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NASA SP-7011(334)

I

AEROSPACE MEDICINE AND BIOLOGY

A CONTINUING BIBLIOGRAPHY WITH INDEXES

(Supplement 334)

A selection of annotated references to unclassifiedreports and journal articles that were introduced into the NASA scientific and technical informationsystem and announced in February 1990 in

Scientific and Technical Aerospace Reports (STAR) International Aerospace Abstracts (IAA).

National Aeronautics and Space Administration Office of Management Scientific and Technical Information Division Washington. DC 1990 This supplement is available from the National Technical Information Service (NTIS), Springfield, Virginia 22161, price code A05. INTRODUCTION

This Supplement to Aerospace Medicine and Biology lists 254 reports, articles and other docu- I ments announced during February 1990 in Scientific and Technical Aerospace Reports (STAR) or in lnternationalAerospaceAbstracts (IAA). The first issue of the bibliography was published in July 1964. 1 I In its subject coverage, Aerospace Medicine and Biologyconcentrateson the biological, physiolog- 1, ical, psychological, and environmental effects to which man is subjected during and following simulated I or actual in the Earth’s atmosphere or in interplanetary space. References describing similar effects on biological organisms of lower order are also included. Such related topics as sanitary problems, , toxicology, safety and survival, life support systems, exobiology, and person- nel factors receive appropriate attention. In general, emphasis is placed on applied research, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion. Each entry in the bibliography consists of a bibliographic citation accompanied in most cases by an abstract. The listing of the entries is arranged by STAR categories 51 through 55, the Life Sciences division. The citations, and abstracts when available, are reproduced exactly as they appeared originally in IAA or STAR, including the original accession numbers from the respective announcement journals.

I The IAA items will precede the STAR items within each category. Seven indexes - subject, personal author, corporate source, foreign technology, contract, report number, and accession number - are included. An annual index will be prepared at the end of the calendar year covering all documents listed in the 1990 Supplements.

Informationon the availability of cited publications including addresses of organizations and NTlS price schedules is located at the back of this bibliography.

iii TABLE OF CONTENTS

I Page

I Category 51 Life Sciences (General) 23

Category 52 Aerospace Medicine 37 I Includes physiological factors; biological effects of radiation; and effects of weightlessness on man and animals.

Category 53 Behavioral Sciences 51 Includes psychological factors; individual and group behavior; crew training and evaluation; and psychiatric research.

Category 54 Man/System Technology and Life Support 54 Includes human engineering; biotechnology; and space suits and protective clothing.

Category 55 Space Biology 63 Includes exobiology; planetary biology; and extraterrestrial life.

Subject Index ...... A-1 Personal Author Index ...... B-1 Corporate Source Index ...... C-1 Foreign Technology Index ...... D-1 Contract Number Index ...... E-1 Report Number Index ...... F-1 Accession Number Index ...... G-1

V TYPICAL REPORT CITATION AND ABSTRACT

NASA SPONSORED ON MICROFICHE CORPORATE SOURCE ll t ACCESSION NUMBER -N90-10571*# Virginia Univ., Charlottesville. Dept. of Environmental Sciences. TITLE-A SIMPLE, MASS BALANCE MODEL OF CARBON FLOW IN A AUTHOR AND CONTROLLED ECOLOGICAL LIFE SUPPORT SYSTEM PUBLICATION DATE -JAY L. GARLAND Mar. 1989 37 p Prepared in cooperation with Bionetics Corp., Cocoa Beach, FL CONTRACT NUMBER -(Contract NAS10-10285) AVAILABILITY SOURCE REPORT NUMBERS -(NASA-TM-102151; NAS 1.15:102151) Avail: NTIS%C AO3/MF A01 -PRICE CODE COSATI CODE -CSCL 05/8 Internal cycling of chemical elements is a fundamental aspect of a Controlled Ecological Life Support System (CELSS). Mathematical models are useful tools for evaluating fluxes and reservoirs of elements associated with potential CELSS configurations. A simple mass balance model of carbon flow in CELSS was developed based on data from the CELSS Breadboard project at Kennedy Space Center. All carbon reservoirs and fluxes were calculated based on steady state conditions and modelled using linear, donor-controlled transfer coefficients. The linear expression of photosynthetic flux was replaced with Michaelis-Menten kinetics based on dynamical analysis of the model which found that the latter produced more adequate model output. Sensitivity analysis of the model indicated that accurate determination of the maximum rate of gross primary production is critical to the development of an accurate model of carbon flow. Atmospheric carbon dioxide was particularly sensitive to changes in photosynthetic rate. The small reservoir of C02 relative to large C02 fluxes increases the potential for volatility in C02 concentration. Feedback control mechanisms regulating C02 concentration will probably be necessary in a CELSS to reduce this system instability. Author

TYPICAL JOURNAL ARTICLE CITATION AND ABSTRACT

NASASPONSORED I CORPORATE SOURCE

ACCESSION NUMBER -A90-11091* Krug International, San Antonio, TX. TITLE -DETERMINING A BENDS-PREVENTING PRESSURE FOR A SPACE SUIT AUTHORS- R. W. KRUTZ, JR., J. T. WEBB (Krug International, Technology -AUTHORS’ AFFILIATION Services Div., San Antonio, TX), and G. A. DIXON (USAF, School of Aerospace Medicine, Brooks AFB, TX) SAFE Journal, vol. 19 PUBLICATION DATE -Fall 1989, p. 20-24. Research sponsored by USAF. refs JOURNAL TITLE (Contract NASA ORDER T-82170) Copyright Research conducted to determine the proper pressure for preventing bends during EVA without preoxygenation is examined. Male and female subjects with different breathing gas mixtures and pressures are studied in order to define the pressure. Visual and auditory Doppler ultrasonicsignals are utilized to monitor intravascular gas bubbles. The workload, which simulates EVA, consists of a handturned bicycle ergometer, a torque wrench operation, and a rope pull. The experimental data reveal that the minimum space suit pressure needed to prevent decompression sickness is 9.5 psi. I.F.

vi 1 AEROSPACE MEDICINE 'I AND BIOLOGY A Continuing Bibliography (Suppl. 334) I I I MARCH 1990

51 flights and of using plant cell cultures to produce medicinal and other useful substances in space cell biotechnologies are LIFE SCIENCES (GENERAL) investigated. C.E. A90-13634# CELL MECHANISMS OF ADAPTATION TO MAIN FACTORS OF SPACE FLIGHT E. L. KORDIUM, E. M. NEDUKHA, IU. A. POLULIAKH, A. F. A90-13607# POPOVA, K. M. SYTNIK (AN USSR, lnstitut Botaniki, Kiev, EFFECT OF SPACE FLIGHTS AND HYPOKINESIA ON Ukrainian SSR) et al. IAF, International Astronautical Congress, PLASMA INSULIN LEVELS AND INSULIN RECEPTORS IN RAT 40th, Malaga, Spain, Oct. 7-13, 1989. 8 p. refs LIVER (IAF PAPER 89-606) Copyright L. MACHO, E. SVABOVA, M. FICKOVA, S. ZORAD (Slovenska Cytological and biochemical research was conducted on Akademia Vied, Ustav Experimentalnej Endokrinologie, Bratislava, unicellular and multicellular plants growing under conditions of Czechoslovakia), L. SEROVA (Institut Mediko-Biologicheskikh short-term and long-term orbital flights, and flight factors such as Problem, Moscow, USSR) et al. IAF, International Astronautical microgravity were simulated. These investigations were used to Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 5 p. refs evaluate previously proposed mechanisms for the adaptation of (IAF PAPER 89-564) Copyright plant forms to these space conditions on the cellular, subcellular, Hypokinesia is introduced as a model for simulation of the and membrane levels. An increased activity of hydrolytic enzymes effects of animal stay in microgravity and other space flight was found which indicates the accelerated development and aging conditions. The plasma insulin levels and insulin binding to liver of organisms under the effect of orbital flight factors. B.J. cell membrane and to isolated adipocytes in rats exposed to hypokinesia were investigated. The simulation of the effects of A90-13635# microgravity by immobilization of animals in special cages for 1 BEHAVIOUR OF SINGLE-CELL ORGANISMS EXPOSED TO and 7 days showed only a slight decrease in plasma insulin levels HY PERGRAVITY in 7-day hypokinetic animals as compared to control rats. It was H. PLANEL, G. RICHOILLEY, C. CARATERO, R. TIXADOR, A. found that binding of insulin to receptors of liver cell membranes CARATERO (Toulouse 111, Universite, France) et al. IAF, in rats exposed to hypokinesia for 1 or 7 days is not significantly International Astronautical Congress, 40th, Malaga, Spain, Oct. different from controls, however in isolated adipocytes, an important 7-13, 1989. 11 p. refs decrease of total binding capacity and number of insulin receptors (IAF PAPER 89-607) was found in rats exposed to hypokinesia for 1 day period. For 7- The paper shows the results of investigations carried out in and 21-day hypokinetic animals, the values of binding capacity for two single cell organisms, Paramecium t. and Tetrahymena p., insulin and number of receptors in adipocytes were not very exposed to different gravitational levels. In paramecium, different from those in controls. The determination of insulin binding hypergravity resulted in a decrease in cell growth rate. The results in adipocytes from adrenalectomized or dexamethasone treated depend on g level and angular speed of the centrifuge; furthermore rats exposed to hypokinesia indicated that glucocorticoids have a the responses depend also on small short fluctuations in g levels, regulatory role in decrease of insulin receptors during short-term due to the swimming of the cells inside the culture tubes. In hypokinesia. C.E. contrast, the proliferation of Tetrahymena is stimulated by hypergravity. It can be pointed out that paramecium and A90-13617# Tegrahymena are both free swimming cells, belonging to the same PROSPECTS OF STUDIES IN SPACE PHYTOBIOLOGY group of Ciliates. Author E. L. KORDIUM, P. G. SIDORENKO, D. A. KLIMCHUK, G. M. MARTIN, S. I. ZHADKO (AN USSR, lnstitut Botaniki, Kiev, Ukrainian A90-13636# SSR) et al. IAF, International Astronautical Congress, 40th, POLARITY OF ROOT STATOCYTES IN SPACE AND IN Malaga, Spain, Oct. 7-13, 1989. 8 p. refs SIMULATED MICROGRAVITY (IAF PAPER 89-578) Copyright G. LORENZI, G. PERBAL (Paris VI, Universite, France), M. Fundamental and important application problems in space ALEXANDRE, A. ISAMBERT, and D. DEPEYRE (Paris, Ecole phytobiology research are analyzed. The problems considered Centrale, France) IAF, International Astronautical Congress, 40th, include the following: mechanisms of gravi-, photo-, and Malaga, Spain, Oct. 7-13, 1989. 6 p. refs chemotropisms under gravitational and orbital flight conditions; (IAF PAPER 89-608) Copyright structuraVfunctionaI organization and reproductionldifferentiation Roots of lens culinaris L. cv. Verte du Puy were germinated of various types of cells of vegetative and generative organs in and grown at 1 g on the ground, on a 1-g centrifuge in space, in plant ontogenesis as affected by microgravity; the role of calcium simulated microgravity on a slow rotating clinostat (0.9 rpm) and in gravireception, dynamics of intracellular ionized calcium at microgravity in space. At 1 g, amyloplasts were sedimented on content, and localization under microgravity; physical/chemical endoplasmic reticulum, whereas in microgravity and on the clinostat organization of cell membranes and their transport characteristics they were located preferentially in the center and in the proximal under microgravity; and mechanisms of adaptation to microgravity part of the statocyte. While in cells differentiated at 1 g on ground, on cellular, subcellular, and membrane levels. An adequate system the nuclear membrane was almost in contact with the plasmalemma for analyzing space biological problems is still needed. The lining the proximal cell wall, in statocytes of roots grown on the possibilities of growing several generations of higher plants in orbital clinostat there was a distance on 0.47 micron (horizontal

23 51 LIFE SCIENCES (GENERAL)

clinorotation) and of 0.76 micron (vertical clinorotation) between K. KREUZBERG, P. BERGWEILER, U. FRIEDRICH, and HA. these membranes. However, in microgravity. the nucleus was most HOFFMANN (DLR, Cologne, Federal Republic of Germany) IAF, displaced, 0.87 micron from the proximal cell wall. Experiments International Astronautical Congress, 40th, Malaga, Spain, Oct. with Cytochalasin B indicated that the displacement of this organelle 7-13, 1989. 7 p. at low-gravity could be induced by a relaxation of the (IAF PAPER 89-612) cytoskeleton. Author The scientific objectives of the German microgravity program include research on unicellular organisms with respect to the effecty A90-13637# of gravity on cell polarity, growth, and differentiation, as well as IMPORTANCE OF THE 1G CONTROLS IN INTERPRETING THE the geotaxis mechanism; the gravisensing and graviperception RESULTS OF AN EXPERIMENT ON PLANT GRAVITROPISM mechanism of plants; and the adaptation of animals to microgravity (BIORACK, D1 MISSION) and changes in the development and differentiation of nerve and D. DRISS-ECOLE and G. PERBAL (Paris VI, Universite, France) bone cells under microgravity. A broad spectrum of flight IAF, InternationalAstronautical Congress, 40th, Malaga, Spain, Oct. opportunities for short-term missions and long-term missions (e.g., 7-13, 1989. 9 p. refs Eureca and Spacelab) and the development of corresponding flight (IAF PAPER 89-609) Copyright hardware and experimental facilities will become available to The effects of microgravity on mitotic activity, cell differentiation, German investigators over the next few years. Major progress and statocyte polarity in lentil seedlings roots was investigated concerning the mechanism of graviperception in gravitropism (Biorack, Spacelab D1 Mission, Oct-Nov 1985). Comparison of resulted from experiments in the Texus sounding rocket program. the microgravity sample and flight control demonstrated that B.J. microgravity increased mitotic activity and cell elongation, and affected the polarity of statocytes. The samples grown first in A90- 13903 microgravity and then subjected to a 3-h centrifugation confirm ADVANCES IN COMBUSTION TOXICOLOGY. VOLUMES 1 & 2 the action of near 0 g on mitotic activity and cell elongation and GORDON E. HARTZELL, ED. (Southwest Research Institute, San show that the location of the nucleus within the statocytes is Antonio, TX) Lancaster, PA, Technomic Publishing Co., Inc., dependent upon gravity. The specimens must be fixed in space, 1989, p. Vol. 1, 334 p.; vol. 2, 327 p. No individual items are since even a short period of exposure to gravity has an effect on abstracted in this volume. the mitotic activity of the root and on the polarity of the Copyright statocytes. Author Problems in combustion toxicity (CT) are examined in a collection of reviews and technical papers published during the A90-13638# period 1983-1987. Topics addressed include biological studies of RESPONSE OF UNICELLULAR ORGANISMS TO THE combustion atmospheres, the effect of heating rate on the CT of CONDITIONS IN LOW EARTH ORBIT evolved products, the CT of polyvinyl chloride, the CT of nonmetallic HORST-DIETER MENNIGMANN (Frankfurt, Universitaet, Frankfurt electrical tubing, a bioassay test for the incapacitating effects of am Main, Federal Republic of Germany) IAF, International exposure to combustion atmospheres, the acute inhalation CT of Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 11 smoke from five halogenated polymers, the CT of acrolein and p. refs CO, a radiant-furnace fire model for evaluating acute smoke CT, (IAF PAPER 89-610) Copyright and the evaluation of smoke CT using concentration-timeproducts. Results of experiments on unicellular microorganisms conducted Consideration is given to numerical modeling of fire-gas CT, in spacecraft in low earth orbit are presented to show that the pulmonary-tissue reactions to smoke injury, CT of thermal- behavior of unicellular organisms in the microgravity environment decomposition products from composites, a CT evaluation differs from their behavior on earth. Depending on the organism of fire gases from experimental fires in a building, and risk-oriented studied, differences have been observed, among others, in the evaluation of fire-gas CT based on laboratory-scale experiments cell wall structure, functions, growth rate, yield of biomass, and using the DIN 53436 method. T.K. production and consumption of specific substances. While some experiments suggest that the cells are affected by special radiation A90-14446 conditions, most of the experiments indicate that the differences DEPENDENCE OF THE AMPLITUDE OF KINESTHETIC are due to the reduction in gravity. V.L. EVOKED POTENTIALS ON THE VELOCITY AND ACCELERATION OF THE MOTION OF A MONKEY'S HAND A90-13639# [ZAVISIMOST' AMPLITUDY KINESTETICHESKIKH STUDY OF ACTIVATION OF HUMAN PERIPHERAL BLOOD VYZVANNYKH POTENTSIALOV OT SKOROSTI I USKORENllA MONONUCLEAR CELLS AFrER A SPACE FLIGHT DVlZHENllA RUKl U OBEZ'IAN] L. SCHAFFAR, B. FERRUA, S. MANIE, M. LIMOUSE (Nice, E. IU. GOLOV and V. A. FEDAN (Nauchno-lssledovatel'skaia Universite, France), 1. KONSTANTINOVA (Instiut Laboratoriia Biologicheski Aktivnykh Veshchestv Gidrobiontov, Mediko-Biologicheskikh Problem, Moscow, USSR) et al. IAF, Moscow, USSR) Akademiia Nauk SSSR, Doklady (ISSN International Astronautical Congress, 40th. Malaga, Spain, Oct. 0002-3264), vol. 308, no. 2, 1989, p. 494-496. In Russian. refs 7-13, 1989. 6 p. Research supported by CNES. refs Copyright (IAF PAPER 89-61 1) Copyright The effects of a space flight on the major biological processes A90-1463 1 of T lymphocyte proliferation were analyzed in three cosmonauts EVIDENCE FOR ANOXYGENIC PHOTOSYNTHESIS FROM THE after a long duration mission (26 to 151 days). Interleukin-1 DISTRIBUTION OF BACTERIOCHLOROPHYLLS IN THE secretion by peripheral blood monocytes from cosmonauts did BLACK SEA not significantly differ after landing from preflight values. Also, D. J. REPETA, D. J. SIMPSON, H. W. JANNASCH (Woods Hole interleukin-2 receptor was normally expressed on T lymphocytes Oceanographic Institution, MA), and 6. B. JORGENSEN (Aarhus after the flight. However, a significant increase of interleukin 2 Universitet, Denmark) Nature (ISSN 0028-0836), vol. 342, Nov. production was clearly observed in two cosmonauts after landing. 2, 1989, p. 69-72. Research supported by NSF. refs These results indicate that the ability of human lymphocytes and Copyright monocytes to be in vitro activated is not affected after a long Results are reported from analyses of photosynthetic pigments duration space mission. Author in samples of suspended particulate matter collected from two stations in the western basin of the Black Sea. The data A90-13640# demonstrate high concentrations of a bacteriochlorophyll at the GRAVITATIONAL BIOLOGY WITHIN THE GERMAN chemocline, and thus the potential for anoxygenic photosynthesis MICROGRAVITY PROGRAM - CURRENT STATUS AND as a component of primary production in the carbon cycle of the FURTHER PURSUITS Black Sea. More than 95 percent of the pigments in the

24 51 LIFE SCIENCES (GENERAL)

bacteriochlorophyll maximum are accounted for by a series of and responsible for a decrease in bone strength. Adaptive changes , aromatic carotenoids and bacteriochlorophylls-e, including a in muscle functions of specific skeletal compartments may play a previously unreported geranyl ester of 4-i-butyl bacterio- role in different bone responses to weightlessness. C.E. chlorophyll-e. The distribution of pigments is characteristic of the obligate phototrophs Chlorobium phaeobacteroides and C. A90-15053 I phaeovibriodes. Total depth-integated bacteriochlorophyll at one EVALUATION OF EXPERIMENTS INVOLVING THE STUDY OF station exceeded total chlorophyll-a in the overlying oxygenated PLANT ORIENTATION AND GROWTH UNDER DIFFERENT portion of the euphotic zone. C.D. GRAVITATIONAL CONDITIONS A. J. MERKYS, R. S. LAURINAVICIUS, D. V. SVEGZDIENE, D. P. A90-15051 RAKLEVICIENE, A. V. JAROSIUS (AN LSSR, lnstitut Botaniki, 1 LIFE SCIENCES AND SPACE RESEARCH XXlll(5) - Vilnius, Lithuanian SSR) et al. (COSPAR, IAU, International Union GRAVITATIONAL BIOLOGY; PROCEEDINGS OF THE TOPICAL of Physiological Sciences, and International Academy of MEETING AND WORKSHOPS XVll AND XVlll OF THE 2TTH Astronautics, Plenary Meeting and Workshops XVll and XVlll on COSPAR PLENARY MEETING, ESPOO, FINLAND, JULY 18-29, Life Sciences and Space Research XXlll(5) - Gravitational Biology, ' 1988 Espoo, Finland, July 18-29, 1988) Advances in Space Research H. OSER, ED. (ESA, Microgravity Office, Paris, France), G. (ISSN 0273-1177), vol. 9, no. 11, 1989, p. 23-32. refs HORNECK, ED. (DLR, lnstitut fuer Flugmedizin, Cologne, Federal Copyright Republic of Germany), A. GOGOLI, ED. (Zuerich, Eidgenoessische The effect of gravity on the phylogenesis of plants is examined. Technische Hochschule, Zurich, Switzerland), G. A. UBBELS, ED. The effects of microgravity on the spatial orientation, (Netherlands Institute for Developmental Biology, Utrecht), J. morphogenesis, cellular growth, and generative development of WETZIG, ED. (Mainz, Universitaet, Federal Republic of Germany) plants are discussed. Results are presented from spaceflight et al. Meeting and Workshops sponsored by COSPAR, IAU, experiments on plant ontogenesis, showing structurally modified, International Union of Physiological Sciences, and International but normally functioning development. Data are on integral and Academy of Astronautics. Advances in Space Research (ISSN cellular growth of the axial organs of seedlings, and the 0273-1177), vol. 9, no. 11, 1989, 301 p. For individual items see morphological structure and developmental rates of plants during A90-15052 to A90-15085. prolonged growth in space. The relationship between the direction Copyright of the predominant gravitational vector and plant growth and Papers on gravitational biology are presented, including results phylogenesis is considered. R.B. from spaceflight and simulation experiments and studies of the relationships between gravity and developmental biology, A90-15054 embryology, neurovestibular research, and biorhythms. Specific PLANT CELL IN THE PROCESS OF THE ADAPTATION TO topics include microgravity and mammalian musculoskeletal SIMULATED MICROGRAVITY systems, plant orientation and growth under various gravitational E. L. KORDIUM (AN USSR, lnstitut Botaniki, Kiev, Ukrainian SSR) conditions, the calcium gradient in plant cells with polarized growth (COSPAR, IAU, International Union of Physiological Sciences, and in microgravity, the effects of HZE particles on plant seeds, and a International Academy of Astronautics, Plenary Meeting and Space Shuttle experiment on aggregation of red cells and Workshops XVll and Wlll on Life Sciences and Space Research thrombocytes in heart disease and hyperlipidaemia. Additional XXlll(5) - Gravitational Biology, Espoo, Finland, July 18-29, 1988) topics include free flow electrophoresis in the Space Shuttle Advances in Space Research (ISSN 0273-1177), vol. 9, no. 11, program, mammalian cell cultivation in space, the geotropic 1989, p. 33-36. refs sensitivity of hornets, the amphibian egg as a model system for Copyright studying gravitational effects, early development in the mouse under Results are presented from the study of structural and functional microgravity, the effect of gravitoinertial force on vestibular rearrangements in the organelles of meristematic, differentiating, nystagmus in man observed in a centrifuge, dorsal light response and differentiated cells of 7- and 14-day old pea roots under under varying acceleration, the biological clock of Neurospora in microgravity. It is found that the organelles in a cell population microgravity, and gravitational biology and the circadian timing are heterogeneous with respect to the degree of the system. R.B. rearrangements. Under changes in functional load, increased reactivity during cell growth and rearrangements is observed. The A90-15052 results suggest that microgravity does not prevent the development MICROGRAVITY AND MUSCULOSKELETAL SYSTEM OF of certain adaptative reactions at the cellular level. R.B. MAMMALS E. A. IL'IN and V. S. OGANOV (Institut Mediko-Biologicheskikh A90-15055 Problem, Moscow, USSR) (COSPAR, IAU, International Union of FORMATION AND GROWTH OF CALLUS TISSUE OF Physiological Sciences, and International Academy of Astronautics, ARABIDOPSIS UNDER CHANGED GRAVITY Plenary Meeting and Workshops XVll and XVlll on Life Sciences A. J. MERKYS, R. S. LAURINAVICIUS, P. F. KENSTAVICIENE, and Space Research XXlll(5) - Gravitational Biology, Espoo, and G. S. NECITAILO (AN LSSR, lnstitut Botaniki, Vilnius, Finland, July 18-29, 1988) Advances in Space Research (ISSN Lithuanian SSR) (COSPAR, IAU, International Union of 0273-1177), vol. 9, no. 11, 1989, p. 11-19. refs Physiological Sciences, and International Academy of Astronautics, Copyright Plenary Meeting and Workshops XVll and XVlll on Life Sciences Data and findings concerning the effects of weightlessness on and Space Research XXlll(5) - Gravitational Biology, Espoo, bones and muscles of white rats flown on Cosmos biosatellites Finland, July 18-29, 1988) Advances in Space Research (ISSN and Spacelab-3 are reviewed. It is found that the magnitude and 0273-1 177), vol. 9, no. 11, 1989, p. 37-40. sign of functional changes in muscles depend on their Copyright biomechanical profile. In five to seven day flights, muscle Results are presented from the study of morphological contractility changes are mainly associated with a diminished alterations in a cell population during the fomation of Arabidopsis activity of excitation-contractioncoupling, while in long-term flights callus tissue on a clinostat and on the orbital station Salyut-7. those changes are produced by changes in myosin populations The gravity environment in space does not prevent the process specific for myofibers of different functional profile. Osteoporosis of cell dedifferentiation and formation of callus tissue. The callus and bone demineralization are very mild at early flight stages up grown in space is more dense and has less meristematic centers to 1 week. As a result, decrease in bone mechanical strength than the callus grown on a vertical clinostat. Also, the clinostat may be caused by changes in physicochemical parameters of the cells display a higher proliferative activity and have a larger average collagen crystal system. Noticeable osteoporosis develops in flights size and nuclei area, compared with the cells grown in space. of up to 3 weeks, primarily produced by osteogenesis inhibition R.B.

25 51 LIFE SCIENCES (GENERAL)

A90-15056 A90-15059 CALCIUM GRADIENT IN PLANT CELLS WITH POLARIZED GRAVITY AND THE MEMBRANE-SOLUTION INTERFACE - GROWTH IN SIMULATED MICROGRAVITY THEORETICAL INVESTIGATIONS K. M. SYTNIK, 0. T. DEMKIV, E. L. KORDIUM, E. M. NEDUKHA, A. SCHATZ and A. LINKE-HOMMES (DLR, lnstitut fuer Flugmedizin, and L. A. DANEVICH (AN USSR, lnstitut Botaniki, Kiev, Ukrainian Cologne, Federal Republic of Germany) (COSPAR, IAU, SSR) (COSPAR, IAU, International Union of Physiological International Union of Physiological Sciences, and International Sciences, and International Academy of Astronautics, Plenary Academy of Astronautics, Plenary Meeting and Workshops XVll Meeting and Workshops XVll and XVlll on Life Sciences and Space and XVlll on Life Sciences and Space Research XXlll(5) - Research XXlll(5) - Gravitational Biology, Espoo, Finland, July Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. 9, no. 11, 1989, p. 41-44. refs 61-64. refs Copyright Copyright The gravity response mechanisms of plant cells characterized The theory of concentrationand potential variations at interfaces by apical growth is studied, including the initiation of cell polarity. is applied to different membrane-solution systems to calculate Chlorotetracycline, a fluorescent calcium probe, was used to density variations. The theory is modified to take care of the finite determine the calcium distribution gradient in root hair and apical volumes in electrolytes. The model is a phospholipid membrane cells. It is found that irradiation by red light leads to a sharp with a surface charge density of -4.824 x 10 to the -6th (As/sq decrease in the Ca(2+) gradient in cells. It is shown that darkness cm) in contact with KCI, NaCI, and CaC12 solutions and mixtures. does not considerably alter the of calcium influx and Maximal density variations of about 0.04 (g/cu cm) were found in distribution during clinostatting. The results confirm that the Ca(2+) surface layers between the membrane and the solutions. The ion has a functional role in apical growth and suggest that gravity extension of the layers is in the range of 1 to 6 nm. The results plays a part in the redistribution or activation of ion channels in are of interest in connection with the effects of gravity on biological the plasmalemma. R.B. organisms in space flight. C.E.

A90-15061 PLANT CELL PLASMA MEMBRANE STRUCTURE AND A90-15057 PROPERTIES UNDER CLINOSTATTING BIOLOGICAL EFFECTS OF GALACTIC RADIATION HZE IU. A. POLULAKH, S. I. ZHADKO, D. A. KLIMCHUK, V. A. PARTICLES IN EXPERIMENTS ON THE ORBITAL STATION BARABOI, A. N. ALPATOV (AN USSR, lnstitut Botaniki; Research I SALYUT 7 Institute of Roentgeno-Radiology and Oncology, Kiev, Ukrainian A. T. MILLER and L. V. NEVZGODINA (Institut SSR) et al. (COSPAR, IAU, International Union of Physiological Mediko-Biologicheskikh Problem, Moscow, USSR) (COSPAR, IAU, Sciences, and International Academy of Astronautics, Plenary International Union of Physiological Sciences, and International Meeting and Workshops XVll and XVlll on Life Sciences and Space Academy of Astronautics, Plenary Meeting and Workshops XVll Research XXlIl(5) - Gravitational Biology, Espoo, Finland, July and XVlll on Life Sciences and Space Research XXlll(5) - 18-29, 1988) Advances in Space Research (ISSN 0273-1177), vol. Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances 9, no. 11, 1989, p. 71 -74. refs in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. Copyright 47-51. refs Chemiluminescene, fluorescence probes, , and Copyright freeze-fracture studies are used to examine the structural and Consideration is given to the extent of radiation damage to functional organization of the plasma membrane of seedling pea lettuce (Lactuca sativa) seeds flown on the orbital station Salyut roots under normal conditions and clinostalting. Changes in 7 for 66 to 457 days. It is found that a single HZE particle hitting plasmalemma microviscosity and phosphatidilcholine and a seed has little effect on subsequent plant growth. Various phosphatidilethanolamine content are discussed. Tables of morphological anomalies in primordial leaves and roots show a variations in phospholipid and fatty acid contents are given. The correlation with the location of the HZE particle track. Light and results suggest that changes in lipid peroxidation lead to plasma electron microscopy show the presence of channels in dry and membrane destruction. These changes display phase charac- soaked seeds. It is suggested that these channels are related to teristics, however, and promote a renewal of membrane the LET of the incident particle. The implications of the study for lipid content. R.B. space flight radiation hazards are noted. R.B. A90-15062 POTENTIAL SITES FOR THE PERCEPTION OF GRAVITY IN A90-15058 THE ACELLULAR SLIME MOLD PHYSARUM POLYCEPHALUM EFFECTS OF PROLONGED EXPOSURE OF LETTUCE SEEDS 1. BLOCK and W. BRIEGLEB (DLR, lnstitut fuer Flugmedizin, TO HZE PARTICLES ON ORBITAL STATIONS Cologne, Federal Republic of Germany) (COSPAR, IAU, L. V. NEVZGODINA, E. N. MAKSIMOVA, and E. V. KAMINSKAIA International Union of Physiological Sciences, and International (Institut Mediko-Biologicheskikh Problem, Moscow, USSR) Academy of Astronautics, Plenary Meeting and Workshops XVll (COSPAR, IAU, International Union of Physiological Sciences, and and XVlll on Life Sciences and Space Research XXlll(5) - International Academy of Astronautics, Plenary Meeting and Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances Workshops XVll and XVlll on Life Sciences and Space Research in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. XXlll(5) - Gravitational Biology, Espoo, Finland, July 18-29, 1988) 75-78. refs Advances in Space Research (ISSN 0273-1177). vol. 9, no. 11, Copyright 1989, p. 53-58. refs Gravisensitivity of the acellular slime mold Physarum Copyright polycephalum has been established in simulated and real The effects of HZE particles on lettuce (Lactuca sative) seeds near-weightlessness experiments. Like most of the unicellular flown on the orbital stations Salyut 6 and 7 for periods between organisms, it does not possess a specialized gravireceptor. 40 and 457 days are examined. The frequency of aberrant cells Nevertheless, the slime mold Physarum polycephalum turned out is used to estimate the dependences of biological damage on to be gravisensitive, showing at least four responses to a changing flight duration, physical parameters, and the passage of an HZE gravistimulus. The microplasmodia used in the experiments showed particle through the cell. The location of tracks of individual HZE that mitochondria are prime candidates for the gravity perception, particles with atomic numbers of six or more and LET of 200 compared to nuclei, morphologic polarity, and the contractile keV/micron is determined. A much higher number of aberrant elements themselves. During the impediment of respirition, the cells and cells containing multiple chromosome aberrations was zero-g reaction is inhibited and the regulation is reduced. The observed in seeds that were hit by HZE particles. R.B. regulated response phenomena to a light stimulus strongly

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resemble the behavior under zero-g exposure. In the blue-light differentiation. Since microgravity could affect prokaryotic and reaction, a flavin of the mitochondrial matrix seems to be involved eukaryotic cells at a subcellular and molecular level, space offers in the light perception. The contraction rhythm and modulations an opportunity to learn more about basic biological systems with are coupled to rhythmic changes in the energy and Ca(2+) levels one inmportant variable removed. The thin film bioreactor will in mitochondria. C.E. facilitate the handling of fluids in microgravity, under constant temperature and will allow multiple samples of cells to be grown A90-15063 with variable conditions. Studies on cell cultures grown in ULTRASTRUCTURAL AND GROWTH INDICES OF microgravity would make it possible to identify and quantify changes CHLORELLA CULTURE IN MULTICOMPONENT AQUATIC in basic biological function in microgravity which are needed to SYSTEMS UNDER SPACE FLIGHT CONDITIONS develop new applications of orbital research and future A. F. POPOVA, K. M. SYTNIK, E. L. KORDIUM (AN USSR, lnstitut biotechnology. Author Botaniki, Kiev, Ukrainian SSR), G. 1. MELESHKO, V. N. SYCHEV (Institut Mediko-Biologicheskikh Problem, Moscow, USSR) et al. Awl5070 (COSPAR, IAU, International Union of Physiological Sciences, and DEVELOPMENTAL BIOLOGY IN SPACE - WHY AND HOW? International Academy of Astronautics, Plenary Meeting and G. A. UBBELS (Netherlands Institute for Developmental Biology, Workshops XVll and XVlll on Life Sciences and Space Research Utrecht) (COSPAR, IAU, International Union of Physiological XXlll(5) - Gravitational Biology, Espoo, Finland, July 18-29, 1988) Sciences, and International Academy of Astronautics, Plenary Advances in Space Research (ISSN 0273-1177), vol. 9, no. 11, Meeting and Workshops XVll and XVlll on Life Sciences and Space 1989, p. 79-82. refs Research XXlll(5) - Gravitational Biology, Espoo, Finland, July Copyright 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. Chlorella cells cultivated in a threecomponent aquatic system 9, no. 11, 1989, p. 131-134. refs in space and under normal conditions are compared, focusing on Copyright the cells' submicroscopic organization. Compared to the control The need to study the effect of weightlessness on embryonic cells, the cells cultivated in space have a lower amount of reserve development is examined. The facilities provided by Space Lab polysaccharides in their chloroplasts. The space cells also display for developmental biological experiments are described. Future increases in cell vacuolization and mitochondrionvolume, disturbed embryological research in microgravity, such as the study of cytokinesis, and altered configurations of plasmalemma different animal species, is discussed. I.F. evaginations and invaginations. Also, the space-cultivated cells were found to be more susceptible to infection by bacteria. R.B. A90-15071 INSECTS AS TEST SYSTEMS FOR ASSESSING THE A90-15064 POTENTIAL ROLE OF MICROGRAVITY IN BIOLOGICAL LONG CLINOSTATION INFLUENCE ON THE LOCALIZATION DEVELOPMENT AND EVOLUTION OF FREE AND WEAKLY BOUND CALCIUM IN CELL WALLS I. VERNOS, M. CARRATALA, J. GONZALEZ-JURADO, J. R. OF FUNARIA HYGROMETRICA MOSS PROTONEMA CELLS VALVERDE, M. CALLEJA (Madrid, Universidad Autonoma; CSIC, E. M. NEDUKHA (AN USSR, lnstitut Botaniki, Kiev, Ukrainian lnstituto de lnvestigaciones Biomedicas, Spain) et al. (COSPAR, SSR) (COSPAR, IAU, International Union of Physiological IAU, InternationalUnion of Physiological Sciences, and International Sciences, and International Academy of Astronautics, Plenary Academy of Astronautics, Plenary Meeting and Workshops XVll Meeting and Workshops XVll and XVlll on Life Sciences and Space and XVlll on Life Sciences and Space Research XXlll(5) - Research XXlll(5) - Gravitational Biology, Espoo, Finland, July Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. 9, no. 11, 1989, p. 83-86. refs 137-146. Research supported by the Comision Nacional de Copyright lnvestigacion del Espacio. refs Results are presented from a study to determine the localization Copyright of free and weakly-bound calcium and pectinases in Funaria It is argued that insects, and more specifically Drosophila hygrometrica moss protonema cells cultivated by long-duration melanogaster, are very appropriate systems for testing the clinostatting. An electroncytochemical study of control cells involvement of the physical parameters altered in space on cultivated at 1 g is also conducted. It is found that cytochemical biological devlopment and evolution. The main potential effects of reaction product deposit was more intense in the cells cultivated gravity on living systems at the organisrnal and cellular level are on the clinostat. The results suggest that the increase of free examined, taking experimental data into account. It is shown that calcium concentrations under conditions of clinostation is related cell size is of critical importance for understanding such effects. to the hydrolysis of pectinic substances and the breaking of C.D. methoxy groups of pectins. Consideration is given to possible mechanisms for the disturbance of the calcium balance of plant A90-15072 cells and the role of cell walls in the homeostasis of cells grown GEOTROPIC SENSITIVITY OF HORNETS under simulated microgravity. R.B. JACOB S. ISHAY, EYAL ROSENZWEIG, OFER ROSENZWEIG, and SAMUEL BERKE (Tel Aviv University, Israel) (COSPAR, A90-15068' National Aeronautics and Space Administration. IAU, International Union of Physiological Sciences, and International Lyndon 6. Johnson Space Center, Houston, TX. Academy of Astronautics, Plenary Meeting and Workshops XVll THIN FILM BIOREACTORS IN SPACE and XVlll on Life Sciences and Space Research XXlll(5) - M. HUGHES-FULFORD (NASA, Johnson Space Center, Houston, Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances TX USVA, Medical Center; California, University, San Francisco, in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. CAI and H. W. SCHELD (Phyto Resource Research, Inc., College 147-155. refs Statiin, TX) (COSPAR, IAU, International Union of Physiological Copyright Sciences, and International Academy of Astronautics, Plenary Oriental Hornet workers, Vespa orientalis (Hymenoptera: Meeting and Workshops XVll and XVlll on Life Sciences and Space Vespinae) were measured for their responses to changes in the Research XXlll(5) - Gravitational Biology, Espoo, Finland, July direction of the gravitational field and this under both static and 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. kinetic (centrifugal) conditions. The hornets can build a comb 9, no. 11, 1989, p. 111-117. refs (oriented toward the gravitational force) when their multifaceted copyright eyes are covered. Building activity is undertaken in the dark as Studies from the Skylab, SL-3 and D-1 missions have well as by hornets that had been blinded or had eclosed in the demonstrated that biological organisms grown in microgravity have dark and had never seen any light. If the frons plate of hornets is changes in basic cellular functions such as DNA, mRNA and protein damaged, there is no or little building, and the comb direction is synthesis, cytoskeleton synthesis, glucose utilization, and cellular distorted. Hornets eclosing from and developing in combs subjected

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to centrifugal spinning build combs whose direction is affected (ISSN 0273-1177), vol. 9, no. 11, 1989, p. 187-197. Research both by rotation and by the resultant of the gravitational and supported by ESA and SRON. refs centrifugal forces. Author Copyright The fertilization of Xenopus frog eggs in an automatic A90-15073 experiment container on Texus-17 is studied. The container is a A STEP IN EMBRYONIC AXIS SPECIFICATION IN XENOPUS 79.5 x 19.0 x 33.1 mm block with electronics on top. The contents LAEVIS IS SIMULATED BY CYTOPLASMIC DISPLACEMENTS of the six compartments for the fertilization experiment and the ELICITED BY GRAVITY AND CENTRIFUGAL FORCE preparation of the eggs are described. The experimental data reveal STEVEN D. BLACK (Duke University, Durham, NC) (COSPAR, that fertilization of the frog eggs under microgravity is possible IAU, International Union of Physiological Sciences, and International and the automatic container is applicable for future fertilization Academy of Astronautics, Plenary Meeting and Workshops XVll experiments. I.F. and XVlll on Life Sciences and Space Research XXlll(5) - Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances A90-15077 in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. EARLY DEVELOPMENT IN THE MOUSE - WOULD IT BE 159-168. refs AFFECTED BY MICROGRAVITY? Copyright E. LEHTONEN (Helsinki, University, Finland) and M. H. L. SNOW (University College, London, England) (COSPAR, IAU, International A90-15074' Indiana Univ., Bloomington. Union of Physiological Sciences, and International Academy of THE AMPHIBIAN EGG AS A MODEL SYSTEM FOR Astronautics, Plenary Meeting and Workshops XVll and XVlll on ANALYZING GRAVITY EFFECTS Life Sciences and Space Research XXlll(5) - Gravitational Biology, G. M. MALACINSKI and A. W. NEFF (Indiana University, Espoo, Finland, July 18-29, 1988) Advances in Space Research Bloomington) (COSPAR, IAU, International Union of Physiological (ISSN 0273-1177), vol. 9, no. 11, 1989, p. 201-208. Research Sciences, and International Academy of Astronautics, Plenary supported by the Academy of Finland, Medical Research Council Meeting and Workshops XVll and XVlll on Life Sciences and Space of England, and Sigrid Juselius Foundation. refs Research XXlll(5) - Gravitational Biology, Espoo, Finland, July Copyright 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. The effects of microgravity on mouse embryogenesis are 9, no. 11, 1989, p. 169-176. refs studied. The stages of mouse embryogenesis are discussed. (Contract NAG2-323) Particular attention is given to compaction and polarization during Copyright cleavage, the establishment of the radial axis, the Amphibian eggs provide several advantageous features as a embryonic-abembryonic axis, the dorso-ventral axis, and the model system for analyzing the effects of gravity on single cells. anterior-posterioraxis, implantation, and the rotation of the embryo. Those features include large size, readily tracked intracellular It is noted that from early in development the mouse embryo inclusions, and ease of experimental manipulation. Employing novel cells are well oriented in time and space and that gravity may gravity orientation as a tool, a substantial data base is being have a role in early development; however, early embryo developed. That information is being used to construct a development is dependent on cell interaction and in normal gravity three-dimensional model of the frog (Xenopus laevis) egg. Internal the embryo regulates its own development and may be independent cytoplasmic organization (rather than surface features) are being of gravity. I.F. emphasized. Several cytoplasmic compartments (domains) have been elucidated, and their behavior in inverted eggs monitored. A90-15080 They have been incorporated into the model, and serve as a DORSAL LIGHT RESPONSE AND CHANGES OF ITS point of departure for further inquiry and speculation. Author RESPONSES UNDER VARYING ACCELERATION CONDITIONS S. WATANABE, A. TAKABAYASHI, S. TAKAGI (Nagoya University, A90-15075' Indiana Univ., Bloomington. Japan), R. VON BAUMGARTEN, and J. WETZIG (Mainz, SUBCELLULAR COMPONENTS OF THE AMPHIBIAN EGG - Universitaet, Federal Republic of Germany) (COSPAR, IAU, INSIGHTS PROVIDED BY GRAVITATIONAL STUDIES International Union of Physiological Sciences, and International A. W. NEFF, J. D. RITZENTHALER, and J. F. ROSENBAUM Academy of Astronautics, Plenary Meeting and Workshops XVll (Indiana University, Bloomington) (COSPAR, IAU, International and XVlll on Life Sciences and Space Research XXlll(5) - Union of Physiological Sciences, and International Academy of Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances Astronautics, Plenary Meeting and Workshops XVll and XVlll on in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. Life Sciences and Space Research XXlll(5) - Gravitational Biology, 231 -240. refs Espoo, Finland, July 18-29, 1988) Advances in Space Research Copyright (ISSN 0273-1177), vol. 9, no. 11, 1989, p. 177-186. refs Results are presented from experiments conducted on the (Contract NAG2-323) functions of the gravity sensors in goldfish. A rotary illumination Copyright device was used to study the dorsal light response that von Holst The variability in the response of Xenopus laevis eggs to a (1935) proposed as a model for postural adjustment in fish. The given force environment is studied. The roles of cytoplasmic threshold of the gravity sensors under changes of the gravitoinertial organelle, the yolk platelets, and cytoskeletal components in varying force level produced by a linear sled is determined from postural in cytoplasmic mobility are examined. The data reveal that the adjustment responses. The light-dependent behavior of intact and packing of yolk platelets is not a major factor in causing cytoplasmic labyrinthectomized goldfish was studied under hypogravity mobility differences and microtubules may affect cytoplasmic conditions during parabolic aircraft flight. The results suggest that mobility. I.F. the valvula cerebelli is the most likely candidate for the neural center of the dorsal light response. R.B. A90-15076 FERTILIZATION OF FROG EGGS ON A SOUNDING ROCKET A90-15081 IN SPACE LIGHT MICROSCOPIC ANALYSIS OF THE GRAVIRECEPTOR G. A. UBBELS, J. NARRAWAY (Netherlands Institute for IN XENOPUS LARVAE DEVELOPED IN HYPOGRAVITY Developmental Biology, Utrecht), and W. BERENDSEN (Utrecht, W. BRIEGLEB, J. NEUBERT, A. SCHATZ, and B. KRUSE (DLR, Rijksuniversiteit, Netherlands) (COSPAR, IAU, International Union lnstitut fuer Flugmedizin, Cologne, Federal Republic of Germany) of Physiological Sciences, and International Academy of (COSPAR, IAU, International Union of Physiological Sziences, and Astronautics, Plenary Meeting and Workshops XVll and XVlll on International Academy of Astronautics, Plenary Metkg and Life Sciences and Space Research XXlll(5) - Gravitational Biology, Workshops XVll and XVlll on Life Sciences and Space Research Espoo, Finland, July 18-29, 1988) Advances in Space Research XXlll(5) - Gravitational Biology, Espoo, Finland, July 18-29, 1988)

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Advances in Space Research (ISSN 0273- 177), vol. 9, no. 11, Life Sciences and Space Research XXlll(5) - Gravitational Biology, 1989, p. 241-244. refs Espoo, Finland, July 18-29, 1988) Advances in Space Research Copyright (ISSN 0273-1177)' vol. 9, no. 11, 1989, p. 273-281. refs The effect of hypogravity on the early differentiation of gravity Copyright receptors in the vestibular endorgan of Xenopus embryos and This paper reviews the important effects of gravity and young larvae developed on ground or aboard a spacecraft (D1 microgravity on biological systems and examines basic mechanisms Spacelab Shuttle Mission) were investigated using light-microscope of these effects. The effect of microgravity on convection, (which and TEM analyses. It was found that the expression of crystals in is known to be drastically reduced in space) as a possible major the saccus endolymphaticus was statistically greater in the Xenopus mechanism is discussed. Model simulations of microgravity embryos developed in hypogravity than it was in the embryos condition are presented. Particular attention is given to a developed on ground. IS. comparison of clinostat and microgravity conditions for gravitropical systems of plants which can show sustained oscillations. It is A90-15082' University of Southern Illinois, Carbondale. suggested that microgravity may affect the coupling between THE BIOLOGICAL CLOCK OF NEUROSPORA IN A individual oscillators in a multioscillatory system. IS. MICROGRAVITY ENVIRONMENT JAMES S. FERRARO (Southern Illinois University, Carbondale, IL), CHARLES A. FULLER (California, University, Davis), and FRANK A90-15085' California Univ., Davis. M. SULZMAN (NASA, Div. of Life Sciences, Washington, DC) GRAVITATIONAL BIOLOGY AND THE MAMMALIAN (COSPAR, IAU, International Union of Physiological Sciences, and CIRCADIAN TIMING SYSTEM International Academy of Astronautics, Plenary Meeting and CHARLES A. FULLER, DEAN M. MURAKAMI (California, University, Workshops XVll and XVlll on Life Sciences and Space Research Davis), and FRANK M. SULZMAN (NASA, Div. of Life Sciences, XXlIl(5) - Gravitational Biology, Espoo, Finland, July 18-29, 1988) Washington, DC) (COSPAR, IAU, International Union of Advances in Space Research (ISSN 0273-1177), vol. 9, no. 11, Physiological Sciences, and International Academy of Astronautics, 1989, p. 251-260. refs Plenary Meeting and Workshops XVll and XVlll on Life Sciences (Contract NAG2-361; NAG2-452 NAG2-349; NAS9-15975) and Space Research XXlll(5) - Gravitational Biology, Espoo, Copyright Finland, July 18-29, 1988) Advances in Space Research (ISSN The effects of simulated microgravity (via the use of a slowly 0273-1177), vol. 9, no. 11, 1989, p. 283-292. refs rotating clinostat), altered orientation (via alterations in the vector (Contract NAS2-12334; NAG2-349) of a 1-g force), and hypergravity (via centrifugation) on the circadian Copyright rhythm of conidiation in Neurospora crassa were investigated. It Using published reports, this paper compares and contrasts was found that the clinostat, while capable of producing some of results on the effects of altered gravitational fields on the regulation the microgravity effects seen in space (Sulzman, 1984), did not in mammals of several physiological and behavioral variables with produce major repeatable results. Similarly, alterations of the vector the circadian regulation of the same variables. The variables of a 1-g gravity load were not adequate simulations of space considered include the temperature regulation, heart rate, activity, flight on the conidiation rhythm. The results on the acute and food intake, and calcium balance. It is shown that, in rats, the chronic exposures to hypergravity demonstrated that chronic homeostatic regulation of the body temperature, heart rate, and exposure of Neurospora to a 3-9 force had no damping effect. activity becomes depressed following exposure to a 2 G On the other hand, an acute 10-min exposure to this hypergravity hyperdynamic field, and recovers within 6 days of 1 G condition. (the lift-off conditions) was found to cause significant damping on In addition, the circadian rhythms of these variables exhibit a the circadian rhythm of conidiation. This effect was eliminated by depression of the rhythm amplitude; a recovery of this condition a brief light pulse given 36 hrs after the exposure to 3 g. I.S. requires a minimum of 7 days. IS.

A90-15083 Hamburg Univ. (Germany, F.R.). THE EXPRESSION OF A CIRCADIAN RHYTHM IN TWO A90-15438' National Aeronautics and Space Administration. STRAINS OF CHLAMYDOMONAS RElNHARDll IN SPACE Ames Research Center, Moffett Field, CA. DIETER MERGENHAGEN and ELKE MERGENHAGEN (Hamburg, EFFECT OF IODINE DISINFECTION PRODUCTS ON HIGHER Universitaet, Federal Republic of Germany) (COSPAR, IAU, PLANTS International Union of Physiological Sciences, and International D. JANIK, B. MACLER. R. D. MACELROY (NASA, Ames Research Academy of Astronautics, Plenary Meeting and Workshops XVll Center, Moffett Field, CA), Y. THORSTENSON (California, and XVlll on Life Sciences and Space Research XXlll(5) - University, Berkeley), and R. SAUER (NASA, Johnson Space Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances Center, Houston, TX) (COSPAR, Plenary Meeting, 27th, Topical in Space Research (ISSN 0273-1 177), vol. 9, no. 11, 1989, p. Meetings on Life Sciences and Space Research XXlll(3): Natural 261-270. Research supported by BMFT, ESA, and NASA. and Artificial Ecosystems, Espoo, Finland, July 18-29, 1988) Copyright Advances in Space Research (ISSN 0273-1177), vol. 9, no. 8, The effect of microgravity on the circadian rhythm of 1989, p. 117-120. refs Chlamydomonas was investigated in two strains flown on the D1 Copyright mission: a wild-type strain with a circadian period of 25-26 hrs Iodine is used to disinfect potable water on United States and a mutant strain with a 18-20-hr rhythm. The parameter used spacecraft. Iodinated potable water will likely be used to grow as a measure of the circadian oscillation was the accumulation plants in space. Little is known about the effects of iodine rate of cells in an illuminated area of the test cuvette, which was disinfection products on plants. Seeds of select higher plants were measured by photocells. The endogenous circadian rhythm of the germinated in water iodinated using the Shuttle Microbial Check photoaccumulation response of cells was found to persist in both Valve, and water to which measured amounts of iodine was added. strains. However, the amplitude was about twice as high in space Percent germination was decreased in seeds of most species as on the ground, indicating that a larger fraction of cells was germinated in iodinated water. Beans were most affected. able to contribute to the expression of the rhythm in space. IS. Germination rates, determined from germination half-times, were decreased for beans germinated in iodinated water, and water to A90-15084 which iodide was added. Development was retarded and rootlets RHYTHMIC BIOLOGICAL SYSTEMS UNDER MICRO4 were conspicuously absent in bean and several other plant species CONDITIONS germinated in iodinated water. Iodide alone did not elicit these A. JOHNSSON and T. EIDESMO (Allmennvitenskapelige responses. Clearly iodine disinfection products can affect higher Hogskolen, Trondheim, Norway) (COSPAR, IAU, International plants. These effects must be carefully considered for plant Union of Physiological Sciences, and International Academy of experimentation and cultivation in space, and in design and testing Astronautics, Plenary Meeting and Workshops XVll and XVlll on of closed environmental life support systems. Author

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A90-15440' National Aeronautics and Space Administration. Edmonton, Canada) and W. S. C. BROOKS (SED Systems, Inc., Ames Research Center, Moffett Field, CA. Saskatoon, Canada) (COSPAR, Plenary Meeting, 27th, Topical PRODUCTIVITY AND FOOD VALUE OF AMARANTHUS Meetings on Life Sciences and Space Research XXlll(3): Natural CRUENTUS UNDER NON-LETHAL SALT and Artificial Ecosystems, Espoo, Finland, July 18-29, 1988) BRUCE A. MACLER and ROBERT D. MACELROY (NASA, Ames Advances in Space Research (ISSN 0273-1177), vol. 9, no. 8, Research, Center, Moffett Field, CA) (COSPAR, Plenary Meeting, 1989, p. 179-184. 27th, Topical Meetings on Life Sciences and Space Research Copyright XXlll(3): Natural and Artificial Ecosystems, Espoo, Finland, July The effects of low gravity, as produced by a reduced gravity 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. aircraft, the KC135, on the formation and coalescence of gas 9, no. 8, 1989, p. 135-139. Research supported by the US. National bubbles were examined over a range of gas-liquid ratios and with Research Council. refs various medium constituents. These effects will influence design Copyright considerations of fermentors operating in reduced gravity Experiments were carried out to analyze the effects of conditions. Author increasing salinity stress on growth, photosynthesis, and carbon allocation in the crop plant Amaranthus. Plants were germinated A90-15478' National Aeronautics and Space Administration. and grown in Hoagland's solution with NaCl concentrations of 0 Ames Research Center, Moffett Field, CA. to 1.O percent. The limits of total salinity in the plant growth medium THE LIFE SCIENCES PROGRAM AT THE NASA AMES are investigated. For Amaranthus cruentus, germination, vegetative RESEARCH CENTER - AN OVERVIEW growth, flowering, seed development and yield were normal at JOAN VERNIKOS-DANELLIS and JOSEPH C. SHARP (NASA, salinities from 0 to 0.2 percent. Inhibition of these phases increased Ames Research Center, Moffett Field, CA) (International Union from 0.2 to 0.4 percent salinity and was total above 0.5 percent of Physiological Sciences Commission on Gravitational Physiology, with 1 percent salinity was lethal to all developmental phases. Annual Meeting, loth, Montreal, Canada, Oct. 9-14, 1988) Onset of growth phases were not affected by salinity. Plants could Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. 1989, not be adapted by gradually increasing salinity over days or weeks. p. S-1 to S-4. refs Water uptake increased, while photosynthetic C02 uptake Copyright decreased with increasing salinity on a dry weight basis during The research projects planned for the Life Sciences program vegetative growth. Protein levels were unchanged with increasing have a goal of answering basic questions concerning the nature salinity. Leaf starch levels were lower at salinities of 0.5 percent of life itself and its evolution in the universe from basic elements, and above, while stem starch levels were not affected by these as well as the search for extraterrestrial intelligence. The program salinities. The evidence supports salt inhibition arising frm changes also includes studies of the evolution and development of life on in primary biochemical processes rather than from effects on water the planet earth, and the global changes occurring today that relations. While not addressing the toxic effects of specific ions, it affect life on the earth. The paper describes the simulation models suggests that moderate salinity per se need not be a problem in developed to study the effects of space, the flight projects of the space systems. C.E. program, and the biomedical program, which currently focuses on the physiological changes in the human body that are associated A90-15442 with space flights and the interactions among these changes. CARBON CYCLING BY CELLULOSE-FERMENTING I.S. NITROGEN-FIXING BACTERIA S. B. LESCHINE and E. CANALE-PAROLA (Massachusetts, University, Amherst) (COSPAR, Plenary Meeting, 27th, Topical A90-15479 Meetings on Life Sciences and Space Research XXlll(3): Natural PERIODIC ACCELERATION STIMULATION IN A and Artificial Ecosystems, Espoo, Finland, July 18-29, 1988) WEIGHTLESSNESS ENVIRONMENT (PAS-WE) - A NEW Advances in Space Research (ISSN 0273-1177), vol. 9, no. 8, SCIENCE? 1989, p. 149-152. refs RUSSELL R. BURTON (USAF, School of Aerospace Medicine, (Contract NSF BSR-87-08469; DE-FG02-88ER-13898) Brooks AFB, TX) (International Union of Physiological Sciences Copyright Commission on Gravitational Physiology, Annual Meeting, loth, The most abundant organic materials on earth are plant Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN polysaccharides such as cellulose and hemicelluloses. Inasmuch 0031-9376), vol. 32, Feb. 1989, p. S-5to S-7. refs as vast quantities of these polymers are present in anaerobic Copyright environments (e.g., in soils and sediments), anaerobic This paper examines the possibility of applying periodic microorganisms that ferment plant polysaccharides play a central acceleration to stimulate physiological processes affected in a role in carbon cycling on the planet as a source of C02 and, human body by the exposure to weightlessness. While it is known indirectly, of CH4. Cellulose-fermentingbacteria from soil and pond that a continuous exposure of animals to increased G may result sediment were isolated in a medium (incubated in N2) which lacked in a disease of stress (the so-called 'chronic acceleration sickness'), a source of combined nitrogen. The isolates had the ability to the risk of the chronic acceleraltion sickness can be greatly reduced utilize atmospheric N2 as the nitrogen source for cell growth. by adapting the animals by either slowly increasing the levels of Nitrogenase (the enzyme which catalyzes the reduction of N2 to G over a series of several week-long exposures or by applying ammonia) was demonstrated by means of the acetylene reduction short-duration daily exposures at the desired level of G. This paper test in these isolates and in several previously described anaerobic outlines in detail procedures for an experimental study with human cellulolytic bacteria isolated from various natural environments. subjects where this latter type of adaptation regimen is used in Thus, cellulose-fermentingbacteria that fix N2 may be widespread conjunction with the bedrest to determine the optimal schedule of and may play a role in nitrogen cycling as well as in carbon G exposures for stimulating all physiological parameters known to cycling on a global scale. Knowledge of the physiology and ecology be affected by weightlessness. Preliminary results of a G-tolerance of these organisms is crucial to detailing the mechanisms producing study are presented. IS. local sources and sinks of atmospheric gases, interpreting data obtained using space-based sensors, and understanding the effects AS15482 of atmospheric warming on fermentations as major sources of CHANGES IN KIDNEY RESPONSE TO ADH UNDER C02 and CH4 Author HYPOGRAVITY - RAT MODELS AND POSSIBLE MECHANISMS L. N. IVANOVA, A. 1. GRIGOR'EV, N. N. MELIDI, and E. 1. AS15446 SOLENOV (AN SSSR, lnstitut Tsitologii i Genetiki, Novosibirsk; GAS BUBBLE COALESCENCE IN REDUCED GRAVITY lnstitut Mediko-Biologicheskikh Problem, Moscow, USSR) CONDITIONS (International Union of Physiological Sciences Commission on B. G. THOMPSON (Alberta Research Council, Biotechnoloy Dept., Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada,

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Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. rats exposed to 12.5 days of flight aboard Cosmos 1887 or to 32, Feb. 1989, p. S-16 to S-18. refs seven days of tail suspension, respectively. The flight-exposed Copyright rats were adapted to normal gravity for over 50 hrs prior to sacrifice Mechanisms involved in the response of the kidney water/salt and tissue harvesting. In the experiments with flight-exposed rats, metabolism to ADH in hypogravity were investigated in homozygous swelling pressures were 690, 675, and 622 mm Hg for flight rats, and heterozygous (HZ) rats exposed to space flights. In HZ rats synchronous controls, and vivarium controls, respectively. In the secretion of ADH was suppressed by free access to a 4-percent experiments with simulated weightlessness, swelling pressures sucrose solution. Estimates of the ADH response were based on were 295, 610, and 527 mm Hg for tail-suspended rats, cage an increase in urine osmolality produced by an injection of synthetic controls, and vivarium controls, respectively, suggesting that fluid arginine-vasopressin. The results obtained suggest that changes moves into the disc during seven days of simulated in the intrarenal osmotic gradients and in the aggregate state of weightlessness. IS. the ADH receptors that take place as a result of the decreased ADH blood level due to hypogravity might be the cause of the A90-15486 inadequate response to ADH, observed in space-crew members NORMALISATION OF BONE CELLULAR RESPONSES during readaptation to the earth's gravity. IS. OCCURS BETWEEN 7 AND 14 DAYS OF SIMULATED WEIGHTLESSNESS IN RATS A90-15483 L. VlCO and C. ALEXANDRE (Saint-Etienne, Universite, France) THE EFFECT OF SUSPENSION ON NICOTINIC (International Union of Physiological Sciences Commission on RECEPTOR NUMBER AND AFFINITY AT Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada, THE RAT NEUROMUSCULAR JUNCTION Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. JOYCE E. ROYLAND and L. J. WEBER (Oregon State University, 32, Feb. 1989, p. S-25, S-26. Research supported by DRET. Newport) (International Union of Physiological Sciences refs Commission on Gravitational Physiology, Annual Meeting, 1Oth, Copyright Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN Wistar rats were exposed to simulated weightlessness by being 0031-9376), vol. 32, Feb. 1989, p. S-19, S-20. refs subjected to tail suspension for 7 days or 14 days, and the results Copyright of a histomorphometric analysis on tibial proximal methaphyses Mechanisms involved in the post-spaceflight muscle atrophy from these rats were compared. It was found that the longitudinal were investigated in rats subjected to tail suspension for one, bone growth was depressed twofold greater in rats exposed to a three, or eight weeks. The number of nicotinic acetylcholine 14-day suspension than in those after 7-day suspension. At the receptors (Bmax) and the receptor affinity constant (Kd) were level of the primary spongiosa, the depressed longitudinal bone examined in the unloaded phasic gastrocnemius and tibialis anterior growth rate was associated with decreased trabecular bone volume and the tonic soleus, as well as the loaded plastic triceps for rats exposed to 7-day suspension and with decreased trabecular brachii, using a specific nicotinic-acetylcholine-receptor ligand, thickness in both groups of rats. At the level of the secondary alpha-bungarotoxin. It was found that, compared to unsuspended spongiosa, the 7-day suspended rats were more affected than controls, the Kd value was significantly decreased only in the the 14-day suspended rats, indicating a more severe disequilibrium soleus after three weeks of suspension. The Bmax value was in the bone cell population of rats exposed to only 7-day-long tail increased in the triceps brachii after three weeks of suspension suspension. IS. and in the gastrocnemius after an eight-week suspension. I.S. A90-15487 A90-15484 MODIFICATIONS OF BONE ATROPHY SEEN WITH HINDLIMB BIOCHEMICAL AND HISTOCHEMICAL OBSERVATIONS OF SUSPENSION BY EXERCISE AND DOBUTAMINE VASTUS MEDIALIS FROM RATS FLOWN IN COSMOS 1887 S. BLOOMFIELD, B. GIRTEN, S. WEISBRODE, E. EVELAND, and (EXPERIMENT K608) L. KAZARIAN (Ohio State University, Columbus; USAF, Aerospace X. J. MUSACCHIA, J. M. STEFFEN, and R. FELL (Louisville, Medicine Research Laboratory, Wright-Patterson AFB, OH) University, KY) (International Union of Physiological Sciences (International Union of Physiological Sciences Commission on Commission on Gravitational Physiology, Annual Meeting, 1Oth, Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 00314376). vol. 32, Feb. 1989, p. S-21,S-22. refs 32, Feb. 1989, p. S-27,S-28. Copyright (Contract AF PROJECT 2312V6) Biochemical, histochemical, and metabolic changes affected in Copyright the vastus medialis (VM) of rats by a 12 day-long space flight The effects of an endurance-training or treatment were investigated. Results indicated that the exposure to on the microgravity-induced bone atrophy were investigated in rats microgravity for 12 days led to a decrease in the fiber area of the assigned to either 11 weeks of exercise training or sedentary muscle and decreases in the concentration of RNA and the activity conditions. Animals from both groups were then randomly assigned of lactate dehydrogenase, compared with ground controls. Protein to either hind-limb suspension or control groups, and half of each concentrations in the VM of space-flight exposed rats were similar group was treated with dopamine. It was found that 14 days of to those of controls. IS. hind-limb suspension produced significant decreases in cortical bone area, resulting at least in part from a decreased formation A90-15485' National Aeronautics and Space Administration. at the periosteal surface. The vigorous training protocol followed Ames Research Center, Moffett Field, CA. in this study also produced a net loss of bone in nonsuspended DECREASED SWELLING PRESSURE OF RAT NUCLEUS rats, but appeared to maintain bone area in suspended trained PULPOSUS ASSOCIATED WITH SIMULATED rats (the former effect, however, might be explained by a significant WEIGHTLESSNESS loss of body weight in trained rats). Dobutamine did effectively ALAN R. HARGENS and MUBASHAR MAHMOOD (NASA, Ames prevent the loss of cortical bone due to suspension in nontrained Research Center, Moffett Field; California, University, La Jolla) rats. In trained rats, however, dobutamine appeared to counteract (International Union of Physiological Sciences Commission on the maintenance of bone. IS. Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. A90-15488 32, Feb. 1989, p. S-23, S-24. Research supported by the Cosmos THE EFFECT OF MICROGRAVITY ON THE REPRODUCTIVE 1887 Rodent Parts Program. refs FUNCTION OF MALE RATS Copyright L. V. SEROVA, L. A. DENISOVA, and 0. V. BAIKOVA (Institut Data are presented on the effects of actual and simulated Mediko-Biologicheskikh Problem, Moscow, USSR) (International weightlessness on the swelling pressure of nucleus pulposus in Union of Physiological Sciences Commission on Gravitational

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Physiology, Annual Meeting, 10th. Montreal, Canada, Oct. 9-14, 0031-9376), vol. 32, Feb. 1989, p. S-45 to S-48. refs 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. Copyright 1989, p. S-29, S-30. refs The effects of microgravity on the vestibular functions, motor Copyright control, and cardiovascular systems of primates are examined. The effect of a 14-day tail suspension on the condition of the Gaze fixation reaction data reveal that under microgravity male-rat reproductive system was investigated and compared with hypermetria occurs. The movement amplitude fluctuates around the effect of a 7-day flight aboard Cosmos-1667. It was found 40 deg before the flight and in flight increases steadily peaking that, while the space flight had no effects on either the testis on the 6th day of flight; an increase in saccade velocity is also tissue, spermatozoa, or off springs of flight males, the tail-suspended detected. The vestibular nerve fibers responses to canal and visual rats exhibited a reduction of the testis and epididymis mass and a stimulation are studied. It is observed that the transition to sharp fall in the spermatozoa number; many cells, particularly microgravity results in distinct alteration of neuronal dynamic spermatides, were found in different stages of degeneration. It is sensitivity. It is concluded that canal and otolithic stimuli in suggested that the cause for the changes observed in microgravity result in the increase in dynamic stability of the tail-suspended rats was related to an anatomical dislocation of vestibular system. I.F. the organs due to the shift into the abdominal cavity, resulting in depressed spermatogenesis. I.S. A90-15497 CONTINUING STUDIES OF 'CELLS FLIGHT HARDWARE A90-15489' Emory Univ., Atlanta, GA. J. DUKE, J. MOORE, and D. MONTUFAR-SOLIS (Texas, University, PLASMA STRESS HORMONES IN RESTING RATS - EIGHTY Houston) (International Union of Physiological Sciences FOUR DAY STUDY Commission on Gravitational Physiology, Annual Meeting, 1Oth, VOJIN POPOVIC and CLEGG HONEYCUTT (Emory University, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN Atlanta, GA) (International Union of Physiological Sciences 0031-9376), vol. 32, Feb. 1989, p. S-57, S-58. refs Commission on Gravitational Physiology, Annual Meeting, 1Oth, Copyright Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN This paper describes the features of the ESA's Biorack, a 0031-9376), vol. 32, Feb. 1989, p. S-31, S-32. refs modular cell culture facility designed for the Spacelab, which will (Contract NAS2-10527) make it possible to study on the cellular level the effects of a Copyright spaceflight and weightlessness separately. Also described are The effects of a repeated mild stress of handling and placing preliminary studies for an experiment (CELLS) which was selected rats temporarily into unfamiliar cages on the blood-plasma as a Biorack experiment. Biorack contains a freezer; a cooler; a concentration of the stress hormones (corticosterone, ACDH. and glovebox; and two incubators, each with a 1-g centrifuge, making prolactin) were investigated in male Sprague-Dawley rats subjected it possible to separate the results of the spaceflight from those of to this type of stress once every week during a period of three microgravity. In the CELLS experiment, small high-density cultures months. Results showed that repeated mild stress of handling (as of embryonic limb mesenchymal cells will be exposed to well as repeated blood sampling) did not affect the plasma microgravity aboard the spacecraft, fixed daily during the mission, stress-hormone concentrations in these animals. IS. and examined on return for any effects of microgravity on cartilage differentiation. IS.

A90-15491' Arizona Univ., Tucson. A90-15498 EFFECTS OF SIMULATED WEIGHTLESSNESS AND SKELETAL MUSCLE ANTIOXIDANT ENZYME LEVELS IN SYMPATHECTOMY ON MAXIMUM V02 OF MALE RATS RATS AFTER SIMULATED WEIGHTLESSNESS, EXERCISE C. R. WOODMAN, C. S. STUMP, S. M. BEAULIEU, 2. RAHMAN, AND DOBUTAMINE L. A. SEBASTIAN (Arizona, University, Tucson) et al. (International B. GIRTEN, C. OLOFF, P. PLATO, E. EVELAND, A. J. MEROLA Union of Physiological Sciences Commission on Gravitational (USAF, Aerospace Medical Research Laboratory, Wright-Patterson Physiology, Annual Meeting, loth, Montreal, Canada, Oct. 9-14, AFB; Ohio State University, Columbus) et al. (International Union 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. of Physiological Sciences Commission on Gravitational Physiology, 1989, p. S-35,S-36. refs Annual Meeting, 1Oth, Montreal, Canada, Oct. 9-14, 1988) (Contract NAS2-392) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. 1989, Copyright p. S-59, S-60. refs The effects of simulated weightlessness (hind-limb suspension) (Contract AF PROJECT 2312V6) and chemical sympathectomy (by repeated injections with Copyright guanethidine sulfate) on the maximum oxygen consumption 0102 The effects of exercise training of rats prior to a 14-day-long max) of female rats were investigated in rats assigned for 14 hypokinesialhypokynamia (H/H) hind-limb suspension, and of days to one of three groups: a head-down hind-limb suspension, dobutamine injections during the suspension, on the levels of a horizontal suspension with hind limbs weight bearing, or the oxidative and antioxidant enzymes in skeletal muscles of the caged control. The V02 max values were assessed by having animals were investigated. The results obtained demonstrated that rats run on a treadmill enclosed in an airtight chamber. The the H/H suspension of rats resulted in decreased oxidative-enzyme hind-limb-suspended sympathectomized rats were found to exhibit levels as well as in the decreased activity of two antioxidant shorter run times and lower mechanical efficiencies, compared to enzymes that are necessary to prevent uncontrolled free-radical their presuspension values or the values from saline-injected reactions that cause tissue damage. It was found that both the suspended controls. On the other hand, the suspended exercise training and the injections of dobutamine helped to prevent sympathectomized rats did not demonstrate a decrease in the large decreases of these enzymes. I.S. V02 max values that was observed in saline-injected controls. IS. A90-15499' California Univ., Davis. TEMPERATURE REGULATION IN RATS EXPOSED TO A 2 G A90-15494 FIELD STUDIES OF SPACE ADAPTATION SYNDROME IN LINDA M. ISHIHAMA, DEAN M. MURAKAMI, and CHARLES A. EXPERIMENTS ON PRIMATES PERFORMED ON BOARD OF FULLER (California, University, Davis) (International Union of SOVIET BIOSATELLITE 'COSMOS-1887' Physiological Sciences Commission on Gravitational Physiology, 1. B. KOZLOVSKAIA, E. A. IL'IN, M. G. SIROTA, V. I. KOROL'LKOV, Annual Meeting, loth, Montreal, Canada, Oct. 9-14, 1988) B. M. BABAEV (Institut Mediko-Biologicheskikh Problem, Moscow, Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. 1989, USSR) et al. (International Union of Physiological Sciences p. S-61, S-62. Commission on Gravitational Physiology, Annual Meeting, 1Oth, (Contract NAG2-349) Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN Copyright

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The regulation of body temperature involves both homeostatic with an alpha-amino acid was investigated in experiments with and circadian control systems. Both systems are influenced by rats and mice irradiated with doses of 5 and 8.5 Gy, respectively. exposure to hyperdynamic fields and demonstrate acute responses The extent of radioprotection was assessed using hematological that eventually recover to an adapted level. This experiment indices, the values of the erythrocyte and leukocyte examined both the homeostatic and circadian responses of body electroconductivity, the average lifetime of the animal, and the temperature to a separate environmental challenge (high frequency survival rate. Results showed that the preparation could be either light/dark cycles) during exposure to a 2 G hyperdynamic field. therapeutic or protective depending on the animal species and Author the radiation dose. IS.

