An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001815255-HmpCyc: Bacteroides sp. HMSC073E02 Cellular Overview Connections between pathways are omitted for legibility.

uracil an oligopeptide

RS25545 RS10320 RS04245 RS20080 RS11600 RS12675 RS12705 RS19870 RS18935 RS19850 RS19835 RS19825 RS08205 RS15745 RS14145 RS12040 RS10930 RS17675 RS06870 RS05990 RS21850 RS21855 RS22030 RS05995 RS17680 RS21860 RS21865 RS21870 RS12050 RS21875 RS07925 RS15270 RS19855 RS16540 RS05205 RS14425 RS02800 RS23580 RS05435 RS22630 RS23700

uracil an oligopeptide

RS02355

Carbohydrate Degradation Amine and Polyamine Degradation UDP-N-acetyl-α-D-muramoyl- 2-methoxy-6-all a plant DNA combined a [lipoyl-carrier (3R,5S)-3- D-alanyl-D-alanine 2-amino-6-[1-hydroxyethyl]- a nucleoside a ribonucleoside a ribonucleoside carbamoyl [2Fe-2S] iron-sulfur cluster biosynthesis Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis γ a ribonucleic acid formate asp trans-nonaprenyl- protein]-N 6 -[(R) hydroxy-1- superpathway of menaquinol-8 biosynthesis I flavin biosynthesis I (bacteria and plants) superpathway of demethylmenaquinol-8 biosynthesis I Secondary Metabolite Biosynthesis Aminoacyl-tRNA Charging Glycolysis glycolysis I (from glucose 6-phosphate) D-galactose degradation I (Leloir pathway) N-acetylglucosamine L-alanyl- -D-glutamyl-L-lysine 7-methyl-7,8-dihydropterin triphosphate triphosphate diphosphate arabinogalactan with exogenous superpathway of tetrahydrofolate biosynthesis heparin degradation 2-amino-4-hydroxy-6- phosphate 1,4-benzoquinol RS02395 degradation I bifunctional UDP- DNA-directed anaerobic ribonucleoside- ribonucleoside- aspartate bifunctional type I arabinogalactan endo- DNA to form a -dihydrolipoyl]- pyrroline-5- D-glucopyranose β N-acetylmuramoyl- hydroxymethyldihydropteridine RNA polymerase: triphosphate reductase: diphosphate reductase, carbamoyltransferase: demethylmenaquinone recombinational L-lysine dihydrolipoyl carboxylatepyrroline-5- L-cysteine desulfurase preQ biosynthesis tRNA charging -D-galactose N-acetyl-D- 1,4-beta-galactosidase: crossover junction chorismate chorismate 0 6-phosphate heparin tripeptide:D-alanyl- pyrophosphokinase: HMPREF3015_RS05470 adenosylcobalamin- HMPREF3015_RS18195 junction dehydrogenase: carboxylate reductase: GTP GTP myo-inositol biosynthesis glucosamine HMPREF3015_RS19365 methyltransferase/2- HMPREF3015_RS19155 endodeoxyribonuclease galactose-1-epimerase: heparinase: HMPREF3015_RS18040 HMPREF3015_RS09835 HMPREF3015_RS01060 superpathway of pyridoxal 5'-phosphate biosynthesis and salvage D-alanine ligase/ HMPREF3015_RS19370 anaerobic ribonucleoside- dependent: aspartate methoxy-6-polyprenyl- arabinogalactan endo- RuvC: cysteine desulfurase: isochorismate synthase: isochorismate synthase: glucose-6-phosphate HMPREF3015_RS09610 6-phosphateN-acetylglucosamine-6- RS07570 D-glucopyranose arg HMPREF3015_RS02290 alanine racemase: 2-amino-4-hydroxy-6- DNA-directed RNA triphosphate reductase: HMPREF3015_RS16310 carbamoyltransferase 1,4-benzoquinol HMPREF3015_RS00400 dihydrolipoyl pyrroline-5- HMPREF3015_RS07755 HMPREF3015_RS00970 bifunctional 3,4- HMPREF3015_RS00970 GTP isomerase: phosphate deacetylase: 1,4-beta-galactosidase: GTP cyclohydrolase I FolE: D-erythrose 6-phosphate arginine--tRNA ligase: [+ 2 isozymes] [+ 5 isozymes] HMPREF3015_RS14685 hydroxymethyldihydropteridine HMPREF3015_RS20595 regulatory subunit: methylase UbiE: dehydrogenase: carboxylate reductase: dihydroxy-2-butanone- HMPREF3015_RS16410 4-deoxy-2-O-sulfo- HMPREF3015_RS25490 polymerase subunit alpha: ribonucleotide-diphosphate HMPREF3015_RS15960 Holliday junction HMPREF3015_RS11655 4-phosphate GTP cyclohydrolase I FolE: HMPREF3015_RS15300 an L-arginyl- diphosphokinase: a 2'-deoxyribonucleoside a [lipoyl-carrier HMPREF3015_RS04785 an S-sulfanyl-[L- isochorismate isochorismate α-D-galactose β-L-erythro-hex-4- UDP-N-acetylmuramoyl- HMPREF3015_RS19530 reductase subunit alpha: HMPREF3015_RS18200 6-methoxy-3-methyl-2-HMPREF3015_RS04060 a galactotetraose resolvase RuvX: HMPREF3015_RS05830 4-phosphate synthase/ Arg D-glucosamine[+ 2 isozymes] 5'-triphosphate resolution of 6 7,8- 7,8- HMPREF3015_RS11655 [tRNA ] tripeptide--D-alanyl- HMPREF3015_RS05730 HMPREF3015_RS08805 N-carbamoyl- protein]-N - Hyp cysteine desulfurase] GTP cyclohydrolase II: Arg enopyranuronosyl-(1,4)-D-N [1-(2-amino-7-methyl-4-oxo- a ribonucleic acid a 2'- all-trans-nonaprenyl- recombinationalHMPREF3015_RS21235 2-succinyl-5-enolpyruvyl-6- dihydroneopterin dihydroneopterin Ins(3)P a tRNA F6P 6-phosphate L-aspartate lipoyl-L-lysine RS17360 HMPREF3015_RS09100 2-succinyl-5-enolpyruvyl-6- galactokinase: -sulfoglucosamine 6-O-sulfate D- alanine ligase: 7,8-dihydro-3H-pteridin- deoxyribonucleoside 1,4-benzoquinol junction hydroxy-3- cyclohexene-1- 3'-triphosphate hydroxy-3- cyclohexene-1- 3'-triphosphate 4-phospho- HMPREF3015_RS20965 α HMPREF3015_RS03560 6-yl)]ethyl diphosphate 5'-diphosphate formation of two carboxylic-acid synthase: 2,5-diamino-6-(5-phospho-D- 6-carboxytetrahydropterin inositol monophosphatase: fructose-bisphosphatase 6-phosphofructokinase: UDP-N-acetyl- -D-muramoyl-L-alanyl- carboxylic-acid synthase: D-erythronate intact strands ribosylamino)pyrimidin-4(3H)-one synthase: HMPREF3015_RS09505 α-D-galactose γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine an S-sulfanyl-[cysteine HMPREF3015_RS00975 HMPREF3015_RS00975 4-phosphoerythronate class III: HMPREF3015_RS17195 UDP-α-D-glucose α-D-glucosamine HMPREF3015_RS12150 4-deoxy-β-L-erythro-hex-4- desulfurase]-[disordered- [+ 2 isozymes] bifunctional [+ 2 isozymes] HMPREF3015_RS22635 [+ 2 isozymes] 1-phosphate 6-phosphate 7,8- dehydrogenase PdxB: myo-inositol cys enopyranuronosyl-(1,4)-D-N RS17380 form scaffold 2-succinyl-5- diaminohydroxyphosphoribosylaminopyrimidine 2-succinyl-5- 6-carboxy-5,6,7,8- cysteine--tRNA ligase: an inactive (R)-4'- all trans-decaprenyl- 2-methoxy-6-all 6-O-trans- a [2-oxoglutarate dihydroneopterin HMPREF3015_RS17220 -sulfoglucosamine 6-O-sulfate glucosamine-6- 3-methyl-2- deaminase/5-amino-6-(5-phosphoribosylamino) tetrahydropterin β-D-fructose 1,6- pyruvate phosphopantothenoyl- 2-methoxy-6- trans-hexaprenyl- DMK-12 DMKH protein] complex enolpyruvoyl-6- 3'-phosphate enolpyruvoyl-6- HMPREF3015_RS16795 an L-cysteinyl- β phosphate deaminase: ribonucleoside a reduced oxobutanoate hypoxanthine PRPP methoxy-mycolyl- dehydrogenase 2 (3R)-3-hydroxy-2-oxo- bisphosphate 4-deoxy- -L-erythro-hex- SAM 6 hydroxy-3-cyclohexene- uracil reductase RibD: HMPREF3015_RS07465 hydroxy-3-cyclohexene- 7-carboxy-7- Cys triphosphate flavodoxin phosphoenolpyruvate 3-methyl-2-oxobutanoate L-cysteine 1,4-benzoquinol 1,4-benzoquinol trehalose 6- E2 protein] N bifunctional bifunctional 4 phosphooxybutanoate [tRNA ] DHAP 4-enopyranuronosyl-(1,4) HMPREF3015_RS09905 bifunctional hypoxanthine bifunctional bifunctional 1-carboxylate 5-amino-6-(5-phospho- 1-carboxylate deazaguanine synthase: a tRNA Cys reductase anaerobic ribonucleoside- synthase/pyruvate dehydrogenase phosphate bifunctional alpha,alpha- -dihydrolipoyl- demethylmenaquinone demethylmenaquinone fructose-bisphosphate -D-N-sulfoglucosamine [+ 2 isozymes] phosphopantothenoylcysteine phosphoribosyltransferase: demethylmenaquinone demethylmenaquinone dihydrolipoyl 3-phosphoserine/ HMPREF3015_RS12155 triphosphate reductase phosphate dikinase: subunit VorB: trehalose-phosphate L-lysine methyltransferase/2- methyltransferase/2- RS02225 a [cysteine desulfurase]- D-ribosylamino)uracil aldolase: 6-O-sulfate hydrolase: decarboxylase/ methyltransferase/2- methyltransferase/2- 7,8- phosphohydroxythreonine activating protein: HMPREF3015_RS07015 HMPREF3015_RS11925 dehydrogenase: S-sulfanyl-[disordered- bifunctional 7-carboxy-7- triose-phosphate HMPREF3015_RS18455 F6P HMPREF3015_RS09760 phosphopantothenate-- methoxy-6-polyprenyl- methoxy-6-polyprenyl- synthase (UDP-forming)/ methoxy-6-polyprenyl- methoxy-6-polyprenyl- dihydroneopterin transaminase: D-glyceraldehyde HMPREF3015_RS11355 HMPREF3015_RS05465 xanthine HMPREF3015_RS05830 form scaffold (1R,6R)-6-hydroxy-2- diaminohydroxyphosphoribosylaminopyrimidine pyruvate deazaguanine isomerase: pyruvate, 2-oxoisovalerate 1,4-benzoquinol 1,4-benzoquinol trehalose-phosphatase: 1,4-benzoquinol 1,4-benzoquinol (1R,6R)-6-hydroxy-2- HMPREF3015_RS23595 3-phosphate [+ 2 isozymes] cysteine ligase CoaBC: phosphoribosyltransferase: dihydrolipoyl protein] complex succinylcyclohexa-2,4- dihydroneopterin aldolase: deaminase/5-amino-6-(5-phosphoribosylamino) glutamine--tRNA HMPREF3015_RS11645 N,6-O-disulfo-D-glucosamine anaerobic ribonucleoside- phosphate dikinase: dehydrogenase: HMPREF3015_RS20390 methylase UbiE: methylase UbiE: trehalose- HMPREF3015_RS09045 methylase UbiE: methylase UbiE: succinylcyclohexa-2,4- 1-deoxy-D-xylulose-5- 7-cyano-7-deazaguanine HMPREF3015_RS21275 dehydrogenase: diene-1-carboxylate HMPREF3015_RS16295 uracil reductase RibD: HMPREF3015_RS07465 4-phosphooxy- ligase/YqeY domain triphosphate reductase HMPREF3015_RS25370 HMPREF3015_RS09820 HMPREF3015_RS04060 HMPREF3015_RS04060 trans-methoxy- a [2-oxoglutarate HMPREF3015_RS04060 HMPREF3015_RS04060 RS09725 cysteine desulfurase: D-ribulose 5-phosphate diene-1-carboxylate synthase QueC: gln 4'-phosphopantetheine 6-methoxy-3-methyl- 6-methoxy-3-methyl-2- HMPREF3015_RS09835 L-threonine phosphate synthase: fusion protein: activating protein: IMP mono-mycolate dehydrogenase HMPREF3015_RS07755 o-succinylbenzoate 6-(hydroxymethyl) 5-amino-6-(5-phospho- o-succinylbenzoate HMPREF3015_RS14150 D-glyceraldehyde Alcohol Degradation phosphoenol NADH CO isobutanoyl-CoA 2-all-trans-decaprenyl- all-trans-hexaprenyl- menaquinol-12 MQH F0F1 ATP HMPREF3015_RS14675 an active diphosphate AMP H + 2 6 2 H + H + synthase: bifunctional 3,4- synthase: 4-hydroxythreonine- HMPREF3015_RS09370 an L-glutaminyl- HMPREF3015_RS20600 E2 protein] N synthase an S-sulfanyl-[cysteine -7,8-dihydropterin chorismate D-ribitylamino)uracil 3-phosphate a flavodoxin ribonucleoside pyruvate 1,4-benzoquinol 1,4-benzoquinol 1-deoxy-D-xylulose-5- preQ Gln dihydroxy-2-butanone- 4-phosphate 0 met 5'-deoxyadenosine -lipoyl-L-lysine HMPREF3015_RS00985 5-amino-6-(5-phospho- HMPREF3015_RS00985 [tRNA ] desulfurase]-S- 2-amino-4-hydroxy-6- phosphate synthase: Gln N-sulfo-D-glucosamine glycerophosphodiester semiquinone triphosphate aminodeoxychorismate 4-phosphate synthase/ dehydrogenase PdxA: a tRNA glyceraldehyde-3- RS02260 sulfanyl-[disordered- 2-succinylbenzoate hydroxymethyldihydropteridine D-ribitylamino) 2-succinylbenzoate HMPREF3015_RS20640 degradation reductase synthase component I: GTP cyclohydrolase II: HMPREF3015_RS10870 phosphate dehydrogenase: V-type ATP form scaffold pyrophosphokinase: uracil phosphatase: + + HMPREF3015_RS09100 3-amino-1- 1-deoxy-D- HMPREF3015_RS04200 H H O-succinylbenzoic HMPREF3015_RS05695 HMPREF3015_RS24755 O-succinylbenzoic a glycerophosphodiester synthase protein] complex HMPREF3015_RS18040 hydroxyacetone xylulose 5- a (2R)-2-hydroxy a 2-methyl a 3-O-acetylated a (3R)-3- 2-methoxy-6-all a 2-methoxy-6-all- 6-O-trans-keto- a [pyruvate a [protein]- acid--CoA ligase: 4-amino-4- 1-deoxy-L-glycero- acid--CoA ligase: glycerophosphodiester 2-amino-4-hydroxy-6- 1-phosphate phosphate O-acetyl-L-serine hydrogen selenide even numbered branched 2,3,4- rhamnogalacturonan I hydroxyhexacosanoyl- trans-octaprenyl- trans-polyprenyl- mycolyl-trehalose dehydrogenase DMKH2-13 L-tyrosine HMPREF3015_RS00990 deoxychorismate tetrulose 4-phosphate ARP HMPREF3015_RS00990 13-DPG D-glucosamine phosphodiesterase: hydroxymethyldihydropteridine glu straight chain 2,3,4- saturated fatty acid rhamnogalacturonan [acp] 1,4-benzoquinol 1,4-benzoquinol 6-phosphate E2 protein] N 6 bifunctional phosphate RS09720 UDP-glucose 4- O-acetylhomoserine long-chain fatty bifunctional bifunctional bifunctional alpha,alpha- protein-tyrosine- H + RS11595 H + 4-(2'-carboxyphenyl) 4-amino-4- 4-(2'-carboxyphenyl) pyridoxine 5'- pyridoxine HMPREF3015_RS02505 long-chain fatty acetylesterase: bifunctional UDP-3-O- a [cysteine diphosphokinase: pyridoxamine epimerase GalE: aminocarboxypropyltransferase/ saturated fatty acid acid--CoA ligase: demethylmenaquinone demethylmenaquinone trehalose-phosphate -dihydrolipoyl- demethylmenaquinone -4-oxobutyryl-CoA deoxychorismate lyase: 6,7-dimethyl-8- -4-oxobutyryl-CoA an L-glutamyl- [+ 4 isozymes] acid--CoA ligase: HMPREF3015_RS04390 [3-hydroxymyristoyl] dihydrolipoyl phosphatase: desulfurase]-(S- HMPREF3015_RS05730 phosphate synthase: sn-glycerol cysteine synthase: HMPREF3015_RS21750 synthase (UDP-forming)/ L-lysine methyltransferase/2- HMPREF3015_RS05690 Glu phosphoglycerate kinase: HMPREF3015_RS21845 N-acetylglucosamine methyltransferase/2- methyltransferase/2- dehydrogenase: HMPREF3015_RS00265 sulfanyl) -[disordered- 1,4-dihydroxy-2- (7,8-dihydropterin- ribityllumazine synthase: 1,4-dihydroxy-2- HMPREF3015_RS11590 pyridoxamine kinase: [tRNA ] HMPREF3015_RS21750 rhamnogalacturonan methoxy-6-polyprenyl- 2 glu 3-phosphate HMPREF3015_RS15515 methoxy-6-polyprenyl- methoxy-6-polyprenyl- trehalose-phosphatase: HMPREF3015_RS00485 UDP-glucose 4-epimerase: a (R)-2-hydroxy even [+ 3 isozymes]a 2-methyl deacetylase/3-hydroxyacyl- HMPREF3015_RS05830 protein tyrosine + + form scaffold naphthoyl-CoA synthase: 6-yl)methyl HMPREF3015_RS04150 naphthoyl-CoA synthase: HMPREF3015_RS12175 a tRNA L-rhamnose degradation I [+ 3 isozymes] acetylesterase: 1,4-benzoquinol H RS05210 H 4-aminobenzoate HMPREF3015_RS20430 O-acetylhomoserine numbered straight branched ACP dehydratase: 1,4-benzoquinol 1,4-benzoquinol trehalose- HMPREF3015_RS09045 phosphatase: RS20715 protein] complex HMPREF3015_RS00980 diphosphate HMPREF3015_RS00980 diphosphate AMP AMP diphosphate HMPREF3015_RS03740 dihydrolipoyl methylase UbiE: (2E,6E)-farnesyl (2E,6E)-farnesyl pyridoxine pyridoxamine α-D-glucopyranose α aminocarboxypropyltransferase/ HMPREF3015_RS04005 methylase UbiE: methylase UbiE: trans-keto- HMPREF3015_RS10090 IPP IPP 3-phospho- UDP-α-D-galactose -L- chain 2,3,4-saturated 2,3,4-saturated a rhamnogalacturonan dehydrogenase: HMPREF3015_RS04060 diphosphate 1,4-dihydroxy-2- 6,7-dimethyl-8-(1-D-ribityl)lumazine diphosphate 1,4-dihydroxy-2- acetate a (2E)-hexacos- HMPREF3015_RS04060 HMPREF3015_RS04060 mono-mycolate a [pyruvate a [protein]- 5'-phosphate 5'-phosphate D-glycerate 1-phosphate rhamnopyranose cysteine synthase: fatty acyl CoA fatty acyl-CoA type I 6-methoxy-3-methyl- a 6-methoxy-3-methyl- HMPREF3015_RS09835 naphthoyl-CoA naphthoyl-CoA L-rhamnose mutarotase: 2-enoyl-[acp] dehydrogenase L-tyrosine + + DHAP HMPREF3015_RS05310 2-all-trans-octaprenyl- 2-all-trans-polyprenyl- menaquinol-13 H RS22070 H riboflavin synthase: HMPREF3015_RS17375 E2 protein] N 6 a [cysteine desulfurase]- pyridoxamine 5'- pyridoxamine 5'- ile 2,3- 1,4-benzoquinol 1,4-benzoquinol 7,8- HMPREF3015_RS09400 isoleucine--tRNA ligase: [+ 2 isozymes] acetate L-selenocysteine -lipoyl-L-lysine [scaffold protein- phosphate oxidase: phosphate oxidase: cofactor-independent diphosphoglycerate- β-L- dihydropteroate HMPREF3015_RS17460 an L-isoleucyl- D-glucopyranose chitin degradation III (Serratia) (2Fe-2S)] complex all-trans-octaprenyl 2-carboxy-1,4- all-trans-octaprenyl HMPREF3015_RS14065 HMPREF3015_RS14065 phosphoglycerate mutase: dependent rhamnopyranose thr thr riboflavin 2-carboxy-1,4- Ile RS24770 diphosphate bifunctional diphosphate pyridoxal [tRNA ] HMPREF3015_RS15480 6-phosphate serine serine naphthoquinol naphthoquinol pyridoxamine 5'- pyridoxamine 5'- a tRNA Ile phosphoglycerate L-rhamnose isomerase: folylpolyglutamate synthase/ adenosylcobinamide-GDP chitin an odd numbered a 3-methyl- a 2-O-acetylated a (3R)-3- a [protein]- 2-methoxy-6-all 6-O-cis-methoxy- 5-dehydro- D-ribose 5- bifunctional riboflavin phosphate oxidase: phosphate oxidase: 2,3-bisphosphoglycerate- mutase: gpmA HMPREF3015_RS01095 a purine FAD