______-__ - _ _-_ - _ _ _ _ _ - _
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a VOID SHEET
TO: License Fee Management Branch r
1 FROM: Rlli - _ James MullaueL \ ( SUBJECT: VOIDED APPLICATION
Control Number: 303322___
Applicant: Case Western Rese License Number: 34-00738-07_ Docket Number: 030-07040 {_ 1 Date Voided: 12/18/97 Reason for Void: The licensee's reauest does not require an amendment. A Dhb > > o a L2fl.? 99 ' ' ' / f Signa}ture ( Date Attachment: Official Record Copy of Voided Action l FOR LFMB USE ONLY b Refund Authorized and processed - / \ No Refund Due ; Fee Exempt or Fee Not Required g\g' Comments: Log completed Processed by: . 5 /rd /J k , [i 9712290059 97121s - PDR ADOCK 03007040 f ||;' | h gj C PM - ** * * - I - - _ _ - . - ...... ,. - 3 (FOR LFM5 USE) INFORMAT!DN FRp'. LTS O BETWEEN: ------i :- License Fee Management Branch, ARM Program Code: 03510 and Status Code: 0 ! --Q Regional Licensing 3ections Fee Cate r: EI 3E Esp. Dat 0011031 : Fee Comments: 170.11(A)(4) Decom Fin Assur Reqdt N O ::::::::::::::::::::::::::::::::::::: LICENSE FEE TRANSMITTAL O A. REC 10N 1. APPLICATION ATTACHED $ Q Applicant / Licensee CASE WESTERN RESERVE UNIVERSITY ' Received Date 971114 '1, Docket No 3007040 -- Control No.: 303322 a License No. 34-00738-07 :: Q Action Types (;m e= 1me nt 2. FEE ATTACHED Amounts Q ,, ,,,, G seck No.: ,,,, __,_, a c~ 3. COMMENTS j ' O si n,, , je- Da e [[[[[h , E f:7 [' '_'',, Q B. LICENSE FEE MANAGEMENT BRANCH (C esh, epsmiWiton is entered /_/),/ * 1. FeeCategoryandAmountsfh _ k L .. ,__,,______2. CorrectFeePaid./Applicationmaybeprocessedfor Q Amendment ,,,,,t,,,,,,,, _ Renewal ,_,,____,..,_,, License , , , , , , , . . . . , , O 3. OTHER ,_____,,,,___,,,______,,,_,,__,,,, ______.-.. ______O , oe ____ Sdined i::H2$b%::::::::::::::::>1 0 -L,,,___ggy,jg7g______nemma ______------O DEC 0.11997 ?..?f!!';p~~~~~~~~___~___- -__- rac*my__ 7_c- -- -" -~~~~~ O M"* - Datc Chod RW'4 -- -- Droe Com u -- - - -- ~~ ~~ O M K p W- - w l]7 t .i, . , s. , . < 1. . g CASEWESTERN RESERVE UNIVERSITY . November 12,1997- Materials Licensing Branch U.S. Nuclear Regulatory Commission Region Ill 801 Warrenville Road Lisle, Illinois 60532-4351 Re: Case Western Reserve Univers!: ' NRC License Nos. 34-00'138-04 34-00738-07 34-00738-09 34-00738-10 To whom it anay concern: 'lhis is a request that Dr. David S. McPhecters (curriculum vitae enclosed) be appointed Chairperson of the Case Western Reserve University (CWRU) Radiation Safety Committee. We request that Dr. McPhr Mers be appointed for a two year term, starting January 1,1998. I am enclosing a listing of the current CWRU Radiation Safety Committee members. Dr. Mcpheeters will be replacing Dr. Christopher Town as Chairpersen. A search for a replacement for Dr. Town on the Radiation Safety Committee is in progress. If you have any questions, please call me at 216-368-2906. Sinc,erely,' , A} * , ," /- J >4 , , n & W. David Sedwick Radiation Safety Officer RECEIVED W S/gcj w,Jp0;M/$jN)|IIf[C,$d[fNOV 141997 yp , REGION III Departme t of Occupational & Environmental Safety y ~ f# C se e Fieserve Umversity B g F rs Floor ax 3 2220 Circle Drive, First Floor .. Clevetand. Ohio 44106-7227 # 3 y ; .g ; ,, J ______ -, 6 , ' ' ' , , - , CI'RRICULUM VITAE DAVID S. MCPHEETERS DepartmentofBlochennstry - Case Western Reserve University Schoolof Medicine Cleveland, Ohio 44106 ' (216)-368-8816- email: [email protected] EDUCATION Ph.D., Molecular, Ceilular and Deselopmental Biology 1987. University of Colorado, Boulder. H.S., Biology : 1981 University of 'Vashington, Seattle. Drake Unive sity, Des Moines. 