A90-15500 EFFECT OF INCREASED ACCELERATION ON LUNG EXPANSION IN DOGS - PRONE VS. SUPINE BODY A90-15635 POSITIONS RADIOPROTECTIVE EFFECTS OF ATP AND ADP ON S. J. LAI-FOOK, L. V. BROWN, S. GANESAN, V. S. MAUDGALYA, MEMBRANE-BOUND ENZYMES and C. F. KNAPP (Kentucky, University, Lexington) (International [RADIOMODIFITSIRUIUSHCHEE DEISTVIE ATF I ADF NA Union of Physiological Sciences Commission on Gravitational MEMBRANOSVIAZANNYE FERMENTY] Physiology, Annual Meeting, 1Oth, Montreal, Canada, Oct. 9-14, K. SH. NADAREISHVILI, D. V. CHIKVASHVILI, and M. G. BERIDZE 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. (AN GSSR, lnstitut Fiziologii, Tbilisi, Georgian SSR) Radiobiologiia 1989, p. S-63, 5-64. refs (ISSN 003343192), vol. 29, Sept.-Oct. 1989, p. 648-651. In (Contract NIH-HL-36597) Russian. refs Copyright Copyright The effect of body position on the extent of lung expansion The radioprotective effects of ATP and ADP (1 mM/kg injected under increased acceleration was investigated in dogs positioned 15 min before irradiation) on the activity of some key in a centrifuge in such a way that, between 2G and 3G centrifugal membrane-bound enzymes, including microsomal Na,K-ATPase, acceleration, the resultant force due to acceleration was in a Ca(2+)-ATPase, and n-nitrophenylphosphatase and mitochondrial direction either ventral-to-dorsal (+Gx, supine position) or Mg(2+)-ATPase and HCOd(-)-ATPase, in the brain and heart dorsal-to-ventral (-Gx, prone position). To assess the extent of tissues of rats irradiated at a dose of 7 Gy (1.125 Gylmin) were lung expansion, the pleural liquid pressure under increased investigated. The results confirmed previous reports concerning acceleration in prone and supine body positions was measured the radioprotectiveaction of ADP. The reactions of various enzymes using the rib capsule technique described by Weiner-Kronish et to irradiation and to both phosphates were found to vary, the 81. (1985). It was found that the net effect of high acceleration differences being attributed to the activity of natural compensatory was to expand the lung in the supine position and to contract the systems present in different cells and tissues. I.S. lung in the prone position. The mechanisms responsible for these effects are discussed. IS.

A90-15633 PREVENTION OF RADIATION SICKNESS, INDUCED BY A90-15636 LOW-LEVEL IONIZING RADIATION, BY REPEATED INCREASING THE RADIORESISTANCE OF MICE WITH INJECTIONS WITH INCREASING DOSES OF CHEMICAL IVASTIMUL [POWSHENIE RADlATSlONNOl USTOlCHlVOSTl RADIOPROTECTORS [PROFILAKTIKA LUCHEVOI BOLUNI, MYSHEI PRI POMOSHCHI IVASTIMULA] WZVANNOI IONlZlRUlUSHCHlM IZLUCHENIEM MALO1 D. ROTKOVSKA, A. VACEK, and A. BARTONICKOVA MOSHCHNOSTI, POVTORNOI IN’EKTSIEI (Ceskoslovenska Akademie Ved, Biofysikalni Ustav, Brno, VOZRASTAIUSHCHIKH DOZIROVOK KHlMlCHESKlKH Czechoslovakia) Radiobiologiia (ISSN 0033-8192), vol. 29, RADIOPROTEKTOROV] Sept.-Oct. 1989, p. 652-654. In Russian. refs V. S. BARKAIA, R. A. TORUA, and ZH. V. ELISTRATOVA (AMN Copyright SSSR, Nauchno-lssledovatel’skii lnstitut Eksperimental‘noi Patologii The radioprotective effect of a lyophilized preparation from i Terapii, Sukhumi, Georgian SSR) Radiobiologiia (ISSN unicellular algae of the chlorella type, termed ivastimul (IS), was 0033-8192), vol. 29, Sept.-Oct. 1989, p. 638-643. In Russian. investigated in mice irradiated by gamma rays (Co-60, 20 min at refs 0.43 Gy/min or 5 hr at 0.05 Gy/min), using the survival rate and Copyright hematological indices as parameters of radioprotection. Results The feasibility of protecting mice, Guinea pigs, and monkeys indicated that, at lethal doses, the IS preparation injected 24 hours from radiation sickness induced by irradiation with gamma rays prior to irradiation at a dose 800 mg/kg acted as a protector, from Cs-137 (16-25.5 hrs at the dose 0.0079-0.0094 Gylmin) with increasing significantly the survival rate of animals. At sublethal chemical radioprotectors was demonstrated by administering a doses, IS was found to speed up the restoration of cell populations combination containing sodium nitrite, cystaphos, and mexamine in the bone marrow and spleen. IS. to irradiated animals. Data are presented on clinical observations, the condition of blood-forming and intestinal issues, and survival of animals treated with repeated injections of these chemicals in low or high doses. It is shown that repeated injections of this A90-15637 mixture helped to maintain reserves of actively dividing cells in ACCUMULATION OF THE BIOLOGICAL EFFECTS OF the bone marrow, spleen, and intestine. IS. MICROWAVES AS DISPLAYED IN THE BEHAVIOR, THE PHYSICAL EFFICIENCY, THE BODY-MASS INCREASE, AND A90-15634 THE CONDITION OF CEREBRAL [KUMULIATSIIA RADIOPROTECTIVE PROPERTIES OF A CO(lll) BIOCOMPLEX BlOLOGlCHESKlKH EFFEKTOV MIKROVOLN I EE [IZUCHENIE RADIOZASHCHITNYKH SVOISTV OTRAZHENIE V POVEDENII, RABOTOSPOSOBNOSTI, BIOKOMPLEKSA CO/lIl/] PRIROSTE MASSY TELA I SOSTOlANll NEIRONOV IU. N. ISLAMOV, A. B. AKBAROV, P. A. KHAKIMOV, N. KH. GOLOVNOGO MOZGA] SHADIEVA, and M. N. ISLAMOV (Sredneaziatskii Meditsinskii N. 8. SUVOROV, M. V. MEDVEDEVA, N. N. VASILEVSKII, V. V. Pediatricheskii Institut, Tashkent, Uzbek SSR) Radiobiologiia (ISSN UR’IASH, and ZH. G. ALEKSANDROVA (AMN SSSR, @033-8192), vol. 29, Sept.-Oct. 1989, p. 644-647. In Russian. Nauchno-Issledovatel’skii lnstitut Eksperimental’noi Meditsiny, refs Leningrad, USSR) Radiobiologiia (ISSN 0033-8192), vol. 29, Copyright Sept.-Oct. 1989, p. 660-666, In Russian. refs The radioprotective potency of a of Co(lll) Copyright

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A90-15638 microdosimetric analysis of radiation-induced effects, and the CHARACTERISTICS OF THE RESPONSE OF ANIMALS biophysical interpretation of hadron effects. Special consideration BELONGING TO VARIOUS TYPOLOGICAL GROUPS TO is given to the characteristics of cosmic rays affecting space crews; HIGH-FREQUENCY AND MICROWAVE ELECTROMAGNETIC simulating the effects of cosmic rays at ground sources and on RADIATION [OSOBENNOSTI REAKTSll ZHIVOTNYKH biosatellites; and the biological effects of protons, heavy ions, RAZLICHNYKH TIPOLOGICHESKIKH GRUPP NA and galactic cosmic rays. A generalized kinetic model of cell VOZDEISTVIE ELEKTROMAGNITNYKH IZLUCHENII radiation damage is presented. I.S. VYSOKOCHASTOTNOGOI SVERKHVYSOKOCHASTOTNOGO DIAPAZONA] A90-16057 V. N. NIKITINA, N. 6. SUVOROV, N. A. MINKINA, and E. S. NEUROCHEMISTRY OF HIBERNATION IN MAMMALS SHAPOSHNIKOVA (Nauchno-lssledovatel'skii lnstitut Gigieny [NElROKHlMllA ZlMNEl SPlACHKl MLEKOPlTAlUSHCHlKH] Truda i Profiabolevanii; AMN SSSR, Nauchno-lssledovatel'skii NlKOLAl N. DEMIN, TAMARA KH. SHORTANOVA, and EMIRBEK lnstitut Eksperimental'noi Meditsiny, Leningrad, USSR) Z. EMIRBEKOV Leningrad, Izdatel'stvo Nauka, 1988, 137 p. In Radiobiologiia (ISSN 0033-8192), vol. 29, Sept.-Oct. 1989, p. Russian. refs 676-679. In Russian. refs Copyright Copyright Data are presented on biochemical processes active in the mammalian brain during hibernation and to role of neuromediators A90-15639 and neuromodulators in these processes. Special attention is given PREDICTING THE POSTRADIATIVE RADIOSENSITIVITY OF to the content changes of cerebral proteins, ribonucleic acids, MAMMALS AND MAN ACCORDING TO THE LD50 CRITERION low-molecular-weight nitrogen metabolites, lipids, and energy AFTER ACUTE EXTERNAL IRRADIATION [PROGNOZ substrates that take place during hibernation, and to changes that POSTLUCHEVOI RADIOCHUVSTVITEL'NOSTI take place in the membrane structures of the brain. It is emphasized MLEKOPITAIUSHCHIKH I CHELOVEKA PO KRlTERllU LD50 that the natural reversible hypobiosis during hibernation is different POSLE OSTROGO VNESHNEGO OBLUCHENIIA] from the passive torpor induced by low temperatures in G. M. AVETISOV and V. P. VOLODIN (Institut Biofiziki, Moscow, cold-blooded animals. I.S. USSR) Radiobiologiia (ISSN 0033-8192), vol. 29, Sept.-Oct. 1989, p. 686-690. In Russian. refs A90-16284" California Univ., San Francisco. Copyright ANATOMICAL STUDY OF THE FINAL COMMON PATHWAY FOR VOCALIZATION IN THE CAT A90-15640 GERT HOLSTEGE (California, University, San Francisco) Journal EFFECT OF IONIZING RADIATION ON THE BINDING OF of Comparative (ISSN 0021-9967),vol. 284, 1989, p. MUSCIMOL BY SYNAPTIC MEMBRANES OF THE RAT BRAIN 242-252. refs [DEISTVIE IONIZIRUIUSHCHEI RADlATSll NA SVIAZYVANIE (Contract NCC2-491) MUSTSIMOLA SlNAPTlCHESKlMl MEMBRANAMI MOZGA Copyright KRYSYI Results are presented of an anatomical study of the neuronal V. I. KUZNETSOV, M. M. IURINSKAIA, 0. V. KOLOMYTKIN, and pathways in the cat, via which the periaqueductal gray (PAG) I. G. AKOEV (AN SSSR, lnstitut Biologicheskoi Fiziki, Pushchino, produces excitation of motoneurons involved in vocalization. It is USSR) Radiobiologiia (ISSN 0033-8192), vol. 29, Sept.-Oct. 1989, shown that a specific cell group in the lateral part of the caudal p. 705, 706. In Russian. PAG and in the tegmentum just lateral to it projects bilaterally to Copyright the nucleus retroambiguus (NRA) in the caudal medulla oblongata. Neurons in the NRA in turn project, via a contralateral pathway A90-15641 through the ventral funiculus of the spinal cord, to the motoneuronal EFFECT OF ULTRAHIGH-DOSE IONIZING RADIATION ON THE cell groups innervating intercostal and abdominal muscles. In the CONTENT OF CATHECHOLAMINE MEDIATORS IN VARIOUS brainstem, the NRA neurons project to the motoneuronal cell REGIONS OF THE RAT BRAIN [VLIIANIE groups innervating mouth-opening and perioral muscles as well IONIZIRUIUSHCHEGO OBLUCHENIIA V SVERKHVYSOKOI as to motoneurons innervating the pharynx, soft palate, and tongue. DOZE NA SODERZHANIE KATEKHOLAMINOWKH These results indicate that the projections from PAG via NRA to MEDIATOROV V RAZLICHNYKH OTDELAKH GOLOVNOGO vocalization motoneurons form the final common pathway in MOZGA KRYS] vocalization. IS. E. N. GONCHARENKO, A. A. ORLOVSKII, S. V. ANTONOVA, and L. M. ROZHDESTVENSKII (Institut Biofiziki; Moskovskii A90-16286' Wright State Univ., Dayton, OH. Gosudarstvennyi Universitet, Moscow, USSR) Radiobiologiia 8-OH-DPAT SUPPRESSES VOMITING IN THE CAT ELICITED (ISSN 0033-8192), vol. 29, Sept.-Oct. 1989, p. 709-711. In BY MOTION, CISPLATIN OR XYLAZINE Russian. refs JAMES 6. LUCOT and GEORGE H. CRAMPTON (Wright State Copyright University, Dayton, OH) Pharmacology, and Behavior (ISSN 0091-3057), vol. 33, no. 3, 1989, p. 627-631. refs A90-16047 (Contract NCC2-229) BIOPHYSICAL PRINCIPLES OF THE EFFECTS OF COSMIC Copyright RAYS AND RADIATION FROM ACCELERATORS Vomiting was suppressed in cats pretreated with 8-OH-DPAT [BlOFlZlCHESKlE OSNOW DElSTVllA KOSMICHESKOI and then challenged with an emetic stimulus; motion, xylazine or RADlATSll I IZLUCHENII USKORlTELEl] cisplatin. The antiemetic effect is likely due to stimulation of A. M. UGOLEV, ED. Leningrad, Izdatel'stvo Nauka (Problemy postsynaptic -1 A receptors. The most parsimonious Kosrnicheskoi Biologii. Volume 60), 1989, 256 p. In Russian. No explanation is that it acts at a convergent structure, presumably individual items are abstracted in this volume. at or near the vomiting center. If so, 8-OH-DPAT may block emesis Copyright elicited by virtually any other stimulus. A supplementary experiment Results are presented on studies investigating the revealed that lorazepam suppressed motion sickness at a dose characteristics and the biological effects of high-energy cosmic that produced ataxia, but did not suppress xylazine-induced emesis. rays and radiation from heavy-particle accelerators. Attention is These results do not support the possibility that the antiemetic given to the analysis of biological experiments in space, the physical effects of 8-OH-DPAT were the result of anxiolytic activity. characteristics of the nuclear-active component of cosmic rays, Author the ultrahigh-energy component of cosmic radiation simulated by the Serpukhov proton accelerator, the biological effects of A90-16420' Stanford Univ., CA. high-energy hadrons in experiments using accelerators, the GROWTH RATE STUDY OF CANAVALIN SINGLE CRYSTALS

34 51 LIFE SCIENCES (GENERAL)

R. C. DEMATTEI and R. S. FEIGELSON (Stanford University, CA) ratio from rats exposed to 200 ppm NO2 with and without 5 percent Journal of Crystal Growth (ISSN 0022-0248), vol. 97, no. 2, Sept. C02 was 3-4 times that of non-exposed rats. More edema was 1989, p. 333-336. Research supported by NSF. refs noted with NO2 and C02 than with NO2 alone. GRA (Contract NAG8-489) Copyright N90-12151'# National Aeronautics and Space Administration. The dependence on supersaturation of the growth rate of single Ames Research Center, Moffett Field, CA. crystals of the protein canavalin is studied. In the supersaturation THE RODENT RESEARCH ANIMAL HOLDING FACILITY AS A ranges studied, the rate-limiting step for growth is best described BARRIER TO ENVIRONMENTAL CONTAMINATION by a screw dislocation mechanism associated with interface P. D. SAVAGE, JR., G. C. JAHNS, 6. P. DALTON, R. P. HOGAN, attachment kinetics. Using a In-In plot, the growth-rate data is and A. E. WRAY (General Electric Co.. Moffett Field, CA.) Sep. found to fit a predictive relationship of the form G = 0.012 x the 1989 11 p Presented at the 19th lntersociety Conference on supersaturation to the 6.66, which, together with the solubility Environmental Systems, San Diego, CA, 24-26 Jul. 1989 curves, allows the growth rate to be estimated under a variety of (NASA-TM-102237; A-89183; NAS 1.15:102237) Avail: NTlS HC conditions. S.A.V. AO3/MF A01 CSCL 06C The rodent Research Animal Holding Facility (RAHF), developed by NASA Ames Research Center (ARC) to separately A90-16532' National Aeronautics and Space Administration. house rodents in a Spacelab, was verified as a barrier to Langley Research Center, Hampton, VA. environmental contaminants during a 12-day biocompatibility test. SPACE STATION ACCOMMODATION OF LIFE SCIENCES IN Environmental contaminants considered were solid particulates, SUPPORT OF A MANNED MARS MISSION microorganisms, ammonia, and typical animal odors. The 12-day BARRY D. MEREDITH, KELLI F. WILLSHIRE, JANE A. HAGAMAN test conducted in August 1988 was designed to verify that the (NASA, Langley Research Center, Hampton, VA), and RHEA M. rodent RAHF system would adequately support and maintain animal SEDDON (NASA, Johnson Space Center, Houston, TX) IN: The specimens during normal system operations. Additional objectives case for Mars 111: Strategies for exploration - Technical. San Diego, of this test were to demonstrate that: (1) the system would capture CA, Univelt, Inc., 1989, p. 95-106. typical particulate debris produced by the animal; (2) (AAS PAPER 87-233) Copyright microorganisms would be contained; and (3) the passage of animal Results of a life science impact analysis for accommodation odors was adequately controlled. In addition, the amount of carbon to the Space Station of a manned Mars mission are discussed. In dioxide exhausted by the RAHF system was to be quantified. Of addition to addressing such issues as on-orbit vehicle assembly primary importance during the test was the demonstration that and checkout, the study also assessed the impact of a life science the RAHF would contain particles greater than 150 micrometers. research program on the station. A better understanding of the This was verified after analyzing collection plates placed under effects on the crew of long duration exposure to the hostile space exhaust air ducts and rodent cages during cage maintenance environment and to develop controls for adverse effects was the operations, e.g., waste tray and feeder changeouts. Microbiological objective. Elements and products of the life science testing identified no additional organisms in the test environment accommodation include: the identification of critical research areas; that could be traced to the RAHF. Odor containment was the outline of a research program consistent with the mission demonstrated to be less than barely detectable. Ammonia could timeframe; the quantification of resource requirements; the not be detected in the exhaust air from the RAHF system. Carbon allocation of functions to station facilities; and a determination of dioxide levels were verified to be less than 0.35 percent. Author the impact on the Space Station program and of the baseline configuration. Results indicate the need at the Space Station for two dedicated life science lab modules; a pocket lab to support a N90-12152' Lockheed Engineering and Sciences Co., 4-meter centrifuge; a quarantine module for the Mars Sample Washington, DC. Return Mission; 3.9 man-years of average crew time; and 20 USSR SPACE LIFE SCIENCES DIGEST, ISSUE 24 LYDIA RAZRAN HOOKE, ed., RONALD TEETER, ed., P. LYNN kilowatts of electrical power. C.E. DONALDSON, ed., VICTORIA GARSHNEK, ed., and JOSEPH ROWE, ed. (Library of Congress, Washington, DC.) Washington N90-12150# National Inst. of Standards and Technology, NASA Nov. 1989 112 p Gaithersburg, MD. Center for Fire Research. (Contract NASW-4292) SYNERGISTIC EFFECTS OF NITROGEN DIOXIDE AND (NASA-CR-3922(28)-lSSUE-24; NAS 1.26:3922(28)-lSSuE-24) CARBON DIOXIDE FOLLOWING ACUTE INHALATION Avail: Issuing Activity CSCL 06C EXPOSURES IN RATS This is the twenty-fourth issue of NASA's USSR Space Life BARBARA C. LEVIN, MAYA PAABO, LANE HIGHBARGER, and Sciences Digest. It contains abstracts of 39 journal papers or NANCY ELLER May 1989 45 p Presented at Society of book chapters published in Russian. In addition, reviews of two Toxicology Annual Meeting, Atlanta, GA, Feb. 1989 Sponsored recent Soviet books are translated. The abstracts in this issue in part by the Society of the Plastics Industry, Inc., New York, NY have been identified as relevant to 25 areas of space biology and (PB89-214779; NISTIR-89/4105) Avail: NTlS HC AOWMF A01 medicine: adaptation, aviation medicine, biological rhythms, CSCL 06P cardiovascular and respiratory systems, cytology, developmental All fires occurring in air produce carbon dioxide (C02). Fire biology, endocrinology, equipment and instrumentation, genetics, involving nitrogen-containing products will also generate nitrogen habitability and environment effects, hemetology, human dioxide (N02), a pulmonary irritant. In Fischer 344 male rats, the performance, immunology, life support systems, man-machine LC50 (30 minute exposure plus 14 day post-exposure observation systems, mathematical modeling, metabolism, microbiology, period) for NO2 was 200 ppm (with 95 percent confidence limits morphology, musculoskeletal system, , operational of 43 to 51 percent); whereas, the LC50 for NO2 in the presence medicine, psychology, radiobiology, and space medicine. Author of 5 percent C02 was 90 ppm (with 90 percent Confidence limits ranging from 70-120 ppm). Exposure to NO2 increased the N90-12153' Lockheed Engineering and Sciences Co., methemoglobin (MetHb) levels in the arterial blood. At the end of Washington, DC. the 30 minute exposures, the MetHb levels were 2-3 times higher USSR SPACE LIFE SCIENCES DIGEST, ISSUE 22 in the animals exposed to the combination of NO2 (200 ppm) and LYDIA RAZRAN HOOKE. ed., RONALD TEETER, ed., P. LYNN C02 (5 percent) than in those exposed to NO2 only. Deaths from DONALDSON, ed., VICTORIA GARSHNEK, ed., and JOSEPH NO2 were all post-exposure and occurred earlier in the presence ROWE, ed. (Library of Congress, Washington, DC.) Washington of NO2 plus 5 percent C02 than in the absence of the C02. The NASA Aug. 1989 137 p time of death was concentration-dependentwhen both gases were (Contract NASW-4292) present. At death, evidence of hemorrage and extensive edema (NASA-CR-3922(26)-lSSUE-22; NAS 1.26:3922(26)-lSSUE-22) was observed in the lungs. The mean lung wet weightlbody weight Avail: Issuing Activity CSCL 06C

35 51 LIFE SCIENCES (GENERAL)

This is the twenty-second issue of NASA's USSR Space Life organism. Future experiments can be made with this library in Sciences Digest. It contains abstracts of 56 journal papers or order to provide additional basic information on Nitrobacter's book chapters published in Russian and of a Soviet monograph genome. GRA reviewing the literature on . The complete contents of two issues of the Soviet Journal Space Biology and Aerospace N90-12156# North Carolina State Univ., Raleigh. Medicine are covered. Selected abstracts are illustrated with figures MEMBRANE FUSION: THE ROLE OF and tables from the original. A special feature presents a translation POLYPHOSPHATIDYLINOSITOL Final Report, Mar. 1986 - Mar. of an interview with two Mir cosmonauts. The abstracts in this 1989 issue have been identified as relevant to 29 areas of space biology WENDY F. BOSS and JEFFREY J. WHEELER 24 Jul. 1989 and medicine. These areas are: adaptation, biological rhythms, 5P biospherics, body fluids, botany, cardiovascular and respiratory (Contract DAAL03-86-G-0035) systems, developmental biology, endocrinology, enzymology, (AD-A211289; ARO-23767.7-LS-F) Avail: NTlS HC A02/MF A01 equipment and instrumentation, genetics, gravitational biology, CSCL 0611 habitability and environmental effects, hematology, human It was found that the presence of the phospholipid, performance, immunology, life support systems, mathematical lysophosphatidylinositol monophosphate (LPIP) correlates positively modeling, metabolism, microbiology, musculoskeletal system, with the fusion potential of fusogenic carrot cells. There was neurophysiology, nutrition, operational medicine, perception, no correlation with the presence of phosphatidylinositol psychology, radiobiology, reproductive system, and space biology monophosphate (PIP) and phosphatidylinositolbisphosphate (PIP2) and medicine. Author and fusion. Nor was there evidence for the need for PIP or PIP2 turnover in order for the cells to be fusion permissive. LPlP N90-12154' Lockheed Engineering and Sciences Co., was synthesized primarily from the phosphorylation of lyso- Washington, DC. phosphatidylinositol. Lysolipids were found to decrease the USSR SPACE LIFE SCIENCES DIGEST, ISSUE 23 phosphorylation of PI and PIP suggesting a mechanism for LYDIA RAZRAN HOOKE, ed., P. LYNN DONALDSON, ed., regulating the of the polyphosphoinositides which are RONALD TEETER, ed., VICTORIA GARSHNEK, ed., and JOSEPH key components of the pathway in many animal ROWE, ed. (Library of Congress, Washington, DC.) Washington cells. GRA NASA Aug. 1989 123 p (Contract NASW-4292) N90-12157# Duke Univ., Durham, NC. (NASA-CR-3922(27)-lSSUE-23; NAS 1.26:3922(27)-ISSUE-23) BORON ANALOGUES OF AMINO ACIDS AND DERIVATIVES Avail: Issuing Activity CSCL 06C Flnal Report, 1 Sep. 1987 - 30 Nov. 1988 This is the twenty-third issue of NASA's USSR Space Life BERNARD F. SPIELVOGEL, BARBARA RAMSAY SHAW, and Sciences Digest. It contains abstracts of 47 journal papers or ROBERT G. GHIRARDELLI 19 Jul. 1989 5 p book chapters published in Russian and of five Soviet monographs (Contract DAAL03-87-C-0029) and one book review. Selected abstracts are illustrated with figures (AD-A21131 1; ARO-25263.1-CH) Avail: NTlS HC A01 /MF A01 and tables from the original. A special feature provides a translation CSCL 06/15 of a discussion on biomedical support of manned flights to Mars. The principal goal of this research was the synthesis and The abstracts in this issue have been identified as relevant to 32 characterization of boron analogues of important biologically active areas of space biology and medicine. These areas are: adaptation, such as the amino acids. During this period of research aviation medicine, biological rhythms, biospherics, body fluids, syntheses were developed for amides of a variety of simple boron botany, cardiovascular and respiratory systems, cytology, analogues of common amino acids such as saline. Peptides developmental biology, endocrinology, enzymology, equipment and containing boron were completed. Synthetic approaches were instrumentation, gastrointestinal system, genetics, group dynamics, developed for boron analogues of phosphonates. Collaborative habitability and environmental effects, hematology, human studies on the biological activity of many of these compounds performance, immunology, life support systems, man-machine were carried out by Professor Iris H. Hall at the University of systems, mathematical modeling, metabolism, microbiology, North Carolina. Significant antitumor and hypolipidemic activity were musculoskeletal system, neurophysiology, nutrition, operational found in animal model studies. GRA medicine, perception, psychology, radiobiology, and reproductive system. Author N90-12158# California Univ., Imine. AND MEMORY FORMATION Flnal N90-12155# Cincinnati Univ., OH. Dept. of Microbiological and Technical Report, Apr. 1986 - Mar. 1989 Molecular Genetics. GARY LYNCH 30 May 1989 11 p GENETIC ENGINEERING OF ENHANCED MICROBIAL (Contract AF-AFOSR-0099-86; AF PROJ. 231 2) NITRIFICATION Environmental Research Brlet, Aug. 1983 - (AD-A211368; AFOSR-89-1141TR) Avail: NTlS HC A02/MF A01 1988 Sep. CSCL 05/8 MICHAEL CARSlOTlS and SUNIL KHANNA Jun. 1989 10 p The purpose of the proposed research was to test and (Contract EPA-CR-810888) elaborate on an hypothesis regarding cellular mechanisms (PB89-208334; EPA/600/M-89/011) Avail: NTlS HC AO2/MF responsible for storing recognition memory in mammalian A01 CSCLO6C telencephalon. The encoding process proposed involves: (1) an Experiments were conducted to introduce genetic information unusual pattern of physiological activity in the relevant neural in the form of antibiotic or mercuric ion resistance genes into pathways, (2) influx of calcium into dendritic spines postsynaptic Nitrobacter hamburgenesis strain X14. The resistance genes were to the active axons, (3) activation of the calcium-sensitive protease, either stable components of broad host range plasmids or calpain, (4) partial degradation of spectrin, a cytoskeleton protein transposable genes on plasmids presumably unable to replicate that regulates membrane surface and possibly spine in strain X14. Four methods for plasmid transformation as well as shape, and (5) anatomical reorganization of postsynaptic structure conjugation with various donor strains of Escherichia coli failed. resulting in a stable increase of postsynaptic potentials. Central The leuB gene containing DNA was restriction-mapped and the to the hypothesis is the phenomenon of long-term potentiation 1.3 kilobase pair gene was subcloned into a vector suitable for (LTP) of synaptic transmission; much of the research conducted use in DNA sequencing. To date, a tentative sequence comprising in the past three years has been aimed at characterizing the about 1300 bases was obtained. Although the primary goal of physiologicaland biochemical steps responsible for this remarkably developing a procedure for introducing genetic material into a persistent synaptic change and examining its rdQ in memory nitrifying organism is not yet achieved, the results achieved have storage. We have also hypothesized that excessive aLtivation of produced useful information on the genomic organization of the calpain system can lead to the neuronal degeneration that is Nitrobacter as well as a plasmid-borne library of genes from that associated with experimental age-related . GRA

36 52 AEROSPACE MEDICINE

N90-12159# Utah Univ., Salt Lake City. of the human to a completely artificial environment are considered, INVESTIGATION OF RESONANT AC-DC MAGNETIC FIELD as well as the demands of reintegration to the earth environment EFFECTS Flnal Report, May 1986 - Jul. 1989 upon mission completion. C.D. CARL H. DURNEY, JlRl JANATA, CATHERINE RAPPAPORT, MARK KAMINSKI, and CINDY BRUCKNER-LEA 10 Jul. 1989 A90-13606# 45 P BIOMEDICAL PAYLOAD OF THE FRENCHSOVIET LONG (Contract NO0014-86-K-0230; RR04108) DURATION FLIGHT - FIRST CONCLUSIONS (AD421 1612; UTEC-89-036) Avail: NTlS HC A03/MF A01 L. BRAAK, J. THOULOUSE, A. GUELL, D. VASSAUX (CNES, Paris, CSCL 06/7 France), A. D. GRIGOR’EV (Institut Mediko-Biologicheskikh Recently reported ObSeNatiOnS by others indicate that a Problem, Moscow, USSR) et al. IAF, International Astronautical combination of a weak dc magnetic field and extra low frequency Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 5 p. ac magnetic fields can produce resonant effects in biological (IAF PAPER 89-563) systems. The study of resonant magnetic field effects consist of The French-Soviet flight of November 26 - December 21, 1988 three parts: calculations aimed at identifying the basic mechanism enabled five biomedical experiments to be carried out, covering underlying the resonance, measurements of the effects of medical research into space. Two of them, ‘Echography’ and combined dc and ac magnetic fields on the dc current through ‘Minilab’ relate to the study of the cardiovascular system while plain (containing no channels) planar phospholipid membranes, others, ‘Physalie‘ and ‘Viminal‘, are concerned with the central and measurements of the effects of combined dc and ac magnetic nervous and sensory motor systems. The last experiment ‘Circe‘ fields on the binding of metallochromic dyes and calmodulin to covers the radioprotection area. Two ground-based experiments calcium. The calculations provided insight and a physical were added: ‘Lymphocytes‘ for studying the immune system and mechanism that explains both frequency and amplitude windows ‘Bone Densitometry‘ for studying bone mineral content. Most of in an elementary model consisting of one charged particle in a the measurements were successful and data brought back by the viscous medium. The combined dc-ac magnetic fields did affect crew were of sufficiently good quality for later scientific analysis. the dc current through planar phospholipid membranes, but not in C.E. every membrane, and not consistently at the same values of magnetic field strength and frequency. No effect of the magnetic fields were seen on the binding of metallochromic dyes and A90-13608# calmodulin to calcium. None of the measurements showed any CHANGES IN CIRCADIAN RHYTHM OF MULTIPLE resonant response like the cyclotron like resonance reported in HORMONES AND THEIR RELATIONSHIP WITH INDIVIDUAL the literature in diatoms and lymphocytes. GRA SUSCEPTIBILITY IN SIMULATED WEIGHTLESSNESS KEJIA LIU, HONGYUAN SUN, JUN LU, GUANMING ZHANG, XIAOWU PAN (Institute of Space Medico-Engineering, Beijing, People’s Republic of China) et al. IAF, International Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 9 p. refs 52 (IAF PAPER 89-565) Copyright Whether or to what extent the circadian rhythm of human urinary AEROSPACE MEDICINE melatonin (MLT), catecholamines (NE, E, and NE+E), glucocorticosteroids(1 7-OHCS, and cortisol) and cyclic nucleotides Includes physiological factors; biological effects of radiation; and (CAMP and cGMP) would be affected by a 7-day head-down tilt effects of weightlessness on man and animals. of 6 deg (HDT) was investigated using 6 male volunteers aged 21 yrs. Cosinor analysis showed that they all did exhibit profound circadian variations of the mesor, amplitude, and acrophase during A90-13267# HDT. There were also internal dissociations. A wide extent of TELESCIENCE TESTBED FOR PHYSIOLOGICAL distress was registered during HDT, and the complaints were EXPERIMENTS roughly classified into 3 ranks according to individual susceptibility. MASAMlCHl YAMASHITA (Institute of Space and Astronautical The calculation revealed that a definite correlation existed between Science, Sagamihara, Japan), SATORU WATANABE, TADAAKI endocrinal alterations and individual susceptibility. Author MANO, NOBUO MATUl (Nagoya University, Japan), FLEMMING BONDE-PETERSEN (Danish Aerospace Medical Centre of A90-13609# Research, Denmark) et al. IAF, International Astronautical UNILATERAL CENTRIFUGATION OF THE OTOLITHS AS A Congress, 4Oth, Malaga, Spain, Oct. 7-13, 1989. 12 p. NEW METHOD TO DETERMINE BILATERAL ASYMMETRIES (IAF PAPER 89-034) Copyright OF THE OTOLITH APPARATUS IN MAN A telescience system for studying human physiology was J. WETZIG, M. REISER, E. MARTIN, N. BREGENZER, and R. J. simulated using a water immersion laboratory (weightlessness VON BAUMGARTEN (Mainz, Universitaet, Federal Republic of simulator). Electrocardiography, blood pressure, skin flowmetry, Germany) IAF, InternationalAstronautical Congress, 40th, Malaga, blood analyses, and echocardiography were conducted by Spain, Oct. 7-13, 1989. 8 p. refs operators at a remote location. The quality of the data is evaluated, (Contract BMFT-01-QV-88075) and their relevance for the critical issues concerning operational (IAF PAPER 89-566) management of telescience are addressed. C.D. Ten subjects were eccentrically rotated on a Barany chair. Setting of a luminous line to subjective vertical and ocular A90-13304# counterroll (OCR) were evaluated. Subjects consistently set the THE NEXT 40 YEARS IN SPACE - ASPECTS OF HUMAN luminous line to an angle correlating to centrifugal force. Differences FACTORSINSPACERESEARCH between ’inner’ and ’outer’ eye were evident for luminous line E. BECKERS, R. KOZLOWSKI, F. NOTTELMANN, and F. PARIS settings and OCR in some subjects. There appears to exist some (Bochum, Ruhr-Universitaet, Federal Republic of Germany) IAF, agreement between asymmetries seen in setting of the line and International Astronautical Congress, 40th, Malaga, Spain, Oct. motion sickness susceptibility in parabolic flight. Author 7-13, 1989. 11 p. refs (IAF PAPER 89-091) Copyright A90-13610*# National Aeronautics and Space Administration, Problems involving the interrelation between the human being Washington, DC. and the environment occurring on long-duration space flights are LONG-TERM EXPOSURE TO ZERO-G AND THE discussed. The causes and dynamics of stress on these flights GASTRO-INTESTINAL TRACT FUNCTION are reviewed, as is the nature and limits of adaptation to PERCIAL D. MCCORMACK (NASA, Life Sciences Div., Washington, longduration space flight. The main tasks involved in the integration DC) IAF, international Astronautical Congress, 40th, Malaga,

37 52 AEROSPACE MEDICINE

Spain, Oct. 7-13, 1989. 10 p. refs light training. Statistically, the highest limit of normal BDT is equal (IAF PAPER 89-569) Copyright to 11.7 arcsec, while for specifically trained group the BDT is The gastrointestinal tract (GIT) function is described with equal to 10 arcsec. Acuteness of binocular depth vision and speed emphasis placed on its important role to smooth, delay, and modify of BDT estimation are correlated. A negative correlation between sudden fluid load stress applied to the fluid distribution control BDT and age is indicated. Illustrations of binocular depth vision system in the body. Two basic components of the GIT are under modeled space flight deconditioning include high intensity considered: stomach dynamics, which involves storage, mixing, of background illumination from 75,000 to 150,000 Ix and prismatic and discharge of food into the intestine after addition of gastric distortion by the space scafander glass. C.E. juices; and absorption of water and electrolytes from the small intestine. A dynamic model of these components is described, A90-13624# along with performance characteristics computed consecutively for A REPORT OF GROUND RESULTS FOR BRAIN FUNCTION one g and zero g conditions. The main impact of the zero g EXPERIMENTS IN SPACE condition appears to be through a change in osmotic driven LEI ME1 (Institute of Space Medico-Engineering, Beijing, People’s transport across the gut wall. A dramatic change in transport Republic of China) IAF, International Astronautical Congress, characteristics is predicted with implication for many body systems 40th, Malaga, Spain, Oct. 7-13, 1989. 6 p. refs (the immune system in particular) during long-term exposure to (IAF PAPER 89-590) Copyright zero g. Experimental measurements in zero g are needed to A new encephalofluctuograph technology (ET) for space evaluate these predictions. C.E. application has been developed. Information about super-slow activities of the brain can be abstracted from the ordinary brain AM-136 12# waves. Specific S spectral lines related to neurophysiologicaland THE BASIC HEALTH CARE SYSTEM FOR THE CREW LUNAR activities have been identified and characteristic BASE spatial patterns have been determined. ET analyses described MINORU TERAl (Tokyo Metropolitan Institute of Technology, Hino, include 20-degrees head-lowered supension experiments in rabbits; Japan) and KElJl NlTTA (National Aerospace Laboratory, Chofu, 2 G hypergravity experiments in rabbits; effects of antimotion Japan) IAF, International Astronautical Congress, 40th, Malaga, sickness drugs on rabbits during suspension; and clinical Spain, Oct. 7-13, 1989. 8 p. observations on patients with brain circulation disorders. The results (IAF PAPER 89-573) Copyright demonstrated the potential of ET application in space research. The basic health care system for the crew of the lunar base is C.E. presented, noting its two subsystems. The first is the daily health care system containing mainly the same care menu as in some biochemical and ordinary medical examinations on earth. The A90-13625# second system is a periodic medical inspection of the crew’s bones EFFECT ON THE CARDIAC FUNCTION OF REPEATED LBNP and the determination of natural radioisotopes in the body. Both DURING A ONE MONTH HEAD DOWN TILT health care systems run automatically including complete P. ARBEILLE, 0. LEBOUARD, M. MASSABUAU, J. POlTIER, F. examinations and data recordings. Examinations and data files of PATAT (Tours, Universite, France) et al. IAF, International the results are controlled by computer. Daily examinations’ results Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 4 are compared with the filed data. In case of any discrepancy, a p. Research supported by CNES. refs computerized message is sent for a close reexamination by a (IAF PAPER 89-593) Copyright medical doctor or if a recheck of the same submenu is needed. Cardiovascular assessment by ultrasound methods was The automatic health care systems and the life support monitoring performed during two long-duration head down tilt (HDT) system are kept in daily contact. C.E. experiments on 6 healthy volunteers. In a first one-month HDT session (1987), 3 of the 6 subjects had several daily lower body A90-13621# negative pressure (LBNP) test, whereas the three remaining PSYCHO-PHYSIOLOGICAL STUDIES DURING THE FLIGHT OF subjects stayed at rest without LBNP. In a second one-month THE SECOND BULGARIAN COSMONAUT HDT session (1988), the last three subjects were LBNP tested A. ALEKSANDROV and G. RADKOVSKI IAF, International and the first three were not. Different countermeasures (LBNP, Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989 isotonic or isometric exercise) have been proposed to minimize the effects of weightlessness on the cardiovascular system and 3 P. (IAF PAPER 89-586) to reduce the cardiovascular deconditioning after the flight. The Results of the psychophysiological studies carried out during decrease of the left ventricule diastolic volume and the cardiac the flight of Bulgaria’s second cosmonaut are presented and output under LBNP has been clearly demonstrated during zero g discussed. Three related experiments entitled Forecast, ground simulation. During long term flight, the LBNP test as well Investigation, and Free Time were conducted. The data were as isotonic or isometric exercise has been used intensively as a processed by two special configurations of hardware for countermeasure and a significant reduction of the cardiovascular psychophysiological research and biomedical studies. The function has been observed. The LBNP maneuver can be psychophysiological hardware configuration Pleven-87 showed high considered as an efficient countermeasure to prevent cardiac functional reliability during the experiments onboard the Mir orbital disadaptation induced by HDT position and probably microgravity. station and made possible a quantitative assessment of the C.E. cosmonauts’ mental functions during space flight. C.E. A90-13626# A90-13622# MEDICAL RESULTS OF THE FLIGHT OF THE SECOND PRIME BINOCULAR DEPTH PERCEPTION AND ITS HYPERACUITY IN CREW ON THE ORBITAL STATION MIR COMMON AND SPECIALLY SELECTED SUBJECTS 0. G. GAZENKO, A. I. GRIGORIEV, S. A. BUGROV, V. V. IGOR’ A. SHEVELEV and SVETLANA A. KOLOSOVA (AN SSSR, BOGOMOLOV, A. D. EGOROV (Institut Mediko-Biologicheskikh lnstitut Vysshei Nervnoi Deiatel’nosti i Neirofiziologii, Moscow, Problem, Moscow, USSR) et al. IAF, International Astronautical USSR) IAF, International Astronautical Congress, 40th, Malaga, Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 12 p. refs Spain, Oct. 7-13, 1989. 4 p. refs (IAF PAPER 89-594) Copyright (IAF PAPER 89-588) Copyright An analysis of the medical results of the second prime crew The differential thresholds of binocular depth (BDT) perception flown aboard the Mir station, and in particular of Yuri V. Romanenko, were studied in 542 specially selected and non-selected humans who remained in orbit for 326 days, is presented. Data are reported under usual conditions as well as under high illumination and which show that Romanenko retained good health and high work prizmatic BDT distortion. A low BDT fluctuating from 1.4 up to 36 capacity throughout the flight. This achievement is credited to arcsec is shown for specially selected observers with professional concerted efforts of the crew and mission control center, and to

38 52 AEROSPACE MEDICINE adequate environment, work-rest cycle, and countermeasures, from blood and urine samples taken before and after Space Shuttle primarily regular and active exercise. C.D. flights were analyzed along with the occurrence of SMS during flight and provocative testing before flight. Significant positive A90-13627# correlations were observed with serum chloride and significant ORTHOSTATIC INTOLERANCE POST SPACE FLIGHT - A negative correlations with serum phosphate, serum uric acid, and MULTIFACTORIAL DISORDER? plasma thyroid stimulating hormone. K.K. ANTONIO GUELL (CNES, Toulouse, France) IAF, International Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 5 p. refs A90-13631# (IAF PAPER 89-595) Copyright FLUID DISTRIBUTION PAlTERN INDUCED BY INTRAVENOUS The mechanisms involved in the physiopathogeny of the FLUID LOADING DURING HDT orthostatic intolerance observed after space flight are examined. F. BAISCH, G. BLOMQVIST, R. GERZER, M. HEER, A. The decrease in plasma volume from short-term and from long-term HILLEBRECHT (DLR, Cologne, Federal Republic of Germany) et weightlessness is addressed, and the causative factors are al. IAF, International Astronautical Congress, 40th, Malaga, Spain, discussed. The role of the low-pressure venous system in producing Oct. 7-13, 1989. 6 p. refs orthostatic intolerance is considered, emphasizing the role of the (IAF PAPER 89-599) Copyright limits of venous distension or the capability of veins to store more The hypothesis that prolonged HDT alters the systematic blood. Baroreception responsiveness is also briefly considered as responses to superimposed acute changes in the magnitude and a cause of orthostatic intolerance. C.D. distribution of intravascular volume is tested. The study group included six normal male subjects with a mean age of 26 + or - 4.4 yrs. Studies were carried out before, during, and after a 10 A90-13628'# National Aeronautics and Space Administration, day period of 6 deg head down tilt. HDT reduced plasma volume Washington, DC. by 16 percent, body weight by 2.4 percent, and cardiac output by EFFECTS OF BODY POSTURE ON THE INTERPRETATION OF 13 percent. K.K. BIOMEDICAL DATA OBTAINED FROM MANNED MISSIONS ARNAULD NICOGOSSIAN (NASA, Washington, DC), CAROLYN LEACH-HUNTOON, JOHN CHARLES, SAM POOL (NASA, Johnson A90-13632# Space Center, Houston, TX), and JOEL 1. LEONARD (Lockheed HORMONAL AND CARDIOVASCULAR CHANGES DURING Engineering and Sciences Co., Inc., Life Sciences Programs Off ice, LOWER BODY NEGATIVE AND POSITIVE PRESSURES Washington, DC) IAF, International Astronautical Congress, 40th, FLEMMING BONDE-PETERSEN (National Hospital, Copenhagen, Malaga, Spain, Oct. 7-13, 1989. 6 p. refs Denmark) IAF, InternationalAstronautical Congress, 40th, Malaga, (IAF PAPER 89-596) Spain, Oct. 7-13, 1989. 6 p. The role that different body postures may have on the (IAF PAPER 89-600) interpretation of inflight results is studied. The cardiovascular At least three different hormonal systems which actively measurements taken in the upright position more closely maintain and regulate arterial blood pressure are identified: the approximated the findings from space flight in the short-duration catecholamine system, the renin-angiotensin system, and the missions. However, the supine position most approximated the arginin-vasopressin system. Results from the literature and the long-duration missions. K.K. author's own experimental results show that the renin system plays a key role in the regulation of arterial pressure (and, eventually, in A90-13629# the etiology of arterial hypertension) especially during orthostatic HEMODYNAMICS DURING HEAD DOWN TILTING AND hypotension. However, arginin-vasopressin and the catecholamines LOWER BODY NEGATIVE PRESSURE AND are also called upon in near-syncope conditions. During this latter PHARMACOLOGICAL INTERVENTIONS FOR condition, a vasovagal reflex released from the heart muscle COUNTERMEASURES sensors dominates over the sympathetic drive leading to a H. LOELLGEN, K. KOPPENHAGEN, G. STRAUCH, and K. circulation collapse. In space conditions, the blood volume of man HARDIECK (Municipal Hospital, Remscheid; Berlin, Freie decreases and stays decreased for an extended period of time Universitaet, Federal Republic of Germany) IAF, International due to the regulatory mechanisms built into the physiological Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989 system. Because this situation cannot occur on earth, it is 3 P. concluded that the weightlessness condition offers a unique (IAF PAPER 89-597) Copyright opportunity to investigate the regulation of cardiovascular Pharmocological interventions assumed to counteract parameters. S.A.V. hemodynamic changes induced by head-down tilting (HDT) and lower body negative pressure (LBNP) are analyzed. Nitroglycerine was used for amelioration of HDT effects, dihydrergotamine for A90-13633# attenuation of LBNP effects. Changes during HDT and after EXPERIMENTAL RESEARCH ON THE APPLICABILITIES OF nitroglycerine were moderate and not significantly different from CHINESE MEDICINE TO SPACE MEDICINE control. In contrast, there were significant changes during LBNP RUIJUN ZHANG, JINKANG QIAN, ZHIZHEN SHI, JIANQUAN LAN, for hemodynamic parameters (decrease) and transcutaneously and BAOZHEN WANG (Institute of Space-Medico Engineering, analyzed blood gases. These alterations could be counterbalanced Beijing, People's Republic of China) IAF, International by dihydrergotamine in a significant way. The role of noninvasive Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 5 approach to simulated weightlessness and reentry is discussed. p. refs Author (IAF PAPER 69-601) Copyright Ground-based experimental results are presented on the A90-13630*# National Aeronautics and Space Administration. applicability of Chinese medicinal herbs as a countermeasure to Lyndon B. Johnson Space Center, Houston, TX. space flight deconditioning. The main principle behind Chinese BIOCHEMICAL CORRELATES OF NEUROSENSORY CHANGES medical treatment is to keep the opposite aspects of the body's IN WEIGHTLESSNESS functional states in equilibrium (the 'Yin-Yang' balance). The CAROLYN S. LEACH and MILLARD F. RESCHKE (NASA, Johnson Chinese medicinal herbs used are of natural origin and have minimal Space Center, Houston, TX) IAF, International Astronautical side effects. The herbs showed satisfactory results in protection Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 5 p. refs against gamma irradiation and seasickness in human subjects. (IAF PAPER 89-598) Copyright The herbs also alleviated headward blood stagnation in tilted rabbits The possible existence of a relationship between space motion and diminished bone loss in suspended rats. It is concluded that sickness and chemical and biochemical variables measured in body Chinese medicinal herb treatment shows promise in solving the fluids is studied. and endocrine measurements medical problems encountered in manned space flight. S.A.V.

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A90-13673'# Research Triangle Inst., Research Triangle Park, (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1043-1048. refs NC. (Contract N61339-86-D-0026; N61339-81-C-0105) NASA SPINOFFS TO BIOENGINEERING AND MEDICINE Copyright DORIS J. ROUSE, DANIEL L. WINFIELD, and S. CATHERINE Reports of posteffects following training sessions in Navy and CANADA (Research Triangle Institute, Research Triangle Park, Army flight simulators were obtained from pilots to determine the NC) IAF, International Astronautical Congress, 40th, Malaga, time course of recovery from simulator sickness. Results imply Spain, Oct. 7-13, 1989. 10 p. that posteffects may be a more serious problem than previously (Contract NASW-4367) considered; 45 percent of all those queried reported having (IAF PAPER 89-683) Copyright experienced symptoms of simulator sickness; 25 percent of the The societal and economic benefits derived from the application symptoms lasted more that 1 h after leaving the simulator; and 8 of aerospace technology to improved health care are examined, percent lasted more that 6 h. Postexposure symptoms were and examples of the space-technology spinoffs are presented. classified into the three categories: visuomotor, disorientation, and Special attention is given to the applications of aerospace nausea. A safety risk may be posed particularly by the moderately technology from digital image processing, space medicine and high frequency of symptoms involving postural disequilibrium. biology, microelectronics, optics and electrooptics, and ultrasonic Guidelines for coping with risks are discussed. Author imaging. The role of the NASA Technology Application Team in helping the potential technology users to identify and evaluate the A90-13736 technology transfer opportunities and to apply space technology PROPRANOLOLANDTHECOMPENSATORYCIRCULATORY in the field of medicine is discussed. IS. RESPONSES TO ORTHOSTASIS AT HIGH ALTITUDE CHARLES S. FULCO, ALLEN CYMERMAN, LAURIE A. TRAD (US. A90-13727# Army, Research Institute of Environmental Medicine, Natick, MA), YAW SENSORY REARRANGEMENT CHANGES PITCH JOHN T. REEVES (Colorado, University, Denver), PAUL 8. ROCK RESPONSES (US. Army, Fitzsimons Army Medical Center, Aurora, CO) et al. A. E. PETROPOULOS, C. WALL, 111 (Massachusetts Eye and Ear Aviation, Space, and Environmental Medicine (ISSN 0095-6562), Infirmary, Boston), and C. M. OMAN (MIT, Cambridge, MA) IAF, vol. 60, Nov. 1989, p. 1049-1055. refs International Astronautical Congress, 40th, Malaga, Spain, Oct. Copyright 7-13, 1989. 11 p. refs The possibility that tachycardia, mediated by beta-adrenergic (IAF PAPER ST-89-012) sympathetic stimulation, actually represents an essential response The hypothesis is tested as to whether sensory rearrangement involved in the maintenance of cardiac output during orthostasis (adaptation) of the magnitude of the canal-ocular response using at high altitude was investigated in human subjects who were combined visual vestibular stimuli during yaw rotation about an administered either 80 mg plopranolol or placebo at sea level and earth vertical axis will also be transferred to the otolith-ocular during the first 15 days of a 19-d altitude sojourn and were tilt-tested responses elicited by pitch rotation about an earth horizontal axis. at sea level and at high altitude. Heart rate, stroke volume, calf Previous studies demonstrated the nauseogenicity of the visual blood flow, and blood pressure were obtained during supine rest vestibular adaptation protocols, both in animals and in humans. and after 12 min of 60-deg tilt. In untreated subjects, no difference As a further step, the relationship observed by Wall and Smith was found between measurements at sea level and those at high (1989) between the degree of vestibulo-ocular reflex gain change altitude. Propranolol was found to cause reductions in heart rate and the severity of subjective discomfort experienced during the and blood pressure values in each of the tested position. It is adaptation protocols is investigated. S.A.V. concluded that tachycardia, both at rest and during upright tilt at high altitude, is important, but not essential to maintain cardiac A90- 13729# output. IS. SELECTIVE HYPERGRAVITY STIMULATION: ITS EFFECTS ON THE HUMAN BALANCE AND GAIT FUNCTIONS - A MODEL A90-13738 TO ASSESS, IN NORMAL GRAVITY CONDITIONS, SOME REDUCED SYSTOLIC BLOOD PRESSURE ELEVATIONS ASPECTS OF THE PERTURBATIONS INDUCED ON HUMAN DURING MAXIMUM EXERCISE AT SIMULATED ALTITUDES BODY BY MICROGRAVITY CONDITIONS J. KNUDTZON, K. MYHRE, W. RASCH, I. L. NESLEIN (Institute M. LAZERGES (loulouse 111, Universite, France) IAF, International of Aviation Medicine, Oslo, Norway), A. BOGSNES (Bergen, Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 9 Universitetet, Norway) et al. Aviation, Space, and Environmental p. Research supported by CNES and Matra, S. A. refs Medicine (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1072-1076. (IAF PAPER ST-89-016) Copyright refs The effects of the transition from hypergravity to normogravity Copyright on the reactions of muscle mechanoreceptors in humans were investigated. Hypergravity was selectively applied for 112 hr to A90-13739 the extensor muscles by means of two rubber extensible springs WORK CAPACITY, EXERCISE RESPONSES AND BODY stretched from shoulders to feet, inducing continuous hyperactivity COMPOSITION OF PROFESSIONAL PILOTS IN RELATION TO of the extensor muscles. The aftereffects of the selective AGE hypergravity stimulation (SHS) were assessed by means of dynamic J. A. LOEPPKY and U. C. LUFT (Lovelace Medical Foundation, balance examinations, using the Bessou et al. (1988) method, Albuquerque, NM) Aviation, Space, and Environmental Medicine and gait analyses, using the Bessou et al. (1989) method. It was (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1077-1084. refs found that, as a result of the SHS the efficiency of the dynamic Copyright balance function, measured 3 min after the hypergravity stimulus, The relationships between the work capacity of a pilot and his was improved in comparison with control. The efficiency of the age and body composition were investigated in 41 0 professional gait function was decreased immediately after the end of the SHS male pilots divided into age groups of 30, 39, 49, and 59 years application; this aftereffect disappeared 3 min later. IS. and subjected to a progressive upright bicycle ergometer test. It was found that, while the amount of fat tissue increased linearly A90-13735 with age, the fat-free weight was not significantly different between THE TIME COURSE OF POSTFLIGHT SIMULATOR SICKNESS groups. Aerobic work capacity fell at a rate of 0.25 ml/min per kg SYMPTOMS per year. A reversal of the age-related work-capacity decline was DENNIS R. BALTZLEY, ROBERT S. KENNEDY, KEVIN S. demonstrated for a subgroup or 10 pilots tested annually from BERBAUM (Essex Corp., Orlando, FL), MICHAEL G. LILIENTHAL age 31 to 47, which was attributed to regular physical exercising (US. Navy, Naval Training Systems Center, Orlando, FL), and and changes in personal health habits motivated by medical DANIEL W. GOWER (US. Army, Aeromedical Research Laboratory, prevention programs which incorporated self-assessment tests. Fort Rucker, AL) Aviation, Space, and Environmental Medicine IS.

40 52 AEROSPACE MEDICINE

AS13740 previously exposed to hyperbaric conditions (SCUBA). There are THE TIME REQUIRED FOR U.S. NAW FIGHTER PILOTS TO some underdocumented reports at lower altitudes. A suspected SHIFT GAZE AND IDENTIFY NEAR AND FAR TARGETS case of bends appearing at 14,000 ft (4,268 m) in a young student AILENE MORRIS and LEONARD A. TEMME (US. Navy, Naval Naval aviator is reported. The patient's only predisposing factors Aerospace Medical Research Laboratory, Pensacola, FL) Aviation, were an old athletic injury repaired with a permanently retained Space, and Environmental Medicine (ISSN 0095-6562), vol. 60, screw (foreign body) and a regular exercise program. A short Nov. 1989, p. 1085-1089. Research supported by the US. Navy. discussion of bends is included. Author Copyright The speed with which 163 US. Navy fighter pilots can shift A90-13745 their line of sight and discriminate high contrast acuity targets GALACTIC COSMIC RADIATION EXPOSURE AND was measured. The targets were simultaneously projected onto ASSOCIATED HEALTH RISKS FOR AIR CARRIER two screens; one at 18 ft and one at 18 inches in front of the CREWMEMBERS subject's eyes. Subjects were required to fixate first one screen W. FRIEDBERG, D. N. FAULKNER, L. SNYDER (FAA, Civil and then as rapidly as possible, shift gaze to the other screen. Aeromedical Institute, Oklahoma City, OK), E. B. DARDEN, JR. The minimum exposure duration required to correctly resolve both (Oak Ridge Associated Universities, TN), and K. O'BRIEN (Northern targets was measured. For 65 subjects, the test target was 1.0 Arizona University, Flagstaff, AZ) Aviation, Space, and min of visual angle (mva); for 98 subjects the target was 2.0 mva. Environmental Medicine (ISSN 0095-6562), vol. 60, Nov. 1989, p. The major findings are: (1) both Far-to-Near and Near-to-Far mean 1104-1108. refs times significantly slowed with ages; (2) there was no significant Copyright difference between the Far-to-Near and the Near-to-Far mean times The dose equivalent to air carrier crewmembers from Galactic with the oldest subject (44 years of age) excluded; (3) the cosmic radiation was estimated for each of 32 nonstop flights on within-subject standard deviation Far-to-Near increased with age a variety of routes to and from, or within, the contiguous United and was significantly greater than the Near-to-Far standard States. Flying times were from 0.4 to 13 hours. The annual dose deviation, which did not increase with age; and (4) there was a equivalents received on the flights ranged from 0.2 to 9.1 mSv significant correlation between the mean Near-to-Far speeds and (20 to 910 mrem), or 0.4 to 18 percent of the recommended the night carrier landing performance of the aviators. Author annual limit for occupational exposure of an adult. Some of the characteristics of Galactic and solar cosmic radiation are reviewed, A90-13741 and example calculations for estimating radiation-induced risks of RECOVERY TO +1GZ AND +2GZ FOLLOWING fatal cancer, genetic defects, and harm to an embryo or fetus are +GZ-INDUCED LOSS OF CONSCIOUSNESS - OPERATIONAL provided. The estimated increased risk of dying from cancer CONSIDERATIONS because of Galactic radiation exposure received during 20 years JAMES E. WHINNERY (US. Navy, Naval Air Development Center, of flying ranged from 0.1 to 5 in 1,000. For the adult US. population Warminster, PA), JOSEPH R. FISCHER (USAF, School of the risk of dying from cancer is about 220 to 1,000. Author Aerospace Medicine, Brooks AFB, TX), and NATHAN L. SHAPIRO (OAO Corp., San Antonio, TX) Aviation, Space, and Environmental A90-13746 Medicine (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1090-1095. OCCUPATIONAL INJURIES SUFFERED BY FLIGHT refs ATTENDANTS WHILE ON BOARD Copyright R. IGLESIAS, G. GONZALEZ, and S. T. MORALES (Mexicana The effect of potential in-flight recovery from +Gz-induced loss Airlines, Mexico City, Mexico) Aviation, Space, and Environmental of consciousness (G-LOC) on human physiology was investigated Medicine (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1109-111 1. in eight male subjects (not wearing anti-G suits and not performing Copyright anti-G straining maneuvers) exposed to +7 Gz with an onset rate lnflight occupational injuries suffered by flight attendants are of 6 G/sec until they became unconscious. Following the G-LOC, an important cause of medical disabilities. Mexicana Airlines has recovery to the usual +1 Gz level was compared to recovery to made an evaluation of this problem from 1983 to 1987. The injuries a +2 Gz level by comparing absolute, relative, and total most frequentJy observed were contusions, skin cuts, sprains, incapacitation times. The experiments demonstrated that no fractures, spine disorders, and severe barotitis. The anatomic measurable difference exists in the recovery from G-LOC, based regions commonly affected were the hands, feet, and spine. These on incapacitation times and tracking error when the Gz level is injuries are responsible for 15,573 work days lost for the average sustdined at +2 Gz post G-LOC. IS. of 1631 flight attendants. This study identified some unsafe actions and conditions in the flight attendants' working environment. The AS13742 company has initiated an extensive training program to avoid unsafe DEEP VENOUS THROMBOSIS IN THE MILITARY PILOT actions and to eliminate certain unsafe conditions where possible. RAYMOND P. STEINHAUSER and JOHN C. STEWART (USAF, Author Hospital Altus, Altus AFB, OK) Aviation, Space, and Environmental Medicine (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1096-1098. A90-14425 refs THE EFFECT OF OCCUPATIONAL WORK LOAD ON THE Copyright FUNCTIONAL STATE OF NAVAL-AVIATION FLIGHT Three cases of lower-extremity deep venous thrombosis (DVT) PERSONNEL [VLIIANIE PROFESSIONAL'NOI NAGRUZKI NA involving active duty US. Air Force pilots (at the Altus, Oklahoma, FUNKTSIONAL'NOE SOSTOIANIE LETNOGO SOSTAVA base) are examined together with the etiology, diagnosis, and KORABEL'NOI AVlATSll] treatment of DVT. One of these cases was caused by stasis, one S. G. MEL'NIK, A. V. SHAKUIA, and F. D. GLADKIKH by trauma, and one had no identified cause. The results of this Voenno-Meditsinskii Zhurnal (ISSN 0026-9050), July 1989, p. 54-57. investigation indicate that pilots with a history of deep venous In Russian. thrombosis may be returned to flying status. IS. Copyright Results are presented on several series of tests conducted on A90-13744 naval-helicopter pilots and navigators attached to long-term PROBABLE BENDS AT 14,000 FEET - A CASE REPORT missions to determine the relationship between flight-connected V. M. VOGE (US. Navy, Naval Hospital, Corpus Christi, TX) work loads and the functional state of their cardiovascular and Aviation, Space, and Environmental Medicine (ISSN 0095-6562), respiratory systems, as well as the resewe facilities of the organism. vol. 60, Nov. 1989, p. 1102, 1103. refs It was found that, at low latitudes, a 3-hr-long flight led to significant Copyright increases in the respiration frequency, a decrease in the breathing Decompression sickness has not previously been reported at resewe of the subjects, and increases in arterial pressure and altitudes below 16,000 ft (4.878 m), unless the patient had been heart rate. These shifts failed to normalize after 58 hrs of rest

41 52 AEROSPACE MEDICINE

(which was longer than the time allowed between two flight The effect of cervical position receptors on space orientation missions). At high latitudes, changes in these physiological is studied. The relationship between otoliths and cervical position parameters were more moderate and were found to return to receptors is examined. Measurements of reflectory eye rotations normal levels after only 16 hours of rest, indicating that the after various stimulations for the D1 mission astronauts and for long-lasting physiological shifts observed at low latitudes were 19 subjects on the ground are analyzed. Subjective vertical and caused by exposures to high temperatures during flight. IS. horizontal following stimulation are determined. The data reveal that stimulation of the neck receptors in weightlessness affects A90-15060 the perception of subjective vertical and horizontal and also has EXPERIMENT ON 'DISCOVERY' STS 514 - AGGREGATION a slight influence on ocular torsion. I.F. OF RED CELLS AND THROMBOCYTES IN HEART DISEASE, HYPERLIPIDAEMIA AND OTHER CONDITIONS A90-15477 L. DINTENFASS (Sydney, University; Rachel Forster Hospital, INTERNATIONAL UNION OF PHYSIOLOGICAL SCIENCES Redfern, Australia) (COSPAR, IAU, International Union of COMMISSION ON GRAVITATIONAL PHYSIOLOGY, ANNUAL Physiological Sciences, and International Academy of Astronautics, MEETING, lOTH, MONTREAL, CANADA, OCT. 9-14, 1988, Plenary Meeting and Workshops XVll and XVlll on Life Sciences PROCEEDINGS and Space Research XXlll(5) - Gravitational Biology, Espoo, ORR E. REYNOLDS, ED. (American Physiological Society, Finland, July 18-29, 1988) Advances in Space Research (ISSN Bethesda, MD) Physiologist, Supplement (ISSN 0031-9376), vol. 0273-1177), vol. 9, no. 11, 1989, p. 65-69. Research supported 32, Feb. 1989, 108 p. For individual items see A90-15478 to by Qantas Airways, Ltd., Rebecca Cooper Medical Research A90- 155 12. Foundation and CSIRO. refs Copyright Copyright This volume discusses topics on gravitational physiology and The aggregation of red cells in the blood of patients with its current concepts, recent space-flight results in gravitational ischaemic heart disease, diabetes, hyperlipidemia, and cancer, and physiology, and the effect of microgravity on the lung. Papers are in two normal donors has been investigated. Reconstituted blood presented on the NASA Ames Research Center's Life Sciences with IgC was also used. A 100-kg automated slit-capillary program, the possible mechanisms of changes in the kidney photoviscometer was set on the middeck of the Space Shuttle, response to ADH under hypogravity, and the effect of microgravity while an analogous instrument was at the Kennedy Space Center. on the reproductive function of male rats. Attention is also given Anticoagulated blood obtained from donors was adjusted to to the effect of a transition from the supine to upright positions haematocrit of 30 percent using native blood plasma. Blood was on the central hemodynamics in patients with a chest- forced to flow in the slit formed by two parallel glass plates during syndrome, calcium homeostasis in prolonged hypokinesia, and the experiment performed at 25 C. Intermittent macrophotography microgravity-induced changes in human bone strength. Other and microphotography of red cell aggregates formed during stasis papers are on immunocompetent cells producing humoral lasting 6 minutes were carried out. Results indicated that red cell mediators of bone-tissue mineral metabolism during a space-flight aggregates do form at zero g, that they are smaller than the ones simulation, temperature regulation in rats exposed to a 2-G field, obtained at 1 g, and that their morphology is different. C.E. central venous pressure in humans during short periods of weightlessness, and the significance of light and social cues in A90-15078 the maintenance of temporal organization in man. IS. INFLUENCE OF GRAVlTOlNERTlAL FORCE ON VESTIBULAR NYSTAGMUS IN MAN OBSERVED IN A CENTRIFUGE A90-15480 J. T. MARCUS, W. BLES (TNO, lnstituut voor Zintuigfysiologie, INTERSEROSAL PRESSURES AND CIRCULATORY Soesterberg, Netherlands), and C. R. VAN HOLTEN (Royal HOMEOSTASIS DURING CHANGES IN THE GRAVITATIONAL Netherlands Air Force, Aviation Medicine Div., Soesterberg, INERTIAL FORCE ENVIRONMENT Netherlands) (COSPAR, IAU, International Union of Physiological E. H. WOOD, J. BURSCH, and R. SEYFFER (Mayo Clinic, Sciences, and International Academy of Astronautics, Plenary Rochester, MN; Kiel, Universitaet, Federal Republic of Germany) Meeting and Workshops XVll and XVlll on Life Sciences and Space (International Union of Physiological Sciences Commission on Research XXlll(5) - Gravitational Biology, Espoo, Finland, July Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada, 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 9, no. 11, 1989, p. 213-222. refs 32, Feb. 1989, p. S-8 to S-11. Research supported by DARPA. Copyright refs The influence of gravity load on the vestibular system in man (Contract N66001-87-C-0079) was investigated in a centrifuge operating on the free swing Copyright principle. The vertical vestibular nystagmus induced by acceleration This paper discusses the hydrostatic basis for the retinal and to 3G was analyzed and compared with reference measurements cerebral ischemic anoxia and the resulting losses of vision and during 1G. The data indicate that the effects of increased gravity the cognitive function occurring during sustained exposures to G load include a prolonged decay time constant of upbeat nystagmus acceleration. Data are presented showing that the increase of and a subject-dependent persisting upbeat nystagmus. In an interserosal pressure gradients in response to the gravitational- attempt to explain these findings, an extension of the velocity inertial force environment provides homeostatic mechanisms for storage model is proposed, with gravity as a second stimulus effective protection of cardiovascular, respiratory, and cognitive function in addition to angular acceleration. Author functions under the increased-(; conditions. I.S.

A90-15079 A90-15481 INFLUENCE OF PROPRIOCEPTIVE INFORMATION ON SPACE RESPONSES TO CHANGED PERFUSION PRESSURE IN ORIENTATION ON THE GROUND AND IN ORBITAL WORKING MUSCLES - FACTORS TO BE CONSIDERED IN WEIGHTLESSNESS EXERCISE TESTING IN SPACE FLIGHTS? R. VON BAUMGARTEN, J. KASS, H. VOGEL, and J. WETZIG 0. EIKEN (Karolinska Institutet, Stockholm, Sweden) (International (Mainz, Universitaet, Federal Republic of Germany) (COSPAR, Union of Physiological Sciences Commission on Gravitational IAU, InternationalUnion of Physiological Sciences, and International Physiology, Annual Meeting, 1Oth, Montreal, Canada, Oct. 9-14, Academy of Astronautics, Plenary Meeting and Workshops XVll 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. and XVlll on Life Sciences and Space Research XXlll(5) - 1989, p. S-12 to S-15. refs Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances Copyright in Space Research (ISSN 0273-1177), vol. 9, no. 11, 1989, p. The effect of graded changes in the muscle-perfusion ysssure 223-230. refs on physiologic1 responses of man to dynamic leg exercises was Copyright investigated. The muscle-perfusion pressure was reduced by

42 52 AEROSPACE MEDICINE

exposing working legs of human subjects (whose feet were after 370 days of bed rest are analyzed. In the first test group strapped to the pedals of a cycle ergometer) to a supraatmospheric after 120 days of bed rest a decrease in rigidity and in deformation pressure of 50 mm Hg (leg positive pressure, LPP); the pressure energy of 61.0 percent and 41.0 percent, respectively is noted. was increased by exposing the legs to a subatmospheric pressure The use of countermeasures by this test group after 120 days of of -50 mm Hg (lower body negative pressure, LBNP). Results bed rest reveals a partial recovery of bone mechanical strength. show that exercise-induced increases in the 02 uptake and blood The second test group, which employed countermeasures from lactate concentration were both attenuated by LBNP and day one, show a decrease in bone strength of 6.0 percent, an exaggerated by LPP. The changes in the blood lactate levels are increase in rigidity of 12.0 percent, and deformation and energy attributed to the perfusion-pressure-dependent variation in the of failure decreases of 24.0 and 12.0 percent, respectively. It is muscle blood flow, resulting in opposite changes in the share concluded that countermeasures may help to maintain spongy bone contributed by anaerobic metabolism to the energy release. I.S. strength in simulated microgravity. I.F.

A90-15490 A90-15495 McGill Univ., Montreal (Quebec). EFFECTS OF TRANSITION FROM SUPINE TO UPRIGHT OTOLITH-SPINAL REFLEX TESTING ON SPACELAB-1 AND POSITIONS ON CENTRAL HEMODYNAMICS IN PATIENTS D-1 WITH CHEST PAIN SYNDROME D. G. D. WATT, L. M. TOMI, H. BETTER (McGill University, BERNARD J. RUBAL, DAVID S. GANTT, JULIO J. BIRD, and Montreal, Canada), and K. E. MONEY (DND, Defence and Civil TED A. WILKENS (U.S. Army, Brooke Army Medical Center, Fort Institute of Environmental Medicine, Downsview, Canada) Sam Houston, TX) (International Union of Physiological Sciences (International Union of Physiological Sciences Commission on Commission on Gravitational Physiology, Annual Meeting, 1Oth, Gravitational Physiology, Annual Meeting, loth, Montreal, Canada, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 0031-9376), vol. 32, Feb. 1989, p. S-33, S-34. 32, Feb. 1989, p. S-49 to S-52. Research supported by the Medical Copyright Research Council of Canada, DND, and NASA. refs The effect of a posture change from the supine to the upright Copyright positlions on central hemodynamic of humans was investigated in The responses of otolith organs to drop testing on land and in nine male patients with chest pain syndrome (with four of the flight are studied using electromyographic (EMG) activity. It is patients showing evidence of significant coronary artery disease). observed that EMG response consists of two subcomponents. Simultaneous right atrial, right ventricular, and pulmonary artery The two subcomponents can vary independently during prolonged pressures and/or left ventricular and aortic pressures were obtained exposure and the first subcomponent is not susceptible to voluntary using catheter-mountedmultisensor micromanometers. Results are control and the second subcomponent can be affected by mental presented, demonstrating that an active transition from the supine set. The mean amplitudes of the first subcomponent of the EMG to the upright position produces complex changes in the left and response to sudden falls in four Spacelab-1 crew members and right heart pressures which may be attributed not only to hydrostatic five Spacelab D-1 crew members are analyzed during pre-, in-, changes but also to the transient effects of isometric and Valsalva and post-flight testing. It is observed that otolith-spinal reflex strains. The morphology of the pressure waveforms exhibited function varies during prolonged exposure to microgravity and the significant differences between the supine and the upright subject’s preflight motor strategy affects the degree of variation. positions. I.S. I.F.