oxaloacetate dihydrofolate synthase: salvage from cobinamide I straight chain branched 2,3,4- rhamnogalacturonan I hydroxytetracosanoyl- L-threonine trans-heptaprenyl- mycolyl-trehalose 4-deoxy-D- phosphate 1,4-dihydroxy-2-naphthoate kinase/FAD synthetase: 1,4-dihydroxy-2-naphthoate independent ribonucleoside adenosylcobinamide a [co-chaperone]- HMPREF3015_RS09320 HMPREF3015_RS20545 HMPREF3015_RS20545 2,3- 2,3,4-saturated saturated fatty acid rhamnogalacturonan [acp] FAD:protein FMN 1,4-benzoquinol 6-phosphate glucuronate oxaloacetate ribose 5-phosphate polyprenyltransferase: HMPREF3015_RS05035 polyprenyltransferase: keto-L-rhamnulose long-chain fatty bifunctional UDP-3-O- bifunctional bifunctional alpha,alpha- 5-dehydro-4-deoxy-D- thr thr [scaffold protein- cob(II)inamide phosphoglycerate mutase: diphosphoglycerate- 5'-triphosphate bifunctional fatty acid long-chain fatty acetylesterase: transferase: decarboxylase: isomerase B: RS24775 HMPREF3015_RS05380 7,8-dihydrofolate HMPREF3015_RS05380 superpathway of thiamine diphosphate biosynthesis I acid--CoA ligase: [3-hydroxymyristoyl] demethylmenaquinone trehalose-phosphate glucuronate isomerase: serine serine (2Fe-2S)] complex ATP:cob(I)alamin HMPREF3015_RS07800 dependent adenosylcobinamide acid--CoA ligase: HMPREF3015_RS04390 HMPREF3015_RS12700 HMPREF3015_RS14420 HMPREF3015_RS09655 monoglutamate FMN PLP [(1->4)-β-N-acetyl-D- HMPREF3015_RS21750 N-acetylglucosamine methyltransferase/2- synthase (UDP-forming)/ HMPREF3015_RS01630 SSQ1 chaperone: adenosyltransferase: leu phosphoglycerate kinase/adenosylcobinamide- HMPREF3015_RS21750 rhamnogalacturonan FAD:protein FMN oxaloacetate ribose 5-phosphate leucine--tRNA ligase: glucosaminyl] -(1->4)-2- an odd numbered [+ 3 isozymes]a 3-methyl- deacetylase/3-hydroxyacyl- methoxy-6-polyprenyl- trehalose-phosphatase: 5-dehydro-4-deoxy-D- HMPREF3015_RS18845 demethylmenaquinol-8 [corrinoid HMPREF3015_RS03040 bifunctional riboflavin demethylmenaquinol-8 mutase: gpmA n phosphate [+ 3 isozymes] acetylesterase: transferase: decarboxylase: isomerase A: cys HMPREF3015_RS10600 an L-leucyl- (acetylamino)-2-deoxy- L-rhamnulofuranose straight chain branched ACP dehydratase: 1,4-benzoquinol trehalose- HMPREF3015_RS09045 glucuronate isomerase: adenosyltranferase]- kinase/FAD synthetase: chitin guanylyltransferase: diphosphate AMP diphosphate AMP HMPREF3015_RS03740 a [chaperone-ATP]- Leu D-glucono-1,5-lactone HMPREF3015_RS04005 HMPREF3015_RS03165 methylase UbiE: HMPREF3015_RS08990 HMPREF3015_RS07090 RS09415 bifunctional HMPREF3015_RS05035 [tRNA ] 2-phospho- 2,3,4-saturated 2,3,4-saturated cis-methoxy- 3-deoxy-D-HMPREF3015_RS14710 D-ribulose [co-chaperone]- cob(II)inamide Leu rhamnulokinase: HMPREF3015_RS16580 a rhamnogalacturonan a 7,8-dihydrofolate cysteine desulfurase: a tRNA a purine adenosyl- fatty acyl CoA fatty acyl-CoA acetate a (2E)-tetracos- a [protein]-FMN- 6-methoxy-3-methyl-2-HMPREF3015_RS04060 mono-mycolate glycero-2,5- pyruvate [scaffold protein- demethylmenaquinone D-glycerate HMPREF3015_RS01090 type I AMP 5-phosphate FAD HMPREF3015_RS07755 chitinase: ribonucleoside cobinamide 2-enoyl-[acp] L-threonine all-trans-heptaprenyl- hexodiulosonate (2Fe-2S)] complex methyltransferase/2- dihydrofolate reductase: thiamine salvage II an [L-cysteine HMPREF3015_RS25665 rhamnulokinase: 5'-diphosphate phosphate 1,4-benzoquinol methoxy-6-polyprenyl- HMPREF3015_RS19690 a ThiS sulfur- phosphopyruvate [(1->4)-β-N-acetyl-D- [corrinoid desulfurase]-S- HMPREF3015_RS06065 SSQ1 chaperone ATPase: 1,4-benzoquinol carrier protein hydratase: glucosaminyl] -(1->4) [+ 3 isozymes] adenosyltranferase]- 4-amino-2-methyl-5- n L-rhamnulose methylase UbiE: sulfanyl-L-cysteine HMPREF3015_RS12740 a chitodextrin -N-acetyl-2-deoxy- RS25540 HMPREF3015_RS18845 cob(I)inamide pyrimidinemethanol val 1-phosphate undecaprenyl- a (3R)-3- 6-methoxy-2-all- 6-O-cis-keto- a (9Z)-3-oxo- 6-O-α-mycolyl- HMPREF3015_RS04060 a tetrahydrofolate cysteine desulfurase: valine--tRNA ligase: 2-amino-D-gluconate 18-hydroxystearate phytenate oleate adenosylcobinamide ATP:cob(I)alamin bifunctional D-glyceraldehyde phosphoenol diphospho-N- hydroxydocosanoyl- trans-octaprenyl- mycolyl-trehalose octadec-9- trehalose 6- a [chaperone- HMPREF3015_RS07755 HMPREF3015_RS11030 an L-valyl- rhamnulose-1- AMP an [2Fe-2S] adenosyltransferase: hydroxymethylpyrimidine 3-phosphate pyruvate chitinase: acetylmuramoyl- UDP-N-acetyl- long-chain fatty long-chain-fatty- long-chain fatty bifunctional [acp] 1,4-benzoquinone 6-phosphate enoyl-[acp] phosphate ADP]-[disordered- menaquinol-8 AIR a [ThiI sulfur- a carboxy- [tRNA Val ] phosphate aldolase: bifunctional UDP-3-O- bifunctional bifunctional alpha,alpha- 3-oxoacyl-ACP bifunctional alpha,alpha- cluster protein HMPREF3015_RS03040 kinase/ 1-deoxy-D-xylulose-5- HMPREF3015_RS25665 L-alanyl-γ-D- α-D-glucosamine acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: adenosylcobinamide form scaffold carrier protein]-S- adenylated-[ThiS a tRNA Val HMPREF3015_RS01105 [3-hydroxymyristoyl] demethylmenaquinone trehalose-phosphate reductase FabG: trehalose-phosphate 5'-nucleotidase: phosphomethylpyrimidine phosphate synthase: phosphoenolpyruvate glutamyl-L-lysyl- undecaprenyldiphospho- HMPREF3015_RS21750 HMPREF3015_RS16270 HMPREF3015_RS21750 kinase/adenosylcobinamide- protein] complex adenosylcobinamide phosphomethylpyrimidine tyr sulfanyl-L-cysteine N-acetylglucosamine methyltransferase/2- synthase (UDP-forming)/ synthase (UDP-forming)/ HMPREF3015_RS14675 sulfur-carrier protein] synthase/pyruvate pyruvate kinase: N,N'-diacetylchitobiose (S)-lactaldehyde DHAP D-alanyl-D-alanine muramoylpentapeptide beta-N- [+ 3 isozymes] [+ 3 isozymes] [+ 3 isozymes] phosphate HMPREF3015_RS11825 HMPREF3015_RS04825 kinase: synthase ThiC: ditrans,octacis- deacetylase/3-hydroxyacyl- methoxy-6-polyprenyl- trehalose-phosphatase: a (3R,9Z)-3- trehalose-phosphatase: RS22060 non-chaperonin molecular phosphate dikinase: HMPREF3015_RS15150 acetylglucosaminyltransferase: guanylyltransferase: chaperone ATPase: bifunctional HMPREF3015_RS05515 HMPREF3015_RS25400 1-deoxy-D-xylulose-5- 2-iminoacetate beta-hexosaminidase: undecaprenyldiphospho- 18-hydroxystearoyl- ACP dehydratase: 1,4-benzoquinol HMPREF3015_RS09045 hydroxy-octadec- HMPREF3015_RS09045 HMPREF3015_RS07015 pectin degradation II HMPREF3015_RS07940 AMP diphosphate diphosphate AMP phytenoyl-CoA diphosphate AMP oleoyl-CoA HMPREF3015_RS16580 trehalose-cis-keto- α, α'-trehalose adenosine HMPREF3015_RS18845 adenosylcobinamide phosphate synthase: synthase ThiH: HMPREF3015_RS18525 N-acetyl-(N-acetyl-β-D- CoA HMPREF3015_RS04005 methylase UbiE: 9-enoyl-[acp] 10 HMP-P HMP-P UDP adenosyl-cobinamide a (2E)-docos- mono-mycolate 6-α-mycolate a [disordered- N -formyl-tetrahydrofolate biosynthesis kinase/adenosylcobinamide- HMPREF3015_RS20640 HMPREF3015_RS25395 ala glucosaminyl)muramoyl- 3-methyl-6-methoxy-HMPREF3015_RS04060 an [Fe-S cluster thiamine diphosphate alanine--tRNA ligase: a methyl-esterified [+ 6 isozymes] phosphate phosphate 1-deoxy-D-xylulose a thiocarboxy- pyruvate γ 2-enoyl-[acp] biosynthesis form [Fe-S] cluster bifunctional bifunctional biosynthesis III HMPREF3015_RS01455 homogalacturonan chitin degradation II (Vibrio) L-alanyl- -D-glutamyl-L- 2-octaprenyl-1,4- guanylyltransferase: 2-iminoacetate [ThiS-Protein] an L-alanyl- N-acetyl-D-glucosamine chaperone]-ATP scaffold protein] a tetrahydrofolate hydroxymethylpyrimidine 5-(2-hydroxyethyl) hydroxymethylpyrimidine 5-phosphate (Staphylococcus) lysyl-D-alanyl-D-alanine benzoquinone RS07165 HMPREF3015_RS16580 [tRNA Ala ] kinase/ -4-methylthiazole kinase/ a tRNA Ala chitin thiazole synthase: HMP-PP a homogalacturonan adenosyl-cobinamide phosphomethylpyrimidine phosphomethylpyrimidine a nascent peptidoglycan a glycopeptide- β a (3R)-3- a (3R,11Z)-3- a (7Z)-3- HMPREF3015_RS25405 thiamine phosphate (15Z)- -D-fructofuranose methionine synthase: phosphate kinase: kinase: chitinase: γ linoleate 4 (S)-NADHX dihydrofolate reductase: synthase: glycolysis III (from glucose) Electron Transfer with (L-alanyl- -D- tetracosenoate D-mannosyl-N 1-phosphate hydroxyicosanoyl- hydroxyoctadec- oxohexacos- a malonyl-[acp] IMP HMPREF3015_RS09665 HMPREF3015_RS05515 HMPREF3015_RS05515 5-methoxy-6-methylbenzimidazolyl HMPREF3015_RS25665 lipid II (meso long-chain fatty long-chain fatty fructose-bisphosphate bifunctional ADP-dependent HMPREF3015_RS19690 bifunctional 4-methyl-5-(2- 2-[(2R,5Z)-2-carboxy- HMPREF3015_RS25385 glutamyl-meso-2,6- -(N-acetyl-D- [acp] bifunctional UDP-3-O- 11-enoyl-[acp]bifunctional UDP-3-O- 7-enoyl-[acp] malonyl-[acyl- [+ 2 isozymes] adenosylcobamide biosynthesis diaminopimelate aldolase: 3-oxoacyl-ACP [+ 3 isozymes] adenosylcobinamide phosphooxyethyl) 4-methylthiazol-5(2H)- thiamine phosphate D-glucopyranose diaminopimeloyl- acid--CoA ligase: acid--CoA ligase: glucosaminyl) [3-hydroxymyristoyl] NAD(P)H-hydrate RS20070 HMP-PP HMP-PP ATP biosynthesis D-galactopyranuronate a chitodextrin containing) endo-beta-N- [3-hydroxymyristoyl] reductase FabG: carrier protein] O- 5'-nucleotidase: thiazole ylidene]ethyl phosphate from adenosylcobinamide-GDP asn D-alanyl-D-alanine) monofunctional HMPREF3015_RS21750 HMPREF3015_RS21750 -asparagine HMPREF3015_RS18455 dehydratase/NAD(P) kinase/adenosylcobinamide- synthase: asparagine--tRNA ligase: 2 acetylglucosaminidase: N-acetylglucosamine N-acetylglucosamine methyltransferase BioC: 5-methoxy-6- hexokinase: pentapeptide biosynthetic peptidoglycan [+ 3 isozymes] [+ 3 isozymes] a glycopeptide- fructose-bisphosphate H-hydrate epimerase: HMPREF3015_RS11825 HMPREF3015_RS04825 phosphate HMPREF3015_RS25410 HMPREF3015_RS11345 an L-asparaginyl- a nascent peptidoglycan HMPREF3015_RS12490N-acetyl-D- deacetylase/3-hydroxyacyl- deacetylase/3-hydroxyacyl- a (3R,7Z)-3- HMPREF3015_RS04675 thiamine phosphate thiamine phosphate methylbenzimidazole thiamine HMPREF3015_RS12785 transglycosylase: D-mannosyl- aldolase: HMPREF3015_RS10825 a malonyl-[acp] guanylyltransferase: nicotinate-nucleotide-- [tRNA Asn ] with (L-alanyl-γ-D- (Z)-15- glucosamine- ACP dehydratase: ACP dehydratase: hydroxyhexacos- ADP HMPREF3015_RS22785 AMP diphosphate AMP diphosphate linoleoyl-CoA 4 synthase: synthase: phosphate Asn di-trans,octa-cis N -N-acetyl- HMPREF3015_RS02790 methyl ester inosine HMPREF3015_RS16580 dimethylbenzimidazole tRNA D-glucopyranose aldehydo-D- glutamyl-meso-2,6- tetracosenoyl-CoA asparagine HMPREF3015_RS04005 HMPREF3015_RS04005 NADH 7-enoyl-[acp] a 7,8-dihydrofolate serine a 5-methyltetrahydrofolate F0F1 ATP synthase: a chitodextrin a (2E,11Z)- HMPREF3015_RS25385 HMPREF3015_RS25385 phosphoribosyltransferase: 6-phosphate galacturonate -undecaprenyl D-glucosamine D-glyceraldehyde DHAP a (2E)-icos- hydroxymethyltransferase: glyA adenosylcobinamide- HMPREF3015_RS18305 diaminopimeloyl- octadeca-2,11- RS03540 gcv system: thiamine phosphate thiamine phosphate 5-methoxy-6-HMPREF3015_RS16575 glucose-6-phosphate diphosphate 2-enoyl-[acp] GDP HMPREF3015_RS18310 glucuronate isomerase: D-alanyl-D-alanine) dienoyl-[acp] HMPREF3015_RS23630 synthase: synthase: methylbenzimidazole isomerase: HMPREF3015_RS18315 HMPREF3015_RS17540 pentapeptide HMPREF3015_RS25410 HMPREF3015_RS25410 ribotide phosphate thiamine HMPREF3015_RS16410 adenosylcobinamide- HMPREF3015_RS18320 bifunctional a (6S)-5- asp D-tagaturonate GDP ribazoletransferase: thiamine diphosphokinase: aspartate--tRNA ligase: F6P HMPREF3015_RS18325 beta-N- a nascent peptidoglycan a peptidoglycan α,ω-9Z- peptidoglycan peptidoglycan trans,octacis a (3R,6Z)-3- a guanine 527 a (5Z)-3- methylenetetrahydrofolate formyltetrahydrofolate thiamine 18-hydroxyoleate GDP-α-D- thiamine phosphate HMPREF3015_RS16570 HMPREF3015_RS15490 HMPREF3015_RS17695 an L-aspartyl- HMPREF3015_RS18330 acetylhexosaminidase: with (L-alanyl-γ-D- with (L-alanyl-γ-D- octadecenedioate tetrapeptide, tetrapeptide, -decaprenyl hydroxyoctadec- MEP CTP in 16S rRNA oxotetracos- a protein RS07775 dehydrogenase/ phosphate D-arabinose degradation I mannose dIDP methylenetetrahydrofolate 5-formyltetrahydrofolate Coα-[α-(5-methoxy-6- [tRNA asp ] 6-phosphofructokinase: HMPREF3015_RS18340 HMPREF3015_RS21485 long-chain fatty long-chain-fatty- glycan chain 1 glycan chain 2 phosphate 6-enoyl-[acp] 16S rRNA 5-enoyl-[acp] thymidylate synthase: glutamyl-meso-2,6- glutamyl-meso-2,6- L,D-transpeptidase: polyprenol bifunctional UDP-3-O- 2-C-methyl-D- reductase [NAD(P)H]: methenyltetrahydrofolate cyclo-ligase: thiamine-phosphate kinase: methylbenzimidazolyl)]- thiamine tRNA asp HMPREF3015_RS17195 HMPREF3015_RS18345 [+ 6 isozymes] acid--CoA ligase: acid--CoA ligase: (guanine(527)-N(7))- 3-oxoacyl-ACP HMPREF3015_RS07170 thiamine-phosphate kinase: N,N'- N,N',N''- diaminopimeloyl-D- diaminopimeloyl-D- HMPREF3015_RS19755 monophosphomannose [3-hydroxymyristoyl] erythritol 4-phosphate protein disulfide-isomerase: nucleoside- cyclohydrolase: HMPREF3015_RS04175 β diphosphate [+ 2 isozymes] D-fructuronate D-arabinopyranose L,D-transpeptidase: HMPREF3015_RS21750 HMPREF3015_RS16270 methyltransferase RsmG: reductase FabG: HMPREF3015_RS08520 folate transformations I HMPREF3015_RS12905 HMPREF3015_RS12905 Co -adenosylcobamide diacetylchitobiose triacetylchitotriose alanine) tetrapeptide alanine) tetrapeptide L,D-transpeptidase: synthase: N-acetylglucosamine cytidylyltransferase: HMPREF3015_RS11420 diphosphate kinase: HMPREF3015_RS13955 β V-type ATP synthase: HMPREF3015_RS19755 HMPREF3015_RS11825 a 5,10- a 5,10- 5'-phosphate -D-fructose 1,6- [+ 3 isozymes] [+ 3 isozymes] 7 HMPREF3015_RS23640 thiamine HMPREF3015_RS05945 beta-hexosaminidase: peptidoglycanHMPREF3015_RS11065 HMPREF3015_RS09935 deacetylase/3-hydroxyacyl- HMPREF3015_RS01325 an N - a (3R,5Z)-3- HMPREF3015_RS11625 methylenetetrahydrofolate methenyltetrahydrofolate alpha-ribazole bisphosphate L-fucose isomerase: L,D-transpeptidase: ω-carboxy- trans,octacis- gln RS09780 gln thiamine diphosphate HMPREF3015_RS05950 HMPREF3015_RS18525 a nascent peptidoglycan 18-hydroxyoleoyl- ACP dehydratase: [+ 2 isozymes] methylguanine 527 hydroxytetracos- a protein a tetrahydrofolate diphosphate HMPREF3015_RS06075 HMPREF3015_RS11065 AMP diphosphate AMP diphosphate (9Z)-octadec- D-ala DAP-DAP GDP decaprenylphospho- 4-(cytidine 5'- bifunctional phosphatase: with L,D cross links dITP tyr HMPREF3015_RS05955 [+ 6 isozymes] D-ala CoA crosslink β a (2E,6Z)- HMPREF3015_RS04005 diphospho)-2-C- in 16S rRNA 5-enoyl-[acp] NAD biosynthesis I (from aspartate) 2-methyladeninyl HMPREF3015_RS16565 fructose-bisphosphate D-ribulose fucose degradation (meso-diaminopimelate 9-enoyl-CoA -D-mannose methylenetetrahydrofolate Coα-[α-(5-methoxy-6- tyrosine--tRNA ligase: HMPREF3015_RS05960 N-acetyl-D- octadecadienoyl- methyl-D-erythritol formate-- acyl carrier protein activation + + dehydrogenase/ adenosylcobamide biosynthesis HMPREF3015_RS01655 aldolase: HMPREF3015_RS05965 glucosamine containing) Na RS23555 Na tetrahydrofolate ligase: methyl-benzimidazolyl)]- an L-tyrosyl- [acp] methenyltetrahydrofolate from adenosylcobinamide-GDP Tyr HMPREF3015_RS18455 β asp phosphopantothenate biosynthesis I Coβ-adenosylcobamide [tRNA ] ATP -L-fucopyranose HMPREF3015_RS18220 adeninyl adenosylcobamide an apo acyl- Tyr [+ 2 isozymes] cyclohydrolase: 2-methyladenine coenzyme A a tRNA L-aspartate oxidase: HMPREF3015_RS13955 biosynthesis from carrier protein D-ribulose 4-hydroxy-2- a guanine 966 an (11Z)-3- a (5Z)-3- nicotinate-nucleotide-- 4'-phosphopantetheinyl a sulfurated O-acetyl-L- MoO - + + HMPREF3015_RS05840 3-methyl-2- 7-hydroxylaurate decanoate an oligopeptide methanethiol 2 Na RS03550 Na 10 adenosylcobinamide-GDP 1-phosphate SAM dethiobiotin oxoglutarate in 16S rRNA oxooctadec- oxododec- 10 transferase: dermatan sulfate α-L-fucopyranose homoserine molybdopterin ATP IDP oxobutanoate an N - an N - dimethylbenzimidazole triose-phosphate [sulfur carrier] long-chain fatty dipeptidyl