1977-1978 PROFESSIONAL POSITIONS Assistant Professor 1993-present Department of Biochemistry, Case Western Reserve University, Cleveland. r Senior Research Fellow with Dr. John Abelson 1992 1993 ISvision of Biology, California Institute of T:chnology, Pasadena. Scientist 11 and Project Leader, Molecular Genetics Group, 1990-1992 7eaGen Research Center, Fort Colhns. - Research Fellow with Dr John Abelson 1987-1990 Division of Biology, California Institute of Technology, Pasadena. Graduate Research Assistant with Dr. l arry Gold 1982-1987 Department of Molecular Cellular and Developmental Biology, University of Colorado, Boulder. A W A R DS + " Catalytic Roles of the Sman Nuclear RNAs in Splicing" 5/1/95-4/30/99 National Institutes of Ileaht;. IR0lGM52310, 3428,600 " Expression of the Yeast inosine Monophosphate Dehydrogenase Gene" 12/1/93-11/30/94 American Cancer Society, $15,000 NI!! Individual National Research Service Award 1988 1990 NIlI predoctoral traineeship 1981 1984 - - _ - ______, ______. - * . *| .: . .* DAVID S. MCPHEETERS .Page 2 PROFESSIONAI, SOCIETIES The RNA Society - American Associa0an far the Advancernent of Science PUHi,1 CATIONS : ; Muhlenkamp, P., McPhecters, D.S.1997. The PRP22 protein specifically recognizes the 3' splice site in yeast pre- mRNA introns, manuscript in preparation. Mcpheeters, D.S.1996 Interactions of the yeast U6 RNA vith the pre mRNA branen site. RNA 11. Ii101123. McPhecters, D.S; 1994. Rapid bacteriophage T4 mRNA preparations and the pr'n.cr. extension assay. In: The Molecular Biology of Bacteriophage T4, ed. Karam, J.D., Arnetican Society for Microbiology,469-472. McPhecters, D.S. and Abelson, J.1992.' Mutational analysis of the yeast U2 SNRNA suggests a structural similarity to the catalytic core of group i introns. Cell 71,819-831, 1 Ilartz, D., Mcpheeters, D.S., Green, L and Gold, L 1991. Detection of Esc /wrichia coli ribosome binding at translation inillation sites in the absence of '.RNA. hurnal of Molecular Biology 218,99-105. Ilartz, D., Mcpheeters, D.S. and Gold, L 1991. Influence of mRNA determinants on translation initiation in Escherichia coli. Journal of Molecular Biology 218,83 9.7, ' MeVnecters D.S.1991. l'NA footprinting. In: Methods in Nucleic Acids Research: Biochemical Aspects. eds. ' Warr, G.W., Chao, L and Karam, J.D., CRC Press, 252-268. Ilartz, D., Mcpheeters, D.S. and Gold, L 1990. Prom polynucleotide to natural mRNA translation initiation - the function cf Escherichia coli initiation factors. In: The Structure, Funct:on and Evolution of Ribosomes. cd. Ilill, W.IL, American Society for Microbiology, 275-280. Pabrizio, P., Mcpheeters, D.S. and Abelson, J.1989. L '.,ro assembly of yeast U6 SNRNP; A functional assay. Genes & Development 3,2137 2150. - Mcpheeters, D.S., Pabrizio, P. and Abelson, J.1989. In vitra reconstitution of functional yeast U2 snRNPs. Genes & Development 3,2124-2136. ' Ilartz, D., Mcpheeters, D.S. and Gold, L 1989. Se'ection of the initiator TRNA by Escherichia coli luitiation factors. Genes & Development 3,1899-1912. McPhecters, D.S., Stormo, G.D. and Gold, L 1988, The autogenous regulatory 1,ite on the bacteriophage T4 gene ' 32 messenger RNA. Joumal of Molecular Biology 201,517 535. Ilutz, D., Mcpheeters, D.S., Traut, R. and Gold, L 1988. Extension inhibition analysis of translation initiation ..cc,mplexes. Methods ia Enzymology 164,419-425. - Mcpheeters, D.S., Gosch, G. and Gold, L 1988. Nucleotide sequences of the bacteriophage T2 and bacteriophage T6 gene 32 messenger RNAs Nucleic Acids Research 16,9341. - Gauss, P., Krassa, K.B., Mcpheeters, D.S., Nelson, M.A. and Gold, L 1987. Zinc (II) and the single-stranded DNA . bincling protein of bacteriophage T4. Proceedings of the National Academy of Sciences, U.S.A. 84,8515-8519. : Mcpheeters, D.S., Christensen, A., Young, E.T., Stormo, G. and Gold, L 1986. Translational regulation of- - , expression of the bacteriophage T4 lysozyme gene. Nucleic Acids Research 14,5813-5826. - _ _ _ _ _ - ______- _ _ _ _ _ - _ _ _ _- _ _ _ _ _ . _ _ _ . _ _ . . . . _ . _ . _ _ . . _ _ _ , . . _ . _ _ . . _ _ . . - . _ -. _ _ _ ._ _.