A90-15492 A90-15496 CALCIUM HOMEOSTASIS IN PROLONGED HYPOKINESIA IMMUNOCOMPETENT CELLS PRODUCING HUMORAL B. V. MORUKOV, 0. 1. ORLOV, and A. 1. GRIGOR’EV (Institut MEDIATORS OF BONE TISSUE MINERAL METABOLISM Mediko-Biologicheskikh Problem, Moscow, USSR) (International DURING SPACE FLIGHT SIMULATION Union of Physiological Sciences Commission on Gravitational A. T. LESNIAK, I. V. KONSTANTINOVA, N. V. BODZHIKOV, and Physiology, Annual Meeting, 1Oth, Montreal, Canada, Oct. 9-14, P. N. UCHAKIN (Institut Mediko-Biologicheskikh Problem, Moscow, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. USSR) (International Union of Physiological Sciences Commission 1989, p. S-37 to S-40. refs on Gravitational Physiology, Annual Meeting, loth, Montreal, Copyright Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN The effects of prolonged (120- and 182-day) head-down tilt on 0031-9376), vol. 32, Feb. 1989, p. S-53 to S-56. refs the calcium metabolism, its hormonal regulation, and renal Copyright calciuretic function of humans were investigated in 20 healthy The dynamics of production of humoral mediators activating subjects. It was found that the 182-day head-down tilt caused resorption are studied. Sixty-one healthy males participated in the gradual increases in the blood contents of total and ionized calcium test; 15 were exposed to head down tilt (HDT) for 120 days, 10 and parathyroid hormone, while the concentration of calcitonin subjects for 370 day, and 36 males performed routine daily increased only at an early stage of tilt and decreased thereafter. activities. Data from fifteen patients with local osteoporosis are This resulted in a negative calcium balance, which was on the also examined. Supernatant resorbing activity in the leucocytes average 5.6 g per month. Measurements in biopsy samples from cultures of these subjects are analyzed. It is noted that the ability the iliac bone showed a calcium decrease and phosphorus of mononuclears to produce mediators activating resorption increase. I.S. increases with the duration of bed rest. I.F.

A90-15493 A90-15501 National Aeronautics and Space Administration. John MICROGRAVITY-INDUCED CHANGES IN HUMAN BONE F. Kennedy Space Center, Cocoa Beach, FL. STRENGTH CHANGES OF MUSCLE FUNCTION AND SIZE WITH BEDREST G. P. STUPAKOV, V. S. KAZEIKIN, and B. V. MORUKOV (Institut GARY A. DUDLEY (NASA, Kennedy Space Center; Bionetics Cop., Mediko-Biologicheskikh Problem, Moscow, USSR) (International Cocoa Beach, FL), PHILIP D. GOLLNICK (Washington State Union of Physiological Sciences Commission on Gravitational University, Pullman), VICTOR A. CONVERTINO, and PAUL Physiology, Annual Meeting, loth, Montreal, Canada, Oct. 9-14, BUCHANAN (NASA, Kennedy Space Center, Cocoa Beach, FL) 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. (International Union of Physiological Sciences Commission on 1989, p. S-41 to S-44. refs Gravitational Physiology, Annual Meeting, loth, Montreal, Canada, Copyright Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. Variations in the spongy tissue strength of bones due to 32, Feb. 1989, p. S-65, S-66. refs microgravity and countermeasures to prevent bone strength Copyright changes are studied. The mechanical properties of iliac bone The impact of a short-term head-down bedrest on the samples from nine healthy males ranging from 27 to 42 years skeletal-muscle function of humans was investigated in healthy

43 52 AEROSPACE MEDICINE males subjected (after five days of control period) to 30-day 6-deg Sciences Commission on Gravitational Physiology, Annual Meeting, head-down bed rest (BR) followed by a five-day recovery period. 1Oth, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement It was found that the head-down BR led to a decrease in force (ISSN 0031-9376), vol. 32, Feb. 1989, p. S-73 to S-76. Sponsorship: developed by the knee extensor muscle group during maximal Danish Space Board. refs voluntary efforts, with the average reduction of 21 percent across (Contract DSB-1112-33185) the speeds of concentric and eccentric muscle action. Significant Copyright decreases were also found in the cross-sectional areas of The effect of short-period exposures to weightlessness slow-twitch and fast-twitch muscle fibers of the vastus lateralis. (parabolic maneuvers) on central venous pressure (CVP) was I.S. investigated in human subjects fitted with catheters inserted through a cubital vein. It was found that an acute onset of weightlessness A90-15502" National Aeronautics and Space Administration. John in upright seated humans during parabolic flights led to significant F. Kennedy Space Center, Cocoa Beach, FL. increases in CVP, compared with both the supine and upright CAROTID BAROREFLEX RESPONSE FOLLOWING 30 DAYS sitting positions at 1 G before the maneuver. These results indicate EXPOSURE TO SIMULATED MICROGRAVITY that CVP may elevate during the initial period of weightlessness V. A. CONVERTINO, D. F. DOERR, D. L. ECKBERG, J. M. in orbital flights. I.S. FRITSCH, and J. VERNIKOS-DANELLIS (NASA, Kennedy Space Center, Cocoa Beach, FL; NASA, Ames Research Center, Moffett A90-15505 Field, CA; Virginia, Medical College, Richmond) (International CARDIORESPIRATORY RESPONSES TO SIMULATED Union of Physiological Sciences Commission on Gravitational WEIGHTLESSNESS IN MAN Physiology, Annual Meeting, 1Oth, Montreal, Canada, Oct. 9-14, V. P. KATUNTSEV, V. E. KATKOV, V. M. BARANOV, and A. M. 1988) Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. GENIN (Institut Mediko-Biologicheskikh Problem, Moscow, USSR) 1989, p. S-67, S-68. (International Union of Physiological Sciences Commission on Copyright Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada, The mechanism of the carotid-baroreflex response to Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. weightlessness was investigated in human subjects exposed to 32, Feb. 1989, p. S-77 to S-81. refs simulated microgravily (30 days of 6-day head-down bed rest Copyright followed by 5 days of recovery). Baroreceptor-cardiac reflex The effects of 7-day simulated weightlessness ('dry immersion' responses were elicited by a complex sequence of pressure as described by Shulzhenko and Vil-Vilyams, 1976) on the changes delivered to a neck chamber device. The shape of the cardiorespiratory parameters and the concentrations of gases and sigmoid baroreceptor-cardiac response curve was examined for oxygen saturation of arterial blood were investigated in healthy alterations and the occurrence of resetting, as well as for a possible human subjects. Results showed that, during the first 7 hrs of association of the impaired baroreflex function with hypotension immersion, the major parameters of central circulation were during the postexposure orthostatic stress. It was found that the consistently high. On day 2, the values for the central venous exposure to head-down bed rest caused a significant shift on the pressure, mean pulmonary pressure, heart rate, and cardiac indices R-R interval axis, which paralleled reductions and elevations in decreased by 64.1, 37.3, 13.9, and 15.9 percent, respectively. baseline HR such that the baseline R-R (operational point) These cardiorespiratory responses seem to be typical of the early remained in the same position on the response curve. This shift stages of adaptation to fluid shifts in the cranial direction which in the location of the reflex relation indicates a significant resetting occur in space flights. IS. of the carotid baroreceptors, which may represent an appropriate adaptation which contributes to the maintenance of a constant A90-15506 resting arterial blood pressure before, during, and after bed rest, GRAVITATIONAL INFLUENCE ON SYSTEMIC ARTERIAL observed in these study. IS. DYNAMICS USING A 3-ELEMENT WINDKESSEL MODEL RlCKY D. LATHAM, BERNARD J. RUBAL, and ROBERT S. A90-15503 SCHWARTZ (US. Army, Brooke Army Medical Center, Fort Sam PLASMA ANF CONCENTRATIONS DURING HEAD-DOWN BED Houston, TX) (International Union of Physiological Sciences REST OF VARIOUS DURATION (FROM SEVERAL HOURS TO Commission on Gravitational Physiology, Annual Meeting, 1Oth, ONE MONTH) - ROLE OF LBNP COUNTERMEASURE Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN C. GHARIB, G. GAUQUELIN, G. GEELEN (Lyon I, Universite, 0031-9376), vol. 32, Feb. 1989, p. S-82, S-83. France), PH. ARBEILLE, F. PAPAT (Tours, Universite, France) et Copyright al. (International Union of Physiological Sciences Commission The effects of 70-deg upright tilt on the systemic compliance on Gravitational Physiology, Annual Meeting, 1Oth, Montreal, (C), characteristic aortic input impedance (Zc), and peripheral Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN resistance (R) is investigated experimentally in six sedated baboons 0031-9376), vol. 32, Feb. 1989, p. S-69 to S-72. Research equipped with catheter micromanometers and flowmeters. Details supported by CNES and Foundation pour la Recherche Medicale. of the data acquisition and analysis (using a three-element refs Windkessel computer model) are discussed, and the results are (Contract DRET-87-056) presented in tables and graphs. Passive upright tilt is found to Copyright affect Zc and R more significantly than C; the computer model The effects of short-term and long-term head-down bed rest provided a good fit to the experimental data. T.K. (HDBR) on the blood content of atrial natriuretic factor (ANF) were investigated, along with the effect on the ANF secretion of A90-15507 LBNB, used as a countermeasure to prevent orthostatic intolerance. REGIONAL AORTIC PRESSURE APPARENT PHASE Results showed that the secretion of ANF into blood had a trend VELOCITY IN THE BABOON DURING 70 DEGREE TILT to decrease in response to the HDBR, probably in response to BARCIAY P. BUTLER, BERNARD J. RUBAL, RlCKY D. LATHAM, sodium loss; the use of LBNP led to an initial increase of the and ROBERT S. SCHWARTZ (US Army, Brooke Army Medical ANF secretion, followed by a gradual decrease. IS. Center, Fort Sam Houston, TX) (International Union of Physiological Sciences Commission on Gravitational Physiology, A90-15504 Annual Meeting, loth, Montreal, Canada, Oct. 9-14, 1988) CENTRAL VENOUS PRESSURE IN HUMANS DURING SHORT Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. 1989, PERIODS OF WEIGHTLESSNESS p. S-84, S-85. PETER NORSK, NIELS FOLDAGER, FLEMMING Copyright BONDE-PETERSEN, BENNY ELMANN-IARSEN, and STAEHR The effects of 70-deg upright tilt on the regional vascular TORBEN JOHANSEN (Rigshospitalet, Copenhagen; Royal Danish properties of the aorta are investigated experimentally in Air Force, Vaerlose, Denmark) (International Union of Physiological eight lightly anesthetized mature baboons equipped with

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micromanometer catheters. Apparent phase velocity (APV) is The measurement techniques and experimental protocols are determined by taking discrete Fourier transforms of pressure pulses outlined, and selected results are presented in graphs. In HUT, measured simultaneously by separate micromanometers. The data WI after 50 min of exercise is significantly greater at 35 C than at are presented in tables and graphs and briefly characterized. No 25 C; in HDT, on the other hand, there is no significant difference significant difference is found between supine and upright regional in WI at the two temperatures. WI is significantly correlated with APV, although the most distal APV in the upright position is stroke volume, indicating that an increase in central blood volume significantly greater than the proximal APV (p less than 0.05). may inhibit WI. T.K. T.K. A90-15511 ~90-1550a PILOT PERFORMANCE IS INCREASED AFTER ALTERNATING HEMODYNAMICS OF LEG VEINS DURING A 30 DAYS BED HYPO- AND HYPERGRAVITY STATES REST - EFFECT OF LOWER BODY NEGATIVE PRESSURE J. SYKORA, I. SOLCOVA, 0. PELCAK, and J. DVORAK (LBNP) (Ceskoslovenska Akademie Ved, Fyziologicky Ustav, Prague, FRANCIS LOUlSY and C. Y. GUEZENNEC (Centre &Etudes et Czechoslovakia) (International Union of Physiological Sciences de Recherches en Medecine Aerospatiale, Paris, France) Commission on Gravitational Physiology, Annual Meeting, 1Oth, (International Union of Physiological Sciences Commission on Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement (ISSN Gravitational Physiology, Annual Meeting, 1Oth, Montreal, Canada, 0031-9376), vol. 32, Feb. 1989, p. S-92, S-93. Oct. 9-14, 1988) Physiologist, Supplement (ISSN 0031-9376), vol. Copyright 32, Feb. 1989, p. S-86, S-87. The effects of repeated short exposures to weightlessness (in Copyright a transport aircraft performing Keplerian trajectories) on the The effects of LBNP on the cardiovascular response to 30-day performance of experienced pilots in aerobatic test maneuvers bed rest with -6-deg head-down tilt are investigated experimentally are investigated experimentally. Pilots perform the test maneuvers in six subjects. LBNP is administered to three subjects for 3 x 20 before and after either a rest period (controls) or exposure to min during weeks 1-3, 4 x 20 min during days 1-4 of the fourth alternating weightlessness and hypergravity (experimental group); week, and 6 x 20 min during the last days of bed rest. Leg performance data are presented in tables and briefly characterized. venous compliance measurements are obtained by strain-gage Performance on the second trial is found to be better than on the plethysmography before, during and after the bed-rest period; the first in both the experimental and control groups; Le., exposure to results are presented in graphs and briefly discussed. The this type of weightlessness has no measurable adverse effects. usefulness of -6-deg head-down bed rest as a model for simulating T.K. exposure to microgravity and the efficacy of LBNP in counteracting the adverse effects of microgravity on capacitance vessels are demonstrated. T.K. A90-15512’ National Aeronautics and Space Administration. Ames Research Center, Moffett Field, CA. A90-15509 SIGNIFICANCE OF LIGHT AND SOCIAL CUES IN THE DIFFERENCE IN CARDIOVASCULAR RESPONSES TO BLOOD MAINTENANCE OF TEMPORAL ORGANIZATION IN MAN POOLING PATTERNS BETWEEN LBNP AND HEAD UP C. M. WINGET, C. W. DEROSHIA (NASA, Ames Research Center, TILTING STIMULATED AFTER SUPINE CYCLING IN WOMEN Moffett Field, CA), K. H. OGAWA, and D. C. HOLLEY (San Jose S. TORIKOSHI, K. YOKOZAWA (Tokyo Women’s Christian State University, CA) (International Union of Physiological University, Japan), J. NAGANO (Bunka Women’s University, Japan), Sciences Commission on Gravitational Physiology, Annual Meeting, and Y. SUZUKI (Tokyo, University, Japan) (International Union 1Oth, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement of Physiological Sciences Commission on Gravitational Physiology, (ISSN 0031-Q376), vol. 32, Feb. 1989, p. S-94, S-95. refs Annual Meeting, loth, Montreal, Canada, Oct. 9-14, 1988) Copyright Physiologist, Supplement (ISSN 0031-9376), vol. 32, Feb. 1989, The effects of 1ight:darkness (LD) cycles and social interaction p. s-88, s-89. on the response to long-term confinement (105 days) were Copyright investigated experimentally in three groups of three male subjects The effects of 40-deg head-up tilt (HUT) or LBNP on aged 20-24 years. Data from measurements of physiological cardiovascular response after 20 min of mild supine cycle exercise parameters indicating changes in circadian rhythms are presented are investigated experimentally in five female subjects. V02, heart in graphs and analyzed; it is found that the LD-induced rhythm rate, arterial blood pressure, cardiac output, forearm blood flow, changes observed in previous studies of subjects isolated singly and leg volume are measured before, during, and after exercise, do not appear when subjects are confined in groups of three, and the results are presented in graphs. It is found that the increase suggesting a positive adaptive effect of social contact. In one in leg volume (Delta LV) induced by HUT is greater than that subject who was transferred to a different group at day 84, hostile induced by LBNP, and that Delta LV is significantly correlated to social interactions and poor circadian-rhythm entrainment were stroke volume, cardiac output, and total peripheral resistance. It observed; the possible reasons for this response are considered. is inferred that decreased venous return triggers the sympathetic T.K. to maintain arterial pressure. T.K. A90-16299 A90-15510 LIFE BEYOND GRAVITY INCREASING CENTRAL BLOOD VOLUME WITH HEAD-DOWN JAN ZIEGLER Air and Space (ISSN 0886-2257), vol. 4, Dec. TILTING WOULD INHIBIT WATER INTAKE DURING MILD 1989-Jan. 1990, p. 81-87. PEDALING AT 25 C AND 35 C ROOM TEMPERATURES IN Copyright WOMAN In anticipation of prospective Mars manned mission crews’ need KIKUKO YOKOZAWA, SHIGEYO TORIKOSHI, JUNK0 NAGANO to maintain their physical health during several months of (Tokyo Women’s Christian University, Japan), and YOJl SUZUKI weightlessness, aerospace physicians have become concerned (Tokyo, University, Japan) (International Union of Physiological with the effect of microgravity conditions on bone and muscle Sciences Commission on Gravitational Physiology, Annual Meeting, tissues. Bones tend to become thinner and more porous; muscles loth, Montreal, Canada, Oct. 9-14, 1988) Physiologist, Supplement slacken and atrophy to the point where full recovery of strength (ISSN 0031-9376), vol. 32, Feb. 1989, p. S-90, S-91. may take several months of postmission conditioning on earth. Copyright The first phase of a NASA research program will investigate the The effects of ambient temperature (25 or 35 C) on water ability of crewmembers’ inner ears to tolerate rotation in intake (Wl) and cardiovascular parameters during 1 h of microgravity. A second phase will attempt to determine whether 300-kpm/min exercise in 1Odeg head-up or head-down tilt (HUT artificial gravity must be applied continuously or will suffice when or HDT) are investigated experimentally in five female subjects. used intermittently. O.C.

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A90-16535 A90-16625" National Aeronautics and Space Administration, EXERCISE STRATEGIES AND ASSESSMENT OF Washington, DC. CARDIORESPIRATORY FITNESS IN SPACE SPACE PHYSIOLOGY AND MEDICINE (2ND EDITION) GEORGE D. SWANSON (Colorado, University, Denver) IN: The ARNAULD E. NICOGOSSIAN, ED. (NASA, Washington, DC), case for Mars 111: Strategies for exploration - Technical. San Diego, CAROLYN LEACH HUNTOON, ED., and SAM L. POOL, ED. (NASA, CA, Univelt, Inc., 1989, p. 141-149. Research supported by the Johnson Space Center, Houston, TX) Philadelphia, PA, Lea and University of Colorado. refs Febiger, 1989, 414 p. No individual items are abstracted in this (AAS PAPER 87-236) Copyright volume. Assessing cardiorespiratory fitness in space will involve the Copyright use of specific exercise strategies as test work rate inputs. The The fundamental biomedical issues involved in manned space purpose of this paper is to consider exercise test strategies and flght are examined in review chapters contributed by leading U.S. breath-by-breath gas exchange concepts for utilizing oxygen experts. Sections are devoted to the history of manned space consumption time series in the assessment of cardiorespiratory flight, the space environment, space-flight systems and procedures, fitness. A modeling approach is emphasized. Author physiological adaptation to space flight, health maintenance of space crewmembers, and medical problems of space flight. Extensive diagrams, drawings, graphs, photographs, and tables of A90-16536 numerical data are provided. T.K. WORK ON HUMAN ADAPTATION TO LONG-TERM SPACE FLIGHT IN THE UK N90-12160# New York Univ., New York. Dept. of Psychology. P. A. HANSSON (Commercial Space Technologies, Ltd., London; VISUAL MOTION PERCEPTION Interim Report, 1 Feb. 1988 - Institute for Space Biomedicine, Sheffield, England) IN: The case 31 Jan. 1989 for Mars 111: Strategies for exploration - Technical. San Diego, CA, GEORGE SPERLING 31 Jan. 1989 7 p Univelt, Inc., 1989, p. 151-160. refs (Contract AF-AFOSR-0140-88; AF PROJ. 231 3) (AAS PAPER 87-237) Copyright (AD-A210994; AFOSR-89-1021TR) Avail: NTlS HC A02/MF A01 Several studies on human adaptation to long-term space flight CSCL 06/4 have been performed in the UK. All these studies aimed at servicing Two separate motion-computation systems and the derivation of polar platforms, space industrialization in polar orbit or GEO, of the functional properties of each were explored. A dynamic interplanetary manned flights to Mars and beyond, and testing for stimulus was demonstrated that caused the first- and second-order man presence in GEO. The basic lines of investigation included: motion perception systems to perceive motion in opposite a biomedical research program using animals; a human health directions, depending on viewing distance. Motion/texture maintenance program based on experience in health care in the interactions-stimuli were discovered that are accessible only to offshore oil industry, in Antartica etc.; and a biophysics program second order motion analysis and then only after their texture based on free radical and HZE particle studies. C.E. has first been extracted. It was also demonstrated that perceiving 3D structure from 2D visual inputs depends primarily on the first-order motion perception system. A new spatial interaction was A90-16537 also found in which a textured area surrounded by a similar ASTRONAUT INTERDISCIPLINARY AND MEDICAL/DENTAL high-contrast texture appears to be of lower contrast when TRAINING FOR MANNED MARS MISSIONS surrounded by neutral gray. This remarkable phenomenon HAROLD E. FILBERT (Martin Marietta Corp., Denver, CO) and DONALD J. KLEIER (Colorado, University, Denver) IN: The case contradicts all current theories of lightness perception. GRA for Mars 111: Strategies for exploration - Technical. San Diego, CA, Univelt, Inc., 1989, p. 161-170. N90-12161# Naval Health Research Center, San Diego, CA. (AAS PAPER 87-238) Copyright Applied Physiology Dept. This paper presents a general discussion of the medical and DEMONSTRATION OF REPLICABLE DIMENSIONS OF HEALTH dental needs of astronauts on a manned Mars mission and a BEHAVIORS Interim Report study of tradeoffs in meeting those needs. The discussion is based ROSS R. VICKERS, JR., TERRY L. CONWAY, and LINDA K. on the concept of interdisciplinary astronaut training/skills for HERVIG 6 Oct. 1988 24 p prolonged manned space missions. The authors focus on the (AD-A211920; NHRC-88-41) Avail: NTlS HC AO3/MF A01 advantages of at least two years of intensive training in general CSCL 06/5 medical practice and dentistry, with emphasis on space medicine Appropriate health behaviors are necessary to ensure health and remote practice skills for all astronauts assigned to the mission. and well-being, thereby keeping military personnel ready to perform Existing, federally-funded training programs and facilities to their jobs which may demand exceptional efforts at key times. An accomplish the task are cited. Author understanding of factors influencing health behaviors would be more readily achieved if general dimensions could be identified to delineate sets of health behaviors that consistently co-occur. Prior A90-16538 research has suffered from the use of only brief lists of health AUTOMATION OF FITNESS MANAGEMENT FOR EXTENDED behaviors, failure to systematically select health behaviors to SPACE MISSIONS represent hypothesized health behavior dimensions, and failure to TED D. WADE, PHILIP G. SMALDONE, and RICHARD G. MAY replicate findings across samples. The present study was designed (Colorado, University, Denver) IN: The case for Mars 111: Strategies to extend prior efforts by determining the number of dimensions for exploration - Technical. San Diego, CA, Univelt, Inc., 1989, p. of health behavior that could be reliably identified in two samples 171-188. Research supported by the University of Colorado. of Navy personnel. A set of 40 health behavior items was chosen refs to represent four major dimensions of health behavior that prior (AAS PAPER 87-239) Copyright work suggested were present in groups representing a wide range A design and rationale are proposed for a system to automate of social and demographic backgrounds. GRA the management of counter-measures to effects of space on human fitness, incorporating modeling and feedback of goals and N90-12162# Illinois Inst. of Tech., Chicago. performance to refine a person's program of counter measures. COMPUTER GENERATION OF A TUTORIAL DIALOGUE Although essential biomedical knowledge is not yet available, the Quarterly Progress Report, 1 Jun. - 31 Aug. 1989 system could help generate that knowledge, and several problems MARTHA EVENS, JOEL MICHAEL, and ALLEN ROVICK 31 in its development do not require the knowledge. As it developed, Aug. 1989 7 p the system would be useful on earth and in space at steps along (Contract N00014-89-J-1952) the way to a Mars mission. On interplanetary journeys, a nearly (AD-A211976) Avail: NTlS HC A02/MF A01 CSCL 1215 autonomous system could be essential. Author The main focus was on the taping of human-to-human tutoring

46 52 AEROSPACE MEDICINE sessions and the analysis of the transcripts of those sessions illness treatment. This article will attempt to integrate and extend with regard to both language and content. The language analysis some of those ideas. GRA involves study of vocabulary, syntax, semantics, and discourse for use in the understanding of ill-formed input and the generation of N90-12165# Army Research Inst. of Environmental Medicine, responses. The analysis of content focuses on tutoring rules, Natick, MA. modeling rules, and the underlying knowledge used by the tutor. HUMAN BODY REGIONAL CONVECTIVE HEAT TRANSFER The development of the lexical functional grammar rules and DETERMINATION USING SUBLIMATING NAPHTHALENE lexicon for the cardiovascular sublanguage, the development of a DISKS cardiovascular knowledge base for the tutoring system, a Prolog STEPHEN KW. CHANG and RICHARD R. GONZALEZ Jul. prototype for the tutor being built, and the initial plans for a tutoring 1989 22 p system in Lisp to support the research in text generation are all (Contract DA PROJ. 3E1-62787-A8-78) being examined in detail. The context of the work is an attempt (AD-A212170; ARIEM-M66-89) Avail: NTlS HC A03/MF A01 to build an intelligent version of a remarkably effective conventional CSCL 0614 tutoring program, CIRCSIM, designed and implemented in Basic. The regional convective heat transfer coefficients(hc) on the CIRCSIM is intended to tutor first year medical students in the human body were determined using sublimating naphthalene disks. complex negative feedback processes used by the human body Circular naphthalene disks were affixed to various body segments to maintain blood pressure. GRA of a stationary, life size manikin, under constant temperature and wind speed in an environmental chamber. The amount of naphthalene weight loss through sublimation was translated to hc N90-12163# Army Research Inst. of Environmental Medicine, using the Chilton-Colborn j-factor analogy between heat and mass Natick, MA. transfer. The regional convective heat transfer coefficients can be THE EFFECT OF CAFFEINE ON ENDURANCE TIME TO determined by using strictly the heat-mass transfer analogy, EXHAUSTION AT HIGH ALTITUDE excluding any supplementary technique of cylindrical body segment CHARLES S. FULCO, PAUL B. ROCK, LAURIE A. TRAD, approximations or other shape extrapolations. The logarithmic mean MADELINE S. ROSE, VINCENT A. FORTE, JR., PATRICIA M. density factor for naphthalene sublimating in air (PAM,n) was also YOUNG, and ALLEN CYMERMAN 27 Apr. 1989 43 p determined. PAM,n for the naphthalene-air sublimation environment (AD-A212069) Avail: NTlS HC A03/MF A01 CSCL 06/15 is only one third of the water vapor-air diffusion environment (PAM). Endurance time to exhaustion (ETX) is increased at high altitude PAM,n is an essential factor for extracting the correct hc value (HA) but only after 2 weeks of continued exposure. The increase from the naphthalene mass transfer data. GRA is thought to be related to a delayed depletion of muscle glycogen, secondary to HA-induced increases in the mobilization and N90-12166# California Univ., Irvine. Center for the Neurobiology utilization of free fatty acids (FFA). It was determined if caffeine (CAF), which stimulates FFA mobilization, could prolong ETX earlier of Learning and Memory. in the HA exposure. Eight untrained men (17 to 24 yr) performed ADAPTIVE INFORMATION PROCESSING IN AUDITORY CORTEX Annual Report, 1 Jun. 1988 31 May 1989 2 ETX cycling bouts at 79 to 85 percent of their altitude-specific - maximal oxygen consumption in each of 3 phases: at sea level NORMAN M. WEINBERGER 31 May 1989 51 p (Contract NO0014-87-K-0433) (SL), after 1 h simulated exposure (acute), and after 2 weeks (chronic) at 4300 m. Subjects received either a CAF (4 mg/kg) or (AD-A211294) Avail: NTlS HC A04/MF A01 CSCL 0614 a placebo drink in a double-bind cross-over design 1 h prior to The principles of biological intelligence are of central importance to the understanding of brain function and to the each ETX bout in each phase. Subjective ratings of perceived development of devices based on the extraordinary computing exertion (PE) and cardiac output (CO) were obtained during exercise. Daily caloric intake and composition were held constant. and information processing abilities of brains. Adaptive cognitive CAF did not alter ETX at SL but was increased by 54 percent and behavioral performance must be based on principles of brain function that have been selected in evolution so that organisms (22.0 to 35.0 min, p=.04) and 24 percent (30.8 to 38.5 min, p=O.1 1) during acute and chronic HA exposure, respectively. The can successfully cope with environmentaldemands. Although these improvements in ETX were determined not to be associated with principles are not yet known, they may be advantageously substrate mobilization and utilization, or to a reduction in PE. approached by analyzing how they modify information processing GRA within the brain. Central to adaptive information processing as expressed in the mammalian brain, are the cerebral neocortex and associative learning. In both fields, new perspectives are N90-12164# Army Research Inst. of Environmental Medicine, emerging. In particular, information processing in sensory neocortex Natick, MA. involves the operation of active learning processes which transform HEATSTROKE PATHOPHYSIOLOGY THE ENERGY receptive fields. These and related findings provide a basis for DEPLETION MODEL Report, May - Jun. 1989 understanding the functional role of sensory cortical physiological ROGER W. HUBBARD 12 Jun. 1989 42 p plasticity and for a between physiological plasticity and (AD-A212156 USARIEM-M59-89) Avail: NTlS HC A03/MF A01 adaptive information processing in the cerebral cortex. GRA CSCL 06/ 10 This symposium focuses on exertional heatstroke, with N90-12167# Army Aeromedical Research Lab., Fort Rucker, emphasis on predisposing factors, clinical observations, diagnosis, AL. treatment and recovery. The serious challenge to cardiovascular VISUAL ACUITY AND STEREOPSIS WITH NIGHT VISION stability presented by exercise hyperthermia and some aspects of GOGGLES Final Report regulatory failure were reviewed in the introduction. The intent of ROGER W. WILEY Jun. 1989 30 p this review, to describe how heat stress is translated into heat (AD-A211552; USAARL-89-9) Avail: NTlS HC AO3/MF A01 strain at the cellular level, is not to downplay the seriousness of CSCL 1715 the systemic condition. If we are successful, this may stimulate Measurements of visual performance (stereopsis and visual further interest on the impact of heat on the cell as a model for resolution) were acquired to compare results achieved using other factors which alter membrane integrity and permeability, lead unaided monocular and binocular viewing, monocular and binocular to new experimental paradigms, and improve the diagnosis and viewing with the AN/PVSdA night vision goggles, and models A treatment of other disorders such as toxic, hypovolemic or ischemic and B of the AN/PVS-7 biocular night vision goggles. All of the shock. This review may also stimulate interesting research goggles were equipped with 2nd generation tubes. Using a modified regarding more subtle threats to homeostasis such as chronic Howard-Dolman apparatus to assess stereopsis, all of the exercise, hypohydration and thirst, ion imbalance, and goggle-assisted thresholds were very much larger than deprivation. We have discussed the relationship of this concept to stereoscopic thresholds achieved with unaided binocular vision. carbohydrate metabolism, thirst, and the cellular aspects of heat Statistical analysis of the results indicated that stereopsis through

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night vision goggles, regardless of the model or viewing condition, N90-12170# State Univ. of New York, Buffalo. Dept. of is essentially eliminated and equivalent to the threshold obtained Psychology. with unaided monocular viewing. In comparison, spatial resolution CELLULAR AND MOLECULAR MECHANISMS OF HIGH capability with all of the goggle systems is superior to performance PRESSURE INOTROPY IN CARDIAC MUSCLE Annual Report, with unaided vision. In agreement with previously published data, 1 Aug. 1988 - 31 Jul. 1989 visual acuity with the goggles is approximately 20150, but only for PERRY M. HOGAN and STEPHEN R. BESCH 1 Aug. 1989 high contrast targets and simulated full moon ambient light levels. 20 P As light levels decrease to quarter moon conditions or target (Contract NO001 4-88-K-0550; RR04108) contrasts are reduced to more realistic values, visual spatial (AD-A211695) Avail: NTlS HC A03/MF A01 CSCL 06/10 resolution with the goggles is much poorer. For infantry use, any Cardiac muscle subjected to increased hydrostatic pressure differences in visual performance between monocular, biocular, from 2 to 150 atmospheres respond with an increase in developed and binocular designs probably are not operationally meaningful. tension, a phenomenon we refer to as high pressure inotropy GRA (HPI). Experiments were performed on papillary muscles isolated from adolescent rabbit hearts to test the possibility that HPI is due to a preferential action of pressure to partially inhibit the activity of the sodium-potassium pump of the cell membrane leading N90-12168# Central Inst. for the Deaf, Saint Louis, MO. to calcium accumulation through reduced sodium-calcium BINAURAL MASKING: AN ANALYSIS OF MODELS Final exchange. Ouabain, a cardiac glycoside known to inhibit pump Technical Report, 15 Jul. 1986 - 14 Mar. 1989 activity, prevented the development of HPI when applied before ROBERT H. GILKEY 1 Aug. 1989 15 p pressure was increased. Both ouabain and pressure altered the (Contract AF-AFOSR-0298-86 AF PROJ. 231 3) time course of mechanical restitution and the development of the (AD-A211578; AFOSR-89-1164TR) Avail: NTlS HC AO3/MF A01 resting state contraction in a similar manner that could be mimicked CSCL 0518 by a computer model when the calcium extrusion ordinarily The overall goal of this program of research is to specify the occurring during each cardiac cycle was substantially retarded. processes used by the auditory system to detect signals presented Finally, we reported on progress made to develop a in noisy backgrounds. A wide variety of experimental approaches microfluorimeter for measuring cytosolic calcium in single cardiac were used to examine these processes. The data suggest that myocytes under hyperbaric conditions. GRA subjects often detect the signal as a change in the spectralltemporal pattern of stimulus information. These results N90-12171# Air Force Occupational and Environmental Health conflict with the classical models of simple auditory masking that Lab., Brooks AFB, TX. suggest that subjects restrict their analysis to a narrow frequency BASELEVELMANAGEMENTOFRADIOFREQUENCY band and a brief temporal window. Quantitative models of the RADIATION PROTECTION PROGRAM Flnal Report process that compares information across spectral/temporal STEVEN E. RADEMACHER and NOEL D. MONTGOMERY Apr. regions were developed, which combine excitatory and inhibitory 1989 98 p components. While it has traditionally been assumed that quite (AD-A211787; AFOEHL-89-023RC0111DRA) Avail: NTlS HC different mechanisms govern monaural and binaural masking A05lMF A01 CSCL 0617 phenomena, very similar models were successfully applied to the AFOEHL developed this report to assist the base level two sets of data. Other significant results include a more complete aerospace medical team manage their radio frequency radiation description on internal noise processes, evidence that the external protection program. This report supersedes USAFOEHL Report masker is not cancelled by the binaural processor, empirical and 80-42. A Practical R-F Guide for BEES. GRA theoretical evaluations of the efficiency of psychophysical procedures, and hardware and software developments to aid N90-12172# Deutsche Forschungs- und Versuchsanstalt fuer psychoacoustic research. Overall, the work examined issues and Luft- und Raumfahrt, Cologne (Germany, F.R.). Inst. fuer models of contemporary interest and thus has implications for Flugmedizin. auditory theory in general and for the study of auditory pattern STUDIES ON PREDICTING THE RESYNCHRONIZATION OF analysis and auditory masking in specific. GRA THE CIRCADIAN SYSTEM AFTER TRANSMEDIAN FLIGHTS Ph.D. Thesis - Technische Hochschule, Aachen MICHAEL RIPKENS Feb. 1989 122 p In GERMAN; ENGLISH summary Report will also be announced as translation N90-12169# Retina Foundation, Boston, MA. Eye Research (ESA-UT-1177) Inst. (DFVLR-FB-89-10; ISSN-0171-1342; ETN-89-95307) Avail: EYE MOVEMENTS AND SPATIAL PATTERN VISION Final NTlS HC AO6lMF A01; DFVLR, VB-PL-DO, Postafach 90 60 58, Report, 1 Mar. 1986 - 30 Apr. 1989 5000 Cologne, Federal Republic of Germany, 40 deutsche marks LAWRENCE E. AREND 15 Jul. 1989 12 p Resynchronization in the circadian rhythms of different body (Contract AF-AFOSR-0128-86; AF PROJ. 2313) functions after timeshifts of 6 and 9 hours is studied. Three flight (AD-A211650; AFOSR-89-1151TR) Avail: NTlS HC A03/MF A01 experiments involving eight subjects each were carried out to CSCL 0614 determine whether the speed of adaptation could be predicted Models of lightness and color perception must take account of from the individual rhythm parameters of preflight control days. human color constancy, a tendency for apparent surface color to Significant correlations were found only in a few single cases for be relatively independent of the color and intensity of the some functions. Since, in addition, the consistency grade was too illuminating light source. Observers matched the lightness and small, the hypothesis of a reliable predictiveness of the individual brightnesses of regions in simple and complex achromatic spatial adaptation speed had to be refused. This statement should not patterns. The data showed that the observers’ knowledge of the be generalized, as the number of subjects was too small and the surface reflectances (revealed by lightness matches) was applied procedure did not permit more general conclusions. ESA unaffected by changing brightness of the same surfaces (revealed by brightness matches). In the analogous chromatic experiments, N90-12173* National Aeronautics and Space Administration, observers matched the hue and saturation of patches or the Washington, DC. patches’ apparent surface colors. The observers’ knowledge of AEROSPACE MEDICINE AND BIOLOGY A CONTlNUtNG the surface colors was not as reliable as in the achromatic case. BIBLIOGRAPHY WITH INDEXES (SUPPLEMENT 329) Patches’ hues and saturations matched when their chromaticities Nov. 1989 66 p were approximately the same. Shifts of hue attributable to (NASA-SP-701l(329); NAS 1.21:701 l(329)) Avail: NTlS HC A04; simultaneous color contrast were in the correct direction but too NTlS standing order as PE89-912300, $10.50 domestic, $21.00 small to produce hue constancy. GRA foreign CSCL 0615

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This bibliography lists 184 reports, articles and other documents and physiological information available was encoded as a series introduced into the NASA Scientific and Technical Information of dose-effects and pharmacokinetic equations. Assuming additive System during October 1989. Subject coverage includes: aerospace effects, a mathematical model was proposed for the combined medicine and psychology, life support systems and controlled exposure. Several pharmacokinetic interactions make the received environments, safety equipment, exobiology and extraterrestriallife, dose of the combined pollutants nonadditive, however, and thus and flight crew behavior and performance. Author introduce nonadditivity into the combined model. The model was useful in pointing out the kind of information still needed to make N90-13013"# National Aeronautics and Space Administration. predictions, The model thus serves a mainly heuristic purpose. Ames Research Center, Moffett Field, CA. GRA CARDIOVASCULAR, RENAL, ELECTROLYTE, AND HORMONAL CHANGES IN MAN DURING GRAVITATIONAL N90-13016# Michigan Univ., Ann Arbor. Dept. of Electrical STRESS, WEIGHTLESSNESS, AND SIMULATED Engineering and Computer Science. WEIGHTLESSNESS: LOWER BODY POSITIVE PRESSURE TIME-FREQUENCY FACTORS IN AUDITORY PERCEPTION APPLIED BY THE ANTIGRAVITY SUIT Thesis - Oslo Unlv. Annual Report, 15 Apr. 1988 - 14 Apr. 1989 STEIN E. KRAVIK Oct. 1989 142 p Sponsored in part by GREGORY H. WAKEFIELD 30 Jun. 1989 13 p NAS-NRC, Washington, DC Joint Medical Service, HQ Defense (Contract AF-AFOSR-0193-87; AF PROJ. 231 3) Command, Norway and the Norwegian Research Council for (AD-A211491; AFOSR-89-1081TR) Avail: NTlS HC A02/MF A01 Science and the Humanities CSCL 0614 (NASA-TM-102232; A-89084; NAS 1.1 5:102232) Avail: NTlS HC This research investigates how the human auditory system AOl/MF A01 CSCL 06/19 processes temporal properties of a complex signal across two or Because of their erect posture, humans are more vulnerable more regions of the frequency spectrum. Much of the primary to gravitational changes than any other animal. During standing or research from the original proposal on envelope phase disparity walking man must constantly use his antigravity muscles and his using AM carriers is complete. Several findings are outlined. A two columns, his legs, to balance against the force of gravity. At computer model has also been developed and analyzed to consider the same time, blood is surging downward to the dependent issues of cross-spectral temporal disparities. The model is based portions of the body, draining blood away from the brain and on localization by Colburn, among others. GRA heart, and requiring a series of complex cardiovascular adjustments to maintain the human in a bipedal position. It was not until 12 N90-13017# Air Force Occupational and Environmental Health April 1961, when Yuri Gagarin became the first human being to Lab., Brooks AFB, TX. orbit Earth, that we could confirm man's ability to maintain vital BASE LEVEL MANAGEMENT OF RADIO FREQUENCY functions in space -- at least for 90 min. Nevertheless, man's RADIATION PROTECTION PROGRAM Final Report adaptation to weightlessness entails the deconditioning of various STEVEN E. RADEMACHER and NOEL D. MONTGOMERY Apr. organs in the body. Muscles atrophy, and calcium loss leads to 1989 111 p loss of bone strength as the demands on the musculoskeletal (ADA211759; USAFOEHL-89-023RC0111DRA) Avail: NTlS HC system are almost nonexistent in weightlessness. Because of the AO6/MF A01 CSCL 25/2 lack of hydrostatic pressures in space, blood rushes to the upper Assistance is being developed for the base level aerospace portions of the body, initiating a complex series of cardioregulatory medical team to manage their radio frequency radiation protection responses. Deconditioning during spaceflight, however, first program. This report supersedes USAFOEHL Report 80-42, A becomes a potentially serious problem in humans returning to practical R-F Guide for BEES. GRA Earth, when the cardiovascular system, muscles and bones are suddenly exposed to the demanding counterforce of gravity -- N90-13018# Deutsche Forschungsanstalt fuer Luft- und weight. One of the main purposes of our studies was to test the Raumfahrt, Cologne (Germany, F.R.). Inst. fuer. Flugmedizin. feasibility of using Lower Body Positive Pressure, applied with an BIOCHEMICAL AND PHYSIOLOGICAL CHANGES IN GLIDER antigravity suit, as a new and alternative technique to bed rest PILOTS DURING MULTIHOUR FLIGHTS Thesis - Bonn Unlv. and water immersion for studying cardioregulatory, renal, KLAUS GERECHT Jun. 1989 118 p In GERMAN; ENGLISH electrolyte, and hormonal changes in humans. The results suggest summary Report will also be announced as translation that Lower Body Positive Pressure can be used as an analog of (ESA-TT-1183) microgravity-induced physiological responses in humans. Author (DLR-FB-89-29; ISSN-0171-1342; ETN-89-95838) Avail: NTlS HC AO6/MF A01; DLR, VB-PL-DO, Postfach 40 60 58, 5000 N90-13014# Army Research Inst. of Environmental Medicine, Cologne, Fed. Republic of Germany, 40 Deutsche marks Natick, MA. Nine male glider pilots were studied during 12 multi-hour glider HEAT EXHAUSTION flights. Blood and urine samples were taken before, during and LAWRENCE E. ARMSTRONG 30 Jun. 1989 4 p after each flight. The results revealed a high sympathetic, (AD-A212128; USARIEM-M61-89) Avail: NTlS HC A01 /MF A01 adrenomedullary and adrenocortical activity. Findings included a CSCL 06/10 reduction in numbers of eosinophils, changes in blood lipid fractions Heat exhaustion is the most common heat illness, among due to induced lipolysis and an elevation of blood sugar soldiers and athletes. This manuscript is written in an ask the concentrations during the flight, going back to normal shortly after expert format, per request of the journal editor, to describe heat landing. Excretion of adrenaline was highest during the preflight exhaustion for the athletes and practitioner. This manuscript period showing a high level of anticipatory stress, followed by describes the signs/symptoms, physiologicalcause, treatment, and moderate reductions during the flight as opposed to increasing measures which can be taken to prevent heat exhaustion. GRA excretion rates of noradrenaline and 17-hydroxycorticosteroids. This pattern is related to increasing fatigue with length of flight. N90-13015# Health Effects Research Lab., Research Triangle Subsequently loss of weight and elevated packed cell volumes Park, NC. Neurotoxicology Div. were noted. Reduced serum potassium concentrations associated EFFECTS OF ATMOSPHERIC MIX AND TOXIC FUMES ON with more alkaline urine are sequels of hyperventilation, a common MILITARY PERFORMANCE condition in pilots under flight stress. ESA VERNON A. BENIGNUS 1989 85 p (PB89-223630; EPA/600/D-89/060) Avail: NTlS HC AO5/MF N90-13019# Deutsche Forschungsanstalt fuer Luft- und A01 CSCL 06/16 Raumfahrt, Cologne (Germany, F.R.). Inst. fuer Flugmedizin. The individual and combined neurobehavioral effects of carbon EFFECTS OF A TIME ZONE SHIFT OF NINE HOURS ON THE monoxide, hydrogen cyanide, carbon dioxide and hypoxic hypoxia CIRCADIAN RHYTHMS IN COCKPIT AIRCREW MEMBERS ON were studied. The literature of the effects of combined exposures LONGHAUL FLIGHTS Ph.D. Thesis - Tech. Hochschule were covered. This is a relatively sparse literature. The empirical Aachen

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SlLKE RUTH HASENCLEVER Jun. 1989 94 p In GERMAN N90-13022# Arizona State Univ., Tempe. Coll. of Liberal Arts ENGLISH summary Report will also be announced as translation and Sciences. (ESA-TT-1185) PREDICTION OF THERMAL STRESS CASUALTIES Final (DLR-FB-89-31; ISSN-0171-1342; ETN-89-95840) Avail: NTlS Report, Mar. 1986 - Sep. 1988 HC A05/MF A01; DLR, VB-PL-DO, Postfach 40 60 58, 5000 GARY S. KRAHENBUHL, JOSEPH HARRIS, STEFAN H. Cologne, Fed. Republic of Germany, 32 Deutsche marks CONSTABLE (School of Aerospace Medicine, Brooks AFB, TX.), Twelve aircrew members on a flight schedule crossing nine DON W. MORGAN, and JEFFREY K. ALLEN May 1989 44 p time zones are tested for heart rate, temperature, and excretion (Contract F33615-83-D-0602; AF PROJ. 2729) of certain hormone metabolites and electrolytes in the urine over (AD-A212356; USAFSAM-TR-88-23) Avail: NTlS HC AO3/MF a period of seven days. The data is analyzed regarding circadian A01 CSCL 06/10 rhythmicity. The results of this analysis are demonstrated and the Young adult male subjects (n=15) were monitored under possible effects of disturbing body rhythms of members of this conditions featuring various combinations of three factors: work profession are discussed. ESA (rest or treadmill walking at 50 percent V02), clothing (USAF flight suit or USAF flight suit plus the MOPP-IV chemical defense ensemble (CDE)), and environment (in an air conditioned laboratory or outside in the desert summer). Biogenic amine and metabolite N90-13020# Army Research Inst. of Environmental Medicine, responses were determined from timed urine samples using Natick, MA. the high performance liquid chromatography (HPLC) with EXERTIONAL HEATSTROKE AN INTERNATIONAL electrochemical detection. The response profiles of subjects (n=9) PERSPECTIVE. AN INTRODUCTION THE ROLE OF EXERCISE able to persist in their exercise while wearing CDE outdoors in IN THE ETIOLOGY OF EXERTIONAL HEATSTROKE Report, the heat were compared with those (n=6) unable to persist (those May - Jun. 1989 who voluntarily terminated exercise at 50 percent V02 max before ROGER W. HUBBARD 12 Jun. 1989 17 p they had worked for 30 min or reached a rectal temperature of (AD-A212242; USARIEM-M60-8968) Avail: NTlS HC A03/MF 38.5 C (101.3 F)). The data supports the conclusion that subjects A01 CSCL 06/10 who persisted in their exercise did so because they pushed Exertional heatstroke usually occurs among healthy, fit themselves harder. In doing so, they experienced a higher level individuals who are motivated to perform strenuous exercise of physiologicalstress as indicated by the alteration in the excretion because of peer pressure, discipline, or athletic competition. In rates of the biogenic amines and metabolites. GRA fact, exertional heatstroke deaths among high school athletes in the United States ranked only third to head and neck injuries and N90-13023# Science Applications International Corp., McLean, heart failures. The reluctance of race directors to cancel or VA. postpone mass participation road races during periods of severe CALCIUM DISPLACEMENT CAUSED BY ELECTROMAGNETIC heat and humidity, emphasize a continuing need for widespread FIELDS Final Report, 1 Nov. 1982 - 31 Aug. 1989 dissemination of information. The purposes of this symposium are JAMES D. BOND and CAROL A. JORDAN 31 Aug. 1989 9 p to: (1) convey essential information to the members of ACSM (Contract N00014-83-C-0008; RR04108) who are involved in exercise prescription, patient care, or athletic (AD-A212690; SAIC-89/1587) Avail: NTlS HC A02/MF A01 training, and (2) to disseminate recent scientific theories and CSCL 06/7 research concerning exertional heatstroke. GRA The research effort was to determine theoretically a physical basis for the interaction of low intensity externally applied electromagnetic fields with biological tissue. The primary aim of N90-13021# Virginia Univ., Charlottesville. Dept. of Materials the investigation was to establish a molecular basis for the class Science. of interactions commonly referred to as nonthermal effects of SHAPE INSTABILITIES OF PLATE-LIKE STRUCTURES. 1: electromagnetic fields with biological systems. In particular, the EXPERIMENTAL OBSERVATIONS IN HEAVILY COLD biological structure of interest was the plasma membrane since it WORKED IN SITU COMPOSITES had been either directly or indirectly implicated in numerous T. H. COURTNEY (Naval Research Lab., Washington, DC.), J. C. experimental studies. It was demonstrated how a membrane MAUAHN KAMPE, and Y. LENG 1989 12 p Submitted for undergoing a phase transition could qualitatively account for the publication release and/or uptake of divalent calcium ions. A characterization (Contract DAAL03-88-K-0091) of changes in the structure of the membrane/electrolyte interface (AD-A212251; ARO-25177.4-MS-1) Avail: NTlS HC AO3/MF A01 due to field induced changes in enzymatic activity was CSCL 2312 demonstrated. The role of critical phenomena was shown Because hearing protectors attenuate the noise and signal by analytically to be able to account for the unique sensitivity of equal amounts within a given frequency range, reducing both to a biomembranes to weak external field perturbations, and describe level where there is less likelihood of distortion, they often provide alterations in the passive transport of sodium ions in rabbit improved listening conditions. The crossover level from erythrocytes. GRA disadvantage to advantage usually occurs between 80 and 90 dB. However, hearing protectors may adversely affect speech N90-13024# Naval Medical Research Inst., Bethesda, MD. recognition under a variety of conditions. For hearing-impaired RADIO FREQUENCY (13.56 MHZ) ENERGY ENHANCES listeners, whose average hearing levels at 2000, 3000, and 4000 REWARMING FROM MILD HYPOTHERMJA Interim Report Hz exceed 30 dB, certain speech sounds will fall below the level R. L. HESSLINK, R. G. OLSEN (Naval Aerospace Medical Research of audibility. Visual cues may decrease the disadvantage imposed Lab., Pensacola, FL.), L. D. ALLEN, L. D. HOMER, S. B. LEWIS, by hearing protectors. However, the Occlusion Effect, which and V. HARMON 9 May 1989 13 p decreases vocal output when the talker wears protection, adversely (AD-A212703; NMRI-89-46) Avail: NTlS HC A03/MF A01 affects the listener’s speech recognition. The poorest performance CSCL 0615 occurs when both talkers and listeners wear protectors. Hearing The rate of warming after hypothermia depends on the method protectors affect warning signal perception in a similar manner. of rewarming. The effectiveness is compared of radio frequency Again the crossover level seems to be between 80 and 90 dB, (RF) energy against hot (41 C) water immersion (HW) and an and there is greater degradation for individuals with impaired insulated cocoon (IC) for rewarming hypothermic men. Six men hearing. Earmuffs appear to pose greater problems than plugs, fasted overnight and were rewarmed for one hour after attaining and this is especially true of difficulties in signal localization. a 0.5 reduction in rectal temperature (Tre). Tre and esophageal Earplugs produce mainly front-back localization errors, while temperature (Tes) were recorded every 5 minutes with no?-metallic earmuffs produce left-right localization errors as well. Earmuffs thermal probes. The baseline value for Tre and Tes just prior to also drastically impede localization in the vertical plane. GRA rewarming was subtracted from each 5 minute Tre and Tes during

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rewarming to delta Tre and delta Tes. The twelve delta Tes values problem is limited in practical application by expensive and were average for each individual and compared using ANOVA. cumbersome instrumentation. A Scheiner-principle optometer was The superiority of radio frequency energy for rewarming mildly developed for self-evaluation of accommodative state and hypothermic men is shown. GRA biofeedback training. The specific advantages of the new invention over earlier optometers are: (1) simplicity of design; (2) hand held, N90-13025# Naval Medical Research Inst.. Bethesda, MD. portable implementation; (3) light weight; (4) small size; (5) low EFFECTS OF SERIAL WET-DRY-WET COLD EXPOSURE manufacturing cost; (6) the use of a monochromatic light source THERMAL BALANCE, PHYSICAL ACTIVITY, AND COGNITIVE to eliminate the effects of chromatic aberrations in the subject's PERFORMANCE Final Report, Jan. - Mar. 1988 eye; and (6) effectiveness as a training aid. Four prototypes of T. J. DOUBT, R. P. WEINBERG, R. L. HESSLINK, and S. T. the pocket optometer have built and were used to implement AHLERS Mar. 1989 52 p biofeedback training to correct night myopia in 12 Navy aviation (AD-A212704; NMRI-89-35) Avail: NTlS HC A04/MF A01 candidates. All subjects were emmotropic in full light. Training CSCL 06/10 was limited in duration due to the transient nature of subject Thermal balance, physical performance, and cognitive function availability but was reasonably successful in 10 out of the 12 were examined in 7 US. Navy divers who each performed two cases. GRA 7-hour cold exposures while wearing a TLS dry suit with M-400 Thinsulate insulation for thermal protection. The exposures N90-13028# Defence and Civil Inst. of Environmental Medicine, consisted of 2.5 h immersed in 5 C water, followed by 2 h in 5 C Downsview (Ontario). air, and then reentering the water for another 2.5 h. This exposure THEEFFECTOFCONCURRENTSTRENGTH AND paradigm was intended to simulate an operational mission involving ENDURANCE TRAINING ON ELECTROMECHANICAL DELAY, a wet-dry-wet cold exposure. During each exposure, leg exercise MAXIMUM VOLUNTARY CONTRACTION, AND RATE OF at 50 W was performed for the last 30 min of the first immersion FORCE DEVELOPMENT and the first 30 min of the second immersion. In the course of D. G. BELL, 1. JACOBS, D. G. SALE, and J. D. MACDOUGALL one cold exposure, the subject walked 90 min on a treadmill at 2 Aug. 1989 25 p mph during the dry phase, while during the other exposure he (AD-A21331 6; DCIEM-88-RR-33) Avail: NTlS HC A03/MF A01 remained seated at rest for the dry phase. Cognitive function, CSCL 06/10 measured at rest during the midpoint of each dry phase, was The effect of strength and endurance training and their assessed by a battery of 7 NMRI-PA6 tests. GRA combination on electromechanical delays (EMD), rate of force development (RFD) and maximum voluntary isometric contraction N90-13026# National Academy of Sciences - National Research force (MVC) of the knee extensors in male and female subjects is Council, Washington, DC. Committee on Hearing, Bioacoustics compared. The seven male and six female subjects were separated and Biomechanics. into a strength trained group (SG), 3 males and 3 females, and SOUND LOCALIZATION BY HUMAN OBSERVERS an endurance group (EG), 4 males and 3 females. The SG SYMPOSIUM PROCEEDINGS Technlcal Report, 1 Oct. 1988 - performed strength training solely with one leg and combined 30 Sep. 1989 strength and endurance training with the other leg. The EG 1 Jul. 1989 68 p Symposium held in Washington, DC, 14-16 performed endurance training solely in one leg and combined Oct. 1988 strength and endurance training in the other leg. Strength training (Contract NO0014-87-(2-0342) consisted of one legged work on a leg press weight machine. (AD-A212877) Avail: NTlS HC A04/MF A01 CSCL 0614 Endurance training consisted of one legged cycling on a cycle The relation between binaural perception of actual sounds in ergometer. EMD values were derived from electromyographic space and of stimuli presented over headphones, base on activity (EMG) recorded from the vastus laterialis muscle during head-relatedtransfer functions, showed a high correlation. Listeners MVC. MVC forces was measured with a force transducer. Rate of reported that the sound image presented over headphones force development (RFD) was determined form the MVC/time remained internal to the head and not external in space, as with curves using computer software. The EMG, MVC/time curves and natural sound. Head movement, context, bias, experience, and light signal data were simultaneously recorded on FM tape and integration of information across senses remain probable later sampled at 2Khz and stored digitally. The results showed contributions to externalizing headphone-delivered sounds at their that EMD was significantly reduced only in the SG females. Post real-world positions. Sensory information provided by one sense training data showed that the EMD values for the SG females modality may modulate that received by another modality via motor had increased and were not different from initial levels. EMD times and/or efferent control. Interest was expressed in the possibility for the males were significantly shorter that the females. GRA of constructing, and adapting to, super localization systems. The symposium focused on mammalian research but crucial insights were reported on other animal models. Thus there was demonstration that auditory space for the cat may be coded by 53 spatial maps within the superior colliclus. Some human data were presented on the poorer accuracy of locating a source in the BEHAVIORAL SCIENCES presence of multiple sources. Monaural localization, and the coding of sound movement were discussed. GRA Includes psychological factors; individual and group behavior; crew training and evaluation; and psychiatric research. N90-13027# Naval Aerospace Medical Research Lab., Pensacola, FL. A SCHEINER-PRINCIPLE POCKET OPTOMETER FOR A90-13308'# Booz-Allen and Hamilton, Inc., Reston, VA. SELF-EVALUATION AND BIOFEEDBACK ACCOMMODATION SPACE STATION FREEDOM CREW TRAINING TRAINING Interim Report, 1987 - 1988 KAROL J. BOBKO, EDWARD G. GIBSON, SUSAN A. MARONEY, WILLIAM B. CUSHMAN 19 Apr. 1989 14 p and JAMES D. MUCCIO (Booz-Allen and Hamilton, Inc., Reston, (AD-A213171; NAMRL-1344) Avail: NTlS HC A03/MF A01 VA) IAF, International Astronautical Congress, 40th, Malaga, CSCL 20/6 Spain, Oct. 7-13, 1989. 7 p. Most humans tend toward myopia when presented with a (Contract NASW-4300) visual field without sufficient detail to stimulate focusing (IAF PAPER 89-098) Copyright mechanisms. This means that a pilot flying in darkness, or in an The nature of the Space Station Freedom Program presents empty field such as empty sky, will be likely to focus nearer the an array of new and enhanced challenges which need to be windscreen than at the optical infinity required to focus on visual addressed en route to developing an effective and affordabe targets of probable interest. Biofeedback training to counter this infrastructure for crew training. Such an infrastructure is essential

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for the safety and success of the program. The three major self-administered. In order to provide predictive validity for challenges that affect crew training are the long lifetime of the intelligence measurement, the Wechsler Adult Intelligence program (thirty years), the interdependence of successive Scale-Revised and the Wonderlic Personnel Test were obtained increments, and the participation of the three International Partners on the same subjects. Author (Canada, European Space Agency, and Japan) and a myriad of experimenters. This paper addresses these major challenges as N90-12175'# Essex Corp., Orlando, FL. they drive the development of a crew training capability and the A MENU OF SELF-ADMINISTERED MICROCOMPUTER-BASED actual conduct of crew training. Author NEUROTOXICOLOGY TESTS ROBERT S. KENNEDY, ROBERT L. WILKES, LOIS-ANN KUNTZ, A90-13743 and DENNIS R. BALTZLEY Nov. 1988 25 p THE OCCURRENCE OF THE VECTION ILLUSION AMONG (Contract NAS9-17326) HELICOPTER PILOTS WHILE FLYING OVER WATER (NASA-CR-185518; NAS 1.26:185518; EOTR-88-10) Avail: NTlS TIMOTHY J. UNGS (USCG, Kodiak, AK; Wright State University, HC AO3/MF A01 CSCL 0519 Dayton, OH) Aviation, Space, and Environmental Medicine (ISSN This study examined the feasibility of repeated 0095-6562), vol. 60, Nov. 1989, p. 1099-1101. refs self-administration of a newly developed battery of mental acuity Copyright tests. Researchers developed this battery to be used to screen U.S. Coast Guard helicopter pilots were questioned on the the fitness for duty of persons in at-risk occupations (astronauts, occurrence of the vection illusion while flying over water under race car drivers), or those who may be exposed to environmental different light and sea conditions. A total of 267 (79.9 percent) stress, toxic agents, or disease. The menu under study contained pilots completed the study questionnaire. The illusion of vection cognitive and motor tests implemented on a portable was experienced by 248 (92.5 percent) of these pilots. The majority microcomputer including: a five-test core battery, lasting six of the pilots, 209 (84.6 percent), reported that dark rather than minutes, which had demonstrable reliabilities and stability from light visual conditions increased the likelihood of experiencing several previous repeated-measures studies, and also 13 new tests, vection. Vection was considered likely to occur over rough seas lasting 42 minutes, which had appeared in other batteries but had by more pilots, 114 (46.2 percent) than over smooth seas, 81 not yet been evaluated for repeated-measures implementation in (37.8 percent). Several pilots commented that they had responded this medium. Sixteen subjects self-administered the battery over to the illusion with aircraft movement. Author 10 repeated sessions. The hardware performed well throughout the study and the tests appeared to be easily self-administered. A90- 1374 7 Stabilities and reliabilities of the test from the core battery were THE SPOUSAL FACTOR IN PILOT STRESS comparable to those obtained previously under more controlled MARVIN KARLINS (South Florida, University, Tampa, FL), experimental conditions. Analyses of metric properties of the FREDDIE KOH, and LEN MCCULLY (Singapore Airlines, Airmail remaining 13 tests produced eight additional tests with satisfactory Transit Centre, Singapore) Aviation, Space, and Environmental properties. Although the average retest reliability was high, Medicine (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1112-1 115. cross-correlations between tests were low, indicating factorial refs richness. The menu can be used to form batteries of flexible total Copyright testing time which are likely to tap different mental processes and This paper discusses the various occupational and functions. Author nonoccupational stresses faced by commercial aviators, with particular emphasis on the role of the pilot's spouse in the stress N90-12176# North Carolina State Univ., Raleigh. Dept. of management equation. Using findings from scientific studies, it is Electrical and Computer Engineering. suggested that the spouse can be a major social support system THREE DIMENSIONAL OBJECT RECOGNITION EMPLOYING for the aviator and a significant factor in the pilot's ability to deal COMBINED VISUAL AND TACTILE SENSING Final Project effectively with psychosocial stress. It is recommended that airlines Report, 1 Jul. 1985 - 31 Aug. 1988 develop programs that honor (recognize) the spouses for their REN C. LUO, HORNG-HA1 LOH, and PATRICK ROBINSON Dec. contribution to safe aircraft operation (by helping the aviator cope 1988 56 p with stress more effectively) and make both husband and wife (Contract NSF DMC-85-05166) more aware of the special needs, concerns, and challenges that (PB89-219489; NSFIENG-88037) Avail: NTlS HC A04/MF A01 each partner faces in an 'airline marriage'. Author CSCL 0519 The objective of the project was the development of a combined N90-12174'# Essex Corp., Orlando, FL. use of 2-D visual and 2-D tactile information for 3-D object MICROCOMPUTER-BASED TESTS FOR recognition purposes. A conventional video camera is used to REPEATED-MEASURES METRIC PROPERTIES AND obtain the top view of an object. Two tactile sensing arrays mounted PREDICTIVE VALIDITIES on a robot gripper are also used to measure information about ROBERT S. KENNEDY, DENNIS R. BALTZLEY, WILLIAM P. the lateral surfaces of an object. Three dimensional reference DUNLAP, ROBERT L. WILKES, and LOIS-ANN KUNTZ 1 May models are established as a hierarchical decision tree. Measuring 1989 34 p the available features derived from the sensor information of an (Contract NAS9-17326 NSF ISI-85-21282; DAMDl7-85-C-5095) object, a decision tree is traversed to identify and label the sensed (NASA-CR-185517; NAS 1.26:185517; EOTR-89-02) Avail: NTIS object. Developments include: (1) a system capable of performing HC A031MF A01 CSCL 0519 the tasks in an integrated fashion; (2) the construction of an A menu of psychomotor and mental acuity tests were refined. effective and efficient way of discriminating objects; and (3) new Field applications of such a battery are, for example, a study of algorithms for dealing with tactile information developed and the effects of toxic agents or exotic environments on performance implemented in the form of an automatic decision tree generation readiness, or the determination of fitness for duty. The key generator. Author requirement of these tasks is that they be suitable for repeated-measures applications, and so questions of stability and N90-12177# Washington Univ., Seattle. Dept. of Psychology. reliability are a continuing, central focus of this work. After METACOGNITION AND RETRIEVAL FROM LONG-TERM the initial (practice) session, seven replications of 14 micro- MEMORY AT MOUNT EVEREST Final Report, 13 May 1988 - computer-based performance tests (32 measures) were 23 Jun. 1989 completed by 37 subjects. Each test in the battery had previously THOMAS 0. NELSON 27 Jun. 1989 19 p been shown to stabilize in less than five 90-second administrations (Contract AF-AFOSR-0226-88; AF PROJ. 231 3) and to possess retest reliabilities greater than r = 0.707 for three (AD-A211629; AFOSR-89-1113TR) Avail: NTlS HC A031MF A01 minutes of testing. However, all the tests had never been CSCL 0518 administered together as a battery and they had never been Behavioral data were collected from climbers at various

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altitudes on Mount Everest. In contrast to earlier findings that N90-13031# Air Force Inst. of Tech., Wright-Patterson AFB, altitude impairs the acquisition of information into memory, no OH. changes were found in the accuracy or latency of retrieving A COMPARISON OF TWO SUBJECT-CONTROLLED AlTlTUDE information from memory, even at extreme altitudes above 21,000 MEASURES DURING SOMATOGRAVIC ILLUSION EXPOSURE ft (6,400 m). This lack of effect on retrieval occurred for both the M.S. Thesis - Saint Mary’s Unlv. recall and recognition of answers to general information questions JOHN F. THOMPSON May 1989 82 p (e.g., what is the capital of Finland). Self confidence about the (AD-A212528; AFIT/CI/CIA-88-236) Avail: NTlS HC AO5/MF accuracy of recent retrieval was also not affected by altitude. A01 CSCL 06/10 However, the feeling of knowing (i.e., self confidence about The United States Air Force School of Aerospace Medicine upcoming retrieval) declined at extreme altitudes and remained (USAFSAM) has a requirement for a performance evaluation and lower even after return to Kathmandu. This pattern of results is comparison of two subject-controlled attitude indicators during close to opposite of the pattern obtained when the independent exposure to the somatogravic or posturogravic illusion. This illusion variable is alcohol intoxication and the same test battery is is well known for giving aircraft pilots a false sensation of excessive employed. These and related results are described in an attempt pitch-up during take-off. With a lack of visual stimuli, the pilot to give a relatively comprehensive picture of the climbers’ misinterprets the resultant gravitoinertial force vector as performance, and suggestions are offered for future research. approximating the vertical force vector of gravity. Accidents occur GRA when pilots adjust to what they feel is level flight, when they are, in fact, pitched down toward the ground. The USAFSAM Vertifuge (spatial disorientation device) was used to generate this illusion in 16 subjects (8 experienced pilots and 8 nonpilots) by varying N90-13029# Yale Univ., New Haven, CT. School of Medicine. gravitoinertial and actual (cabin) pitch positions. Each subject rode FEAR-POTENTIATED STARTLE AS A MODEL SYSTEM FOR the Vertifuge twice. During one session, the subject used a ANALYZING LEARNING AND MEMORY Annual Report, 1 Jul. canopy-mounted downpointer to estimate position in space relative 1988 - 30 Jun. 1989 to the ground, and in other session the subject used a MICHAEL DAVIS 25 Jul. 1989 7 p joystick-controlled inside-out aircraft attitude indicator. As expected, (Contract AF-AFOSR-0336-87; AF PROJ. 2312) the results clearly indicate that the canopy-mounted downpointer (AD-A212131; AFOSR-89-1221TR) Avail: NTlS HC AO2/MF A01 is better at quantifying the somatogravic illusion in this Vertifuge CSCL OW8 study. Furthermore, it is apparent that there are no significant Previous research has shown that the acoustic startle response, differences in performance between pilots and nonpilots using a simple reflex mediated by four in the brainstem and either device. GRA spinal cord, can be increased when elicited in the presence of a light previously paired with a footshock. This fear-potentiatedstartle N90-13032# New York Univ., New York. Dept. of Psychology. effect can be selectively blocked by drugs that decrease anxiety THREE STAGES AND TWO SYSTEMS OF VISUAL in humans as well as by lesions of the central nucleus of the PROCESSING amygdala, an area of the brain known to be critical for fear. This GEORGE SPERLING 1989 35 p year it was found that local infusion of N-methyl-D-aspartate (Contract AF-AFOSR-0140-88; AF PROJ. 231 3) (NMDA) selective antagonists such as AP5 or CPP completely (AD-A212670; AFOSR-89-1131TR) Avail: NTlS HC A03/MF A01 block the acquisition of fear-potentiated startle. This effect could CSCL 20/6 not be attributed to a decrease in shock sensitivity or vision and Three stages of visual processing determine how internal noise did not occur when these compounds were infused into the appears to an external observer: light adaptation, contrast gain . These data indicate that an NMDA-dependent control, and a postsensory/decision stage. Dark noise occurs prior mechanism in the amygdala is involved in fear conditioning and to adaptation, determines dark-adapted absolute thresholds, and that fear-potentiated startle may provide an excellent behavioral mimics stationary external noise. Sensory noise occurs after dark model system to analyze cellular and biochemical mechanisms of adaptation, determines contrast thresholds for sine gratings and learning and memory. GRA similar stimuli, and mimics external noise that increases with mean luminance. Postsensory noise incorporates perceptual, decision, and mnemonic process. It occurs after contrast-gain control and mimics external noise that increases with stimulus contrast (i.e., N90-13030# California Univ., San Diego. Dept. of multiplicative noise). Dark noise and sensory noise are frequently . specific and primarily affect weak signals. Only postsensory noise ELECTROPHYSIOLOGICAL STUDIES OF VISUAL ATTENTION significantly affects to strong signals, and it has constant power AND RESOURCE ALLOCATION Final Report, 1 Jun. 1986 - 31 over a wide spatial frequency range in which sensory noise varies May 1989 enormously. GRA STEVEN A. HILLYARD, G. R. MANGUN, and S. J. LUCK 30 Aug. 1989 48 p N90-13033# Southeastern Center for Electrical Engineering (Contract N00014-86-K-0291; RR04209) Education, Inc., Saint Cloud. FL. (AD-A212287; SDEPL-002) Avail: NTlS HC A03/MF A01 EFFECTS OF TYPE OF RESPONDING ON MEMORY/VISUAL CSCL 0518 SEARCH RESPONDING JUST YES OR JUST NO CAN LEAD The objective of this project was to better understand TO INFLEXIBLE PERFORMANCE Final Report, May - Sep. mechanisms of visual selective attention in humans, both at the 1986 level of perceptual processing and at the level of the underlying ARTHUR D. FISK and PHILLIP L. ACKERMAN Aug. 1989 brain mechanisms. The main approach was to record event related 10 P brain potentials (EPRs) from the intact scalp using multielectrode (Contract F30602-81-C-0193) arrays. Selective attention to stimulus location was found to (AD-A212764; AFHRL-TR-88-75) Avail: NTlS HC A02/MF A01 enhance short latency brain evoked activity, analysis of current CSCL 0518 source densities indicated that visual inputs were subject to Interactions of stimulus consistency and type of responding attentional control at or before the level of the pre-striate occipital were examined during perceptual learning. Subjects performed cortex. Stimuli patterns of early sensory modulation were found hybrid memory-visual search tasks over extended consistent and during spatially focussed attention to rapid sequences of unilateral varied mapping process. Response conditions required subjects stimuli, to single stimuli occurring at precued locations, and to to respond to both the presence and absence of a target, only bilateral stimulus arrays. Applications of these techniques for when a target is not present. After training, the subjects were evaluating how human operators allocate their attention to visual transferred to a different response condition. The results indicate displays are discussed. GRA that: (1) performance on search tasks with stimuli that are variably

53 53 BEHAVIORAL SCIENCES mapped shows no qualitative changes attributable to manipulation A90-13269# of response format; (2) improvement due to consistent mapping MODULAR AELR SYSTEM TESTBED FOR DEVELOPMENT AND (CM) practice is attenuated in the no-only response condition; (3) IMPLEMENTATION OF AUTOMATION AND ROBOTICS yes-only CM training attenuates the subjects' ability to transfer to ELEMENTS WITHIN FUTURE ORBITAL SYSTEMS no-only responding; and (4) yes/no CM training leads to the E. SCHMIDT and K.-P. LUDWIG (MBB-ERN0 Raumfahrttechnik greatest improvement and transfer when compared with other GmbH, Bremen, Federal Republic of Germany) IAF, International responding conditions. The practice and transfer data support and Astronautical Congress, 40th. Malaga, Spain, Oct. 7-13, 1989. 6 extend previous research investigating effects of response set in p. refs memory/visual search and help to delineate factors that facilitate (IAF PAPER 89-036) or inhibit reduction of load effects in memory and visual search. A study has been made of the automation and robotics (A&R) GRA elements needed to operate the experiment facilities of the Columbus Free Flying Laboratory during the free flying mode and to support the astronaut in the Columbus Attached Laboratory. A N90-13034# Air Force Human Resources Lab., Brooks AFB, potential A&R concept alternative for the payload operation within TX. Manpower and Personnel Div. the Attached Laboratory is described, and the system definition of INDIVIDUAL DIFFERENCES IN ASSOCIATIVE LEARNING AND a modular A&R testbed as a tool for developing, optimizing, and FORGElTING Interim Report, Nov. 1985 - Nov. 1988 verifying automation concepts in realistic simulations and tests is PATRICK C. KYLLONEN and WILLIAM C. TIRRE Aug. 1989 outlined. V.L. 36 P (ADA212765; AFHRL-TP-89-46) Avail: NTlS HC A03/MF A01 A90-13272# CSCL 05/8 A NEW METHOD FOR AUTONOMOUS RETRIEVAL OF A Individual differences in retention were examimed, with SATELLITE USING A VISUAL SENSOR AND A MANIPULATOR particular emphasis on its relationship with item-specific learning SHINSUKE AZUMA, ICHIRO NAKATANI, and KEIKEN NlNOMlYA speed, general learning speed, and general cognitive factors. Young (Institute of Space and Astronautical Science, Sagamihara, adults (N=710) were taught 13 name number pairs to varying Japan) IAF, International Astronautical Congress, 40th, Malaga, successive success criteria using an item dropout procedure to Spain, Oct. 7-13, 1989. 9 p. refs ensure equal learning. Subjects were then taught re-pairings to (IAF PAPER 89-041) Copyright varying criteria, in an A-B, A-Br design, so as to produce a range An autonomous satellite retrieval experiment using an onboard of forgetting conditions. Subjects then were asked to recall and manipulator and a visual sensor has been studied. It is shown relearn the original pairs. Item-specific learning speed predicted that attitude motion of a torque-free, asymmetric rigid body is retention and reacquisition speed: The fastest learners, despite approximately described as a superposition of three rotational having the fewest number of study opportunities, remembered more motions of constant angular velocities. Thus, the motion of a and relearned faster. This relationship held over all forgetting particular principal axis of a target satellite nearly stops relative to conditions, and after statistically equating for within-list interference. the end effector of a manipulator, when a chaser satellite and the General learning speed, as indicated by performance on an end of its manipulator make rotational motions of certain constant independent set of items administered in a variety of formats, angular velocities. Besides, a new method is proposed for visual also predicted retention and relearning. To examine the effects of information processing which is necessary for capturing the target other cognitive factors on learning and retention, various satellite. Computer simulation and an experiment have been carried latent-variable path models were fit to the data. Results are out to prove the validity of the proposed scheme. Author contrasted with those of other investigators who, by employing different procedures for equating degree of learning, have A90-13277# concluded that there are no individual differences in retention. THE FLIGHT TELEROBOTIC SERVICER NASAS FIRST Implications for the discrepancy in conclusions are discussed. - OPERATIONAL SPACE ROBOT GRA RONALD K. BROWNING, HARRY G. MCCAIN, and RUTH I. WHITMAN (McDonnell Douglas Space Systems Co., Huntington Beach, CA) IAF, International Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 7 p. 54 (IAF PAPER 89-050) The Flight Telerobotic Servicer (FTS) is a NASA development of an operational space telerobot and supporting systems to be MANSYSTEM TECHNOLOGY AND LIFE used in the assembly and maintenance of the international Space SUPPORT Station Freedom. The functional capabilities of the FTS and some of the unique technical challenges faced in developing the system Includes human engineering; biotechnology; and space suits and are discussed. The architectural approach taken with FTS is protective clothing. described. C.D.