carboxypeptidase 16S rRNA 2-iminosuccinate HMPREF3015_RS13675 bifunctional biotin synthase/ long-chain fatty O-acetylhomoserine bifunctional 4-hydroxy- 11-enoyl-[acp] 5-enoyl-[acp] 3-methyl-2-oxobutanoate formyltetrahydrofolate formyltetrahydrofolate phosphoribosyltransferase: isomerase: degradation I (bacterial) cofactor 3-oxoacyl-ACP 3-oxoacyl-ACP a holo acyl- L-fucose isomerase: acid--CoA ligase: acid--CoA ligase: II: HMPREF3015_RS15275 sulfhydrylase: 2-oxoglutarate aldolase/ MobA protein: (guanine(966)-N(2))- nucleoside- adenine HMPREF3015_RS16575 5-methoxybenzimidazolyl 3',5'-ADP HMPREF3015_RS11645 adenosylmethionine--8- quinolinate synthase NadA: hydroxymethyltransferase: carrier protein D-glyceraldehyde HMPREF3015_RS21750 HMPREF3015_RS21750 HMPREF3015_RS25260 methyltransferase RsmD: reductase FabG: reductase FabG: + + nicotinate-nucleotide-- adenosylcobamide biosynthesis a tRNA Trp DHAP dermatan sulfate HMPREF3015_RS06075 amino-7-oxononanoate dipeptidyl carboxypeptidase HMPREF3015_RS00925 2-dehydro-3-deoxy- diphosphate kinase: Na RS05005 Na HMPREF3015_RS10660 HMPREF3015_RS25605 gcv system: 2-methyladenine tryptophan--tRNA ligase: 3-phosphate HMPREF3015_RS01355 HMPREF3015_RS11825 HMPREF3015_RS11825 dimethylbenzimidazole from adenosylcobinamide-GDP transaminase: [+ 3 isozymes] [+ 3 isozymes] II: HMPREF3015_RS04195 [+ 2 isozymes] phosphogluconate MobA protein: an N 2 - a (3R,11Z)-3- a (3R,5Z)-3- HMPREF3015_RS11625 HMPREF3015_RS23630 ribotide phosphate HMPREF3015_RS14460 an L-tryptophanyl- DHAP glycolaldehyde L-fuculose adenylyl methionine synthase: bifunctional phosphoribosyltransferase: glyceraldehyde-3- HMPREF3015_RS04690 7-hydroxylauroyl- aldolase: HMPREF3015_RS24465 methylguanine 966 hydroxyoctadec- hydroxydodec- 2-dehydropantoate formyltetrahydrofolate Trp β a dipeptide a peptide acetate met quinolinate 5-methoxybenzimidazole [tRNA ] phosphate dehydrogenase: 4-deoxy- -D-gluc- AMP diphosphate diphosphate AMP decanoyl-CoA HMPREF3015_RS06170 molybdenum HMPREF3015_RS09665 deformylase: methylenetetrahydrofolate HMPREF3015_RS16575 an unsulfurated CoA in 16S rRNA 11-enoyl-[acp] 5-enoyl-[acp] ITP adenosylcobinamide- nicotinate-nucleotide-- 4-enuronosyl- met 5'-deoxyadenosine biotin cofactor L-fucose RS03265 L-fucose nicotinate-nucleotide [+ 2 isozymes] bifunctional dehydrogenase/ a (6S)-5- adenine ribotide trp HMPREF3015_RS04200 [sulfur carrier] pyruvate glyoxylate HMPREF3015_RS20490 GDP ribazoletransferase: dimethylbenzimidazole (1,3)-N-acetyl-D- diphosphorylase methylenetetrahydrofolate methenyltetrahydrofolate formyltetrahydrofolate phosphate HMPREF3015_RS16570 phosphoribosyltransferase: galactosamine 4-sulfate L-fuculose α α 13-DPG (carboxylating): β dehydrogenase/ cyclohydrolase: adenosylcobinamide- Co -[ -(2- glycolate 1-phosphate -alanine (R)-pantoate 5-formyltetrahydrofolate HMPREF3015_RS16575 HMPREF3015_RS14185 methenyltetrahydrofolate HMPREF3015_RS13955 methyladenin-9-yl)]-Co 5-methoxybenzimidazole a very-long- a (7Z,10Z,13Z,16Z adenine 1518 / (4S)-4-hydroxy- a cytidine 1402 a (6Z)-3- a (9Z)-3- L-fucose RS06055 L-fucose cyclo-ligase: GDP ribazoletransferase: 5-methylbenzimidazolyl phosphoglycerate kinase: 16-hydroxypalmitate octanoate (R)-NADPHX acetyl-CoA β ribotide phosphate ,19Z)-3-oxodocosa- 1519 oxooctadec- cyclohydrolase: HMPREF3015_RS16570 -adenosylcobamide adenosylcobamide biosynthesis thr chain fatty acid adenine in 16S rRNA 2-oxoglutarate in 16S rRNA oxooctacos- NaMN HMPREF3015_RS13955 HMPREF3015_RS04175 Coα-[α-(adenin- 5'-phosphate threonine--tRNA ligase: HMPREF3015_RS00485 4-deoxy-β-D-gluc-4- long-chain fatty long-chain-fatty- long-chain fatty 7,10,13,16,19-pentaenoyl-[acp] 16S rRNA (adenine(1518)- bifunctional 4-hydroxy- bifunctional ADP-dependent 16S rRNA 6-enoyl-[acp] 9-enoyl-[acp] acetyl-CoA carboxylase pantoate--beta- adenosylcobinamide- from adenosylcobinamide-GDP serine 9-yl)]-Coβ- alpha-ribazole HMPREF3015_RS21250 enuronosyl-(1,3)-N- (S)-lactaldehyde DHAP acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: 3-oxoacyl-ACP N(6)/adenine(1519)-N(6))- 2-oxoglutarate aldolase/ NAD(P)H-hydrate (cytosine(1402)-N(4))- 3-oxoacyl-ACP 3-oxoacyl-ACP biotin carboxyl carrier nicotinate-nucleotide alanine ligase: GDP ribazoletransferase: an L-threonyl- 3-phospho- K(+)- hydroxymethyltransferase: glyA bifunctional a 5,10- adenosylcobamide phosphatase: 5-methylbenzimidazole NaMN Thr heparan sulfate degradation acetyl-D-galactosamine HMPREF3015_RS21750 HMPREF3015_RS16270 HMPREF3015_RS21750 reductase FabG: dimethyltransferase RsmA: 2-dehydro-3-deoxy- dehydratase/NAD(P) methyltransferase RsmH: reductase FabG: reductase FabG: protein subunit: adenylyltransferase: HMPREF3015_RS11300 HMPREF3015_RS16570 [tRNA ] D-glycerate K + transporting K + methylenetetrahydrofolate methenyltetrahydrofolate nicotinate-nucleotide-- Thr glycosyl hydrolase HMPREF3015_RS11825 HMPREF3015_RS11825 HMPREF3015_RS11825 5'-phosphate HMPREF3015_RS16565 α α a tRNA [+ 3 isozymes] [+ 3 isozymes] [+ 3 isozymes] 6 HMPREF3015_RS199851518 phosphogluconate H-hydrate epimerase: 4 HMPREF3015_RS07980 HMPREF3015_RS00575 HMPREF3015_RS05390 α α Co -[ -(5- 2,3- a (3R,7Z,10Z,13Z,16Z N -dimethyladenine an N - a (3R,6Z)-3- a cis-delta9-3- ATPase dehydrogenase/ alpha-ribazole Co -[ -(2- dimethylbenzimidazole Macromolecule Modification family 88: methoxybenzimidazolyl) diphosphoglycerate- heparan sulfate 6 1519 aldolase: HMPREF3015_RS10825 1402 [+ 3 isozymes] nicotinate adenine methyladenin-7-yl)]-Co 16-hydroxypalmitoyl- diphosphate a very-long-chain ,19Z)-3-hydroxydocosa- /N -dimethyladenine methylcytidine hydroxyoctadec- hydroxyC28:1- (R)-pantothenate methenyltetrahydrofolate phosphatase: ]-Coβ-adenosylcobamide phosphoribosyltransferase: heparitin sulfate lyase: HMPREF3015_RS03780 AMP diphosphate AMP diphosphate AMP octanoyl-CoA HMPREF3015_RS06170 (S)-NADPHX malonyl-CoA dinucleotide a 5,10- β-adenosylcobamide dependent CoA fatty acyl-CoA 7,10,13,16,19-pentaenoyl-[acp] in 16S rRNA in 16S rRNA 6-enoyl-[acp] [acp] cyclohydrolase: HMPREF3015_RS16565 5'-phosphate HMPREF3015_RS16575 4-deoxy-L-threo-hex- N-acetyl-D- predicted a 5-methyltetrahydrofolate Coα-[α-(adenin- 5-methylbenzimidazole phosphoglycerate queuosine biosynthesis β HMPREF3015_RS19195 pyruvate glyoxylate NAD+ synthetase, pantothenate kinase: methylenetetrahydrofolate HMPREF3015_RS13955 NAD salvage pathway I alpha-ribazole 4-deoxy- -L-erythro-hex- 4-enopyranuronate galactosamine ATP-driven NAD(+) synthase: ribotide phosphate mutase: gpmA + + glutamine dependent: HMPREF3015_RS10915 7-yl)]-Coβ- 4-enopyranuronosyl-(1,4) K K HMPREF3015_RS10085 phosphatase: ser transporter methylenetetrahydrofolate adenosylcobamide adenosylcobinamide- serine--tRNA ligase: 2,3- preQ HMPREF3015_RS10085 -D-N-sulfoglucosamine 6 (R)-4'- + HMPREF3015_RS16565 0 an N -L- an [amino group carrier protein]- of K+ reductase [NAD(P)H]: NAD α α GDP ribazoletransferase: HMPREF3015_RS11285 an L-seryl- diphosphoglycerate- NADPH-dependent 7- β a pseudouridine 1915 adenine 1618 5-hydroxybenzimidazolyl Co -[ -(5- 4-deoxy- -L-erythro-hex- α 37 a cis-delta21-3- L(or D)-O- + phosphopantothenate NAD(+) diphosphatase: -linolenate threonylcarbamoyladenine C-terminal-γ-(L-glutamate 5- formate CTP (S)-NADPHX 3',5'-ADP NAD HMPREF3015_RS08520 [tRNA ser ] cyano-7-deazaguanine in 23S rRNA benzimidazolyl adenosylcobamide adenosylcobalamin biosynthesis adenosylcobamide biosynthesis methoxybenzimidazolyl) HMPREF3015_RS16570 dependent 4-enopyranuronosyl-(1,4) sucrose degradation III (sucrose invertase) IMP in 23S rRNA oxo-C40:1-[acp] phosphoserine glycine glycine HMPREF3015_RS14275 Coα-[α-(5-methylbenzimidazolyl) a tRNA ser reductase QueF: long-chain-fatty- in tRNA tRNA semialdehyde-2-yl)-L-glutamate 23S rRNA anaerobic ribonucleoside- bifunctional ADP-dependent 23S rRNA RS14305 biosynthesis from from adenosylcobinamide-GDP I NAD+ synthetase, from adenosylcobinamide-GDP ]-Coβ-adenosylcobamide phosphoglycerate -D-N-sulfoglucosamine N-acetyl-gamma-glutamyl- 3-oxoacyl-ACP phosphoserine 3'(2'),5'-bisphosphate betaine betaine ]-Coβ-adenosylcobamide HMPREF3015_RS14155 bifunctional acid--CoA ligase: threonylcarbamoyladenosine (pseudouridine(1915)-N(3) triphosphate reductase: NAD(P)H-hydrate (adenine(1618)-N(6))- adenosylcobinamide-GDP glutamine dependent: mutase: gpmA hydrolase: sucrose phosphate reductase: reductase FabG: phosphatase SerB: nucleotidase: 5-hydroxybenzimidazole NaMN 5'-phosphate preQ phosphoribosylaminoimidazolecarboxamide HMPREF3015_RS16270 dehydratase: )-methyltransferase RlmH: HMPREF3015_RS20595 dehydratase/NAD(P) methyltransferase RlmF: 5,6-dimethylbenzimidazole HMPREF3015_RS10085 2-phospho- 1 HMPREF3015_RS11355 HMPREF3015_RS01070 HMPREF3015_RS11825 HMPREF3015_RS17585 HMPREF3015_RS21195 menaquinol-11 biosynthesis benzimidazole nicotinate-nucleotide-- alpha-ribazole formyltransferase/IMP cyclohydrolase [+ 3 isozymes] 6 3 HMPREF3015_RS14175 H-hydrate epimerase: 6 HMPREF3015_RS00945 menaquinol-7 biosynthesis nicotinate-nucleotide-- nicotinate adenine D-glycerate a cyclic N -L-HMPREF3015_RS03535 an [amino group carrier protein]- an N - anaerobic ribonucleoside- an N - a cis-delta21-3- glycine glycine nicotinate-nucleotide-- NMN dimethylbenzimidazole tRNA guanosine(34) N-sulfo-D-glucosamine PurH: HMPREF3015_RS08475 1915 HMPREF3015_RS10825 1618 RS14310 menaquinol-10 biosynthesis phosphatase: invertase: threonylcarbamoyladenosine C-terminal-γ-(5-phospho- methylpseudouridine triphosphate reductase: methyladenine hydroxyC40:1- serine betaine betaine all-trans- dimethylbenzimidazole dimethylbenzimidazole dinucleotide phosphoribosyltransferase: phosphopyruvate transglycosylase Tgt: FAICAR AMP diphosphate α-linolenoyl-CoA AMP 2-carboxy-1,4- 2-carboxy-1,4- HMPREF3015_RS16565 pro HMPREF3015_RS18890 37 in tRNA L-glutamyl)-L-glutamate in 23S rRNA HMPREF3015_RS05470 NADPH in 23S rRNA [acp] undecaprenyl phosphoribosyltransferase: phosphoribosyltransferase: HMPREF3015_RS16575 proline--tRNA ligase: hydratase: naphthoquinol naphthoquinol nicotinate-nucleotide all-trans- Coα-[α-(5-methylbenzimidazolyl) HMPREF3015_RS17600 dCTP 1,4-dihydroxy-2-naphthoate HMPREF3015_RS16575 5-hydroxybenzimidazole 2-carboxy-1,4- HMPREF3015_RS24645 an L-prolyl- HMPREF3015_RS12740 a 7-aminomethyl-7- diphosphate 1,4-dihydroxy-2-naphthoate HMPREF3015_RS16575 α-ribazole adenylyltransferase: decaprenyl β β ribotide phosphate ]-Co -adenosylcobamide Pro 34 -D-fructofuranose D-glucopyranose 2+ 2+ polyprenyltransferase: benzimidazole polyprenyltransferase: HMPREF3015_RS05390 naphthoquinol [tRNA ] phosphoenol deazaguanosine Cd RS23675 Cd 5'-phosphate diphosphate 1,4-dihydroxy-2-naphthoate Pro ribotide phosphate HMPREF3015_RS05380 a tRNA in tRNA D-glucosamine 6 HMPREF3015_RS05380 adenosylcobinamide- pyruvate pectin degradation I hexokinase: an N -L- 2-phospho-4-(cytidine 5'- sn-glycero-3- adenine 2030 demethylmenaquinol-7 adenosylcobinamide- polyprenyltransferase: a sulfurated pristanate formate UTP a cis-delta19-3- a [protein]- DMKH2-11 GDP ribazoletransferase: S-adenosylmethionine:tRNA threonylcarbamoyladenine 37 diphospho)-2-C-methyl-D-erythritol a purine arg L-homoserine adenosylcobinamide- NaMN nicotinamide pyruvate kinase: hexokinase: HMPREF3015_RS12785 arsenate phosphoethanolamine in 23S rRNA L-histidine RS11510 GDP ribazoletransferase: HMPREF3015_RS05380 a methyl-esterified [sulfur carrier] 2-C-methyl-D-erythritol ribonucleoside oxo-C38:1-[acp] histidine kinase: RS20730 GDP ribazoletransferase: HMPREF3015_RS16570 ribosyltransferase-isomerase: in tRNA long-chain fatty glycerophosphodiester arginase: 23S rRNA 2+ 2+ bifunctional α α DMKH2-10 HMPREF3015_RS15150 homogalacturonan HMPREF3015_RS12785 D-glucopyranose tRNA (N(6)-L- anaerobic ribonucleoside- Cd RS04910 Cd bifunctional HMPREF3015_RS16570 HMPREF3015_RS16570 Co -[ -(5- HMPREF3015_RS14905 acid--CoA ligase: 2,4-cyclodiphosphate purine-nucleoside phosphodiesterase: (adenine(2030)-N(6))- 3-oxoacyl-ACP homoserine O- HMPREF3015_RS15615 demethylmenaquinone β 6-phosphate threonylcarbamoyladenosine(37) triphosphate reductase: HMPREF3015_RS24735 demethylmenaquinone Coα-[α-(benzimidazolyl) adenosylcobalamin hydroxybenzimidazolyl)]-Co - phenylalanine--tRNA HMPREF3015_RS21750 synthase: phosphorylase: HMPREF3015_RS02505 methyltransferase RlmJ: reductase FabG: succinyltransferase: thiamine diphosphate methyltransferase/2- nicotinate bifunctional pyruvate tRNA preQ1(34) S- -C(2))- methylthiotransferase HMPREF3015_RS20595 arginase: histidine kinase: methyltransferase/2- ]-Coβ-adenosylcobamide 5'-phosphate adenosylcobamide 5'-phosphate ligase subunit alpha: glucose-6-phosphate HMPREF3015_RS11440 HMPREF3015_RS12900 HMPREF3015_RS11825 HMPREF3015_RS09115 biosynthesis II (Bacillus) demethylmenaquinone [+ 3 isozymes] [+ 4 isozymes] 6 HMPREF3015_RS15585 HMPREF3015_RS04555 methoxy-6-polyprenyl- phosphoribosyltransferase: adenosylmethionine a homogalacturonan MtaB: HMPREF3015_RS16275a 2-methylsulfanyl-N 6 -L- anaerobic ribonucleoside- HMPREF3015_RS02755 an N - a cis-delta19-3- a [protein]- methoxy-6-polyprenyl- 5'-phosphate alpha-ribazole methyltransferase/2- HMPREF3015_RS00470 isomerase: an unsulfurated 2-C-methyl-D-erythritol- ribose-1-arsenate a purine base sn-glycerol O-succinyl-L- a cation RS22755 a cation 1,4-benzoquinol alpha-ribazole HMPREF3015_RS05280 ribosyltransferase- met 5'-deoxyadenosine threonylcarbamoyladenine 37 CMP ethanolamine triphosphate reductase: L-ornithine urea methyladenine 2030 hydroxyC38:1- N-phospho- 1,4-benzoquinol HMP-PP alpha-ribazole nicotinate phosphatase: methoxy-6-polyprenyl- phenylalanine--tRNA exo-poly-alpha-D- HMPREF3015_RS16410 [sulfur carrier] AMP diphosphate pristanoyl-CoA 2,4-cyclodiphosphate 3-phosphate homoserine RS09735 methylase UbiE: phosphatase: phe isomerase QueA: in tRNA HMPREF3015_RS05470 in 23S rRNA [acp] L-histidine RS20150 methylase UbiE: thiamine phosphate phosphatase: HMPREF3015_RS16565 1,4-benzoquinol ligase subunit beta: galacturonosidase: HMPREF3015_RS04060 HMPREF3015_RS16565 HMPREF3015_RS05735 F6P dUTP HMPREF3015_RS04060 synthase: HMPREF3015_RS16565 folate polyglutamylation Coα-[α-(5-hydroxybenzimidazolyl) methylase UbiE: HMPREF3015_RS25275 Pentose Phosphate Pathways HMPREF3015_RS04395 an L-phenylalanyl- an epoxyqueuosine 34 a cation RS06515 a cation HMPREF3015_RS25385 Coα-[α-(benzimidazolyl) adenosylcobalamin ]-Coβ-adenosylcobamide HMPREF3015_RS04060 Phe exo-poly-alpha-D- menaquinol-11 menaquinol-7 [tRNA ] in tRNA L-arabinose degradation I thiamine phosphate ]-Coβ-adenosylcobamide a tetrahydrofolate a tRNA Phe pentose phosphate galacturonosidase: 3-aci- 5-hydroxybenzimidazole bis(guanylyl molybdenum aci-nitroethane a (6S)-5- a [protein] Ser/Thr L-canavanine a 3-oxoicosanoyl- a cis-delta17-3- MEP synthase: thioredoxin pathway menaquinol-10 HMPREF3015_RS04405 nitropropanoate glu asp cofactor) biosynthesis pathway (oxidative branch) I formyltetrahydrofolate ribotide phosphate ATP H O [acp] oxo-C36:1-[acp] RS02275 α L-arabinopyranose nitronate monooxygenase: nitronate monooxygenase: 2 HPr kinase: arginase: 1-deoxy-D-xylulose- a cation RS23670 a cation RS01635 HMPREF3015_RS25410 serine -D-galacturonosy- bifunctional alpha-ribazole thiamine bifunctional formate-- MoO - D-glucopyranose HMPREF3015_RS14210 HMPREF3015_RS14210 ATPase: HMPREF3015_RS11270 HMPREF3015_RS24735 3-oxoacyl-ACP 3-oxoacyl-ACP 2 a queuosine 34 (1->4)-α-D-galacturonate L-arabinose isomerase: folylpolyglutamate synthase/ aspartate 4-decarboxylase: 5-phosphate lipoate biosynthesis an oxidized folylpolyglutamate synthase/ hydroxymethyltransferase: glyA tetrahydrofolate ligase: 6-phosphate phosphatase: HMPREF3015_RS09635 reductase FabG: reductase FabG: phosphate molybdopterin molybdopterin NADP + -dependent HMPREF3015_RS09630 nitronate monooxygenase: serine/threonine reductoisomerase: di-trans,poly-cis-undecaprenyl menaquinol-6 biosynthesis thioredoxin HMPREF3015_RS18220 in tRNA nitronate