our ‘Intelligent Monitoring’ system, and information given to us from patients, the public and other organisations. Ratings Overall rating for this hospital Requires improvement ––– Medical care Requires improvement ––– Surgery Good ––– Critical care Requires improvement ––– Services for children and young people Requires improvement ––– Outpatients and diagnostic imaging Requires improvement ––– 1 The Robert Jones & Agnes Hunt Orthopaedic Hospital Quality Report 03/03/2016 Summary of findings Letter from the Chief Inspector of Hospitals The Robert Jones & Agnes Hunt Orthopaedic Hospital is part of The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust. The hospital is one of the UK’s five specialist orthopaedic centres. It provides specialist and routine orthopaedic care to its local catchment area, and specialist services both regionally and nationally. We inspected this hospital in October 2015 as part of the comprehensive inspection programme. We inspected all of the core services provided by the hospital. We visited the hospital on 6, 7 and 8 October as part of our announced inspection. We also visited unannounced to the hospital on Thursday 15th October 2015. Overall we have rated this hospital as requires improvement. -
The Midland Spinal Injury Unit at the Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry
PARAPLEGIA lectures on specific problems in spinal lesions and rehabilitation. In the course of this programme we also train physiotherapists, occupational therapists and, above all, nursing staff. Refresher courses may take one to three days, while more comprehensive training courses take three to four months. Candidates for a doctor's degree are working in smaller groups when investigating special pro blems of paraplegia. Through scientific congresses and by advanced training courses for physicians and surgeons we are trying to collect and widen our experiences in this particular subject of medicine. We seek, as other specialists do, close co-operation with other branches of medicine which are involved in the treatment of paraplegics and tetraplegics. In order to achieve such a close relationship we are going to organise inter disciplinary lectures to stimulate the exchange of experiences with other branches of medicine. Another field of importance to which we give much attention is documenta tion and collecting of material dealing with rehabilitation as a special medical problem. In this respect we have established contact with other paraplegic units to pool experience on both medical and social problems. One day when discussing rehabilitation problems with a well-known professor and director of a large university hospital, he expressed concern that a rehabilitation centre for paraplegics of the size of the Heidelberg centre might, like a hydro cephalus, disturb the organisational equilibrium of a hospital. While I can understand his concern, I cannot accept this view at all. I believe that a rehabilita tion centre of this size may certainly become an important section of a large hospital and it may even become an integral part of the whole medical faculty of a university and may, by its initiative and work, exert a beneficial influence on other sections of the hospital and medical faculty as a whole. -
Chapter 4 ET Bellhouse Engineers
CHAPTER 4 E.T. BELLHOUSE AND CO. ENGINEERS AND IRON FOUNDERS Edward Taylor Bellhouse (1816 – 1881), eldest son of David Bellhouse junior (1792 – 1866), was one of the leading engineers in Manchester during the nineteenth century.1 He began work as an apprentice to Messrs. Wren and Bennett beginning in about 1830. This firm was one of the leading millwright-engineering concerns in Manchester, especially in the area of cotton factories. After six and a half years with Wren and Bennett, Edward Bellhouse worked for a year as a journeyman millwright at the Coloa Mills and at the St. Helens’ Union Plate Glass Works. Another year was spent at Sir William Fairbairn’s works in the Isle of Dogs, Millwall. His last year as an employee was spent working for the Liverpool Grand Junction Railway. Bellhouse’s grandfather intended that Edward take over the foundry. His education has every appearance of having been planned by his father, using the father’s connections with Fairbairn and the glass company, for example. The Bellhouses seem to have had a continuing professional relationship with William Fairbairn. In 1832, David Bellhouse and Son built the cabin and deck for the iron canal packet boat “The Lancashire Witch constructed by Fairbairn and Lillie.2 David Bellhouse junior and Fairbairn jointly reported on the fall of the mill at Oldham in 1845.3 That same year David Bell- house and Fairbairn were corresponding about the loading of cast iron beams.4 In 1854, when Edward Bellhouse constructed a prefabricated iron customhouse for the town of Payta in Peru, Fairbairn visited the building while it was on display in Manchester.5 Curiously, Edward Bell- house made no reference to his family’s professional connections with Fairbairn when Bellhouse read a paper, entitled “On Pole’s Life of the Late Sir William Fairbairn,” to the Manchester As- sociation of Employer, Foremen and Draughtsmen in 1878.6 The intentions of the grandfather were fulfilled on July 1, 1842, when the firm of E.T. -