A90-13278# As13261# DEVELOPMENT OF THE 2ND GENERATION SPACE ROBOT INNOVATIVE APPROACHES TO THE DESIGN OF IN NASDA BIOREGENERATIVE LIFE SUPPORT SYSTEMS FOR TSUTOMU IWATA, MlTSUSHlGE ODA, and TAlCHl NAKAMURA ADVANCED MISSIONS (National Space Development Agency of Japan, Tsukuba Space S. H. SCHWARTZKOPF, T. M. OLCOTT, and E. F. LAURSEN Center, Japan) IAF, International Astronautical Congress, 40th, (Lockheed Missiles and Space Co., Inc., Sunnyvale, CA) IAF, Malaga, Spain, Oct. 7-13, 1989. 8 p. refs International Astronautical Congress, 40th. Malaga, Spain, Oct. (IAF PAPER 89-051) Copyright 7-13, 1989. 10 p. refs The research and development on space Automation and (IAF PAPER 89-026) Copyright Robotics at the National Space Development Agency of Japan The design requirements and applications of innovative (NASDA) covers a range of projects, from the Remote Manipulator bioregenerative life support technologies and hybrid bio- System of the Japanese Experimental Module of the International regenerativelphysicochemical technologies to advanced Space Station to the advanced space robotics, that are utilized in manned missions are considered. The processing of atmosphere, the future space activities. The research effort is now concentrated water, and waste is discussed. Food production and the integration on the second generation space robotics which will be used for of biological systems on advanced manned missions are the Orbital Servicing Vehicle and other unmanned vehicles. The addressed. C.D. characteristics of the second generation space robotics is

54 54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT teleoperation with semiautonomous control, or shared autonomy. Three main facets of man systems are investigated with The role sharing between human operator and the robot will be reference to the Space Station Freedom program: specific hardware the key issue of this advanced space robotics. In this paper, systems that focus on the human element; requirements definition NASDA's scenario for achieving semiautonomous/teleoperational for man-systems integration; and crew interface and operations space robotics is presented. Author analysis. Three key criteria have been identified for selecting individuals to constitute the human system or crew for Space A90-13279'# Jet Propulsion Lab., California Inst. of Tech., Station Freedom missions: aptitude for mission specific skills, Pasadena. motivation, and sensitivity to self and others. Integration of the ADVANCES IN SPACE ROBOTICS human system into the complex engineering and science systems GlULlO VARSl (JPL, Pasadena, CA) IAF, International planned on Space Station Freedom will require the close Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 12 collaboration of engineers, physicians, psychologists, and human p. refs factors experts. Ground-based research and experiments on the (IAF PAPER 89-052) KC-135 aircraft are providing information about how human systems The problem of the remote control of space operations is will function on a space station and how to design other systems addressed by identifying the key technical challenge: the to interact with the crew. A laboratory for further research will be management of contact forces and the principal performance provided onboard Space Station Freedom. C.E. parameters. Three principal classes of devices for remote operation are identified: anthropomorphic exoskeletons, computer aided A90-13302# teleoperators, and supervised telerobots. Their fields of application SIMULATION BY PERSONAL WORKSTATION FOR are described, and areas in which progress has reached the level MAN-MACHINE INTERFACE DESIGN of system or subsystem laboratory demonstrations are indicated. S. BERTHIER, R. MlGlNlAC (AMDBA, Saint-Cloud, France), and Key test results, indicating performance at a level useful for design W. FREl (Dornier GmbH, Friedrichshafen, Federal Republic of tradeoffs, are reported. Author Germany) IAF, InternationalAstronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 8 p. refs A90-13209# (IAF PAPER 89-089) Copyright REQUIREMENTS AND CONCEPTS FOR THE SPACE STATION This paper presents a simulation tool which has been developed REMOTE MANIPULATOR SYSTEM for Man-Machine Interface design study, in the context of the J. H. DUECKMAN, D. M. GOSSAIN, S. S. SACHDEV, and J. A. European EVA Space Suit System development, under contract MIDDLETON (Spar Aerospace, Ltd., Remote Manipulator Systems of ESAIESTEC. The main new point is that this simulation is Div., Toronto, Canada) IAF, International Astronautical Congress, based on a personal workstation, and not on a heavy real-time 40th, Malaga, Spain, Oct. 7-13, 1989. 9 p. computer, as in most simulation centers. It will be used in ESTEC (IAF PAPER 89-069) Copyright to perform low cost simulations of the front part of a manned The Mobile Servicing System (MSS) that is Canada's system, to improve and develop MMI with efficiency. Author contribution to the NASA Space Station Freedom will be used for station assembly, maintenance, and servicing; the MSS's Remote Manipulator System (RMS) is a large robotic system derived from A90-13303# the Space Shuttle's RMS, which will be operated by astronauts DESIGN AND EVALUATION OF MAN-IN-THE-LOOP CONTROL aboard the station. The Freedom RMS is a seven SYSTEM OF JAPANESE EXPERIMENTAL MODULE REMOTE degree-of-freedom manipulator with a central elbow joint as well MANIPULATOR SYSTEM as a three-joint cluster and an end-effector at either end. This K. YAMAWAKI, K. KURAOKA (National Space Development configuration allows the RMS to be relocated by using each end Agency of Japan, Tokyo), M. SHIGEHARA, K. GOMA, T. SUM1 effector alternately as the base or as the of the arm. O.C. (loshiba Corp., Space Programs Div., Kawasaki, Japan) et al. IAF, International Astronautical Congress, 40th, Malaga, Spain, Oct. A90-13300# 7-13, 1989. 7 p. DESIGN GUIDELINES FOR ACCOMMODATION OF ROBOTIC (IAF PAPER 89-090) Copyright AND MANIPULATIVE DEVICES ON SPACE STATION The Japanese Experimental Module Remote Manipulator FREEDOM System (JEMRMS) has two manipulator arms, the main arm (MA) JOHN BOUVIER, DANIEL POL, CURT NEWPORT, JOHN and the small fine arm (SFA). The MA provides the capability of ODONNELL, and JOSEPH PARRISH (Ocean Systems transferring, retrieving, and berthing user payload in the vicinity of the servicing bays. Attached to the MA, the SFA performs dexterous Engineering, Falls Church, VA) IAF, International Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 11 p. refs tasks, such as antenna assembly and replacement of test samples. (IAF PAPER 89-084) Both arms are controlled by a single operator in the Pressurized The purpose of this paper is to address the issues related to Module (PM). The JEMRMS operation console is equipped with the development of the design guidelines necessary for the various man-machine interface equipments such as display accommodation of robotic and manipulative devices used for the and TV monitors, control panels, a keyboard, and a six- assembly, maintenance and servicing of Space Station Freedom. degree-of-freedom hand controller. The vision subsystem Analogies and lessons learned will be drawn from the sub-sea provides the RMS operator with an indirect image of the work and related industries and comparisons will be made to Space monitored by TV cameras mounted on the MAISFA arms, the Station planned tasks and phased configurations. Criteria will be exposed facility, and the PM. A stereoscopic image monitored by discussed in the consideration of humanlmachine compatibility, a stereoscopic TV camera mounted on the SFA's shoulder provides standardization, commonality, kinematics, operational constraints the human operator with three-dimensional visual information and taskhesource matching. Present Space Station robotic considered as the center of the man-in-the-loop control system. technology will be compared to future space activity Several man-in-the-loop experiments were conducted to evaluate requirements. Author the algorithm of the control system and the design of the man-machine interface. A set of significant data have been obtained A90-13301'# National Aeronautics and Space Administration. for the phase C development of the JEMRMS program. C.E. Lyndon B. Johnson Space Center, Houston, TX. HUMAN FACTORS AND PRODUCTIVITY ON SPACE STATION A90-13305# FREEDOM STUDIES ON HABITATION MODULE AND INTERCONNECTING C. S. LEACH, J. W. BROWN, and P. A. SANTY (NASA, Johnson ELEMENTS FOR A FUTURE EUROPEAN SPACE STATION Space Center, Houston, TX) IAF, International Astronautical U. RIEDEL and J. EWALD (MBB-ERN0 Raumfahrttechnik GmbH, Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 7 p. refs Bremen, Federal Republic of Germany) IAF, International (IAF PAPER 89-087) Copyright Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989

55 ~-

54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT

20 p. tainability. And through evaluation, the unit process which (IAF PAPER 89-092) had better be improved by establishment of preventive measures This paper describes the design concepts of the Habitation for safety was also made clear. Author Module (HAB) of a future European space station and the Interconnecting Element (ICE), which will allow the architectural A90-13615# built-up of several elements forming the configuration of an orbital A STUDY ON CULTURING MODULES FOR CELSS IN LUNAR station. Special attention is given to the key requirements for the BASE HAB and ICE designs and to their overall configurations, with KAZUO SEZAKI, SHlNJl NISHIZAKI, SHOJI YAMAZAKI, YASUO special attention given to the human factors and safety aspects MIYATA, YOlCHl SEKl (Ishikawajima-Harima Heavy Industries Co., of the system. Consideration is also given to the HAB and the Ltd., Tokyo, Japan) et al. IAF, InternationalAstronautical Congress, ICE subsystems; the internal architecture of HAB; the development, 40th, Malaga, Spain, Oct. 7-13, 1989. 9 p. test, and ground support of HAB; and the key technologies involved (IAF PAPER 89-576) Copyright in the HABACE. Design diagrams of the HAB and ICE are A feasibility study is reported on a plant culture subsystem for included. IS. covering food supply and oxygen recycling through photosynthesis. The subsystem is a part of the Closed Ecological Life Support A90-13306'# Lockheed Engineering and Sciences Co., Houston, System (CELSS) on a lunar base. Plant culture modules have TX. been conceived that measure 4.5 m in diameter by 15 m in length. USING COMPUTER GRAPHICS TO DESIGN SPACE STATION Internally the modules are arranged in tiers of hydroponic beds, FREEDOM VIEWING provided with a controlled environment including artificial B. S. GOLDSBERRY, B. 0. LIPPERT, S. D. MCKEE (Lockheed illumination, and equipped with a robot for unattended culture of Engineering and Sciences Co., Houston, TX), J. L. LEWIS, JR., wheat, rice, potato, sweet potato, soybean, leaf lettuce, and and F. E. MOUNT (NASA, Johnson Space Center, Houston, TX) spinach. The mean sustenance capability per module is 1.7 IAF. InternationalAstronautical Congress, 40th, Malaga, Spain, Oct. persons. Thus, five modules should suffice to sustain eight persons 7-13, 1989. 5 p. on a lunar base. C.D. (IAF PAPER 89-093) An important aspect of planning for Space Station Freedom at A90-13616# the United States National Aeronautics and Space Administration APPLICATION OF TUBULAR PHOTO-BIOREACTOR SYSTEM (NASA) is the placement of the viewing windows and cameras for TO CULTURE SPlRULlNA FOR GAS EXCHANGE AND FOOD optimum crewmember use. Researchers and analysts are PRODUCTION IN CELSS evaluating the placement options using a three-dimensional MITSUO OGUCHI. KElJl NITTA, KOJl OTSUBO (National graphics program called PLAID. This program, developed at the Aerospace Laboratory, Chofu, Japan), ATSUHIRO SHIMADA. NASA Johnson Space Center (JSC), is being used to determine KAZUO MlYAZAKl (Tonen Corp., Corporate Research and the extent to which the viewing requirements for assembly and Development Laboratory, Saitama, Japan) et al. IAF, International operations are being met. A variety of window placement options Astronautical Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 9 in specific modules are assessed for accessibility. In addition, p. refs window and camera placements are analyzed to insure that viewing (IAF PAPER 89-577) Copyright areas are not obstructed by the truss assemblies, The experimental apparatus of a closed algal cultivation system externally-mounted payloads, or any other station element. has been developed, using Spirulina for continuous 02 and food Other factors being examined include anthropometric design production as well as C02 removal. In early experiments, it was considerations, workstation interfaces, structural issues, and not possible to keep Spirulina culture in good conditions for a mechanical elements. Author long time due to cell adhesion to the reactor wall and the hollow fibers. To solve this problem a cultivation reactor and gas separator of improved design were developed. The new reactor is made of A90-13613# a semitransparent flexible teflon tube of 6 mm bore. In order to OXYGEN SEPARATION SYSTEM OF RESIDENTIAL SPACE AT achieve the high efficiency of light energy supply and to obtain THE LUNAR BASE the heat for culture from lamp irradiation, the teflon tube is coiled YASUFUMI UEDA, NAOAKI IZUTANI, and HIROYASU around a fluorescent lamp as the light source. Separation of YAMAMOTO (Daikin Industries, Ltd., Mechanical Engineering generated 02 gas is conducted with a hydrophobic microporous Laboratory, Sakai, Japan) IAF, International Astronautical polytetrafluoroethylenetube module through which the cultivation Congress, 40th, Malaga, Spain, Oct. 7-13, 1989. 7 p. solution flows, thus preventing algae adhesion. The newly designed (IAF PAPER 89-574) Copyright tubular photobioreactor used in the batch culture experiment is With the aim of developing the lunar resources, helium-3, the found to be satisfactorily applicable to 02 and food production. scheme to build a lunar base has been advanced. The development C.E. of the Closed Ecological Life Support System (CELSS) is important for this scheme of building a lunar base. The investigations of the A90-13618# oxygen separation methods, selection of the suitable oxygen A FOOD/NUTRIENT SUPPLY PLAN FOR LUNAR BASE CELSS separation methods, and the determination of the equipment Y. MIDORIKAWA, T. FUJI1 (JGC Corp., Tokyo, Japan), M. TERAl specifications are presented in this paper. Author (Tokyo Institute of Science and Technology, Japan), K. OMASA (National Institute for Environmental Studies, Tsukuba, Japan), and A90-13614# K. NI'ITA (National Aerospace Laboratory, Tokyo, Japan) IAF, STUDY ON THE NITROGEN FIXATION SYSTEM REQUIRED International Astronautical Congress, 40th, Malaga, Spain, Oct. FOR PLANT CULTURE IN A LUNAR BASE 7-13, 1989. 8 p. refs TORU NUMAGUCHI, KATSUTOSHI KlKUCHl (Toyo Engineering (IAF PAPER 89-579) Copyright Corp., Research Center, Mobara, Japan), SYOKO YAMADAYA, A nutrient recommendation for lunar base has been presented, YUJl SHINDO (National Chemical Laboratory for Industry, Tsukuba, based on the amino acid requirement. A plan for nutrient supply Japan), and KElJl NI'ITA (National Aerospace Laboratory, Chofu, and plant farming for the 8-16 crew lunar base is discussed. The Japan) IAF, International Astronautical Congress, 40th, Malaga, bed area for plant cultivation is restricted to less than 40 sq m Spain, Oct. 7-13, 1989. 7 p. refs per person, thus supplying enough food for the crews from the (IAF PAPER 89-575) Copyright nutrition point of view. To satisfy the essential nutrient elements The paper proposes the optimal process for the nitrogen fixation required, mushroom cultivation for supply of vitamin 82, system for eight crews in a lunar base. Evaluation was carried transportation of lime from earth for calcium, and recovery of out by the MUF method from the overall viewpoint of safety, sodium from human urine for sodium chloride are considered. In compactness, efficiency, realizability, operability, and main- such an isolated and closed environment as a lunar base, not

56 54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT only nutrient sufficiency but also the pleasure of eating should be GERD HlRZlNGER (DLR, Cologne, Federal Republic of Germany) considered. It is necessary to generate as much food as possible Aerospace America (ISSN 0740-722X), vol. 27, Aug. 1989, p. from a limited number of plant species. C.E. 42-46. Copyright AW-l3619# The proposed telerobotic technology experiment, Rotex, is PLANT CULTURAL SYSTEM INCORPORATED INTO CELSS described. Rotex is a six-axis robot in a spacelab rack; it has M. KIYOTA, Y. KITAYA, I. AIGA, K. YABUKI (Osaka Prefecture, force and torque sensors, range finders, and a stereo camera. University, Sakai, Japan), M. FUJI1 (Yanmar Technical Center, Rotex capabilities include assembly and servicing tasks and Kyoto, Japan) et al. IAF, International Astronautical Congress, grasping of floating objects. Also the robot has slow and fast 40th, Malaga, Spain, Oct. 7-13, 1989. 6 p. refs modes of operation. The design and operation of the robot's gripper (IAF PAPER 89-580) Copyright and laser range finders are examined; a diagram of the Rotex's To confirm the possibility of plant cultivation under microgravity gripper is presented. Teleoperation from the ground is discussed. in space, the growth of lettuce and turnips cultivated upside down I.F. was investigated. Rooting beds were arranged above and below an array of fluorescent lamps. Plants were grown normally in the A90-15426" National Aeronautics and Space Administration. lower bed and upside down in the upper beds. The results show Ames Research Center, Moffett Field, CA. no remarkable differences in growth rates and morphological LIFE SCIENCES AND SPACE RESEARCH XXlll(3): NATURAL aspects of the plants in the lower and upper beds. These facts AND ARTIFICIAL ECOSYSTEMS; PROCEEDINGS OF THE mean that phototoropism can overcome geotropism, and that a TOPICAL MEETINGS OF THE 27TH COSPAR PLENARY PPFD of 300 micro-E/sq m/s ensures plant growth regardless of MEETING, ESPOO, FINLAND, JULY 18-29, 1988 gravity direction. Author R. D. MACELROY, ED. (NASA, Ames Research Center, Moffett Field, CA), T. W. TIBBITTS, ED. (Wisconsin, University, Madison), A90-13620# 6. G. THOMPSON, ED. (Alberta Research Council, Edmonton, THE EFFECTS OF AUTOMATION ON WORK IN SPACE Canada), and T. VOLK, ED. (New York University, NY) Meetings LESLIE A. WICKMAN (Lockheed Missiles and Space Co., Inc., sponsored by COSPAR. Advances in Space Research (ISSN Sunnyvale, CA) IAF, International Astronautical Congress, 40th, 0273-1 177), vol. 9, no. 8, 1989, 202 p. For individual items see Malaga, Spain, Oct. 7-13, 1989. 10 p. refs A90-15427 to A90-15447. (IAF PAPER 89-583) Copyright Copyright The nature of the relationship between automation and the The present conference discusses topics in the fields of higher astronaut's work in space is investigated. The approach to this plant growth under controlled environmental conditions, waste study is based on extensive literary research on the topic and oxidation, carbon cycling, and biofermentor design and operation. original data collection from groups cooperating with NASA in the Attention is given to C02 and 02 effects on the development implementation of automation in space. The following issues are and fructification of wheat in closed systems, transpiration during considered: relationship between technology and work in space; life cycle in controlled wheat growth, sources and processing of productivity versus astronaut job satisfaction; and effects of CELSS wastes, waste-recycling in bioregenerative life support, and automation on astronaut skills. Findings on these issues are the effect of iodine disinfection products on higher plants. Also summarized and discussed. C.E. discussed are carbon cycling by cellulose-fermentingnitrogen-fixing bacteria, a bioreactor design with sunlight supply and operations A90-13737 systems for use in the space environment, gas bubble coalescence HEAD COOLING IS DESIRABLE BUT NOT ESSENTIAL FOR in reduced gravity conditions, and model system studies of a PREVENTING HEAT STRAIN IN PILOTS phase-separated membrane bioreactor. O.C. JOHN FRlM (Defence and Civil Institute of Environmental Medicine, Downsview, Canada) Aviation, Space, and Environmental Medicine A90-15427' Utah State Univ., Logan. (ISSN 0095-6562), vol. 60, Nov. 1989, p. 1056-1062. refs CURRENT AND POTENTIAL PRODUCTIVITY OF WHEAT FOR Copyright A CONTROLLED ENVIRONMENT LIFE SUPPORT SYSTEM Liquid-cooled garments (LCGs) are being considered for B. G. BUGBEE and F. B. SALISBURY (Utah State University, reducing heat strain in pilots. While head cooling has been shown Logan) (COSPAR, Plenary Meeting, 27th, Topical Meetings on to be thermally efficient and subjectively desirable, it is technically Life Sciences and Space Research XXlll(3): Natural and Artificial difficult to achieve. A laboratory study was carried out to see if Ecosystems, Espoo, Finland. July 18-29, 1988) Advances in Space head cooling in addition to torso cooling is a necessity. Cooling Research (ISSN 0273-1177), vol. 9, no. 8, 1989, p. 5-15. Research conditions were: control, no fluid circulation; condition VEST, only supported by Utah State University. refs torso cooling; condition HEAD, both torso and head cooling. (Contract NCC2-139) Subjective thermal comfort assessments confirmed the desirability Copyright of head cooling, but performance measurements and physiological Several determinants of crop growth are analyzed to determine measurements of thermal strain showed no statistically significant theoretical and potentially achievable productivity. These include: difference between conditions VEST and HEAD. It was concluded incident photosynthetic photon flux (PPF); percent absorption of that head cooling is desirable but not essential. Author the incident PPF by photo synthetic tissue; photosynthetic efficiency; respiratory carbon use efficiency; and harvest index. A90-14998*# Jet Propulsion Lab., California Inst. of Tech., The effects of optimal environmental and cultural factors on each Pasadena. of these determinants are also investigated. Results indicate that SPACE ROBOTICS IN THE '90s an increase in the percentage of absorbed photons is responsible CARL F. RUOFF (JPL, Pasadena, CA) Aerospace America (ISSN for most of the improvement in wheat yields in an optimal controlled 0740-722X3, VOl. 27, Aug. 1989, p. 38-41, 46. environment. An integrated PPF of 150 mol/sq m per d has Copyright produced 60 g/sq m per d of grain. There is almost a linear The use of telerobots and rovers in space missions is examined. increase in wheat yields with increasing PPF. At intermediate and The functioning of the telerobots and rovers and their proposed equal integrated daily PPF levels, photoperiod had little effect on applications are described. Research developments needed to yield per day or energy efficiency. Decreasing temperature from design robots for specific environments and functions are 23 to 17 deg increased yield per day by 20 percent but increased described. Examples of NASA robotics projects are presented. the life cycle from 62 to 89 days. C.E. I.F. A90-15428 A90-14999# EFFECTOFC02AND02ON DEVELOPMENTAND WEST GERMANY'S FIRST SPACE ROBOT FRUCTIFICATION OF WHEAT IN CLOSED SYSTEMS

57 54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT

M. ANDRE, D. MASSIMINO, J. MASSIMINO (CEA, lnstitut de The analysis includes diagrams illustrating the net photosynthesis Recherche Fondamentale, Saint-Paul-lez-Durance, France), A. response to bilateral lighting of a sparse stand of low assimilate GERBAUD (Institut National de la Recherche Agronomique, Lemna gibba; the effect of stand density on the net photosynthesis Montpellier, France), F. COTE et al. (COSPAR, Plenary Meeting, response to bilateral lighting of high assimilate Lemna gibba; the 27th, Topical Meetings on Life Sciences and Space Research net photosynthesis response to ambient C02 of sparse stands of XXlll(3): Natural and Artificial Ecosystems, Espoo, Finland, July Lemna gibba; and the time course of net photosynthesis and 18-29, 1988) Advances in Space Research (ISSN 0273-1 177), vol. respiration per unit chamber and per unit dry weight of Lemna 9, no. 8, 1989, p. 17-28. Research supported by CNES. refs gibba. C.E. Copyright The cultivation of wheat (Triticum aestivum L.) was performed A90-15431 in controlled environment chambers with the continuous monitoring UTILIZATION OF WHITE POTATOES IN CELSS of photosynthesis, dark respiration, transpiration and main nutrient THEODORE W. TIBBIlTS, SUSAN M. BENNETT, ROBERT C. uptakes. A protocol in twin chambers was developed to compare MORROW, and RAYMOND J. BULA (Wisconsin, University, the specific effects of low 02 and high C02. Each parameter is Madison) (COSPAR, Plenary Meeting, 27th, Topical Meetings on able to influence photosynthesis but different effects are obtained Life Sciences and Space Research XXlll(3): Natural and Artificial in the development, fructification and seed production, because Ecosystems, Espoo, Finland, July 18-29, 1988) Advances in Space of the different effects of each parameter on the ratio of reductive Research (ISSN 0273-1177), vol. 9, no. 8, 1989, p. 53-59. to oxidative cycle of carbon. The first main conclusion is that low Copyright level of 02, at the same rate of biomass production, strongly acts The potential of white potatoes (Solanum tuberosum) as a useful on the rate of ear appearance and on seed production. Ear crop species in a functioning CELSS is investigated. The cultivars appearance was delayed and seed production reduced with a low Denali were grown in a controlled environment room to maximize 02 treatment (about 4 percent). The 02 effect was not mainly yield productivity in terms of grams per unit area per day. due to the repression of the oxidative cycle. The high C02 treatment Environmental response to irradiance and C02 interactions, light (700 to 900 microl/l delayed ear appearance by 4 days, but did duration changes, lightldark cycles, and diurnal temperature not reduce seed production. High C02 treatment also reduced fluctuations is considered. Attempts have been made to obtain transpiration by 20 percent. Two hypothesis were proposed to cultivars selected for long daylengths and for adaptation to high explain the similarities and the difference in the 02 and C02 temperatures. The study of cultural procedures include substrates effects on the growth of wheat. Author and media; continuous harvesting of tubers; and plant spacing and container configuration. The high productivity of nutrious tubers, A90-15429 high harvest index, and low irradiance requirement of the potato UTILIZATION Of SWEET POTATOES IN CONTROLLED plant make it a particularly strong candidate for use in CELSS to ECOLOGICAL LIFE SUPPORT SYSTEMS (CELSS) provide food and oxygen, and to remove C02 for space WALTER A. HILL, PHILIP A. LORETAN, CONRAD K. BONSI, inhabitants. C.E. CARLTON E. MORRIS, JOHN Y. LU (luskegee University, AL) et al. (COSPAR, Plenary Meeting, 27th, Topical Meetings on Life A90-15432' New York Univ., New York. Sciences and Space Research XXlll(3): Natural and Artificial TRANSPIRATION DURING LIFE CYCLE IN CONTROLLED Ecosystems, Espoo, Finland, July 18-29, 1988) Advances in Space WHEAT GROWTH Research (ISSN 0273-1177), vol. 9, no. 8, 1989, p. 29-39, 41. TYLER VOLK (New York University, NY) and JOHN D. RUMMEL refs (NASA, Washington, DC) (COSPAR, Plenary Meeting, 27th, Copyright Topical Meetings on Life Sciences and Space Research XXlll(3): A number of short-term hydroponic studies selected the sweet Natural and Artificial Ecosystems, Espoo, Finland, July 18-29, 1988) potatoes as a potentially important crop for CELSS. Full-term Advances in Space Research (ISSN 0273-1177), vol. 9, no. 8, studies were needed to understand the physiology of storage root 1989, p. 61-64. refs enlargement and to evaluate sweet potato production potential (Contract NCA2-101) for CELSS. In a nutrient film technique (NFT), storage root yields Copyright as high as 1790 g were produced with an edible growth rate of A previously-developed model of wheat growth, designed for up to 66 g/sq m per d and a harvest as high as 89 percent convenient incorporation into system-level models of advanced under greenhouse conditions. Preliminary experiments indicate that space life support systems is described. The model is applied to high yields can be achieved in controlled environmental chambers. data from an experiment that grew wheat under controlled Significant cultivar differences appeared in all systems studied. conditions and measured fresh biomass and cumulated Nutritive composition of storage roots and foliage were similar to transpiration as a function of time. The adequacy of modeling the field grown plants. C.E. transpiration as proportional to the inedible biomass, and an age factor which varies during the life cycle, are examined. Results A90-15430' Hebrew Univ., Jerusalem (Israel). indicate that during the main phase of vegetative growth in the CARBON BALANCE AND PRODUCTIVITY OF LEMNA GIBBA, first half of the life cycle, the rate of transpiration per unit mass A CANDIDATE PLANT FOR CELSS of inedible biomass is more than double the rate during the phase J. GALE (Jerusalem, Hebrew University, Israel), D. T. SMERNOFF of grain development and maturation during latter half of the life (Stanford University, CA), B. A. MACLER, and R. D. MACELROY cycle. Author (NASA, Ames Research Center, Moffett Field, CA) (COSPAR, Plenary Meeting, 27th, Topical Meetings on Life Sciences and A90-15433 Space Research XXlll(3): Natural and Artificial Ecosystems, Espoo, LONG-TERM EXPERIMENTS ON MAN'S STAY IN BIOLOGICAL Finland, July 18-29, 1988) Advances in Space Research (ISSN LIFE-SUPPORT SYSTEM 0273-1177), vol. 9, no. 8, 1989, p. 43-52. refs I. 1. GITEL'SON, 1. A. TERSKOV, 8. G. KOVROV, G. M. LISOVSKII, Copyright IU. N. OKIADNIKOV (AN SSSR, lnstitut Biofiziki, Krasnoyarsk, The photosynthesisand productivity of Lernna gibba is analyzed USSR) et al. (COSPAR, Plenary Meeting, 27th. Topical Meetings for CELSS based plant growth. Net photosynthesis of Lemna gibba on Life Sciences and Space Research XXlll(3): Natural and Artificial is determined as a function of incident photosynthetic photon flux Ecosystems, Espoo, Finland, July 18-29, 1988) Advances in Space (PPF), with the light coming from above, below, or from both Research (ISSN 0273-1 177), vol. 9, no. 8, 1989, p. 65-71. refs directions. Light from below is about 75 percent as effective as Copyright from above when the stand is sparse, but much less so with The described experimental system having maxhal possible dense stands. High rates of photosynthesis are measured at 750 closure of material recycling in an ecosystem includins people micromol / sq m per sec PPF and 1500 micromol/ mol C02 at and plants, which was carried out in a hermetically sealed densities up to 660 g fresh weight (FW)/ sq m with young cultures. experimental complex 'BIOS-3', is 315 sq m in volume. The system

58 54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT t included two experimentators and three phytotrons with plants below and above the critical point of water (374 C and 218 kg/sq (total sowing area of 63 sq m). Plants were grown with cm or 21.4 MPa). The effects of oxidation temperature ( 250-500 1 round-the-clock lamp irradiation with 130 W/sq m PAR intensity. C) and residence time (0-120 mn) on carbon and nitrogen and on I The plants' production was food for people. Water exchange of metal corrosion from the reactor material were studied. Almost all ecosystem, as well as gas exchange, was fully closed excluding of the organic matter in the model wastes was oxidized in the liquids and gas samples taken for chemical analysis outside the temperature range from 400 to 500 C, above the critical conditions I system. The total closure of material turnover constituted 91 for water. In contrast, only a small portion of the organic matter percent. Health state of the crew was estimated before, during was oxidized at subcritical conditlons. A substantial amount of and after the experiment. A 5-month period did not affect their nitrogen remained in solution in the form of ammonia at I health. The experiments demonstrate that the closed ecosystem temperatures ranging from 350 to 450 C suggesting that, around ! of 'man-plants' is a prototype of a life-support system for long-term 400 C, organic carbon is completely oxidized and most of the space expeditions. Author nitrogen is retained in solution. The Hastelloy C-276 alloy reactor i corroded during subcritical and supercritical water oxidation. C.E. I A90-15434' National Aeronautics and Space Administration. Ames Research Center, Moffett Field, CA. A90-15437 WASTE RECYCLING ISSUES IN BIOREGENERATIVE LIFE THE C23A - FIRST STEP TO A MONITORING SYSTEM OF I SUPPORT CELSS IN FLIGHT R. D. MACELROY (NASA, Ames Research Center, Moffett Field, CH. LASSEUR (Matra Espace, Velizy-Villacoublay, France), D. ~ CA) and D. WANG (NASA, Ames Research Center; TGS MASSIMINO, J. L. RENOU, and CH. RICHAUD (CEA, Centre Technology, Inc., Moffett Field, CA) (COSPAR, Plenary Meeting, d'Etudes Nucleaires de Cadarache, Saint-Paul-les-Durance, 27th, Topical Meetings on Life Sciences and Space Research France) (COSPAR, Plenary Meeting, 27th, Topical Meetings on XXlll(3): Natural and Artificial Ecosystems, Espoo, Finland, July Life Sciences and Space Research XXlll(3): Natural and Artificial 18-29, 1988) Advances in Space Research (ISSN 0273-1177), vol. Ecosystems, Espoo, Finland, July 18-29, 1988) Advances in Space 9, no. 8, 1989, p. 75-84. refs Research (ISSN 0273-1 177), vol. 9, no. 8, 1989, p. 11 1-1 16. Copyright refs Research and technology development issues centering on the Copyright recycling of materials within a bioregenerative life support system For the past 15 years, the C23A automatic control system has are reviewed. The importance of recovering waste materials for been used to monitor and quantify gases, water, and chemical subsequent use is emphasized. Such material reclamation will compounds for several processes of CELSS. A new version is ' substantially decrease the energy penalty paid for bioregenerative introduced, adapted to space requirements and equipped with the life support systems, and can potentially decrease the size of the latest computing system for remote control, independent system and its power demands by a significant amount. functioning, multiplication of alarms and controls, multiplexing of Reclamation of fixed nitrogen and the sugars in cellulosic materials analyzers, and reliable quality measurements. The architecture of is discussed. Author the computing system comprises three independent functions: acquisiton, monitoring, and supervision. The use of multiplex A90-15435' National Aeronautics and Space Administration. analyzers such as the IRGA mass spectrometer and chemical Ames Research Center, Moffett Field, CA. analyzer, increases measurement accuracy and could facilitate the SOURCES AND PROCESSING OF CELSS WASTES spatialization. The new C23A structure anticipates a complete T. WYDEVEN (NASA, Ames Research Center, Moffett Field, CA), separation between automation in space and control/command J. TREMOR, C. KO0 (NASA, Ames Research Center; TGS on ground. C.E. 1 Technology, Inc., Moffett Field, CA), and R. JACQUEZ (New Mexico State University, Las Cruces) (COSPAR, Plenary Meeting, 27th, A90-15439" National Aeronautics and Space Administration, Topical Meetings on Life Sciences and Space Research XXlll(3): Washington, DC. Natural and Artificial Ecosystems, Espoo, Finland, July 18-29, 1988) THE ROLE OF COMPUTERIZED MODELING AND SIMULATION Advances in Space Research (ISSN 0273-1177), vol. 9, no. 8, IN THE DEVELOPMENT OF LIFE SUPPORT SYSTEM 1989, p. 85-97. refs TECHNOLOGIES Copyright MICHAEL MODELL (Modell Development Corp., Framingham, MA), The production rate and solid content of waste streams found PEGGY EVANICH (NASA, Washington, DC), CHAU-CHYUN CHEN, in a life support system for a space habitat (in which plants are SELlM ANAVI, and JEFF MA1 (Aspen Technology, Inc., Cambridge, grown for food) are discussed. Two recycling scenarios, derived MA) (COSPAR, Plenary Meeting, 27th, Topical Meetings on Life from qualitative considerations as opposed to quantitative mass Sciences and Space Research XXlll(3): Natural and Artificial and energy balances, tradeoff studies, etc., are presented; they Ecosystems, Espoo, Finland, July 18-29, 1988) Advances in Space reflect differing emphases on and responses to the waste stream Research (ISSN 0273-1177), vol. 9, no. 8, 1989, p. 121-131. formation rates and their composition, as well as indicate the refs required products from waste treatment that are needed in a life Copyright support system. The data presented demonstrate the magnitude Computerized modeling and simulation (CMAS) is a tool that I of the challenge to developing a life support system for a space can greatly reduce both the time and cost of technology habitat requiring a high degree of closure. Author development. CMAS refers to computer methods for correlating, storing, and retrieving property data for chemical species and for A90-15436' Niigata Univ. (Japan). solving the phenomenological equations of physical/chemical SUBCRITICAL AND SUPERCRITICAL WATER OXIDATION OF processes. Furthermore, process conditions based on properties CELSS MODEL WASTES of materials, mass, and energy balances; equipment sizing based Y. TAKAHASHI (Niigata University, Japan), T. WYDEVEN (NASA, on rate processes; and the governing equations for unit operations Ames Research Center, Moffett Field, CA), and C. KO0 (NASA, can be determined using CMAS. CMAS systems can be used to Ames Research Center; TGS Technology, Inc., Moffett Field, CA) evaluate an LSS process with minimal requirements for laboratory (COSPAR, Plenary Meeting, 27th, Topical Meetings on Life experimentation. A CMAS model is presented for a vapor Sciences and Space Research XXlll(3): Natural and Artificial compression distillation system(VCD) for reclaiming water from Ecosystems, Espoo, Finland, July 18-29, 1988) Advances in Space urine. C.E. Research (ISSN 0273-1177), vol. 9, no. 8, 1989, p. 99-110. refs Copyright A90-15444 A mixture of ammonium hydroxide with acetic acid and a slurry DESIGN FOR A BIOREACTOR WITH SUNLIGHT SUPPLY AND of human feces, urine, and wipes were used as CELSS model OPERATIONS SYSTEMS FOR USE IN THE SPACE wastes to be wet-oxidized at temperatures from 250 to 500 C, Le. ENVIRONMENT

59 54 MANBYSTEM TECHNOLOGY AND LIFE SUPPORT

KEI MOR1 (Keio University, Yokohama, Japan), HARUHIKO OHYA, the design to eliminate these resistances are proposed. Cell growth KANJI MATSUMOTO (Yokohama National University, Japan), was obtained in the fermenter using Saccharomyces cerevisiae HlROYUKl FURUUNE, KYOKO ISOZAKI (La Foret Engineering showing that this concept is capable of sustaining cell growth in and Information Service Co., Tokyo, Japan) et al. (COSPAR, the terrestrial simulation. Author Plenary Meeting, 27th, Topical Meetings on Life Sciences and Space Research XXlll(3): Natural and Artificial Ecosystems, Espoo, A90-15800 Finland, July 18-29, 1988) Advances in Space Research (ISSN TELEOPERATORS 0273-1177), vol. 9, no. 8, 1989, p. 161-168. refs WILLIAM R. UTTAL (Arizona State University, Tempe) Scientific Copyright American (ISSN 0036-8733), vol. 261, Dec. 1989, p. 124-129. A photosynthetic bioreactor and a solar light collection system Copyright to support fast cultivation of algae at high densities in the In the absence of fully autonomous robots, machines operated weightlessness of space is presented. Designed for long operation by a person at a distance can carry out tasks in remote or hostile in space without maintenance, the system will be able to filter environments. The fundamental challenge is to design powerful, most of the harmful ultraviolet and infrared radiation from sunlight flexible links between the human operator and the distant machine. and transfer the concentrated visible light through optical fiber The task is shaped as much by human perceptual, cognitive, and cables to illuminate cultivation tanks. Five major components motor abilities as it is by engineering considerations. The prototype operating within a closed system of tank, tubes and monitoring teleoperators described here show that most of the physical devices are discussed: tank illumination subsystem; light supply technology needed for these highly complex and useful subsystem; C02 supply and 02 collection subsystem; culture supply teleoperators is already available. C.E. and separation subsystem; and nutrient supply and recycling subsystem. Results of an experiment using chlorella ellipsoidea to A90-16352 investigate the characteristics of 02-C02 gas exchange, the ROBOTICS AND TELEOPERATION concentration and separation of chlorella, and the dialysis of ionic IAN PARKER Space (ISSN 0267-954X), vol. 5, Nov.-Dec. 1989, salts in the growth medium are presented. C.E. p. 10-12. Copyright A90-15445 The use of telepresence and teleoperation for EVA is examined. CLOSED AND CONTINUOUS ALGAE CULTIVATION SYSTEM The application of robotic technology to microgravity experiments, FOR FOOD PRODUCTION AND GAS EXCHANGE IN CELSS risk reduction for astronauts, and docking procedures is discussed. MITSUO OGUCHI, KOJl OTSUBO, KElJl NIlTA (National Current advances in robotics and the advantages they provide for Aerospace Laboratory, Chofu, Japan), ATSUHIRO SHIMADA, space exploration and research are considered. I.F. SHIGEO FUJI1 (Toa Nenryo Kogyo, Corporate Research and Development Laboratory, Saitama, Japan) et al. (COSPAR, A90-16522 Plenary Meeting, 27th. Topical Meetings on Life Sciences and ACTIVE VIBRATION CONTROL FOR FLEXIBLE SPACE Space Research XXlll(3): Natural and Artificial Ecosystems, Espoo, ENVIRONMENT USE MANIPULATORS Finland, July 18-29, 1988) Advances in Space Research (ISSN T. KOMATSU, M. UENOHARA, S. IIKURA (Toshiba Corp., 0273-1177), vol. 9, no. 8, 1989, p. 169-177. Mechanical Engineering Laboratory, Kawasaki, Japan), H. MIURA, Copyright and 1. SHIMOYAMA (Tokyo, University, Japan) IN: Dynamics of A new cultivation system has been developed to produce algae controlled mechanical systems; Proceedings of the IUTAM/IFAC continuously in a closed condition. Due to high food value, easy Symposium, Zurich, Switzerland, May 30-June 3, 1988. Berlin and digestion, rapid growth, easy harvest, and high utilization efficiency New York, Springer-Verlag, 1989, p. 181-1 92. refs of C02, Spirulina maxima, Spirulina oscillatoria, and Spirulina Copyright subsalsa are used in a liquid culture medium for food production A new dynamic control system for flexible space manipulators and gas exchange in CELSS. These experiments were performed has been developed from the practical viewpoint. The key concept under the following conditions: light intensity at 3,000 to 10,000 is that the local position and torque PD feedback loop at each lux; temperature at 30 C; pH at 8.6 to 10.5; internal pressure at joint should be used for position and structural-vibration control. 0.01 to 0.10 kgflsq cm; 0.D at 10 to 30 percent; and a pumping The manipulator dynamics is derived, and then feedback control speed of 820 to 2,000 ml/rnin. A computer system is set to control is developed using an appropriate potential function. An four operational modes of algae cultivation: ordinary mode, harvest experimental setup using an air-suspended SCARA flexible mode, high pressure mode, and low pressure mode. All data are manipulator is described. The effectiveness of this method has automatically recorded in the computer and transcribed into a been verified by experimental results, adapting it to automatic graph. This new equipment is a primary ground-experiment model payload handling. Author for cultivation of algae under space weightlessness conditions. C.E. A90-16531' New York Univ., New York. THE CASE FOR CELLULOSE PRODUCTION ON MARS A90-15447' Jet Propulsion Lab., California Inst. of Tech., TYLER VOLK (New York University, NY) and JOHN D. RUMMEL Pasadena. (NASA, Life Sciences Div., Washington, DC) IN: The case for PHASE SEPARATED MEMBRANE BIOREACTOR - RESULTS Mars 111: Strategies for exploration - Technical. San Diego, CA, FROM MODEL SYSTEM STUDIES Univelt, Inc., 1989, p. 87-94. refs G. R. PETERSEN, P. K. SESHAN (JPL, Pasadena, CA), and E. H. (Contract NCAZ-101) DUNLOP (Colorado State University, Fort Collins) (COSPAR, (AAS PAPER 87-232) Copyright Plenary Meeting, 27th, Topical Meetings on Life Sciences and From examining the consequences of not requiring that all Space Research XXlll(3): Natural and Artificial Ecosystems, Espoo, wastes from life support be recycled back to the food plants, it is Finland, July 18-29, 1988) Advances in Space Research (ISSN concluded that cellulose production on Mars could be an important 0273-1177), vol. 9, no. 8, 1989, p. 185-193. input for many nonmetabolic material requirements on Mars. The Copyright fiuxes of carbon in cellulose production would probably exceed The operation and evaluation of a bioreactor designed for high those in food production, and therefore settlements on Mars could intensity oxygen transfer in a microgravity environment is described. utilize cellulose farms in building a Mars infrastructure. Author The reactor itself consists of a zero headspace liquid phase separated from the air supply by a long length of silicone rubber A90-16533 tubing through which the oxygen diffuses in and the carbon dioxide A DIAGNOSTIC AND ENVIRONMENTAL MONITORING diffuses out. Mass transfer studies show that the oxygen is film SYSTEM (DEMS) CONCEPT TO SUPPORT MANNED MARS IN diffusion controlled both externally and internally to the tubing -FLIGHT AND SURFACE OPERATIONS and not by diffusion across the tube walls. Methods of upgrading CORINNE M. BUONI, MARK S. KOTUR, LARRY S. MILLER, and

60 54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT

BENJAMIN BARTILSON (Battelle Memorial Institute, Columbus, - Technical. San Diego, CA, Univelt, Inc., 1989, p. 217-223. refs OH) IN: The case for Mars 111: Strategies for exploration - (AAS PAPER 87-242) Copyright Technical. San Diego, CA, Univelt, Inc., 1989, p. 107-127. refs Physiology, physics and engineering set initial limits on space (AAS PAPER 87-234) Copyright habitats. Beyond these factors, anthropological, sociological and A microbiological assay concept for both in-flight and Martian aesthetic considerations become significant. Ideas on aesthetic surface application is discussed. The Diagnostic and Environmental use of space drawn from other cultures provide alternatives that Monitoring System (DEMS), which combines state-of-the-art could complement architectural and engineering concepts on colorimetric and immunoassay technology is proposed. The efficient use of space. Planned off-world communities can be advantages include the DEMS ability to conduct a large number viewed as the current incarnation of the architectural utopia of biological assay for a variety of samples (liquids, solids, and concept. An examination of two utopian cities built in the 50% atmosphere), eliminate time-consuming culturing techniques, Brasilia and Chandigarh, may provide valuable lessons to the provide a high degree of selectivity and sensitivity, respond rapidly, designers of orbital, lunar and Mars colonies. Both cities were meet the requirement for small size, and use commercially available intended to efficiently meet human needs, and are among the reagents and assay techniques. The advantages and disadvantages most interesting experiments in large-scale planned human habitats of current and improved microbiological diagnostic and monitoring available to us. Their successes and failures are of particular systems for a manned Mars mission are reviewed. The scientific relevance to planners of space habitats. Author basis of DEMS and the overall design and operational requirements are identified and discussed, including an engineering development strategy to create an initial version of DEMS available for Space Station applications. C.E. N90-12178'# Good Samaritan Hospital and Medical Center, Portland, OR. Dept. of Neuro-otology. AGE-RELATED CHANGES IN HUMAN POSTURE CONTROL: A90-16534 MOTOR COORDINATION TESTS A ZERO-G CELSS/RECREATION FACILITY FOR AN R. J. PETERKA and F. 0. BLACK 1989 13 p EARTHMARS CREW SHUTTLE (Contract NAGS-1 17) ALICE EICHOLD (California, University, Berkeley) IN: The case (NASA-CR-185855; NAS 1.26:185855) Avail: NTlS HC AO3/MF for Mars 111: Strategies for exploration - Technical. San Diego, CA, A01 CSCL 0518 Univelt, Inc., 1989, p. 129-138. refs Postural responses to support surface displacements were (AAS PAPER 87-235) Copyright measured in 214 normal human subjects ranging in age from 7 to This paper presents a zero-gravity architectural design for a 81 years. Motor tests measured leg muscle Electromyography module on an earth/Mars crew shuttle. Although in the early stages (EMG) latencies, body sway, and the amplitude and timing of of development and of uncertain immediate cost-effectiveness, changes in center of pressure displacements in response to sudden Controlled Ecological Life Support (CELSS) promises the most forward and backward horizontal translations of the support surface synergetic long-term means for providing food, air and water as upon which the subjects stood. There were small increases in well as accommodating 'homesickness'. In this project, plant growth both EMG latencies and the time to reach the peak amplitude of units have been combined with recreation facilities to ensure that center of pressure responses with increasing age. The amplitude humans have daily opportunities to view their gardens. Furthermore, of center of pressure responses showed little change with age if human exercise contributes toward powering the mechanical the amplitude measures were normalized by a factor related to systems for growing the plants. The solution was arrived at by subject height. In general, postural responses to sudden the traditional architectural design process with an empirical translations showed minimal changes with age, and all age related emphasis. The solution consists of smaller volumes for exercise trends which were identified were small relative to the variability facilities and plant growth units contained within a large geometrical within the population. Author sphere. Moisture and heat-generating activities thus share facilities and favorable gas exchanges are exploited. Author

N90-12179# Pennsylvania State Univ., University Park. Dept. A90-16539 of Engineering Science and Mechanics. INDIVIDUAL DIFFERENCES, MISSION PARAMETERS, AND WRIST ORIENTATION EFFECT ON GRIP STRENGTH AND SPACEFLIGHT ENVIRONMENT HABITABILITY ENDURANCE Final Report ALBERT A. HARRISON, NANCY J. STRUTHERS, and BERNARD JEAN LANDA PYTEL and THOMAS J. MACKIN 28 Nov. 1988 J. PUTZ (California, University, Davis) IN: The case for Mars 111: 25 P Strategies for exploration - Technical. San Diego, CA, Univelt, (Contract PHS-OH-02178) Inc., 1989, p. 191-199. refs (PB89-200935) Avail: NTlS HC AOSIMF A01 CSCL 0518 (AAS PAPER 87-240) Copyright The study provides basic data about some factors that may Preliminary results of empirical tests of a Three Factor Model affect the ability of an individual to apply a gripping force. The of environmental habitability are discussed. The impact of individual study determines the effect of wrist orientation on grip strength differences, environmental attributes and mission parameters on and grip endurance. Twenty men and 20 women were used as the rated acceptability of space habitat attributes is analyzed. The subjects. They were asked to apply a maximum static force to a individual differences include gender, age, occupational grip dynamometer and maintain a maximum contraction until their preferences, and preferred levels of activity. Environmental gripping force falls to 70 percent of the peak. The duration of the attributes include interior space availability, food and other grip force application was used as a measure of fatigue time or nutritional quality, availability of good hygiene facilities, and endurance. Peak forces and linear impulses (to determine how protection against radiation, bone decalcification, cardiac the gripping force changed) of the gripping forces at various wrist deconditioning, and other medical or health risks. Mission orientations were measured and related to the maximum values parameters such as mission destination and crew size are generated by each subject. Wrist orientations varied by 15-degree manipulated experimentally. Both individual differences and mission increments in wrist angle in four directions: plantar flexion, parameters affected rated acceptability. It is concluded that dorsiflexion, ulnar deviation and radial deviation. Relative changes spaceflight environment is considered equally acceptable for either in peak force, fatigue time and linear impulse were evaluated for a Mars or a moon base. C.E. all the subjects at all wrist positions and also compared between sex groups. This type of basic data is of use to those people who A90-16541 are concerned with musculoskeletal disorders. They will be able CONSIDERATIONS FOR THE LIVING AREAS WITHIN SPACE to suggest changes in the manner in which a tool is held in order SETTLEMENTS to decrease the susceptibility of an individual to musculoskeletal JOEL HAGEN IN: The case for Mars 111: Strategies for exploration disorders. GRA

61 ~~ -~

54 MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT

N90-12180# California Univ., Irvine. Dept. of Cognitive and incidents reported to the FAA, the rates by time of day were Sciences. calculated. Pilot age was also analyzed in relation to the time of DISCRIMINATING RIGID FROM NONRIGID MOTION Studies In day, phase of flight, and type of incident. B.G. the Cognltlve Sciences MYRON L. BRAUNSTEIN, DONALD D. HOFFMAN, and FRANK N90-13036*# Auburn Univ., AL. Dept. of Aerospace E. POLLICK 31 Jul. 1989 38 p Engineering. (Contract NO0014-88-K-0354; NO0014-87-G-0135; NSF PROPOSAL FOR A ZERO-GRAVITY TOILET FACILITY FOR BNS-88-19565; NSF lRl-87-00924; RR04209) THE SPACE STATION Final Report (ADA21 1794; UCI-51) Avail: NTlS HC A03/MF A01 CSCL EDGAR L. FLERI, JR., PAUL A. GALLIANO, MARK E. HARRISON, 0518 WILLIAM B. JOHNSON, and GREGORY J. MEYER Jun. 1989 Theoretical investigations of structure from motion have 56 p Sponsored by USRA demonstrated that an ideal observer can discriminate rigid from (Contract NASW-4435) nonrigid motion from two views of as few as four points. Three (NASA-CR-183151; NAS 1.26:183151) Avail: NTlS HC A04/MF experiments are reported that demonstrate similar abilities in human A01 CSCL 0611 1 observers: In one experiment 4 of 6 subjects made this This proposed toilet facility has a straightforward design. It discrimination from two views of four points; the remaining subjects has few moving parts and is easily maintained. Air and water flow required five points. Accuracy in discriminating rigid from nonrigid provide sanitary movement of the waste. The toilet's chambers motion depended on the amount of nonrigidity in the nonrigid are coated with Teflon which, along with the water flow, makes it structure. The measure on nonrigidity was based on the variance self-cleaning. An added disinfectant called Betadiene kills any of the interpoint distances over views. The ability to detect a rigid bacteria that may form on the chamber walls. The chair is contoured group dropped sharply as noise points (points not part of the rigid to take into account the neutral body position and the necessary group) were added to the display. It is concluded that human strain position for defecation. Restraints at the ankles, knees, and observers do extremely well in discriminating between nonrigid midsection hold the body in the chair. The waste is stored in and fully rigid motion, but do quite poorly at segregating points in discs of Gortex material which are inside a replaceable storage a display on the basis of rigidity. GRA chamber. This chamber can be removed, capped and stored until eventual return to earth. Author N90-12181# Naval Personnel Research and Development Center, San Diego, CA. N90-13037# Advanced Decision Systems, Mountain View, CA. THE EFFECT OF INCENTIVES ON THE RELIABILITY AND TELEROBOTIC CONTROL FOR TEAMS OF VALIDITY OF COGNITIVE SPEED TESTS Technical Report, FV SEMI-AUTONOMOUS AGENTS, PHASE 1 Final Report, 19 Jul. 1987 - FV 1988 1988 - 27 Feb. 1989 DENNIS P. SACCUZZO, GERALD E. LARSON, and JAMES MARCEL SCHOPPERS and DANIEL SHAPIRO 20 Apr. 1989 BROWN (San Diego State Univ., CA.) Jul. 1989 50 p 37 P (AD-A211346; NPRDC-TR-89-14) Avail: NTlS HC A031MF A01 (Contract DAAE07-88-C-R076) CSCL 0518 (AD-A211648; ADS-TR-3213-01) Avail: NTlS HC A03/MF A01 In the present study, financial incentives were used to motivate CSCL 23/2 test takers, so that the effect of motivation on elementary cognitive A Robotic Command Center is to be developed to allow a tests could be determined. One hundred and nine male and female commander and two drivers (three people) to control four remote volunteer college students were tested on a battery of vehicles. The drivers will be attempting to control two vehicles microcomputerized cognitive tests. One hundred of these subjects each, a difficult task. Giving vehicles a measure of autonomy is returned for a second session in which they were randomly one way to simplify that task. On the other hand, deployed vehicles assigned to an incentive or no incentive condition and then retested. must not be hampered by software with limited competence or The effort expended on the tests were measured via heart rate, reliability. The only solution available soon is a vehicle control skin conductance, and a self-report questionnaire pertaining to interface that allows for the entire range of possibilities between the perceived level of difficulty of the tests and amount of effort autonomous behavior and continuous teleoperation. Ideas are fused expended on them. Criterion measures, including the Advanced from telerobotics and from the Reaction Planning subfield of Otis-Lennon Test of Mental Abilities, Standard and Advanced Artificial Intelligence, to develop a technology that permits vehicles Raven Progressive Matrices, and scores on the Scholastic Aptitude to react autonomously to expected circumstances, while also Test were also taken. The findings revealed that incentives led to permitting the human operator to instruct vehicles about what to better performance only on the most complex task in the study. do and how to do it. This study will program some examples of In no case, however, did incentives affect the overall behaviors for the vehicles to perform semi-autonomously, and those IO-performance correlation for the tests used in the battery. These behaviors by running them in the Team Works I environment. An results support the view that correlations between cognitive speed interface was designed and built that allows the vehicle driver to and intelligence reflect common mental capacities, rather than communicate with the intelligent software controlling any and all some affective variable such as motivation. GRA of the vehicles. A single person is capable of controlling four simulated vehicles at the same time. The competence of the vehicle N90-13035'# Johns Hopkins Univ., Baltimore, MD. Injury is to be expanded to give the operator new ways of instructing Prevention Center. the vehicles, and to push those capabilities toward deployment in FATIGUE, PILOT DEVIATIONS AND TIME OF DAY Report, 15 the real world. GRA JuI. 1988 - 30 Jun. 1989 SUSAN P. BAKER 23 Jun. 1989 36 p N90-13038# Ecole Nationale Superieure des (Contract NCC2-555) Telecommunications, Paris (France). (NASA-CR-185369; NAS 1.26:185369) Avail: NTlS HC AO31MF STATE OF THE ART OF HUMAN/MACHINE DIALOG TOOL A01 CSCL 0518 PROTOTYPES [ETAT DE L'ART SUR LES OUTILS DE The relationshipsbetween pilot fatigue, pilot deviations, reported PROTOTYPAGE DE DIALOGUE HOMME-MACHINE] incidents, and time of day are examined. A sample of 200 Aviation FRANCOIS CORNEC Jun. 1989 66 p In FRENCH Safety Reporting System (ASRS) reports were analyzed from 1985 (TELECOM-PARIS-89-HOOl; ISSN-0751-1361; ETN-89-95505) and 200 reports from 1987, plus 100 reports from late 1987 and Avail: NTlS HC A04IMF A01 early 1988 that were selected because of possible association Computer madmachine interfaces available on the market are with fatigue. The FAA pilot deviation data and incident data were investigated and criticized. The need to develop interfaces with analyzed in relation to denominator data that summarized the hourly good graphic quality is stressed. The need for portable work operations (landings and takeoffs of scheduled flights) at major stations directed the researcher to use a bitmap screen, and use US. airports. Using as numerators FAA data on pilot deviations of a Macintosh was not excluded. The ideal tool is identified as

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one capable of operating on a wide variety of interface levels. Two active noise reduction systems for improving the sound The theory and function of different interface systems are attenuation of earmuffs are evaluated. The sound attenuation is outlined. ESA objectively and subjectively measured. The speech intelligibility of the intercom facility is measured in combination with noise. The N90-13039 Institute for Perception RVO-TNO, Soesterberg system increases the sound attenuation at frequencies below (Netherlands). Speech and Hearing Group. 500Hz up with 10 to 20 dB. The intelligibility in noise with a level PRE- AND POSTFLIGHT POSTURAL CONTROL OF THE D1 of 110 dB increases with 0.2 speech transmission index. A field SPACELAB MISSION ASTRONAUTS EXAMINED WITH A evaluation experiment revealed that the active noise reduction TILTING ROOM systems do not work at noise levels above 120 d6. Below this W. BLES and J. L. VANRAAIJ Dec. 1988 26 p level, most subjects preferred the active noise reduction systems (IZF-1988-25; TD89-0532; ETN-89-94462) Copyright Avail: to their earmuffs. ESA TNO Inst. for Perception, P.O. Box 23, 3769 ZG Soesterberg, Netherlands The postural stability of the astronauts, examined with N90-13043# Army Natick Research and Development Command, stabilometry in a tilting room, is examined. Postural control is MA. AIR FORCE FLIGHT FEEDING. VOLUME 1: EVALUATION OF effectuated again, on the preflight level, on the day after their CURRENT SYSTEM AND ALTERNATIVE CONCEPTS Flnal return from space. Two of the astronauts are examined a few Oct. 1982 Jan. 1985 hours after their spaceflight and their postural control is affected. Report, - ROBERT OBRIEN, BARBARA BELL, and CHRISTOPHER REES In one of them a preference for the visual information is found, Jul. 1989 157 p resulting in a large body sway and disturbed spatial orientation. The other astronaut preferred otolith information and maintained (Contract DAAK60-83-C-0055) (AD-A212789; NATlCK/TR-89/039-VOL-l) Avail: NTlS HC postural control with effort. Theoretical background, experimental AOB/MF A01 CSCL 06/8 set up and consequences are discussed. No correlation is found This report covers the initial phase of the project, during which between the behavior in the tilting room and spacesickness susceptibility. ESA the current Air Force flight feeding system was evaluated via an extensive data collection and analysis effort. Project objectives included development of a new flight feeding system concept to N90-13040# Laboratoire de Psychologie Experimentale, Grenoble meet the needs of current flight missions as well as those of the (France). coming decade, improved flight meal customer acceptance, and PSYCHOLOGICAL MECHANISMS INVOLVED IN THE increased operating efficiency of flight kitchens. Crew opinions DISORIENTATION OF PILOTS DUE TO FLIGHT CONDITIONS were obtained through 2,811 mail survey and 146 on-site surveys. Flnal Report [MECANISMES PSYCHOLOGIQUES IMPLIQUES Feedback was received on availability and acceptability of menu PAR LE PILOTAGE DES SYSTEMES DE POINTAGE] items, adequacy of galley equipment on board the aircraft, and CHRISTIAN MARENDAZ and THEOPHILE OHLMANN 1988 flight feeding issues in general. Project team members visited 20 p InFRENCH several Air Force bases to observe flight kitchens in operation, to (Contract DRET-86-047-00-470-75-01) collect technical data on selected aircraft, and to meet with key (ETN-89-95014) Avail: NTlS HC AO3/MF A01 personnel (crew members, food service personnel, aircraft A flight simulation apparatus designed to test the disorientation maintenance representatives) to determine current flight feeding effects of flight conditions is described. A pilot seat on a tri-axial deficiencies and to identify possible solutions. Structured telephone mounting with a variety of visual simulation accessories is surveys of 40 Air Force flight kitchens were conducted to determine described. Tests carried out to determine what type of movements equipment inventories, work space, storage space, and personnel cause flight motion sickness are described. Different visual illusions resources. GRA are used to test pilots ability to deal with situations in which there is no horizon line reference. The use of such a simulation bench to select individuals best suited for fighter pilot service or space flight is stressed. ESA 55 N90-13041 Institute for Perception RVO-TNO, Soesterberg (Netherlands). Human Performance Group. SPATIAL TESTS FOR AVIATORS SPACE BIOLOGY L. C. BOER Aug. 1988 24 p (Contract A85/K/077) Includes exobiology; planetary biology; and extraterrestrial life. (IZF-1988-15; TD88-4123 ETN-89-95090) Copyright Avail: TNO Inst. for Perception, P.O. Box 23, 3769 ZG Soesterberg, Netherlands A90-16035 The spatial ability measured by tests and required in the cockpit HOW DID THE FIRST CELLS APPEAR? [KAK POIAVILIS' of a fighter plane is discussed and new tests are proposed. They PERWE KLETKI?] are based on tasks occurring in the cockpit, and include aspects DAVID DEAMER (California, University, Davis), AL'FA 1. such as the conflict between cognition and sensation, and the MlKHAlLOV (AN SSSR, lnstitut Khimicheskoi Fiziki, Moscow, use of wide visual fields and moving objects. The spatial efficiency USSR), and SERGE1 A. SELEZNEV (Tselinogradskii Meditsinskii in the actual flying performance can be approximated by the use Institut, Tselinograd, Kazakh SSR) Priroda (ISSN 0032-874X), of checklists or rating scales for spatial performances in the air. Oct. 1989, p. 3-9. In Russian. refs Sense of direction, or navigation ability in real life are suggested Copyright as a secondary criterion. ESA The stage of chemical evolution preceding biological evolution is examined. An unorthodox scheme of biogenesis is proposed N90-13042 Institute for Perception RVO-TNO, Soesterberg with the following sequence of events preceding the appearance (Netherlands). Audiology Group. of the first organisms: (1) the appearance of primordial APPLICATION OF ACTIVE NOISE REDUCTION FOR HEARING membrane-separated cells made up of relatively simple molecules, PROTECTION AND SPEECH INTELLIGIBILITY IMPROVEMENT (2) the appearance of cells containing oligopeptides, and (3) the H. J. M. STEENEKEN and J. G. VANVELDEN Dec. 1988 24 p appearance of genetic material. In contrast to Oparin's model based (Contract A87/K/048) on the probability of the spontaneous appearance of protein (IZF-1988-21; TD89-0321; ETN-89-96005) Copyright Avail: aggregates, the present conception is based on the possibility of TNO Inst. for Perception, P.O. Box 23, 3769 ZG Soesterberg. the abiogenic synthesis of relatively simple lipidlike molecules Netherlands forming closed layered systems. B.J.

63 55 SPACE BIOLOGY

A90-16160' Chicago Univ., IL. PRE-BIOTIC ORGANIC MAlTER FROM COMETS AND ASTEROIDS EDWARD ANDERS (Chicago, University, IL) Nature (ISSN 0028-0836), vol. 342, Nov. 16, 1989, p. 255-257. Research supported by NASA. refs Copyright Only meteoritic fragments small enough to be gently decelerated by the atmosphere (10 to the -12th g to 10 to the -6th g) can deliver organic matter intact. The amount of such 'soft-landed' organic carbon can be estimated from data for the infall rate of meteoritic matter. At present rates, only about 0.0006 g/sq cm intact organic carbon would accumulate in 100 million years, but at the higher rates of about four billion yr ago, about 20 g/sq cm may have accumulated in the few hundred million years between the last cataclysmic impact and the beginning of life. It may have included some biologically important compounds that did not form by abiotic synthesis on earth. C.D.

A90-16360 3.5 BILLION YEARS AGO LIFE ON MARS? HINTS, ,I INDICATIONS, SPECULATIONS [VOR 3,5 MILLIARDEN JAHREN: LEBEN AUF DEffl MARS? HINWEISE, INDIZIEN, SPEKULATIONEN] JOHANNES FIEBAG (Karlstadt, Landratsamt, Federal Republic of Germany) Astronautik (ISSN 0004-6221), vol. 26, July-Sept. 1989, p. 81-83. In German. refs Copyright The geological aspects of Mars which bear on the possibility of life having existed there 3.5 Gyr ago are discussed. Cryptoendolithic organisms in Antarctica and algal mats in ice-covered seas are examined as examples of organisms that

I could survive under Martian conditions. The Elephant Moraine meteorite is considered as a possible evidence of extraterrestrial life. Evidence for the existence of extensive moisture on Mars in the distant past is discussed. C.D.