monooxygenase: dihydrofolate synthase: HMPREF3015_RS16565 arginase: HMPREF3015_RS18230 RS14380 and incorporation I dihydrofolate synthase: cofactor [+ 5 isozymes] HMPREF3015_RS11825 HMPREF3015_RS11825 phosphate biosynthesis thiamine-phosphate kinase: met glucose-6-phosphate L-ribulose HMPREF3015_RS13485 HMPREF3015_RS13485 HMPREF3015_RS09320 (2S,3R,4S,5R)-2-(5-hydroxy- protein kinase: HMPREF3015_RS02755 a (3R)-3- a cis-delta17-3- 1-deoxy-D-HMPREF3015_RS05430 HMPREF3015_RS09320 a 5,10- menaquinol-9 biosynthesis methionine--tRNA ligase: [unspecified [unspecified + a cation RS06545 a cation bis(molybdenum dehydrogenase: 4-deoxy-L-threo-hex- a (6S)-5- 1,3-benzodiazol-1-yl)-5- H phosphate ADP HMPREF3015_RS09310 HMPREF3015_RS12905 methylenetetrahydrofolate 10 an L-methionyl- D-galactopyranuronate degradation nitrite 3-oxopropanoate degradation nitrite acetaldehyde urea L-canaline hydroxyicosanoyl- hydroxyC36:1- ala xylulose 5- (2E,6E)-farnesyl demethylmenaquinol-6 an octanoyl-[acp] an N - cofactor) HMPREF3015_RS24305 4-enopyranuronate formyltetrahydrofolate a [protein] (L-serine/L- RS16740 IPP [elongator 6-phosphoHMPREF3015_RS22670 (hydroxymethyl)oxolane-3,4-diol [acp] [acp] phosphate RS13680 diphosphate bifunctional thioredoxin- bifunctional formyltetrahydrofolate products] products] thiamine a tetrahydrofolate demethylmenaquinol-9 elongator Met threonine) phosphate lipoate-protein ligase B: disulfide reductase: MobA protein: tRNA ] D-glucono- lipoprotein posttranslational demethylmenaquinone folylpolyglutamate synthase/ bifunctional Met di-trans,octa-cis diphosphate HMPREF3015_RS23685 bifunctional HMPREF3015_RS25260 tRNA 1,5-lactone modification a cation RS25290 a cation methyltransferase/2- a [lipoyl-carrier protein] HMPREF3015_RS11165 dihydrofolate synthase: folylpolyglutamate synthase/ L-ribulose 5-phosphate RS05460 -undecaprenyl demethylmenaquinone MobA protein: methoxy-6-polyprenyl- N 6 -octanoyl-L-lysine HMPREF3015_RS09320 dihydrofolate synthase: 6-phosphogluconolactonase: a [prolipoprotein]- a [2-oxoglutarate- N-acetyl-D- (R)-methylmalonyl- 4-(cytidine 5'- diphosphate methyltransferase/2- HMPREF3015_RS24465 gellan degradation (1,4)-β-D-xylan degradation a peptidoglycan succinate a single a ribonucleoside a 3-oxopimeloyl- a cis-delta15-3- long chain a phosphate 1,4-benzoquinol HMPREF3015_RS22675 L-ribulose-5-phosphate dehydrogenase a sulfurated galactosamine diphospho)-2-C- undecaprenyl- lipoyl synthase: a 5,10- HMPREF3015_RS09320 methoxy-6-polyprenyl- bis(guanylyl L-cysteine SAM stranded DNA triphosphate CoA polyphosphate monoester 4-epimerase: araD 6 lysozyme: [acp] methyl ester oxo-C34:1-[acp] methylase UbiE: a reduced 10 E2 protein] N - [sulfur carrier] ADP-forming succinate-- 6-phosphate methylmalonyl-CoA mutase: methyl-D-erythritol exopolyphosphatase: a cation RS02765 a cation RS04510 RS07555 diphosphate phosphatase: HMPREF3015_RS03965 methylenetetrahydrofolate an N - 1,4-benzoquinol molybdopterin D-gluconate prolipoprotein bifunctional DNA N-acetylglucosamine-6- 4-(cytidine 5'- alkaline phosphatase: guanylyl molybdenum thioredoxin NAD phosphorylation and dephosphorylation a tRNA Lys gellan a (1->4)-β-D-xylan octanoyl-L-lysine HMPREF3015_RS17785 CoA ligase subunit beta: HMPREF3015_RS22300 3-oxoacyl-ACP 3-oxoacyl-ACP HMPREF3015_RS11880 HMPREF3015_RS05745 HMPREF3015_RS04060 a [lipoyl-carrier formyltetrahydrofolate methylase UbiE: cofactor) lysine--tRNA ligase: 6-phosphate diacylglyceryl transferase: D-xylulose 5-phosphate lipoyl synthase: primase/helicase: phosphate deacetylase: diphospho)-2-C-methyl- HMPREF3015_RS10570 cofactor biosynthesis endo-1,4-beta-xylanase: lysozyme: HMPREF3015_RS05525 reductase FabG: reductase FabG: menaquinol-6 6 HMPREF3015_RS10550 HMPREF3015_RS03965 HMPREF3015_RS00865 methylmalonyl-CoA exopolyphosphatase: di-trans,octa-cis- protein]-N -[(R)- HMPREF3015_RS04060 HMPREF3015_RS16420 an L-lysyl- phosphogluconate a [2-oxoglutarate HMPREF3015_RS25490 D-erythritol kinase: HMPREF3015_RS11825 HMPREF3015_RS11825 alkaline phosphatase: MoO - NAD + HMPREF3015_RS18400 HMPREF3015_RS25150 mutase small subunit: RS04220 2 Lys unsaturated gellan an unsulfurated dehydrogenase [+ 7 isozymes] HMPREF3015_RS21830 a (3R)-3- a cis-delta15-3- HMPREF3015_RS06725 HMPREF3015_RS07350 undecaprenyl phosphate dihydrolipoyl]-L-lysine menaquinol-9 demethylmenaquinol-9 biosynthesis [tRNA ] dehydrogenase a [prolipoprotein]-S- 5'-deoxyadenosine met a N-acetylmuramoyl- phosphate ADP succinyl-CoA [+ 2 isozymes] 2-phospho-4-(cytidine long chain a cation RS02025 a cation molybdopterin tetrasaccharide [+ 2 isozymes] 6 N-acetyl-D- ssDNA/pppN(pN) D-galactosamine HMPREF3015_RS22305 demethylmenaquinol-6 biosynthesis I (NADP(+)-dependent, diacylglyceryl-L-cysteine a (1->4)-β-D-xylan [sulfur carrier] E2 protein] N pentapeptide- acetate 5'-diphospho)-2-C- hydroxypimeloyl- hydroxyC34:1- an alcohol lys hybrid polyphosphate cofactor MobA protein: thiamine salvage III all-trans- glycosyl hydrolase glucosamine n -1 6-phosphate succinyl-CoA RS03705 alkaline phosphatase: 2-carboxy-1,4- decarboxylating): oligosaccharide -lipoyl-L-lysine diphosphoundecaprenol methyl-D-erythritol [acp] methyl ester [acp] RS15180 HMPREF3015_RS25260 all-trans- nonaprenyl family 88: xylose degradation I HMPREF3015_RS10570 NAD kinase: 2-carboxy-1,4- naphthoquinol HMPREF3015_RS22665 lipoprotein beta-xylosidase: hexaprenyl diphosphate HMPREF3015_RS03780 a cation RS15595 a cation MobA protein: thiamine alkaline phosphatase: HMPREF3015_RS11585 naphthoquinol 1,4-dihydroxy-2-naphthoate D-ribulose signal peptidase: HMPREF3015_RS10475 guanylyl β β HMPREF3015_RS24465 thiamine diphosphokinase: HMPREF3015_RS07350 diphosphate 1,4-dihydroxy-2-naphthoate polyprenyltransferase: 5-phosphate HMPREF3015_RS17470 4-deoxy-L- -D-Glcp-(1->4) D-xylopyranose a [pyruvate adenosylcobinamide- an N-acetyl-α- D-glycero- -D- an oxidized RS04205 quinoxaline-2- α-ribazole a 3-oxoglutaryl- a cis-delta13-3- histidinol molybdenum polyprenyltransferase: HMPREF3015_RS05380 his threo-hex-4- -α-L-Rhap- β-D-xylopyranose xylose isomerase: dehydrogenase a sulfurated aryl-carrier protein D-glucosaminide glycerophosphoserine manno-heptose nitroaromatic HMPREF3015_RS15490 SAM carboxyl adenylate GDP GTP H O [acp] methyl ester oxo-C32:1-[acp] cofactor HMPREF3015_RS05380 demethylmenaquinol-9 histidine--tRNA ligase: an (S-diacyl-sn- enopyranuronate (1->3)-D-Glcp E2 protein] N 6 - [sulfur carrier] adenosylcobinamide- alpha-N- 2 glycerophosphodiester 1,7-bisphosphate compound thiamine NADP + a lipoprotein HMPREF3015_RS05500 acyl carrier protein: D-glycero-beta-D-manno- RS06805 demethylmenaquinol-6 HMPREF3015_RS19720 an L-histidyl- acetylglucosaminidase: GTPase HflX: 3-oxoacyl-ACP 3-oxoacyl-ACP NAD(P)H nitroreductase: histidinol dehydrogenase: RS17070 diphosphate glyceryl)-L-cysteinyl- signal peptide D-xylulose octanoyl-L-lysine lipoyl synthase: HMPREF3015_RS17210 GDP ribazoletransferase: phosphodiesterase: heptose 1,7-bisphosphate RS20010 [tRNA His ] [apolipoprotein] HMPREF3015_RS16570 HMPREF3015_RS11565 HMPREF3015_RS15790 HMPREF3015_RS02505 reductase FabG: reductase FabG: HMPREF3015_RS00530 HMPREF3015_RS10105 His HMPREF3015_RS03965a [pyruvate [+ 2 isozymes] 7-phosphatase: a tRNA xylulokinase: a quinoxaline-2- [+ 4 isozymes] [+ 4 isozymes] HMPREF3015_RS11825 HMPREF3015_RS11825 [+ 2 isozymes] D-mannose degradation an unsulfurated dehydrogenase [+ 4 isozymes] D-glycero-β-D-HMPREF3015_RS09240 a (3R)-3- a cis-delta13-3- a reduced RS04845 GMP adenosylcobalamin N-acetyl-α-D- + HMPREF3015_RS05505 5'-deoxyadenosine met 6 AMP carboxyl-[aryl- a non glycosylated phosphate GDP H sn-glycerol his [sulfur carrier] E2 protein] N ser manno-heptose hydroxyglutaryl- hydroxyC32:1- nitroaromatic an N-acyl-(S-diacyl- D-xylulose carrier protein] sugar acceptor glucosamine 3-phosphate D-mannopyranose Aldehyde Degradation -lipoyl-L-lysine 1-phosphate [acp] methyl ester [acp] compound a peptide 5-phosphate RS06530 sn-glyceryl)-L- 6-phosphate RS24130 RS01020 cysteinyl-[lipoprotein] mannose-6- gly superpathway of guanosine nucleotides de novo biosynthesis II Nucleoside and Nucleotide Biosynthesis phosphate isomerase: methylglyoxal degradation I undecaprenyl-diphospho-N a protein a (7Z)-3-oxo- superpathway of guanosine superpathway of adenosine nucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis I glycine--tRNA ligase: L-lactaldehyde a β-D-mannoside an [amino group carrier protein]-C- a cis-delta11-3- DHAP D-alanyl-D-alanine HMPREF3015_RS16465 -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine a purine a protein with incorrect hexadec-7- RS06520 nucleotides de novo biosynthesis I adenosine nucleotides HMPREF3015_RS03240 degradation (anaerobic) dGTP terminal-γ-(L-ornithyl)-L-glutamate Metabolic Regulator Biosynthesis Gly beta-mannosidase: ribonucleoside oxo-C30:1-[acp] a glycyl-[tRNA ] mannose-6- methylglyoxal D-glutamyl-L-lysyl- D-alanine undecaprenyldiphospho- acetylornithine ATP-dependent disulfide bonds enoyl-[acp] NAD(P)H-dependent de novo biosynthesis I UDP CTP deoxyguanosinetriphosphate HMPREF3015_RS25870 purine-nucleoside 3-oxoacyl-ACP 3-oxoacyl-ACP IMP Gly 6 37 phosphate isomerase: glycerol-3-phosphate ribonucleotide-diphosphate a tRNA N -L-threonylcarbamoyladenosine lactoylglutathione lyase: (S)-lactaldehyde muramoylpentapeptide beta-N- triphosphohydrolase: aminotransferase: phosphorylase: Clp protease protein disulfide-isomerase: RS15370 asp IMP beta-mannosidase: reductase FabG: reductase FabG: dehydrogenase: RS22310 RS02190 IMP reductase subunit alpha: ppGpp biosynthesis -modified tRNA biosynthesis HMPREF3015_RS20980 HMPREF3015_RS14050 lactaldehyde reductase: acetylglucosaminyltransferase: HMPREF3015_RS01065 proteolytic subunit: HMPREF3015_RS11420 asp IMP trehalose biosynthesis I HMPREF3015_RS08005 HMPREF3015_RS21475 HMPREF3015_RS12900 HMPREF3015_RS11825 HMPREF3015_RS11825 HMPREF3015_RS16415 CDP F6P (R)-S- HMPREF3015_RS07940 an [amino group carrier protein]- α-D-ribose- HMPREF3015_RS14535 a protein a (3R,7Z)-3- a cis-delta11-3- IMP dehydrogenase: HMPREF3015_RS08805 HMPREF3015_RS01110 ditrans,octacis-undecaprenyldiphospho- 2'-deoxyguanosine triphosphate β-D- γ a purine base adenylosuccinate synthase: lactoylglutathione (S)-propane- a non glycosylated C-terminal- -(L-glutamate 5- 1-phosphate sn-glycerol D-ala HMPREF3015_RS14520 adenylosuccinate synthase: ribonucleotide-diphosphate pppGpp D-glucopyranose thr UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- a peptide a peptide with correct hydroxy-hexadec- hydroxyC30:1- RS07230 IMP dehydrogenase: HMPREF3015_RS19705 ribonucleoside- bifunctional (p)ppGpp UDP-α-D-glucose 1,2-diol sugar acceptor mannopyranose semialdehyde-2-yl)-L-glutamate 3-phosphate HMPREF3015_RS19705 adenylo-succinate reductase subunit alpha: 6-phosphate threonylcarbamoyl- hydroxyacylglutathione L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine disulfide bonds 7-enoyl-[acp] [acp] HMPREF3015_RS14520 diphosphate reductase, synthetase/guanosine- bifunctional alpha,alpha- met HMPREF3015_RS08805 AMP synthase: hydrolase: adenylo-succinate adenosylcobalamin- 3',5'-bis(diphosphate) 3'- trehalose-phosphate methionine--tRNA ligase: RS06955 XMP adenylosuccinate lyase: HMPREF3015_RS11855 HMPREF3015_RS23635 RS14000 RS11005 dependent: ribonucleoside- pyrophosphohydrolase: HMPREF3015_RS24305 an L-methionyl- 2503 a 3,5,7,9,11,13,15- 2251 a (3R,5Z)-3- a 1-phosphatidyl- XMP HMPREF3015_RS11335 synthase (UDP-forming)/ adenine adenosylcobinamide- phenyl ribotide (5Z,8Z,11Z,14Z,17Z) coenzyme A an [amino group carrier protein]-C- guanosine a [protein]- HMPREF3015_RS16310 HMPREF3015_RS01470 [initiator tRNA Met ] threonylcarbamoyl- (R)-lactate a purine 2'- hepta-oxo- hydroxy-tetradec- 1D-myo-inositol ethylphosphate xanthosine-5'-phosphate:L- adenylosuccinate lyase: diphosphate reductase, trehalose-phosphatase: in 23S rRNA GDP phosphate -icosapentaenoate terminal-γ-(L-glutamyl)-L-glutamate in 23S rRNA L-tyrosine Met deoxyribonucleoside HMPREF3015_RS11335 dUDP adenosylcobalamin- HMPREF3015_RS09045 initiator tRNA AMP synthase: 23S rRNA adenosylcobinamide- long-chain-fatty- hexadecanoyl-[PKS-acp] 23S rRNA 5-enoyl-[acp] 4-phosphate alkaline phosphatase: RS07955 glutamine amido- xanthosine-5'-phosphate:L- bifunctional (p)ppGpp guanosine 3'-diphosphate α,α-trehalose purine-nucleoside aldo/keto reductase: 3-oxoacyl-ACP phosphatidylinositol-4- AMP dependent: (L-threonylcarbamoyl)HMPREF3015_RS04440 (adenine(2503)-C(2))- GDP ribazoletransferase: acid--CoA ligase: acetylglutamate kinase: (guanosine(2251)-2'-O)- HMPREF3015_RS07350 ligase (AMP-forming): glutamine amido- nucleoside- superpathway of 5-aminoimidazole synthetase/guanosine- 5'-triphosphate 3'- 6-phosphate Amino Acid Degradation Aromatic Compound Degradation phosphorylase: HMPREF3015_RS02320 reductase FabG: phosphate 5-kinase: HMPREF3015_RS16310 adenylate methyltransferase RlmN: HMPREF3015_RS16570 HMPREF3015_RS16270 HMPREF3015_RS07690 methyltransferase RlmB: HMPREF3015_RS04210 diphosphate kinase: ribonucleotide biosynthesis 3',5'-bis(diphosphate) 3'- HMPREF3015_RS18025 alkaline phosphatase: RS17365 ligase (AMP-forming): AMP diphosphatase: bifunctional alpha,alpha- HMPREF3015_RS10880 phenyl-Coβ- [+ 3 isozymes] an [amino group carrier protein]- 2-deoxy-α- HMPREF3015_RS12900 [+ 4 isozymes] HMPREF3015_RS20380 HMPREF3015_RS11825 a [protein]- RS18505 HMPREF3015_RS11625 pyrophosphohydrolase: N 6 -L- 9-hydroxy-3,5,7,11,13,15- 2-O- a (5Z)-3-oxo- a 1-phosphatidyl- HMPREF3015_RS10570 RS22055 HMPREF3015_RS04210 adenylate kinase: dCDP HMPREF3015_RS01470 trehalose-phosphate pyruvate protocatechuate degradation a 2-methyladenine 2503 GMP adenosylcobamide (5Z,8Z,11Z,14Z,17Z) γ D-ribose 1- a purine base NADH repair L-isoleucine degradation I C-terminal- -(5-phospho- 2251 1D-myo-inositol L-tyrosine GMP HMPREF3015_RS11930 dUTP PRPP HMPREF3015_RS25615 threonylcarbamoyladenine L-methionine degradation L-glutamate degradation II (ortho-cleavage pathway) 5'-deoxyadenosine met -icosapentaenoyl-CoA hexaoxohexadecanoyl- methylguanosine tetradec-5- ethanol nucleoside- synthase (UDP-forming)/ in 23S rRNA 5'-phosphate L-glutamyl)-L-glutamate phosphate 4,5-bisphosphate phosphate GMP adenylate kinase: amidophosphoribosyltransferase: synthase: I (to L-homocysteine) IX (via 4-aminobutanoate) [PKS-acp] in 23S rRNA enoyl-[acp] RS01350 dUTP diphosphatase: diphosphate kinase: trehalose-phosphatase: HMPREF3015_RS11930 HMPREF3015_RS18705 NADH HMPREF3015_RS24600 ile protocatechuate guanylate kinase: ADP HMPREF3015_RS11625 HMPREF3015_RS09045 6 HMPREF3015_RS08055 amidophosphoribosyltransferase: an N -L- HMPREF3015_RS05395 37 branched-chain amino met glu 4-methylphenyl an (S)-2- D-arabinofuranose 4-imidazolone- RS23665 guanylate kinase: nucleoside triphosphate dCTP HMPREF3015_RS10270 α,α-trehalose threonylcarbamoyladenine 2-oxoglutarate adenosylcobinamide- cob(I)alamin- 1-(18-hydroxyoleoyl)- a 3-oxohexacosanoyl- [DNA] RS10625 ADP β acid aminotransferase: methionine ribotide halocarboxylate a malonyl-[acp] 5-phosphate KDO-8P RS03050 HMPREF3015_RS05395 ribonucleotide-diphosphate pyrophosphohydrolase: 5-phospho- - in tRNA glutamate decarboxylase: 3-carboxy-cis GDP [corrinoid ATP sn-glycrol 3-phosphate [acp] 5-propanoate GTP ppGpp HMPREF3015_RS11475 adenosyltransferase: 2-oxoglutarate ferredoxin phosphate haloacid dehalogenase: 3-deoxy-8- DNA polymerase reductase subunit alpha: HMPREF3015_RS11045 D-ribosylamine (S)-3-methyl-2- HMPREF3015_RS05125 adenosylcobinamide- adenosyltranferase] 1-acyl-sn-glycerol-3- 3-deoxy-D-manno- GDP ,cis-muconate oxidoreductase ATP:cob(I)alamin HMPREF3015_RS16135 3-oxoacyl-ACP beta-ketoacyl-[acyl-carrier- phosphooctulonate subunit beta: imidazolonepropionase: ribonucleotide-diphosphate HMPREF3015_RS08805 phosphoribosylamine- oxopentanoate HMPREF3015_RS05720 4-aminobutanoate GDP ribazoletransferase: phosphate acyltransferase: octulosonate 8- RS23570 GDP dUMP (R)-NADHX SAM subunit gamma: adenosyltransferase: HAD family hydrolase: reductase FabG: protein] synthase II: synthase: HMPREF3015_RS21160 HMPREF3015_RS19570 ribonucleotide-diphosphate reductase subunit alpha: ribonucleoside- -glycine ligase: 2-oxoisovalerate HMPREF3015_RS16570 HMPREF3015_RS12190 phosphate phosphatase: HMPREF3015_RS09770 4-methylphenyl-Co adenosylcob(III)HMPREF3015_RS03040 HMPREF3015_RS03915 HMPREF3015_RS11825 HMPREF3015_RS17205 HMPREF3015_RS11240 [+ 2 isozymes] reductase subunit alpha: HMPREF3015_RS08805 diphosphate reductase, thymidylate synthase: HMPREF3015_RS01555 bifunctional ADP-dependent dehydrogenase: a reduced 1-[18-hydroxyoeoyl]-2- a (3R)-3- a 3- N-formimino- HMPREF3015_RS00515 RS14770 nucleoside- ribonucleotide-diphosphate (2-carboxy- GMP β-adenosylcobamide triphosphate alamin-[corrinoid an (R)-2- a nucleoside 5'- RS06195 HMPREF3015_RS08805 ribonucleoside- adenosylcobalamin- HMPREF3015_RS07170 nucleoside- NAD(P)H-hydrate HMPREF3015_RS09820 H + ferredoxin [iron- CO succinyl-CoA a halide anion [18-hydroxy-lioleoyl]-sn hydroxyhexacosanoyl- oxodocosanoyl- KDO-8P L-glutamate Kdo RS24580 2 5'-phosphate hydroxyacid diphosphate kinase: reductase subunit alpha: nucleoside- ribonucleotide-diphosphate GAR diphosphate kinase: 2,5-dihydro- adenosyltranferase] -glycerol 3-phosphate monophosphate diphosphate reductase, dependent: dTMP bifunctional (p)ppGpp dehydratase/NAD(P) sulfur] cluster [acp] [acp] HMPREF3015_RS11625 HMPREF3015_RS08805 diphosphate kinase: reductase subunit alpha: 2-methylbutanoyl-CoA 5-oxofuran- adenosylcobalamin- HMPREF3015_RS16310 phosphoribosylglycinamide HMPREF3015_RS11625 synthetase/guanosine- H-hydrate epimerase: RS14690 ribonucleotide-diphosphate GDP pyrophosphokinase: 2-yl)-acetate ribonucleoside- HMPREF3015_RS11625 HMPREF3015_RS08805 dependent: ATP 3',5'-bis(diphosphate) 3'- (S)-NADHX HMPREF3015_RS10825 SAH reductase subunit alpha: formyltransferase: glycine cleavage DNA with adenine:7,8- a 3- a ribonucleoside 1498 diphosphate reductase, HMPREF3015_RS01470 gamma- a 2-oxo a uracil HMPREF3015_RS08805 ribonucleoside- HMPREF3015_RS16310 dADP HMPREF3015_RS18350 pyrophosphohydrolase: maltopentaose D-glucopyranose [EntB aryl- dihydro-8- a 3-oxotetracosanoyl- (S)-dihydroorotate ATP-dependent NADH- carboxymuconolactone carboxylate cob(II)inamide coenzyme A oxodocosanoyl- 2',3'-cyclic in 16S rRNA his RS16095 GTP adenosylcobalamin- diphosphate reductase, dTDP HMPREF3015_RS01470 adenosylhomocysteinase: a [glycine- 4-alpha-glucanotransferase: ATP carrier protein] [acp] RS17320 hydrate dehydratase: decarboxylase: 2-oxoacid ferredoxin 4'-phosphopantetheinyl oxoguanine mismatchA/G-specific adenine [acp] phosphate 16S rRNA (uracil(1498)- RS10315 dependent: GTP adenosylcobalamin- FGAR (E)-2- HMPREF3015_RS09465 cleavage complex HMPREF3015_RS16305 3-oxoacyl-ACP 3-oxoacyl-ACP dihydroorotase: 2',3'-cyclic-nucleotide dADP anaerobic ribonucleoside- nucleoside- nucleoside- bifunctional (p)ppGpp HMPREF3015_RS10825 HMPREF3015_RS20515 oxidoreductase ATP:cob(I)alamin transferase: glycosylase: N(3))-methyltransferase: histidine ammonia-lyase: HMPREF3015_RS16310 dependent: methylcrotonoyl-CoA H protein] N 6 - glycine dehydrogenase reductase FabG: reductase FabG: HMPREF3015_RS09940 2'-phosphodiesterase: triphosphate reductase: diphosphate kinase: diphosphate kinase: synthetase/guanosine- (4,5-dihydro- subunit beta: 4-alpha-glucanotransferase: adenosyltransferase: HMPREF3015_RS13675 HMPREF3015_RS18665 HMPREF3015_RS11205 HMPREF3015_RS19580 HMPREF3015_RS16310 phosphoribosylformylglycinamidine lipoyl-L-lysine RS05200 anaerobic ribonucleoside- HMPREF3015_RS20595 HMPREF3015_RS11625 HMPREF3015_RS11625 3',5'-bis(diphosphate) 3'- NADH L-homocysteine (aminomethyl-transferring) 5-oxofuran- HMPREF3015_RS15255 HMPREF3015_RS04230 HMPREF3015_RS03040 a holo-[EntB aryl- HMPREF3015_RS11825 HMPREF3015_RS11825 HMPREF3015_RS22350 an N 3 - synthase: HMPREF3015_RS14375 a reduced 3',5'-ADP an apurinic site a (3R)-3- a (3R)-3- triphosphate reductase: : HMPREF3015_RS23630 N-carbamoyl- 1498 pyrophosphohydrolase: gcv system: 2-yl)-acetate triphosphate adenosylcobinamide carrier protein] adenine a ribonucleoside methyluracil urocanate 2+ 2+ nucleoside- anaerobic ribonucleoside- dTTP H + ferredoxin [iron- CO an acyl-CoA maltose maltotetraose within DNA hydroxytetracosanoyl- hydroxydocosanoyl- L-aspartate Co Co HMPREF3015_RS20595 dGDP dATP HMPREF3015_RS23630 2 3'-phosphate RS00680 RS15850 diphosphate kinase: triphosphate reductase: FGAM HMPREF3015_RS25615 (2S,3S)-3-hydroxy-2- in 16S rRNA Mg 2+ Mg 2+ RS01400 GDP Respiration sulfur] cluster [acp] [acp] anaerobic ribonucleoside- superpathway of pyrimidine dGDP HMPREF3015_RS11625 HMPREF3015_RS05470 methylbutanoyl-CoA [+ 2 isozymes] triphosphate reductase: a [glycine- nucleobases salvage phosphoribosylformylglycinamidine superpathway of pyrimidine deoxyribonucleoside salvage a [glycine-cleavage an [L-cysteine (E)-4-hydroxy-3- 38- HMPREF3015_RS05470 nucleoside- nucleoside- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA cleavage complex 6 3-oxoadipate decaprenyl-diphospho-N- UDP-N-acetyl- a long-linear 32 a 3- a uridine guanosine RS23565 cyclo-ligase: HMPREF3015_RS04030 complex H protein] N - α-D-glucopyranose a glucan maltotriose a cytosine 1-cis-vaccenoyl-sn- butanoate 2+ 2+ uracil H protein] N 6 - acetylmuramoyl-pentapeptide α-D-glucosamine α-D-glucan desulfurase]-S- methylbut-2-en- oxodocosanoyl- 2',3'-cyclic DHAP Mg RS19990 Mg diphosphate kinase: diphosphate kinase: aminomethyldihydrolipoyl- in tRNA glycerol-3-phosphate 40 in tRNA uracil dATP 2'-deoxycytidine an [apo BCAA L-serine degradation dihydrolipoyl- undecaprenyldiphospho- 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: sulfanyl-L-cysteine 1-yl diphosphate [acp] RluA family monophosphate methylglyoxal synthase: HMPREF3015_RS11625 HMPREF3015_RS11625 adenine and AIR L-lysine tRNA 2-thiocytidine(32) 1-acyl-sn-glycerol-3- RS10520 phosphoribosyltransferase: dehydrogenase 2-methylacetoacetyl-CoA L-lysine muramoylpentapeptide beta-N- HMPREF3015_RS16305 HMPREF3015_RS16305 4-hydroxy-3-methylbut-2-en- 3-oxoacyl-ACP pseudouridine synthase: 2',3'-cyclic-nucleotide HMPREF3015_RS16290 butyrate kinase: RS07330 adenosine salvage I pyrimidine ribonucleosides salvage I 3-methyl-2-oxobutanoate synthetase TtcA: phosphate acyltransferase: HMPREF3015_RS08290 cytidine deaminase: E2 protein] N 6 acetylglucosaminyltransferase: 1-yl diphosphate synthase: reductase FabG: HMPREF3015_RS12375 2'-phosphodiesterase: HMPREF3015_RS05070 dGTP 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: HMPREF3015_RS12690an [L-cysteine methylglyoxal synthase: Mg 2+ RS07790 Mg 2+ HMPREF3015_RS20040 dehydrogenase 32 HMPREF3015_RS12190 HMPREF3015_RS04960 HMPREF3015_RS22350 UMP cytidine -lipoyl-L-lysine ser HMPREF3015_RS07940 HMPREF3015_RS04230 HMPREF3015_RS04230 a 2-thiocytosine 1-cis-vaccenoyl- HMPREF3015_RS11825 [+ 3 isozymes] HMPREF3015_RS02750 subunit VorB: decaprenyl-pyrophosphoryl- desulfurase]- 2-C-methyl-D- a (3R)-3- 38- butanoyl RS19010 dCMP aminomethyltransferase: in tRNA a pseudouridine dGTP (d)CMP kinase: adenosine 3-methyl-2-oxobutanoate HMPREF3015_RS09760 L-serine ammonia-lyase: UDP (N-acetylglucosamine)-N- a short glucan a short glucan D-glucopyranose a glucan L-cysteine 2-palmitoleoyl-sn- erythritol-2,4- hydroxydocosanoyl- 3'-GMP methylglyoxal phosphate guanine and 2'-deoxyuridine acetyl-CoA HMPREF3015_RS23630 L-threonine degradation II 40 in tRNA HMPREF3015_RS22100 guanine and xanthine and purine-nucleoside cytidine deaminase: (d)CMP kinase: dehydrogenase propanoyl-CoA HMPREF3015_RS00675 glycerol-3-phosphate cyclodiphosphate guanosine salvage 2-oxoisovalerate 2-aminoprop- acetylmuramyl-(pentapeptide) [acp] sulfate phosphorylase: HMPREF3015_RS20040 sulfate RS18815 RS15450 RS22280 UMP kinase: guanosine salvage II xanthosine salvage thymidine kinase: HMPREF3015_RS22100 subunit VorB: dehydrogenase: 2-enoate HMPREF3015_RS15880 HMPREF3015_RS12900 CMP HMPREF3015_RS09760 thr β HMPREF3015_RS15720 dCDP HMPREF3015_RS09820 10 a 5'-half-tRNA a 1-alkyl-sn phenyl-Co - adenosine guanosine adenine uridine an N - maltohexaose maltose a 3'-half-tRNA 1-palmitoyl-sn- a [protein]-L- UDP [+ 3 isozymes] L-glutamate degradation II threonine dehydrogenase: AICAR molecule with a RNA-DNA hybrid -glycerol 3- adenosylcobamide 2',3'-cyclic ser purine-nucleoside guanosine xanthosine thymidine nucleoside- an [apo BCAA an [apo BCAA dehydrogenase formyltetrahydrofolate a 5-formiminotetrahydrofolate glu molecule with glycerol 3-phosphate methionine RS23560 uridine kinase: dUMP L-glutamine HMPREF3015_RS20430 bifunctional 4-alpha-glucanotransferase: a 2',3'-cyclic ribonuclease H: phosphate 5'-phosphate monophosphate phosphorylase: nucleoside- purine-nucleoside adenine diphosphate kinase: dehydrogenase E2 protein] N 6 -S-[2- glutamate a 5'-OH end 1-acyl-sn-glycerol-3- peptide-methionine HMPREF3015_RS10190 degradation I 2-iminopropanoate L-2-amino-3- phosphoribosylaminoimidazolecarboxamide HMPREF3015_RS16305 phosphate end HMPREF3015_RS07655 1-acyl-sn-glycerol-3- alpha-ribazole 2',3'-cyclic-nucleotide thymidine kinase: 6 formimidoyltransferase: 2'-5' RNA ligase: (R)-S-oxide reductase: HMPREF3015_RS12900 diphosphate kinase: phosphorylase: phosphoribosyltransferase: thymidylate synthase: HMPREF3015_RS11625 E2 protein] N - methylpropanoyl]dihydrolipoyl- glu oxobutanoate phosphate acyltransferase: phosphate acyltransferase: phosphatase: 2'-phosphodiesterase: L-serine ammonia-lyase: RS19065 UMP HMPREF3015_RS15720 formyltransferase/IMP cyclohydrolase 4-alpha-glucanotransferase: HMPREF3015_RS04615 ribonuclease HII: RS24865 guanine HMPREF3015_RS11625 HMPREF3015_RS12900 HMPREF3015_RS01710 HMPREF3015_RS07170 dihydrolipoyl-L-lysine L-lysine HMPREF3015_RS19565 HMPREF3015_RS12190 HMPREF3015_RS12190 HMPREF3015_RS04865 HMPREF3015_RS00675 dCTP aspartate transaminase: 2-amino-3-ketobutyrate PurH: HMPREF3015_RS08475 HMPREF3015_RS04230 N-formimino- a ligated tRNA 1-palmitoyl-2- HMPREF3015_RS07780 HMPREF3015_RS16565 HMPREF3015_RS22350 a protein-L- guanine xanthine gln a tetrahydrofolate a 2-acyl-1-alkyl- β UTP HMPREF3015_RS18230 L-glutamate with a 2'-5' linkage a nucleoside 5'- phenyl-Co - methionine- hypoxanthine AMP asparagine CoA ligase: FAICAR a tetrahydrofolate D-glucopyranose maltoheptaose palmitoleoyl-sn- DNA sn-glycerol 3'-AMP pyruvate xanthine CMP phosphorylation Fatty Acid and Lipid Biosynthesis monophosphate adenosylcobamide RS14670 CTP synthase: hypoxanthine synthase asp HMPREF3015_RS17685 glycerol 3-phosphate 3-phosphate (R)-S-oxide phosphoribosyltransferase: phosphoribosyltransferase: pyruvate HMPREF3015_RS22025 phosphoribosyltransferase: adenine and B: asnB glycine C-acetyltransferase: HMPREF3015_RS11925 HMPREF3015_RS21275 CMP dTMP 3-methyl-2-oxobutanoate HMPREF3015_RS11925 adenosine salvage VI palmitate biosynthesis II (bacteria and plants) [+ 5 isozymes] HMPREF3015_RS20435 RS21345 xanthine CTP (d)CMP kinase: palmitoleate biosynthesis I gondoate biosynthesis (anaerobic) dehydrogenase aspartate ammonia-lyase: a plant soluble 1-myristoyl- β-D-glucose RS00930 xanthine glu cob(I)yrinate a,c- D-glucopyranose a (7Z)-hexadec- 1-myristoyl-sn- a ribonucleoside a nucleoside a nucleoside phosphoribosyltransferase: HMPREF3015_RS22100 (from (5Z)-dodec-5-enoate) subunit VorB: HMPREF3015_RS03015 heteroglycan a malonyl-[acp] pimeloyl-CoA ala glycerophosphoglycerol sn-glycerol 6-phosphate XMP gly ATP diamide-[corrinoid 7-enoyl-[acp] glycerol 3-phosphate 5'-monophosphate triphosphate diphosphate HMPREF3015_RS21275 phosphoribosyltransferase: CDP an acetoacetyl-[acp] HMPREF3015_RS09760 4-alpha-glucanotransferase: glycerophosphodiester 3-phosphate adenosine dTDP a malonyl-[acp] fumarate adenosyltranferase] beta-ketoacyl-[acyl-carrier- 8-amino-7- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- nucleoside triphosphate nucleoside- RS05135 HMPREF3015_RS21275 nucleoside- a (5Z)-dodec- an oleoyl-[acp] L-asparagine ATP:cob(I)alamin HMPREF3015_RS16305 phosphodiesterase: 5'-nucleotidase: 2-oxoisovalerate protein] synthase II: oxononanoate synthase: phosphate acyltransferase: pyrophosphohydrolase: diphosphate kinase: GMP adenosine kinase: 3-oxoacyl-ACP 5-enoyl-[acp] beta-ketoacyl-[acyl-carrier- degradation I adenosyltransferase: phosphate acyltransferase: diphosphate kinase: nucleoside- beta-ketoacyl-[acyl-carrier- dehydrogenase: 4-alpha-glucanotransferase: HMPREF3015_RS17205 HMPREF3015_RS04685 HMPREF3015_RS10135 HMPREF3015_RS04825 GMP HMPREF3015_RS09480 protein] synthase II: a (9Z)-3-oxo- HMPREF3015_RS12190 HMPREF3015_RS12190 HMPREF3015_RS11045 HMPREF3015_RS11625 HMPREF3015_RS11625 diphosphate kinase: reductase FabG: protein] synthase II: HMPREF3015_RS09820 HMPREF3015_RS03040adenosyl- HMPREF3015_RS04230 8-amino-7- 1-myristoyl-2- [+ 4 isozymes] 1,2-dimyristoyl- RS15970 RS19885 an (11Z)-3- HMPREF3015_RS17205 a [corrinoid a plant soluble acyl-carrier protein octadec-9- coenzyme A a nucleoside HMPREF3015_RS11625 HMPREF3015_RS11825 a (7Z)-3- HMPREF3015_RS17205 asn triphosphate cobyrinate oxononanoate sn-glycerol a ribonucleoside a nucleoside 5'- Ins(3)P AMP CTP oxo-icos-11- adenosyltransferase] maltose enoyl-[acp] palmitoleoyl-sn- glycerol sn-glycerol a (3R)-3- oxotetradec- asparaginase: L-alanine degradation IV a,c-diamide heteroglycan 3-phosphate monophosphate triphosphate dTTP enoyl-[acp] glycerol 3-phosphate 3-phosphate hydroxybutanoyl- 7-enoyl-[acp] HMPREF3015_RS15470 RS04295 3-oxoacyl-ACP [acp] 3-oxoacyl-ACP Cell Structure Biosynthesis reductase FabG: [+ 2 isozymes] bifunctional UDP-3-O- reductase FabG: asp ala a [formate C a single- a guanine 34 5'-chloro-5'- 1-palmitoyl- an organic HMPREF3015_RS11825 a reduced maltohexaose D-glucopyranose a (3Z)-dec- queuine DNA with lesion a D-hexose RS07515 [3-hydroxymyristoyl] HMPREF3015_RS11825 SAM acetyltransferase]- a malonyl-[acp] stranded RNA sn-glycerol Ins(1)P hydroperoxide RS11390 peptidoglycan biosynthesis I (meso-diaminopimelate containing) a (3R,11Z)-3- alanine dehydrogenase: flavodoxin 3-enoyl-[acp] in tRNA deoxyadenosine N-acetylglucosamine a (3R,7Z)-3- glycine 4-alpha-glucanotransferase: polyribonucleotide tRNA guanosine(34) purine-nucleoside 3-phosphate excinuclease ABC thioredoxin-dependent Carbohydrate Biosynthesis hydroxy-icos- HMPREF3015_RS14215 pyruvate formate lyase- beta-ketoacyl-[acyl-carrier- hexokinase: deacetylase/3-hydroxyacyl- hydroxytetradec- HMPREF3015_RS16305 nucleotidyltransferase: transglycosylase Tgt: phosphorylase: 1-acyl-sn-glycerol-3- inositol monophosphatase: subunit UvrC: thiol peroxidase: α 11-enoyl-[acp] pyruvate activating protein: protein] synthase II: HMPREF3015_RS12785 UDP-N-acetyl- -D-glucosamine 7-enoyl-[acp] 4-alpha-glucanotransferase: HMPREF3015_RS05095 HMPREF3015_RS17600 HMPREF3015_RS12900 phosphate acyltransferase: HMPREF3015_RS09505 HMPREF3015_RS01715 HMPREF3015_RS18825 RS19830 ACP dehydratase: (3R,11Z)-3-hydroxy-icos-11- HMPREF3015_RS02460a [formate C HMPREF3015_RS17205a (5Z)-3- UDP-N-acetylglucosamine gluconeogenesis I 3-hydroxy cis ∆ 7 a flavodoxin HMPREF3015_RS04230 a nucleoside a single- 5-chloro-5- HMPREF3015_RS12190 PRPP biosynthesis HMPREF3015_RS04005 enoyl-[acp] dehydratase: met 5'-deoxyadenosine acetyltransferase]- acyl-carrier protein oxododec- a queuosine 34 1-palmitoyl-2- [+ 2 isozymes] [+ 2 isozymes] D-hexose 6- 1-carboxyvinyltransferase: GDP-L-fucose biosynthesis -tetradecenoyl- semiquinone diphosphate stranded RNA guanine adenine deoxyribose myo-inositol DNA without HMPREF3015_RS04005 glycin -2-yl radical maltose maltopentaose 5-enoyl-[acp] in tRNA cis-vaccenoyl an alcohol phosphate RS15770 I (from GDP-D-mannose) a (2E)-but- [acp] dehydratase: 1-phosphate lesion RS04350 HMPREF3015_RS05415 (S)-malate D-ribose 5- phosphatidate GDP-α-D- 2-enoyl-[acp] HMPREF3015_RS04005 a (2E,11Z)-icosa- UDP-N-acetyl-α-D-glucosamine-enolpyruvate