Journal of Cancer 2020, Vol. 11 3559 Ivyspring International Publisher Journal of Cancer 2020; 11(12): 3559-3566. doi: 10.7150/jca.40154 Research Paper Optimal timing of antiviral therapy for patients with malignant tumor who presented with hepatitis B reactivation during chemotherapy and/or immunosuppressive therapy Xiaofang Zou1*, Longhua Guo1, Yinfang Gu1, Zhijun Yang1, Ping Huang1, Tianhuang Liu3, Jingjing Zhao4,5, Guowu Wu1,2* 1. Department of Medical Oncology, Cancer Center, Meizhou People’s Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, China 2. Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, China 3. Department of Hepatopathy, Meizhou People’s Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, China 4. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China 5. Department of Biotherapy, Sun Yat-sen University Cancer Center, Guangzhou, China *These authors contributed equally to this work Corresponding authors: Guowu Wu, MD; Department of Medical Oncology, Cancer Center, Meizhou People’s Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, No 63 Huangtang Road, Meijiang District, Meizhou 514031, P. R. China. Tel.: +86-753-2131682, Fax: +86-753-2204840, Email:
[email protected] Or Jingjing Zhao, PhD, MD; State Key Laboratory of Oncology in South China; Department of Biotherapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, P.