N90-12804'# Jet Propulsion Lab., California Inst. of Tech., Pasadena. THE NASA SET1 SKY SURVEY RECENT DEVELOPMENTS M. J. KLEIN, S. GULKIS, E. T. OLSEN, and N. A. RENZETTI ln its The Telecommunications and Data Acquisition Report p 21 8-226 15 Aug. 1989 Previously announced in IAA as A89-17852 Avail: NTlS HC A1 1/MF A02 CSCL 0613 NASA's Search for Extraterrestrial Intelligence (SETI) project utilizes two complementary search strategies: a sky survey and a targeted search. The SET1 team at the Jet Propulsion Laboratory (JPL) in Pasadena, California, has primary responsibility to develop and carry out the sky survey part. Described here is progress that I has been made developing the major elements of the survey including a 2-million channel wideband spectrum analyzer system that is being designed and constructed by JPL for the Deep Space Network (DSN). The system will be a multiuser instrument; it will serve as a prototype for the SET1 sky survey processor. This prototype system will be used to test the signal detection and observational strategies on DSN antennas in the near future. I Author

64 SUBJECT INDEX

AEROSPACE MEDICINE AND BIOLOGY /A Continuing Bibliography (Supplement 334) March 1990

ADAPTATION Age-related changes in human posture control: Motor Typical Subject Index Listing Plant cell in the process of the adaptation to simulated coordination tests microgravity p 25 A90-15054 [NASA-CR-185855] p61 N90-12178 USSR Space Life Sciences Digest. Issue 22 AIRCRAFT CARRIERS [NASA-CR-3922(26)-lSSUE-22] p 35 N90-12153 The effect of occupational work load on the functional USSR Space Life Sciences Dgest, ISSUB23 state of naval-aviation fliht personnel [NASA-CR3922(27)-ISSUE-23] p 36 N90-12154 p41 A90-14425 Studies on predicting the resynchronization of the AIRCRAFT MANEUVERS circadian system after transmedian Hiihts Influence of gravitoinertial force on vestibular nystagmus [DFVLR-FB-89-10] p48 N90-12172 in man observed in a centrifuge p 42 A90-15078 MASS FLOW ADAPTIVE CONTROL AIRCRAFT PILOTS A simple, mass balance model of carbon flow in a Adaptive information processing in auditory cortex Head cooling is desirable but not essential for preventing [ADA21 12941 p47 N90-12168 ecological life support system heat strain in pilots p57 A90-13737 (NASA-TM-102151] p 20 N90-10571 ADENOSINE DIPHOSPHATE Radoproteclive effects of ATP and ADP on The time required for U.S. Navy tighter pilots to shift T 77 membranebound enzymes p33 A90-15635 gaze and identity near and far targets r p41 A90-13740 ADENOSINE TRIPHOSPHATE Radioprotective effects of ATP and ADP on Recovery to + 1Gz and +2Gz following + Gz-induced membrane-bound enzymes p33 A90-15635 loss of consciousness - Operational considerations AEROSPACE ENGINEERING p41 AW-13741 Studies on Habitation Module and interconnecting Deep venous thrombosis in the military pilot elements for a future European space station p41 A90-1374% [IAF PAPER 894921 p55 A90-13305 The Occunence of the vection illusion among helicopter The subject heading is a key to the subject content AEROSPACE MEDICINE pilots while flying over water p 52 A90713743 of the document. The title is used to provide a Telescience testbed for pnysiological experiments Probable bends at 14,000 feet ~ A case report description of the subject matter. When the title is [ IAF PAPER 894341 p 37 A90-13267 p41 A90-13744 The basic health care system for the crew lunar base insufficiently descriptive of document content, a Galactic cosmic radiation exposure and associatej [IAF PAPER 89-5731 p38 A90-13612 health risks for air canier crewmembers title extension is added, separated from the title Medical results of the flight of the second prime crew p41 A90-13745 the wbital station Mir by three hyphens. The (NASA or AIAA) accession on The spousal factor in pilot stress p 52 A90-13747 [ IAF PAPER 89.5941 p 38 A90-13626 number and the page number are included in each A comparison of two subject-controlled attitude orthostatic intolerance post space flight A multifactwial entry to assist the user in locating the abstract in - measures during somatogravic illusion exposure [ AD-Ml25281 p53 N90-13031 the abstract section. If applicable, a report number [IAF PAPER 89-5951 p 39 A90-13627 is also included as an aid in identifying the docu- AIRCRAFT SAFETY NASA spinoffs to bioengineering and medicine A comparison of two subjectcontrolled attitude ment. Under any one subject heading, the acces- [IAF PAPER 89-6831 p 40 A90-13673 measures during somatogravic illusion exposure sion numbers are arranged in sequence with the Deep venous thrombosis in the military pilot [AD-A212528] p 53 N90-13031 p 41 A90-13742 AIAA accession numbers appearing first. ALANINE Occupational injuries sulfered by fkght attendants while Boron analogues of amino acids and derivatives on board p41 A90-13746 [AD421131 11 p36 N90-12157 International Union of Physiological Sciences ALGAE A Commission on Gravitational Physiology, Annual Meeting. Application of tubular photo-boreactorsystem to culture 10th. Montreal, Canada, Oct. 9-14. 1988. Proceedings spirulina for gas exchange and food production in p42 A90-15477 CELSS Pre-biotii organic matter from comets and asteroids The Life Sciences programat the NASA Ames Research [IAF PAPER 89-5771 p56 A90-13616 p64 A90-16160 Canter - An overview p 30 A90-15478 Closed and continuous algae cultivation system for food Space Station accommodationof liesciences in support production and gas exchange in CELSS ACCELERATION STRESSES (PHYSIOLOGY) of a manned Mars mission Hom~~laland cardiovascularchangesduring lower body p 60 A90-15445 negative and positive pressures [AAS PAPER 87-2331 p35 A90-16532 ALTITUDE SIMULATION [IAF PAPER 89-6001 p39 A90-13632 A diagnostic and environmental monitoring system Reduced systolic blood pressure elevations during (DEMS) concept to support manned Mars in -flight and maximum exercise at simulated altitudes Recovery to +lGz and +2Gz following +Gz-induced surlace operations p 40 A90-13738 loss of consciousness - Operational considerations [AAS PAPER 87-2341 p60 A90-16533 p41 A90-13741 AMINO ACIDS Work on human adaptation to long-term space flight in Boron analogues of amino acids and derivatives Dorsal light response and changes of its responses the UK LAD-AZ113111 p36 N90-12157 under varying acceleration conditions - in goldfish [AAS PAPER 87-2371 p 46 A90-18536 AMPHIBIA p 28 Am-15080 Astronaut interdisciplinary and medicalldental training The amphibian egg as a model system for analyzing Periodic acceleration stimulation in a weightlessness for manned Mars missions gravity effects p28 A90-15074 environment (PASWE) - A new science? [AAS PAPER 87-2381 p46 A90-18537 AMPLIFICATION p30 A90-15479 Space physiology and medicine (2nd edition) --Book Base level management of rad0 frequency radiation InterserOSal pressures and circulatory homeostasis p 46 A90-16625 protection program during changes in the gravitational inertial force USSR Space Life Sciences Digest, Issue 24 [ADA2117871 p48 N90-12171 environment p42 A90-15480 [NASA-CR-3s22(28)-lssUE-24] p 35 N90-12152 ANAEROBES Effect of inaeased acceleration on lung expansion in USSR Space Life sdences Digest, Issue 22 Evidence for anoxygenic photosynthesis from the dogs - Prone M. supine body positions [NASA-CR-3922(26)-ISSUE-22] p 35 N90-12153 distribution of bacteriochlorophylls in the Black Sea p33 A90-15500 USSR Space Life Sciences Digest, Issue 23 p24 A90-14831 ANGULAR ACCELERATION ACOUSTIC ATENUATION [NASA-CR-3922(27)-lSSUE-23] p 36 N90-12154 Influence of gravitoinerlial force on vestibular nystagmus Application actiwe noise reduction for hearing of Aerospace medicine and biology: A continuing in man observed in a centrifuge p 42 A90-15078 protection and speech lntelliiibilii improvement bibliography with indexes (supplement 329) ANOXIA [ IZF-198821] p63 N90-13042 [NASA-SP-7011(329)] p 48 N90-12173 Synergisticeffects of nitrogen dioxide and carbon dox& ACOUSTOOPTlCS Biochemical and phy$ological changes in gliir pilots following acute inhalation exposures in rats Sound Localkation by Human Observers symposium during multihour flights [PB89-214779] p35 N90-12150 proceedings [ DLR-FB-89-291 p49 N90-13018 ANTIDIURETICS [ADA2128771 p51 N90-13026 AEROSPACE TECHNOLOGY TRANSFER Changes in kidney response to ADH under hypogravity ACTIVATION NASA spinoffs to bioengineering and medicine - Rat models and possible mechanisms Synaptic pl&kiiy and memory formation [IAF PAPER 89-6831 p40 Am-13673 p 30 A90-15482 [ADA2113681 p36 N90-12158 AGE FACTOR ANTIOXIDANTS ACTIVE CONTROL Work capacity, exercise responses and body Skeletal muscle antioxidant enzyme levels in rats atter Active vibration control for flexible space environment compositbn of professional pilots in relation to age simulated weightlessness. exercise and dobutamine use manipulators p60 A90-16522 p40 A90-13739 p 32 A90-15498 ANTISEPTICS SUBJECT INDEX

ANTISEPTICS BARRIERS Otoliih-spinal reflex testing on Spacelab-1 and 0-1 Effect of iodine disinfection products on higher plants The dent research animal holding facility as a barrier p 43 A90-15495 p 29 A90-15438 to environmental contamination Continuing studiis of 'CELLS fliht hardware ANXIETY [NASA-TM-102237] p35 N90-12151 p 32 A90-15497 Fear-potentiatedstartle as a model system for analyang BED REST Carotid baroreflex response following 30 days exposure learning and memory Effect on the dicfunction of repeated LBNP during to simulated microgravity p 44 A90-15502 [ADA2121311 p53 N90-13029 a one month head down tilt Central venous pressure in humans during short periods AORTA [IAF PAPER 89-5931 p38 A90-13625 of weightlessness p44 A90-15504 Regional aortic pressure apparent phase velocity in the Changes of muscle function and size with bedrest Wiorespiratwy responses to simulated baboon during 70 degree tilt p44 A90-15507 p43 A90-15501 weightlessness in man p44 A90-15505 ARTIFICIAL INTELLIQENCE Hemodynamics of leg veins during a 30 days bed rest Gravitational influence on systemic arterial dynamics Three dimensional objecl recognition employing - Effect of lower body negative pressum (LBNP) using a B-element Windkesael model p 44 A90-15506 combined visual and tade sensing p45 A90-15508 Regional aortic pressure apparent phase velocity in the [PBEW194891 p52 NW-12176 Difference in diascular responses to blood pooling baboon during 70 degree tilt p 44 A90-15507 Telerobotic control for teams of semi-autonomous patterns between LBNP and head up tiHing stimulated after Hemodynamics of leg veins during a 30 days bed rest agents. phase 1 supine cycling in wmn p45 A90-15509 - Effect of merbody negative pressure (LBNP) [ADA21 16481 p62 N90-13037 BIBLIOGRAPHIES p 45 A90-15508 ASTEROIDS Aerospace medicine and biology: A continuing Pilot performance is increased after alternating hypo- prebiotic organic matter from comets and asternids bibliiraphy with indexes (supplement 329) and hypergravity states p45 A90-15511 . p64 A90-16160 [NASASP-7011(329)1 p48 N90-12173 Siinlficance of liiht and social CUBS in the maintenance ASTRONAUT PERFORMANCE BINAURAL HEARING of temporal organization in man p 45 A90-15512 Human factors and productivity on Space Station Binaural masking: An analysis of models Exercise strategies and assessment of cardiorespiratory Freedom [ADA2115781 p48 N90-12168 finess in space [IAF PAPER 89-0871 p55 A90-13301 BINOCUUR VISION [AAS PAPER 87-2361 p46 ASO-16535 Psycho-physiologml studii during the fight of the Binocular depth perception and its hyperacuity in Work on human adaptation to long-term space flight in second Bulgarian cosmonaut common and spedally selected subjects the UK [IAF PAPER 89-5861 p38 A90-13621 [IAF PAPER 89-5881 p 38 A90-13622 [AAS PAPER 87-2371 p 46 A90-16536 Binocular depth perception and its hyperacuity in The time required for U.S. Navy Qhter pilots to shift Automation of fitness management for extended space common and specially selected subjects gaze and identify near and far targets missions [IAF PAPER 89-5881 p36 A90-13622 p41 A90-13740 [AAS PAPER 87-2391 p 46 A90-16538 Pilot performance is increased after alternating hypo- BIOASTRONAUTICS Aerospace medicine and biology: A continuing and hypergravity states p45 A90-15511 Bornediil payload of the FrenchSoviet long duration bibliography with indexes (supplement 329) Significance of light and social cues in the maintenance flight - First conclusions [NASA-SP-7011(329)] p48 N90-12173 of temporal organization in man p 45 A90-15512 [IAF PAPER 89-5631 p37 A90-13606 BIOCHEMISTRY Robotics and telmperation p60 A90-16352 Effect of space fliih!s and hypokinesia on plasma insulin A report of ground results for brain function experiments Pre- and postflight postural control of the D1 Spacelab levels and insulin receptors in rat liver in space mission astronauts examined with a tilting room [IAF PAPER 89-5641 p23 A90-13607 [IAF PAPER 89-5903 p38 A90-13624 [ IZF-1988-251 p63 N90-13039 Long-term exposure to zerc-g and the gastro-intestinal Biochemical correlates of neurosensory changes in ASTRONAUT TRAINING tract function wetghtlessness Space Station Freedom crew training [IAF PAPER 89-5691 p37 A90-13610 [IAF PAPER 89-5981 p 30 A90-13630 [ IAF PAPER 89-0981 p51 Am-13308 me basic heaith care system for me mew lunar base Astronaut interdisciplinary and medicalldental training [IAF PAPER 89-5731 p38 A90-13612 Biochemical and histochemical ObWNatiOnS of VaStuS for manned Mars mias'ons A report of ground results for brain function experiments medialis from rats nown in Cosmos 1887 (experiment [US PAPER 67-2381 p46 A90-16537 in space K608) p31 AM-15484 ATROPHY [IAF PAPER 89-5901 p38 A90-13624 Neurochemistry of hibernation in mammals --.Russian Modifications of bone atrophy seen with hindlimb Medical results of the flight of the second prime crew book p 34 A90-16057 suspension by exercise and dobutamine on the olbital station Mir Synaptic plasticii and memory formation p31 A90-15487 [IAF PAPER 89-5941 p 38 A90-13626 [AD-A211368] p36 N90-12158 ATTENTION Orthostatic intolerance wst.. mace flight - - A multifactorial Cellular and molecular mechanisms of high pressure Elechophysiological studies of visual attention and disordeR inotropy in cardiac muscle resource allocation [IAF PAPER 89-5951 p39 AM-13627 [APA2116951 p4.9 NSO-12170 [ADA2122871 p53 N90-13030 Effects of body posture on the interpretation of Fear-potentiatedstartle as a model system for analyzing ATTITUDE (INCLINATION) biomedical data obtained from manned missions learning and memory Regional ao& pressure apparent phase veWi in the [IAF PAPER 89-5961 p 39 A90-13628 [AD-A2121311 p53 N90-13029 baboon during 70 degree tilt p44 A90-15507 Biochemical conelates of neurosensory changes in BIOCONTROL SYSTEMS weightlessness A comparison of two subjectcontrolled attitude A Scheiner-principle pocket optometer for [IAF PAPER 89-5961 p39 A90-13630 self-evaluation and biofeedback accommodation training measures during somatogravic illusion exposure Fluid distribution pattern induced by intravenous fluid [ AD-AZl 25261 p53 NW-13031 [ADA2131711 p51 N90-13027 loading during HDT BIOCONVERSION AUDITORY PERCEPTION [IAF PAPER 89-5991 p39 A90-13631 Design for a bioreacior with sunlight supply and Binaural masking: An analysis of models Hormonaland cardiovascular changes during lower body [ADA2115781 p48 N90-12168 opetations systems for use in me space environment negative and positive pressures p59 A90-15444 Time-frequency factors in auditory perceptbn [IAF PAPER 896001 p 39 A90-13632 [ADA2114911 p49 N90-13016 Experimental research on the applicabilities of Chinese BIODEGRADATION Shape instabilities of plate-like structures. 1: medicine to space medicine Synaptic plasticity and memory formation Eqzeimental observations in heavily cold worked in situ [IAF PAPER 894011 p 39 A90-13633 [ADA2113681 p36 N90-12158 composites Study of activation of human peripheral blood BIODYNAMICS [AD-A212251] p 50 N90-13021 mononuclear cells after a space flight Dependence of the amplitude of kinesthetic evoked AUDITORY SIGNALS [IAF PAPER 89611 I p24 A90-13639 potentials on the velocity and acceleratjon of the motion Binaural masking: An analysis of rodels Life Scienoes and space research XXlIl(5) - Gravitatjonal of a monkey's hand p24 A90-14446 [AD-A211578] p48 N90-12168 biology; Proceedings of the Top~cal Meeting and BIOELECTRIC POTENTIAL Xmefrequency factors in audiory perception Works- XVll and XVlll of the 27th COSPAR Plenary Electrophysiological studies of visual attention and [ADA211491 I p49 N90-13016 Meeting. Espoo, Finland, July 18-29.lSSe resource allocation [ADA2122871 p53 N90-13030 AUDITORY STIMUU p25 A90-15051 Sound Localmtion by Human ObseNWS symposium Developmental biology in space - Why and how7 BIOENGINEERING proceedings p27 A90-15070 NASA spinoffs to bioengineering and mediiine [ADA2128771 p51 N90-13026 Insects as test systems for assessing the potenW role [IAF PAPER 698831 p 40 A90-13673 of microgravity in biological development and evolution AUTOMATIC CONTROL BIOFEEDBACK p27 A90-15071 Computer generation of a Moria1 dialogue The CZ3A - First step to a monitwing system of GELS Fertilization of frog eggs on a sounding rocket in in fliht p 59 A90-15437 [ADA21 19761 p46 N90-12162 space p 28 A90-15076 A Scheiner-principle pocket optometer for Early development in the mouse - Would it be affected self-evaluation and biofeedback accommodation training by "'"era? p28 A90-15077 [ADA2131711 p51 N90-13027 B The biological clock of Neurospora in a microgravity BIOLOGICAL EFFECTS environment p29 A90-15082 BACKGROUND NOISE The expression of a circadian rhythm in two strains of Advances in combustion toxicology. Volumes 1 8 2 - Book p24 A90-13903 Binaural masking: An analysis Of models Chlamydomonas reinhardii in space p 29 A90-15083 [ADA2115781 p48 N90-12168 Rhythmic ~IO@Wsystems under micrc-g condiis Accumulation of the biological effects of microwaves BACTERIA p 29 A90-15084 as displayed in the behavior, the physical efficiency. the Evidence for anoxygenic photosynthesis from the Gravitational biology and the mammalian circadian body-mass increase, and the condition of cerebral disttbutjon of bacteriochlorophylls in the Black Sea timing system p29 A90-15085 neurons p33 A90-15637 p24 A90-14631 Miogravity-induced changes in human bone strength Aerospace rnediiine and biology: A continuing Cerbon cycling by cellulosefermenting nitrogen-fixing p43 A90-15493 bibliography with indexes (supplement 329) bacteria p30 A90-15442 Studii of space adaptation syndrome in experiments [NASA-SP-701l(329)I p48 N90-12173 Genetic engineering of enhanced microbial nMication on primates performed on board of Soviet biosatellite BIOLOGICAL EVOLUTION [P889-208334] p36 N90-12155 'Ceamos-1887' p32 A90-15494 How did the first cells appea17 p 63 A90-16035

A-2 SUBJECT INDEX CLINICAL MEDICINE

BIOLOGICAL MODELS (MATHEMATICS) BORON Heatstroke pathophysiology: The energy depletion Predicting the postradiative radiosensitivity of mammals Boron analogues of amino acids and derivatives model and man according to the LD50 criterion after acute [ADA2113111 p36 N90-12157 [ADA2121561 p47 N90-12164 external irradiation p34 A90-15639 BOXES (CONTAINERS) Cardiovascular, renal. electrolyte, and homnal WOLOGY The rodent research animal holding facility as a barrier changes in man during gravitational stress, Life sciences and apace research XXlIl(5) - Gravitational to environmental contamination weightlessness, and simulated weightlessness: Lower biology; Proceedings of the Topical Meeting and [NASA-TM-102237] p35 N90-12151 body positive pressure applied by the antigravity suit Workshops XVll and XVlll of the 27th COSPAR Plenary BRAIN [ NASA-TM-1022321 p49 N90-13013 Meeting. Espoo. Finland, July 1829.1988 A repwt of ground results for brain function experiments CAROTID SINUS REFLEX p25 A9015051 in space Carotid baroreflex response following 30 days erposure BIOREACTORS [IAF PAPER 89-5901 p 38 A90-13624 to simulated microgravity p44 A90-15502 Thin film bioreactors in space p 27 A90-15068 Accumulation of MoIogical effects microwaves the of CARRIER FREWENCIES as displayed in the behavior, the physical effidency. Design for a bioreaclor with sunlight supply and the Time-frequency factors in auditoly perception operations systems for use in apace environment body-mass increase, and the condition of cerebral the [ADA2114911 p49 N90-13016 p 59 A9015444 neurons p33 A90-15637 Phase separated membrane bioreactor - Results from Effect of Wing radiation on the binding of muscimol CASUALTIES model system studii p60 A9015447 by synaptic membranes of the rat brain Prediction of thermal stress casuaks BIOSYNTHESIS p 34 A90-15640 [ADA2123561 p 50 N90-13022 Memkane fusion: The role of polyphosphatkjylinositol Effect of ultrahighdose ionizing radiation on the content CATECHOIAMINE [AD42112891 p36 N90-12156 of cathecholamine mediitors in various regions of the rat Effect of ultrahighdose ioniing radiation on the content BIOTECHNOLOGY brain p34 A90-15641 of cathecholamine mediitors in various regions of the rat Innovative approaches to the design of Moregenerative Neurochemisby of hibemation in mammals --- Russian brain p34 A90-15841 life suppod systems for advanced missions book p34 A90-16057 CELL MEMBRANES (BIOLOGY) [IAF PAPER 894261 p54 A90-13261 BRYOPHYTES Gravity and the membrane-solution interface . BLOOD CELLS Long dimtation influence on the localkation of free Theoretical investigations p 28 A90-15050 Study of activation of human peripheral blood and weaklv bound calcium in cell walls of Funaria Plant cell plasma membrane structure and properties mononuclear cells after a space right hygrometriia moss protonema cells p 27 A90-t 5064 under clinostatling p26 A90-15061 [IAF PAPER 89-61 t ] p24 A90-13639 BUBBLES Long clinostation influence on the localization of frea BLOOD ClRCULAnON Gas bubble descence in reduced gravity conditions and weakly bound calcium in cell walls of Funaria Plasma ANF concentrations during head-down bed rest p30 A90-15446 hygrometrica moss protonema cells p 27 A90-15064 of various duration (from several hours to one month) - How did the first cells appear? p 63 A90-16035 Role of LBNP countermeasure p 44 A9015503 CELLS (BIOLOGY) Gravitational influence on systemic arterial dynamics C Importance of the 1g controls in interpteting the results using a 3-element Windkessel model p 44 A90-15506 CAFFEINE of an experiment on plant gravitropism (Biorack, D'I BLOOD PLASMA mission) Effect of space flights and hypokinesia on plasma insulin The effect of caffeine on endurance time to exhaustion at high altitude [IAF PAPER 89-6091 p 24 A90-13637 levels and insulin receptors in rat liver Plant cell in the process of the adaptation to simulated [IAF PAPER 89-5641 p 23 A90-13607 [ADA21 20691 p47 N90-12163 CALCIUM microgravity p 25 A90-15054 Plasma stress hormones in resting rats ~ Eighty four Calcium gradient in plant cells with polarized growth in Normalisation of bone cellular responses occurs day study p32 A90-15489 between 7 and 14 days of simulated weightlessness in simulated microgravity p 26 A90-15056 Plasma ANF concentrations during headdown bed rest rats p31 A90-15486 of various duration (from several hours to one month) - Long clinostation influence on the localization of free and weakly bound calcium in cell walls of Funaria Heatstroke pathophysiology: The energy depletioli Role of LBNP countermeasure p 44 AM-15503 model BLOOD PRESSURE hygrometrica moss protonema cells p 27 AM-15064 lnvesbgation of resonant acdc magnetic field effects [ ADA2121 561 p 47 N90-12161 lnterserosal pressures and circulatory homeostasis CELLULOSE [ADA21 16121 p37 N90-12159 during changes in the gravitational inertial force Utilization of white potatoes in CELSS environment p42 A90-15480 Calcium displacement caused by electromagnetic fields p5E A90-15431 Responses to changed perfusion pressure in working Carbon cycling by cellulose-fermenting nitrogen-fixing [ADA2126901 p N90-13023 muscles - Factors to be considered in exercise testing in 50 bacteria p30 A90-15442 space flights? p42 A90-15481 CALCIUM METABOLISM Calcium homeostasis in prolonged hypokinesia The case for cellulose production on Mars Carotid baroreflex response following 30 days exposure [AAS PAPER 87-2321 p 43 A90-15492 p60 A90-16531 to simulated microgravity p44 AM-15502 CENTRIFUGAL FORCE CARBOHYDRATE METABOLISM Central vemspressure in humans during short periods Geotropic sensitivity of hornets p 27 A90-15072 of weightlessness p 44 A90-15504 Heatstroke pathophysiology: The energy depletion model Influence of gravitoinertial force on vestibular nystagmus Regional aortic pressure apparent phase velocity in the in man ObSeNed in a centrifuge p 42 AM-15076 [ADA2121 561 p47 N90-12164 baboon during 70 degree tilt p44 A90-15507 CEREBRALCORTEX BLOOD VOLUME CARBON CYCLE Evidence for anoxygenic photosynthesis from the Adaptive information processing in auditory cortex Increasing central Mood volume with head-down tilting [AD-A211294] distribulbn of bacteriochlorophylls in the Black p47 N90-12166 would inhibit water intake during mild pedaling at 25 C Sea CHEMICAL EVOLUTION and 35 C room temperatures in woman p24 A90-14631 Carbon balance and productivity of Lemna gibba. a How did the first cells appean p 63 A90-16035 p45 A90-15510 CHLORELU candiite plant for CELSS p 58 A90-15430 BODY COMPOSlTlON (BIOLOGY) Ultrastructural and growth indices of Chlorella culture C&n cycling by cellulose-fermenting nitrogen-fixing Work capacity. exercise responses and body in multicomponent aquatic systems under space flight composition of professional pilots in relation to age bacteria p 30 A90-15442 conditions p27 A90-15083 p 40 A90-13739 CARBON DIOXIDE Synergistic effects of nitrogen dioxide and carbon dioxide CHLOROPHYLLS Long dimtation influence on the localization of free Evidence for anoxygenic photosynthesis from the following acute inhalation exposures in rats and weakly bound calcium in cell walls of Funaria distribution of bacteriochlorwhylls in the Black Sea hygromeeica moss protonema calls p 27 Am-15064 [PB89-214779] p35 N90-12150 Effects of atmosphecic mk and toxic fumes on mili p24 A90-14831 BODY FLUIDS CIRCADIAN RHYTHMS performance USSR Spece Life sdences Digest, Issue 22 Changes in circadian rhythm of multiple hormones and [NASA-CR-3922(26)-lSSUE-22] p 35 N90-12153 [PB89-223630] p49 NQO-13015 CARBON DIOXIDE CONCENTRATION their relationship with individual susceptibility in simulated BODY TEMPERATURE weightlessness Temperature regulation in rats exposed to a 2 G field Effect of C02 and 02on development and fnrctification of wheat in closed systems p 57 A90-15428 [IAF PAPER 89-5651 p37 A90-13608 p32 A90-15499 The biologiil clock of Neurospora in a microgravity Human body regional convective heat transfer The case for cellulose production on Mars [AAS PAPER 67-2321 p60 A90-16531 environment p 29 A90-150R2 determination using sublimating naphthalene disks The expression of a circadian rhythm in two strains of [ADA2121701 p47 N90-12165 CARBON MONOXIDE Effec(s of atmospheric mix and toxic fumes on milby Chlamydomonas reinhardii in space p 29 A90-15083 PrediiOf thermal stress CBsUBlties Rhythmic biobgil systems under micro-g conditions perf-- [ADA2123561 p 50 N90-13022 p 29 A90-15084 Radio frequency (13.56 MHz) energy enhances [P889-2223830] p49 NQO-13015 CARDIOVASCULAR SYSTEM Gravitational biology and the mammalian circadian rewarming from mild hypothermia timing system p 29 A90-15085 [ADA2127031 p50 N90-13024 Honnonalandcardiiascularchangegduringlowerbody negative and poaiwve pessures Studies on predicting the resynchronization of the BONE DEMINERALIZATION circadian system after transmediin flights Microgravity-induced changes in human bone strength [IAF PAPER 89-8001 p39 A8013632 Cardiorespiratory responses to simulated [ DFVLR-FB-89-101 p48 N90-12172 p 43 A9015493 Effectsof a time zone shift of nine hours on the circadim weightkameas in man p 44 A90-15505 Immunocompetent calls produdng humoral mediators rhylhms in cockpit aircrew members on longhaul flights of bone tissue mineral metabolism during space right Difference in cardiovastularresponses to Mood pooling patterns between LBNP head up tilting stimulated after [DLR-FB-89-31] p 49 N90-130'19 simulation p43 A90-15496 and CIRCULATORY SYSTEM supine cycling in women p45 A90-15509 Life beyond gravity P45 A90-16299 Propranololand the compensatory circulatory responses Exercise strategies and assessment of cnrdiorespiratoly BONES to orthostasis at high altitude p40 A90-13736 Normalisation of bone cellular responses OCCUR fitness in space CLINICAL MEDICINE between 7 and 14 days of simulated weightlessness in [AAS PAPER 87-2361 p46 A90-16535 The basic health care system for the crew lunar base rats p31 A90-15486 USSR Space Life Sciences west. Issue 22 [IAF PAPER 89-5731 p38 A90-13612 Modifications of bone atrophy seen with hindlimb [NASACR3922(26)-lSSUE-221 p 35 N90-12153 Astronaut interdisciplinary and mediilldental training suspension by exercise and dobutem,'ne USSR Space Life Sciences Dtgest. Issue 23 for manned Mars missions p31 A90-15487 [NASACR-3922(27)-ISSUE-231 P 36 N90-12154 [AAS PAPER 87-2381 p46 A90-16537

A-3 CLOSED ECOLOGICAL SYSTEMS SUBJECT INDEX

CLOSED ECOLOGICAL SYSTEMS COMBUSnON CHEMISTRY CONTRACTION Innovative approaches to the design of bioregenerative Advances in combustion toxicology. Volumes 1 8 2 - The effect of concurrent strength and endurance training lie support systems for advanced missions Book p 24 A90-13903 on el&omechanical delay, maximum voluntary [IAF PAPER 89-0261 p54 A90-13261 contraction, and rate of force development COMBUSTION PRODUCTS p51 N90-13028 Study on the nilmgen fixation system required for plant Advances in combustion todcology. Volumes 1 8 2 --- [AD42133161 culture in a lunar base Book p 24 A90-13903 CONTROL SYSTEMS DESIGN [IAF PAPER 895751 p56 A90-13614 Desgn and evaluation of man-in-the-loop control system COMETS A study on culturing modules for CELSS in lunar base of Japanese Experimental Module Remote Manipulator Pre-biotic organic matter from comets and asteroids System [IAF PAPER 89-5761 p56 A90-13615 p64 A90-16160 Application of tubular photwbioreactor system to culhrre [IAF PAPER 890901 p55 A90-13303 spirulina for gas exchange and food production in COMMAND AND CONTROL CONVECTIVE HEAT TRANSFER CELSS Telerobotic control for teams of semi-autonOmOUs Human body regional convective heat transfer [IAF PAPER 895771 p56 A90-13616 agents. phase 1 determination using sublimating naphthalene disks p47 N90-12165 A food/nutrient supply plan for lunar base CELSS [ADA2116481 p62 N90-13037 [ADA2121701 [IAF PAPER 89-5791 p56 A90-13618 COMMERCIAL AIRCRAFT Prediction of thermal stress casualties Plant cultural system incocpwated into CELSS The spousal factor in pilot stress p 52 A90-13747 [ADA2123561 p 50 N90-13022 CObLlNG [ IAF PAPER 89-5601 p 57 A90-13619 COMMUNITIES Ultrasbuctwal and grhindices of Chlorella culture Head woling is desirable but not essential for preventing Gmsi&rations for the ling areas within space heat strain in pilots p57 A90-13737 in multicomponent aquatic systems under space flight settlements conditions p27 A90-15063 COSMIC RAYS [AAS PAPER 87-2421 p61 A90-16541 Galactic cosmic radiation exposure and associated Life sciences and space research XXlll(3): Natural and COMPUTER AIDED DESIGN artifkkl ecosystems; Proceedingsof the Topical Meetings health risks for air canier crewmembets Simulation by personal workstation for Man-Machine p 41 ASO-13745 of the 27th COSPAR Plenary Meeting, Espoo, Finland, Interface design Biophysical pcinciples of the effects of cosmic rays and July 18-29, 1- p 57 A90-15426 [IAF PAPER 890891 p 55 A90-13302 Current and potential productivity of wheat for a radiation from accelerators _-- Russian book. COMPUTER ASSISTED INSTRUCTION p 34 A90-16047 controlled environment lie support system p 57 A90-15427 Computer generation of a tutorial dialogue COUNTERMEASURES [ADA2119761 p46 N90-12162 Effect of CO2 and 02 on development and fructification Hemodynamics during head down tilting and lower body of wheat in closed systems p 57 A90-15428 COMPUTER GRAPHICS negative pressure and pharmacological interventions for Utiliition of sweet potatoes in controlled ecological lie Using computer graphics to design Space Station countermeasures support systems (CELSS) p58 A90-15429 Freedom viewing [IAF PAPER 89-5971 p 39 A90-13629 Carbon balance and productivity of Lemna gibba, a [IAF PAPER 89-0931 p56 A90-13306 CREWS candidate plant for CELSS p 58 A90-15430 COMPUTER PROGRAMS Air Force flight feeding. Volume 1: Evaluation of Current Transpiration during life cycle in controlled wheat The effect of concurrent strength and endurancetraining system and alternative concepts growth p58 A90-15432 on electromechanical delay, maximum voluntary [AD-A212789] p63 N90-13043 Long-term experiments on man's stay in biological contraction, and rate of force development CROP GROWTH life-support system p 58 A90-15433 [ADA21 33161 p51 N90-13028 Study on the nitrogen fixation system required for plant Waste recycling iwsin bioregenerative lie support COMPUTER SYSTEMS DESIGN culture in a lunar base p 59 A90-15434 State of the ad of humanlmachine dialog tool [IAF PAPER 89-5751 p56 A90-13614 Sources and processing of CELSS wastes prototypes Plant cultural system incorporated into CELSS p 59 A90-15435 [TELECOM-PARIS-89-HOlJ p62 N90-13038 [IAF PAPER 89-5801 p 57 A90-13619 Subcritical and supercritical water oxidation of CELSS COMPUTER TECHNIQUES Evaluation of experiments involving the study of plant model wastes p 59 A90-15436 Computer generation of a tutorial dialogue orientation and growth under different gravitational The C23A - First step to a monitwing system of CELSS [ADA2119761 p46 N90-12162 conditions p25 A90-15053 in flight p 59 ASO-15437 COMPUTER VISION Current and potential productivity of wheat for a Effect of iodine disinfection products on higher plants Three dimensional object recognition employing controlled environment lie support system p 29 A90-15438 combined visual and tactile sensing p 57 A90-15427 Productivity and food value of Amaranthus cruentus [PB89-219489] p52 N90-12176 Effect of CO2 and 02 on development and fructification under non-lethal salt stress p30 A90-15440 COMPUTERIZED SIMULATION of wheat in closed systems p57 A90-15428 Design for a bioreactor with sunlight supply and The role of computerized modeling and simulation in Transpiration during life cycle in controlled wheat operations systems for use in the space environment the development of lie support system technologies growth p58 A90-15432 p59 A90-15444 p 59 ASO-15439 Closed and continuous algae cultivation system for food CRYSTAL GROWTH Telerobotic control for teams of semi-autonomous production and gas exchange in CELSS Growth rate study of canavalin single crystals p60 A90-15445 agents, phase 1 p34 A90-16420 [ADA2116481 p62 N90-13037 Phase separated membrane bioreactor - Results from CYCLOTRONRESONANCE model system studies p 60 A90-15447 CONDITIONING (LEARNING) Investigation of resonant acdc magnetic field effects The case for cellulose production on Mars Individual differences in associative learning and [ADA2116121 p37 N90-12159 [AAS PAPER 87-2321 p80 A90-16531 forgetting CYTOLOGY A diagnostic and environmental mnitoring system [ADA2127651 p54 N90-13034 Cell mechanisms of adaptation to main factors of space (DEMS) concept to support manned Mars in -flight and CONFERENCES flight surface operations Life sciences and space research XXlll(5)~Gravitational [IAF PAPER 89-6061 p23 AW-13634 [AAS PAPER 87-2341 p 60 A90-16533 biology; Proceedings of the Topical Meeting and Polarity of root statocytes in space and in simulated A zerc-g CELSSlrecreation facility for an earthlMars Workshops XVll and XVlll of the 27th COSPAR Plenary microgravity crew shuitle Meeting, Espoo, Finland, July 18-29. 1988 [IAF PAPER 89-6081 p 23 A90-13636 p25 A90-15051 [AAS PAPER 87-2351 p61 A90-16534 Response of unicellular organisms to the wnditions in COALESCING Life sciences and space research XXlll(3): Natural and low earth orbii Gas bubble coalescence in reduced gravity conditions artificialecosystems; Proceedings of the Topical Meetings [IAF PAPER 895101 p24 A90-13638 p 30 A90-15446 of the 27th COSPAR Plenary Meeting, Espoo, Finland. Plant cell in the process of the adaptation to simulated COBALT July 18-29. 1988 p 57 A90-15426 microgravity p25 A90-15054 Radiwotective properties of a Co(lll) biocomplex International Union of Physiological Sciences p 33 A90-15634 Formation and growth of callus tissue of Arabidopsis Commission on Gravitational Physiology, Annual Meeting, under changed gravity p 25 A90-15055 COCKPIT SIMULATORS 10th. Montreal, Canada, Oct. 9-14. 1988. Proceedings Spatial tests for aviators p 42 A90-15477 Calcium gradient in plant cells with polarized growth in simulated microgravity p26 A90-15056 [ IZF-1988-151 p63 N90-13041 Heatstroke pathophysiology: The energy depletion Effects of prolonged exposure of lettuce to HZE COGNITION model seeds Adaptive informabon processing in auditory cortex [AD42121561 p47 N90-12164 particles on orbii stations p26 A90-15058 Ultrastructural and growth indices Chlorella culture [ADA2112941 p47 N90-12166 Exertional heatstroke: An international perspective. An of in mukicomponent aquatic systems under space flight Metacognition and retrieval irom long-term memory at introduction: The role of exercise in the etiology of p 27 ASO-15063 Mount Everest exectional heatstroke conditions [ ADA21 16291 p52 N90-12177 [AD42122421 p50 N90-13020 Long clinostation influence on the localition of free The effect of incentives on the reliability and validity of Sound Localization by Human Observers symposium and weakly bound calcium in cell walls of Funaria cogniike speed tests hygrometrica moss protonema cells p 27 A90-15064 [ADA2113461 p62 N90-12181 proceedings [ADA2128771 p51 N90-13026 A step in emhonic axis specification in Xenopus laevis Individual differences in associative learning and CONSCIOUSNESS is simulated by cytoplasmic displacements elicited by forgetting gravity and centrifugal force p28 A90-15073 [ADA2127651 p 54 N90-13034 Recovery to +1Gz and +2Gz following +Gz-induced loss of consciousness - Operational considerations The amphibian egg as a model system for analyzing Spatial tests for aviators gravity effects p28 A90-15074 [IZF-1988-15] p63 N90-13041 p41 A90-13741 Subcellular components of the amphibian egg Insights COLD WEATHER CONTAMINANTS - provided by gravitational studies p 28 A90-15075 Effects of serial wetdry-wet cold evosure: Thermal The rodent research animal holding facility as a banier balance, physical activity, and cognitiveperformance to environmental contamination Continuing studies of 'CELLS flight hardware [AD-A212704] p 51 N90-13025 [NASA-TM-102237] p35 N90-12151 p32 A90-15497 COLOR VISION Effects of atmospheric mix and toxic fumes on military Cellular and molecular mechanisms of high pressure Eye movements end spatial pattern vision performance inotrqy in cardiac muscle [ADA21 16501 p48 N90-12169 IPB89-2236301 p49 N90-13015 [ADA2116951 p48 N90-12170

A-4 SUBJECT INDEX EYE MOVEMENTS

CYTOPLASM EARTH ORBITAL ENVIRONMENTS ETIOLOGY A step in embryonic axis specMiation in Xenopus laevis Response of unicellular organisms to the conditions in Exertional heatstroke: An international perspectie. An is simulated by cytoplasmic displacements elicited by low earth orbit introduction: The role of exercise in the etiology of gravity and centrifugalforce p 28 A90-15073 [IAF PAPER 89-6101 p24 A90-13638 exertional heatstroke EATlNQ [ADA2122421 p 50 N90-13020 Air Force fliiht feeding. Volume 1: Evaluation of current EUROPEANSPACE AGENCY D system and alternative concepts Studies on Habitation Module and interconnecting [AD-A212789] p63 N90-13043 elements for a future European space station DARK ADAPTATION EFFERENT NERVOUS SYSTEMS [IAF PAPER 894921 p55 A90-13305 Three stages and two systems of visual processing Age-related changes in human posture control: Motor EUROPEANSPACEPROGRAMS [AD-A212670] p53 N90-13032 coordination tests West Germany's first space robot p 57 A90-149B9 DARKNESS [NASA-CR-185855] p61 N90-12178 EVOKED RESPONSE () EGGS A Scheiner-principle pocket optometer for Dependence of the amplitude of kinesthetic evoked self-evaluation and biofeedback accommodation training The amphibian egg as a model system for analyzing potentials on the velocity and acceleration of the motion gravity effects p 28 A90-15074 [AD-A213171] p 51 N90-13027 of a monkey's hand p 24 A90-14446 ELECTROLYTE METABOLISM DATA ACOUlSlTlON Electrophysiological studies of visual attention and Air Force flight feeding. Volume 1: Evaluation of current Cardovaacular. renal, electrdyle, and homnal resource allocation changes in man during gravitational stress, system and alternative concepts [AD-A2122871 p 53 N90-13030 [ADA2127891 p63 N90-13043 weightlessness. and simulated weightlessness: Lower body positive pressure applied by the anwravity sun EXERCISE PHYSIOLOGY DATA PROCESSING Responses to changed perfusion pressure in working Effects of body posture on the interpretation of [NASA-TM-102232] p49 N90-13013 muscles ~ Factors to be considered in exercise testing in ELECTROLYTES biomediil data obtained from manned missions space flights? p42 A90-15481 [IAF PAPER 89-5961 p39 A90-13628 Heat exhaustion [ADA21 21281 p49 N90-13014 Increasing central blood volume with head-down tilting DECISION MAKING would inhibit water intake during mild pedaling at 25 C ELECTROMAGNETIC FIELDS Three stages and two systems of visual processing and 35 C room temperatures in woman Calcium displacement caused by electromagnetic [ADA2126701 p 53 N90-13032 p45 A90-15510 DECOMPRESSION SICKNESS fields [AD-A212690] p50 N90-13023 Exercise strategies and assessment of cardiorespiratory Probable bends at 14.000 feet - A case report fitness in space ELECTROMAGNETIC NOISE p41 A90-13744 [AAS PAPER 87-2361 p46 A90-16535 Sound Localization by Human ObseNers symposium DEEP SPACE NETWORK Exertionai heatstroke: An international perspective. An The NASA SET1 sky survey: Recent developments proceedings [ADA21 28771 p51 N90-13026 introduction: The role of exercise in the etiology of p 64 N90-12804 exertional heatstroke ELECTROMAGNETIC RADIATION DEGRADATION [ AD-AZl22421 p 50 N90-13020 Shape instabilities of plate-like structures. 1: Accumulation of the biological effects of microwaves as displayed in the behavior, the physical efficiency, the Prediction of thermal stress casualties Experimental observations in heavily cold worked in situ [AD-A212356] p 50 N90-13022 composites body-mass increase, and the condition of cerebral neurons p33 A90-15637 EXHAUSTGASES [ADA2122511 p50 N90-13021 Effects of atmospheric mix and toxic fumes on military DEHYDRATION Characteristics of the response of animals belonging to various typological groups to high-frequency and performance Heat exhaustion [PB89-223630] p49 N90-13015 [ AD-A2121 281 p49 N90-13014 microwave electromagnetic radiation p 34 A90-15638 ELECTROMECHANICAL DEVICES EXHAUSTION DENTISTRY The effect of caffeine on endurance time to exhaustion Astronaut interdisciplinary and medicalldental training The effect of concurrent strength and endurance training on electromechanical delay, maximum voluntary at high altitude for manned Mars missions [ AD-AZl2069) p47 N90-12163 [AAS PAPER 87-2381 p 46 A90-16537 contraction. and rate of force development [AD-A213316] p 51 N90-13028 EXOBIOLOQY DESYNCHRONIZATION (BIOLOGY) Prospects of studies in space phytobiolcgy Effects of a time zone shift of nine hours on the circadian ELECTROMYOGRAPHY Age-related changes in human posture control: Motor [IAF PAPER 89-5781 p23 A90-13617 rhythms in cockpit aircrew members on longhaul flights Cell mechanisms of adaptation to main factors of space [DLR-FB89-31] p49 N90-13019 coordination tests [NASAGR-185855] p61 N90-12178 fliiht DIFFERENTIATION (BIOLOGY) EMBRYOLOGY [IAF PAPER 89-6061 p 23 A90-13634 Subcellular components of the amphibian egg - Insights Polarity of root statocytes in space and in simulated prwided by gravitational studies p 28 A90-15075 Developmental biology in space - Why and hmv7 p 27 A90-15070 microgravity DIGESTIVE SYSTEM [IAF PAPER 89-6081 p 23 A90-13636 Long-term exposure to zerog and the gastro-intestinal Insects as test systems for assessing the potential role of microgravity in biological development and evolution Response of unicellular organisms to the conditions in tract function low earth orbit [IAF PAPER 89-5691 p37 A90-13610 p27 A90-15071 A step in embryonic axis specification in Xenopus laevis [IAF PAPER 89-6101 p24 A90-13638 DISORIENTATION Gravitational biology within the German microgravity Spatial tests for aviators is simulated by cytoplasmic displacements elicited by gravity and centrifugal force p28 AW-15073 program - Current status and further pursuits [ IZF-1988-151 p63 N90-13041 [IAF PAPER 89-6121 Subcellular components of the amphibian egg Insights p24 A90-13640 DISPLACEMENT - Thin film bioreactors in space p 27 A90-15068 provided by gravitational studies p 28 A90-15075 Calcium displacement caused by electromagnetic Biophysical principles of the effects of cosmic rays and fields Fertilization of frog eggs on a sounding rocket in radiation from accelerators --- Russian book. [APA212690] p50 N90-13023 space p 28 A90-15076 p 34 A90-16047 DISPLAY DEVICES Early development in the mouse ~ Would it be affected A diagnosb and environmental monitoring system State of the art of humanlmachine dialog tool by microgravity? p 28 A90-15077 (DEMS) concept to support manned Mars in -flight and prototypes Light microscopic analysis of the gravireceptor in surface operations [TELECOM-PARIS-89-HOl] p 62 N90-13038 Xenopus larvae developed in hypogravity [AAS PAPER 87-2341 p60 A90-16533 DISTORTION p28 A90-15081 USSR Space Life Sciences Digest, Issue 24 A Scheiner-principle pocket optometer for ENDOCRINE SYSTEMS [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 self-evaluation and biofeedback accommodation training Changes in circadian rhythm of multiple homnes and Aerospace medicine and biology: A continuing [ADA2131711 p51 N90-13027 their relationship with indiiual susceptibility in simulated bibliraphy with indexes (supplement 329) DIVING (UNDERWATER) weightlessness [ NASA-SP-7011(329)1 p48 N90-12173 Effects of serial wetdty-wet cold exposure: Thermal [IAF PAPER 89-5651 p 37 A90-13608 EXPERIMENT DESIGN balance, physical activity, and cognitive performance ENWCRINOLOQY Insects as test systems for assessing the potential role [ADA2127041 p51 N90-13025 USSR Space Life Sciences Digest, Issue 23 of microgravity in biological development and evolution DRUGS [NASA-CR-3922(27)-ISSUE-23] p 36 N90-12154 p 27 A90-15071 Experimental research on the applicabilities of Chinese ENVIRONMENTAL ENGINEERING EXTRATERRESTRIALINTELLIGENCE mediine to space medicine Utilization of white potatoes in CELSS The NASA SET1 sky suney: Recent developments [IAF PAPER 89-601] p39 A90-13633 p58 A90-15431 p 64 N90-12604 EXTRATERRESTRIAL LIFE ENVIRONMENTAL MONITORING DYNAMIC CONTROL billion years ago: Life on Mars? Hints, indiitions. A diagnostic and environmental monitoring system 3.5 Active vibration control for flexible space environment speculations p64 A90-16360 (DEMS) concept to support manned Mars in -flight and use manipulators p60 A90-16522 EXTRATERRESTRIALRADIATION surface operations Biological effects of galactic radiation HZE PWIOSin [AAS PAPER 87-2341 , p60 A90-16533 experiments on the orbital station Salyut 7 E ENZYME ACTIVITY p 26 A90-l!i057 Radwprotectiva affects of ATP and ADP on Effects of prolonged exposure of lettuce seeds to HZE EARPROTECTORS membranebound enzymes p33 A90-15635 particles on orbital stations p 26 A90-l!i058 Shape instabilities of plate-like structures. 1: ENZYMOLOGY EXTRAVEHICULAR ACTIVITY Experimental observations in heavily cold worked in situ USSR Space Life Sciences Digest, Issue 22 Innwatie approaches to the design of bioregeneratiie composites [NASA-CR-3922(26)-l~UE-22] p 35 N90-12153 life suppod systems for advanced missions I [ADA2122511 p50 N90-13021 ERYTHROCYTES [IAF PAPER 894261 p54 A90-13261 Application of active noise reduction for hearing Experiment on 'Diswvery' STS 516 - Aggregation of EYE MOVEMENTS protection and speed intelliiibility imprwement red cells and thrombocytes in heart disease, Eye mwements and spatial pattern vision [ IZF-l988-21] p63 N90-13042 hyperlipidaemia and other conditions p 42 A90-15060 [AD-A211650] p48 N90-12169

A-5 FATIGUE (BIOLOGY) SUBJECT INDEX F G Experimental research on the applicabilities of Chinese medicine to space medicine FATIGUE (BIOLOGY) QAS FLOW [IAF PAPER 89-6011 p 39 A90-13633 Heatstroke pathophysiology: The energy depletion Gas bubble coalexence in reduced gravity conditions Behaviour of single-cell organisms exposed to model p30 A90-15446 hypergravity [ADA2121561 p47 N90-12164 GENE EXPRESSION [IAF PAPER 896071 p 23 A90-13635 Heat exhaustion Genetic engineering of enhanced microbial nitrification Gravitational biology within the German microgravity [ADA2121 281 p49 N90-13014 [ PB89-2083341 p36 N90-12155 program - Current status and further pursuits [IAF PAPER 89-6121 p24 A90-13640 The effect of concurrent strength and endurance training GENES on electromechanical delay. maximum voluntary Genetic engineering of enhanced microbial nitrification Selective hypergravity stimulation: Its effects on the contraction, and rate of force development [ PB89-2083341 p36 N90-12155 human balance and gait functions . A model to assass, [ADA2133161 p51 N90-13028 in normal gravity conditions, some aspects of the Fatigue, pilot deviations and time of day GENETIC ENGINEERING Derhubations induced on human bodv.. bv microaravitv ". [NASA-CR-185369] p62 N90-13035 Genetic engineering of enhanced microbial nitrification conditions [PB89-208334] p36 N90-12155 FEAR [IAF PAPER ST-89-0161 p40 A90-13729 Fear-potentiatedstartle as a model system for analyzing GENETICS Life sciences and mace research XXlIl(5) - Gravitational learning and memory USSR Space Life Sciences Dtgest. Issue 22 biology; Proceedings of the Topic; 'Meeting and [AD-A2121311 p53 N90-13029 [NASA-CR-3922(26)-lSSUE-22] p 35 N90-12153 Workshops XVll and XVlll of the 27th COSPAR Plenary FERTlLlUTlON Genetic engineering of enhanced microbial nitrification Meeting, Espoo. Finland, July 18-29, 1988 Fertilization of frog eggs on a sounding rocket in r PEW-2083341 D 36 N90-12155 p 25 A90-15051 space p28 A90-15076 GEOTROPISM Mirogravity and musculoskeletal system of mammals FIGHTER AIRCRAFT Geotropic sensitivity of hornets p 27 A90-15072 p 25 A9O-15052 Spatial tests for aviators GERMINATION Calcium gradient in plant cells with polarized growth in [IZF-l988-15] p63 N90-13041 Effect of iodine disinfection products on higher plants simulated microgravity p 26 Ago-1 5056 FLEXIBLE SPACECRAFT p29 A90-15438 Gravity and the membranesolution interlace - Active vibration control for flexible space environment GLIDERS Theoretical investigations p 26 A90-15059 use manipulators p 60 A90-16522 Biochemical and physiological changes in glider pilots Plant cell plasma membrane structure and properties FLIGHT CREWS during multihour flihts under clinostaning p 26 A90-15061 Galactic cosmic radiation exposure and associated [ DLR-FB-89-29] p49 N90-13018 Potential sites for the perception of gravity in the acellular health risks for air carrier crewmembers GLUCOSIDES slime mold Physarum polycephalum p 26 A90-15062 p41 A90-13745 Cellular and molecular mechanisms of high pressure Ultrastructural and growth indies of Chlorella culture Occupational injuries suffered by flight attendants while inotropy in cardiac muscle in multicomponent aquatic systems under space flight on board p41 A90-13746 [ADA2116951 p48 N90-12170 conditions p27 A90-15063 FLIGHT FATIGUE GLYCOLYSIS Long clinostation influence on the localization of free Biochemical and physiological changes in glider pilots Heatstroke pathophysiology: The energy depletion and weakly bound calcium in cell walls of Funaria during multihour flights model hygromebiCa.- moss protonema cells P 27 A90-15064 [DLR-FB-89-29] p 49 N90-13018 [ AD-A2121 561 p 47 N90-12164 Developmental biology in space - Why and how? Psychologicalmechanisms involved in the disorientation GOGGLES D 27 A90-15070 of pilots due to flight conditions Visual acuity and stereopsis with night vision goggles Insects as test systems for assessingthe potential role [ETN-89-95014] p 63 N90-13040 [ADA21 15521 p47 N90-12167 of microgravity in biological development and evolution FLIGHT SIMULATION GRAMMARS p27 A90-15071 Fatigue, pilot deviations and time of day Computer generation of a tutorial dialogue Geotropic sensitivity of hornets p 27 A90-15072 [NASA-CR-1853691 p62 N90-13035 [AD-AZl 19761 p46 N90-12162 A step in embryonic axis specification in Xenopus laevis Psychologicalmechanisms involved in the disorientation GRAVIRECEPTORS is simulated by cytoplasmic displacements elicited by of pilots due to flight conditions Prospects of studies in space phytobiology gravity and centrifugal force p 28 A90-15073

[ ETN-69-950141 p63 N90-13040 [IAF PAPER 89-5781 p23 A90-13617 Subcellular components of the amphibian egg ~ Insights FLIGHT SIMULATORS Potential sites for the perceptionof gravity in the acellular provided by gravitational studies p 28 A90-15075 The time course of postflight simulator sickness slime mold Physarum polycephalum p 28 A90-15062 Fertilization of frog eggs on a sounding rocket in symptoms p40 A90-13735 Liht microscopic analysis of the gravireceptor in space p28 A90-15076 FLIGHT STRESS (BIOLOGY) Xenopus larvae developed in hypogravity Early development in the mouse - Would it be affected Effects of a time zone shift of nine hours on the circadian p 28 A90-15081 by microgravity7 p28 A90-15077 rhythms in cockpit aircrew members on longhaul flights GRAVITATIONAL EFFECTS Dorsal light response and changes of its responses [DLR-FB-89-31I p49 N90-13019 Importance of the lgcontrols in interpreting the results under varying acceleration conditions - in goldfish FLIGHT TESTS of an experiment on plant gravitropism (Biorack, D1 28 A90-15080 Air Force flight feeding. Volume 1: Evaluation of current mission) Light microscopic analysis of the gravireceptor in system and alternative concepts [IAF PAPER 89-6091 p24 A90-13637 Xenopus larvae developed in hypogravity [AD-A2127891 p63 N90-13043 Formation and growth of callus tissue of Arabidopsis p28 A90-15081 under changed gravity p 25 A90-15055 Rhythmic biological systems under micro-g conditions FOCUSING p 29 A90-15084 , A Scheiner-principle pocket optometer for Gravity and the membrane-solution interlace - Gravitational biology and the mammalian circadian self-evaluation and biofeedback accommodation training Theoretical investigations p26 A90-15059 timing system p 29 A90-15085 [ADA2131711 p51 N90-13027 The amphibian egg as a model system for analyzing gravity effects p 28 A90-15074 International Union of Physiological Sciences FOOD PRODUCTION (IN SPACE) Rhythmic biological systems under micrc-g conditions Commission on Gravitational Physiology, Annual Meeting, Application of tubular photo-bioreactor system to culture p 29 A90-15084 10th. Montreal, Canada, Oct. 9-14, 1988, Proceedings spirulina for gas exchange and food production in I USSR Space Life Sciences Digest, Issue p 42 Ago-15477 CELSS 22 [NASA-CR-3922(26)-lSSUE.22] p 35 N90-12153 Periodic acceleration stimulation in a weightlessness 1IAF PAPER 89-5771 p56 A90-13616 Cardiovascular, renal, electrolyte, and hormonal environment (PAS-WE) - A nwscience? A foodlnutrient supply plan for lunar base CELSS changes in man during gravitational stress, p30 AM-15479 [IAF PAPER 89-5791 p56 A90-13618 weightlessness, and simulated weightlessness: Lower lnterserosal pressures and circulatory homeostasis Utilization of sweet potatoes in controlled ecological life during changes in the gravitational inertial force I body positive pressure applied by the antigravity suit support systems (CELSS) p 58 A90-15429 [NASA-TM-102232] p49 N90-13013 environment p42 A90-15480 Carbon balance and productivity of Lemna gibba, a GRAVITATIONAL PHYSIOLOGY Responses to changed perlusion pressure in working candidate plant for CELSS p58 A90-15430 Telescience testbed for physiological experiments muscles - Factors to be considered in exercise testing in Long-term experiments on man's stay in biological [IAF PAPER 89-0341 p 37 AM-13267 space flights? p 42 A90-15481 life-support system p58 A90-15433 Biomedical payload of the French-Soviet long duration Changes in kidney response to ADH under hypogravity Productivity and food value of Amaranthus cruentus fliht - First conclusions - Rat models and possible mechanisms I under non-lethalsalt stress p 30 A90-15440 [ IAF PAPER 89-5631 p37 A90-13606 p30 A90-15482 Closed and continuous algae cultivation system for food Long-term exposure to zerc-g and the gastro-intestinal The effect of suspension on nicotinic acetylcholine productbn and gas exchange in CELSS tract function receptor number and affinity at the rat neuromuscular p80 A90-15445 [IAF PAPER 89-5691 p37 A90-13610 junction p31 A90-15483 Prospects of studies in space phflobbbgy Phase separated membrane bioreactor Results from Decreas6d swelling pressure of rat nucleus pulposus - [IAF PAPER 89-5781 p23 A90-13617 model system studies p A90-15447 associated with simulated weightlessness 80 Plant cultural system incorporated into CELSS FREQUENCY CONTROL p31 A90-15485 [IAF PAPER 89-5801 p57 A90-13819 Modifications of bone atrophy seen with hindlimb Three stages and two systems of visual processing Orthostatic intolerance post space flight - A multifactorial [ADA2126701 p53 N90-13032 suspension by exercise and dobutamine diswdeR p31 A90-15487 FUMES [IAF PAPER 89-5951 p39 A90-13627 Effects of atmospheric mix and toxic fumes on mili Biochemical correlates of neurosensory changes in The effect of microgravity on the reproductive function pertorrnance weightlessness of male rats p31 A90-15488 [PB89-223630] p49 N90-13015 [ IAF PAPER 89-5981 p 39 A90-13830 Microgravity-inducedchanges in human bone strength FUNCTIONAL ANALYSIS Fluid distribution oattern induced bv intravenous fluid p43 A90-15493 Visual motion perception loading during HDT ' Immunocompetent cells producing humoral mediators [ADA21 09941 P 46 N90-12180 [IAF PAPER 89-5991 p 39 AW-13631 of bone tissue mineral metabolism during space flight FUNGI Hmnaland cardiovascular changes during lower body SimUlatbn p 43 A90-15496 Potential sitesfor the perception of gravity in the acellular negative and positive pressures Continuing studies of 'CELLS flight hardware dime mold Physarum polycephalum p 26 A90-15062 [IAF PAPER 896001 p39 A90-13632 p 32 A90-15497 SUBJECT INDEX HUMAN FACTORS ENGINEERING

Skeletal muscle antioxidant enzyme levels in rats after HEAD MOVEMENT HlQH ALTITUDE ENVIRONMENTS simulated weightlessness, exercise and dobutamine Yaw senswy rearrangement changes pitch responses Metawgnition and retrieval from long-term memory at p 32 A90-15498 --- in human head movement and ocular response Mount Everest Temperature regulation in rats exposed to a 2 G field [IAF PAPER ST-89-0121 p40 A90-13727 [ADA2116291 p52 N90-12177 p 32 A90-15499 HEARINQ HIGH GRAVITY ENVIRONMENTS Effect of iwxeased acceleration on lung expansion in Adaptive information processing in auditory cortex Behaviour of sinnle-cell oroanisms exwsed to dogs - Prone vs. supine body positions [ADA2112941 p47 N90-12166 hypergravity p33 A90-15500 Shape instabilities of platelike structures. 1: [IAF PAPER 894071 p23 A90-13635 Changes of muscle function and size with bedrest Experimental observations in heavily cold worked in situ Selective hypergravity stimulation: Its effects on the composites p43 A90-15501 human balance and gait functions ~ A model to assess, Plasma ANF concentrations during headdorm bed rest [ADA2122511 p50 N90-13021 in normal gravity conditions, some aspects of the of various duration (from several hours to one month) - Application of active noise reduction for hearing perturbations induced on human body by microgravity Role of LBNP countermeasure p 44 A90-15503 protection and speech intelligibility improvement conditions Central venous pressure in humans during short periods [IZF-1988-21] p 63 N90-13042 [IAF PAPER ST-89-0161 p40 A90-13729 HEART of weighnessness p 44 A90-15504 Temperature regulation in rats exposed to a 2 G field Cardorespiratory responses to simulated Cellular and molecular mechanisms of hgh pressure p 32 A90-15499 inotropy in cardiac muscle weightlessness in man p44 A90-15505 HIGH PRESSURE Gravitational influence on systemic arterial &ynamics [ADA2116951 p48 N90-12170 HEART DISEASES Cellular and molecular mechanisms of high pressure using a 34ement Windkessel model p 44 A90-15506 inotropy in cardiac muscle Regional aortic pressure apparent phase velocity in the Experiment on 'Discovery' STS 51-C - Aggregation of red cells and thrombocytes in heart disease, [ADA2116951 p 48 N90-1217'0 baboon during 70 degree tilt p 44 A90-15507 hyperlipidaemiaand other conditions p 42 A90-15060 HISTOLOGY Hemodynamics of leg veins during a 30 days bed rest Biochemical and histochemical obsewations of vastus Effect of lower body negative pressure (LBNP) Effects of transition from supine to upright positions on - central hemodynamics in patients with chest pain medialis from rats flown in Cosmos 1887 (experiment p45 A90-15508 K608) p 31 A90-15484 Pilot performance is increased after alternating hypo- syndrome p 43 A90-15490 HEART FUNCTION Changes of muscle function and size with bedrest and hypergravity states p45 A90-15511 p 43 A90-15501 Life beyond gravily p 45 A90-16299 Effect on the cardiac function of repeated LBNP during Space physiology and medicine (2nd edii)-_- Book a one month head down tilt HOMEOSTASIS p46 A90-16625 [IAF PAPER 8s-5931 p 38 A90-13625 lnterserosal pressures and circulatory homeostasis Cardiivascular. renal, electrolyte, and homnal HEART RATE during changes in the gravitational inertial force changes in man during gravitational stress, The effect of caffeine on endurance time to exhaustion environment p 42 AM-154130 weightlessness, and simulated weightlessness: Lower at hgh altitude Calcium homeostasis in prolonged hypokinesia body positive pressure applii by the antigravity suit [ADA2120691 p47 N90-12163 p43 A90-15492 [NASA-TM-102232] p 49 N90-13013 HEAT HORMONE METABOLISMS GRAVITROPISM Heat exhaustion Changes in kidney response to ADH under hypogravity Importance of the lgcontrols in interpreting the results [ADA2121281 p49 N90-13014 - Rat models and possible mechanisms of an experiment on plant gravitropism (Binrack. D1 HEAT ACCLIMATIZATION p30 A90-15482 Exertional heatstroke: An international perspective. An mission) Plasma stress hormones in resting rats ~ Eighty four [IAF PAPER 89-6091 p24 A90-13637 introduction: The role of exercise in the etiology of day study p 32 Ago-1 5489 Evaluation of experiments involving the study of plant exerlional heatstroke [ADA2122421 p 50 N90-13020 Plasma ANF concentrations during headdown bed rest orientation and growth under different gravitational of various duration (from several hours to one month) - conditions p 25 A90-15053 HEAT STROKE Heatstroke pathophysiology: The energy depletion Role of LBNP countermeasure p44 A90-15503 GROUND TESTS HORMONES A report of ground results for brain function experiments model [AD-A212156] p47 N90-12164 Changes in circadian rhythm of multiple hormones and in space their relationship with individual susceptibility in simulated [IAF PAPER 89-5901 p 38 A90-13624 ExeMnal heatstroke: An international perspective. An introduction: The role of exercise in the etiology of weightlessness GROUP DYNAMICS [ IAF PAPER 89-5651 p37 A90-13608 Significance of light and social cues in the maintenance exerlional heatstroke Hormonaland cardiovascular changes during lower body of temporal organization in man p 45 A90-15512 [ AD-AZl22421 p50 N90-13020 HEAT TOLERANCE negative and positive pressures Head cooling is desirable but not essential for preventing [IAF PAPER 89-8001 p 39 A90-13632 H heat strain in pilots p57 A90-13737 Cardiovascular, renal, electrolyte. and hormonal HELICOPTERS changes in man during gravitational stress. HABITABILITY The occurrence of the vection illusion among helicopter weightlessness, and simulated weightlessness: Lower lndiiual differences, mission parameters, and pilots while flying over water p 52 A90-13743 body positive pressure applii by the antigravity suit spaceflight environment habitability [ NASA-TM-1022321 p49 N90-13013 HEMODYNAMIC RESPONSES [MS PAPER 87-2401 p61 A90-18539 HUMAN BEHAVIOR Considerations for the living areas within space Hemodynamics during head down tilting and lower body negative pressure and pharmacological interventions for Demonstration of replicable dimensions of health senlements countermeasures behaviors [MS PAPER 87-2421 p61 A90-16541 [IAF PAPER 89-5971 p 39 A90-13629 [ADA2119201 p46 N90-12161 HABITS Fear-potentiatedstartle as a model system for analyzing Reduced systolic blood pressure elevations during Demonstration of replicable dimensions of health learning and memory behaviors maximum exercise at simulated altitudes [AD-A212131] p53 N90-13029 [ADA2llQZO] p46 N90-12161 p 40 A90-13738 HUMAN BEINGS HAND (ANATOMY) Effects of transition from supine to upright positions on Individual differences in associative learning and Dependence of the amplitude of kinesthetic evoked central hemodynamics in patients with chest pain forgetting potentials on the velocity and acceleration of the motion syndrome p43 A90-15490 [ADA2127651 p 54 N90-13034 of a monkey's hand p 24 AM-14446 HEMODYNAMICS HUMAN BODY HAZARDS Fluid distribution pattem induced by intravenous fluid Effects of transition from supine to upright positions on Base level management of radio frequency radiation loading during HDT central hemodynamics in patients with chest pain protection program [IAF PAPER 89-5993 p39 A90-13631 syndrome p 43 A90-15490 [ADA21 17871 p48 N90-12171 Gravitational influence on systemic arterial dynamics Predicting the postradiative radiosensitivity of mammals Base level management of radio frequency radiation using a 3-element Windkessel model p 44 A90-15506 and man according to the LD5O criterion after acute protection program Regional aortic pressure apparent phase velodty in the external irradiation p34 A90-15M9 [ADA2117591 p49 N90-13017 baboon during 70 degree tilt p44 A90-15507 HUMAN CENTRIFUQES HEAD (ANATOMY) Hemodynamics of leg veins during a 30 days bed rest Unilateral centrifugation of the otoliths as a new method Head woling is desirable but not essential for preventing - Effect of lower body negative pressure (LBNP) to determine bilateral asymmetries of the otolith apparatus heat strain in pilots p57 A90-13737 p 45 A90-15508 in man HEAD DOWN TILT Difference in cardovascular responses to blood pooling [IAF PAPER 89-5681 p37 A90-13609 Effect on the cardiac function of repeated LBNP during patterns between LBNP and head up tilting stimulated after Influence of gravitoinertialforce on vestibular nystagmus a month head tin one down supine cycling in women p45 A90-15509 in man observed in a centrifuge p 42 A90-15078 i [IAF PAPER 89-5931 p 38 A90-13625 HUMAN FACTORS ENQINEERING Hemodynamics during head down tilting and lower body Increasing central blood volume with headdown tilting Human factors and productivity on Space Station would inhibit water intake during mild pedaling at 25 C negative pressure and phammdogii interventions for Freedom and 35 C room temperatures in woman countermeasures [IAF PAPER 89-0871 p55 A90-13301 p45 A90-15510 [IAF PAPER 885971 p39 A90-13829 Simulation by personal workstation for Man-Machine Fluid distributDn pattern induced by intravenous fluid HIBERNATION Interface design loading during HDT Neurochemistry of hibernation in mammals --_ Russian [IAF PAPER 89-0891 p 55 A90-13:302 [ IAF PAPER 89-59!3] p39 A90-13631 book p34 AM-16057 The next 40 years in space - Aspects of human factors Plasma ANF concentrations during headdown bed rest HIGH ALTITUDE in space research of various duration (from several hours to one month) - Propranololand the compensatorycirculatoryresponses [ IAF PAPER 89-091] p37 A90-13304 Role of LBNP countermeasure p44 A90-15503 to orvlostasis at hQh anitude p40 A90-13736 Using computer graphics to design Space Station Increasing central blood volume with head-down tilting HlQH ALTITUDE BREATHING Freedom viewing would inhibit water intake during mild pedaling at 25 C The effect of caffeine on endurance time to exhaustion [IAF PAPER 89-0931 p56 A90-13306 and 35 C room temperatures in woman at hgh altitude The effects of automation on work in space p45 A90-15510 [ADA2120691 p47 N90-12163 [IAF PAPER 89-5831 p57 A90-13620

A-7 HUMAN FACTORS LABORATORIES SUBJECT INDEX

A zerog CELSSlrecreation facility for an earthlMars IMMUNE SYSTEMS K crew shuttle Study of activation of human peripheral blood [AAS PAPER 67-2351 p 61 A90-16534 mononuclear cells after a space fliht KIDNEYS I Individual differences. mission parameters. and llAF PAPER 89-6111 D 24 A90-13639 Chanaes in kidnev reswnse to ADH under hwaravitv _. " . speceflight environment habitability Immunocompeten; cells producing humoral mediators - Rat rn&els and possible mechanisms [AAS PAPER 87.2401 p 61 A90-16539 of bone tissue mineral metabolism during space flight p30 A90-15482 Considerations for the living areas within space 43 ~90-154~ KINESTHESIA settlements Dependence of the amplitude of kinesthetic evoked [AAS PAPER 87-2421 p 61 A90-16541 lMMUNoLmY producing humoral mediators potentials on the velocity and acceleration of the motion Wrist orientation effect on grip strength and of bone tissue mineral metabolism durino soace fliaht of a monkey's hand p 24 A90-14446 ^..A,._ ^_^^ IINYIIII~~ [ PB69-2009351 p61 N90-12179 simulation p l3 'A90-15496 Psychologicalmechanisms involved in the di-ntation IN-FLIGHT MONITORING L of pilots due to flight conditions The C23A - First step to a monitoring system of CELSS [ETN-69-95014] p 63 N90-13040 in fliht p 59 A90-15437 LEARNING HUMAN FACTORS LABORATORIES INCENTIVES Synaptic plasticity and memory formation Psychologicalmechanisms involved in the disorientation The effect of incentives on the reliability and validity of [AD-A211368] p 36 N90-12156 of pilots due lo fliht conditions cognitive speed tests Adaptive infmation processing in auditory cortex [ ETN-69-950141 p 63 N90-13040 [AD-A211346] p62 N90-12181 [AD-A211294] p 47 N90-12166 Fear-potentiatedstartle as a model system for analyzing HUMAN PERFORMANCE . INDEXES (DOCUMENTATION) Selective hypergravity stimulation: Its effects on the learning and memory Aerospace medicine and biology: A continuing [AD-A212131 ] p53 N90-13029 human balance and gait functions ~ A model to assess, bibliography with indexes (supplement 329) Effects of type of responding on memorylvisualsearch in mlgravity condins, some aspects of the [NASA-SP-7011(329)] p 48 N90-12173 perturbations induced on human body by microgravity Responding just yes or just no can lead to inflexible conditions INERTIA performance [IAF PAPER ST-89-0161 p 40 A90-13729 Influence of gravitoinertial force on vestibular nystagmus [ADA21 27641 p53 N90-13033 USSR Space life Sciences Digest, Issue 24 in man observed in a centrifuge p 42 A90-15078 LEG (ANATOMY) [NASA-CR-3522(26)-ISSUE-24] p 35 N90-12152 INFORMATION PROCESSING (BIOLOGY) Responses to changed perfusion pressure in working USSR Space Lie Sciences Digest. Issue 23 Adaptive information processing in auditory cortex muscles - Factors to be considered in exercise testing in [NASA-CR-3922(27)-lSSUE-23] p 36 N90-12154 [ADA2112941 p47 N90-12166 space flights? p 42 A90-15481 Adaptive information processing in auditory cortex LIFE SCIENCES Metacognition and retrieval from long-term memory at The Life Sciences program at the NASA Ames Research [AD-AZl 12941 p47 N90-12166 Mount Everest Center - An overview p30 A90-15478 Effects of atmospheric mix and toxic fumes on military [AD-A211629] 052 N90-12177 performance Prbbiotic organic matter from comets and asteroids [PB89-223630] p49 N90-13015 Electrophysiological studies of visual attention and p64 A90-16160 Effects of serial wet-dry-wet cold exposure: Thermal resource allmation USSR Space Life Sciences Digest. Issue 24 balance, physical activity, and cognitive performance [ADA2122671 p53 N90-13030 [NASA-CR-3922(26)-lSSUE-241 p 35 N90-12152 [ADA2127041 p51 N90-13025 INJURIES LIFE SUPPORT SYSTEMS HUMAN TOLERANCES Occupational injuries suffered by flight attendants while Innovative approaches to the design of bioregenerative Heat exhaustion on board p41 A90-13746 life support systems for advanced misswns [AD-A212128] p49 N90-13014 Exertional heatstroke: An international perspective. An [IAF PAPER 89-0261 p 54 A90-13261 HUMAN WASTES introduction: The role of exercise in the etiology of Oxygen separation system of residential space at the Proposal for a zerogravity toilet facility for the space exertional heatstroke lunar base station [ AD42122421 p50 N90-13020 [IAF PAPER 69-5741 p 56 A90-13613 [NASA-CR-183151] p62 N90-13036 A study on culturing modules for CELSS in lunar base INSECTS [IAF PAPER 89-5761 p56 A90-13615 HYDROCYANIC ACID Geotropic sensitivity of hornets p 27 A90-15072 Effects of atmosphecic mix and toxic fumes on military Application of tubular photo-bioreactor system to culture performance INSULIN spirullna for gas exchange and food production in [ PB69-223630] p49 N90-13015 Effect of space flights and hypokinesiaon plasma insulin CELSS HYDROPONICS levels and insulin receptors in rat liver [IAF PAPER 69-5771 p56 A90-13616 A study on culturing modules for CELSS in lunar base [IAF PAPER 89-5641 p 23 A90-13607 Utilization of white potatoes in CELSS [IAF PAPER 89-5761 p56 A90-13615 INTERFACES p58 A90-15431 Utilization of sweet potatoes in controlled ecological life State of the art of humanlmachine dialw tool The role of computerized modeling and simulation in supmi systems (CELS) p 58 A90-15429 prototypes the development of lie support system technologies HYDROSTATIC PRESSURE [TELECOM-PARIS69-H001I p 62 N90-13038 p 59 A90-15439 lnterserosal pcessures and circulatory homeostasis INTERPLANETARY FLIGHT USSR Space Life Sciences Digest, Issue 24 during changes in the gravitational inertial force Innovative approaches to the design of biOregeneratNe [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 environment p 42 A90-15480 life support systems for advanced missions USSR Space Life Sciences Dist. Issue 23 Cellular and molecular mechanisms of high pressure [IAF PAPER 89-0261 p54 A90-13261 [NASA-CR-3922(27)-ISSUE-231 p 36 N90-12154 inotropy in cardiac muscle [ADA21 16951 p48 N90-12170 INVENTORIES LIGHT (VISIBLE RADIATION) HYPERTHERMIA Air Force flight feeding. Volume 1: Evaluation of cunent Sgnificance of light and social cues in the maintenance Heatstroke pathophysiology: The energy depletion system and alternative concepts of temporal organization in man p 45 A90-15512 [ AD-AZl 27891 p63 N90-13043 model LINE OF SIGHT [ADA2121561 p47 N90-12164 ION DENSITY (CONCENTRATION) The time required for U.S. Navy fighter pilots to shift

