Curriculum Vitae
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1 CURRICULUM VITAE David Ross Engelke EDUCATION 1974 University of Wisconsin, Madison, B.S. (Biochemistry) 1979 Washington University, St. Louis, Ph.D. (Biological Chemistry) Advisor: Robert G. Roeder POSTDOCTORAL TRAINING 1979-1983 Postdoctoral Fellow, Department of Chemistry, University of California, San Diego, La Jolla, California, Advisor: John Abelson ACADEMIC APPOINTMENTS 1983-1989 Assistant Professor, Department of Biological Chemistry, The University of Michigan, Ann Arbor, Michigan 1989-1996 Associate Professor, Department of Biological Chemistry, The University of Michigan 1996-2015 Professor, Department of Biological Chemistry, University of Michigan 1995 Interim Director, Medical Scientist Training Program 1995-1998 Director, Cellular and Molecular Biology Ph.D. Program, The University of Michigan 1998-2007 Founding Director, Program in Biomedical Sciences, The University of Michigan 2000-2007 Assistant Dean, Graduate and Postdoctoral Studies, UM Medical School 2008-2012 Associate Dean, H. H. Rackham School of Graduate Studies University of Michigan 2009-2010 Founding Director, Michigan Postbaccalaureate Research Education Program (PREP) 2010-2015 Associate Director, Michigan PREP 2013-2015 Chair, Department of Biological Chemistry, University of Michigan 2015-present Professor of Chemistry, University of Colorado Denver | Anschutz Professor of Biochemistry and Molecular Genetics, UC Denver | Anschutz Dean of the Graduate School, UC Denver | Anschutz CONSULTING POSITIONS 1989-1994 Parke-Davis 1990/91 Merck Inc. 1994 NeXstar, Inc. 2000 Parke-Davis 2001 Pfizer 2002 PTC Therapeutics, Incyte, Imgenix, Ambion 2003 Promega, Nucleonics, Pfizer 2004 Benitec, Promega 2004-2005 Benitec Science Advisory Board 2007 Somalogic, Inc. 2010 Allozyne, Inc. 2 SCIENTIFIC ACTIVITIES 1. Grant + Program Review Service Ad hoc reviewer, National Science Foundation 1984-present Member, NIH Molecular Cytology Study Section 1991-95 Representative, NIH Director’s Chairpersons Meeting 1992 Ad hoc member, ACS review panel 1995, 1996 Ad hoc for NIH site visits (2) Member, NIH Biology 2 Study Section 1997-1998 Chair, NIH CDF6 Study Section 1999-2001 Ad hoc for NCI intramural site visit 2002 Ad hoc for NIH CDF2 Study Section 2002 Reviewer, Norwegian Research Council 2003-2010 Reviewer, U. of Miami Biochemistry Dept. Review 2007 Reviewer, U. of Illinois, Chicago, Graduate Programs 2008 Reviewer, U. of Oklahoma Cell Biology Program 2009 Reviewer, Ohio State U. College of Biological Sciences 2009 Ad hoc for NIGMS Genetics ARRA applications 2009 Reviewer, UCLA Biochemistry Dept. and Program 2010 Ad hoc for NIGMS MGB Study Section 2010 Member, NIGMS Special Emphasis study sections (2) 2014 2. Journal Review Associate Editor, RNA (1999-2009) Editorial Board, Nucleic Acids Research (1990-2015) Frequent reviewer for: Biochemistry EMBO J. J. Mol. Biol. Mol. Cell. Biol. J. Biol. Chem. Nucleic Acids Res. Proc. Natl. Acad. Sci. RNA Science Genes & Development Nature Cell Nature Biotech. Molecular Cell Nature Structural and Molecular Biology RECENT EXTRAMURAL INVITED PRESENTATIONS (2002- PRESENT) 2/02 Seminar, Sherbrooke University (Quebec) 3/02 Seminars, Case Western Reserve University (Cleveland) 5/02 Session organizer, International RNA Society Meeting (Madison) 5/02 PTC Therapeutics seminar (New Jersey) 6/02 Incyte Genomics seminar (Newark, Delaware) 6/02 Speaker and session organizer, RNA Polymerases I/III meeting (Asilomar) 8/02 Ambion Inc. seminar (Austin, TX) 10/02 Seminar, University of Notre Dame (South Bend) 11/02 Speaker, “RNA in Drug Development” meeting (San Diego) 12/02 Seminar, City of Hope National Medical Center (Los Angeles) 1/03 Seminar, Nucleonics (Malvern, PA) 1/03 Seminar, Geisinger Clinic (Danville, PA) 1/03 Seminar, Penn State U. Medical School (Hersehy, PA) 2/03 Speaker, “Applications of RNA Interference” conference (San Diego) 2/03 Invited course lecture, Imgenex (San Diego) 3 2/03 Seminar. Stratagene (San Diego) 2/03 Seminar, Michigan State University (East Lansing) 3/03 Speaker and session chair, Gene Functional Analysis Conference (Santa Clara, CA) 4/03 Seminar, U. of South Carolina (Columbia) 6/03 Seminar, Promega (Madison) 6/03 Seminar, Pfizer (Ann Arbor) 9/03 Seminar, Carnegie Mellon University 9/03 Speaker, American Chemical Society meeting, New York 10/03 Speaker, International tRNA Symposium, Banz, Germany 1/04 Seminar, NIH campus 3/04 Seminar, University of Saint Francis 4/04 Seminar, University of Rochester 5/04 Speaker, Benitec session at RNAi meeting, Boston 6/04 Speaker, RNA Polymerase I + III Conference, Asilomar (sent student substitute) 9/04 Speaker, Sherbrooke (Canada) RNA meeting 9/04 Seminar, University of Toledo 10/04 Seminar, Indiana University 11/04 Seminar, Brown