______. *- ,; ,' . y ! DAVID S. McFliF.INERS L - Page 3) I - - IIelfort,~ M., Pedersen-Lane, J., Ehrenman, K., Chu, F., Mrsley, O.P., Maley, F., McPheetert, D.S. and Gold, L. ~ . ' - 1986. RNA splicing and in vivo expresion of the intron containing td gene of bacteriophage T4. Gene 41,93-102. j EXPERIENCE WITH RADIOACTIVE MATERIALS .; = Graduate Research Assistant 1982 1987 Department of Molecular, Cellular and Develonmental Biology, University of Cokrado, Boulder ' i Performed experiments involving3 11, IdC ,35S , and 32P . Umited experience with 65Zn. Responsible for Inventory, RAM surveys, and training of new laboratory personnel. . 1987 1990 Research Fellow _ . Division of Biology, California Institute of Technology Performed experiments involving 14C ,35 S ,and32p, * Scientist !!, Molecular Genetics Group, 1 h 1992 ZeaGen Research Center, Ibrt Collins. . Performed experiments involving 35S and32p, Responsible for inventory and RAM surveys. Research Fellow. 1992-1993 Diviaton of Biology, Californ4 Institute of Technology Performed experiments involving 35S and32p, Assistant Professa and Authorized User 1993-present Department of Diochemistry, Case Western Reserve University Performed experiments involving 353 ,32 P, ar.d33p, Responsible for inventory, RAM surveys, and training of new laboratory personnel. 4 University Radiation Safety Conunitiec 1995-present Case Western Reserve University Responsible for external audits of the CWRU Radiation Safety Office, evaluation and approval of authorized-user status for new investigators and animal experimentation involving R/.M. REFERENCES John Abelson, Professor end Chairman ' Division of Biolncy Califomia Institute.of Technology Pasadena. California 91125 ; (818r356-3945 - Larry Cx.!d, Professor and Chairman , < Departrnent of Mo'ecular, Cellular and Developmental Biology Universtty of Coloracki Boulder, Colorado 80309 (303)-492-7864 Manuel Ares,Jr., Professor Diology Department Sinsheimer Laboratories ; University of Califcania Santa Cruz ~ Santa Cruz, Califamia 95064 - J - ;.- -- . ,. ,- . . - . ~ , , . - . . . - . - . - - . , .- _ - - - -- = ...... - - - - - . - -. .-- . . - . - . - . - . - - . . - - * - . . . . RADIATION SAFIm'COMMrITEE VOT1NG MEMBERS Dr. Heleri Evans Dr. David Mcpheeters Department of Radiology Department of Biology BRB #325 ' SOM W432 x1099 (Fax # 1142) x1612 (Fax # 4544) August 8,1998 August 8,1998 Dr. Jack Hertsold Dr.Jolm McGervey Department of Medicine Department of Physio BRB #309B Rockefeller # 124 x8758 (Fax # 1166) x3632 (Fax # 4761) August 3,2000 August 1,2000 Dr.Mucelo Jacobs-Ix>rena Dr. James Plantner Department of Genetics Department of Ophthalmology BRil # 631 Wearn # 643 x2791 (Fax #3432) 844-3612 (Ex # 844-5812) August 8,1999 August 1, l'98 Dr. Ilue-Lee Cheng Kaung - Dr.F lavid Sedwick, RSO Department of Fediatrics Depai enent of Occupational & Env. Safety BRB D32 Serv'.cc Building ist Floor x5272 (Fex # 844-3757) x2'>06 (Fax # 2236) August 30,1997 Dr. Thomas II. Large Dr. Chistopher Town Department of Neurosciences Department of Biology SOM # 611 Millis Science Center # 114N x4954 (Fax # 46S0) x3593 (Fax #4672) . August 8,1999 January 1,1998-Chair EX-OFFICIO MEMBERS Kenneth Basch Richard Dell Treasurer's Ikpartment Safety Services Adelbert Hall #302 Service Building,1st Floor x4394 (Fax # 8690) x2907 (Fax # 2236) ! VISITING MEMBER Dr. P.S. Rao Radiology Department Wearn Btalding, Room B21 844 5922 ..