Exertional heatstroke: An international perrpectve. An Gravity and the membrane-solution interface ~ gaze and identify near and far targets introduction: The role of exercise in the etiology of Theoretical investigakns p26 A90-15059 p41 A90-13740 exertional heatstroke IONIZING RADIATION A Scheiner-principle pocket optometer for [ADA2122421 p 50 N90-13020 Effects of pfolonged exposure of letluce seeds to HZE self-evaluation and biofeedback accommodation training HYPOKINESIA particles on orbital stations p 26 A90-15058 [ADA2131 71 ] p51 N90-13027 LIPIDS Effect of space flihts and hypokinesiaon plasma insulin Prevention of radiation sickness. induced by low-level Membrane fusion: The role of polyphosphatidylinositol levels and insulin receptors in rat liver ionizing radiation, by repeated injections with increasing [IAF PAPER 89-5641 p 23 A90-13607 doses of chemical radioprotectors p 33 A90-15633 [AD-A211269] p36 N90-12156 Calcium homeostasis in prolonged hypokinesia LIQUID WASTES Effect of ionizing radiation on the binding of muscimol p43 A90-15492 Subcritical and supercritical water oxidation of CELSS HYPOTHERMIA by synaptic membranes of the rat brain p A90-15640 model wastes p 59 A90-15436 Radio frequency (13.56 MHz) energy enhances 34 Effect of ultrahghdose ionizing radiation on the content LONG DURATION SPACE FLIGHT rewarming from mild hypothermia The next 40 years in space - Aspects of human factors [ADA2127031 p 50 N90-13024 of cathecholamine mediators in various regions of the rat brain p34 A90-15641 in space research HYPOXIA [IAF PAPER 69-0911 p37 A90-13304 ISCHEMIA Effects of atmospheric mix and toxic fumes on military Biomedical paydoad of the French.Soviet long duration performance Experiment on 'Discovery' STS 51-C - Aggregation of flight ~ First conclusions [PB89-223630] p49 N90-13015 red cells and thrombocytes in heart disease, hypedipidaemia and other codions p 42 A90-15060 [IAF PAPER 69-563 ] p 37 A90-13806 Long-term exposure to zerog and the gastrc-intestinal I tract function J [IAF PAPER 89-5691 p 37 A90-13610 ILLUSIONS Medical results of the flight of the second prime crew A comparison of two subjectcontrolled attitude JET LAG on the orbital station Mir measures during somatogravic illusion exposure Effects of a time zone shift of nine hours on the circadian [IAF PAPER 89-5941 p38 A90-13626 [ADA2125261 p53 N90-13031 mythms in cockptt aircrew members on longhaul flights Microgravity-inducedchanges in human bone strength IMAGE PROCESSING [DLR-FB-89-31] p49 N90-13019 p 43 A90-15493 Disaiminating rigii from nonrigid motion JUDGMENTS Immunocompetent cells producin$ humoral mediators [ADA21 1794] p62 N90-12160 Metacognition and retrieval from long-term memory at Of bone tissue mineral metabolism during space flight Three stages and two systems of visualprocessing Mount Everest simulation p43 A90-15496 [ADA2126701 p 53 N90-13032 [AD-A211629] p52 N90-12177 Life beyond gravity p45 A90-16299

A-8 SUBJECT INDEX MUSCLES

Exercise stratecriesand assessment of cardoresDiratocv.. MANIPULATOR$ MICROBIOLOGY fitness in space Design guidelines for accommodation of robotic and Behaviour of single-cell organisms exposed to [AAS PAPER 87-2361 p46 A90-16535 manipulative devices on Space Station Freedom hypergravity Work on human adaptation to long-term space fliht in [IAF PAPER 894841 p 55 A90-13300 [IAF PAPER 89-6071 p 23 A90-13635 the UK Active vibration control for flexible space environment A diagnostic and environmental monitoring system [AAS PAPER 87-2371 p46 A90-16536 use manipulators p60 Am16522 (DEW conceDt to SUDW~~.. manned Mars in -Riht and Automation of fitness management for extended space MANNED MARS MISSIONS &a& operations missions Utilization of while potatoes in CELSS [AAS PAPER 67-2341 p 60 A90-16533 [AAS PAPER 87-2391 p46 A90-16538 p58 A90-15431 MICROCOMPUTERS LONG TERM EFFECTS Space Station accommodationof life sciences in Support Microcomputer-based tests for repeated-measures: Long-term experiments on man% stay in biological of a manned Mars mission Metric properlies and prediictive valii liesupport system p58 A90-15433 [AAS PAPER 87-2331 p35 A90-16532 [NASA-CR-t85517] p52 N90-12174 LOWER BODY NEGATIVE PRESSURE A diagnostic and emrimmental monitoring system A menu of self-administered microcomputer-based Effect on the cardiac function of repeated LBNP dwing (DEMS) concept to support manned Mars in -fl!!ht and neurotoxiwlogy tests a one month head down tilt surface operations [NASA-CR-185518] p52 N90-12175 [IAF PAPER 89-5933 p 36 A90-13625 [AAS PAPER 87-2341 p 60 A90-16533 MICROGRAVITY APPLICATIONS Hemodynamics during head down tilting and lower body A zerog CELSSlrecreation facility for an earthMars Thin film bwreactors in space p 27 A90-1506R negative pressure and phannacO(0gical interventions for crew shuttle MICROORGANISMS countermeasures [AAS PAPER 87-2351 p61 A90-16534 Behaviour of single-cell organisms exposed to [IAF PAPER 89-5971 p39 A90-13629 Astronaut interdisciplinary and medicalldental training hypergravity Honnonalandcardiovasarlarchen~asduringlower body for manned Mars missions [IAF PAPER 89-6071 p 23 A90-13635 negative and positive pressures [AAS PAPER 87-2381 p46 A90-16537 Response of unicellular organisms to the conditions in [IAF PAPER 89-6001 p39 A90-13632 MANNED SPACE FLIGHT low earth orbii Plasma ANF concentrations during headdown bed rest Innovative approaches to the design of Moregenerative [IAF PAPER 89-6101 p 24 A90-13638 of various duration (hom several hours to one month) - lie support systems for advanced missions MICROSCOPY Role of LBNP countermeasure p 44 A90-15503 [IAF PAPER 89-0261 p54 A90-13261 Light microscopic analysis of the gravireceptor in Hemodynamics of leg veins during a 30 days bed rest The next 40 years in space - Aspects of human factors Xenopus Iwae developed in hyposravity - Effect of lower body negative pressure (LBNP) in space research p28 A90-15081 p45 A90-15508 [IAF PAPER 894911 p37 A90-13304 MILITARY AIRCRAFT Difference in cardiovascular responses to blood pooling Effects of body posture on the interpretation of Deep venous thrombosis in the military pilot patterns between LBNP and head up tilting stimulated after biomedical data obtained from manned missions p41 A90-13742 supine cycling in women p 45 A90-15509 [IAF PAPER 89-5961 p39 A90-13628 MILITARY HELICOPTERS LUMINANCE Space physiology and medicine (2nd edition) -- Book The effect of occupational work load on the functional Three stages and two systems of visual processing p46 A90-16625 state of naval-aviation flight personnel [ADA21 28701 p53 N90-13032 MARS (PLANET) p41 A90-14425 LUNARBASES 3.5 billii years ago: Lie on Mars? Hints, indications, MINERAL METABOLISM The basic health care system for the crew lunar base speculations p 64 A90-16360 Immunocompetent cells producing humoral mediators [IAF PAPER 89.5731 p36 A90-13612 MARS ATMOSPHERE of bone tissue mineral metabolism during space flight Oxygen separation system of residential space at the The case for cellulose production on Mars simulation p 43 A90-15496 lunar base [AAS PAPER 87-2321 p60 A90-16531 MIR SPACE STATION [IAF PAPER 89-5741 p56 A90-13613 MARS ENVIRONMENT Medical results of the flight of the second pime crew Study on the nitrcgen fixation system required for plant The case for cellulose production on Mars on the orbital station Mir culture in a lunar base [AAS PAPER 87-2321 p60 A90-16531 [IAF PAPER 89-5941 p38 A90-13626 [IAF PAPER 89-5751 p56 A90713614 MASS TRANSFER MISSION PLANNING A study on culturing modules for CELSS in lunar base Human body regional convective heat transfer The effects of automation on work in space [IAF PAPER 89-5761 p56 A90-13615 determination using sublimating naphthalene disks [ IAF PAPER 89-5831 p57 A90-13620 A foodlnutrient supply plan for lunar base CELSS [ADA2121701 p47 N90-12165 Robotics and teleoperation p 60 A90-16352 [IAF PAPER 89-5791 p56 A90-13618 MEDICAL SERVICES Space Station accommodationof life sciences in support LYMPHOCYTES Astronaut interdisciplinary and medicalldental training of a manned Mars mission Study of activation of human peripheral blood for manned Mars missions [AAS PAPER 87-2331 p35 A90-16532 mononuclear cells after a space Niht [AAS PAPER 87-2381 p46 A90-16537 MITOSIS [IAF PAPER 89-6111 p24 A90-13639 MEMBRANES Importance of the lgcontrols in interpreting the results Gravity and the membranesolution interface . Of an experiment on plant gravitropism (Biorack, D1 Theoretical investigations p26 A90-15059 mission) M Effect of ionizing radiation on the binding of muscimol [ IAF PAPER 89-6091 p24 A90-13637 by synaptic membranes of the rat brain MNEMONICS MAGNETIC EFFECTS p 34 A90-15840 Three stages and two systems of visual processing Investigation of resonant acdc magnetic field effects Membrane fusion: The role of polyphosphatiinositol [ADA21 26701 p53 N90-13032 [ADA21 16121 p37 N90-12159 [ADA2112891 p36 N90-12156 MAGNETIC FLUX Cellular and molecular mechanisms of high pressure Calcium displacement caused by electromagnetic InvestLgation of resonant ac-dc magnetic field effects inotropy in cardiac muscle fields [AD-A211612] p37 N90-12159 [AD-A211695] p 48 N90-12170 [AD-A212690] p50 N90-13023 MAMMALS MORPHOLOGY MEMORY Predicting the postradiative radiosensitivity of mammals Potential sitesfor the perceptionof gravity in the acellular and man according to the LDW criterion after acute Synaptic plasticity and memwy formation slime mold Physarum polycephalum p 26 A90-15062 extemal imadiatwn P34 A90-15639 [ADA21 13681 p 36 N90-12158 Early development in the mouse -Would it be affected Neurochemistry of hibemation in mammals - Russian Metacognition and retrieval hom long-tern, memory at by microgravity? p 28 A90-15077 book p 34 A90-16057 Mount Everest MOTION PERCEPTION Sound Localition by Human Observers symposium [ADA2116291 p52 N90-12177 Visual motion perception proceedings Fear-potentiatedslarlle as a model system for analyzing [APA210994] p46 N90-121fii [ADA2128771 p51 N90-13026 learning and memory Discriminating dgkl from nonrigid motion MAN MACHINE SYSTEMS [AD4212131 ] p53 N90-13029 [AD-A211794] p62 N90-12180 Human factors and productivity on Space Statwn Effects of type of responding on memorylvisualsearch MOTION SICKNESS Freedom Responding just yes or just no can lead to inflexible Unilateral centrifugation of the otoliths as a new method [IAF PAPER 89-0871 p55 A90-13301 performance to determine bilateral asymmetries of the otoliih apparatus Simulation by persod workstation for Man-Machine [ADA2127641 p 53 N90-13033 in man Interface design Individual differences in associative learning and [ IAF PAPER 89-5661 p 37 A90-13609 [ IAF PAPER 89-089 ] p 55 A90-13302 fmming @-OH-DPAT suppresse% vomiting in the cat elicited by Design and evaluationof man-in-the-loopcontrol system [AD-A2127651 p54 N90-13034 motion, cisplati or xylazine p34 A9C-16208 of Japanese Experimental Module Remote Manipulator MOTION SICKNESS DRUGS System MENTAL PERFORMANCE A menu of self-administered microcomputer-based 8-OH-DPAT suppresses vomiting in the cat elicited by [IAF PAPER 894901 p55 A90-13303 motion, cisplatin or xyiazine p 34 A90-182H6 The of automation on work in space neurotoxicoroey tests effects [ NASA-CR-t65518] p52 NQO-12175 MOTIVATION [IAF PAPER 89.5831 p57 A90-13620 The effect of incentives on reliability and valii of The of incentives on the reliabili and validity of the Teleoperators p60 A90-15800 effect cognitive speed tests Robotics and teleoperation p60 A90-16352 cognitive speed Iests [ADA21 13461 p62 N90-12161 [ADA2113461 p62 N90-12181 USSR Space Life Sciences Digest, Issue 24 MUSCLES [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 Effects of serial wet+-wet coM exposure: Thermal Responses to changed perfusion pessure in working MANCOMPUTER INTERFACE balance, physical activity. and cognitiveperfmnce muscles - Factors to be considered in exercise testing in State of the art of human/machine dialog tool [ADA2127041 p51 N90-13025 space flights? p42 ~90-154at I pr0~ObP- METABOLITES Biochemical and histochemical obwwationa of vastus [TELECOM-PARIS89-H001] p62 N90-13038 Prediction of thermal stress casualties medialis from rats flown in Cosmos 1887 (experiment MANAGEMENT [ADA2123561 p50 NW-13022 p31 A90-15484 Base level management of radio frequency radiation MICE Cellular and molecular mechanisms of high pressure protection program Increasing the radoresistanceof mice with ivastimul inotropy in cardiac muscle [ADA2117591 p 49 N90-13017 p 33 A90-15636 [AD-A211695] p46 N90-12170

A-9 MUSCULAR FATIGUE SUBJECT INDEX

MUSCULAR FATIGUE OPTICAL DATA PROCESSING PEPTIDES The effect of caffeine on endurance time to exhaustion A new method for autonomous retrieval of a satellite Boron analogues of amino acids and derivatives at high altitude using a visual sensor and a manipulator [ADA2113111 p 36 N90-12157 [ADA2120691 p47 N90-12163 [IAF PAPER 89441] p54 A90-13272 PERCEPTION MUSCULAR STRENGTH OPTICAL ILLUSION Effects of type of responding on memory/visual search Wrist orientation effect on grip strength and The occurrence of the vectbn illusion among heliter Responding just yes or just no can lead to inflexible endurance pilots while flying over water p52 A90-13743 perfOrmanCe [PB89-2009351 p61 N90-12179 OPTOMETRY [ AD-A21 27641 p53 N90-13033 MUSCULOSKELETAL SYSTEM A Scheinerprinciple pocket optometer for PERFORMANCE TESrS Microgravity and musculoskeletal system of mammals self-evaluation and biofeedback accommodation training Pre and posfflight postural control of the Dl Spacelab p25 A90-15052 [ADA2131711 p51 N90-13027 mission astronauts examined with a tilting room The effect of suspension on nicotinic acetylcholine ORBITAL SERVICING [ IZF-1988-253 p63 N90-13039 receptor number and affinity at the rat neuromuscular The Flioht Telerobotic Sewicer NASA's first omrational PHOSPHORIC ACID - Membrane fusion: The role of polyphosphatidyiirmsitol junction p31 A90-15483 space r&t Miogravityinduced changes in human bone strength [IAF PAPER 89-0501 p54 A90-13277 [ADA2112891 p36 N90-12156 p 43 A90-15493 Advancer, in robotics PHOSPHORYLATION space Membrane fusion: The role of polyphosphatidylinositol Skeletal muscle antioxidant enzyme levels in rats after [IAF PAPER 694521 p55 A90-13279 simulated weightlessness. exercise and dobutamine Requirements and concepts for the Space Station [AD-A211289] p38 N90-12156 p 32 A90-15498 Remote Manipulator System PHOTOCHEMICAL REACTIONS Changes of muscle function and size with bedrest [IAF PAPER 890691 p 55 A90-13289 Application of tubular photo-bioreactor system to culture D43 A90-15501 Design guidelines for accommodation of robotic and spirulina for gas exchange and food production in MYOCARDIUM manipulative on Station Freedom CELSS deices Space [IAF PAPER 89-5771 p56 A90-13616 Cellular and molecular mechanisms of high pressure [IAF PAPER 89-0841 p55 A90-13300 PHOTOSENSITIVITY inotrqy in cardiac muscle ORGANIC COMPOUNDS [ADA2116951 p48 N90-12170 Prebiotic organic matter trom comets and asteroids Dorsal liiht response and changes of its responses p64 A90-161M) under varying acceleration conditions --_ in Boldfish p28 A90-15080 ORTHOSTATIC TOLERANCE N The expression of a circadian rhythm in two strains of Orthostatic intolerance post space aihl~ A multitectotial Chlamydomonas reinhardii in space p 29 A90-15083 NAPHTHALENE disordet? [IAF PAPER 89.5951 p 39 A90-13627 PHOTOSYNTHESIS Human body regional convective heat transfer Evidence for anoxygenic photosynthesis from the determination using sublimating naphthalene disks Propranololand the compensatory circulatory responses to orthostasis at high altitude p40 A90-13736 distribution of bactekhlorophylls in the Black Sea [ AD-AZl 21 701 p47 N90-12165 p24 A90-14631 NASA PROGRAMS OTOLITH ORGANS Unilateral centrifugation of the otoliths as a new method Current and potential productivity of wheat for a NASA spinoffs to bioengineering and medicine controlled environment life support system to determine bilateral asymmetries of the otolith apparatus [IAF PAPER 89-6831 p 40 A90-13673 p 57 A90-15427 NASA SPACE PROGRAMS in man [IAF PAPER 89-5661 p37 A90-13609 PHYSICAL EXAMINATIONS Space robot& in the '90s p 57 A90-14998 Effects of body posture on the interpretation of The Life Sciences program at the NASA Ames Research Otolith-spinal reflex testing on Spacelab-1 and D-1 p 43 A90-15495 biomedical data obtained from manned missions Center. An overview p30 A90-15478 [IAF PAPER 89-5961 p39 Am-13828 NEUROYUSCUUR TRANSUISSION Pre- and postflight postural control of the D1 Spacelab mission astronauts examined with a tilting room PHYSICAL EXERCISE The effect of suspension on nicotinic acetylcholine [IZF-1988-25] p 63 N90-13039 Reduced systolic blood pressure elevations during receptor number and affinity at the rat neuromuscular maximum exercise at simulated altitudes junction p31 A90-15483 OXIDATION Subcritical and supercritical water oxidation of CELSS p 40 A90-13738 Anatomical study of the final common pathway for model wastes p 59 A90-15436 Work capacity, exercise responses and body vocalization in the cat p 34 A90-16284 OXYGENCONSUMPTION composition of professional pilots in relation to age Synaptic plasticity and memory formation Oxygen separation system of residential space at the p40 A90-13739 [ADA2113681 p36 N90-12158 lunar base Skeletal muscle antioxidant enzyme levels in rats after NEUROPHYSIOLOGY [IAF PAPER 69-5741 p56 A90-13613 simulated weightlessness, exercise and dobutamine Biochemical conelates of neurosensory changes in Effect of CO2 and 02on development and fructification p32 A90-15498 weightlessness of wheat in closed systems p57 AM-15426 Exertional heatstroke: An international perspective. An [IAF PAPER 89-5981 p 39 A90-13630 Effectsof simulated weightlessnessand sympathectomy introduction:. The role of exercise in the etiology of Neurochemistry of hibernation in mammals --- Russian on maximum VO2 of male rats p32 A90-15491 exertional heatstroke book p 34 A90-16057 The effect of caffeine on endurance time to exhaustion [ AD-A2122421 p50 N90-13020 Anatomical study of the final common pathway for at high altitude PHYSICAL FITNESS vocalization in the cat p34 A90-16284 [ ADA21 20691 p47 N90-12163 Exercise strategies and assessment of cardiorespiratory Synaptic plasticity and memory formation Prediction of thermal stress casuelties fitness in space [AD42113681 p36 N90-12158 [ADA21 23561 p 50 N90-13022 [AAS PAPER 87-2361 p46 A90-16535 NIGHT VISION OXYGEN PRODUCTION Automation of fitness management for extended space Oxvoen sewation svstem of residential soace at the Visual acuity and stereopsis with night vision goggles missions [ADA21 15521 p47 N90-12167 lunar-Case ' [AAS PAPER 87-2391 p46 A90-16538 [IAF PAPER 89-5741 p56 A90-13613 Demonstration of replicable dimensions of health A Scheiner-principle pocket optometer for Awlication of tubular Dhoto-bioreactor svstem to culture self-evaluation and biofeedback accommodation training behaviors spihiina for gas exchange and food. production in [AD-A211920] p46 N90-12161 [ADA2131711 p51 N90-13027 CELSS The effect of concurrent strength and endurance training NITROGEN DIOXIDE [ IAF PAPER 89-5771 p56 A90-13616 on electromechanical delay, maximum voluntary Synergistic effects of nitrogen dioxide and carbon dioxide Closed and continuous algae cultivation system for food following acute inhalation exposures in rats production and gas exchange in CELSS contraction, and rate of force d%velopment [PB89-214779 J p35 N90-12150 p 60 A90-15445 [AD421 33161 p51 N90-13028 NITROGENATION PHYSIOLOGEAL EFFECTS Study on the nitrogen fixation system required for plant Synergistic effects of nitrcgendioxide and carbon dioxide culture in a lunar base P following acute inhalation exposures in rats [IAF PAPER 89-5751 p56 A90-13614 [ PB89-2147791 p35 N90-12150 Carbon cycling by cellulosefemmnting nitrogen-fixing PAIN Effects of atmospheric mix and toxic fumes on military bacteria p 30 A90-15442 Effects of transitjon from supine to upright positions on performance central hemodynamics in patients with chest pain NOISE REDUCTION [ PB69-2236301 p49 N90-13015 syndrome p 43 A90-15490 Application of active noise reduction for hearing Biochemical and physiological changes in glider pilots PARABOLIC FLIGHT protection and speech intelligibility impmvement during multihour riihts [IZF-l988-21 I p 63 N90-13042 Unilateral centnlugation of the otoliths as a new method [ DLR-FB89-291 p49 N90-13018 to determine bilateral asymmetries of the otolith apparatus NUTRITION PHYSIOLOGICAL FACTORS in man Wrist orientation effect on grip strength and A food/nutrient supply plan for lunar base CELSS [IAF PAPER 89-5661 p 37 A90-13609 [IAF PAPER 885791 p56 A90-13618 endurance PARTICLE ACCELERATORS [ PB89-2009351 p61 N90-12179 Biophysical principles of the effects of cosmic rays and radiation from acceleratws --.Russian book. Pre and posfflight postural control of the D1 Spacelab 0 p34 A90-16047 mission astronauts examined with a tilting room PATTERN RECOONITION [IZF-198825] p63 N90-13039 OCEAN SURFACE Eye movements and spatial panem vision PHYSIOLOGICAL RESPONSES The mnenceof the vectbn illusion among helicopter [ADA2116501 p48 N90-12169 Decreased swelling pressure of rat nucleus pulposus pilots while flying over water p 52 A90-13743 PAYLOAD RETRIEVAL (STS) associated with simulated weightlessness OLFACTORY PERCEPTlON A new method for autonomous retrieval of a satellite p31 A90-15485 Synaptic plasticity and memory formation using a visual sensor and s manipulator Nmalisation of bone cellular responses occurs [ADA2113881 p36 N90-12158 [IAF PAPER 89-041 I p54 A90-13272 between 7 and 14 days of simulated weightlessness in OPTICAL COMMUNICATION PAYLOADS rats p31 A90-15486

Three stages and two systems of visual processing Continuing studies of 'CELLS fliiht hardware Plasma stress hormones in resting rats ~ Eighty four [AD-A212670] p 53 N90-13032 p32 A90-15497 day study p32 A90-15489

A-10 SUBJECT INDEX RADIOBIOLOGY

Characteristics of the response of animals belonging PLASMA INTERACTIONS PUBLIC HEALTH to various typological groups to high-frequency and Calcium displacement caused by electromagnetic Demonstration of replicable dimensions of health miaowave electromagnetic radiation p 34 A90-15638 fields behaviors Cardiovascular, renal, electrolyte. and hormonal [ADA21 26901 p50 N90-13023 [AD-A2119201 p46 N90-12161 changes in man during gravitational stress. PLUaS PULMONARY FUNCTIONS weightlessness. and simulated weightlessness: Lower Shape instabilities of plate-like smtures. 1: Effect of increased acceleration on lung expansion in body positive pressure applied by the antigravity suit Experimental observations in heavily cold worked in situ dogs - Prone vs. supine body positions [NASA-TM-t02232] p49 N90-13013 Composites p 33 A90-15500 PHYSIOLOGICAL rrsTs [ADA212251 ] p50 N90-13021 Selective hypergravity stimulation: Its effects on the POSITION (LOCATION) human balance and gait functions - A model to assess, Sound Localbation by Human Observers symposium R in normal gravity conditions, some aspects of the proceedings perlwbations induced on human body by microgravity [ADA2128771 p51 N90-13026 RADARRANGE conditions POSTFLIGHT ANALYSIS Base level management of radio frequency radiation [IAF PAPER ST89-0161 p 40 A90-13729 The time wurse of postfhght simulator sickness protection program Modifications of bone atrophy seen with hindlimb symptoms p40 A90-13735 [ADA2117871 p46 N90-12171 POSTURE suspension by exercise and dobutamine RADIATION DAMAGE Effects of body posture on the interpretation of p31 A90-15487 Effect of ultrahighdose ionizing radiation on the contenl. biomedical obtained from manned missions data of cathecholamine mediators in various regions of the rat Calcium homeostasis in prolonged hypokinesia [IAF PAPER 89-5961 p39 A90-13628 brain p 34 A90-15641 p 43 A90-15492 Age-related changes in human posture control: Motor Radiopotective properties of a Co(lll) biocomplex coordination tests RADIATION DOSAGE p33 A90-15634 [NASA-CR-185855] p61 N90-12178 Galactic cosmic radiation exposure and associated Increasing the radioresistance of mice with ivastimul Cardiovascular. renal, electrolyte, and mal health risks for air canier crewmembers p33 A90-15636 changes in man during gravitational stress. p41 A90-13745 Wrist orientation effect on grip strength and weightlessness, and simulated weightlessness: Lower RADIATION EFFECTS endurance body positive pressure applied by the antigravity suit Accumulation of the biological effects of microwaves [PB89-200935] p61 N90-12179 [NASA-TM-102232] p49 N90-13013 as displayed in the behavior. the physical efficiency. tho PILOT ERROR Pre- and postfliiht postural control of the D1 Spacelab body-mass increase, and the condition of cerebral Fatigue, pilot deviations and time of day mission astronauts examined with a tilting room neurons p33 ~90-1563:7 [ NASACR-1853891 p62 N90-13035 [IZF-t 98&25] p63 N90-13039 Characteristics of the response of animals belonging PILOT PERFORMANCE POTATOES to various typological groups to high-frequency and Recwery to +1Gz and +2Gz following +Gz-induced Utilization of sweet potatoes in controlled ecological life microwave electromagnetic radiation p 34 A90-15638 loss of consciousness - Operational considerations support systems (CELSS) p 58 A90-15429 Effect of ionizing radiation on the binding of muscimol p41 A90-13741 PREDICTION ANALYSIS TECHNIQUES by synaptic membranes of the rat brain The occurrence of the vection illusion among heliter Predicting the postradiative radiosensitivity of mammals p34 Ago-15640 pilots while flying Over water p 52 A90-13743 and man according to the LD50 criterion after acute Biophysical principles of the effects of cosmic rays and Probable bends at 14.000 feet - A case report external irradiation p 34 A90-15639 radiation from accelerators _-- Russian book. p41 A90-13744 PREDICTIONS p 34 A90-16047 Galactic cosmic radiation exposure and associated Studies on predicting the resynchronization of the Investigation of resonant ac& magnetic field effects heaith risks for air carrier crewmembets circadian system after transmedian flights [AD42116121 p 37 N90-12159 [DFVLR-FB89-10] p48 N90-12172 p41 A90-13745 Calcium displacement caused by electromagnetic PROJECT SET1 The spousal factor in pilot stress p 52 A90-13747 fields The NASA SET1 sky survey: Recent developments The effect of occupational work load on the functional [ADA21 26901 p50 N90-13023 state of naval-aviation fliht personnel p 64 N90-12804 RADIATION INJURIES p41 A90-14425 PROPHYLAXIS Pilot performance is increased after alternating hypo- Experimental research on the applicabilities of Chinese Galactic cosmic radiation exposure and associated health risks for air carrier crewmembers and hypergravity states p45 A90-15511 medicine to space medicine Fatigue, pilot deviations and time of day [IAF PAPER 89-601 I p 39 A90-13633 p 41 A90-1374.5 [ NASA-CR-1853691 p62 N90-13035 Prevention of radiation sickness, induced by low-level Biological effects of galactic radiation HZE particles in Spatial tests for aviators ionizing radiation, by repeated injections with increasing experiments on the orbital station Salyut 7 [ IZF-l988-15] p 63 N90-13041 doses of chemical radioprotectors p 33 A90-15633 p28 A90-15057 PILOT TRAINING PROPRIOCEPTION Effects of prolonged exposure of lettuce seeds to HZE The time course of postflight simulator sickness Influence of proprioceptive information on space particles on orbital stations p 26 A90-15058 symptoms p 40 A90-13735 orientation on the ground and in orbiil weightlessness RADIATION PROTECTION A Scheiner-principle pocket optometer for p 42 A90-15079 Radioprotective properties of a Co(lll) biocomplex self-evaluation and biofeedback accommodation training PROTECTIVE CLOTHING p 33 A90-15634 [AD-A213171] p51 N90-13027 Prediction of thermal stress casuabs Radioprotective effects of ATP and ADP on A comparison of two subjectcontrolled attitude [ADA21 23561 p50 N90-13022 membrane-bound enzymes p 33 A90-15635 measures during somatogravic illusion exposure PROTEIN CRYSTAL GROWTH Base level management of radio frequency radiation [ADA2125281 p53 N90-13031 Growth rate study of canavalin single crystals protection program PILOTS (PERSONNEL) p34 A90-16420 l.AD-A211787] p 48 N90-12171 Work capacity. exercise responses and body PROVISIONING Base level management of radio frequency radiation cwnposition of professional pilots in relation to age Air Force flight feeding. Volume 1: Evaluation of current protection program p 40 A90-13739 system and alternative concepts [ADA2117591 p 49 N90-13017 Biochemical and physiologiical changes in glider pilots [ADA2127891 p63 N90-13043 RADIATION SICKNESS during multihour flihts PSYCHOLOQICAL EFFECTS Prevention of radiation sickness, induced by low-level [DLR-FB89-29] p49 N90-13018 Psychologicalmechanisms involved in the disorientation ionizing radiation, by repeated injections with increasing PLANETARY GEOLOQY of pilots due to fliht conditions doses of chemical radioprotectors p 33 A90-15633 3.5 billion years ago: Life on Mars? Hints, indications. [ETN89.95014] p 63 N90-13040 RADIATION TOLERANCE speculations p64 A90-16360 PSYCHOLOGICAL TESTS Increasing the radioresistance of mice with ivastimul PLANT STRESS Microcomputer-based tests for repeated-measures: p33 A90-15636 Cell mechanisms of adaptation to main factors of space Metric properties and predictive validities Predicting the postradiative radiosensitivity of mammals tiiht [NASA-CR-t85517] p52 N90-12174 and man according to the LD50 criterion after acute [IAF PAPER 894061 p23 A90-13634 A menu of self-administered microcomputer-based external irradiation p34 A90-15639 Polarity of root statocytes in space and in simulated neurotoxicology tests RADIO FREQUENCIES microgravity [ NASACR-1855161 p52 N90-12175 Base level management of radio frequency radiation [IAF PAPER 89-6081 p 23 A90-13636 The effect of incentives on the reliability and validity of protection program Productivity and food value of Amaranthw cruentus cognitive tests [ADA2117871 p48 N90-12171 under non-lethal stress p 30 A90-15440 speed salt [ADA2113461 p62 N90-12181 RADIO FREQUENCY HEATING PLANTS (BOTANY) Radio frequency (13.56 MHz) energy enhances PSYCHOMETRICS A study on culturing modules for CELSS in lunar base rewarming from mild hypothermia [IAF PAPER 88-5761 p56 A90-13615 Psydmphysiologiical studiies during the flight of the second Bulgarian cosmonaut [AD-A212703] p 50 N90-13024 Prospects of studies in space phylobiology RADIO WAVES [IAF PAPER 89.5861 p 38 A90-13621 [IAF PAPER 89-5781 p23 A90-13617 Base level management of radio frequency radiation Evaluation of experiments involving the study of plant PSYCHOMOTOR PERFORMANCE protection program orientation and growth under different gravitational Microcomputer-basid tests for repeated-measures: [AD-A211787] p48 N90-12171 conditions p 25 Am15053 Metric properties and predictive valiiis Base level management of radio frequency radiation Plant cell in the process of the adaptation to simulated [NASA-CR-185517] p52 N90-12174 protection program microgravity p 25 A90-15054 A menu of self-administered microcomputer-based [ADA2117591 p 49 N90-13017 Calcium gradient in plant cells with polarized growth in neurotoxiwlogy tests RADIOBIOLOGY simulated microgravity p26 A90-15056 [NASA-CR-165518] p52 N90-12175 Biological effects of galactic radiation HZE particles in Plant cell plasma membrane structure and properties PSYCHOPHYSIOLOGY experiments on the orbital station Salyut 7 under clinostatting p26 A90-15061 Psycho-physiological studies during the tiiht of the p26 A90-15057 Carbon balance and productivity of Lemna gibba. a second Bulgarian cosmonaut Radioprotective properties of a Co(lI1) biocomplex candiite plant for CELSS p58 A90-15430 [IAF PAPER 89.5861 p38 A90-13621 p33 A90-15634

A-1 1 RATIONS SUBJECT INDEX

Accumulation of the biological effects of microwaves REMOTELY PILOTED VEHICLES SEMANTICS as displayed in the behavior. the physical efficiency, the Telerobotic wntrol for teams of semi-autonomous Computer generation of a tutorial dialogue body-mass increase, and the condition of cerebral agents, phase 1 [AD421 19761 p46 N90-12162 neurons p33 A90-15637 [AD-A211648] p62 N90-13037 SENSORIMOTOR PERFORMANCE USSR Space life Sdences Dig6st, Iswe 23 RENAL FUNCTION Age-related changes in human posture control: Motor [NASA-CR-3922(27)-lSSUE-23] p 36 N90-12154 Cardiovascular, renal, electrolyte, and hormonal mdination tests RATIONS changes in man during gravitational stress, [NASACR-l85855] p6l N90-12178 Air Force fliht feeding. Volume 1: Evaluation of cunent weightlessness, and simulated weightlessness: Lower SENSORY DEPRIVATION system and alternative concepts body positive pressure applied by the antigravity suit Effects of simulated weightlessnessand sympathectomy [ADA2127891 p63 N90-13043 [ NASA-TM-1022321 p49 N90-13013 on madmum V02 of male rats p32 A90-15491 REACTOR DESIGN REPRODUCTION (BIOLOGY) SENSORY PERCEPTION Phase separated membrane bioreactor ~ Results from The effect of microgravity on the reproductive function Studies of space adaptation syndrome in experiments model system studies p60 A90-15447 of male rats p31 A90-15488 on primates performed on board of Soviet biosatellite ‘coSmoS-lBB7’ p A90-15494 RECEPTORS (PHYSIOLOGY) RESEARCHPROJECTS 32 Sound Localization by Human Observers symposium The effect of suspension on nicotinic acetylcholine The Life Sciences programat the NASA Ames Research proceedings receptor number and affinity at the rat neuromuscular Center An overview p 30 A90-15478 junction p31 A9015483 - [ADA2128771 p 51 N90-13026 RESOURCE ALLOCATION RECOGNITION A comparison of two subjectcontrolled attitude Electrophysiological studies of visual attention and Synaptic plasticity and memory formation measures during somatogravic illusion exposure [ADA2113681 p 36 N90-12158 resource allocation [AD-AZl 25281 p53 NBO-13031 . [ADA2122871 p53 N90-13030 RECREATION Three stages and two systems of visual processing A zerog CELSSlrecreation facility for an earth/Mars RESPIRATION [ AD-AZl 26701 p 53 N90-13032 crew shuttle Synergistic effects01nitrogendioxideand carbondioxide Spatial tests for aviators [AAS PAPER 87-2351 p6l A90-16534 following acute inhalation exposures in rats [IZF-1988-15] p63 N90-13041 RECYCLING [ PB89-2147791 p35 N90-12150 SICKNESSES Long-term experiments on man’s stay in biological RESPIRATORY SYSTEM The time course of posfflight simulator sickness lie-support system p 58 A90-15433 cardiorespiratory responses to simulated symptoms p 40 A90-13735 Sources and processing of CELSS wastes weightlessness in man p44 A90-15505 SIGNAL DETECTION p59 A90-15435 Exercise strategies and assessment of cardiorespiratory Binaural masking: An analysis of models REDUCED GRAVITY fitness in space [AD-A211578] p48 N90-12168 Importance of the lgcontrols in interpreting the results [AAS PAPER 87-2361 p 46 A90-16535 The NASA SET1 sky survey: Recent developments of an experiment on plant gravitropism (Biorack. D1 REST p 64 N90-12804 mission) Plasma stress hormones in resting rats . Eighty fwr SIGNAL PROCESSING [IAF PAPER 89-6091 p24 A90-13837 day study p 32 A90-15489 Time-frequency factors in auditory perception Life sciences and space research XXlIl(5) - Gravitational RETENTION (PSYCHOLOGY) [AD-AZl 1491] p49 N90-13016 biology: Proceedings of the Topical Meeting and Individual differences in associative learning and SIGNS AND SYMPTOMS Workshops XVll and XVlll 01 the 27th COSPAR Plenary forgetting The time course of postflight simulator sickness Meeting. Espoo. Finland, July 18-29. 1988 [AD421 27651 p54 N90-13034 symptoms p 40 A90-13735 SINGLE CRYSTALS p25 A90-15051 RHYTHM (BIOLOGY] Growth rate study of canavalin single crystals Microgrsvity and musculoskeletal system of mammals Significance of light and social cues in the maintenance p25 A90-15052 of temporal organization in man p 45 A90-15512 p34 ABO-16420 Light microscopic analysis of the gravireceptor in SKY SURVEYS (ASTRONOMY) USSR Space Life Sciences Digest, Issue 22 Xenopus larvae developed in hyposravity The NASA SET1 sky survey: Recent developments p28 A90-15081 [NASA-CR-3922(26)-ISSUE-22] p 35 N90-12153 p64 N90-12804 The biological clock of Neurospora in a microgravity ROBOTICS SOCIOLOGY environment p29 A90-15082 The Flight Telerobotic SeMcec. NASA’s first operational Significance of liht and social cues in the maintenance Rhythmic biological systems under microg conditions space robot of temporal organization in man p 45 A90-15512 p 29 A90-15084 [IAF PAPER 89-0501 p54 A90-13277 SOUND LOCALIZATION Gas bubble coalescence in reduced gravity conditions Development of the 2nd generation space robot in Sound Localization by Human Observers symposium p30 A90-15446 NASDA proceedings Changes in kidney response to ADH under hypogravity [ IAF PAPER 89-051] p54 A90-13276 [AD-A212877] p51 N90-13026 - Rat models and possible mechanisms Advances in space robotics SOUND TRANSMISSION p30 A90-15482 [IAF PAPER 89-0521 p55 A90-13279 Sound Localization by Human Observers symposium Microgravity-inducedchanges in human bone strength Design guidelines for accommodation of robotic and proceedings p43 A90-15493 manipulative devices on Space Station Freedom [ AD-A2128771 p 51 N90-13026 I REFLEXES [IAF PAPER 89-0841 p 55 A90-13300 SPACE ADAPTATION SYNDROME Otolith-spinal reflex testing on Spacelab-1 and 0-1 Space robotics in the ’90s p57 A90-14998 The next 40 years in space - Aspects of human factors p43 A90-15495 Robotics and teleoperation p60 A90-16352 in space research REGENERATION (ENGINEERING) Three dimensional object recognition employing [IAF PAPER 89-091I p 37 A90-13304 Waste recycling issues in boregeneratie lie support combined visual and tactile sensing A report of ground results for brain function experiments p 59 A90-15434 [ PB89-2194891 p52 N90-12176 in space RELIABILITY Telerobotic control for teams of semi-autonomous [IAF PAPER 89-5901 p 38 A90-13624 The effect of incentives on the reliability and validity of agents, phase 1 cognitive speed tests Biochemical correlates of neurosensory changes in I [AD-A211648] p 62 N90-13037 weightlessness [ADA2113461 p62 N90-12181 ROBOTS RELIABILITY ENGINEERIN6 [IAF PAPER 89-5981 p 39 A90-13630 West Germany’s first space robot p 57 A90-14999 Experimental research on the applicabilities of Chinese Telerobotic wntrol for teams of semi-autonomous Teleoperators p60 A90-15800 agents, phase 1 medicine to space medicine RODENTS [IAF PAPER 89801] p39 A90-13633 [ADA2116481 p62 N90-13037 The rodent research animal holding facility as a barrier REMOTE CONTROL to environmental contamination Yaw sensory rearrangement changes pitch responses Telescience testbed for physblogical experiments [NASA-TM-102237] p 35 N90-12151 --in human head movement and ocular response [IAF PAPER ST49-0121 p40 A90-13727 [IAF PAPER 89-0341 p 37 A90-13267 ROOTS Modular ABR system testbed for development and Polarity of root statocytes in space and in simulated Influence of proprioceptive information on space implementationof automationand robotics elements within microgravity orientation on the ground and in orbital weightlessness future &ita1 systems [IAF PAPER 89-6081 p23 A90-13636 p 42 A90-15079 Studiis of space adaptation syndrome in experiments I [IAF PAPER 89-0361 p54 A90-13269 REMOTE HANDLING on primates performed on board of Soviet biosatellite Teleoperators p 60 A90-15800 S ‘Cosmos-1887’ p 32 A90-15494 REMOTE MANIPULATOR SYSTEM Life beyond gravity p45 A90-16299 SAFETY FACTORS A new method for autonomous retrieval of a satellite Wwk on human adaptation to long-term space flight in Teleoperators p60 A90-15800 using a visual sensor and a manipulator UK SALINITY the [IAF PAPER 89441I p54 A90-13272 [AAS PAPER 87-2371 p46 A90-16536 Productivity and food value of Amaranthus mntus first Space physiology and medicine (2nd edition) Book me Fliiht Telerobotic Sewicer - NASA‘s operational under non-lethal salt stress p 30 A90-15440 --_ space robot SALYUT SPACE STATION p46 A90-16625 [IAF PAPER 890501 p54 A90-13277 Biological effects of galactic radiation HZE particles in Cardiovascular, renal, electrolyte, and hormonal Develcpment of the 2nd generation space robot in experiments on the orbital station Salyut 7 changes in man during gravitational stress. NASDA p26 A90-15057 weightlessness, and simulated weightlessness: Lower [IAF PAPER 89-0511 p 54 A9013278 SEARCHING body positive pressure applied by the antigravity suit Requirements and concepts for the Space Station Effects of type of responding on memocylvisualsearch: [NASA-TM-1022321 p49 N90-13013 Remote Manipulator System Responding just yes or just no can lead to inflexible SPACE COLONIES [IAF PAPER 89-0691 p 55 A90-13289 performance Oxygen separation system of residential space at the Design and evaluation of man-in-the-loopcontrol system [ADA21 27641 p53 N90-13033 lunar base of Japanese Experimental Module Remote Manipulator SEEDS [ IAF PAPER 89-5741 p56 A90-13613 System Effects of prolonged exposure of lettuce seeds to HZE Utilition of white potatoes in CELSS [IAF PAPER 89-0901 p55 A90-13303 particles on orbiil stations p 26 A90-15058 p58 A90-15431

A-12 SUBJECT INDEX SYNAPSES

Considerations for the living areas within space Proposal for a zero-gravity toilet facility for the space SPACECRAFT ENVIRONMENTS settlements station Active vibration control for flexible space environment [AAS PAPER 87-2421 p61 A90-16541 [NASA-CR-183151] p62 N90-13036 use manipulators p 60 A90-16522 SPACE ENVIRONMENT SIMULATION SPACE SUITS Individual differences. mission parameters, and I Calcium homeostasis in prolonged hypokinesia Simulation by personal workstation for Man-Machine spaceflight environment habitability I p 43 A90-15492 Interface design [AAS PAPER 87-2401 p61 A90-16539 SPACE FLIGHT STRESS [IAF PAPER 89-0891 p 55 A90-13302 SPACECRAFT MODULES Biomedical payload of the French-Soviet long duration SPACE TOOLS Studies on Habitation Module and interconnecting fliht - First conclusions Modular ABR system testbed for development and elements for a future European space station 1 implementationof automationand robotics elements within [IAF PAPER 89-5633 p37 A90-13606 [IAF PAPER 89-0921 p 55 A90-13305 Effect of space flihts and hypokinesiaon plasma insulin future orbital systems A zero-g CELSS/recreation facility for an earthlMani [IAF PAPER 89-0361 p A90-13269 1 levels and insulin receptors in rat liver 54 crew shuttle [IAF PAPER 89-5641 p23 AM-13607 The Flight Telarobotic Servicer - NASA's first operational [AAS PAPER 87-2351 p 61 A90-16534 space robot Medical results of the flight of the second prime crew SPACECREWS on the orbital station Mir [IAF PAPER 89-0501 p 54 A90-13277 Development of the 2nd generation space robot in Space Station Freedom crew training ! [IAF PAPER 89-5941 p38 A90-13626 [IAF PAPER 89-0981 p 51 A90-133013 I Orthostatic intolerance post space fliht - A multifactorial NASDA 1 diswder? [IAF PAPER 89-051 I p 54 A90-13278 The basic health care system for the crew lunar base [IAF PAPER 89-5951 p39 AW-13627 Advances in space robotics [IAF PAPER 89-5731 p 38 A90-13612 Medical results of the flight of the second prime crew I Cell mechanisms of adaptation to main factors of space [IAF PAPER 89-0521 p55 A90-13279 flight Space robotics in the '90s p57 A90-14998 on the orbital station Mir [IAF PAPER 89-6081 p23 A90-13634 West Germany's first space robot p 57 A90-14999 [IAF PAPER 89-5941 p 38 A90-13626 Study of activation of human peripheral blood Robotics and taleoperatin p60 A90-16352 SPACELAB mononuclear cells after a space flight SPACEBORNE EXPERIMENTS Otolith-spinal reflex testing on Spacelab-1 and D-1 [IAF PAPER 89-611 ] p24 A90-13639 Telescience testbed for physiological experiments p43 A90-15495 Ultrastructural and growth indices of Chlorella culture [IAF PAPER 89-0341 p37 A90-13267 Pre- and postflight postural control of the D1 Spacelab in multicomponent aquatic systems under space flight Modular ABR system testbed for development and mission astronauts examined with a tilting rmm conditions p27 A90-15063 implementationof automationand robotics elements within [IZF-1988-25] p 63 N90-13039 International Union of Physiological Sciences future orbital systems SPACELABPAYLOADS Commission on Gravitational Physiology, Annual Meeting, [IAF PAPER 89-0361 p 54 A90-13269 Polarity of root statocytes in space and in simulated 10th. Montreal, Canada, Oct. 9-14. 1988. Proceedings Biomedical Dadoad of the French-Soviet low duration microgravity p42 A90-15477 fliht - First conilusions [ IAF PAPER 89-6081 p 23 A90-13636 Periodic acceleration stimulation in a weightlessness [IAF PAPER 89-5631 p37 A90-13606 Gravitational biology within the German microgravity environment (PASWE) - A new science? Effect of wace flights and hmkinesia on .Dlasma insulin program - Current status and further pursuits p 30 A90-15479 levels and insulin receptors in'rat liver IIAF PAPER 89-6121 p24 A90-13640 The effect of microgravity on the reproductive function [IAF PAPER 89-5641 p23 A90-13607 Psycho-physiological studies during the flight of the Developmental biology in space - Why and how7 of male rats p31 A90-15486 p 27 A90-15070 Changes of muscle function and size with bedrest second Bulgarian cosmonaut p43 A90-15501 [ IAF PAPER 89-5661 p38 A90-13621 SPATIAL DISTRIBUTION Automation of fitness management for extended space A report of ground results for brain function experiments Visual motion perception [ADA2109941 p48 N90-12160 I missions in space [AAS PAPER 87-2391 p46 A90-16538 [IAF PAPER 89-5901 p 38 A90-13624 Eye movements and spatial pattern vision SPACE FLIGHT TRAINING Response of unicellular organisms to the contiions in [ADA2116501 p46 N90-12169 Space Station Freedom crew training low earth orbit SPECTRUM ANALYSIS [IAF PAPER 89-0981 p51 A90-13308 [IAF PAPER 89-6101 p 24 A90-13838 The NASA SET1 sky survey: Recent developments SPACE HABITATS Gravitational biology within the German microgravity p64 N90-12804

Studies on Habitation Module and interconnecting program ~ Currant status and further pursuits SPEECH RECOGNITION elements for a future European space station [IAF PAPER 89-6121 p24 A90-13640 Shape instabilities of plate-like structures. 1: [IAF PAPER 894921 p55 A90-13305 Miiogravity and musculoskeletal system of mammals Experimental ObseNationS in heavily cold worked in situ SPACE MAINTENANCE p 25 A90-15052 composites A new method for autonomous retrieval of a satellite Evaluation of experiments involving the study of plant [ADA212251 ] p50 N90-13021 using a visual sensor and a manipulator orientation and growth under different gravitational Application of active noise reduction for hearing I [IAF PAPER 89-0411 p54 A90-13272 conditions p 25 Ago-1 5053 protection and speech intelligibility improvement SPACE PERCEPTION Formation and growth of callus tissue of Arabidopsis [IZF-1988-21] p63 N90-13042 I Binocular depth perception and its hyperacuity in under changed gravity p 25 A90-15055 SPINE 1 common and specialiy selected subjects Effects of prolonged exposure of lettuce seeds to HZE Decreased swelling pressure of rat nucleus pulposus [IAF PAPER 89-5881 p38 A90-13622 particles on orbital stations p26 A90-15058 associated with simulated weightlessness Influence of proprioceptive information on space Experiment on 'Discovery' STS 51-C - Aggregation of p 31 A90-15485 orientation on the ground and in orbital weightlessness red cells and thrombocytes in heart disease, STATISTICAL ANALYSIS p 42 A90-15079 hyperlipidaemiaand other conditions p 42 A90-15060 Visual acuity, and stereopsis with night vision goggles Visual motion perception Potential sites for the perception of gravity in the acellular IAD-A2115521 0 47 N90-12167 [AD42109941 p46 N90-12160 slime mold Physarum polycephalum p 26 A90-15062 STRESS (PHYS~OLOGV) Visual acuity and stereopsis with night vision goggles Thin film bioreactors in space p 27 A90-15068 The spousal factor in pilot stress p 52 A90-13747 [AD-A211552] p47 N90-12167 Fertilization of frog eggs on a sounding rocket in Heatstroke pathophysiology: The energy depletion Disniminating rigii from nonrigid motion space p 28 A90-15076 model [ADA2117941 p62 N90-12180 The biological clock of Neurospora in a microgravity [ADA2121561 p47 N90-12164 SPACE PROCESSING environment p 29 A90-15082 Microcomputer-based tests for repeated-measures: Utilization of whiie potatoes in CELSS The expression of a circadian rhythm in two strains of Metric properties and predictive validities p58 A90-15431 Chlamydomonas reinhardii in space p 29 A90-15083 [NASA-CR-185517] p52 N90-12174 The case for cellulose production on Mars Gravitational biology and the mammalian circadian A menu of self-administered microcomputer-based [AAS PAPER 67-2321 p60 A90-16531 timing system p 29 A90-15085 neurotoxicology tests SPACE PSYCHOLOGY Biochemical and histochemical obwations of vastus [NASA-CR-185518] p52 N90-12175 Individual diierences. mission parameters, and medialis from rats flown in Cosmos 1867 (experiment Prediction of thermal stress casualties I spaceflight environment habitability K608) p 31 A90-15484 [ AD-A2123561 p 50 N90-13022 [AAS PAPER 87-2401 p61 A90-16539 Studies of space adaptation syndrome in experiments Effects of serial wetdry-wet cold exposure: Thermal SPACE STATION PAYLOADS on primates performed on board of Soviet biosatellite balance. physical activity, and cognitive performance Using computer graphics to design Space Station 'Cosmos-1887' 032 A90-15494 [ADA2127041 p5t N90-13025 Freedom viewing Otolih-spinal reflex testing on Spacelab-l and D1 STUDENTS [IAF PAPER 89-0931 p56 A90-13306 p 43 A90-15495 Computer generation of a tutorial dialoguep46 N90-12162 SPACE STATION STRUCTURES Continuing studies of 'CELLS flight hardware [AD-A2119761 I Design guidelines for accommodation of robotic and p 32 A90-15497 SUBLIMATloN manipulative devices on Space Station Freedom Human body regional convective heat transfer [IAF PAPER 69-0841 p55 A90-13300 spaceStation accommodation Of liesciences in determination using sublimating naphthalene disks SPACE STATIONS of a manned Mars mission [ADA21 21701 p 47 N90-12165 [AAS PAPER 87-2331 Requirements and concepts for the Space Station 35 A90-16532 SURFACE REACTIONS Remote Manipulator System Work on human adaptation to long-term space fliht in Synaptic plasticity and memory formation [IAF PAPER 894691 p55 A90-13289 the UK [AD-A211368] p36 N90-12158 Human factors and productivity on Space Station [AAS PAPER 87-2371 p 46 A90-16536 SYMPATHETIC NERVOUS SYSTEM Freedom SPACECRAFT CONTAMINATION Effects of simulatedweightlessness and sympathectomy [IAF PAPER 894871 p55 A90-13301 The rodent research animal holding facili as a barrier on maximum V02 of male rats p32 A90-15491 Studies on Habitation Module and interconnecting to environmental contamination SYNAPSES elements for a Mure European space station [NASA-TM-l02237] p35 N90-12151 Synaptic plasticity and memory formation [IAF PAPER 890921 p55 A90-13305 SPACECRAFT DESIGN [ADA21 13681 p36 N90-12158 Space Station accommodationof liesciences in support Using computer graphics to design Space Station Fear-potentiatedstartle as a model System for analyzing of a manned Mars mission Freedom viewing learning and memory [AAS PAPER 87-2331 p35 A90-16532 [IAF PAPER 89-0931 p 56 A90-13306 [AD42121311 p53 N90-13029

A-13 SYNCHRONISM SUBJECT INDEX

SYNCHRONISM TOILETS VESTIBULAR TESTS Studies on predicting the resynchronization of the Proposal for a zerogravity toilet facility for the space Yaw sensory rearrangement changes pitch responses circadian system after transmedian flights station --_ in human head movement and ocular response [DFVLR-FB-89-t01 p48 N90-12172 [NASA-CR-1831 51 I p62 N90-13036 [IAF PAPER ST49-0121 p40 A90-13727 SYNTAX TOLERANCES (PHYSIOLOGY) VESTIBULES Computer generation of a Moria1 dialogue Effects of serial wetdry-wet cold exposure: Thermal Dorsal light response and changes of its responses [AD-A211976] p46 N90-12162 balance, physical activity. and cognitive performance under varying acceleration contiions --- in goldfish SYNTHESIS (CHEMISTRY) [ AD-A2127041 p 51 N90-13025 p 28 A90-15080 Boron analogues of amino acids and derivatives TOUCH Studies of space adaptation syndrome in experiments [AD-A211311] p 36 N90-12157 Three dimensional object recognition employing on primates performed on board of Soviet biosatellite SYSTEMS ENGINEERING combined visual and tactile sensing 'Cosmos-1887' p32 A90-15494 Requirements and concepts for the Space Station [PB89-2194891 p52 N90-12176 VIBRATION DAMPING Remote Manipulator System TOXIC HAZARDS Active vibration control for flexible space environment [ IAF PAPER 894691 p55 A90-13289 Advances in combustion toxicology. Volumes 1 8 2 --- use manipulators p 60 A90-16522 Design guidelines for accommodation of robotic and Book p24 A90-13903 VIDEO EQUIPMENT manipulative devices on Space Station Freedom [IAF PAPER 89-0841 p 55 A90-13300 TOXICITY Three dimensional object recognition employing Effects of atmospheric mix and toxic fumes on military combined visual and tactile sensing SYSTOLIC PRESSURE performance [PB89-219489] p52 N90-12176 Reduced systolic blood pressure elevations during maximum exercise at simulated,altitudes [ PB89-2236303 p 49 N90-13015 VIEWING p 40 A90-13738 TOXICOLOGY Using computer graphics to design Space Station Advances in combustion toxicology. Volumes 1 8 2 -_ Freedom viewing Book p 24 A90-13903 [IAF PAPER 89-0931 p56 A90-13306 T Microcomputer-based tests for repeated-measures: VIKING MARS PROGRAM Metric properties and predictive validities 3.5 billion years ago: Life on Mars? Hints, indications, TARGETS [ NASA-CR-1855171 p 52 N90-12174 speculations p64 A90-16360 The time required for US. Navy fighter pilots to shift A menu of self-administered microcomputer-based VISION gaze and identify near and far targets neurotoxicology tests Fear-potentiatedstartle as a model system for analyring p41 A90-13740 [NASA-CR-1855181 p 52 N90-12175 learning and memory Visual acuity and stereopsis with night vision goggles TRANSFERRING [AD-A212131] p 53 N90-13029 [AD-A211552] p47 N90-12167 Effects of type of responding on memorylvisualsearch Three stages and two systems of visual processing I TECHNOLOGICAL FORECASTING Responding just yes or just no can lead to inflexible [ADA2126701 p53 N90-13032 Space robotics in the '90s p57 A90-14998 performance VISUAL ACUITY TECHNOLOGY ASSESSMENT [ AD-A2127641 p53 N90-13033 Binocular depth perception and its hyperacuity in The role of computerized modeling and simulation in TRANSPIRATION common and specially selected subjects the development of lie support system technologies Transpiration during life cycle in controlled wheat [IAF PAPER 89-5881 p 38 A90-13622 p 59 A90-15439 growth p 58 A90-15432 Visual acuity and stereopsis with night vision goggles TELEOPERATORS TREES (MATHEMATICS) [AD-A2115521 p 47 N90-12187

The Flight Telerobotic Senricer ~ NASA's first operational Three dimensional obit recognition employing Discriminating rigid from nonrigid motion space robot combined visual and tactile sensing [AD-A21 17941 p 62 N90-12180 I [IAF PAPER 89-0501 p54 ASO-13277 [PB89-219489] p52 N90-12176 A Scheiner-principle pocket optometer for Advances in space robotics TROPICAL REGIONS self-evaluation and biofeedback accommodation training [IAF PAPER 89-0521 p55 Am13279 The effect of occupational work load on the functional [AD-A213171] p 51 N90-13027 West Germany's first space robot p 57 A90-14999 state of naval-aviation flight personnel VISUAL DISCRIMINATION Teleoperators p 60 A90-15800 p 41 A90-14425 Three dimensional object recognition employing Robotics and teleoperation p60 A90-16352 combined visual and tactile sensing Telerobotic control for teams of semi-autonomous [PB89-219489] p52 N90-12176 agents, phase 1 U Discriminating rigid from nonrigid motion [ADA21 16481 p62 N90-13037 [AD-A2117941 p62 N90-12180 U.S.S.R. TEMPERATURE EFFECTS VISUAL FIELDS USSR Space Life Sciences Digest, Issue 22 Spatial tests for aviators Heat exhaustion [NASACR-3922(26)-lSSUE~ZZ] p 35 N90-12153 [ AD-A2121 281 p49 N90-13014 [IZF-l988-15] p 63 N90-13041 USSR Space Life Sciences Digest, Issue 23 VISUAL PERCEPTION TEST EQUIPMENT [NASA-CR-3922(27)-lSSUE.23] p 36 N90-12154 Modular A8R system testbed for development and Unilateral centrifugation of the otoliths as a new method implementationof automationand robotics elements within U.S.S.R. SPACE PROGRAM to determine bilateral asymmetries of the otolith apparatus future orbital systems USSR Space Life Sciences Digest. Issue 24 in man [IAF PAPER 89-0361 p 54 A90-13269 [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 [IAF PAPER 89-5661 p37 A90-13609 USER REQUIREMENTS THERAPY Visual motion perception Radio frequency (13.56 MHz) energy enhances State of the art of humadmachine dialog tool [AD42109941 p48 N90-12160 rewarming from mild hypothermia prototypes Visual acuity and stereopsis with night vision goggles [TELECOM-PARIS-89-HOOl] p 62 N90-13038 [ AD42127031 p50 N90-13024 [AD-A211552] p47 N90-12167 THERMAL COMFORT Eye movements and spatial pattern vision Head cooling is desirable but not essential for preventing V [ AD-A21 16501 p 48 N90-12169 heat strain in pilots p57 A90-13737 Electrophysiological studies of visual attention and THERMAL PROTECTION VASOCONSTRICTOR DRUGS resource allocation Effects of serial wetdry-wet cold exposure: Thermal Hemodynamics during head down tilting and lower body [AD-A212287] p53 N90-13030 balance, physical activity. and cognitive performance negative pressure and pharmacological interventions for Pre- and postflight postural control of the D1 Spacelab [ AD-A2127041 p 51 N90-13025 wuntermeasures mission astronauts examined with a tilting room THERMAL STRESSES [ IAF PAPER 89-5971 p 39 A90-13629 [IZF-l988-25] p 63 N90-13039 I Prediction of thermal stress casualties VEGETATION GROWTH VISUAL STIMULI [ADA2123561 p50 N90-13022 Prospects of studies in space phyiobiology Visual motion perception THERMOREGULATION [IAF PAPER 89-5781 p 23 A90-13617 [AD-A210994] p46 N90-12160 Temperature regulation in rats exposed to a 2 G field VEINS Electrophysiological studies of visual attention and , p 32 A90-15499 Hemodynamics of leg veins during a days bed rest resource allocation I THIN FILMS 30 . Effect of lower body negative pressure (LBNP) [AD-A212287] p 53 N90-13030 Thin film bioreactors in space p 27 A90-15068 p45 A90-15508 Three stages and two systems of visual processing THROMBOCYTES VERTICAL ORIENTATION [AD42126701 p53 N90-13032 Experiment on 'Discovery' STS 51C. Aggregation of A comparison of two subjectcontrolled attitude Effects of type of responding on memory/visual search red cells and thrombocytes in heart disease, measures during somatogravic illusion exposure Responding just yes or just no can lead to inflexible I hyperlipidaemia and other conditions p 42 A90-15060 [ADA212528] p53 N90-13031 performance ' THROMBOSIS VERTlCAL PERCEPTION [ ADA21 27641 p53 N90-13033 Deep venous thrombosis in the military pilot Selective hypergravity stimulation: Its effects on the VISUAL TASKS p 41 A90-13742 human balance and gait functions - A model to assess, The time required for US. Navy fighter pilots to shift TIME in normal gravity wndins, some aspects of the gaze and identify near and far targets Time-frequency factors in auditory perception perturbations induced on human body by microgravity p41 A90-13740 [ AD-AZl 1491] p49 N90-13016 contiions Spatial tests for aviators I Fatigue, pilot deviations and time of day [IAF PAPER ST49-0161 p40 A90-13729 [IZF-1988-15] p63 N90-13041 [NASA-CR-185369] p62 N90-13035 Dorsal light response and changes of its responses VOICE TISSUES (BIOLOGY) under varying acceleration contiions --- in goldfish Anatomical study of the final common pathway for Membrane fusion: The role of polyphosphatidylinositol p 28 A90-15080 vocalization in the cat p 34 A90-16284 [AD-A211289] p36 N90-12156 VESTIBULAR NYSTAGMUS VOMITING Investigation of resonant acdc magnetic field effects Influence of gravitoinertialforce on vestibular nystagmus 8-OH-DPAT suppresses vomiting in the cat elicited by [ADA2116t2] p37 N90-12159 in man observed in a centrifuge p 42 A90-15078 motion. cisplatin or xylazine p 34 A90-16286 ~

SUBJECT INDEX YAWING MOMENTS

W Carotid baroreflex response following 30 days exposure to simulated microgravity p44 A90-15502 WARNING SYSTEMS Cardiorespiratory responses to simulated Shape instabilities of plate-like sbuctures. 1: weightlessness in man p44 A90-15505 Experimental observations in heavily cold worked in situ Cardiovascular, renal, electrolyte, and hormonal com po s it e s changes in man during gravitational stress. [ADA212251 ] p 50 N90-13021 weightlessness, and simulated weightlessness: Lower WASTE DISPOSAL body poskive pressure applied by the antigravity suit Proposal for a zerogravity toilet facility for the space [NASA-TM-1022321 p49 N90-13013 station WHEAT [NASA-CR-183151] p62 N90-13036 Current and potential productivity of wheat for a WASTE TREATMENT controlled environment life support system Life sciences and space research XXlll(3): Natural and p 57 A90-15427 artifiil ecosystems; Proceedings of the Topical Meetings Effect of CO2 and 02 on development and fructification of the 27th COSPAR Plenary Meeting. Espoo. Finland, of wheat in closed systems p 57 A90-15428 July 18-29. 1988 p 57 A90-15426 Transpiration during life cycle in controlled wheat Waste recycling issues in bioregenerative life support growth p 58 A90-15432 p 59 A90-15434 WORK CAPACITY Sources and processing of CELSS wastes Work capacity, exercise responses and body p59 A90-15435 composition of professional pilots in relation to age Subcritical and supercritical water oxidation of CELSS p40 Am-13739 model wastes p59 A90-15436 WORKLOADS (PSYCHOPHYSIOLOGY) WATER CONSUMPTION The effects of automation on work in space increasing central blood volume with head-down tilting [IAF PAPER 69-5831 p57 A90-13620 would inhibit water intake during mild pedaling at 25 C The effect of occupational work load on the functional and 35 C room temperatures in woman state of naval-aviation flight personnel p45 A90-15510 p41 A90-14425 WATER IMMERSION WORKSTATIONS Effects of serial wetdry-wet cold exposure: Thermal Simulation by personal workstation for Man-Machine balance, physical activity, and cognitive performance Interface design [ADA2127041 p51 N90-13025 [IAF PAPER 89-0691 p55 A90-13302 WEIGHTLESSNESS WRIST Long-term exposure to zerog and the gastro-intestinal Wrist orientation effect on grip strength and tract function endurance [IAF PAPER 89-5691 p37 A90-13610 [PB89-200935] p 61 N90-12179 Biochemical correlates of neurosensory changes in weightlessness [IAF PAPER 69-5981 p39 A90-13630 Y Cell mechanisms of adaptation to main factors of space flight YAWING MOMENTS Yaw sensory reanangement changes pitch responses [IAF PAPER 69-6MI p 23 A90-13634 Influence of proprioceptive information on space --- in human head movement end ocular response orientation on the ground and in orbital weightlessness [IAF PAPER ST49-0121 p40 A90-13727 p42 A90-15079 International Union of Physiological Sciences Commission on Gravitational Physiology, Annual Meeting. 10th. Montreal, Canada, Oct. 9-14, l9W. Proceedings p42 A90-15477 Periodic acceleration stimulation in a weightlessness environment (PASWE) - A new science? p30 A90-15479 The effect of suspension on nicotinic acetylcholine receptor number and affinity at the rat neuromuscular junction p31 A90-15483 Biochemical and histochemical observations of vastus medialis from rats flown in Cosmos 1687 (experiment KW) p31 A90-15484 Decreased swelling pressure of rat nucleus pulposus associated with simulated weightlessness p31 A90-15485 Normalisation of bone cellular responses occurs between 7 and 14 days of simulated weightlessness in rats p 31 A90-15466 The effect of microgravity on the reproductive function of male rats p31 A90-15466 Central venous pressure in humans during short periods of weightlessness p 44 A90-15504 A zerog CELSSlrecreation facility for an earthMars crew shuttle [AAS PAPER 87-2351 p61 A90-16534 Cardiwascular. renal, electrolyte, and hormonal changes in man during gravitational stress. weightlessness, and simulated weightlessness: Lower body positive pressure applied by me antigravity suit [NASA-TM-102232] p49 N90-13013 WEIGHTLESSNESS SIMULATION Changes in circadian rhythm of multiple hormones and their relationship with individual susceptibility in simulated weightlessness [IAF PAPER 685651 p37 A90-13606 Plant cultural system incorporated into CELSS [IAF PAPER 89-5801 p57 AM-13619 Plant cell in the process of the adaptation to simulated microgravity p25 AW-15054 Calcium gradient in plant calls with polarized growth in simulated microgravity p26 A90-15056 Potential sites forthe perception of gravity in the acellular Slime mold PhysaNm polycephalum p 26 A90-15062 Effectsof simulatedweightlessness and sympathectomy on maximum VO2 of male rats p 32 A90-15491 Immunocompetent cells producing humoral mediators of bone tissue mineral metabolism during space flight simulation p 43 A90-15496 Skeletal muscle antioxidant enzyme levels in rats after simulated weightlessness. exercise and dobutamine p32 A90-15498

A-15 PERSONAL AUTHOR INDEX

AEROSPACE MEDICINE AND BIOLOGY /A Continuing Bibliography (Supplement 334) March 1990

Typical Personal Author Index Listing ALPATOV, A. N. BARTONICKOVA, A. Plant cell plasma membrane structure and properties Increasing the radioresistance of mice with ivastimul under clinostaiiing p26 A90-15061 p33 A90-15636 PERSONAL AUTHOR ANAVI, SEUM BEAULIEU. S. M. The role of computerized modeling and simulation in Effects of simulatedweightlessness and sympathectomy the development of lie support system technologies on maximum VO2 of male rats p 32 A90-15491 p59 A90-15439 EECKERS, E. 5-GARLAND, JAY L. The next 40 years in space - Aspects of human factors ANDERS, EDWARD A simple, mass balance model of carbon flow in a Prebiotic organic matter from comets and asteroids in space research ecological life support system p64 A90-18160 [IAF PAPER 89091] p 37 A90-13304 [NASA-TM-102151] ANDRE, M. BELLBARBARA Effect of CO2 and 02 on development and fructification systemAir Force and flightalternative feeding. concepts Volume 1: Evaluationp63 NW-13043I of current 7 of wheat in closed systems p 57 A90-15428 r [ADA2127891 ANTONOVA, S. V. BELL, D. Q. Effect of ultrahighdose ionizing radiation the mtent on Theeffect of concurrent strength andendurance training of cathecholamine mediators in various regions of the rat electromechanical delay, maximum voluntary brain p34 A90-15641 on contraction, and rate of force development ARBEILLE, P. [ADA2133161 p51 N90-13028 Effect on the cardiac function of repeated LBNP during BENIQNUS, VERNON A. Listings in this index are arranged alphabetically a one month head down tilt Effects of atmospheric mix and toxic fumes on military [IAF PAPER 89-5931 p 38 A90-13625 by personal author. The title of the document pro- performance ARBEILLE, PH. vides the user with a brief description of the subject [PB89-223630] p49 N90-13015 Plasma ANF comntrations during headdown bed rest BENNElT, SUSAN M. matter. The report number helps to indicate the of various duration (from several hours to one month) - Utilization of white potatoes in CELSS type of document listed (e.g., NASA report, trans- Role of LBNP countermeasure p 44 A90-15503 p58 A90-15431 lation, NASA contractor report). The page and ac- AREND, UWRENCE E. BERBAUM, KEVIN S. Eye movements and spatial pattern vision The time course of postflight simulator sickness cession numbers are located beneath and to the [AD-A211650] p48 N90-12169 symptoms p40 A90713735 right of the title. Under any one author's name the ARMSTRONQ, LAWRENCE E. BERENDSEN, W. accession numbers are arranged in sequence with Heat exhaustion Fertilization of frog eggs on a sounding rocket in the AlAA accession numbers appearing first. [ADA2121281 P49 N90-13014 spa- p 28 A90-15076 AVETISOV, Q. M. BERQWEILER, P. Predicting the postradiative radiosensitivityof mammals Gravitational biology within the German microgravity and man according to the LD50 criterion after acute program - Current status and further pursuits A external irradiation p34 A90-15639 [IAF PAPER 89-6121 p 24 A90-13640 UUMA, SHINSUKE BERIDZE, M. Q. ACKERMAN, PHILLIP L A new method for autonomous retrieval of a satellite Radioprotective effects of ATP and ADP on Effects of type of responding on memory/visual search using a visual sensor and a manipulator membraneboundenzymes p 33 A90-15635 Responding just yes or just no can lead to inflexible [IAF PAPER 89-041] p54 A90-13272 BERKE, SAMUEL performam Geotropic sen- of hwnets p 27 A90-15072 [AD-A212764] p53 N90-13033 BERTHIER, S. AHLERS, S. 1. B Simulation by personal workstation for Man-Machine Effects of serial wetdry-wet cold exposure: Thermal Interface design balance, physical activity, and cognitivepmlormance BABAEV, B. M. [IAF PAPER 894891 055 Am-13302 [ADA21 27041 p51 N90-13025 Studies of space adaptation syndrome in experiments BESCH, STEPHEN R. AIQA, 1. on primates perlormed on board of Soviet biosatellite Cellular and molecular mechanisms of high pressure Plant cultural system incorpOrated into CELSS 'CQSmO51887' p 32 A90-15494 inotropy in cardiac muscle BAIKOVA, 0. V. [IAF PAPER 89-5801 p57 A90-13619 [ADA2116951 p48 N90-12170 The effect of microgravity on the reproductbe function BETTER, H. AKBAROV, B. A. of male rats p31 A90-15488 Otolith-spinal reflex testing on Spacelabt and D-1 Radioprotective properties of a Co(lll) biocomplex BAISCH, F. p 43 A90-15405 p 33 A90-15634 Fluid distribution pattern induced by intravenous fluid BIRD, JULIO J. AKOEV, 1. (i. loading during HDT Effects of transition from supine to upright positions on Effect of ionizing radiation on the binding of muscimol [IAF PAPER 89-5991 p39 A90-13631 central hemodynamics in patients with chest pain by synaptic membranes of the rat brain BAKER, SUSAN P. syndrome p 43 A90-15490 p 34 ABO-15640 Fatigue. pilot deviations and time of day BUCK, F. 0. ALEKSANDROV, A. [NASA-CR-185369] p62 N90-13035 Agerelated changes in human posture control: Motor Psycho-physiological studies during the fliht of the BALTZLEY, DENNIS R. coordination tests second Bulgarian wsnmnaut The time course of postflight simulator sickness [ NASACR-1858551 p6l N90-12178 [IAF PAPER 89-5861 p38 A90-13621 symptoms p40 A90-13735 BUCK, STEVEN D. ALEKSANDROVA, ZH. 0. Microcomputer-based tests for repeated-measures: A step in embryonic axis specbation in Xenopug laevis Accumulation of the biological effects of microwaves Metric properties and predictive valiis is simulated by cytoplasmic displacements elied by as displayed in the behavior, the physical efficiency.the [ NASACR-1855171 p52 N90-12174 gravity and centrifugal force p28 Am15073 body-mass increase, and the condition of cerebral A menu of self-administered microcomputer-based BUS, W. neurotoxicology tests neurons p33 A90-15637 lnfluemof gravitoinertial force on vestibular nystagmus [NASACR-185518] p52 N90-12175 ALEXANDRE, C. in man observed in a cenbifuge p 42 A90-15078 Nonnalisatbn of bone respMlses ocwn BAk7ABOl. V. A. teHular Pre and postftiiht postural control of the D1 Spacelab between 7 and 14 days of simulated weightlessness in Plant cell plasm membrane structure and propertks mission astronauts examined with a tilting room rats p31 Am15486 under ClinOataiiing p26 A90-15061 [ IZF-1988-251 p63 N90-13039 ALEXANDRE, M. BARANOV, V. Y. BLOCK, 1. Polarity of root statocytes in space and in simulated Cardiorespiratory responses to simulated microgravity weightlessness in man p44 A90-15505 Potential sites for the perceptionof gravity in the acellular slime mold PhySaNm polycephalum p 26 A90-15062 [IAF PAPER 89-6061 p23 ABO-13636 BARKAIA, V. S. Prevention of radiation sickness, induced by low-level BLOMOVIST, Q. ALLEN, JEFFREY K. ionizing radiation. by repeated injections with increasing Fluid distribution pattern induced by intravenous fliiid Prediction of thermal mess casualties doses of chemical radioprotecton p 33 A90-15633 loading during HDT [ADA2123561 p50 N90-13022 BARTILSON, BENJAMIN [IAF PAPER 89-5991 p39 A90-13631 ALLEN, L D. A diagnostic and environmental monitoring system BLOOMFIELD. S. Radio frequency (13.56 MM) energy enhances (DEMS) concept to support manned Mars in -fliht and Modifications of bone atrophy seen with hindlimb rewarming from mild hypothermia surface operations suspensbn by exercise and dobutamine [ADA2127031 p50 N90-13024 [AAS PAPER 87-2341 p60 A90-16533 p31 A90-15487 B-1 BOBKO, KAROL J. PERSONAL AUTHOR INDEX