phosphate ribose-phosphate a (2E,7Z)- 2,11-dienoyl-[acp] Carboxylate Degradation mannoseGDP-mannose RS13625 UDP-N-acetylmuramate pyrophosphokinase: tetradeca-2,7- a 1-phosphatidyl- 1-palmitoyl- malate dehydrogenase, 1-stearoyl-sn- a maltodextrin D-glucopyranose a (4Z)-hexadec- a [ThiI sulfur-carrier 5'-deoxy-5'- 2-deoxy-D-ribose (2R,3S)-3- acrylamide malate dehydrogenase: 4,6-dehydratase: HMPREF3015_RS18020 dienoyl-[acp] phosphatidylethanolamine a malonyl-[acp] cys sn-glycerol Ins(2)P dehydrogenase: superpathway of β-D- a palmitoyl-[acp] fluoroadenosine 1D-myo-inositol isopropylmalate malate dehydrogenase: NAD-requiring: HMPREF3015_RS22655 biosynthesis I glycerol 3-phosphate 4-alpha-glucanotransferase: 4-enoyl-[acp] protein]-L-cysteine purine-nucleoside 3-phosphate ribokinase: RS10710 HMPREF3015_RS20420 HMPREF3015_RS06970 GDP-4-dehydro- PRPP D-galacturonate degradation I pyruvate fermentation to acetate IV 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- 3-isopropylmalate RS08110 ala HMPREF3015_RS11535 HMPREF3015_RS06970 a butanoyl-[acp] glucuronosides degradation cysteine desulfurase: phosphorylase: phosphatidylinositol kinase: 1-acyl-sn-glycerol-3- HMPREF3015_RS15440 amidase: glu α-D-rhamnose phosphate acyltransferase: HMPREF3015_RS16305 protein] synthase II: inositol monophosphatase: dehydratase: UDP-N-acetyl-α-D-muramate a gondoyl-[acp] HMPREF3015_RS07755 HMPREF3015_RS06990 phosphate acyltransferase: HMPREF3015_RS03460 a CDP-diacylglycerol a β-D-glucuronoside aldehydo-D- HMPREF3015_RS12190 4-alpha-glucanotransferase: HMPREF3015_RS17205 a [ThiI sulfur- HMPREF3015_RS12900 HMPREF3015_RS09505 ribokinase: HMPREF3015_RS19640 a sugar RS18070 a sugar beta-ketoacyl-[acyl-carrier- pyruvate a (6Z)-3- 5-fluoro-5- HMPREF3015_RS12190 a (7Z)-tetradec- galacturonate 1-stearoyl-2-palmitoyl- HMPREF3015_RS04230 carrier protein]-S- ala a 1-phosphatidyl- 1-palmitoyl- HMPREF3015_RS03125 HMPREF3015_RS19645 glutamate racemase: UDP-N-acetylmuramate- pyruvate protein] synthase II: beta-glucuronidase: glucuronate isomerase: acyl-carrier protein acyl-carrier protein oxooctadec- 2-deoxy-D-ribose 7-enoyl-[acp] sn-glycerol 3-phosphate maltose a maltodextrin sulfanyl-L-cysteine deoxy-D-ribose adenine 1D-myo-inositol myo-inositol (2S)-2- acrylate HMPREF3015_RS07435 oxaloacetate HMPREF3015_RS17205 HMPREF3015_RS04385 HMPREF3015_RS17540 6-enoyl-[acp] 2-myristoyl -L-alanine ligase: GDP-β-L-fucose a 3-sn-phosphatidyl- formate C- 1-phosphate 4-phosphate 5-phosphate isopropylmalate beta-ketoacyl-[acyl-carrier- D-glucopyranuronate D-tagaturonate phosphatidate 2+ 2+ HMPREF3015_RS07935 L-serine RS08100 RS24085 Mo RS18415 Mo phosphoenolpyruvate a 3-oxohexanoyl- protein] synthase II: acetyltransferase: D-glt phosphatidylserine phosphoenolpyruvate synthase/pyruvate [acp] HMPREF3015_RS17205 tagaturonate reductase: HMPREF3015_RS02455 UDP-N-acetyl-α-D-muramoyl-L-alanine (R)-2- carboxykinase (ATP): phosphate dikinase: a (9Z)-3- decarboxylase: N-acetyl-4-O- an insertion sequence Kdo CTP lipid IV biosynthesis 3-oxoacyl-ACP HMPREF3015_RS17550 1-stearoyl-sn- maltotetraose D-glucopyranose a (5Z)-tetradec- 3'-dephospho- phosphoenol maltose hydroxyglutaryl- acetamide A HMPREF3015_RS15935 a stearoyl-[acp] a malonyl-[acp] element IS30 HMPREF3015_RS08295 HMPREF3015_RS07015 reductase FabG: oxohexadec- glycerol 3-phosphate 5-enoyl-[acp] acetylneuraminate ATP dADP iodide RS03470 iodide UDP-N-acetylmuramoyl-L- aldehydo-D-glucuronate D-altronate acetyl-CoA formate 4-alpha-glucanotransferase: sialate O-acetylesterase: CoA pyruvate 3-deoxy-manno- maltose O- CoA a (3R)-3- 9-enoyl-[acp] an L-1- 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- transposase: alanine--D-glutamate ligase: HMPREF3015_RS11825 HMPREF3015_RS16305 HMPREF3015_RS01170 dephospho-CoA kinase: pyruvate kinase: octulosonate acetyltransferase: 2-hydroxyglutaryl- amidase: UDP-N-acetyl- phosphoenol 3-oxoacyl-ACP phosphatidylethanolamine phosphate phosphate acyltransferase: protein] synthase II: HMPREF3015_RS19215 RS24690 hydroxytetradecanoyl- α a (3R)-3- glucuronate isomerase: altronate dehydratase: cytidylyltransferase: CoA dehydratase: HMPREF3015_RS03460 RS20765 HMPREF3015_RS07950 -D-glucosamine pyruvate reductase FabG: HMPREF3015_RS12190 4-alpha-glucanotransferase: HMPREF3015_RS17205 [+ 2 isozymes] HMPREF3015_RS18765 [+ 12 isozymes] HMPREF3015_RS15150 HMPREF3015_RS26460 [acp] UDP-N-acetylglucosamine hydroxyhexanoyl- HMPREF3015_RS17540 HMPREF3015_RS06155 acetyltransferase: a (7Z)-3-oxo- α HMPREF3015_RS20535 HMPREF3015_RS11825 1-stearoyl-2-stearoyl-sn HMPREF3015_RS04230 acetate N-acetylneuraminate an insertion HMPREF3015_RS18035 6-O-acetyl- -D- an anion RS05890 an anion α acyltransferase: phosphopyruvate [acp] HMPREF3015_RS07235 acyl-carrier protein acyl-carrier protein hexadec-7- ADP H + pyruvate (E)-glutaconyl- meso-diaminopimelate UDP-N-acetyl- -D-muramoyl- O-antigen building blocks biosynthesis (E. coli) a (3R,9Z)-3- 2-dehydro- -glycerol 3-phosphate coenzyme A sequence IS30 with dATP CMP-Kdo glucopyranosyl- acetate UDP-3-O-[(3R)-3- hydratase: D-fructuronate maltose maltotriose enoyl-[acp] L-alanyl-D-glutamate HMPREF3015_RS04000 bifunctional UDP-3-O- 3-deoxy-D- (1->4)-D-glucose CoA UDP-α-D- α hydroxyhexadec- acetyl phosphate integrated transposon hydroxymyristoyl]-N- HMPREF3015_RS12740 -D- D-glucopyranose [3-hydroxymyristoyl] long-chain fatty gluconate α galactose 9-enoyl-[acp] D-ala UDP-N-acetylmuramoyl-L- acetyl- -D-glucosamine 2-phospho- glucopyranose 6-phosphate N-acetylglucosamine 9 RS18370 fluoride RS12750 fluoride glucose-6-phosphate 3-hydroxy cis ∆ acid activation 2-dehydro-3- RS25765 alanyl-D-glutamate--2, 6- bifunctional UDP-3-O- D-glycerate 1-phosphate deacetylase/3-hydroxyacyl- acetate kinase: 1-stearoyl- N-acetyl-9-O- glucose-1-phosphate isomerase: -hexadecenoyl- deoxygluconokinase: 1-cis-vaccenoyl-sn- a (3Z)-dodec- a 1-acyl-sn-glycerol CMP-Kdo lipid IV a uridine in tRNA α-D-ribofuranose roseoflavin (S)-malate diaminopimelate ligase: [3-hydroxymyristoyl] ACP dehydratase: a long-chain HMPREF3015_RS07240 a palmitoleoyl-[acp] an oleoyl-[acp] sn-glycerol a malonyl-[acp] acetylneuraminate A phosphoenol D-alanine--D-alanine ligase: cofactor-independent UDP-Galf thymidylyltransferase: [acp] dehydratase: D-mannonate HMPREF3015_RS06165 glycerol-3-phosphate 3-enoyl-[acp] 3-phosphate dGDP N-acetylglucosamine HMPREF3015_RS16410 fatty acid 3-phosphate sialate O-acetylesterase: 3-deoxy-D-manno- pyruvate ribokinase: HMPREF3015_RS07380 HMPREF3015_RS07960 phosphoglycerate mutase: HMPREF3015_RS05370 HMPREF3015_RS04005 long-chain-fatty- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- tRNA dihydrouridine bifunctional riboflavin dTDP-α-D-glucose F6P HMPREF3015_RS04005 mannonate dehydratase: acetate HMPREF3015_RS01170 1-acyl-sn-glycerol-3- octulosonic acid HMPREF3015_RS15440 fumarate hydratase: a purine RS12240 a purine deacetylase/3-hydroxyacyl- a (2E,9Z)- acid--CoA ligase: KDGP phosphate acyltransferase: phosphate acyltransferase: protein] synthase II: pyruvate kinase: synthase DusB: kinase/FAD synthetase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- HMPREF3015_RS15480 a (2E)-hex- phosphate acyltransferase: transferase: HMPREF3015_RS15800 D-alanyl-D-alanine ACP dehydratase: dTDP-glucose glutamine--fructose-6- HMPREF3015_RS16270 HMPREF3015_RS02340 HMPREF3015_RS12190 HMPREF3015_RS12190 HMPREF3015_RS17205 [+ 2 isozymes] HMPREF3015_RS15150 HMPREF3015_RS08940 ribokinase: HMPREF3015_RS05035 γ 2,3-bisphosphoglycerate- 2-enoyl-[acp] hexadeca-2,9- 1-cis-vaccenoyl- 1-stearoyl-2- a (5Z)-3-oxo- HMPREF3015_RS12190 RS25710 -D-glutamyl-meso-2,6-diaminopimelate HMPREF3015_RS04005 mannonate dehydratase: bifunctional 4-hydroxy- acetate N-acetylneuraminate HMPREF3015_RS19270 HMPREF3015_RS03125 RS14230 independent 4,6-dehydratase: phosphate transaminase dienoyl-[acp] [+ 3 isozymes] acyl-carrier protein 2-palmitoleoyl-sn- acyl-carrier protein oleoyl-sn-glycerol acyl-carrier protein tetradec-5- a 1-acyl-2-palmitoyl-sn α-Kdo-(2->6) dGTP pyruvate a 5,6-dihydrouridine α roseoflavin UDP-3-O-(3- a long-chain HMPREF3015_RS20835 CMP -D-ribose fumarate 2+ 2+ HMPREF3015_RS05375 (isomerizing): 2-oxoglutarate aldolase/ glycerol-3-phosphate 3-phosphate enoyl-[acp] -lipid IV in tRNA 5'-phosphate Zn RS01575 Zn bifunctional UDP-N- hydroxymyristoyl) phosphoglycerate mutase: fatty acyl-CoA -glycerol 3-phosphate A 5-phosphate HMPREF3015_RS10265 2-dehydro-3- 2-dehydro-3-deoxy- acetylmuramoyl-tripeptide:D- -α-D-glucosamine HMPREF3015_RS07800 dTDP-4-dehydro- 6-deoxy-α-D- D-glucosamine deoxy-D-gluconate phosphogluconate alanyl-D-alanine ligase/ UDP-3-O-(3- 3-phospho- superpathway of acetate utilization and formation glucopyranose 6-phosphate a hexanoyl-[acp] 2-dehydro-3- aldolase: a (2'R)-2'- 1402 asp asp alanine racemase: hydroxymyristoyl) D-glycerate a palmitoleoyl-[acp] a glutaryl-[acp] a 1-phosphatidyl- a uracil in DNA L-threo-3- a cytidine a [protein]-L- F6P phosphatidylglycerophosphate HMPREF3015_RS06170 a palmitoleoyl-[acp] 1-myristoyl-sn- a malonyl-[acp] a pimeloyl-[acp] ala hydroxy- N5-CAIR RS11120 HMPREF3015_RS14685 glucosamine N- dTDP-4-dehydrorhamnose phosphoglucosamine deoxygluconokinase: 1D-myo-inositol in 16S rRNA proline (ω = 180) (1-octadecenoyl(9Z), 2-palmitoyl) RS01125 RS18225 phosphoglycerate kinase: D-glyceraldehyde glycerol 3-phosphate methyl ester phytoceramide uracil-DNA glycosylase: phenylserine acyltransferase: 3,5-epimerase: mutase: beta-ketoacyl-[acyl-carrier- HMPREF3015_RS06165 acetate 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- 8-amino-7- low specificity L- 16S rRNA (cytidine(1402) peptidylprolyl isomerase: diphosphate--fructose- ala ala UDP-N-acetylmuramoyl- HMPREF3015_RS00485 acyl-ACP thioesterase: 3-phosphate acetyl-CoA synthetase: HMPREF3015_RS16370 HMPREF3015_RS04010 HMPREF3015_RS17565 HMPREF3015_RS11890 protein] synthase II: phosphate acyltransferase: protein] synthase II: oxononanoate synthase: threonine aldolase: -2'-O)-methyltransferase: HMPREF3015_RS02125 6-phosphate 1- tripeptide--D-alanyl- HMPREF3015_RS22180 KDGP HMPREF3015_RS01050 UDP-2-N,3-O-bis[(3R)- dTDP-4-dehydro- D-glucosamine HMPREF3015_RS17205 acetate kinase: HMPREF3015_RS12190 HMPREF3015_RS17205 HMPREF3015_RS04685 a very-long-chain uracil-DNA glycosylase: HMPREF3015_RS01845 phosphotransferase: RS05755 1-myristoyl-2- a 1,2-diacyl- HMPREF3015_RS15730 [+ 7 isozymes] D- alanine ligase: 13-DPG β-L-rhamnose HMPREF3015_RS07240 a 3-oxopimeloyl- 8-amino-7- inositol phospho-(2'R)- HMPREF3015_RS13495 a 2'-O- HMPREF3015_RS09845 3-hydroxytetradecanoyl]- 1-phosphate a 3-oxooctanoyl- palmitoleate acyl-carrier protein palmitoleoyl-sn- acyl-carrier protein acyl-carrier protein sn-glycerol gly benzaldehyde a [protein]-L- β-D-fructose 1,6- 1-oleoyl-2-palmitoyl- HMPREF3015_RS03560 bifunctional 4-hydroxy- [acp] methyl ester oxononanoate 2'-hydroxyphytoceramide an apyrimidinic methylcytidine 1402 CAIR α-D-glucosamine dTDP-4-dehydrorhamnose [acp] glycerol 3-phosphate uracil proline (ω = 0) phosphatidylglycerol RS15435 glyceraldehyde-3- 2-oxoglutarate aldolase/ site in DNA bisphosphate RS16180 α UDP-2,3-diacylglucosamine reductase: acetyl phosphate acetyl-CoA in 16S rRNA UDP-N-acetyl- -D-muramoyl-L- triose-phosphate phosphate dehydrogenase: 3-oxoacyl-ACP 2-dehydro-3-deoxy- γ diphosphatase: HMPREF3015_RS14390 phosphatidylglycerol alanyl- -D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate isomerase: HMPREF3015_RS04200 N-acetyl-α-D- reductase FabG: phosphogluconate HMPREF3015_RS07305 dTDP-β-L- (1S,2R)-1- α diaminopimeloyl-D-alanyl-D-alanine HMPREF3015_RS11645 glucosamine HMPREF3015_RS11825 biosynthesis II (non-plastidic) 4-methyl-2- a [release factor]- an (1,5)- α-ribazole D-ribulose RS19840 D-glyceraldehyde rhamnose aldolase: 1-palmitoyl-sn- a malonyl-[acp] isobutanoate a DNA segment DHAP 1-phosphate a (3R)-3- phosphate a palmitoleoyl-[acp] a malonyl-[acp] oxopentanoate C-(indol-3- thr L-glutamine L-arabinan 5-phosphate lipid X 3-phosphate HMPREF3015_RS06170 glycerol 3-phosphate methyl ester ser alpha-N- 5'-phosphate hydroxyoctanoyl- DHAP acetyltransferase: 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- acetyl-CoA synthetase: 2-oxoisovalerate yl)glycerol low specificity L- peptide chain release recombinase: ribulose-phosphate RS10160 D-glyceraldehyde tryptophan synthase arabinofuranosidase: alpha-ribazole RS16535 lipid-A-disaccharide [acp] NAD(P)H-dependent pyruvate HMPREF3015_RS07235 phosphate acyltransferase: protein] synthase II: HMPREF3015_RS01050 dehydrogenase: 3-phosphate threonine aldolase: factor N(5)-glutamine HMPREF3015_RS20220 3-epimerase: 3-phosphate subunit beta: HMPREF3015_RS18405 phosphatase: undecaprenyldiphospho-N-acetylmuramoyl- synthase: bifunctional UDP-3-O- glycerol-3-phosphate HMPREF3015_RS12190 HMPREF3015_RS17205 HMPREF3015_RS09820 HMPREF3015_RS01845 methyltransferase: [+ 7 isozymes] HMPREF3015_RS11870 UDP-N-acetyl- 1-palmitoyl-2- HMPREF3015_RS06695 HMPREF3015_RS16565 L-alanyl-γ-D-glutamyl-meso-2,6- HMPREF3015_RS01500 fructose-bisphosphate [3-hydroxymyristoyl] dehydrogenase: a 3-oxoglutaryl- isobutanoyl-CoA AMP diphosphate NADH CO isovaleryl-CoA D-glyceraldehyde HMPREF3015_RS07470 a DNA segment in [+ 4 isozymes] D-xylulose α-D-glucosamine acyl-carrier protein palmitoleoyl-sn- acyl-carrier protein 2 gly acetaldehyde a [release factor]-N 5 α-L- α diaminopimeloyl-D-alanyl-D-alanine aldolase: N-acetylglucosamine HMPREF3015_RS16415 [acp] methyl ester 3-phosphate trp -ribazole 5-phosphate RS25320 lipid A disaccharide sn-glycerol glycerol 3-phosphate -methyl-L-glutamine reverse orientation arabinofuranose undecaprenyldiphospho- HMPREF3015_RS18455 deacetylase/3-hydroxyacyl- UDP-α-D-galactose biosynthesis 3-phosphate RS03120 muramoylpentapeptide beta-N- tetraacyldisaccharide [+ 2 isozymes] ACP dehydratase: RS24235 4'-kinase: Fatty Acid and Lipid Degradation acetylglucosaminyltransferase: HMPREF3015_RS04005 1-stearoyl- 1939 a monocarboxylic a 2,3,4-saturated UDP-α-D-glucose a 2,3,4-saturated a 2,3,4-saturated 2- an acyl-[acyl- maltoheptaose 1-cis-vaccenoyl-sn- a uracil L-iditol HMPREF3015_RS07940 HMPREF3015_RS12895 sn-glycerol isovalerate L-allo-threonine 1,2-diacyl-sn UDP-N-acetyl-D- a (2E)-oct- fatty acyl-[acp] lysophosphatidate carrier protein] glycerol-3-phosphate in 23S rRNA acid amide biotin ATP CTP UDP-glucose 4- a 1-acyl-sn fatty acid β-oxidation I 3-phosphate acetyl-CoA synthetase: alpha-glucosidase: 23S rRNA sorbitol dehydrogenase: -glycerol 3- RS11175 lipid IV β-D-fructose 1,6- galactosamine biosynthesis I 2-enoyl-[acp] 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- low specificity L- lipid II (meso diaminopimelate containing) A HMPREF3015_RS02325 epimerase GalE: -glycerol 3- phosphate acyltransferase: phosphate acyltransferase: HMPREF3015_RS01050 threonine aldolase: (uracil(1939)-C(5))- amidase: HMPREF3015_RS12130 biotin--[acetyl-CoA- phosphate bisphosphate UDP-N-acetyl- phosphate acyltransferase: HMPREF3015_RS21845 phosphate a (3Z)-alk-3- HMPREF3015_RS12190 HMPREF3015_RS12190 [+ 8 isozymes] HMPREF3015_RS01845 methyltransferase RlmD: HMPREF3015_RS03460 sorbitol dehydrogenase: carboxylase] ligase: RS12235 fructose-bisphosphatase α-D-glucosamine a 2,3,4-saturated a 1-stearoyl 2- HMPREF3015_RS12190 a CDP-2,3,4- RS08360 UDP-glucose 4-epimerase: UDP-N-acetylglucosamine 1-acyl-sn-glycerol-3- enoyl-CoA isovaleryl-CoA AMP diphosphate D-glucopyranose maltohexaose HMPREF3015_RS25365 HMPREF3015_RS03270 HMPREF3015_RS15900 acetaldehyde gly 1939 biotinyl-5'- saturated- class III: acyl-carrier protein 1,2-diacyl-sn- acyl-carrier protein acyl-sn-glycerol 1,2-dicis-vaccenoyl- a 5-methyluracil a monocarboxylate HMPREF3015_RS20430 4-epimerase: phosphate acyltransferase: keto-L-sorbose adenylate diacylglycerol HMPREF3015_RS22635 UDP-α-D-galactose glycerol 3-phosphate 3-phosphate phosphatidate in 23S rRNA HMPREF3015_RS24010 an octanoyl-[acp] HMPREF3015_RS12190 