- - , . - . . - _ -. _ _ . _ _ - . .__ _.__ __ ._. _ _ . _ . _ _ _ _ _ . . _ ' ,[ , 4, - DATE: |***|,Y~7T , CORRESPONDENCE CLARIFICATION-SHEET , - a REVIEWER: =BJ H0i.T- UU2iEE LICENSEE: _ bv A)42/# w LICENSENUMBERi 38-Jb733- [ OT L/F /0 The following correspondence has been received from the above licensee and it is not clear what action (O is(are) required: Please review this corres)ondence and indicate which of the following applies, and please return to Deb)ie Hersey, as soon as possible. . Additional-Information to Control No.- . - Process in as a new action, additional information, and no fee required. ; - Process as new licensing action. Review has already been started on Control No. _ and this information cannot be ' combined with current-in house action. - Can be combined with Control No. . Review has not started. ___ Appears to be information for the license file file it. -- Licensee is adding Nucl dr Pharmacists. - Amendment is necessary . Amendment is not necessary . (Information for license file) - Licensee is adding authorized users. -- A check is included . - No check is-included . Amendment-is neces ary . Amendment is not necessary . , (This is a Notification) ' Process'in as a new licensing action: ' \ ~ ~ Amendme B. enewai- C. - New License Application Other: - Thank You For Your Help!!! 10/16/96 ' , _ _ - _ _ - _ _ _ - - e,- * t . f * "4 . UNITED STATES p - 9[%, _ NUCLEAR RE ULATORY COMMISSION (q % REGION til U ij 801 WARRENVILLE ROAD USLE. ILUNOIS 60532-4351 - *** November 21. 1997 _ . W. David Sedwick. Ph.D. Radiation Safety Officer- Case Western Reserve University Dept. of Occupational and Environmental Safety 10900 Quail Buil.ing Cleveland. OH 44106 SUBJECT: ACKNOWLEDGEMENT OF CORRESPONDENCE (Letter Dated November 12. 1997) Dear Licensee: In response to your re' ast, we have completed the initial processing, which is -an administrative revis,< of your application for a(n): __ New License X Amendment ,_ Renewal __ Termination _ Auth User (Ameridment not required) ,_ Other No administrative deficiencies were identified during this initial review. However, it should be noted that a technical reHew may identify omissions in the stibmitted information. It appears that your request is routine (see 1-3 below, as applicable). 1. New and amendment actions are normally processed within 90 days, unless we find major deficiencies, or policy issues requiring central program office assistance. n 2. Renewal actions are normally processed within 180 days however, under timely filing (before expiration), you may continue to operate under your existing license. 3. Termination actions are normally processed within 90 days, unless confirmatory surveys following decontamination / decommissioning activities are involvad. A copy of your corresaondence has been forwarded to our Licensing Fee and Debt Collection Branc1 (301/415-6097) for approval of the fee category and amount, if required. ET If you have a compelling safety or business-related reason for requesting expedited review. please contact the Materials Licensing Branch at (630) 829-9887. We will try to complete your request as soon as practicable. Any correspondence about this request should reference the control number. Nuclear Materials Support Branch Mail Cor. trol No. 303322 License No. 34-00738-07 ______