-KO, KAROL J. BUONI, CORINNE M. The effect of caffeine on endurance time to exhaustion space Station Freedom crew training A diagnostic and environmental monitoring system at high altitude [IAF PAPER 890981 p51 A90-13308 (DEMS) concept to support manned Mars in -flight and [AD42120691 p47 N90-12163 BODZHIKOV, N. V. surface operations Immunocompetent cells producing humoral mediators [AAS PAPER 87-2341 p60 A90-16533 of bone tissue mineral metabolism during space flight BURXH, J. D simulation p43 A90-15496 lnterserosal pressures and circulatory homeostasis during changes in the gravitational inertial force BOER, L C. DALTON, B. P. Spatial tests for aviators environment p42 A90-15480 The rodent research animal holding facility as a barrier [IZF-198&151 p63 N90-13041 BURTON, RUSSELL R. to environmental contamination Periodic acceleration stimulation in a weightlessness [ NASA-TM-1022371 p 35 N90-12151 BOOMOLOV, V. V. environment (PASWE) - A new science? DANEVICH, L A. Medical results of the flight of the second prime crew p30 A90-15479 on orbital station Mir Calcium gradient in plant cells with polarized growth in the BUTLER, BARCLAY P. [IAF PAPER 89-5941 p 38 A90-13626 simulated microgravity p 26 ASO-15056 Regional aortic pressure apparent phase velocity in the DARDEN. E. E., JR. BOGSNES, A. baboon during 70 degree tilt p44 A90-15507 Reduced systolic blood pressure elevations during Galactic cosmic radiation exposure and associated maximum exercise at simulated altitudes health risks for air carrier crewmembers p 40 A90-13738 p41 A90-13745 C DAVIS, MICHAEL BOND, JAMES D. Fear-potentiatedstartle as a model system for analyzing Calcium displacement caused by electromagnetic CALLEJA, M. Insects as test systems for assessing the potential role learning and memory fields [AD-A212131] p53 N90-13029 [ADA2128901 p 50 N90-13023 of microgravity in biological development and evolution DEAMER, DAVID BONDE-PETERSEN, FLEMMING p27 A90-15071 CANADI, S. CATHERINE How did the first cells appear? p 63 A90-16035 Telescience tesmed for physiological experiments DEMATTEI, R. C. [IAF PAPER 89-0341 p 37 A90-13267 NASA spinoffs to bioengineering and medicine [IAF PAPER 89-6831 p40 A90-13673 Growth rate study of canavalin single crystals Hormonaland cardiovascular changes during lower body p34 A90-16420 CANALE-PAROU, E. negative and positive pressures DEMIN, NIKOLAI N. [IAF PAPER 89-6001 p39 A90-13632 Carbon cycling by cellulosefermenting nitrogen-fixing bacteria p30 A90-15442 Neurochemistry of hibernation in mammals Central venous pressure in humans during short periods p34 A90-16057 CARATERO, A. of weightlessness p44 A90-15504 Behaviour of single-cell organisms exposed to DEMKIV. 0. T. BONSI, CONRAD K. hypergravity Calcium gradient in plant cells with polarized growth in Utilization of sweet potatoes in controlled ecological lie [IAF PAPER 89-6071 p23 A90-13635 simulated microgravity p 26 ASO-15056 support systems (CELSS) p58 A90-15429 CARATERO, C. DENISOVA, L A. BOSS, WENDY F. Behaviour of sinale-cell orcanisms exWSed to The effect of microgravity on the reproductive function Membrane fusion: The role of polyphosphatidylinositol hypergravity of male rats p31 AM-15488 [ADA2112891 p36 N90-12156 [IAF PAPER 896071 p23 A90-13635 DEPEYRE, D. BOUVIER, JOHN CARRATALA. M. Polarity of root statocytes in space and in simulated Design guidelines for accommodation of robotic and Insects as test systems for assessing the potential role microgravity manipulative devices on Space Station Freedom of microgravity in biological development and evolution [IAF PAPER 89-6081 p 23 A90-13636 [ IAF PAPER 89-0841 p55 A90-13300 p 27 A90-15071 DEROSHIA, C. W. CARSIOTIS. MICHAEL Sinificance of light and social cues in the maintenance BRMK, L of temporal organization in man p 45 Ago-15512 Biomedical payload of the French-Soviet long duration Genetic engineering of enhanced microbial nitrification [PB89-208334] p 36 N90-12155 DINTENFASS, L flight - First conclusions Experiment on 'Discovery' STS 514 Aggregation of [IAF PAPER 89-5631 p37 A90-13606 CHANG, SXPHEN KW. - Human body regional convective heat transfer red cells and thrombocytes in heart disease, BRAUNSTEIN, MYRON L hyperlipidaemia and other conditions p 42 A90-1 5060 Discriminating rigid from nonrigid motion determination using sublimating naphthalene disks [AD42121 701 p47 N90-12165 DOERR, D. F. [AD-AZl 17941 p6.? N90-12180 Carotid baroreflex response following 30 days exposure BREGENZER, N. CHARLES, JOHN Effects of body posture on the interpretation of to simulated microgravity p 44 A90-15502 Unilateral centrifugation of the otoliths as a new method OONALDSON, P. LYNN to determine bilateral asymmetries of otoliith apparatus biomedical data obtained from manned missions the [IAF PAPER 89-5961 p39 Am-13628 USSR Space Life Sciences Digest, Issue 24 in man [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 [IAF PAPER 89.5661 p37 A90-13609 CHEN, CHAUCHYUN The role of computerized modeling and simulation in USSR Space Life Sciences Digest, Issue 22 BRIEGLEB, W. the development of lie support system technologies [NASA-CR-3922(26)-lSSUE-22] p 35 N90-12153 Potential sites for the perception of gravity in the acellular p 59 A90-15439 USSR Space Life Sciences Digest. Issue 23 slime mold Physarum polycephalum p 26 A90-15062 CHIKVASHVILI, D. V. [NASA-CR-3922(27)-ISSuE-23] p 36 N90-12154 Light microscopic analysis of the gravireceptw in Radioprotective effects of ATP and ADP on DOUBT, T. J. Xenopus larvae developed in hypogravity membraneboundenzymes p33 A90-15635 Effects of serial wetdry-wet cold exposure: Thermal p28 A90-15081 balance, physical activity, and cognitive performance BROOKS. W. S C. CONSTABLE, STEFAN H. [ADA21 27041 p51 N90-13025 Prediction of thermal stress casualties Gas bubble coalescence in reduced gravity conditions DRISSECOLE, D. p50 N90-13022 p 30 A90-15446 [ADA21 2356 I lmpottance of the lgcontrols in interpreting the resuns BROWN, J. W. CONVERTINO, V. A. of an emriment on Dlant.- cravitrooism .. 1Biorack. D1 Human factors and productivity on Space Station Carotid baroreflex response following 30 days exposure mission) Freedom to simulated microgravity p 44 A90-15502 [IAF PAPER 89-6091 p24 A90-13637 [IAF PAPER 89-0871 p 55 A90-13301 CONVERTINO, VICTOR A. DUDLEY. GARY A. BROWN, JAMES Changes of muscle function and size with bedrest Changes of muscle function and size with bedrest The effect of incentives on the reliability and validity of p 43 A90-15501 p43 AW-15501 cognitive speed tests CONWAY, TERRY L DUECKMAN, J. H. [ADA21 13481 p62 N90-12181 Demonstration of replicable dimensions of health Requirements and concepts for the Space Station BROWN, L V. behaviors Remote Manipulator System Effect of increased acceleration on lung expansion in [AD-A211920] p46 N90-12161 llAF PAPER 89-0691 D 55 A90-13289 dogs - Prone vs. supine body positions CORNEC, FRANCOIS DUKE, J. p33 A90-15500 State of the art of humanimachine dialog tool Continuing studies of 'CELLS flight hardware BROWNING, RONALD K. p~totypes D 32 A90-15497 The Flight Telerobotic secvicer - NASA's first operational [TELECOM-PARIS89-H001I p 62 N90-13038 DUNLAP, WILLIAM P. space mbot COTE, F. Microcomputer-based tests for repeated-measures: [IAF PAPER 890501 p54 A90-13277 Effect of C02 and 02on development and fructification Metric properties and predictive validities BRUCKNER-LEA, CINDY of wheat in closed systems p 57 A90-15428 [NASA-CR-185517] p52 N90-12174 Investigation of resonant acdc magnetic field effects COURTNEY. T. H. DUNLOP, E. H. [ADA21 16121 p37 N90-12159 Shape instabilities of platelike structures. 1: Phase separated membrane bioreactor - Resuns from BUCHANAN, PAUL Experimental observations in heavily cold worked in situ model system studies p60 A90-15447 Changes of muscle funcbon and size with bedrest composites DURNEY. CARL H. p43 A90-15501 [ADA2122511 p50 N90-13021 Investigation of resonant ac& magnetic field effects BUGBEE, 8. G. [ADA2116121 p 37 N90-12159 Current potential productivity of wheat for a CRAMPTON. GEORGE H. DVORAK, J. and 8-OH-DPAT supQresses vomiting in the cat elicited by controlled environment life sum system motion. cisplatin or xylazine p 34 A90-18286 Pilot performance is increased after alternating hypc- p 57 A90-15427 and hypergravity states p 45 A90-15511 BUGROV, S A. CUSHMAN, WILLJAY 8. Medical results of the flight of the second prime crew A Scheiner-principle pocket optometer for on the orbital station Mir self-evaluation and biofeedback accommodation training E [IAF PAPER 89-5941 p38 A90-13626 [ADA2131711 p51 N90-13027 BULA, RAYMOND J. CYMERMAN, ALLEN ECKBERG, D. L Utilikation of white potatoes in CELSS Ropranolol and the compensatory circulatory responses Carotid baroreflex response following 30 days exposure p58 A90-15431 to orthostasis at high altitude p40 A90-13736 to simulated microgravity p44 A90-15502

B-2 PERSONAL AUTHOR INDEX GRIGOR’EV, A. 1.

EGOROV, A. D. FLERI, EWAR L. JR. GENIN, A. M. Mediil results of the fliht of the second prime crew Proposal for a zerogravity toilet facility for the space Cardiorespiratocy responses to simulated on the &tal station Mir Station weightlessness in man p44 A90-155068 [IAF PAPER 89-5941 p 38 A90-13626 [ NASA-CR-1831511 p62 N90-13036 GERBAUD, A. EICHOLD, ALICE FOLDAGER, NIELS Effect of 02and 02 on development and fructification A zer0-g CELSSlrecreation facility for an earthMars Central venous pressure in humans during short periods of wheat in closed systems p 57 A90-15428 crew shuttle of weightless- p 44 A90-15504 GERECHT, KLAUS [AAS PAPER 87-2351 p61 A90-16534 FORTE, VINCENT A., JR. Biochemical and physiological changes in glider pilots EIDESYO, T. The effect of caffeine on endurance time to exhaustion during multihour flights Rhythmic biological systems under micro-g conditions at high altitude [DLR-FB-89-29] p49 N90-13018 p29 A9015084 [ADA2120691 p47 N90-12163 GERZER, R. EIKEN, 0. FREI, W. Fluid distribution pattern induced by intravenous fluid Responses to changed perfusion pressure in working Simulation by personal workstation for Man-Machine loading during HDT muscles - Factors to be CMlsidered in exercise testing in Interface design [IAF PAPER 89-5991 p39 A90-1363‘1 space flights? p42 A90-15481 [IAF PAPER 894891 p55 A90-13302 GHARIB, C. Plasma ANF concentrations during headdown bed rest ELISTRATOVA, ZH. V. FRIEDBERG. W. of various duration (from several hours to one month) Prevention of rsdiation siclmess, induced by low-level Galactic cosmic radiation emsure and associated - Role of LBNP wuntermeasure p 44 A90-1550:) ionuing radiation, by repeated injections with increasing health risks for air dercrewmembers GHIRARDELLI, ROBERT 0. doses of chemical radioprotectom p 33 A90-15633 p41 A90-13745 ELLER, NANCY Boron analogues of amino acids and derivatives FRIEDRICH, U. [ADA2113111 p36 N90-12157 Synergistic effects of nitrogen dioxide and catbondioxide Gravitational biology within the German microgravity following acute inhalation exposures in rats GIBSON. EDWARD 0. program - Cument status and further pursuits Space Station Freedom crew training [PB89-214779] p35 N90-12150 [IAF PAPER 89-6121 p24 A90-13640 [IAF PAPER 89-0981 p51 A90-13308 ELMANN-LARSEN. BENNY FRIY, JOHN GILKEY, ROBERT H. Central venous pressure in humans during shod periods Head owling is desirable but not essential for preventhg Binaural masking: An analysis of models of weightlessness p 44 A90-15504 heat strain in pilots p57 AM-13737 [ADA2115781 p48 N90-12168 EYIRBEKOV, EYIRBEK 2 FRITSCH, J. Y. GIRTEN, B. Neurochemislty of hibemation in mammals Carotid baroreflex response following 30 days exposure Modifications of bone atrophy seen with hindlimb p34 A90-16057 to simulated microgravity p44 A90-15502 suspension by exercise and dobutamine EVANICH, PEGGY FUJII, M. pat A~O-15487 The role of computerized modeling and simulation in Plant cultural system incorporated into CELSS Skeletal muscle antioxidant enzyme levels in rats after the development of life support system technologies [IAF PAPER 80-5801 p57 A90-13619 simulated weightlessness, exercise and dobutamine p59 A90-15439 FUJII, SHIGEO p 32 A90-15498 EVELAND, E. Closed and continuous algae cultivation system for food GITEL’SON. 1.1. Modifications of bone atrophy seen with hindlimb production and gas exchange in CELSS Long-term experiments on man’s stay in biological suspension by exercise and dobutamine p60 A90-15445 Me-support system p58 A90-15433 p3t A90-15487 FUJII, T. GLADKIKH, F. D. Skeletal muscle antioxidant enzyme levels in rats after A foodlnutrient supply plan for lunar base CELSS The effect of occupational work load on the functional simulated weightlessness. exercise and dobutamine [IAF PAPER 89-5791 p56 A90-13618 state of naval-aviation flight personnel p 32 A90-15496 FULCO, CHARLES S. p 41 A90-1442!5 GOGOLI. A. EVENS, MARTHA Propranololand the compensatorycirculatocy responses Life sciencesand research XXlll(5) Gravitational Computer generation of a tutorial dialogue to orthostasis at huh altitude p 40 A90-13736 space - biology; Proceedings of the Topical Meeting and [AD-A21 19761 p46 N90-12162 The effect of caffeine on endurance time to exhaustion EWALD, J. Workshqa Wll and Wlll of the 27th COSPAR Plenary at high altitude Meeting. Espoo. Finland, July 18-29. 1988 Studies on Habitation Module and interconnecting [AD-A212069] p47 N90-12163 elements for a future European space station p 25 A90-15051 FULLER, CHARLES A. GOLDSBERRY, 8. S. [IAF PAPER 89-0921 p 55 A90-13305 The biological clock of Neurospora in a microgravity Using computer graphics to design Space Station environment p29 A90-15062 Freedom viewing Gravitational biology and the mammalian circadian IIAF PAPER 89-0931 p56 A90-13306 F timing system p29 A90-15085 QOLLNICK, PHILIP D. Temperature regulation in rats exposed to a 2 G field Changes of muscle function and size with bedrest FAULKNER, D. N. p32 A90-15499 p 43 A90-15501 Galactic cosmic radiation exposure and associated FURUUNE, HlROVUKl GOLOV, E. IU. health risks for air canier crewmembers Dependence of the ampliiude of kinesthetic evoked p41 A90-13745 Design for a bioreactor with sunlight supply and operatins systems for use in the space environment potentials on the velocity and acceleration of the motion FEDAN, V. A. p 59 AM-15444 of a monkey’s hand p 24 A90-14446 Dependence of the amplii of kinesthetic evoked GOYA, K. potentials on the velocity and acceleration of the motion Design and evaluation of man-in-theloopcontrol system of a monkey’s hand p24 A90-14446 of Japanese Experimental Module Remote Manipulator FEIGELSON, R. S G System Growth rate study of canavalin single crystals GALE, J. [IAF PAPER 89-0901 p 55 A90-13303 p34 A90-16420 Carbon balance and productnrity of Lema gibba, a GONCHARENKO. E. N. FELL, R. candidate plant for CELSS p 58 A90-15430 Effect of ultrahighdose ionizing radiation on the content Biochemical and histochemical observations of vastus GALLIANO, PAUL A. of cathecholamine mediators in various regions of the rat medialis from rats flown in Cosmos 1887 (experiment Proposal for a zerc-graviiy toilet facility for the space brain p34 A90-15641 K608) p31 A90-15484 station GONZALEZ-JURADO. J. FERRARO, JAMES S. [NASAGR-1831511 p62 N90-13036 Insects as test systems for assessing the potential role The biological clock of Neurospora in a microgravity GANESAN, 5. of microgravity in biological development and evolution emrirOnnlWlt p29 A90-15082 Effect of increased ameleration on lung expansion in p27 A90-15071 FERRUA, 8. dogs - Prone vs. supine body positiona QONZALEZ, 0. Study of activation of human peripheral blood p 33 A90-15500 Occupational injuries sulfered by flight attendants while mononuclear cells after a space fliht GANlT, DAVID S. on board p41 A90-13746 [IAF PAPER 89-611 I p 24 A90-13639 Effects of transition from supine to upriaht positions on GONZALEZ, RICHARD R. FICKOVA, W. central hemodynamics in patients chest pain Human body regional convective heat transfer Effect of space flihts and hypokinesia on plasma insulin syndrome p43 A90-15490 determination using sublimating naphthalene disks levels and insulin receptors in rat river GARSHNEK, VICTORIA [ADA21 21701 p47 N90-12165 USSR Space Life Sciences Digest lasue 24 [IAF PAPER 89-5641 p23 A90-13607 aosSAIN. D. Y. [NASA-CR-3922(28)-lSSUE-24] p 35 NW-12152 FIEBAG, JOHANNES Requirements and concepts for the Space Station USSR Space Life 3.5 billion years ago: Life on Mars? Hints, indications, Sciences lasue 22 Remote Manipulator System [NASACR-3922(28)-lSSUE-22] p 35 N90-12153 speculations p64 A90-16380 [IAF PAPER 890691 p55 A90-13289 USSR Space Life Sciences Diilasue 23 FILBERT, HAROLD E. [NASA-CR-3922(27)-lSSUE-23] p 36 N90-12154 GOWER, DANIEL W. Astronaut interdisciplinary and mediilldental training GAUQUELIN, G. The time course of postflight simulator sickness for manned Mars missions Plasma ANF concentrations duing headdorm bed rest symptoms p40 A90-13735 [AAS PAPER 87-2381 p46 A90-16537 of various duration (fmm’several hars to one month) - GRIQOR’EV, A. D. FISHER, JOSEPH R. Role of LBNP countemasure p 44 A90-15503 Biomedical payload of the French-Soviet long duration Recavery to +tGz and +Xz following +Gz-induced GAZENKO, 0.0. fliht - First conclusions loas of consciousness - OperaW considetations Mediil results of the fliiht of the second prime crew [IAF PAPER 89-5631 p37 A90-131306 p41 A90-13741 on the wtital station Mir GRIGOR’EV, A. 1. FISK, ARTHUR D. [IAF PAPER 89-5941 p38 A90-13626 Changes in kidney response to ADH under hypogravity

Effects of type of responding on menwy/visual search: GEELEN, 0. ~ Rat models and possible mechanisms Responding just yes or just no can lead to inflexible Plasma ANF concentrations during head- bed rest p30 A90-15482 w-n- of various duration (from several hours to one month) - Calcium homeostasis in prolonged hypokinesia [ADA2127641 p 53 N90-13033 Role of LBNP mntermeasure p 44 A90-15503 p 43 A90-15.492 8-3 GRIGORIEV, A. 1. PERSONAL AUTHORINDEX

GRIGORIEV. A. 1. HIRZINGER, QERD IVANOVA, L N. Medii1 results of the fliht of the second prime crew West Germany's first space robot p 57 A90-14999 Changes m kidmy response to ADH under hypogravity on me station Mir HOFFMAN, DONALD D. - Rat models and possible mechanisms [IAF PAPER 89-5941 p 38 A90-13626 Discriminating rigii from nonrigii motion p30 A90-15482 GUELL, A. [ADA21 17941 p62 N90-12180 IWATA, TSUTOMU Biomedical payload of the French-Soviet long duration HOFFMANN, HA. Development of the 2nd generation space robot in fliht - First conclusiOns Gravitational biology within the German microgravity NASDA [IAF PAPER 89-5631 p37 A90-13806 program - Current status and further pursuits [IAF PAPER 880511 p 54 A90-13278 GUELL, ANTONIO [IAF PAPER 89-6121 p24 A90-13640 IZUTANI, NAOAKI orthostatic intolerance post space fliht - A multifactwial HOGAN, PERRY M. Oxygen separation system of residential space at the tiidel? Cellular and molecular mechanisms of hih pressure lunar base [IAF PAPER 89-5951 p39 A9013627 inotropy in cardiic muscle [IAF PAPER 89-5741 p 56 Am-13613 [ADA2116951 p48 N90-12170 GUUENNEC, C. V. Hemodynamics of leg veins during a 30 days bed rest HOGAN. R. P. - Effect of lower body negative pressure (LBNP) The rodent research animal holding faalii as a banier J p45 A90-15508 to environmental contamination [NASA-TM-102237] p35 N90-12151 GULKIS, S JACOBS, 1. The NASA SET1 sky survey: Recent developments HOLLEV, D. C. The effect of concurrent strength and endurancetraining p64 N90-12804 Significance of light and social cues in the maintenance on eleclromechanical delay, maximum voluntary temporal organization in man p 45 A90-15512 of contradon, and rate of force development HOLSTEGE, GERT [AD42133161 p51 N90-13028 H Anatomical study of the final common pathway for vocalization in the cat p34 A90-16284 JACQUU, R. Sources and processing of CELSS wastes HOMER, L D. HAGAMAN. JANE A. p 59 A90-15435 Space Station accommodation of life sciences in support Radio frequency (13.56 MHz) energy enhances JAHNS, 0. C. I of a manned Man mission rewarming from mild hypothermia [AAS PAPER 87-2331 p35 Am-16532 [ADA2127031 p50 N90-13024 The rodent research animal holding facility as a banier HAGEN, JOEL HONEYCUTT, CLEGG to environmental contamination JANATA,[NASA-TM-102237] JlRl p35 N90-12151 Considerations for the living areas within space Plasma stress hormones in resting rats ~ Eghty four settlements day study p32 A90-15489 [AAS PAPER 87-2421 p61 A90-16541 HOKE, LYDIA RURAN Investigation of resonant acdc magnetic field effects HANSSON, P. A. USSR Space Life Sciences Digest. Issue 24 [AD421 16121 p37 N90-12159 Work on human adaptation to long-term space flight in [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 JANIK, D. me UK USSR Space Lite Sciences bgest, Issue 22 Effect of iodine disinfection products on higher plants [AAS PAPER 87-2371 p 46 A90-16536 [NASA-CR-3922(26)-lSSUE-22] p 35 N90-12153 p29 A90-15438 HARDIECK. K. USSR Space Life Sciences Digest, Issue 23 JANNASCH. H. W. Hemodynamics during head down tilting and lower body [NASA-CR-3922(27)-ISSUE-23] p 36 N90-12154 Evidence for anoxygenic photosynthesis from the negative pressure end pharmacological interventions for HORNECK, G. distribution of bacteriochlorophylls in the Black Sea countermeasures Life sciences and space research XXlIl(5) - Gravitational p 24 A90-14631 [ IAF PAPER 89-5971 p 39 A90-13629 biology; Proceedings of the Topical Meeting and JAROSIUS, A. V. HARGENS, ALAN R. Workshops XVll and XVlll of the 27th COSPAR Plenary Evaluation of experiments involving the study of plant Decreased swelling pressure of rat nucleus pulposus Meeting, Espoo, Finland, July 18-29, 1988 orientation and growth under different gravitational associated with simulated weightlessness p25 A90-15051 conditions p25 A90-15053 HUBBARD, ROGER W. p31 Am15485 JOHANSEN, STAEHR TORBEN Heatstroke pathophysiology: The energy depletion HARMON, V. Central venous pressure in humans during short periods model Radio frequency (13.56 MHz) energy enhances 01 weightlessness p 44 A90-15504 rewarming from mild hypothermia [AD-AZl 21561 p47 N90-12164 Exertional heatstroke: An international perspective. An JOHNSON, WILLIAM E. [ADA2127031 p50 N90-13024 Proposal for e zero-gravity toilet facility for the space HARRIS, JOSEPH introduction: The role of exercise in the etiology of exertional heatstroke station I Prediction of thermal stress casualties [NASA-CR-183151] p 62 N90-13036 [AD-A212356] p50 N90-13022 [AD-A2122421 p50 N90-13020 HARRISON, ALBERT A. HUGHES-FULFORD, M. JOHNSON, A. Individual differences, mission parameters, end Thin film bioreactors in space p 27 A90-15068 Rhythmic biological systems under microg conditions spaceflight environment habitabilii HUNTON, CAROLYN LEACH p 29 A90-15084 [AAS PAPER 87-2401 p61 A90-16539 Space physiology and medicine (2nd edition) JORDAN, CAROL A. HARRISON. MARK E. p 46 A90-16625 Calcium displacement caused by electromagnetic Proposal for a zerogravity toilet facility for the space fields station [ADA21 26901 p50 N90-13023 [NASACR-183151] p 62 N90-13036 I JORGENSEN, 8.8. HARTZELL, GORDON E. Evidence for anoxygenic photosynthesis from the Advances in combustion toxicology. Volumes 1 8 2 IGLESIAS, R. distribution of bacteriochlorophylls in the Black Sea p24 A90-13903 Occupational injuries suffered by flight attendants while p24 A90-14631 on board p4t A90-13746 I HASENCLEVER, SILKE RUTH Effects of e time zone shin of nine hours on the circadian IIKURA, S. rhymms in cockpct aircrew members on longhaul flights Active vibration control for flexible space environment K [DLR-FB-89-31] p49 N90-13019 use manipulators p60 A90-16522 HEER, M. IL'IN, E. A. KAMINSKAIA, E. V. Fluid distribution pattern induced by intravenws fluid Microgravity end musculoskeletal system of mammals Effects of prolonged exposure of lettuce seeds to HZE I loading during HDT p25 A90-15052 particles on orbital stations p26 A90-15058 [IAF PAPER 89-5991 p39 A90-13631 Studies of space adaptation syndrome in experiments KAMINSKI, MARK HERVIQ, LINDA K. on primates performed on board of Soviet biosatellite Investigation of resonant acdc magnetic field effects Demonstration of replicable dimensions of health 'cosmos-1 887' p 32 ~90-15494 [AD42116121 p37 N90-12159 behaviors ISAMBERT, A. KAMPE, J. C. MALLIHN [ADA2119201 p46 N90-12161 Polarity of root statocytes in space and in simulated Shape instabilities of plate-like . structures. 1: I HESSUNK, R. L micrograwly Experimental observations in heavily cold worked in situ Radio frequency (13.56 MHz) energy enhances [IAF PAPER 89-6081 p 23 A90-13636 COmpOSites rewarming from mild hypothermia ISHAY, JACOB S. [ADA2122511 p 50 N90-13021 [ADA2127031 p50 N90-13024 Geotropic sensitivity of hornets p 27 A90-15072 KARLINS, MARVIN Effects of serial wetdry-wet cold exposure: Thermal ISHIHAMA, LINDA M. The spousal factor in pilot stress p 52 A80-13747 balance. physical activity. and cogn~eperformance Temperature regulation in rats exposed to a 2 G field KASS, J. [ADA2127041 p51 N90-13025 p32 A90-15499 Influence of proprioceptive information on space HIQHBARQER, LANE orientation on the ground and in mtal weightlessness ISLAMOV, IU. N. Synergisticeffectsofnitrogendioxideandcarbondioxide p42 A90-15079 , following acute inhalation e-res in rats Radioprotective properties 01 a Co(lll) biocomplex KATKOV, V. E. [ PB89-2147791 p 35 N90-12150 p33 A90-15634 Cardiorespiratory responses to simulated HILL, WALTER A. ISLAMOV, U. N. weightlessness in man p44 A90-15505 Utiliition of sweet potatoes in controlled ecological life Radioprotective properties of a cO(lIl) biooomplex KATUNTSEV, V. P. support systems (CELSS) p 58 A90-15429 p 33 Ago-15634 Cardiorespiratory responses to simulated HILLEBRECHT, A. ISOZAKI. KVOKO weightlessness in man p44 A90-15505 Fluid distribution pattern induced by intravenous fluid Design for a boreactor with sunlight supply and KAURIAN, L loading during HDT operations systems for use in the space environment Modifications of bone atrophy seen with hindlimb [IAF PAPER 89-5991 p39 A90-13631 p 59 Am-15444 suspension by exercise and dobutamine HILLVARD, STEVEN A. IURINSKAIA, M. M. p31 A90-15487 Electrophysiological studies of visual attention and Effect of ionizing radiation on the binding of muscimol KAZEIKIN, V. S. resource allocation by synaptic membranes of the rat brain Miogravity-induced changes in human bone strength [ADA2122871 p53 N90-13030 p 34 A90-15640 p 43 A90-15493

8-4 PERSONAL AUTHOR INDEX LU, JOHN Y.

KENNEDY, ROBERT S. KOTUR, MARK S LEACH-HUNTOON. CAROLYN The time course of postfliiht simulator sickness A diagnostic and environmental monitoring system Effects of body posture on the interpretation of symptoms p40 AM-13735 (DEMS) concept to support manned Mars in -flight and biomedical data obtained from manned missions Microcomputer-based tests for repeated-measures: surface operations [IAF PAPER 89-5961 p 39 A90-1362fI Metric properties and predictive valiiis [AAS PAPER 87-2341 p60 A90-16533 LEACH, C. S. [ NASA-CR-1855171 p52 N90-12174 KOVROV, 6.0. Human factors and productivity on Space Statiori A menu of self-administered microcomputer-based Long-term experiments on man's stay in biological Freedom neurotoxhlogy tests liesupport system p 58 A90-15433 [IAF PAPER 894871 p55 A90-1330'1 [NASA-CR-185518] p52 N90-12175 KOZLOVSKAIA, 1.6. LEACH, CAROLYN S KENSTAVICIENE. P. F. Studies of space adaptation syndrome in experiments Biochemical correlates of neurosensory changes in I Formation and growth of callus tissue of AraMopsis on primates performed on board of Soviet biosatellite weightlessness under changed gravity p 25 A90-15055 'mnWS-1887' p32 A90-15494 [IAF PAPER 89-5981 p 39 A90-13830 KHAKIMOV, P. A. KOZLOWSKI, R. LEBOUARD, D. Radopcotective propertie% of a Co(lll) biowmplex The next 40 years in space - Aspects of human factors Effect on the cardiac function of repeated LBNP during p 33 A90-15634 in space research a one month head down tilt KHANNA, SUNIL [IAF PAPER 89491I p37 A90-13304 [IAF PAPER 89-5931 p38 A90-13626 Genetic engineering of enhanced microbial nitrification LEHTONEN, E. KRAHENBUHL, GARY S [PB89-208334] p36 N90-12155 Early development in the mouse Would it be affected Prediction of thermal stress casualtias - KIKUCHI, KATSUTOSHI by microgravity? p 28 Am-15077 [ADA2123561 p 50 N90-13022 Study on the nitrogen fixation system required for plant LENG, Y. culture in a lunar base KRAVIK, STEIN E. Shape instabilities of plate-like structures. 1: [IAF PAPER 89-5751 p56 A90-13614 Cardiovascular, renal, electrolyte. and hormonal Experimental observations in heavily cold worked in situ KITAYA, Y. changes in man during gravitational stress. composites Plant cultural system incorporated into CELSS weightlessness, and simulated weightlessness: Lower [ADA2122511 p50 N90-13021 [IAF PAPER 89-5801 p 57 A90-13619 body positive pressure applied by the antigravity suit LEONARD, JOEL 1. KIYOTA, Y. [ NASA-TM-1022321 p49 N90-13013 Effects of body posture on the interpretation of Plant cultural system incwporated into CELSS KREUZBERG, K. biomedical data obtained from manned missions [IAF PAPER 89.5801 p57 A90-13619 Gravitational biology within the German microgravity [IAF PAPER 89-5M1 p39 A90-13628 KLEIER, DONALD J. program - Current status and further pursuits LESCHINE, S. 8. Astronaut interdisciplinary and madiilldental training [IAF PAPER 89-6121 p 24 A90-13640 Carbon cycling by cellulose-fermenting nitrogen-fixing for manned Mars missions KRUSE, 8. bacteria p 30 A90-1544.2 [AAS PAPER 87-2381 p46 Am-16537 Light microscopic analysis of the gravireceptor in LESNIAK. A. 1. KLEIN, Y. J. Xenopus larvae developed in hypogravity Immunocompetent cells producing humoral mediators The NASA SET1 sky suwey: Recent developments p28 A90-15081 of bone tissue mineral metabolism during space fliiht p64 N90-12804 KUNTL, LOISANN simulation p43 AW-154~ KLIMCHUK. D. A. Microcomputer-based tests for repeated-measures: LEVIN, BARBARA C. Prospeas of studies in space phyiobiology Metric properties and predictive validities Synergisticeffects of nitrogen dioxide and carbon dioxide [IAF PAPER 89.5781 p 23 A90-13617 [NASA-CR-185517] p52 N90-12174 following acute inhalation exposures in rats Plant call plasma membrane structure and properties A menu of self-administered microcomputer-based [ PB89-2147791 p 35 N90-121!50 under clinostaiting p26 A90-15061 neurotoxicology tests LEWIS, J. L, JR. KNAPP, C. F. [NASACR-185518] p 52 N90-12175 Using computer graphics to design Space Station Effect of increased acceleration on lung expansion in KURAOKA, K. Freedom viewing dogs Prone vs. supine body po&ns - Cksgn and evaluationof man-in-the-loopcontrol system IIAF PAPER 89-0931 p 56 A90-13306 p33 A90-15500 of Japanese Experimental Module Remote Manipulator LEWIS, S. 8. KNUDRON, J. System Radio frequency (13.56 MHz) energy enhances Reduced systolic blood pressure elevations during [IAF PAPER 89-0901 p 55 A90-13303 rewarming from mild hypothermia maximum exercise at simulated altitudes LAD42127031 p 50 N90-13024 KUZNRSOV, V. 1. p 40 A90-13738 LILIENTHAL, MICHAEL 0. Effect of ionizing radiation on the binding of muscimol KOH, FREDDIE The time course of postflight simulator sickness by synaptic membranes of the rat brain The spousal factor in pilot stress p 52 A90-13747 symptoms p 40 A90-13735 p 34 A90-15640 KOLOYYTKIN, 0. V. LIYOUSE, Y. Effect of ionizing radiation on the binding of muscimol KYLLONEN, PATRICK C. Study of activation of human peripheral blood by synaptic membranes of the rat brain Individual differences in associative learning and mononuclear cells after a space flight p34 A90-15640 forgeiting [IAF PAPER 89-611 ] p 24 A90-13639 KOLOSOVA, SVETLANA A. [ADA2127651 p54 N90-13034 LINKE-HOYYES, A. Binocular depth perception and its hyperacuity in Gravity and the membranesolution interface - common and specialty selected subjects Theoretical investigations p 26 A90-15059 [IAF PAPER 89-5881 p 38 A90-13622 L LIPPERT, B. 0. KOYATSU, T. Using computer graphics to design Space Station Active vibration control for flexible space environment LAI-FOOK, S. J. Freedom viewing use manipulators p60 A90-16522 Effect of increased acceleration on lung expansion in [IAF PAPER 890931 p56 A90-13306 KONSTANTINOVA. 1. dogs - Prone vs. supine body positions LISOVSKII, G. M. Study of activation of human peripheral Mood p33 A90-15500 Long-term experiments on man's stay in biological mononuclear cells after a space flght LAN, JlANaUAN lifeeupport system p 58 A90-15433 [ IAF PAPER 89611 ] p 24 A90-13638 Experimental research on the applicabilitiesof Chinese LIU, KEJIA KONSTANTINOVA, 1. V. medicine to space medicine Changes in circadian rhythm of multiple hwmones and Immunocompetent cells producing humoral madietors [IAF PAPER 89-601 ] p39 A90-13633 their relationship with indiiual susceptibility in simulated of bone tissue mineral metabolism during space flight LARSON, GERALD E. weightlessness simulation p43 AW-15496 The effect of incentives on the reliability and valiii of [IAF PAPER 89-5651 p37 A90-13W8 KOO, C. cognitive speed tests LOELLGEN, H. Sources and processing of CELSS wastes [ADA2113461 P62 N90-12181 Hemodynamics during head down tilting and lower body p 59 A90-15435 LASSEUR, CH. negative pressure and pharmacological interventions for I Subuitical and supercritical water oxidation of CELSS The C23A - First step to a monitoring system of CELSS countermeasures model wastes p 59 A90-15436 in flght p 59 A90-15437 [IAF PAPER 89-5971 p 39 A90-13629 KOPPENHAGEN, K. LATHAM, RlCKY D. LOEPPKY. J. A. Hemodynamics during head down tilting and lower body Gravitational influence on systemic arterial dynamics Work capacity, exercise responses and body negative pressure and pharmacological interventions for using a 3-element Windkessei model p 44 A90-15506 composition of professional pilots in relation to age countermeasures Regional aoftic pressure apparent phase velocity in the p 40 A90-13739 [IAF PAPER 89-5971 p 39 A90-13629 baboon during 70 degree tin p 44 A90-15507 LOn, HORNQ-HAI I KORDIUY. E. L LAURINAVICIUS, R. S. Three dimensional object recognition emplo)ing Prospects of studii in apace phyiobio~ogy Evaluation of experiments involving the study of plant combined visual and tactile sensing [IAF PAPER 89-5783 p23 A90-13617 orientation and growth under different gravitational [PB89-219489] p 52 N90-12176 cell mechanisms of adaptation to main factors of space condiim p25 ASO-15053 LORENZI, 0. flight Formation and growth of callus tissue of Arabidopsis Polarity of root statocytes in space and in simulated [IAF PAPER 898081 p 23 A9013634 under changed gravity p 25 A90-15055 microgravity p 23 A90-131536 Plant cell in the process of the adaptation to simulated LAURSEN, E. F. [IAF PAPER 89-6081 miuograviIy p25 A90-15054 Innovative approaches to the design of bwegenerative LORETAN, PHILIP A. Calcium gradient in plant cells with polarized growth in life support systems for advanced missions Utilization of sweet potatoes in controlled ecological life simulated microgravity p 26 A90-15056 [IAF PAPER 894261 p 54 A90-13261 support systems (CELSS) p 58 A90-15429 Ultrastructural and growth indices of Chlorella culture LAZERGES, Y. LOUISY, FRANCIS in multicomponent aquatic systems under space tight Selective hypergravity stimulation: Its effects on the Hemodynamics of leg veins during a 30 days bed rest

condiins p27 A9015063 ~ human balance and gait functions ~ A model to assess, Effect of lower body negative pressure (LBNP) KOROL'LKOV, V. 1. in normal gravity conditions, some aspects of the p45 A90-15508 Studies of apace adaptation syndrome in experiments perturbations induced on human body by microgravity LU, JOHN Y. on primates performed on board of Soviet biosatellite condiins Utilization of sweet potatoes in controlled ecological life 'cosmokl887' p32 A90-15494 [IAF PAPER ST49-0161 p40 A90-13729 support systems (CELSS) p 58 A90-15429

8-5 LU. JUN PERSONAL AUTHOR INDEX

LU, JUN MARENDAZ, CHRISTIAN Formation and growth of callus tiwe of Arabidopsis Changes in circadian rhythm of multiple hormones and Psychologicalmechanisms involved in the disorientation under changed gravity p 25 A90-15055 their relationship with indiiual susceptibility in simulated of pilots due to fliht conditions MEROU, A. J. weightlessness [ETN49-95014] p63 N90-13040 Skeletal muscle antioxidant enzyme levels in rats after [IAF PAPER 89-5651 p 37 A90-13608 MARONEV, SUSAN A. simulated weightlessness. exercise and dobutamine LUCK, S. J. Space Station Freedom crew training p32 A90-15498 Electrophysiological studies of visual attention and [IAF PAPER 890981 p51 A90-13308 MEYER, GREGORY J. resource allocation MARTIN, E. Proposal for a zerogravity toilet facility for the space [APA212287] p 53 N90-13030 Unilateral centrifugation of the otoliths as a new method station LUCOT. JAMES 0. to determine bilateral asymmetries of the otolith apparatus [NASA-CR-183151] p 62 N90-13036 8-OH-DPAT suppresses vomiting in the cat elicited by in man MICHAEL, JOEL motion, cisplatin or xylazine p34 A90-16286 [IAF PAPER 89-5661 p 37 A90-13609 Computer generation of a tutorial dialogue LUDWIG, K.-P. MARTIN, 0. M. [ADA21 19761 p46 N90-12162 Prospects of studies in space phytobiology Modular A8R system testbed for development and MIDDLETON, J. A. implementationof automationand robotics elements within [IAF PAPER 89-5781 p 23 A90-13617 MASSABUAU, M. Requirements and concepts for the Space Station future orbiil systems Remote Manipulator System [fAF PAPER 89-0361 p54 A90-13269 Effect on the cardiac function of repeated LBNP during a one month head down tilt [IAF PAPER 89-0691 p 55 A90-13289 LUFT. u. c. MIWRIKAWA, Y. Work capacity, exercise . responses and body [IAF PAPER 89-5931 p38 A90-13625 MASSIMINO. 0. A foodlnutrient supply plan for lunar base CELSS composition of professional pilots in relation to age [IAF PAPER 89-5791 p56 A90-13618 p 40 A90-13739 Effect of C02 and 02 on development and huctihcation of wheat in closed systems p57 A90-15428 MlGlNIAC, R. LUO, REN C. Simulation by personal workstation for Man-Machine Three dimensional object recognition employing The C23A. First step to a monitoring system of CELSS in flight p59 A90-15437 Interface design combined visual and tactile sensing [IAF PAPER 890891 p 55 A90-13302 [ PB89-2194891 p52 N90-12176 MASSIMINO, J. LYNCH, GARY Effect of C02 and 02 on development and fructification MIKHAILOV, AL'FA I. of wheat in closed systems p 57 A90-15428 Synaptic plasticity and memory formation How did the first cells appear? p 63 A90-16035 [AD421 13681 p36 N90-12158 MATSUMOTO, KANJI MILLER, A. T. Design for a bioreactor with sunlight supply and Biological effects of galactic radiation HZE particles in operations systems for use in the space environment experiments on the orbiil station Salyut 7 M p 59 A90-15444 p26 A90-15057 MATUI, NOBUO MILLER, LARRY S. MACDOUGALL, J. D. Telescience testbed for physiological experiments A diagnostic and environmental monitoring system The effect of concurrent strength and endurance training [ IAF PAPER 890341 p37 A90-13267 (DEMS) concept to support manned Mars in -flight and on electromechanical delay, maximum voluntary MAUWALYA, V. 5. surface operations contraction, and rate of force development Effect of increased acceleration on lung expansion in [AAS PAPER 87-2341 p60 A90-16533 [AD-A2133161 p51 N90-13028 dogs - Prone vs. supine body positions MINKINA. N. A. MACELROY, R. 0. p 33 A90-155M1 Characteristics of the response of animals belonging Life sciences and space research XXlll(3): Natural and MAY, RICHARD 0. to various typological groups to high-frequency and ar%ficiaIecosystems: Proceedings of the Topical Meetings Automation of fitness management for extended space microwave electromagnetic radiation p 34 A90-15638 of the 27th COSPAR Plenary Meeting, Espoo. Finland, missions MIURA, H. July 18-29, 1988 p57 A90-15426 [AAS PAPER 87-2391 p46 A90-16538 Active vibration control for flexible space environment Carbon balance and productivity of Lemna gibba, a MCCAIN, HARRY 0. use manipulators p60 A90-16522 candidate plant for CELSS p 58 A90-15430 The Fliiht TelerObOtic SeNiCW- NASA's fNSt operatinal MIYATA, YASUO Waste recycling issues in bioregenerative life support space robot A study on culturing modules for CELSS in lunar base p59 A90-15434 [ IAF PAPER 89-0501 p54 A90-13277 [ IAF PAPER 89-5761 p56 A90-13615 Effect of iodine disinfection products on higher plants MCCORMACK, PERCIAL D. MIYAZAKI, KAZUO p29 A90-15438 Long-term exposure to zerog and the gastrc-intestinal Ppplication of tubular photo-bioreactor system to culture MACELROY, ROBERT D. tract function spirulma for gas exchange and food production in Productivity and food value of Amaranthus cruentus [IAF PAPER 89-5691 p37 A90-13610 CELSS under non-lethal salt stress p 30 A90-15440 MCCULLY, LEN [IAF PAPER 89-5771 p 58 A90-13616 MACHO, L The spousal factor in pilot stress p 52 A%-1 3747 MODELL, MICHAEL Effect of space flights and hypokinesiaon plasma insulin MCKEE. S. D. The role of computerized modeling and simulation in levels and insulin receptors in rat liver Using computer graphics to design Space Station the development of life support system technologies [ IAF PAPER 89-5641 p 23 A90-13607 Freedom viewing p 59 Ago-15439 MACKIN, THOMAS J. [IAF PAPER 890931 p56 A90-13306 MONEY, K. E. Wrist orientation effect on grip strength and MEDVEDEVA. M. V. Otolith-spinal reflex testing on Spacelab-l and D-1 endurance Accumulation of the biological effects of miwowaves p43 A90-15495 [PB89-2009351 p61 N90-12179 as displayed in the behavior, the physical efficiency. the MONTGOMERY, NOEL D. MACLER, 0. body-mass increase. and the condition of cerebral Base level management of radio frequency radiation Effect of iodine disinfection products on higher plants neurons p 33 A9O-15637 protection program p29 A90-15438 MEI, LEI [ADA2117871 p48 N90-12171 MACLER, 0. A. A report of ground results for brain function experiments Base level management of radio frequency radiation Carbon balance and productivity of Lemna gibba. a in space protection program candidate plant for CELSS p 58 A90-15430 [IAF PAPER 89-5901 p 38 A90-13624 [AD-A211759] p 49 N90-13017 MACLER, BRUCE A. MEL'NIK, S. G. MONTUFARSOLIS,D. Productivity and food value of Amaranthus cruentus The effect of occupational work load on the functional Continuing studies of 'CELLS flight hardware under non-lethal salt stress p 30 A90-15440 state of naval-aviation flight personnel p32 A90-15497 MAHMOOD, MUBASHAR p41 A90-14425 MOORE, J. Decreased swelling pressure of rat nucleus pulposus MELESHKO. GI. Continuing studies of 'CELLS flight hardware associated with simulated weightlessness Ultrastructural and growth indices of Chlorella culture p 32 A90-15497 p31 A90-15485 in multicomponent aquatic systems under space flight MORALES, S. T. MAI, JEFF conditions p27 A90-15063 Occupational injuries suffered by flight attendants while The role of computerized modeling and simulation in MELIDI, N. N. on board p 41 A90-13746 the development of life support system technologies Changes in kdney response to ADH under hypogravity MORGAN, DON W. p59 A90-15439 - Rat models and possible mechanisms Prediction of thermal stress casualties MAKSIMOVA. E. N. p30 A90-15482 [ADA2123561 P50 NQO-13022 Effects of prolonged exposure of lettuce seeds to HZE MENNIGMANN, HORST-DIETER MORI. KEI particles on orbital stations p 26 A90-15058 Response of unicellular organisms to the condMns in Design for a bioreactor with sunlight supply and MALACINSKI, 0. M. low earth orbit operations systems for use in the space environment The amphibian egg as a model system for analyzing [IAF PAPER 89-6101 p24 A90-13638 p59 A90-15444 gravity effects p 28 Am-15074 MORRIS, AILENE MEREDITH, BARRY D. MANGUN, 0. R. The time required for U.S. Navy fighter pilots to shift Statin accommodationof life sciences in support Electrophysiological studies of visual attention and Space gaze and identi near and far targets of a manned Mars mission resource allocation p41 A90-13740 [AAS PAPER 87-2331 p35 A90-16532 [ AD-AZl 22871 p 53 N90-13030 MORRIS, CARLTON E. MANIE, S. MERGENHAGEN, DIETER Utilization of meet potatoes in controlled ecological life Study of activation of human peripheral blood The expression of a circadian rhythm in two strains of support systems (CELSS) p 58 A90-15429 mononuclear cells alter a space fliht Chlamydomonas reinhardii in space p 29 A90-15083 MORROW, ROBERT C. [IAF PAPER 89-61 11 p24 A90-13639 MERGENHAGEN, ELKE Utilization of white potatoes in CELSS MANO, TADAAKI The expression of a circadian rhythm in two strains of p58 A90-15431 Telescience testbed for physiological experiments Chlamydomonas reinhardii in space p 29 A90-15083 MORUKOV, 0. V. [IAF PAPER 890341 p 37 Am13267 MERKYS, A. J. Calcium ho~eOstasisin prolonged hypokinesia MARCUS, J. T. Evaluation of ewperiments involving the study of plant p 43 A90-15492 Influence of gravitoinertial force on vestibular nystagmus orientation and growth under different gravitational Microgravity-inducedchanges in human bone strength in man observed in a centrifuge p 42 A90-15078 conditions p25 A90-15053 D 43 ASO-15493

B-6 PERSONAL AUTHOR INDEX POL, DANIEL

MOUNT, F. E. NIKITINA, V. N. OLSEN. R. G. Using computer graphics to design Space Station Characteristics of the response of animals belonging Radio frequency (13.56 MHz) energy enhances Freedom viewing to various typological groups to high-frequency and rewarming from mild hypothermia [IAF PAPER 89-0931 p 56 A90-13306 microwave electromagnetic radiation p 34 A90-15638 [APA212703] p 50 N90-13024 MUCCIO. JAMES D. NlNOMlYA, KEIKEN OMAN, C. M. Space Station Freedom crew training A new method for autonomws retrieval of a satellite Yaw sensory rearrangement changes pitch responses [IAF PAPER 89-0981 p51 A90-13308 using a visual sensf and a manipulator [IAF PAPER ST-89-0121 p 40 A90-13727 MURAKAMI. DEAN M. [IAF PAPER 89-041I p 54 A90-13272 OMASA, K. Gravitational biology and the mammalian circadian NISHIZAKI, SHINJI A foodlnutrient supply plan for lunar base CELSS timing system p 29 A90-15085 A study on culturing modules for CELSS in lunar base [IAF PAPER 89-5791 p58 A90-13618 Temperature regulation in rats exposed to a 2 G field [IAF PAPER 89-5761 p56 A90-13615 ORLOV, 0.1. p 32 A90-15499 NIlTA, K. Calcium homeostasis in prolonged hypokinesia MUSACCHIA, X. J. A foodlnutrient supply plan for lunar base CELSS p43 A90-15492 Biochemical and histochemical ObseNatiOnS of vastus [IAF PAPER 89.5791 p56 A90-13618 ORLOVSKII, A. A. Effect of ultrahighdose ionizing radiation on the content medialis from rats Rown in Cosmos 1887 (experiment NITTA, KElJl KW) p31 A90-15484 of cathecholamine mediators in various regions of the rat The basic health care system for the crew lunar base brain p 34 A90715641 MYHRE, K. [IAF PAPER 89-5731 p38 A90-13612 Reduced systolic blood pressure elevations during OSER, H. Study on the nitrogen fixation system required for plant Life sciences and space research XXIII(5) - Gravitational maximum exercise at simulated altitudes culture in a lunar base p 40 A90-13738 biology; Proceedings of the Topical Meeting and [IAF PAPER 89-5751 p56 A90-13614 Workshops XVll and XVlll of the 27th COSPAR Plenary Application of tubular photo-bioreactor system to culture Meeting, Espoo, Finland, July 18-29. 1988 N spirulina for gas exchange and food production in p 25 A90-15051 CELSS OTSUBO. KOJl [IAF PAPER 89-5771 p 56 A90-13616 NADAREISHVILI. K. SH. Application of tubular photo-bioreactor system to culture Radioprotective effects of ATP and ADP on Closed and continuous algae cultivation system for food spirulina for gas exchange and food production in membranebound enzymes p33 A90-15635 production and gas exchange in CELSS CELSS p60 A90-15445 [IAF PAPER 89-5771 p56 A90-13616 NAGANO. J. NORSK, PETER Closed and continuous algae Cultivation system for food Difference in cardiovascular responses to blood pooling production and gas exchange in CELSS patterns between LBNP and head up tilting stimulated after Central venous pressure in humans during short periods of weightlessness p 44 A90-15504 p 60 A90-15445, supine cycling in women p45 A90-15509 NAGANO, JUNK0 NOTTELMANN. F. Increasing central blood volume with headdown tilting The next40 years in space - Aspects of human factors P would inhibit water intake during mild pedaling at 25 C in space research and 35 C room temperatures in woman [IAF PAPER 89-0911 p 37 A90-13304 PAABO, MAYA p45 A90-15510 NUMAGUCHI, TORU Synergistic effects of nitrogen dioxide and carbon dioxido NAKAMURA. TAlCHl Study on the nitrogen fixa'jon system required for plant following acute inhalation exposures in rats Development of the 2nd generation space robot in culture in a lunar base [PB89-2147791 p35 N90-12150 NASDA [ IAF PAPER 89-5751 p 56 A90-13614 PAN, XIAOWU [IAF PAPER 89-0511 p54 A90-13278 Changes in circadian rhythm of multiple hormones and NAKATANI, ICHIRO their relationship with individual susceptibility in simulated A new method for autonomws retrieval of a satellite 0 weightlessness p 37 A90-136013 using a visual sensor and a manipulator [ IAF PAPER 69-5651 OBRIEN, K. [IAF PAPER 89-041 ] p 54 A90-13272 PAPAT, F. Galactic cosmic radiation exposure and associated NARRAWAY, J. Plasma ANF concentrations during head-down bed rest health risks for air carrier crewmembers of various duration (from several hours to one month) - Fertilization of frog eggs on a sounding rocket in p4t A90-13745 space p28 A90-15076 Role of LBNP countermeasure p 44 A90-15503 ODONNELL, JOHN PARIS, F. NECITAILO, G. S. Design guidelines for accommodation of robotic and The next 40 years in space ~ Aspects of human factors Formation and growth of callus tissue of Arabidopsis manipulative devices on Space Station Freedom in space research under changed gravity p25 A90-15055 [IAF PAPER 89-0841 p55 A90-13300 [IAF PAPER 89-0911 p 37 A90-13304 NEDUKHA, E. M. OBRIEN, ROBERT PARKER, IAN Cell mechanisms of adaptation to main factors of space Air Force flight feeding. Volume 1: Evaluationof current Robotics and teleoperstion p60 A90-16352 Right system and alternative concepts PARRISH, JOSEPH [IAF PAPER 89-6061 p23 A90-13634 [AD-A212789] p63 N90-13043 Design guidelines for accommodation of robotic and Calcium gradient in plant cells with polarized growth in ODA, MlTSUSHlGE manipulative devices on Space Station Freedom simulated microgravity p 26 A90-15056 Development of the 2nd generation space robot in [IAF PAPER 89-0841 p 55 A90-13300 Long clinostation influence on the localization of free NASDA PATAT, F. and weakly bound calcium in cell wslls of Funaria [IAF PAPER 89-051 I p54 A90-13278 Effect on the cardiac function of repeated LBNP during hygrometrica moss protonema cells p 27 A90-15064 OGANOV, V. S. a one month head down tilt NEFF. A. W. Microgravity and musculoskeletal system of mammals [IAF PAPER 89-5931 p 38 A90-13625 The amphibian egg as a model system for analyzing p25 Am-15052 PELCAK, 0. gravity effects p 28 A90-15074 OGAWA, K. H. Pilot performance is increased after alternating hype- Subcellular components of the amphibian egg - Insights Significance of light and social cues in the maintenance and hypergravity states p45 A90-15511 provided by gravitalional studies p 28 A90-15075 of temporal organization in man p 45 A90-15512 PERBAL, 0. NELSON, THOMAS 0. OGUCHI, MlTSUO Polarily of root statocytes in space and in simulated Metacognition and retrieval from long-term memory at Application of tubular photo-bioreactor system to culture microgravity p 23 A90-13636 Mount Everest splrulina for gas exchange and food production in [IAF PAPER 89-6081 [AD-A211629] p52 N90-12177 CELSS Importance of the lgcontrols in interpreting the resulls NESLEIN, 1. L [ IAF PAPER 89-5771 p56 A90-13616 of an experiment on plant gravitropism (Biorack. 01 Reduced systolic blood pressure elevations during Closed and continuous algae cultivation system for food mission) maximum exercise at simulated altitudes production and gas exchange in CELSS [ IAF PAPER 89-6091 p 24 A90-13637 p40 A90-13738 p60 A90-15445 PETERKA, R. J. NEUBERT, J. OHLMANN, THEOPHILE Agarelated changes in human posture control: Motor Light microscopic analysis of the gravireceptor in Psychologicalmechanisms involved in the disorientation coordination tests Xenopus larvae developed in hypogravity of pilots due to fliht conditions [ NASA-CR-1858551 p6l N90-12178 p28 A90-15081 [ETN-89-95014] p63 N90-13040 PETERSEN. 0. R. OHYA, HARUHIKO NEVZGODINA, L V. Phase separated membrane bioreactor Resuns from Design for a boreactor with sunlight supply and - B~ileffects of galactic radietion HZE particles in model system studies p A90-15447 opecations systems for use in the space environment 60 experiments on the &ita1 station Salyut 7 PETROPOULOS, A. E. p26 A90-15057 p 59 A90-15444 OKUDNIKOV, IU. N. Yaw sensory rearrangement changes pitch responses Effects of prolonged exposure of lenuce seeds to HZE Long-term experiments on man's stay in biological (IAF PAPER ST-89-0121 p40 A90-13727 particles orbital stations p26 A90-15058 on life-support system p 58 A90-15433 PUNEL, H. NEWPORT, CURT OLCOlT. T. M. Behaviour of sinale-cell oraanisms exmsed to Design guidelines for accommodathn of robotic and Innovative approached to the design of begenerative hypergravity manipulative devices on Space Station Freedom life support systems for advanced missions llAF PAPER 89-6071 D 23 A90-13635 [IAF PAPER 89-0841 p55 A90-13300 [IAF PAPER 89-0261 p54 A90-13261 PLATO, P. NICOGOSSIAN. ARNAULD OLOFF, C. Skeletal muscle antioxidant enzyme levels in rats after Effects of body poslure on the interpretation of Skeletal muscle antioxidant enzyme levels in rats after simulated weightlessness. exercise and dobutamine biomedical data obtained from manned missions simulated weightlessness, exercise and dobutamine p32 A90-15498 [IAF PAPER 89-5961 p39 A90-13628 p 32 A90-15498 POL, DANIEL NICOQOSSIAN, ARNAULD E. OLSEN. E. 1. Design guidelines for accommodation of robotic and Space physbbgy and medidne (2nd edition) The NASA SET1 sky survey: Recant developments manipulative devices on Space Station Freedom p46 A90-16625 p 64 N90-12804 [IAF PAPER 89-0841 p55 A90-13300

B-7 POLLICK, FRANK E. PERSONAL AUTHOR INDEX

POLLICK. FRANK E. REPETA, D. J. S Disaiminating rigii from nonrigid motion Evidence for anoxygenic photosynthesis from the [ADA2117941 p62 N90-12180 distribution of bacteriochlorophylls in the Black Sea SACCUZZO, DENNIS P. POLULAKH. IU. A. p24 A90-14631 The effect of incentives on the reliability and validity of Plant cell plasma membrane structure and properties RESCHKE, MILLARD F. cognitive speed tests undm dinostatting p26 A90-15061 Biochemical correlates of neurosensory changes in [ADA21 13461 p62 N90-12181 POLUUAKH, IU. A. weightlessness SACHDEV, S. S. Cell mechanisms of adaptation to main factors of space [IAF PAPER 89-5981 p 39 A90-13630 Requirements and concepts for the Space Station flight REYNOLDS, ORR E. Remote Manipulator System [IAF PAPER 896061 p23 A90-13634 International Union of Physiological Sciences [IAF PAPER 89JX91 p55 A90-13289 POOL, SAM Commission on Gravitational Physiology, Annual Meeting. SALE, D. 0. Effects of body posture on the interpretation of 10th. Montreal, Canada, Oct. 9-14, 1988. Proceedings The effect of concurrent strength and endurance training biomedical data obtained from manned missions p 42 A90-15477 on electromechanical delay. maximum voluntary [IAF PAPER 89-5961 p 39 A90-13628 RICHAUD, CH. contraction. and rate of force development [ADA21331 61 p 51 N90-13028 POOL, SAM L The C23A - First step to a monitoring system of CELSS SALISBURY, F. 8. Space physiology and medicine (2nd din) in flight p 59 A90-15437 Current and potential productivity of wheat for a p 46 A90-16625 RICHOILLEY, G. Behaviour of singlecell organisms exposed to controlled environment Me suppott system PopOVA, A. F. p 57 A90-15427 Cell mechanisms of adaptation to main factors of space hypergravity [IAF PAPER 89-6071 p23 A90-13635 SANN, P. A. tiiht Human factors and productivity on Space Station [IAF PAPER 89-6061 p 23 A90-13634 RIEDEL, U. Freedom Ultrastructural and growM indices of Chlorella culture Studies on Habitation Module and interconnecting [IAF PAPER 89-0871 p 55 A90-13301 in multicomponent aquatic systems under space tiiht elements for a future European space statin SAUER, R. conditions p27 A90-15063 [IAF PAPER 890921 p55 A90-13305 Effect of iodine disinfection products on higher plants POPOVIC, VOJlN RIPKENS, MICHAEL p 29 A90-15438 Plasma stress hormones in resting rats . Eighty fwr Studies on predicting the resynchronization of the SAVAGE, P. D.. JR. day study p32 A90-15489 circadian system after transmedian flights The rodent research animal holding facility as a barrier POTTIER, J. [DNLR-FB-89- 101 p48 N90-12172 to environmental contamination Effect on the cardiac function of repeated LBNP during RITZENTHALER, J. D. [NASA-TM-102237] p35 N90-12151 a one month head down tilt Subcellular components of the amphibian egg - Insights SCHAFFAR. L [IAF PAPER 89-5931 p 38 A90-13625 provided by gravitational studies p 28 A90-15075 Study of activation of human pecipheral blood PWZ, BERNARD J. ROBINSON, PATRICK mononuclear cells after a space flight Individual differences. mission parameters. and Three dimensional object recognition employing [ IAF PAPER 89-61 1 ] p 24 A90-13639 spaceflight environment habitability combined visual and tactile sensing SCHATZ, A. [AAS PAPER 87-2401 p6l A90-16539 [PB89-2194891 p52 N90-12176 Gravity and the membranesolution interface - PYTEL, JEAN LANDA ROCK, PAUL 8. Theoretical investigations p 26 A90-15059 Wrist orientation effect on grip strength and Propranolol and the compensatorycirculatory responses Lght microscopic analysis of the gravireceptor in endurance to orthostasis at high altitude p 40 A90-13736 Xenopus lawae developed in hypogravity I [PE89-2009351 p61 N90-12179 The effect of caffeine on endurance time to exhaustion p 28 A90-15081 at high altitude SCHELD, H. W. [AD-A212069] p47 N90-12163 Thin film bioreactors in space p 27 A90-15068 SCHMIDT, E. Q ROSE, MADELINE S. The effect of caffeine on endurance time to exhaustion Modular ABR system testbed for development and implementationof automation and robotics elements within QIAN, JINKANG at high altide future orbital systems Experimental research on the applicabilities of Chinese [ADA2120691 p47 N90-12163 [IAF PAPER 890361 p 54 A90-13269 medicine to space medicine ROSENBAUM, J. F. [IAF PAPER 89-6011 p39 Am-13633 SCHOPPERS, MARCEL Subcellular components of the amphibian qg - Insights Telerobotic control for teams of semi-autonomous provided by gravilational studies p 28 A90-15075 agents. phase 1 ROSENZWEIG. EYAL [ADA21 16481 p62 N90-13037 R Geotropic sensitivity of hornets p 27 A90-15072 SCHWARlZ, ROBERT S. ROSENZWEIG, OFER Gravitational influence on systemic arterial dynamics RADEMACHER, STEVEN E. Geotropic sensitivity of hornets p 27 A90-15072 using a 3-element Windkessel model p 44 A90-15506 Base level management of radio frequency radiation ROTKOVSKA. D. Regional aortic pressure apparent phase velocity in the protection program Increasing the radioresistance of mice with ivastimul baboon during 70 degree tilt p44 A90-15507 [ADA21 17871 p48 N90-12171 p33 A90-15636 SCHWARTZKOPF, S. H. Base level management of rado frequency radiation ROUSE, DORIS J. Innovative approaches to the design of bioregenerative protection program NASA spinoffs to bioengineering and medicine life support systems for advanced missions [AD-A211759] p49 N90-13017 [IAF PAPER 89-6831 p 40 A90-13673 [IAF PAPER 89-0261 p54 A90-13261 I RADKOVSKI, G. ROVICK, ALLEN SEBASTIAN, L A. Psycho-physiological studies during the flight of the Computer generation of a tutorial dialogue Effectsof simulatedweightlessness and sympathectomy second Bulgarian cosmonaul [ADA2119761 p46 N90-12162 on maximum V02 of male rats p32 A90-15491 [IAF PAPER 89-5861 p38 A90-13621 ROWE, JOSEPH SEDDON, RHEA M. RAHMAN, Z USSR Space Life Sciences Digest. Issue 24 Space Station accommodationof liesciences in support of a manned Mars mission Effects of simulated weighlessnessand sympathectomy [NASA-CR-3922(28)-ISSUE-24] p 35 N90-12152 on maximum V02 of male rats p32 A90-15491 [AAS PAPER 87-2331 p35 A90-16532 USSR Space Life Sciences Digest, Issue 22 RAKLEVICIENE, D. P. SEKI, YOlCHl [NASA-CR-3922(26)-ISSUE-22] p 35 N90-12153 Evaluation of experiments involving the study of plant A study on culturing modules for CELSS in lunar base orientation and growth under different gravitational USSR Space Life Sciences Digest. Iwe23 [IAF PAPER 89-5761 p56 A90-13615 conditions p 25 A9015053 [NASACR-3922(27)-lSSUE-23] p 36 N90-12154 SELEZNEV, SERGE1 A. RAPPAPORT, CATHERINE ROYLAND, JOYCE E. How did the first cells appear? p 63 A90-18035 Investigation of resonant acdc magnetic field effects The effect of suspension on nicotinic acetylcholine SEROVA, L [ ADA21 1612 1 p 37 N90-12159 receptor number and affinity at the rat neuromuscular Effect of space flights and hypokinesiaon plasma insulin RASCH. W. junction p31 A90-15483 levels and insulin receptors in rat liver I Reduced systolic blood pressure elevations during ROZHDESTVENSKII, L M. [IAF PAPER 89-5641 p23 A90-13607 maximum exercise at simulated altitudes Effect of ultrahighdose ionizing radiation on the content SEROVA, L V. p 40 A90-13738 of cathecholamine mediators in various regions of the rat The effect of microgravity on the reproductive function REES, CHRISTOPHER brain p34 A90-15641 of male rats p31 A90-15488 Air Force fliiht feeding. Volume 1: Evaluation of current SESHAN, P. K. RUBAL, BERNARD J. system and alternative Phase separated membrane bioreactor - Results from concepts Effects of transition from supine to upright positions on [ADA2127891 p63 N90-13043 model system studies p 60 A90-15447 central hemodynamics in patients with chest pain I REEVES, JOHN T. SEYFFER, R. syndrome p 43 A90-15490 Propranololand the compensatMyarculatory responses lnterserosal pressures and circulatory homeostasis io orihosiasis at high eltitude p40 A90-13736 Gravilational influence on systemic arterial dynamics during changes in the gravitalional inertial force REISER. M. using a 3-element Windkessel model p 44 A90-15506 environment p 42 A90-15480 Unilateral centnfugation of the otoliths as a new method Regional aortic pressure apparent phase velocity in the SEZAKI, WUO lo determine bilateral asymmetries of the otolith apparatus baboon during 70 degree tilt p 44 A90-15507 A study on culturing modules for CELSS in lunar base in man RUMMEL, JOHN D. [IAF PAPER 89-5761 p56 A90-13615 [IAF PAPER 89-5661 p37 A90-13609 Transpiration during life cycle in controlled wheat SHADIEVA, N. KH. RENOU. J. L growth p58 A90-15432 Radioprotective properties of a Co(lll) biocomplex The C23A - Erst step to a monitwing system of CELSS p 33 A90-15634 in fliht p59 A90-15437 The case for cellulose production on Mars SHAKULA, A. V. RENZETTI, N. A. [AAS PAPER 87-2321 p60 A90-16531 The effect of occupational work load on the functional The NASA SET1 sky survey: Recent developments RUOFF, CARL F. state of naval-aviation flight personnel I p64 N90-12804 Space robotics in the '90s p57 A90-14998 p41 A90-14425 PERSONAL AUTHOR INDEX UBBELS, G. A.