UDP-N-acetyl-α- a 1,2-diacyl- long-chain-fatty- RS22095 F6P a 2,3,4-saturated D-galactosamine sn-glycerol coenzyme A acid--CoA ligase: a (2E)-2- beta-ketoacyl-[acyl-carrier- fatty acid a [protein]- a damaged an XLLG RS10960 glucose-6-phosphate 3-phosphate HMPREF3015_RS16270 enoyl-CoA an acyl-[acyl- a [protein]-L-lysine maltopentaose an α-limit dextrin 2-hydroxyisobutyramide meso- a cytosine in DNA citrate GDP-β-L-fucose RS03815 protein] synthase II: a palmitoyl-[acp] a malonyl-[acp] a malonyl-[acp] L-glutamine DNA pyrimidine xylogulcan isomerase: [+ 3 isozymes] carrier protein] alpha-glucosidase: 4-alpha-glucanotransferase: diaminopimelate HMPREF3015_RS17205 acyl-CoA dehydrogenase: a 2,3,4- beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- transglutaminase domain- DNA methylase: HMPREF3015_RS16410 containing protein: HMPREF3015_RS02325 HMPREF3015_RS16305 amidase: diaminopimelate aconitate hydratase: DNA glycosylase: a 3-oxodecanoyl- HMPREF3015_RS01890 saturated (3R)-3- protein] synthase II: protein] synthase II: HMPREF3015_RS16865 D-glucopyranose a 2,3,4- HMPREF3015_RS12025 [+ 8 isozymes] 4-alpha-glucanotransferase: HMPREF3015_RS03460 dehydrogenase: HMPREF3015_RS22160 HMPREF3015_RS12220 RS12395 [acp] a CDP- hydroxyacyl-CoA HMPREF3015_RS17205 HMPREF3015_RS17205 a protein with an [+ 4 isozymes] an XLFG 6-phosphate a 2,3,4-saturated saturated (3S)-3- HMPREF3015_RS07070 GDP diacylglycerol a 3-oxooctadecanoyl- 6 γ D-glucopyranose maltotetraose HMPREF3015_RS04230 3-oxoacyl-ACP fatty acyl CoA acyl-carrier protein acyl-carrier protein a 3-oxoacyl-[acp] N -( -glutamyl)- a α-limit dextrin 2-hydroxy-2- (S)-2,3,4,5- a 5-methylcytosine an apyrimidinic xylogulcan hydroxyacyl-CoA [acp] D-threo-isocitrate RS02375 RS25890 reductase FabG: L-lysine crosslink with short branches methylpropanoate tetrahydrodipicolinate in DNA site in DNA HMPREF3015_RS11825 a (3R)-3- 1-(3-sn- Amino Acid Biosynthesis 1-myristoyl- all-trans- 1-oleoyl-sn RS25330 hydroxydecanoyl- phosphatidyl) fatty acid elongation -- saturated Secondary Metabolite Degradation a 2,3,4-saturated a 2,3,4-saturated 2-carboxy-1,4- (R)-methylmalonyl- a negatively (3Z)-hex- α dodecaprenyl [DNA] 4-guanidinobutyramide -glycerol 3- -amylose [acp] -sn-glycerol fatty acyl CoA 3-oxoacyl-CoA an acetyl-[acp] a malonyl-[acp] a myristoyl-[acp] sn-glycerol naphthoquinol 4'-phosphopantetheine ATP CoA supercoiled DNA 3-en-1-ol 3-phosphate diphosphate exodeoxyribonuclease III: phosphate 1,4-alpha-glucan- RS18435 L-histidine biosynthesis bifunctional UDP-3-O- 3-phosphate beta-ketoacyl-[acyl-carrier- 1-acyl-sn-glycerol-3- 1,4-dihydroxy-2-naphthoate methylmalonyl- topoisomerase: CHAT domain- RS09580 L-tryptophan biosynthesis L-isoleucine biosynthesis IV L-alanine biosynthesis I L-threonine biosynthesis anhydromuropeptides recycling I HMPREF3015_RS25295 pantetheine-phosphate amidase: 1-acyl-sn-glycerol-3- superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis I (via L-ornithine) L-lysine biosynthesis III [3-hydroxymyristoyl] an acetoacetyl-[acp] protein] synthase II: phosphate acyltransferase: polyprenyltransferase: CoA epimerase: HMPREF3015_RS23220 containing protein: branching protein: a 2'- adenylyltransferase: HMPREF3015_RS03460 phosphate acyltransferase: N-acetylglucosamine HMPREF3015_RS17205 HMPREF3015_RS12190 HMPREF3015_RS05380 HMPREF3015_RS00560 [+ 2 isozymes] HMPREF3015_RS09300 HMPREF3015_RS05675 PRPP 3-methyl-2- GlcNAc-1,6- 1,2-dimyristoyl- deoxyribonucleoside [DNA] HMPREF3015_RS25820 HMPREF3015_RS12190 pyruvate gln chorismate propanoate L-homoserine deacetylase/3-hydroxyacyl- anhMurNAc- an acetoacetyl-[acp] acyl-carrier protein acyl-carrier protein sn-glycerol DMK-12 5'-monophosphate 3'-dephospho- dioleoyl (S)-methylmalonyl- (3Z)-hex-3- amylopectin RS12310 thr glu asp oxobutanoatebranched-chain amino an L-1- 4-guanidinobutanoate a relaxed DNA ATP long-chain fatty ACP dehydratase: L-Ala-γ-D-Glu- acetyl-CoA 3-phosphate CoA phosphatidate CoA en-1-yl acetate bifunctional aspartate acid aminotransferase: phosphatidyl- phosphoribosyltransferase: acetolactate synthase: acid--CoA ligase: HMPREF3015_RS04005 DAP-D-Ala kinase/homoserine anthranilate synthase: sn-glycerol RS10460 RS00360 HMPREF3015_RS10110 HMPREF3015_RS22185 HMPREF3015_RS21750 HMPREF3015_RS11475 HMPREF3015_RS06690 O-phospho- a (2E)-dec- a 3-oxoacyl-[acp] HMPREF3015_RS22190 dehydrogenase I: val 1-palmitoyl- an all-trans- a (1->4)- 4-methylphenyl-Co 1-(5-phospho- [+ 3 isozymes] L-homoserine 3-oxoacyl-ACP a cis- 2-carboxy-1,4- a single a double 4-imidazolone- a peptide with a HMPREF3015_RS15475 2-enoyl-[acp] C1 Compound Utilization and Assimilation phenylacetate sn-glycerol polyisoprenyl α-D-glucan palmitoleoyl-CoA β-adenosylcobamide L-saccharopine β (2Z)-2-aminobut- anthranilate propanoyl-CoA reductase FabG: vaccenoyl-[acp] stranded DNA stranded DNA 5-propanoate leader sequence -D-ribosyl)-ATP (S)-2-acetolactate N-acetyl-L- [+ 2 isozymes] diphosphate naphthoquinol alpha-glucosidase: 5'-phosphate RS14695 2-enoate threonine synthase: HMPREF3015_RS11825 N-acetyl-β-D- L-alanyl-γ-D- phenylacetate--CoA ligase: 3-phosphate1-acyl-sn-glycerol-3- 1,4-dihydroxy-2-naphthoate saccharopine phosphoribosyl-ATP glutamate L-aspartyl- 2-oxoacid ferredoxin beta-ketoacyl-[acyl-carrier- HMPREF3015_RS02325 deoxyribonuclease IV: acyl-CoA dehydrogenase: alpha-ribazole DNA gyrase subunit A: urocanate hydratase: ketol-acid anthranilate HMPREF3015_RS15485 glucosamine-1,6- glutamyl-meso-2,6- formaldehyde oxidation HMPREF3015_RS21280 phosphate acyltransferase: polyprenyltransferase: dehydrogenase: pyrophosphatase: 4-phosphate protein] synthase II: formate assimilation into 5,10- [+ 8 isozymes] HMPREF3015_RS19020 HMPREF3015_RS01890 phosphatase: HMPREF3015_RS24505 HMPREF3015_RS19560 phosphoribosyltransferase: oxidoreductase VII (THF pathway) HMPREF3015_RS12190 RS19170 reductoisomerase: acetylglutamate kinase: L-lysine biosynthesis VI HMPREF3015_RS17205 anhydro-N-acetyl- diaminopimeloyl- methylenetetrahydrofolate 1-palmitoyl-2- HMPREF3015_RS05380 a (1->4)- HMPREF3015_RS16565 HMPREF3015_RS18830 RS20870 HMPREF3015_RS20470 HMPREF3015_RS06680 subunit beta: diphosphate AMP phenylacetyl-CoA D-glucopyranose a leader sequence a peptide HMPREF3015_RS22175 HMPREF3015_RS07690 aspartate-semialdehyde ala thr β-D-muramate D-alanine acyl-carrier protein cis-vaccenoyl DMKH α (2E,9Z)- allysine glu a negatively β a decanoyl-[acp] 2 -D-glucan 4-methylphenyl-Co urocanate 1-(5-phospho- - dehydrogenase: HMPREF3015_RS15255 formaldehyde a 5'-phosphooligonucleotide (2R)-2,3- 2-iminobutanoate N-(5-phosphoribosyl) a (3R)-3- beta-hexosaminidase: formate phosphatidate hexadecenoyl-CoA β-adenosylcobamide supercoiled DNA D-ribosyl)-AMP N-acetylglutamyl- HMPREF3015_RS03525 a 2,3,4-saturated dihydroxy-3- asp -anthranilate 2-oxobutanoate bifunctional UDP- beta-ketoacyl-[acyl-carrier- hydroxyacyl-[acyl- HMPREF3015_RS18525 formate-- RS16065 bifunctional phosphoribosyl- phosphate fatty acyl-[acp] methylbutanoate bifunctional aspartate L-aspartate- phosphoribosylanthranilate N-acetylmuramoyl- protein] synthase II: carrier protein]bifunctional UDP-3-O- [+ 6 isozymes] L-alanyl-γ-D- tetrahydrofolate ligase: AMP cyclohydrolase/ a 5,10- 2,3-dihydroxy- N-acetyl-gamma-glutamyl- kinase/homoserine semialdehyde isomerase: acetolactate synthase: tripeptide:D-alanyl- HMPREF3015_RS17205 [3-hydroxymyristoyl] a single 1-palmitoyl- all-trans- (7Z)- (indol-3-yl) (R)-propane- an organic a (1->4)- 1,6-anhydro-N- glutamyl-meso- 10 HMPREF3015_RS18220 2-carboxy-1,4- RS01920 RS00195 phosphoribosyl-ATP phosphate reductase: HMPREF3015_RS22185 methylenetetrahydrofolate an N - a palmitoyl-[acp] sn-glycerol tridecaprenyl a tripeptide butanoyl-CoA phosphate roseoflavin α-D-glucan isovalerate dehydratase: dehydrogenase I: HMPREF3015_RS06670 D-alanine ligase/ L-glutamate biosynthesis III a 3- N-acetylglucosamine acetyl-β-muramate diaminopimelate stranded DNA naphthoquinol hexadecenoyl-CoA ATP acetamide 1,2-diol hydroperoxide diphosphatase HisIE: 4-hydroxy- formyltetrahydrofolate exodeoxyribonuclease VII: 5'-phosphate HMPREF3015_RS22195 2-oxobutanoate HMPREF3015_RS01070 HMPREF3015_RS15475 1-(o- HMPREF3015_RS22190 alanine racemase: oxododecanoyl- deacetylase/3-hydroxyacyl- bifunctional 3-phosphate1-acyl-sn-glycerol-3- diphosphate 1,4-dihydroxy-2-naphthoate peptidase T: phosphate alkyl hydroperoxide 1,4-alpha-glucan- HMPREF3015_RS20470 N-acetyl-L- tetrahydrodipicolinate methylenetetrahydrofolate HMPREF3015_RS11465 HMPREF3015_RS18710 acyl-CoA dehydrogenase: bifunctional riboflavin amidase: lactaldehyde reductase: branching protein: 3-methyl-2- [+ 2 isozymes] carboxyphenylamino) (S)-2-aceto-2- HMPREF3015_RS14685 [acp] ACP dehydratase: bifunctional phosphate acyltransferase: polyprenyltransferase: butyryltransferase: reductase subunit F: 1-(5-phospho-β-D-ribosyl)- acetolactate synthase: glutamate 5- L-aspartyl- synthase: 2-oxoglutarate dehydrogenase/ HMPREF3015_RS11470 a proteinogenic HMPREF3015_RS01890 kinase/FAD synthetase: HMPREF3015_RS03460 HMPREF3015_RS01110 HMPREF3015_RS05675 RS08585 oxobutanoate -1'-deoxyribulose hydroxybutanoate 3-oxoacyl-ACP HMPREF3015_RS04005 methylenetetrahydrofolate HMPREF3015_RS12190 HMPREF3015_RS05380 HMPREF3015_RS05065 HMPREF3015_RS15355 5-[(5-phosphoribosylamino) HMPREF3015_RS22185 semialdehyde HMPREF3015_RS08260 NADP-specific glutamate N-acetyl-D- a single-stranded a ribonucleoside a dipeptide butanoyl 4-phosphate 5'-phosphate D-ala reductase FabG: a trans-2- methenyltetrahydrofolate dehydrogenase/ dipalmitoyl amino acid (2E,7Z)- roseoflavin adenineHMPREF3015_RS05035 acetylornithine (2S,4S)-4- 2-aceto-2-hydroxy- a 2,3,4-saturated D-sorbitol degradation I oligodeoxyribonucleotide 5'-monophosphate acyl-carrier protein DMKH2-13 a glycogen RS03520 methylideneamino]imidazole- HMPREF3015_RS22190 dehydrogenase: HMPREF3015_RS11825 enoyl-[acyl- muramate 6- cyclohydrolase: methenyltetrahydrofolate phosphatidate phosphate (indol-3-yl)acetate (R)-lactaldehyde an alcohol RS01940 2-isopropylmalate branched-chain amino aspartate-semialdehyde hydroxy-2,3,4,5- indole-3-glycerol butanoate fatty acyl-[acp] hexadecenoyl-CoA dinucleotide 4-carboxamide (S)-2-aceto-2- aminotransferase: HMPREF3015_RS06975 a (3R)-3- carrier protein] phosphate HMPREF3015_RS13955 cyclohydrolase: synthase: acid aminotransferase: dehydrogenase: tetrahydrodipicolinate phosphate synthase TrpC: isomeroreductase: 1-(5-phosphoribosyl)-5- hydroxybutanoate HMPREF3015_RS01065 NADP-specific glutamate hydroxydodecanoyl- N-acetylmuramic acid D-sorbitol HMPREF3015_RS19635 HMPREF3015_RS11475 HMPREF3015_RS06675 HMPREF3015_RS22175 a 5,10- HMPREF3015_RS13955 HMPREF3015_RS03525 4-hydroxy- [acp] 6-phosphate etherase: sorbitol dehydrogenase: a [glycine-cleavage 1-cis-vaccenoyl- GlcMan GlcNAc a 2'- a (1->4)- [(5- phosphoribosylamino) ketol-acid N-acetyl-L- dehydrogenase: methenyltetrahydrofolate 9 2 (2S)- RS23575 2-isopropylmalate tetrahydrodipicolinate (1S,2R)-1-C-(indol-3- (R)-2,3-dihydroxy- a 5,10- a cis- isoprimeverose carboxynorspermidine oleoyl-CoA chloramphenicol 3-ethylmalate methylideneamino]imidazole- reductoisomerase: ornithine L-aspartate- HMPREF3015_RS07025 bifunctional UDP-3-O- HMPREF3015_RS03440 HMPREF3015_RS12130 SAM complex H protein] a sulfurated [sulfur carrier] sn-glycerol- -[protein] deoxyribonucleoside [DNA] ethylmalonyl-CoA α-D-glucan synthase: hydrogencarbonate reductase: yl)glycerol 3-phosphate 3-methylpentanoate N-acetyl-D- bifunctional methenyltetrahydrofolate 6 vaccenoyl-[acp] alpha-1,2-mannosidase: 4- carboxamide isomerase: val HMPREF3015_RS22175 semialdehyde [3-hydroxymyristoyl] sorbitol dehydrogenase: N -octanoyl-L-lysine 3-phosphate1-acyl-sn-glycerol-3- 5'-triphosphate DNA polymerase I: carboxynorspermidine methylmalonyl- chloramphenicol 3-isopropylmalate 1,4-alpha-glucan- RS05865 HMPREF3015_RS19650 acetylornithine HMPREF3015_RS03655 glu glucosamine methylenetetrahydrofolate bifunctional lipoyl synthase: alpha-xylosidase: HMPREF3015_RS07310 acyl-CoA dehydrogenase: RS16475 HMPREF3015_RS20480 tryptophan synthase: 2,3-dihydroxy-3- N-acetylglucosamine HMPREF3015_RS03270 HMPREF3015_RS01750 CoA epimerase: acetyltransferase: dehydrogenase: branching protein: (R)-2,3-dihydroxy- deacetylase: 4-hydroxy- biotin-carboxyl carrier protein assembly dehydrogenase/ HMPREF3015_RS03965 phosphate acyltransferase: HMPREF3015_RS09680 D-glucosyl- Man GlcNAc - decarboxylase: (S)-2,3,4,5- HMPREF3015_RS06665 methylvalerate hydro-lyase: deacetylase/3-hydroxyacyl- 6-phosphate keto-D-fructose methylenetetrahydrofolate a [glycine-cleavage 8 2 HMPREF3015_RS01890 HMPREF3015_RS05675 phosphoribulosylformimino- 3-methylpentanoate HMPREF3015_RS21745 tetrahydrodipicolinate an unsulfurated HMPREF3015_RS121901,2-dicis- α(1->3)- α- [protein] (isomer [+ 7 isozymes] HMPREF3015_RS25455 HMPREF3015_RS00560 HMPREF3015_RS25625 HMPREF3015_RS19655 (2S)-2- tetrahydrodipicolinate HMPREF3015_RS06695 HMPREF3015_RS22195 ACP dehydratase: N-acetylglucosamine-6- methenyltetrahydrofolate dehydrogenase/ 5'-deoxyadenosine met complex H protein] AICAR-phosphate 2,3-dihydroxy-3- synthase: a [biotin carboxyl- [sulfur carrier] acyl-carrier protein vaccenoyl- α-D-xylopyranose D-glucopyranose D-mannose 8A B ) [DNA] (2E,9Z)- (2R)- chloramphenicol starch isopropylmalate phosphate deacetylase: cyclohydrolase: methenyltetrahydrofolate N 6 -lipoyl-L-lysine 1,2,3 1,2 norspermidine 2-oxovalerate RS18720 carbamoyl tryptophan synthase (S)-3-methyl-2- HMPREF3015_RS04005 carrier protein]-L-lysine octadecenoyl-CoA ethylmalonyl-CoA 3-acetate methylvalerate hydro-lyase: L-ornithine HMPREF3015_RS08260 HMPREF3015_RS25490 HMPREF3015_RS13955 cyclohydrolase: phosphatidate 3-isopropylmalate phosphate (2S,4S)-4- subunit beta: oxopentanoate HMPREF3015_RS22195 a (2E)-dodec- biotin--[acetyl-CoA- imidazole glycerol dehydratase: [+ 2 isozymes] an N 10 - HMPREF3015_RS13955 RS02055 RS15500 hydroxy-2,3,4,5- HMPREF3015_RS06695 branched-chain amino 2-enoyl-[acp] carboxylase] ligase: β-D-fructofuranose phosphate synthase: HMPREF3015_RS19640 (S)-3-methyl-2- L-α-amino-ε- D-glucosamine formyltetrahydrofolate a 5,10- 5,10-methylene- 3-methyl-2- 1-palmitoyl- an N-acetyl-β- a supercoiled tetrahydrodipicolinate acid aminotransferase: HMPREF3015_RS15900 an N-modified xanthan an adenine in DNA prephenate orotidine 5'- HMPREF3015_RS20475 oxopentanoate keto-pimelate indole ser 6-phosphate sn-glycerol a myristoyl-[acp] D-hexosaminide cis-vaccenoyl-CoA MeOH HMPREF3015_RS19645 4-hydroxy- HMPREF3015_RS11475 L-cysteine biosynthesis hexokinase: formyltetrahydrofolate methylenetetrahydrofolate tetrahydromethanopterin oxobutanoate aminoacyl-[tRNA] duplex DNA phosphate HMPREF3015_RS20485 a [biotin carboxyl-carrier 3-methyl-2-oxobutanoate 3-phosphate xanthan lyase: beta-hexosaminidase: branched-chain amino tetrahydrodipicolinate diaminopimelate phosphoglucosamine HMPREF3015_RS12785 deformylase: 1-acyl-sn-glycerol-3- replicative DNA helicase: orotidine-5'-phosphate RS21295 2-isopropylmaleate VI (from L-methionine) protein]-N 6 -biotinyl-L-lysine hydroxymethyltransferase: aminoacyl-tRNA hydrolase: HMPREF3015_RS09910 HMPREF3015_RS18525 acyl-CoA dehydrogenase: DNA adenine methylase: prephenate dehydratase: catalase: acid aminotransferase: reductase: dehydrogenase: ile mutase: HMPREF3015_RS20490 phosphate acyltransferase: HMPREF3015_RS18735 4-deoxy-α-L- HMPREF3015_RS20200 decarboxylase: D-erythro- L-citrulline tryptophan synthase F6P HMPREF3015_RS25605 β-D-Man- [+ 6 isozymes] HMPREF3015_RS01890 HMPREF3015_RS02700 HMPREF3015_RS11680 HMPREF3015_RS06980 AICAR HMPREF3015_RS11475 HMPREF3015_RS03655 HMPREF3015_RS07070 HMPREF3015_RS11890 HMPREF3015_RS121901-palmitoyl- an N-modified an uncharged threo-hex-4- [+ 14 isozymes] HMPREF3015_RS04020 RS03215 imidazole-glycerol- 3-isopropylmalate subunit beta: met a dodecanoyl-[acp] formate 4,6-pyruvate an N-acetyl-β- RS05910 THMPT 2-dehydropantoate acyl-carrier