2005 Iowa Orthopedic Journal
Designed for Wear Reduction • Improved Function • Optimal Kinematics4 VOLUME 25 2005 THERE IS A DIFFERENCE The Iowa Orthopaedic Journal DEPUY ROTATING PLATFORM KNEE 1 REDUCED WEAR BY 94% Polyethylene wear has been associated with osteolysis in the knee.2,3 * The rotating platform knee, used with GVF JOURNAL ORTHOPAEDIC THE IOWA polyethylene, reduced wear by 94% when compared to a fixed bearing knee. Results based on knee simulation testing. Available only from DePuy Orthopaedics. Trusted Innovation. 1 ASTM Symposium on Cross-linked Thermally Treated Ultra High Molecular Weight Polyethylene for Joint Replacements (data on file). Miami Beach, Florida Nov. 5 and 6, 2002. 2 Lewis, Peter; Cecil H. Rorabeck, Robert B. Bourne and Peter Devane. “Posteromedial Tibial Polyethylene Failure in Total Knee Replacements.” CORR Feb. 1994: 11-17. 3 Cadambi, Ajai, Gerard A. Engh, Kimberly A. Dwyer and Tuyethoa N. Vinh. “Osteolysis of the Distal Femur After Total Knee Arthroplasty.” The Journal of Arthroplasty Dec. 1994: 579-594. * GVF - Gamma Vacuum Foil IMPORTANT • The presence of osteomyelitis, pyrogenic infection or other overt infection of the These include: This Essential Product Information sheet does not include all of the information nec- knee joint; essary for selection and use of a device. Please see full labeling for all necessary infor- • Patients with loss of musculature or neuromuscular compromise leading to loss of •Vascular deficiency at the bone site; mation. function in the involved limb or in whom the requirements for its use would affect •Inadequate bone stock to assure both a firm press fit and close apposition of the cut recommended rehabilitation procedures. -
The Careers of Geoffrey Jefferson, Harry Platt and John Stopford, 1914–39
ACADEMIC MEDICINE IN MANCHESTER 133 Academic medicine in Manchester: the careers of Geoffrey Jefferson, Harry Platt and John Stopford, 1914–39 STELLA V. F. BUTLER* In October 1939 John Stopford,Vice Chancellor of the University of Manchester, noted in his Annual Report that two new Chairs had been created in the Medical Faculty during the previous academic year.1 Harry Platt had become Professor of Orthopaedic Surgery, and Geoffrey Jefferson Professor of Neurosurgery. Both Chairs were grouped within a new Department of Surgery under the directorship of John Morley. Neither Platt nor Jefferson received any pay related to these posts. However, financial reward was of little significance within these appointments. Rather, the Chairs conferred status upon both for their contributions to surgery as specialist surgeons and so underlined the increasing differentiation of medical practice. The development of surgical specialisms during the 1910s and 1920s had been resisted by many within the profession.2 Platt and Jefferson had been risking much, therefore, when they confined themselves to relatively narrow clinical fields as soon as they were able after qualifying in 1909. Yet both were eventually fêted by their peers: Platt as President of the Royal College of Surgeons; Jefferson as a Fellow of the Royal Society.Their careers were inter-twined from the moment they met as students in *This paper forms part of a broader study of the career of Sir Harry Platt, Bart. I am grateful to Elizabeth Gow for her magnificent catalogue of the Platt Papers, completed as part of the Manchester Archives Project funded by the Wellcome Fund for Research Resources in Medical History. -
A Tribute to the Midlands Centre for Spinal Injuries with the Help of Princes, Pioneers and Poets
Spinal Cord (2001) 39, 109 ± 111 ã 2001 International Medical Society of Paraplegia All rights reserved 1362 ± 4393/01 $15.00 www.nature.com/sc A tribute to the Midlands Centre for Spinal Injuries with the help of princes, pioneers and poets `Then we set out for Whitchurch and Oswestry. As we the island of Iona in the Hebrides and found entered their territory, we were met by the Princes of refuge in a monastic settlement where he became a Powys . and others . we spent the night at Christian. Oswestry, that is the tree of Saint Oswald . we were In 634, several battles and killings later, Oswald entertained most splendidly and sumptuously in the succeeded Edwin as king of Northumbria and ruled English fashion by William Fitz Alan, a hospitable over a large part of Britain. In 641 transfer of power young nobleman . .'