SHAPIRO. DANIEL STEFFEN. J. M. TAKAQI. S Telerobotic control for teams of semi-autoncmcus Biiand histochemical dxwvations of vastus Dorsal llght response and changes of its responses agents. Phase 1 medialis from rats Rarm in Cosmos 1887 (experiment under varying acceleration condiins [ ADA21 16481 p62 N90-13037 KW) p3t A90-15484 p28 A90-15080 SHAPIRO, NATHAN L STEINHAUSER, RAYMOND P. TAWASHI, Y. Recovery to +tGz and +2Gz following +Gz-induced Deep venous thrombosis in the milhary pilot Subcritical and supercritical water oxidation of CELSS loss of aM8ciousne88 - Operational considerations p41 A90-13742 model wastes p 59 A90-15436 p4t A90-13741 STEWART, JOHN C. TEETER, RONALD SHAPOSHNIKOVA, E. S Deep venous thrombosis in the military pilot USSR Space Life sciences Digest, Issue 24 Characteristia, of the response of animals belonging p4t A90-13742 [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 to various typological groups to high-frequency and STRAUCH. Q. USSR space Life sdences Digest, Issue 22 microwave electromagnetic radiation p A90-15638 34 Hemodynamicsduring head tilting lower body [NASA-CR-3922(2s)-lSSUE-22] p 35 N90-12153 SHARP, JOSEPH dorm and c. negative pegsure and pharmacological interventions for USSR Space Life Sciences Nest. Issue 23 The Life program at NASA Ames Research sciences the wuntermeasures [NASACR-3922(27)-lSSUE-23] p 36 N90-12154 Center An overview p 30 A90-15478 - [IAF PAPER 89-5971 p 39 A90-13629 TEMME, LEONARD A. SHAW, BARBARA RAMSAY The time required for US. Navy fighter pilots to shift STRUTHERS, NANCY J. Boron analogues of amino adds and derivatives Individual differences. mission parameters, and gaze and identify near and far targets [ADA211311] p 36 N90-12157 apacefliht environment habitability p41 A90-13740 TERN, M. SHEVELEV, IQOR' A. [AAS PAPER 87-2401 p61 A90-16539 Binocular depth perception and its hyperacuity in A foodlnutrient supply plan for lunar base CELSS STUMP, C. S common and specially selected subjects [IAF PAPER 89-5791 p56 A90-13618 Effects of simulated weightlessnessand sympathactomy TERN. MINORU [IAF PAPER 89-5881 p38 A90-13622 on maximum VO2 of male rats p 32 A90-15491 SHI. ZHWEN The basic health care system for the crew lunar base STUPAKOV, Q. P. Ewperimental research on the applicabilitiesof Chinese [IAF PAPER 89-5731 p 38 A90-13612 Miogravity-induced changes in human bone strength medicine to space medicine TERSKOV. 1. A. p43 A90-15493 [IAF PAPER 89-6011 p 39 A90-13633 Long-term experiments on man's stay in biological SUUYAN, FRANK M. SHIGEHARA, M. life-support system p 58 A90-15433 The biologcal clock of Neurospora in a microgravity Design evaluation of man-in-theloopcontrol system THOMPSON, B. Q. and environment p 29 A90-15082 of Japanese Ewpetimental Module Remote Manipulator Life sciences and space research XXlll(3): Natural and System Gravitational biology and the mammalian circadian artnicial ecosystems; Proceedings of the Topical Meetings of the 27th COSPAR Plenary Meeting, Espoo. Finland, [IAF PAPER 894901 p 55 A90-13303 timing system p 29 A90-15085 SUM, T. July 18-29. 1988 p 57 A90-15426 SHIMADA, ATSUHIRO Gas bubble coalescence in reduced gravity conditions Application of tubular photebioreactorsystem to culture Design and evaluation of man-in-the-loop control system of Japanese Experimental Module Remote Manipulator p 30 A90-15446 spirulina for gas exchange and food produdon in THOMPSON, JOHN F. CELSS System [IAF PAPER 894901 p55 A90-13303 A comparison of two subjectcontrolled attitude [IAF PAPER 89-5771 p56 A90-13616 measures during somatogravic illusion exposure Closed continuous algae cultivation system for food SUN, HONQYUAN and Changes in circadian rhythm of multiple hormones and [AD-A212528] p53 N90-13031 production and gas exchange in CELSS THORSTENSON, Y. p 60 A90-15445 their relationshipwith individual susceptibility in simulated weightlessness Effect of iodine disinfection products on higher plants SHIMOYAMA, 1. [IAF PAPER 89.5651 p37 A90-13608 p29 A90-15438 Active vibration control for flexible space environment THOULOUSE, J. use manipulators p60 A90-16522 SUVOROV. N. B. Accumulation of the biological effects of microwaves Biomedical payload of the French-Soviet long duration SHINDO, YUJI fliht First conclusions as displayed in the behavior, the physical efficiency, the - on nitrogen fixation system required for plant [IAF PAPER 89-5631 p 37 A90-13606 Study the body-mass increase, and the condition of cerebral culture in a lunar base TIBBllTS, T. W. neurons p33 A90-15637 [IAF PAPER 89-5751 p56 A90-13614 Life sciences and space research XXlll(3): Natural and Characteristics of the response of animals belonging SHORTANOVA, TAMARA KH. artificial ecosystems; Proceedings of the Topical Meetings to various typological groups to high-frequency and Neurochemistry of hibernation in mammals of the 27th COSPAR Plenary Meeting. Espoo. Finland, microwave electromagnetic radiation p 34 A90-15638 p34 A90-16057 July 18-29. 1988 p 57 A90-15426 SUZUKI, Y. SIWRENKO, P. Q. TlBBllTS, THEODORE W. Differencein cardovascular responses to blood pooling Prospects of studies in space phytobiology Utilization of white potatoes in CELSS patterns between LBNP and head up tilting stimulated after [IAF PAPER 89-5781 p23 A90-13617 p58 A90-15431 supine cycling in women p45 A90-15509 SIMPSON, D. J. TIRRE, WILLIAM C. SUZUKI. YOJl Evidence for anoxygenic photosynthesis from the Individual differences in associative learning and Increasing central blood volume with headdown tilting distribution of bacteriochlorophyllsin Black Sea forgetting the would inhibit water intake during mild pedaling at 25 C p24 A90-14631 [ADA2127651 p 54 N90-130% and 35 C room temperatures in woman TIXADOR, R. SIROTA, M. Q. p45 A90-15510 Eehaviour of single-cell organisms exposed to of space adaptation syndrome in experiments Studies SVABOVA, E. hypergravity on primates pertwed on board of Soviet biosatellite Effect of space fliihts and hypokinesia on plasma insulin [IAF PAPER 89-6071 p23 A90-13635 'Cosmos-1887' p32 A90-15494 levels and insulin receptm in rat liver TOMI, L M. SMA-NE. PHILIP Q. [IAF PAPER 89-5641 p 23 A90-13607 Otolith-spins1 reflex testing on Spacelabl and 0-1 Automation of fitness management for extended space p43 A90-15495 missions SVEQZDIENE, D. V. Evaluation of experiments involving the study of plant TORIKOSHI, 5. [AAS PAPER 87-2381 p46 A90-16538 Orientation and growth under different gravitational Difference in cardiovascular responses to Mood pooling SMERNOFF, D. T. conditions p25 A90-15053 patterns between LBNP and head up tilting stimulated aftw Carbon balance prodwtivity of Lernna gibba. a and SWANSON, QEORGE D. supine cycling in women p45 A90-15509 candidate plant for CELSS p 58 A90-15430 Exercise strategies and aasessment of cardorespiratory TORIKOSHI, SHIQEYO SNOW. M. H. L fitness in space Increasing central blood volume with head-down tilting Early development in the mouse - Would it be affected [MSPAPER 87-2381 p 46 A90-16535 wouM inhw water intake during mild pedaling at 25 C 35 C room temperatures in woman by micrograw p28 A90-15077 SYCHEV, V. N. and SNYDER, L Ultrasbuctural and growth indii of Chlorella culture p45 A90-15510 Galactic cosmic radiation exposure and associated in multicomponent aquatic systems under space flight TORUA, R. A. Prevention of radiation sickness, induced by low-level health risks for air canier crewmembers condiis p27 A90-15063 ionizing radiation, by repeated injeclions with increasing p41 A90-13745 SYKORA, J. SOLCOVA, 1. doses of chemii radioprotectors p 33 A90-15633 Pilot performance is increased after alternating hypo- TRAD, LAURIE A. Pilot perfonname is iweaaed after alternating hypo- and hypergravity states p45 A90-15511 and hypergravity states p45 A90-15511 propranololand the compensatory drculatory responses SYTNlK. K. Y. to wthostasis at high altitude p40 A90-13736 SOLENOV, E. 1. Cell mechanisms of adaptation to main factors of space Change8 in Mney response to ADH under hypogravity The effect of caffeine on endurance time to exhaustion Riht at high altitude - Rat models and possible mechanisms [IAF PAPER 89.6061 p 23 A90-13634 p 30 A90-15482 [ ADA2120691 p47 N90-121C3 Calcium gradient in plant cells with polarized growth in TREMOR, J. SPERUNQ, QEOROE simulated microgravity p 26 A90-15056 Sources and processing of CELSS wastes Visual motion perception Ultrastructural and growth indices of Chlorella culture D 59 A90-15405 [ADA210994] p46 N90-12160 in multicomponent aquatic systems under space flight Three stages and two systems of visual processing condiins p 27 A90-15063 [ ADA2126701 p53 N90-13032 SPIELVOOEL BERNARD F. U Boron analogues of amino acids and derivatives T UBBELS, 0. A. [ADA2113111 p36 N90-12157 Life sciencesand space research XXIII(5) - Gravitational STEENEKEN, H. J. M. TAKABAYASHI, A. biology; Proceedings of the Topical Meeting and Application of active noise reduction for hearing Dorsal light response and changes of its responses Workshopg XVll and XVlll of the 27th COSPAR Plenary proteclhn and speech intelligibility improvement under varying acceleration conditions Meeting, Espoo, Finland, July 1629,1988 [IZF-198&21] p63 N90-13042 p 28 A90-15080 D25 A90-15051

B-9 UCHAKIN, P. N. PERSONAL AUTHOR INDEX

Developmental biology in space - Why and how? The case for cellulose produclhn on Mars WILEY, ROGER W. p 27 A90-15070 [AAS PAPER 87-2321 p60 A90-16531 Visual acuity and stereopsis with night vision goggles Fertiliation of frog eggs on a sounding rocket in VOLODIN, V. P. [AD-A211552] p47 N90-12167 space p 28 A90-15076 Prediing the postradiative radiosensitivity of mammals WILKENS, TED A. UCHAKIN. P. N. and man according to the LO50 criterion after acute Effects of transition from supine to upright positions on Immunocompetent cells producing humoral mediators external irradiation p 34 A90-15639 central hemodynamics in patients with chest pain of bone tissue mineral metabolism during space fliht VON BAUYGARTEN, R. syndrome p43 A90-15490 simulation p 43 A90-15496 Influence of proprioceptive information on space WILKES. ROBERT L orientation the ground in wbital UEDA, YASUFUYI on and weightlessness Microcomputer-besed tests for repeated-measures: Oxygen separation system of residentjal space at the p42 A90-15079 Metric properties and predictive validities Dorsal liiht response and changes of its responses lunar base [NASA-CR-185517] p 52 N90-12174 [IAF PAPER 89-5741 p56 A90-13613 under varying acceleration conditions A menu of self-administered microcomputer-based p 28 A90-15080 UENOHARA, Y. neurotoxicology tests VON BAUYGARTEN. R. J. [ NASA-CR-1855181 p 52 N90-12175 Active vibration control for flexible space environment Unilateral centsifugation of the otoliths as a new method use manipulators p60 A90-16522 to determine bilateral asymmetries of the otoli apparatus WILLSHIRE, KELLI F. Space Station accommodationof life sciences in support UGOLEV, A. Y. in man Biophysical principles of the effects of cosmic rays and [IAF PAPER 89-5661 p37 A90-13609 of a manned Mars mission radiation from accelerators p 34 A90-18047 [AAS PAPER 87.2331 p35 A90716532 UNGS. TIMOTHY J. WINFIELD, DANIEL L The occurrema of the vection’illusion among heliter W NASA spinoffs to bioengineering and medicine pilots while flying over water p 52 A90-13743 [IAF PAPER 89-8833 p40 A90-13673 UR’IASH, V. V. WADE, TED D. WINGET, C. M. Accumulation of the biological effects of microwaves Automation of fitness management for extended space Significance of liht and social cues in the maintenance as displayed in the behavior, the physical efficiency, the missions of temporal organization in man p 45 Ago-15512 body-mass increase, and the condition of cerebral [AAS PAPER 87-2391 p46 A90-16538 WOOD, E. H. neurons p 33 A90-15637 WAKEFIELD, GREGORY H. Interser0881 pressures and circulatory homeostasis UTTAL, WILLIAM R. Timefrequency factors in auditay perception during changes in the gravitational inertial force Teleoperators p 60 A90-15800 [ADA21 14911 p 49 N90-13018 environment p 42 A90-15480 WALL, C., 111 WOODMAN, C. R. Yaw sensory rearrangement changes pitch responses Effects of simulatedweightlessness and sympathectomy V [IAF PAPER ST-894121 p40 A90-13727 on maximum VO2 of male rats p 32 A90-15491 WANG, BAOZHEN WRAY, A. E. VACEK. A. Experimental research on the appliiilis of Chinese The rodent research animal holding facility as a barrier Increasing the radioresistance of mice with ivastimul medicine to space medicine to environmental contamination [IAF PAPER 89-601 ] p39 A90-13633 p 33 A90-15636 [NASA-TM-102237] p 35 N90-12151 VALVERDE, J. R. WANG, D. WYDEVEN, T. Insects as test systems for assessing the potential role Waste recycling issues in bioregeneratie life support Souroes and processing of CELSS wastes of microgravity in biological development and evolution p59 A90-15434 p 59 A90-15435 p27 A90-15071 WATANABE. S. Subcritical and supercritical water oxidation of CELSS VAN HOLTEN, C. R. Dorsal light response and changes of its responses model wastes p59 A90-15436 Influence of gravitoinertial force on vestibular nystagmus under varying acceleration conditions in man ObSeNed in a centrifuge p 42 A90-15078 p 28 A90-15080 VANRAAIJ, J. L WATANABE, SATORU Y Pre- and postflight postural control of the D1 Spacelab Telesciema testbed for physiological experiments mission astronauts examined with a tilting room [IAF PAPER 89-0341 p 37 A90-13267 YABUKI, K. [ IZF-1988-251 p N90-13039 63 WATT, D. G. D. Plant cultural system incorporated into CELSS VANVELDEN, J. 0. Otolith-spinal reflex testing on Spacelab-1 and D1 [ IAF PAPER 89.5801 p 57 A90-13619 Application of active noise reduction for hearing p43 A90-15495 protection and speech intelliiibili improvement YAMADAYA, SYOKO WEBER, L J. Study on the nitrogen fixation system required for plant [IZF-1988-21] p63 N90-13042 The effect of suspension on nicotinic acetylcholine VARSI, GlULlO culture in a lunar base receptor number and affmity at the rat neuromuscular [IAF PAPER 89-5751 p56 A90-13614 Advances in space robotics junction p31 A90-15483 [IAF PAPER 894521 p 55 A90-13279 YAYAMOTO. HIROYASU VASILEVSKII, N. N. WEINBERG, R. P. Oxygen separation system of residential space at the Accumulation of the biological effects of microwaves Effects of serial wetdry-wet cold exposure: Thermal lunar base balance, physical activity, and cognitive performance as displayed in the behavior. the physical efficiency, the [IAF PAPER 89-5741 P56 A90-13613 body-mass increase, and the condition of cerebral [AD-A212704] p51 N90-13025 YAMASHITA, YASAMICHI neurons p33 Am-15637 WEINBEROER, NORMAN Y. Telescience testbed for physiological experiments VASSAUX, D. Adaptive information processing in auditory cortex [IAF PAPER 894341 p 37 A90-13287 [AD-A2112941 p47 N90-12166 Biomedical payload of the French-Soviet long duration YAYAWAKI, K. flight. First conclusions WEISBRODE, S. Design and evaluation of man-in-thaloopcontrol system [IAF PAPER 89-5631 p37 A90-13606 Modifications of bone atrophy seen with hindlimb of Japanese Experimental Module Remote Manipulator VERNIKOSDANELLIS, J. suspension by exercise and dobutamine System Carotid baroreflex response following 30 days exposure p31 A90-15487 [IAF PAPER 894901 p55 A90-13303 to simulated microgravity p 44 A90-15502 WETZIG, J. YAMAZAKI, SHOJI VERNIKOSDANELLIS, JOAN Unilateral centrifugation of the otoliis as a new method A study on culturing modules for CELSS in lunar base The Life Sciences program at the NASA Ames Research to determine bilateral asymmetries of the otolith apparatus [IAF PAPER 89-5761 p56 A90-13615 Center - An overview p 30 A90-15478 in man YOKOUWA, K. VERNOS. 1. [IAF PAPER 89-5861 p37 A90-13609 Difference in cardiovascular responses to blood pooling Insects as test systems for assessing the potential role Life sciences and space research MlIl(5) - Gravitational patterns between LQNPand head up tilting stimulated after of microgravity in biological development and evolution biology; Proceedings of the Topical Meeting and supine cycling in women p45 A90-15509 p 27 A90-15071 Workshops XVll and XVlll of the 27th COSPAR Plenary YOKOUWA, KIKUKO VICKERS, ROSS R., JR. Meeting. Espoo, Finland, July 18-29. 1988 Increasing central blood volume with headdown tilting Demonstration of replicable dimensions of health p25 A90-15051 would inhibit water intake during mild pedaling at 25 C behaviors Influence of proprioGeptive information on space [ADA21 19201 p46 N90-12161 and 35 C room temperatures in woman orientation on the ground and in orbital weightlessness p 45 A90-15510 VICO, L p 42 A90-15079 YOUNG, PATRICIA M. Normalisation of bone cellular responses occurs Dorsal liht response and changes of its responses between 7 and 14 days of simulated weightlessness in The effect of caffeine on endurance time to exhaustion under varying acceleration condtions at high altitude rats p 31 A90-15486 P 28 A90-15080 VOQE, V. [ADA2120691 p47 N90-12163 M. WHEELER, JEFFREY J. Probable bends at 14,000 feet - A case report p41 A90-13744 Membrane fusion: The role of poIyphosphaWylinosito1 [ADA2112891 p36 N90-12156 VOGEL. ti. z Influence of proprioceptive information on space WHINNERY, JAMES E. orientation on the ground and in orbital weightlessness Recovery to +1Gz and +2Gz following +Gz-induced ZHADKO, S. 1. p42 A90-15079 loss of consciousness - Operational considerations Prospects of studies in space phyiobiology VOLK, T. p41 A90-13741 [ IAF PAPER 89-5781 p23 A90-13617 Life sciences and space research XXlIl(3): Natural and WHITMAN. RUTH 1. Plant cell plasma membrane structure and properties attifMl ecosystems: Proceedingsof the Topical Meetings The Fliht Telerobotic Seriicer - NASA’s first operational under clinostatting p26 A90-15061 of lhe 27th WSPAR Plenary Meeting, Espoo, Finland, space robot ZHANO, GUANMING July 1&29,1988 p 57 A90-15426 [IAF PAPER 89-0501 p54 A90-13277 Changes in circadian rhyihm of multiple hormones and VOLK, TYLER WICKYAN, LESLIE A. their relationship with individual susceptibility in simulated Transpiration during life cycle in controlled wheat The effects of automation on work in space weightlessness growth p 58 A90-15432 [ IAF PAPER 89-5831 p 57 A90-13620 [IAF PAPER 89-5651 p 37 A90-13608

6-10 ~

PERSONAL AUTHOR INDEX ZORAD, S. I ZHANG, RUIJUN Experimental research on lhe applicabilities of Chinese mediine to space medicine [IAF PAPER 89-601 I p39 Am-13633 ZIEQLER, JAN i Life beyond gravity p45 AQO-16299 I ZORAD, S Elfedof apace flights and hypokinesia on plasma insulin 1 levels and insulin receptom in rat liver I [IAF PAPER 885641 p23 AS13607

B-11 CORPORATE SOURCE INDEX

AEROSPACE MEDICINE AND BIOLOGY /A Continuing Bibliography (Supplement 334) March 1990

Army Rnoarch lMt of Environmental MOdlClm., D Typical Corporate Source Natlck, MA. The effect of caffeine on endurance time to exhaustion Defmand CMI Imt. of Envlronmontal Msdlclne, Index Listing at high altnuda Downrvlew (Ontarlo). [ADA2120691 p47 N90-12163 Otolith-spinal reflex testing on Spacelabl and D1 Heatstroke pathophysiology: The energy depletion p43 A90-15495 model The effectof concurrent strength and endurance training CORPORATE SOURCE [ADA2121561 p47 N90-12164 on electromechanical delay. maximum voluntary Human body regional convective heat transfer contraction. and rate of force development determination using sublimating naphthalene disks [ADA2133161 p 51 N90-13028 [ADA2121701 p47 N90-12165 Dwbche Fonchungr und Vanuchaanstslt fuer Lufl., und Raumfahfi, Cologne (Gemuny, FA.). Heat exhaustion 7Blonetlcs Corp., Cocoa Beach, FL. Studies on predicting the resynchronization of the [ADA212128] p49 N90-13014 A simple. mass balance model of carbon flow in a circadian system after transmedian flights controlled ecological life support system Exertional heatstroke: An international perspective. An LDFVLR-FB-69-10] p 48 N90-121'72 [NASA-TM-102151] p 20 N90-10571 introduction: The role of exercise in the etiology of Deutuhe FOrSChungMMtak fuar Lufl- und Raumfahit, exettional heatstroke Cologne (Gemuny, F.R.). -----i-/---1[AD421 22421 p50 N90-13020 r Biochemical and physiological changes in glider pilots Aspen Technology. Inc.. Cambrldge, MA. during multihour flights The role of computerized modeling and simulation in [ DLR-FB-69-29] p49 N90-13018 the development of life support system technologies Effects of a time zone shift of nine hwrs on the circadian p59 A90-15439 rhythms in cockpit aircrew members on longhaul flilrts Auburn Unk., AL [DLR-FB-69-31] p49 N90-13019 Prowsal for a zero-aravitv-. toilet faflliw for the =ace Duke Unlv., Durham, NC. station Boron analcgues of amino acids and derivatives Listings in this index are arranged alphabetically [NASACR-183151] p62 N90-13036 [AD-A211311] p 36 N90-12157 by corporate source. The title of the document is used to provide a brief description of the subject matter. The page number and the accession B E number are included in each entry to assist the Blondla Corp.. cocoll Beach, FL Ewle Natlo~leSuperleure der Telbcommunlcatlonu, user in locating the abstract in the abstract section. Changes of muscle function and size with bedrest Paris (France). If applicable, a report number is also included as p43 A90-15501 State of the art of humanlmachine dialog tool an aid in identifying the document. Booz-Allen and Hmllton, Inc., Rerton, VA. prototypes Space Station Freedom crew training [TELECOM-PARIS89-H001] p 62 N90-13038 [IAF PAPER 894981 p51 A90-13308 Emory Univ., Atlanta, GA.

Plasma stress hormones in resting rats ~ Eighty four day study p 32 A90-15489 C Eu.x Carp., Orlando. FL Microcomputer-based tests for repeated-measures: Califomla Unlv., Borkeloy. Metric properties and predictive validities A Effect of iodine disinfection products on higher plants [NASA-CR-185517] p 52 N90-12174 p29 A90-15438 Advanced Lkd.lon Syrtemo, Mwntdn Vkw, CA. A menu of self-administered microcomputer-based Unlv., Davlr Telerobotic control for teams of semi-autonomous Califomla neurotoxicology tests The biological clock of Neurospora in a microgravity agents, phase 1 [NASA-CR-185518] p52 N90-12175 [AD-A211646] p62 N90-13037 environment p 29 AW-15082 Alr FOIW Human Reao~maaLab., Brooks AFB. TX. Gravitational biology and the mammalian circadian Individual differences in associative learning and timing system p 29 A90-15065 G forgetting Temperature regulation in rats exposed to a 2 G field [ADA2127651 p54 NW-13034 p 32 A90-15499 Good Samaritan Hospltnl and Msdlcal Center, Alr FOIW lMt Of Tech., Wrlght-Pattenon AFB, OH. Califomla Unlv.. Irvlne. Portlmld, OR. A comparison of two subjectantrolled attitude Synaptic plasticity and memory formation Age-related changes in human posture control: Motor measures during somatogravic illusion exposure [ ADA21 13681 p36 N90-12158 coordination tests [ADA2125261 p53 N90-13031 Adaptive infwmation processing in auditory cortex [NASA-CR-185855] p 61 N90-12178 Alr FOIW Occupatlolul and Environmental Health Lab., [ ADA21 12941 p47 N90-12166 Brooks AFB, TX. DisMiminating rigii from nonrigid motion Base level management of radio frequency radiation [ADA2117941 p 62 N90-12180 H protection program Califmlil Unlv., La JolU [AD-A211787] p48 N90-12171 Decreased swelling pressure of rat nucleus pulposus Hamburg Unlv. (O.muny, F.R.). Base level management of radio frequency radiation associated with simulated weightlessness The expression of a circadian rhythm in two strains of Chlamydomonas reinhardii in space p 29 A90-15083 protection program p 31 AW-15485 [ADA2117591 p49 N90-13017 Califomla Unlv., Sen D1.ao. Hrlth Effects Research Lab., Remrch Trlangle Park, R.Uuch coumll, Edmonton Alb.rt. (Canada). Electrophysiological studies of visual attention and NC. Effects of atmospheric mix and toxic fumes on military Life scienc@aand space research XXlIl(3): Natural and resource allocation artiwal ecosystems;pmceeck 'ngs of the Topical Meetings [ADA2122671 p 53 N90-13030 performance of the 27th COSPAR Plenary Meeting, Espoo, Finland, [P889-2236301 p 49 N90-13015 July lE29,lW p 57 A90-15426 Califom* Unlv., Sen Fmnckc~. Thin film biaeactm in space p 27 A90-15068 Hobrow Unlv., J~NN~(lunl). Carbon balance and productivity of Lemna gibba. a Mzoru steta unhr., Twnp Anatomical study of the final common pathway for candidate plant for CELSS p58 A90-15430 Prediction of thermal stress casualtias vocalition in the cat p 34 A90-16284 [ADA2123561 p50 N90-13022 c.ntnl Inst forth. Deaf. s.lnt Lour YO. Mzoru Unlv., Tucson. Binaural masking: AD analysis of models Effectsof simulatedweightlessnand sympathectomy [ADA2115781 p48 N90-12168 I on madmum V02 of tn& rats p 32 A90-15491 Ch- Unhr., IL Army Aeronndlcal R.uuth Lab., Fort Ruckw,AL Pre-Motic organic matter from comets and asteroids IlllnolB lrut Of loch.. chlcrgo. Visual acuity and stereopsis with night vision goggles p64 A90-16160 Computer generation of a tutorial dialogue [ADA21 15521 p47 N80-12167 Clndnrutl Unlv., OH. [ADA2119761 p46 N90-12162 Army Natkk Remrch and De- Command. Genetic engineering of enhanced microbial nitrification Indla~Unlv.. Bloomlngton. MA. [P889-2083341 p36 N90-12155 The amphibian egg as a model system for annlyzing Air Force fliht feeding. Volume 1: Evaluation of current colondo State Unlv, Fort Collins. gravity effects p 28 A90-15074 system and alternative CMlCepts Phase separated membrane tioreactor - Results from Subcellular components of the amphibian egg - Insights [ADA2127691 p63 N90-13043 model system studies p 80 AW-15447 provided by gravitational shldies p 28 A90-15075

c-1 Inst. for Perception RVO-TNO CORPORA TE SOURCE

IMWute tOr PWWphl RVO-TNO, SOOOt.rb.rg Notlocul Aeronautla end Space Admlnletmtbn. Anm New Mexlco State Unhr., Lao Cwa (Netheflenda). Reseerch Center, Yoffett FIaM, CA. Sources and processing of CELSS wastes Prs and posmiht postural contrd of the Dt Spacelab Life sciences and space research XXlll(3): Natural and p 59 A90-15435 mission astronauts examined with a tilting room artiilecosystems; Proceedings of the Topical Meetings New York Unlv, New York. [ IZF-1988-251 p63 N90-13039 of the 27lh COSPAR Plenary Meeting, Espoo. Finland, Life sciences and space research XXlll(3): Natural and Spatial tests for aviators July 1829,1988 p 57 A90-15426 artificial ecosystems; Proceedingsof the Topical Meetings [ IZF-1988-151 p63 N90-13041 Carbon balance and produclivity of Lemna gibba, a of the 27th COSPAR Plenary Meeting. Espoo. Finland, A+Qli,cation of active noise reduction for hearing candiiate plant for CELSS p 58 A90-15430 July 18-29, 1988 p 57 A90-15426 protacton and speech intelliibili improvement Waste recycling issues in bioregenerative life support Transpiration during life cycle in controlled wheat [IZF-1968-21J p63 N90-13042 p59 A90-15434 growth p 58 A90-15432 Sources and processing of CELSS wastes The case for cellulose production on Mars p 59 A90-15435 [AAS PAPER 87-2321 p60 A90-16531 Subcritical and supercritical water oxidation of CELSS Visual motion perception J model wastes p59 A90-15436 [ADA2109941 p46 N90-12180 Effect of iodine disinfection products on higher plants Jet Propuldon Lab.. CaIHomlt Inat of Tech., p29 A90-15438 Three stages and two systems of visual processing puu(.ru. Productivity and fwd value of Amaranthus cruentus [AD-A2126701 p 53 N90-13032 Advances in space robotics under non-lethal salt p 30 A90-15440 Nllgota Unhr. (Japan). [IAF PAPER 89-0521 p55 A90-13279 stress The Life Sciences program at the NASA Ames Research Subcritical and supercritical water oxidation of CELSS Space robotics in the 'Ws p 57 A90-14998 Center - An overview p30 A90-15476 model wastes p59 A90-15436 Phase separated membrane bioreactor - Results from Decreased swelling pressure of rat nucleus pulposus North Carolina State Unhr., Raleigh. model system studies p 60 A90-15447 associated with simulated weightlessness Membrane fusion: The role of polyphosphatidylinositol The NASA SET1 sky survey: Recent developments p31 A90-15485 [AD-AZl 12891 p36 N90-12156 p84 N90-12804 Carotid baroreflex response following 30 days exposure Three dimensional object recognition employing Johna Hopkina Unhr., BeMmon, YD. lo simulated microgravity p 44 A90-15502 combined visual and tactile sensing Fatigue, pilot deviations and time of day Siinificance of light and social cues in the maintenance [PB89-219469] p52 N90-12176 [NASA-CR-185369] p62 N90-13035 of temporal organization in man p 45 A90-15512 The rodent research animal holding facility as a banier to environmental contamination P L [NASA-TM-102237] p35 N90-12151 Cardiovascular. renal, electrolyte, and hormonal Pennaytvanlt State Unlv., University Park. Labontoln de Paychologle Experimentale, (innoble changes in man during gravitational stress, Wrist orientation effect on grip strength and (France). weightlessness. and simulated weightlessness: Lower endurance Psychologicalmechanisms involved in the disorientation body positive presswe applii by the antigravity suit [PB89-200935] p61 N90-12179 of pilots due to fliht wndiins [NASA-TM-1022321 p49 N90-13013 Phytoresource Research, Inc., College Station, TX. [ETN-89-95014] p 63 N90-13040 Natio~lAeronautlea and Space Admlnlttratlon. John Thin film bioreactors in space p 27 A90-15068 Lockheed Engineering and Sclenwa Co., Houston, TX. F. Kennedy Spece Center, Cocoa Beech, FL Using computer graphics lo design Space Station Changes of muscle function and size with bedrest Freedom viewing p 43 A90-15501 R [IAF PAPER 89-0931 p56 A90-13306 Caroti baroreflex response following 30 days exposure LOckhHd Englnnring and Sclencea Co., Waahlngton, to simulated microgravity p44 A90-15502 Ro~archTrlangk Inst., Rowarch Trlangle Perk, NC. Dc. National Aemnautlcr and Space Administration. NASA spinoffs lo bioengineering and medicine Effects of body posture on the interpretation of Lyndon 6. Johnm Space Center, Hourton, TX. [IAF PAPER 898831 p40 A90-13673 biomedical data obtained from manned missions Human factors and productivity on Space Station Retlne Foundation, Boston, MA. [IAF PAPER 89-5961 p 39 A90-13628 Freedom Eye movements and spatial panem vision USSR Space Life Sciences Digesl, Issue 24 [IAF PAPER 89-0871 p55 A90-13301 [AD-A211650] p48 N90-12169 [NASA-CR-3922(28)-lSSUE-24] p 35 N90-12152 Using computer graphics to design Space Station USSR Space Life Sciences Diest. Issue 22 Freedom viewing [NASA-CR-3922(26)-lSSUE-22] p 35 N90-12153 [IAF PAPER 89-0931 p 58 A90-13306 S USSR Space Life Sciences Digest. Issue 23 [NASA-CR-3922(27)-lSSUE-23] p 36 N90-12154 Effects of body posture on the interpretation of San JOM State Unlv., CA. biomedical data obtained from manned missions Significance of liht and social cues in the maintenance [IAF PAPER 89-5961 p 39 A90-13628 of temporal organization in man p 45 A90-15512 M Biochemical correlates of neurosensory changes in Science Appllcatlona Intematlonal Corp., McLean, VA. weightlessness Calcium displacement caused by electromagnetic YCalll Unlv., Montreal (Owbee). [IAF PAPER 89-5981 p39 A90-13630 fields Otolih-spinal reflex testing on Spacelab-I and Dl Thin film bioreactors in space p 27 A90-15068 [ADA21 26901 p 50 N90-13023 p 43 Ago-15495 Effect of iodine disinfecbn products on higher plants S0uth.ut.m Center for Electrid Engineering Modkel Coli. of Vlrglnla. Rkhmond. p 29 A90-15438 Education, Inc., Saint Cloud, FL Carotid baroreflex response following 30 days exposure Space Station accommodationof liesciences in suppod Effects of lype of responding on memorylvisualsearch to simulated microgravity p44 A90-15502 of a manned Mars mission Responding just yes or just no can lead to inflexible Mkhlgen Unlv., Ann Arbor. [AAS PAPER 87-2331 p35 A90-16532 performance Time-frequency factors in auditory perception [AD-A212764] p 53 N90-13033 [ADA21 1491J p49 N90-13016 Space physiology and medicine (2nd ediin) p46 A90-16625 Stanford Unlv., CA. Carbon balance and producti of Lemna gibba. a National A.rwuutia and Spece Admlnlrtration. candidate plant for CELSS p 58 A90-15430 N Langley Research Center, H6mpton, VI. Growth rate study of canavalin single crystals Space Station accommodationof lie sciences in support p34 A90-16420 ktlorul Aud.my of SChCW - Notlocul R-mh of a manned Mars mission State Unhr. of New York, Buff610. Council, Wuhlngton, DC. [AAS PAPER 87-2331 p35 A90-16532 Cellular and molecular mechanisms of high pressure Sound Localiation by Human Observers symposium Netlonal lnat of Standards end Technology, inotropy in cardiac muscle proceedings Qolthenburg. YD. [AD-A21 16951 p48 N90-12170 [ADA2128771 p51 N90-13028 Synergisticeffects of nitrogendioxide and carbon dioxide ktlocul AWOMUUCY and Spew Admlnbtmtlon, following acute inhalation exposures in rats Waahlngton, DC. [PB69-214779] p35 N90-12150 T Long-term exposure to zerc-g and the gastro-intestinal Novat AerO#pace Mdkal Research Lab., PenMcOle, tract function FL TOS Technology, Inc.. Yoffett Field, CA. [IAF PAPER 89-5691 p37 A90-13610 A Scheiner-principle pocket optometer for Waste recycling issues in bioregenerative lie support Effects of body posture on the interpretation of self-evaluation and biofeedback accommodation training p 59 A90-15434 biomedical data obtained from manned missions [ADA213171] p51 N90-13027 Sources and processing of CELSS wastes [IAF PAPER 89-5961 p 39 A90-13628 Nova1 Health Rewerch Center, San DI.00, CA. p 59 A90-15435 me biological clock of Neurospora in a microgravity Demonstration of replicable dimensions of heanh Subcritical and supercritical water oxidation of CELSS environment p 29 A90-15082 behaviors model wastes p 59 A90-15436 Gravitational biology and the mammalian circadian [ADA2119201 p48 N90-12161 timing system p29 A90-15085 Transpiration during life cycle in controlled wheat N6val Wlul R..urch Irut. B.th..d., YD. U growth p58 A90-15432 Radio frequency (13.56 MHz) energy enhances The role of computerized modeling and simulation in rewarming from mild hypothermia Un~vemityof Southern 111ino16,Carbondale. [ADA2127031 p N90-13024 the develqmant of life support system technologies 50 The biological clock of Neurospora in a microgravity p59 A90-15439 Effects of serial wetdry-wet cold exposure: Thermal environment p 29 A90-15082 The case for cellulose production on Mars balance. physical activity, and cognitiveperformance WhState Unhr., Logan. [AAS PAPER 87-2321 p60 A90-16531 [ADA21 27041 p51 N90-13025 Current and potenW productivity of wheat for a Space physiology and dine(2nd ediin) Novel Penonnd Rneerch and Development antor, controlled environment life support system p46 A90-16625 sen M.go, CA. p 57 A90-15427 Aerospace dine and biology: A continuing The effect of incentives on the reliability and validity of Utah Unlv., Salt Lake Clty. bibliiraphy with indexes (supplement 329) cognitive speed tests Investigation of resonant ac& magnetic field effects [NASA-SP-7011(329)] p46 N90-12173 [ADA2113481 p62 N90-12181 [AD-A211612] D 37 N90-12159 ~~ ~~

CORIWRA TE SOURCE Yale Univ. v V.t.nru Admlnktratlon Hoopltel, S.n Frnnclwo, CA. Thin film bioreactora in space p 27 AW-15068 Vhglnh Unlv., Cherlottoevllk. Shape instabilities of platelike structures. 1: Experimental obsecvations in heavily cold worked in situ , composites [AD42122511 p50 N90-13021 W Waehlngton State Unlv., Pullnun. Changes of muscle function and size with bedrest p43 A90-15501 Waehlngton Unhr.. Soeltle. Metamgnition and retrieval from long-term memory at Mount Everest [ADA21 16291 p52 N90-12177 WI.con.ln Unlv., Wkon. Life sciences and space research XXlll(3): Natural and artificial ecosystems; Proceedings of the Topical Meetings of the 27th COSPAR Plenary Meeting, Espoo. Finland, July 18-29. 1988 p 57 Am-15426 Wrlght State Unlv., Dayton, OH. 8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine p34 AW-16286 Y Yak Unlv., New Hevm. CT. Fear-potentiatedstartle as a model system for analyzing learning and memory [ADA212131 I p 53 N90-13029

c-3 FOREIGN TECHNOLOGY INDEX

AEROSPACE MEDICINE AND BIOLOGY /A Confinuing Bibliography (Supplement 334) March 1990

Experimental research on the applicabilities of Chinese G medicine to space medicine [IAF PAPER 89-601 I p39 A90-13633 QERMANY.FEDERAL REPUBLIC OF Typical Foreign Technology CZECHOSLOVAKIA Modular ASR system testbed for development and Index Listing Effect of space flights and hypokinesia on plasma insulin implementation of automation and robotics elements within levels and insulin receptors in rat liver future orbital systems [IAF PAPER 89-5641 p23 A90-13807 [IAF PAPER 89-0361 P54 A90-13269 The next 40 years in space - Aspects of human factors Pilot perfmnce is imeased after alternating hypo- in space research and hypergravity states p45 A90-15511 COUNTRY OF [IAF PAPER 89091 ] p37 A90-13304 INTELLECTUAL Increasing the radioresistance of mice with ivastimul Studies on Habitation Module and interconnecting ~33A90-15838 elements for a Mure European space station [IAF PAPER 890921 p 55 A90-13305 Unilateral centrifugationof the otoliths as a new method NETHERLANDS D to determine bilateral asymmetries of the otolith apparatus The use of graphs in the ergonomic evaluation of tall in men pilots' sitting posture DENMARK [IAF PAPER 89-5661 p37 A90-13809 Hormonal and cardiovaacularchanges during lower body Hemodynamics during head dawn tilting and lower body negative and positive pressures negative pressure and pharmacological interventions for r [IAF PAPER 89-6001 p39 A90-13832 countermeasures Central venous pressure in humans during sholt periods [IAF PAPER 89-5971 p 39 A90-13629 of weightlessness p44 A90-15504 Flukl distribution pattern induced by intravenous fluid loading during HDT [IAF PAPER 89-5991 p39 A90-13831 F Response of unicellular organisms to the conditions in low earth wbit Listings in this index are arranged alphabetically FINLAND [IAF PAPER 89-6101 p24' A90-13638 by country of intellectual origin. The title of the Early development in the mouse -Would it be affected Gravitational biology within the German microgravity document is used to provide a brief description of by microgravity7 p28 A90-15077 program - Current status and further pursuits the subject matter. The page number and the ac- FRANCE [IAF PAPER 89-6121 p24 A90-13640 Simulation bv oersonal workstation for Man-Machine West Germany's first space robot p 57 A90-14999 cession number are included in each entry to assist Gravity and the membrane-solution interface - Interface design ' the user in locating the citation in the abstract sec- [IAF PAPER 89-0891 p55 A90-13302 Theoretical investigations p28 A90-15059 Potential sitesfor the perceptionof gravity in theacellular tion. If applicable, a report number is also included Biomediil payload of the French-Soviet long duration slime mold PhySaNm polycephalum p 28 A90-15062 an identifying the document. flight First conclusions as aid in - Influence of proprioceptive information on space [IAF PAPER 89-5831 p37 A90-13606 orientation on the ground and in orbital weightlessness Effect on the cardiac function of repeated LBNP during p 42 A90-15079 a one month head down tilt Light microscopic analysis of the gravireceptor in [IAF PAPER 89-5931 p38 Am-13625 Xenqus larvae developed in hypogravity Orthostaticintolerance post space flight ~A multifactorial p28 A90-15081 disorder? The expression of a circadian rhythm in two strains of A [IAF PAPER 89-5951 p39 A90-13627 Chlamydomonas reinhardii in space p 29 A90-15083 Behaviour of single-cell organisms exposed to 3.5 billion years ago: Lite on Mars? Hints, indications, AUSTRALIA hypergravity speculations p64 A90-16380 Experiment on 'Discwery' STS 514 Aggregation of - IlAF PAPER 89-6071 p23 A90-13635 Studies on prediiing the resynchronization of the red cells and thrombocytes in heart disease, Polarity of root statocytes in space and in simulated circadian system after transmedian flights hyperlipidaemia and other condiins p 42 A90-15060 microgravily [DFVLR-FB-89-101 p48 N90-12172 [IAF PAPER 89-6081 p 23 A90-13636 Biochemical and physiological changes in glider pilots 6 Importance of the lg controls in interpreting the resuns during multihour flights of en experiment on plant gravihoplMl (Siack, D1 [DLR-FB-89-29] p49 N90-13018 mission) BULQARIA Effects of a time zone shiiof nine hours on the circadian [IAF PAPER 894091 p 24 A90-13837 Psycho-physiological studiis during the flight of the rhythms in cockpit aircrew members on longhaul flights second Bulgarian cosmonaut Sw of activation of human peripheral Mood [DLR-FB-89-31] p49 N90-13019 [IAF PAPER 89-5881 p38 A90-13821 mononuclear cells after a space fliiht [IAF PAPER 89-611 I p24 A90-13639 Selective hypergravity stimulation: Its effects on the I C human balance and gaN fumtbns - A model to assess. in normal gravity conditions, some aapects of the INTERNATIONAL ORQANIUTION 1 CANADA perturbations induced on human by microgravity Life sciences and space research XXlIl(5). Gravitational Requirements and concepts for the Space Station condiins biology; Proceedings of the Topical Meeting and Remote Manipulator System [IAF PAPER ST-890161 p40 A90-13729 Workshops XVll and XVlll of the 27th COSPAR Plenary [IAF PAPER 89-0891 p 55 A90-13289 Effect of CO2 and 02on developmmt and fructification Meeting, Espoo, Finland, July 18-29, 1988 Head cooling is desirable bul not essential for preventing of wheat in closed systems p 57 A90-15428 p25 A90-15051 heat strain in pilots p57 AM-13737 The C23A - First slap to a monitor!q system of CELSS ISRAEL Gas bubble coalescence in reduced gravity condiins in flight p 59 A90-15437 Geotropic sensitivity of hornets p 27 A90-15072 p30 A90-15446 Normalition of bone cellular responses occurs Carbon balance and productivny of Lemna gibba. a Otolispinal reRex testing on Spacelab-1 and D-1 between 7 and 14 days of simulated weightlessness in candidate plant for CELSS p 58 A90-15430 p 43 A90-15495 rats p31 A90-15488 The effect of concurrent strength and endurance training Plasma ANF concentrationsduring head-dorm bed rest on electromechanical delay, maximum voluntary of various duration (from several han, to one month) - J contraction. and rate of force development Role of LBNP countermeasure p 44 A90-15503 [ADA2133161 p51 N90-13028 Hemodynamics of leg veins dufing a 30 days bed rest JAPAN CHINA, PEOPLE'S REPUBLIC OF - Effect of lower body negative pressure (LBNP) Telescience teslbed for physiological experiments Changes in circadian rhyihm of multiple hormones and p 45 A90-15508 [IAF PAPER 894341 p37 A90-13267 their relationship with individual susceptibility in simulated Slate of the art of humanhachine dialoa tool A new mewfor autonomous retrieval of a satellie weightlessness prototvpes using a visual sensor and a manipulator [IAF PAPER 89-5651 p 37 A90-13608 [TELECOM-PARIS89-H001] p 82 N90-13038 [IAF PAPER 89-041 ] p 54 A90-1327:! A report of ground results for brain function experiments Psychological mechanisms involvedin the disorientation Development of the 2nd generation space robot in in space of pilots due to fliht condiins NASDA [IAF PAPER 89-5901 p38 A90-13624 [ ETN-89-950141 p63 N90-13040 [IAF PAPER 89051 I p54 A90-1327H

D-1 LITHUANIA FOREIGN TECHNOLOGY INDEX

Design and evaluation of mawin-the-loop control system U of Japanese Experimental Module Remote Manipulator system U.S.S.R. [IAF PAPER 894901 p55 A90-13303 Rwpeas of studii in space phytobiolcgy The basic haallh me system for the crew lunar base [IAF PAPER 89-5781 p23 A90-13617 [IAF PAPER 89-5731 p38 A90-13612 Binocular depth perception and its hyperacuity in Oxygen separation system of residential space at the common and specially selected sub- lunar base [IAF PAPER 89-588 J p38 A90-13622 [IAF PAPER 89-5741 p56 A90-13613 Medical results of the Riht of the second prime crew Study on the nitmgen fixation system required for plant on the station Mir culture in a lunar base [IAF PAPER 89-5941 p 38 A90-13626 [IAF PAPER 89-5751 p56 A90-13614 Cell mechanisms of adaptation to main factors of space niiht A study on culturing modules for CELSS in lunar base [IAF PAPER 89-6061 p23 A90-13634 [IAF PAPER 89-5781 p56 A90-13615 The effect of occupational work load on the functional Appliition of tubular photo-bioreactor system to culture state of naval-aviation fliht personnel spirulina for gas exchange and food production in p41 A90-14425 CELSS Dependence of Me ampli of kinesthetic evoked [IAF PAPER 89-5771 p56 A90-13618 potentias on the velodty and acceleration of the motion A foodlnubient supply plan for lunar base CELSS of a monkey's hand p 24 A90-14448 [IAF PAPER 89-5791 I p56 A90-13618 Miirogravily and musculoskeletal system of mammals Plant cultural system incorporated into CELSS p25 A90-15052 [IAF PAPER 89-5801 p57 A90-13619 Plant cell in the process of the adaptation to simulated Dorsal liiht response and changes of its responses microgravity p25 A90-15054 under varying acceleration conditions Calcium gradient in plant cells with polatized growth in p28 A90-15080 simulated microgravity p 26 A90-15056 Subcritical and supercritical water oxidation of CELSS Biological effects of galactic radiation HZE particles in model wastes p 59 A90-15436 experiments on the orbital station Salyut 7 Design for a bioreactor with sunlight supply and p 26 A90-15057 operations systems for use in the space environment Effects of prolonged exposure of lettuce seeds to HZE p 59 A90-15444 particles on orbital stations p 26 A90-15058 Closed and continuous algae cultivation system for food Plant cell plasma membrane structure and properties production and gas exchange in CELSS under clinostatting p26 A90-15061 p60 A90-15445 Ultrastructural and growth indices of Chlorella culture Difference in cardiovascular responses to blood pooling in multicomponent aquatic systems under space flight panems between LBNP and head up tilting stimulated after conditions p27 A90-15063 supine cycling in women p45 A90-15509 Long clinoslation influence on the localization of free Increasing central blood volume with headdown tilting and weakly bound calcium in cell walls of Funaria would inhibit water intake during mild pedaling at 25 C hygrometrica moss protonema cells p 27 A90-15064 and 35 C room temperatures in woman Long-term expriments on man's stay in biological p45 A90-15510 life-support system p 58 A90-15433 Active vibration control for flexible space environment Changes in kidney response to ADH under hypogravily use manipulators p60 A90-16522 - Rat models and possible mechanisms p 30 A90-15482 The effect of microgravity on the reproductive function L of male rats p 31 A90-15488 Calcium homeostasis in prolonged hypokinesia LITHUANIA p43 A90-15492 Evaluation of experiments involving the study of plant Microgravity-inducedchanges in human bone strength orientation and growth under different gravitational p43 A90-15493 conditions p25 A90-15053 Studies of space adaptation syndrome in experiments Formation and growth of callus tissue of Arabidopsis on primates performed on board of Soviet biosatellite under changed gravity p 25 A90-15055 'Cosmos-1887' p32 A90-15494 Immunocompetent cells producing humoral mediators of bone tissue mineral metabolism during space flight M simulation p43 A90-15496 Cardiorespiratory responses to simulated MEXICO weightlessness in man p44 A90-15505 Occupational injuries suffered by niiht anendants while Prevention of radiation sickness, induced by low-level on board p41 A90-13746 ionuing radiation, by repeated inktions with increasing doses of chemical radioprotectors p 33 A90-15633 Radioprotective properties of a Co(lll) biocomplex N p33 AOO-15634 NETHERUNDS Radioprotective effects of ATP and ADP on Developmental biology in space - Why and how? membrane-bound enzymes p 33 A90-15635 p 27 A90-15070 Accumulation of the biolog~A effects of microwaves Fertilization of frog eggs on a sounding rocket in as displayed in the behavior. the physical efficiency, the space p28 A90-15076 body-mass increase, and the condition of cerebral Influence of gravitoinerlial force on vestibular nystagmus neurons p33 A90-15637 in man obsenred in a centrihrge p 42 A90-15078 Characteristics of the response of animals belonging Re- and postflight postural control of the Dl Spamlab to various typological groups to high-frequency and mission astronauts examined with a tilting room microwave electromagnetic radiation p 34 A90-15638 [IZF-t988-25] p63 N90-13039 Predicting the postradiative radiosensitivity of mammals Spatial tests for aviators and man according to the LD50 criterion after acute [IZF-t988-15] p63 N90-13041 external inadation p 34 A90-15639 Effect of ionizing radation the binding of muscimol Applition of active noise reduction for hearing on protection and speech intelligibility improvement by synaptic membranes of the rat brain [ IZF-1988-21] p63 N90-13042 p34 A90-15640 NORWAY Effect of ultrah&dose ionizing radiation on the content Reduced systolic blood pressure elevations during of calhecholamine mediators in verious regions of the rat maximum exercise at simulated altitudes brain p34 A90-15641 p40 A90-13738 Biophysical principles of the effects of cosmic rays and RhyUlmic biological systems under micrc-g conditions radiation from accelerators p34 A90-16047 Neurochemistry of hibernation in mammals p 29 A90-15084 p 34 A90-16057 UNITED KINGDOM S Roboks and teleoperation p60 A90-16352 Work on human adaptation to long-term space flight in SPAIN the UK Insects as test systems for assessing the potential role [AAS PAPER 87-2371 p 46 A90-16536 of microgravity in biological development and evolution p 27 A90-15071 SWEDEN Responses to changed perfusion pressure in working muscles. Factors to be considered in exercise testing in space flihts7 p42 A9015481

D-2 CONTRACT NUMBER INDEX

~ ~~ ~ ~ ~~~ ~~~ AEROSPACE MEDICINE AND BIOLOGY /A Continuing Bibliography (Supplement 334) March 1990

Typical Contract Number Index Listing A90-15489 A90-15085 A90-15401 A90-15082 N90-12174 NAS10-10265 ...... p 20 N90-10571 N90-12175 A90-15432 A90-16531 I /-I A90-15427 A90-16288 NCC2-491 ...... A90-16284 NUMBER NUMBER N90-13035 --- NIH-HL-36597 A90-15500 N90-12180 A90-15442 Listings in this index are arranged alphanumeri- N90-12176 N90-12180 cally by contract number. Under each contract N90-12174 number, the accession numbers denoting docu- N90-13023 ments that have been produced as a result of re- N90-12159 search done under the contract are arranged in N90-13030 N00014-87-GO342 ...... N90-13026 ascending order with the AlAA accession numbers N00014-87-6-0135 .. N90-12180 appearing first. The accession number denotes the N00014-87-K-0433 ... NW-12166 number by which the citation is identified in the N00014-66-K-0354 ... N90-12180 N00014-8SK-0550 ...... N90-12170 abstract section. Preceding the accession number N00014-89J-1952 ...... NQO-12162 is the page number on which the citation may be N61339-61C-0105 ...... A90-13735 found. N61339-86-DM)26 ...... A90-13735 N68001-87-GO079 ...... A90-15480 PHSOH-02178 N90-12179 N90-12159 AF PROJ. 2312 D 38 N90-12158 ...... P48 N90-12170 p 53 N90-13029 PW N90-13023 AF PROJ. 2313 p46 ...... N90-12160 P 62 N90-12180 p48 N90-12168 PS N90-13030 p 48 N90-12169 106-3001 ...... P 35 N90-12151 p52 N90-12177 P 49 N90-13013 D4g N90-13018 199-50-82-07-OZ ...... D 84 N90-12604 p 53 N90-13032 AF PROJ. 2729 ...... N90-13022 A90-15487 P 32 A90-15498 AF-AFOSR-OOgSBB ...... N90-12158 AF-AFOSR-0126-66 ...... N90-12189 AF-AFOSR-0140-88 ...... p 46 N90-12160 P 53 NQO-13032 P 49 N90-13016 AF-AFOSR-0Y26-68 ...... P 52 N90-12177 AF-AFOSR-0296-86 ,..._...... ,. , .. . Pa N90-12188 AF-AFOSR0336-67 ...... ____...... PM N90-13029 A85iK1077 ...... Pa N90-13041 A87iKi048 ...... Pa N90-13042 BMFl-Ol-QVBB075 ...... P 37 A90-13609 DA PROJ. 3E1-62767-A6-78 ...___._...... p 47 N90-12165 DAAE07gSCR076 ...... P 62 N90-13037 NW-13043 N90-12156 N90-12157 N90-13021 N90-12174 A90-1 5442 N90-13040 A90-1 5503 A90-15504 N90-12155 ...... N90-13033 N90-13022 A90-15074 A90-15075 A90-15082 A90-15085 A90-15499 AM-15082 AW-15082 A90-16420 N90-12178 N90-12152 P 35 N90-12153 PS N90-12154 NASW-4300 ...... p 51 A90-13308 NASW-4387 ...... p 40 A90-13673 NASW-4435 ...... p 62 N90-13036

E- 1 REPORT NUMBER INDEX

AEROSPACE MEDICINE AND BIOLOGY /A Continuing Bibliography (Supplement 334) March 1990

Typical Report Number Index Listing AFHRL-TP-89-46 ...... P54 N90-13034 # IAF PAPER 89-595 ...... P 39 A90-13627 # IAF PAPER 89-596 ...... p 39 A90-13628 * # AFHRL-TR-88-75 ...... p 53 N90-13033 # IAF PAPER 89-597 A90-13629 # A90-13630 * # N90-13031 # AFIT/CI/CIA-86-238 P 53 IAF PAPER 89-599 A90-13631 # NUMBER NUMBER IAF PAPER 89-600 A90-13632 # AFOEHL-89-023RCQlllDRA p 48 N90-12171 # ...... IAF PAPER 89-601 A90-13633 # IAF PAPER 89806 p A90-13634 # NASA-TM-102151 p 20 N90-10571 # N90-12180 # ...... 23 ...... IAF PAPER 89-607 p 23 A90-13635 # N90-13018 # ...... IAF PAPER 89-608 A90-13636 # i AFOSR-89-1113TR ...... P 52 N90-12177 # IAF PAPER 89-609 A90-13637 # AFOSR-89-1131TR N90-13032 # A90-13638 # N90-12158 # IAF PAPER 89610 ...... p 24 IAF PAPER 89611 A90-13839 # AFOSR-89-115lTR p 48 N90-12189 # ...... A90-13640 # AFOSR-89-1164TR ...... p 48 N90-12168 # IAF PAPER 89-683 ...... p 40 A90-13873 * # AFOSR-89-1221TR P 53 N90-13029 # ISSN-0171-1342 N90-12172 # Listings in this index are arranged alphanumeri- ARIEM-M8689 ...... p 47 N90-12185 # ...... ISSN-0171-1342 ...... p 49 N90-13018 # cally by report number. The page number indicates ISSN-0171-1342 N90-13019 # ARO-23767.7-LSF ...... p 36 N90-12156 # the page on which the citation is located. The ac- ISSN-0751-1381 N90-13038 # ARO-25177.4-MS-1 ...... p 50 N90-13021 # cession number denotes the number by which the ARO-25263.1-CH ...... p 36 N90-12157 # IZF-1988-15 ...... p 83 N90-13041 citation is identified. An asterisk (') indicates that IZF-1988-21 p 63 N90-13042 CCIEM-88-RR-33 ...... p 51 N90-13028 # ...... the item is a NASA report. A pound sign (#) indi- IZF.1988-25 ... P 83 N90-13039 cates that the item is available on microfiche. DNLR-FB-89-10 ..... p48 N90-12172 # NAMRL-1344 ...... p 51 N90-13027 # DLR-FB-89-29 P 49 N90-13018 # ...... NAS 1.15102232 p 49 N90-13013 A-89084 ...... p 49 N90-13013 * # DLR-FB-89-31 ...... p 49 N90-13019 # ...... t NAS 1,15102237 ...... p 35 N90-12151 ff A-89183 ...... p 35 N90-12151 * # N90-12173 EOTR88-10 ...... p 52 N90-12175 * # NAS 1.2&183151 ...... N90-13036 * ff EOTR-89-02 ...... p 52 N90-12174 # AAS PAPER 87-232 A90-16531 ' NAS 1.26185369 ...... p 82 N90-13035 # AAS PAPER 87-233 ...... A90-16532 * NAS 1.26:165517 N90-12174 * # EPA/600/D-89/080 N90-13015 # ...... N90-12175 * iY AAS PAPER 87-234 ...... A90-16533 EPA/600/M-89/011 ...... p 36 N90-12155 # NAS 1.26185518 AAS PAPER 67-235 ...... A90-16534 NAS 1.26185855 N90-12178 :# NAS 1.2&3922(28)-lSSUE-22 p 35 N90-12153 AAS PAPER 87-236 ...... A90-16535 ETN-89-94482 N90-13039 ...... NAS 1.263922(27)-ISSUE-23 p 36 N90-12154 * AAS PAPER 87-237 ...... p 46 A90-16536 ETN-89-95014 N90-13040 # ...... NAS 1.2&3922(28)-ISSUE-24 p 35 N90-12152 AAS PAPER 87-238 A90-16537 ETN-89-95090 ...... p 63 N90-13041 ...... A90-16538 ETN-89-95307 p 48 N90-12172 # ...... N90-13036 X AAS PAPER 87-240 ...... p 81 A90-16539 ETN-89-95505 p 82 N90-13038 # NASACR-183151 ...... N90-13035 * ff AAS PAPER 87-242 ...... P 61 A90-16541 N90-13018 # ETN-89-95838 P 49 N90-12174 # N90-13019 # ADA210994 p 48 N90-12180 # ETN-89-95840 P 49 NASA-CR-185518 N90-12175 * # ...... ETN-89-98005 ...... p 63 N90-13042 N90-12156 # NASA-CR-185655 N90-12178 * # NASA-CR-3922(26)-ISSUE-22 p 35 N90-12153 * ADA21 1294 N90-12168 # IAF PAPER ST-89-012 A90-13727 # ...... NASACR-3922(27)-lSSUE-23 ...... p N90-12154 N90-12157 # IAF PAPER ST-89-018 ...... A90-13729 # 38 N90-12181 # NASA-CR-3922(28)-lSSUE-24 ...... p 35 N90-12152 ADA211368 ...... p 38 N90-12158 # IAF PAPER 89-026 p 54 A90-13281 # ...... NASA-SP-701l(329) p 48 N90-12173 * ADA211491 ...... p 49 N90-13016 # IAF PAPER 89-034 A90-13287 # ...... AD-A211552 ...... P 47 N90-12167 # IAF PAPER 89-036 A90-13269 # ADA211578 ...... p 48 N90-12168 # IAF PAPER 89441 A90-13272 # NASA-TM-102232 ...... p 49 N90-13013 * # N90-12151 * # ADA211812 ...... p 37 N90-12159 # IAF PAPER 89-050 ...... p 54 A90-13277 # NASA-TM-102237 ...... p 35 ADA21 1629 ...... P 52 N90-12177 # IAF PAPER 69-051 A90-13278 ... # N90-13043 ADA21 1648 ...... p 62 N90-13037 # 4490-13279 * # NATlCK/TR-89/039-VOL-l P63 # ADA211850 ...... p 48 N90-12189 # IAF PAPER 69-069 ...... p 55 A90-13289 # NHRC88-41 N90-12161 # ADA211695 . N90-12170 # IAF PAPER 89-084 ...... p 55 A90-13300 # ...... P 46 N90-13017 # IAF PAPER 89-087 p 55 A90-13301 # ...... NISTIR-89/4105 ..__ N90-12150 # ADA211787 ...... p 48 N90-12171 # IAF PAPER 89-080 ...... p 55 A90-13302 # P 35 N90-12180 # IAF PAPER 89-090 A90-13303 # NMRl-89-35 N90-13025 ADA21 1920 ...... p 46 N90-12161 # IAF PAPER 89-091 A90-13304 # ...... P 51 # NMR1-89-48. N90-13024 # ADA211976 ...... p 46 N90-12182 # IAF PAPER 89-092 ...... p 55 A90-13305 # P 50 ADA212069 P 47 N90-12163 # IAF PAPER 89-093 A90-13306 # N90-12181 ADA212128 P 49 N90-13014 # IAF PAPER 89-098 A90-13308 * # NPRDCTR-89-14 ...... P 82 # ADA212131 P 53 N90-13029 # IAF PAPER 69-563 A90-13606 # NSF/ENG-88037 N90-12176 # ADA212156 ...... p 47 N90-12164 # IAF PAPER 69-564 ...... p 23 A90-13607 # P 52 ADA212170 ...... P 47 N90-12185 # IAF PAPER 89-565 P 37 A90-13808 # ...... N90-12179 ADA21 2242 ...... P50 N90-13020 # IAF PAPER A90-13609 # PB89-200935 P 61 # 89566 N90-12155 ADA212251 ...... P50 N90-13021 # A90-13610 # PB89-208334 P 36 # N90-12150 ADA212287 ...... p 53 N90-13030 # IAF PAPER 89-573 ...... A90-13612 # PB89-214779 ...... P 35 # ADA212358 ...... p 50 N90-13022 # IAF PAPER 89-574 A90-13613 # PB89-219489 ...... P 52 N90-12176 # ADA212528 PB89-223630 N90-13015 # N90-13031 # IAF PAPER 89-575 ...... p 56 A90-13814 # ...... P 49 ADA212670 N90-13032 # IAF PAPER 89-576 ...... p 56 A90-13615 # N90-13023 # A90-13618 # SAIc89/1587 ...... p 50 N90-13023 # N90-13024 # IAF PAPER 89-578 A90-13617 # SDEPL-002 p 53 N90-13030 # N90-13025 # IAF PAPER 89-579 ...... A90-13618 # ...... N90-13033 # IAF PAPER 89580 ...... A90-13819 # TD88-4123 p N90-13041 ADA21 2765 N90-13034 # A90-13620 # ...... 63 TD89-0321 ...... p63 N90-13042 N90-13043 # IAF PAPER 69-588 ...... p 38 A90-13621 # N90-13026 # TD89-0532 ...... p 63 N90-13039 IAF PAPER 89-588 p 38 A90-13822 # ADA213171 . N90-13027 # ...... ADA213318 ...... p 51 N90-13028 # IAF PAPER 89-590 ...... p 38 A90-13624 # TELECOM-PARlS89-li001 ...... p 82 N90-13038 # IAF PAPER 89-593 ...... p 38 A90-13625 # ADSTR-3213-01 ...... p62 N90-13037 # IAF PAPER 89-594 P 38 A90-13626 # UCI-51 ...... p82 N90-12180 # F-1 ~

USMRL-899 REPORT NUMBER INDEX

USMRLBB-9 ...... p47 NW-12167 # USAFOEHL-88-023RC0111DRA .. p 49 NW-13017 X USAFSAM-TR-88-23 ...... p50 NW-13022 X USARIEM-MIS49 ...... p47 NW-121&0 # USARIEM-M80g968 ...... p50 NW-13020 # USARIEM-M61-89 ...... p 49 N90-13014 # UTEC-89036 ...... p 37 N90-12159 #

I F-2 ACCESSION NUMBER INDEX

~~ March 1990 AEROSPACE MEDICINE AND BIOLOGY /A Continuing Bibliography (Supplement 334)

Typical Accession Number A90-15434 * p 59 N90-12152 * P 35 Index Listing A90-15435 * p59 N90-12153 p 35 A90-15436 p59 N90-12154 * P36 A90-15437 p59 N90-12155 # p36 A90-15438 * p 29 N90-12156 # P36 A90-15439 * p 59 N90-12157 # P36 N9O-iO;" j pf , A90-15440 p30 N90-12156 # P36 , N90-12159 P37 j # A90-15442 p 30 A90-15444 p59 N90-12160 # P46 A90-15445 p60 N90-12161 # p46 A90-15446 p 30 N90-12162 # P46 A~~~\~~NSPONSORED MICROFICHE NUMBER A90-15447 * p 60 N90-12163 # p47 r=-pqpqF A90-15477 p42 N90-12164 # p47 A90-15478 * p 30 N90-12165 # P47 A90-15479 p30 N90-12166 # P47 A90-15480 p42 N90-12167 # P47 A90-15481 p42 N90-12168 # P48 Listings in this index are arranged alphanumeri- A90-15462 p 30 N90-12169 # p48 cally by accession number. The page number listed A90-15483 p31 N90-12170 # p48 N90-12171 # p46 to the right indicates the page on which the citation A90-15464 p 31 A90-15465 p31 N90-12172 .# P 48 is located. An asterisk (*) indicates that the item A90-15486 p31 N90-12173 p48 is a NASA report. A pound sign (#) indicates that A90-15467 p31 N90-12174 '# p 52 the item is available on microfiche. A90-15488 031 NW-12175 # p 52 A90-15489 p 32 N90-12176 # P52 A90-15490 p43 N90-12177 # P52 A90-15491 p32 N90-12178 '# p 61 A90-15492 p 43 N90-12179 # p61 A90-13261 # P54 A90-13738 p40 A90-15493 p43 N90-12160 # P62 A90-13267 # P37 A90-13739 p 40 A90-15494 p32 N90-12161 # p62 N90-12804'# P64 A90-13269 # P54 A90-13740 p41 A90-15495 p43 A90-15496 p43 N90-13013 '# P 49 A90-13272 # P 54 A90-13741 p41 A90-15497 p32 N90-13014 # P49 A90-13277 # P54 A90-13742 p41 A90-13278 # P54 A90-15496 p 32 N90-13015 # P49 A90-13279 # P 55 A90-13743 p52 A90-15499 * p 32 N90-13016 # P49 A90-13289 # P 55 A90-13744 p41 A90-15500 p33 N90-13017 # p49 A90-13300 # P55 A90-13745 p 41 A90-15501 * p 43 N90-13018 # p49 A90-13301 '# P 55 A90-13746 p41 A90-15502 * p 44 N90-13019 # P49 A90-13302 # P55 A90-13747 p 52 A90-15503 p44 N90-13020 # P 50 A90-13303 # P55 A90-13903 p 24 A90-15504 p 44 N90-13021 # p50 A90-13304 # P37 A90-14425 p41 A90-15505 p44 N90-13022 # p50 A90-13305 # P55 A90-14446 p 24 A90-15506 p 44 N90-13023 # P 50 A90-13306 '# P 56 A90-14631 p24 A90-15507 p44 N90-13024 # P 50 A90-13308 '# P51 A90-14998 * # p 57 A90-15508 p45 N90-13025 # P51 A90-13606 X P37 A90-14999 # p 57 A90-15509 p45 N90-13026 # P51 A90-13807 # P23 A90-15051 D25 A90-15510 p45 N90-13027 # P 51 A90-13608 # P37 A90-15052 p 25 A90-15511 p45 N90-13026 # p51 A90-13609 # P37 A90-15053 P 25 A90-15512 * p 45 N90-13029 # P 53 A90-13610*# P37 A90-15054 P 25 A90-15633 p 33 N90-13030 # P 53 A90-13612 # P38 A90-15055 P 25 A90-15634 p33 N90-13031 # P53 A90-13613 # P56 A90-15056 P 26 A90-15635 p33 N90-13032 # P53 A90-13614 # P56 A90-15057 P 26 A90-15636 p 33 N90-13033 # p53 A90-13615 # P56 A90-15058 P 26 A90-15637 p33 N90-13034 # P 54 A90-13616 # P56 A90-15059 P26 A90-15638 p 34 N90-13035 * # P 62 A90-13617 # p23 A90-15060 P 42 A90-15639 p 34 N90-13036 # P 62 A90-13618 # P56 A90-15061 P26 A90-15640 p34 N90-13037 # P 62 A90-13619 # P57 A90-15062 P 26 A90-15641 p34 N90-13038 # P62 A90-13620 # P 57 A90-15063 P 27 A90-15800 p60 N90-13039 P 63 A90-13621 # P38 A90-15064 P 27 A90-18035 p63 N90-13040 # P 63 A90-13622 # P 38 A90-15068 * A90-16047 p34 N90-13041 P63 A90-13624 # P38 A90-15070 P 27 A90-16057 p34 N90-13042 P63 A90-13625 # P 38 A90-15071 P 27 A90-16160 * p64 N90-13043 # P63 A90-13626 # P38 A90-15072 P 2728 A90-16284 * p 34 1 A90-13627 # P 39 A90-15073 A90-16286 * p 34 A90-13626 '# P 39 A90-15074 P 28 A90-16299 p45 A90-13629 # P39 A90-15075 A90-16352 p60 A90-13630 '# P 39 A90-15078 P 28 A90-16360 p64 A90-13631 # P39 A90-15077 P 28 A90-16420 * p 34 A90-13632 # P39 A90-15078 P 42 A90-16522 p 60 A9013633 # P39 A90-15079 P 42 A90-16531 * p60 A90-13634 # P23 A90-15080 P 28 A90-16532 * p35 A90-13635 # P23 A90-15081 P 28 A90-16533 p60 A90-13636 # P23 A90-15082 P 29 A90-16534 p6l A90-13637 # P24 A90-15083 P 29 A80-16535 p46 A90-13638 # P24 A90-15084 P29 A90-16536 p46 A90-13639 # P24 A90-15085 P 29 A90-16537 p46 A90-13640 # P24 A90-15428 * P 57 A90-16538 p46 A90-13673 '# P 40 A90-15427 * P 57 A90-16539 p61 A90-15428 A90-13727 # P40 P 57 A90-16541 p6l A90-15429 P58 A90-16625 * p46 A90-13729 # P40 A90-15430 P% A90-13735 P40 A90-15431 P58 A90-13736 P40 A90-15432 * PS N90-12150 # p35 A90-13737 p57 A90-15433 P56 N90-12151 '# D 35 AVAILABILITY OF CITED PUBLICATIONS

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Schedule A STANDARD PRICE DOCUMENTS AND MICROFICHE

NORTH PRICE AMERICAN FOREIGN CODE PRICE PRICE A01 $ 8.00 $ 16.00 A02 11 .oo 22.00 A03 15.00 30.00 A04-AO5 17.00 34.00 A06-AO9 23.00 46.00 A1 O-A13 31 .OO 62.00 A14-Al7 39.00 78.00 A1 8-A21 45.00 90.00 A22-A25 53.00 106.00 A99 NO1 60.00 120.00 NO2 59.00 118.00 NO3 20.00 40.00

Schedule E EXCEPTION PRICE DOCUMENTS AND MICROFICHE

NORTH PRICE AMERICAN FOREIGN CODE PRICE PRICE E01 $10.00 $ 20.00 E02 12.00 24.00 c E03 14.00 28.00 E04 16.50 33.00 E05 18.50 37.00 E06 21.50 43.00 E07 24.00 48.00 E08 27.00 54.00 EO9 29.50 59.00 E10 32.50 65.00 El1 35.00 70.00 E12 38.50 77.00 E13 41 .OO 82.00 E14 45.00 90.00 El5 48.50 97.00 E16 53.00 106.00 El7 57.50 115.00 E18 62.00 124.00 E19 69.00 138.00 E20 80.00 160.00

E99 * + Contact NTlS for price quote.

IMPORTANT NOTICE NTIS Shipping and Handling Charges US., Canada, Mexico - ADD $3.00 per TOTAL ORDER All Other Countries - ADD $4.00 per TOTAL ORDER Exceptions - Does NOT apply to: ORDERS REQUESTING NTlS RUSH HANDLING ORDERS FOR SUBSCRIPTION OR STANDING ORDER PRODUCTS ONLY NOTE: Each additional delivery address on an order requires a separate shipping and handling charge. 1. Report No. 2. Government Accession No. 3. Recipientk Catalog No. NASA SP-7011(334) I 4. Title and Subtitle 5. Report Date Aerospace Medicine and Biology March 1990 A Continuing Bibliography (Supplement 334) 6. Performing Organization Code

7. Author@) 8. Performing Organization Report No.

10. Work Unit No. 9. Performing Organization Name and Address National Aeronautics and Space Administration 11. Contract or Grant No. Washington, DC 20546

13. Type of Report and Period Covered 12. Sponsoring Agency Name and Address

14. Sponsoring Agency Code

15. Supplementary Notes

16. Abstract This bibliography lists 254 reports, articles and other documents introduced into the NASA scientific and technical information system in February 1990.

18. Distribution Statement Unclassified - Unlimited

19. Security Classif. (of this report) 20. Security Classif. this page) 21. No. of Pages 22. Price * Unclassified Unclassified 94 A05lHC

*For sale by the National Technical Information Service, Springfield, Virginia 22161

NASA-Langley, 1990