University 2/05 Seminar, Ohio State University 4/05 Seminar, Colorado State University (Fort Collins) 5/05 Seminar, U. of Massachusetts (Amherst) 5/05 Seminar, U. of Colorado (Boulder) 8/05 Seminar, Sigma-Aldrich (St. Louis) 10/05 Seminar, Oberlin College 01/06 Seminar, U. of Georgia 05/06 Seminar, U. of Missouri 05/06 Speaker, RNA Polymerase I+III meeting, Asilomar, CA 10/06 Seminar, U. of Arizona 11/06 Seminar, U. of Colorado Health Sciences Center 11/06 Seminar, Michigan State University 5/07 Speaker, Cancer Research UK, London 11/07 Speaker, Michigan Society of Fellows 6/08 Speaker, CIRTL meeting Madison, WI 6/08 Speaker, OddPols meeting, Quebec City, Canada 9/08 Seminar, U. of Oklahoma 9/08 Invited Speaker, Midwest Yeast Meeting, Northwestern U. 10/08 Seminar, Penn State U. 6/09 Speaker, RNA Society meeting, Madison 9/09 Presenter, Nuclear Structure and Dynamics meeting, France 1/10 Seminar, University of Southern California 2/10 Seminar, University of Missouri 6/10 Speaker, RNA Polymerases I + III meeting, Airlie Center, Virginia 7/10 Session chair, World Conference on Research Integrity, Singapore 10/10 Session chair, GREAT group, New Orleans (Program Committee) 11/10 Keynote speaker, MCB Symposium, U. of Iowa 8/11 Seminar, University of Alberta 5/12 Seminar, Stowers Institute (Kansas City) 6/12 Speaker, Session Chair, RNA Pol I+III meeting, Airlie Center, VA 5/13 Speaker, EMBL, Heidelberg 4 10/13 Seminar, National Institutes of Health, Bethesda 6/14 Speaker, Symposium for Anita Hopper 6/14 Organizer, speaker, RNA polymerases I, III, IV + V meeting, Ann Arbor 9/14 Speaker/Session Chair, International tRNA Conference, Kyllini, Greece 5/15 Organizer, Future of Bioscience Graduate and Postdoctoral Training Conference, Ann Arbor, MI 3/16 Speaker, Colorado RNA Club, Boulder 5/16 Organizer, speaker, RNA polymerases I, III, IV + V meeting, Ann Arbor 9/16 Speaker, RiboClub, Sherbrooke, Canada GRANT SUPPORT Ongoing support R25 GM086262-06 (PI: Barald, Engelke is co-I) 12/01/08-09/01/15 0.0 calendar NIH/NIGMS $1,488,602 total costs Michigan Postbaccalaureate Research Education Program This training grant provides up to 10 underrepresented minority recent bachelor’s degree graduates with the opportunity of a 1 year research and preparation for graduate school in the biosciences. Engelke was originally the PI at the time of award, but changed to co-Investigator (and Associate Director) after becoming Associate Dean of the central graduate school in 2009. the first year with permission of NIGMS. OVERLAP: none DGE-1553798 (PI: Engelke) 09/15/15-08/31/20 0.0 calendar NSF $184,000 total costs Graduate Research Fellowship Program The purpose of this grant is to help ensure the vitality and diversity of the scientific and engineering workforce of the United States. The program recognizes and supports outstanding graduate students who are pursuing research-based master’s and doctoral degrees in science and engineering. The GRFP provides three years of support for the graduate education of individuals who have demonstrated their potential for significant achievements in science and engineering. This appointment of Dr. Engelke as the new Dean of the UC Denver/Anschutz Graduate School is pending approval of NSF. OVERLAP: none Completed Support RO1 GM082875-01A1 D. Engelke (PI) 07/01/08-04/30/12 Agency: NIGMS “Nuclear Organization of RNA Polymerase III Transcription” PI: D. Engelke, 25% effort The goal of this proposal is to understand the spatial organization of RNA polymerase III transcription units in eukaryotes and the mechanisms by which these genes are organized. Cayman Chemical contract (Engelke) 05/20/13-05/19/14 Cayman Chemical Company This contract was to create nucleic acid aptamers that recognize specific histone modifications. R25 GM086262 (PI: K. Barald, co-I D. Engelke) 12/01/08-11/30/17 0.0 calendar NIH/NIGMS $341,310 annual direct costs Michigan Postbaccalaureate Research Education Program This training grant provides up to 10 underrepresented minority recent bachelor’s degree graduates with the opportunity of 1 year research and preparation for graduate school in the biosciences. Engelke was originally PI, but stepped down to be co-investigator in 2009 and resigned in 2015 to accept the position in Colorado 5 HRD 1038099 (PI: J. Weiss; co-I D. Engelke) 06/01/11-5/30/16 0.0 calendar National Science Foundation $1,250,000 total costs Building Bridges, Creating Community and Wise Mentoring: Building Institutional Capacity to Enhance Diversity in STEM Disciplines This is an institutional grant to coordinate campus-wide activities in promoting the diversity in the STEM disciplines and optimizing the success of young scientists. I resigned in 2014 since I had changed administrative positions at the University of Michigan HONORS AND AWARDS 1979-1980