.1 This is how Gerald of Wales, a occurred in the usual fashion when King Oswald was priest and historian who accompanied Baldwin, defeated and slain by King Penda of Mercia at the Archbishop of Canterbury on his travels through battle of Maserfeld, which then became Oswald's Tree, Britain in 1188, described a visit to Oswestry. In Oswestry.6 Things eventually calmed down and times Spinal Injuries, Oswestry is best known for its Robert became less `troublous', as they used to say. Jones and Agnes Hunt Orthopaedic Hospital, which Not far from Oswestry lies the town of Wrexham, presently celebrates the centenary of its foundation.2±5 with its Church of St. Giles (who used to be the This hospital, unlike so many others, does not bear the patron saint of the cripples, before they became the name of a religious or royal patron, but commemorates disabled). -
Choosing Your Hospital, Contact: Choosing Your Hospital
hospital your Shropshire County Primary Care Trust Choosing PHOTOGRAPHY COPYRIGHT: ALAMY, GETTY, JOHN BIRDSALL, NHS LIBRARY, REX, SPL, ZEFA/CORBIS copy of this booklet is also Crown copyright 2005. available on: www.nhs.uk A Tel: 01743 492038 Shrewsbury SY3 8DN Bicton Heath Shelton Hospital Site Quality Directorate PALS Co-ordinator Tel: 01743 285619 Shropshire SY3 7NR Shrewsbury Belle Vue Prospect House Suite 1A Booking and Information Bureau For more help with choosing your hospital, contact: © 270744/180 What is patient choice? Things to think about If you and your GP decide that you need to see a specialist Where can I go for treatment? for further treatment, you can now choose where to have You might already have experience of a particular hospital or know someone who has. Now you can choose – where would you like to go? Or, if you like, your treatment from a list of hospitals or clinics. From April, your GP can recommend a hospital where you can be treated. you may have an even bigger choice – full details will be How do I find out more information on the NHS website (www.nhs.uk). about my condition? Your GP should be able to give you the answers to some of the questions This guide explains more about how the process works. you have. Or contact NHS Direct: visit www.nhsdirect.nhs.uk or call It also gives you answers to some questions you may have. 0845 4647 and ask to speak to a health information advisor. Plus, there are details of the hospitals you can choose and How long will it take? some information to help you choose the one that will be How quickly do you want to be treated? Would you be willing to travel best for you. -
Highland Council Archive
1 L/D73: MacColl papers RECORDS’ IDENTITY STATEMENT Reference number: GB3218/L/D73 Alternative reference number: N/A Title: MacColl papers Dates: 1811-1974 Level of description: Fonds Extent: 16 linear metres Format: Paper, photographs, wooden objects RECORDS’ CONTEXT Names of creators: Hugh Geoffrey MacColl and his ancestors and family; Clan MacColl Society Administrative history: Hugh MacColl, tailor in Glasgow (1813- 1882), whose family were originally from Mull, married in 1849 Janet Roberton (1826-1871) whose sister was Mary Christie, nee Roberton. Their children were Agnes MacColl (1852-1924), Mary Paterson MacColl (b. 1854); James Roberton MacColl (b. 1856), who emigrated to the USA, Rev. John MacColl, (b. 1863); whose sons were Dr Hugh Ernest MacColl (b. 1893) and Dr Robert Balderston MacColl (b. 1896); Rev. Alexander MacColl, (b. 1866) who also emigrated to the USA and became minister of the 2nd Presbyterian Church in Philadelphia in 1911; Jane Wilson MacColl (b. 1859) and Hugh MacColl (1861-1915). Hugh MacColl (1861-1915) was born in Glasgow on 30 June 1861 and became an apprentice engineer at Robert Napier & Sons on the Clyde in 1876. While employed here as a draftsman, he pursued further technical studies at Anderson’s College (now the University of Strathclyde). After GB3218/ 08/12/08 2 this, he became a draftsman at the Central Marine Engine Works at Hartlepool, and then at Harland & Wolff in Belfast, before returning to Glasgow as chief draftsman with James Howden & Co. In 1889, he was appointed technical manager of the engineering works of Portilla, White & Co., in Seville in Spain, where he was known as ‘Don Hugo’ and where he remained until 1895, when he returned to Britain and founded the Wreath Quay Engineering Works in Sunderland, later known as MacColl & Pollock. -
A Century of International Progress and Tradition in Surgery
Liebermann-Meffert, White A Century of International Progress and Tradition in Surgery A Century of International Progress and Tradition in Surgery An Illustrated History of the International Society of Surgery D. Liebermann-Meffert, H.White In collaboration with H.J. Stein, M. Feith and V. Bertschi Kaden Verlag Heidelberg IV liebermann-meffert · white Die Deutsche Bibliothek – CIP-Einheitsaufnahme Liebermann-Meffert, Dorothea; White, Harvey: A Century of International Progress and Tradition in Surgery; An Illustrated History of the International Society of Surgery / by Dorothea Liebermann-Meffert, Harvey White. In collab. with H.J. Stein, M. Feith, V. Bertschi. – Heidelberg : Kaden, 2001 ISBN 3-922777-42-2 © 2001 Kaden Verlag, Heidelberg, Germany Typesetting: Ch. Molter, Kaden Verlag, 69115 Heidelberg, Germany Printing and Binding: Wesel Druckerei GmbH & Co. KG, 76534 Baden-Baden, Germany ISBN 3-922777-42-2 This book is protected by copyright. Reprinting, translation, copying of illustrations, copying by means of photomechanical devices or similar, storage in data processing systems or on electronic data storage media, as well as provision of the content in the Internet or other systems of communication only with previous written permission from the publisher. Any infringement of these rights, even in the form of excerpts, is punishable by law. a century of international progress and tradition in surgery V Foreword As the International Surgical Society (ISS)/Societé Internationale de Chirurgie (SIC) celebrates its centenary at this 39th Congress in Brussels, the city where the Society was founded and where its Secretariat was located for many years, it is an opportune time for a history of the Society to be published. -
Seeing Ourselves on Stage
Seeing Ourselves on Stage: Revealing Ideas about Pākehā Cultural Identity through Theatrical Performance Adriann Anne Herron Smith Thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy University of Otago 2010 Acknowledgements Thanks to my Kaitiaki Rangimoana Taylor My Supervisors: Henry Johnson, Jerry Jaffe, Erich Kolig (2004-July 2006), Martin Tolich (July 2007 onwards) Thanks to my children Ruth Kathryne Cook and Madeline Anne Hinehauone Cook for supporting me in this work. Thanks also to Hilary Halba and Alison East for their help, encouragement and invigorating discussion; to friend and poet Roma Potiki who offered the title for this thesis and also engaged in spirited discussion about its contents; to Monika Smith, Adrienne Jansen, Geesina Zimmermann, Annie Hay Mackenzie and to all of my friends who have supported this project; Thanks to Louise Kewene, Trevor Deaker, Martyn Roberts and Morag Anne Baillie for technical support during this project. Thanks to all of the artists who have made this work possible: Christopher Blake, Gary Henderson, Lyne Pringle, Kilda Northcott, Andrew London and to Hilary Norris, Hilary Halba, Alison East and Lisa Warrington who contributed their time, experience and passion for the work of Aotearoa/New Zealand to this endeavour. ii Abstract This is the first detailed study of New Zealand theatrical performance that has investigated the concepts of a Pākehā worldview. It thus contributes to the growing body of critical analysis of the theatre Aotearoa/New Zealand, and to an overall picture of Pākehā New Zealander cultural identity. The researcher‘s experience of being Pākehā has formed the lens through which these performance works are viewed. -
The Descendants of John Pease 1
The Descendants of John Pease 1 John Pease John married someone. He had three children: Edward, Richard and John. Edward Pease, son of John Pease, was born in 1515. Basic notes: He lived at Great Stambridge, Essex. From the records of Great Stambridge. 1494/5 Essex Record office, Biography Pease. The Pease Family, Essex, York, Durham, 10 Henry VII - 35 Victoria. 1872. Joseph Forbe and Charles Pease. John Pease. Defendant in a plea touching lands in the County of Essex 10 Henry VII, 1494/5. Issue:- Edward Pease of Fishlake, Yorkshire. Richard Pease of Mash, Stanbridge Essex. John Pease married Juliana, seized of divers lands etc. Essex. Temp Henry VIII & Elizabeth. He lived at Fishlake, Yorkshire. Edward married someone. He had six children: William, Thomas, Richard, Robert, George and Arthur. William Pease was born in 1530 in Fishlake, Yorkshire and died on 10 Mar 1597 in Fishlake, Yorkshire. William married Margaret in 1561. Margaret was buried on 25 Oct 1565 in Fishlake, Yorkshire. They had two children: Sibilla and William. Sibilla Pease was born on 4 Sep 1562 in Fishlake, Yorkshire. Basic notes: She was baptised on 12 Oct 1562. Sibilla married Edward Eccles. William Pease was buried on 25 Apr 1586. Basic notes: He was baptised on 29 May 1565. William next married Alicia Clyff on 25 Nov 1565 in Fishlake, Yorkshire. Alicia was buried on 19 May 1601. They had one daughter: Maria. Maria Pease Thomas Pease Richard Pease Richard married Elizabeth Pearson. Robert Pease George Pease George married Susanna ?. They had six children: Robert, Nicholas, Elizabeth, Alicia, Francis and Thomas.