protein 2-myristoyl amino acid tRNA enopyranoside an alcohol (2E,11Z)- an N 6 -methyladenine keto- a single UMP phosphate dehydratase: argininosuccinate synthase: (S)-2,3,4,5- meso- HMPREF3015_RS06695 methionine D-glucosamine D-hexosamine formaldehyde ile a [biotin carboxyl- phosphatidate octadecenoyl-CoA in DNA phenylpyruvate stranded DNA bifunctional histidinol- HMPREF3015_RS19640 HMPREF3015_RS01075 tetrahydrodipicolinate diaminopimelate adenosyltransferase: 1-phosphate acyl-ACP thioesterase: carrier-protein dimer]- phosphatase/ HMPREF3015_RS19645 LL-diaminopimelate HMPREF3015_RS05720 beta-ketoacyl-[acyl-carrier- RS04850 L-arginino- diaminopimelate trp protein] synthase II: HMPREF3015_RS22180 N 6 -biotinyl-L-lysine imidazoleglycerol- (2R,3S)-3- aminotransferase: decarboxylase: SAM 7,8-dihydrofolate a DNA containing (7Z)- 3-[(3'-methylthio) succinate HMPREF3015_RS17205 acetyl-CoA carboxylase a homogalacturonan NADPH H + an unsulfurated N-acetyl- NaMN ethanol glycochenodeoxycholate phosphate isopropylmalate HMPREF3015_RS06760 HMPREF3015_RS20455 N-acetyl-α-D- a palmitoleoyl-[acp] a malonyl-[acp] monoglutamate an apurinic/ cys tetradecenoyl-CoA propyl]malate RS08915 argininosuccinate lyase: biotin carboxylase subunit: pectate lyase: [sulfur carrier] L-citrulline RS20920 dehydratase HisB: 3-isopropylmalate laurate glucosamine beta-ketoacyl-[acyl-carrier- dihydrofolate reductase: apyrimidinic site acetylornithine 3-isopropylmalate L-proline biosynthesis I superpathway of L-serine HMPREF3015_RS07490 L,L- acetyl-CoA carboxylase: HMPREF3015_RS05290 HMPREF3015_RS01005 endonuclease III: cysteine desulfurase: acyl-CoA dehydrogenase: 5'-nucleotidase: catalase: HMPREF3015_RS10095 dehydrogenase: lys a 3-oxotetradecanoyl- 1-phosphate protein] synthase II: HMPREF3015_RS22035 deacetylase: dehydrogenase: and glycine biosynthesis I diaminopimelate long-chain fatty HMPREF3015_RS09640 acetyl-CoA carboxylase [+ 5 isozymes] HMPREF3015_RS00480 HMPREF3015_RS07755 HMPREF3015_RS01890 HMPREF3015_RS04825 HMPREF3015_RS06980 HMPREF3015_RS19655 [acp] HMPREF3015_RS17205 [+ 3 isozymes] a 3'-terminal a 5'-phospho- HMPREF3015_RS19655 imidazole acetol- an unsaturated pectate an (11Z)-3- tetrahydropteroyl a sulfurated HMPREF3015_RS21745 gly chenodeoxycholate arg diaminopimelate acid--CoA ligase: biotin carboxylase subunit: + ala RS03575 glu 3-phospho- superpathway of sulfate assimilation and cysteine biosynthesis SAH 3-oxoacyl-ACP a homogalacturonan NADP unsaturated sugar [DNA] (2E,7Z)- 6-(methylthio)- β-D- phosphate (2S)-2-isopropyl- epimerase: HMPREF3015_RS21750 HMPREF3015_RS04655 Nucleoside and Nucleotide Degradation oligosaccharide acyl-carrier protein oxooctadec- mono-L-glutamate [sulfur carrier] acetate L-citrulline acetaldehyde glutamate 5-kinase: D-glycerate reductase FabG: tetradecenoyl-CoA 2-oxohexanoate ribosylnicotinate histidinol-phosphate 3-oxosuccinate 3-phosphoglycerate HMPREF3015_RS06765 a [carboxyl-carrier UDP-N-acetyl- 11-enoyl-[acp] RS21490 3-phospho- [+ 3 isozymes] RS24920 transaminase: HMPREF3015_RS07420 dehydrogenase: APS MTA/SAH nucleosidase: HMPREF3015_RS11825 protein dimer]-N 6 - α-D-glucosamine γ-L-glutamyl meso- D-glycerate a (3R)-3- superpathway of purine deoxyribonucleosides degradation HMPREF3015_RS23600 ATP 3-phosphoglycerate HMPREF3015_RS12140 lauroyl-CoA UDP-N-acetylglucosamine inosine 5'-phosphate HMPREF3015_RS10100 5-phosphate diaminopimelate adenylyl-sulfate kinase: carboxybiotinyl-L-lysine a [methyl-(Co(III) an N-formyl-L- (indol-3- (5Z)- 3-[(5'-methylthio) (2R,3S)-3- 3-phosphooxypyruvate sulfate adenylyltransferase: hydroxytetradecanoyl- degradation coenzyme A preuroporphyrinogen an aryl sulfate glycocholate L-histidinol L-homoserine biosynthesis HMPREF3015_RS21205 dehydrogenase: 1-carboxyvinyltransferase: CAIR asp tetramethylammonium- coenzyme M methionylaminoacyl- asp fumarate 4-methyl-2- glutamate-5-semialdehyde diaminopimelate S-ribosyl-L- [acp] yl)pyruvate tetradecenoyl-CoA pentyl]malate isopropylmalate RS16710 HMPREF3015_RS21210 HMPREF3015_RS23600 HMPREF3015_RS05415 specific corrinoid protein] tRNA indolepyruvate ferredoxin phosphate oxopentanoate dehydrogenase: 3-phosphoserine PAPS homocysteine bifunctional UDP-3-O- Aromatic Compound 2'-deoxyguanosine phosphoribosylaminoimidazolesuccinocarboxamide methylcobamide--CoM peptide deformylase: L-aspartate oxidase: uroporphyrinogen- 3-isopropylmalate 3-isopropylmalate sulfatase: decarboxylase: HMPREF3015_RS21215 3-phosphooxypyruvate UDP-N-acetyl-α- oxidoreductase: acyl-CoA dehydrogenase: branched-chain amino HMPREF3015_RS07405 aminotransferase: APS [3-hydroxymyristoyl] Biosynthesis IMP synthase: HMPREF3015_RS04065 methyltransferase: HMPREF3015_RS21240 HMPREF3015_RS05840 III synthase: dehydrogenase: dehydrogenase: HMPREF3015_RS19665 RS03325 bifunctional histidinol- asp HMPREF3015_RS20455 D-glucosamine- 2'-deoxyadenosine HMPREF3015_RS21290 HMPREF3015_RS01890 RS14805 acid aminotransferase: HMPREF3015_RS23595 3-phosphoserine L-methionine biosynthesis III N-acetylglucosamine SAICAR a [Co(I) HMPREF3015_RS09660 a L-methionylaminoacyl- succinate 2-iminosuccinate HMPREF3015_RS01675 HMPREF3015_RS19655 HMPREF3015_RS19655 [+ 2 isozymes] gly cholate phosphatase/ L-glutamate-5- bifunctional aspartate stearate biosynthesis chorismate biosynthesis I enolpyruvate IMP dehydrogenase: formate S-2-(indol-3 HMPREF3015_RS11475 lys aminotransferase: deacetylase/3-hydroxyacyl- tetramethylammonium- methyl-CoM tRNA (2E,5Z)- 8-(methylthio)- 4-methyl-2- imidazoleglycerol- semialdehyde 3-phospho- kinase/homoserine II (bacteria and plants) UDP-N-acetylmuramate purine-nucleoside HMPREF3015_RS14520 yl)acetyl-CoA uroporphyrinogen-III a phenol HMPREF3015_RS23595 ACP dehydratase: specific corrinoid protein] tetradecenoyl-CoA 2-oxooctanoate oxopentanoate phosphate L-serine dehydrogenase I: D-erythrose dehydrogenase: phosphorylase: RS19500 leu L-homocysteine L-homoserine HMPREF3015_RS04005 XMP dehydratase HisB: HMPREF3015_RS15475 3-phospho- 4-phosphate HMPREF3015_RS20420 HMPREF3015_RS12900 phosphoserine S-adenosyl-L-methionine cycle II L-isoleucine biosynthesis V homoserine O- a palmitoyl-[acp] HMPREF3015_RS10095 L-serine a (2E)-tetradec- purine-nucleoside Man GlcNAc -[protein] a 1-acyl-sn luteolin 7-O-[β-D- β a 2'- phosphatase SerB: [+ 2 isozymes] acetyltransferase: UDP-N-acetyl- 8 2 a 1-phosphatidyl- -D-glucopyranose 3-[(4'-methylthio) RS16605 RS03405 3-oxo-stearoyl- phosphorylase: an acyl-[acyl- a dihydroceramide maltotriose D-threo-isocitrate maltose propionamide (S)-1-pyrroline- L-aspartyl- 2-enoyl-[acp] α 5'-nucleotidase: (isomer 8A B ) -glycerol 3- glucosyluronate-(1,2)-β- 1-phosphate deoxyribonucleoside [DNA] histidinol HMPREF3015_RS17585 phosphoserine HMPREF3015_RS09115 [acp] synthase: -D-muramate 2'-deoxyinosine 1,2,3 1,3 carrier protein] 1D-myo-inositol butyl]malate 4-phosphate 2-methylbutanoate O-acetyl-L- HMPREF3015_RS12900 HMPREF3015_RS04825 alpha-1,2-mannosidase: phosphate D-glucosiduronate]-4'- alpha-glucosidase: alpha-glucosidase: 5'-triphosphate 5-carboxylate met phosphatase SerB: hydrogen sulfide HMPREF3015_RS11820 3-deoxy- 1-acyl-sn-glycerol-3- NADP-dependent 3-isopropylmalate ser methionine homoserine a 3-oxooctadecanoyl- purine-nucleoside HMPREF3015_RS07310 O-β-D-glucosiduronate HMPREF3015_RS02325 beta-phosphoglucomutase: HMPREF3015_RS02325 amidase: histidinol dehydrogenase: pyrroline-5- aspartate-semialdehyde acetyl-CoA synthetase: HMPREF3015_RS17585 Man GlcNAc - phosphate acyltransferase: beta-glucuronidase: isocitrate dehydrogenase: dehydrogenase: L-cystathionine D-arabino- 5 2 [+ 8 isozymes] RS25580 adenosyltransferase: [acp] phosphorylase: β-D-mannopyranose a 1,2-diacyl- an inositol HMPREF3015_RS16395 [+ 8 isozymes] HMPREF3015_RS03460 HMPREF3015_RS10105 carboxylate reductase: dehydrogenase: HMPREF3015_RS01050 O-acetylhomoserine heptulosonate xanthosine [protein] (isomer 5A ) HMPREF3015_RS12190a 1,2-diacyl- HMPREF3015_RS04385β HMPREF3015_RS22155 HMPREF3015_RS19655 [DNA] HMPREF3015_RS05720 2-methylbutanoyl- UDP-N-acetyl- 1,2 β luteolin 7-O- - sn-glycerol phosphodihydroceramide β HMPREF3015_RS01060 serine methionine synthase: ser sulfhydrylase: 3-oxoacyl-ACP 2-deoxy-α-D- HMPREF3015_RS12900 sn-glycerol -D-glucuronate D-glucopyranose maltose -D-glucose 7-(methylthio)-2- D-glucopyranose RS24935 HMPREF3015_RS03525 CoA 7-phosphate α acyl-carrier protein D-diglucuronide 2-oxoglutarate propanoate RS12085 histidinal hydroxymethyltransferase: glyA HMPREF3015_RS10210 HMPREF3015_RS00925 a myristoyl-[acp] reductase FabG: -D-muramoyl- ribose 1-phosphate 6-phosphate oxoheptanoate pyrroline-5- L-aspartate- 3-dehydroquinate synthase: γ purine-nucleoside 3-phosphate [+ 2 isozymes] serine acetyltransferase: [+ 2 isozymes] HMPREF3015_RS11825 L-alanyl- -D- carboxylate reductase: semialdehyde beta-ketoacyl-[acyl-carrier- HMPREF3015_RS01335 phosphorylase: histidinol dehydrogenase: HMPREF3015_RS01535 a (3R)-3- glutamyl-meso-2,6- HMPREF3015_RS04785 gly protein] synthase II: HMPREF3015_RS12900 Man GlcNAc -[protein] α-D- cys L-homocysteine hydroxyoctadecanoyl- diaminopimelate guanosine nucleotides 8 2 10 a [protein] N-terminal- 3-[(6'-methylthio) phosphoenol HMPREF3015_RS10105 bifunctional aspartate [+ 2 isozymes] an N - an L-methionyl- D-glucopyranose 2+ L-homocysteine SAM (S)-3-methyl-2- HMPREF3015_RS17205 3-dehydroquinate (isomer 8A B ) F6P glucopyranose CTP NADH D-glycerate protoporphyrin IX Mg [acp] 2-deoxy-D-ribose degradation III 1,2,3 2,3 Met formyl-L-methionine hexyl]malate pyruvate pro kinase/homoserine xanthine alpha-1,2-mannosidase: formyltetrahydrofolate [initiator tRNA ] oxopentanoate methionine synthase: methionine synthase: 5-phosphate methionyl-tRNA fructose-6- peptide deformylase: 1-phosphate NAD(+) diphosphatase: RS02845 his dehydrogenase I: O-acetyl-L-serine a 3-oxohexadecanoyl- bifunctional UDP-3-O- type II 3-dehydroquinate glucose-1-phosphate 3-isopropylmalate xylose isomerase: RS17435 branched-chain amino HMPREF3015_RS07310 phosphate aldolase: HMPREF3015_RS21240 glycerate dehydrogenase: pyruvate kinase: HMPREF3015_RS15475 HMPREF3015_RS10210 HMPREF3015_RS09665 [acp] [3-hydroxymyristoyl] Man GlcNAc -[protein] formyltransferase: HMPREF3015_RS14275 dehydrogenase: dehydratase: 7 2 cytidylyltransferase: HMPREF3015_RS22735 HMPREF3015_RS05500 HMPREF3015_RS15150 acid aminotransferase: cysteine synthase A: [+ 2 isozymes] [+ 2 isozymes] deoxyribose- GMP β-D-mannopyranose HMPREF3015_RS11865 HMPREF3015_RS18460 an N-terminal L- reduced β- Mg- S-adenosyl-L-methionine cycle I N-acetylglucosamine HMPREF3015_RS15145 (isomer 7A B ) an N-formyl- formate HMPREF3015_RS20335 HMPREF3015_RS19655 superpathway of L-asparagine biosynthesis HMPREF3015_RS11475 HMPREF3015_RS19670 3-oxoacyl-ACP 1,2,3 2 D-glyceraldehyde methionyl-[protein] nicotinamide D- AMP protoporphyrin L-homoserine deacetylase/3-hydroxyacyl- phosphate aldolase: 5'-nucleotidase: L-methionyl- a tetrahydrofolate dihydroxyacetone CDP-α-D-glucose 9-(methylthio)- keto-D-fructose adenosylhomocysteinase: met reductase FabG: 3-phosphate ribonucleotide hydroxypyruvate pyruvate [+ 3 isozymes] ACP dehydratase: 3-dehydroshikimate HMPREF3015_RS01730 HMPREF3015_RS04825 urate [initiator tRNA met ] 2-oxononanoate SAM HMPREF3015_RS09465 ile HMPREF3015_RS11825 asp a (3R)-3- HMPREF3015_RS04005 RS09570 SAH cys shikimate shikimate 5- D-glyceraldehyde guanosine RS12225 hydroxyhexadecanoyl- a (2E)-octadec- dehydrogenase: dehydrogenase: acetaldehyde Man GlcNAc -[protein] a tRNA precursor with a (1->4)- UTP 3-phosphate 7 2 5-amino-4- a [protein]- an organic O-ureido-L- orotidine 5'- 3-[(7'-methylthio) methionine [acp] 2-enoyl-[acp] purine-nucleoside (isomer 7A B ) a 5' extension and PRPP asp a 7,8-dihydrofolate α-D-glucan pyrazinamide asparagine aroE aroE 1,2,3 3 imidazolecarboxyamide L-cysteine hydroperoxide heptyl]malate adenosyltransferase: aspartate--ammonia ligase: bifunctional UDP-3-O- alpha-1,2-mannosidase: homoserine phosphate nucleoside triphosphate L-glutamine L-alanine biosynthesis III phosphorylase: a short 3' extensionribonuclease P adenine peroxiredoxin: orotate dihydrofolate reductase: 3-isopropylmalate 1,4-alpha-glucan- HMPREF3015_RS05720 synthase HMPREF3015_RS16375 adenosine nucleotides argininosuccinate synthase: pyrophosphohydrolase: biosynthesis I [3-hydroxymyristoyl] shikimate HMPREF3015_RS12900 HMPREF3015_RS07310 protein component: phosphoribosyltransferase: HMPREF3015_RS15350 phosphoribosyltransferase: branching protein: amidase: B: asnB asparagine degradation III Man GlcNAc -[protein] HMPREF3015_RS01075 HMPREF3015_RS19690 dehydrogenase: HMPREF3015_RS11045 met SAH N-acetylglucosamine β-D-mannopyranose 6 2 HMPREF3015_RS01670 HMPREF3015_RS01710 an intra- HMPREF3015_RS07480 HMPREF3015_RS05675 HMPREF3015_RS03460 RS06540 synthase acetyl-CoA (isomer 6A ) an alcohol canavaninosuccinate [+ 3 isozymes] HMPREF3015_RS19655 RS03715 cys deacetylase/3-hydroxyacyl- shikimate kinase: 1,2,3 a tRNA precursor with protein disulfide UMP glu guanine a tRNA fragment AICAR orotate PRPP 10-(methylthio)- a GlgE-glycogen pyrazine-2- B: asnB ACP dehydratase: a stearoyl-[acp] a short 3' extension a folate asn glutamine synthetase: cysteine desulfurase: HMPREF3015_RS07665 AMP 2-oxodecanoate carboxylate MTA/SAH nucleosidase: HMPREF3015_RS04005 methionine synthase: HMPREF3015_RS12140 HMPREF3015_RS11100 HMPREF3015_RS07755 shikimate 3- acyl-ACP thioesterase: AMP nucleosidase: HMPREF3015_RS10210 asn [+ 2 isozymes] ala a (2E)-hexadec- phosphate HMPREF3015_RS22180 HMPREF3015_RS08225 Man GlcNAc -[protein] a (1->6)- a β-D-glucosyl-N uridine [+ 2 isozymes] S-ribosyl-L- gln 2-enoyl-[acp] 8 2 an (R)-2- an L-cysteinyl- (5Z)- D-mannopyranose acetylxylan L-homocysteine 3-phosphoshikimate 1- (isomer 8A B ) α a [protein]-L-glutamine serotonin oxaloacetate 1,2,3 1,2 -D-glucan -acylsphingosine Cys RS10745 RS00150 homocysteine xanthine adenine halocarboxylate [tRNA ] dodecenoyl-CoA stearate carboxyvinyltransferase: alpha-1,2-mannosidase: cycloisomaltooligosaccharide transglutaminase domain- glucosylceramidase: HAD family hydrolase: acetylxylan esterase: uridine kinase: aminoacyl-tRNA hydrolase: hexokinase: citrate/2-methylcitrate HMPREF3015_RS16110 purine ribonucleosides degradation HMPREF3015_RS07310 containing protein: HMPREF3015_RS00140 acyl-CoA dehydrogenase: HMPREF3015_RS16620 HMPREF3015_RS10190 Man GlcNAc -[protein] glucanotransferase: HMPREF3015_RS03915 synthase: long-chain fatty 5-enolpyruvoyl- 7 2 a sphingosine HMPREF3015_RS18735 HMPREF3015_RS01890 HMPREF3015_RS12785 β-D-mannopyranose HMPREF3015_RS17335 HMPREF3015_RS12025 D-glucopyranose an (R)-2- [+ 3 isozymes] (isomer 7A B ) 6 a halide anion HMPREF3015_RS22150 acid--CoA ligase: shikimate 3- 1,2 1,2 a [protein] N -[(5-hydroxy-1H ceramide hydroxyacid a tRNA Cys UMP cys (2E,5Z)- D-mannopyranose acetate xylan (2S,3S)-2- a palmitoyl-[acp] HMPREF3015_RS21750 phosphate a cycloisomaltooligosaccharide -indol-3-yl)ethyl]-L-glutamine urate adenosine dodecenoyl-CoA 6-phosphate methylcitrate RS11845 [+ 3 isozymes] chorismate synthase: RS15670 acyl-ACP thioesterase: HMPREF3015_RS22225 HMPREF3015_RS22180 stearoyl-CoA Man GlcNAc -[protein] β 9 2 N-acetyl- - hydrogen methyl-esterified maltohexaose + xylan D-altropyranose chorismate (isomer 9A B ) DL-allothreonine neuraminate H NADH a protein (S)-dihydroorotate oxaloacetate homogalacturonan palmitate acyl-[acyl-carrier protein] 1,2,3 1,2,3 peroxide alpha-1,2-mannosidase: alpha-glucosidase: N-acetylneuraminate lyase: NADH peroxidase: thioesterase pathway serine endopeptidase La: dihydroorotate alpha-xylosidase: L-fucose isomerase: citrate/2-methylcitrate HMPREF3015_RS07310 HMPREF3015_RS02325 HMPREF3015_RS04495 HMPREF3015_RS10030 RS09150 long-chain fatty xanthosine adenosine inosine guanosine Man GlcNAc - hydroxymethyltransferase: glyA β HMPREF3015_RS17605 dehydrogenase HMPREF3015_RS09680 HMPREF3015_RS06075 synthase: RS17990 β-D-mannopyranose 5 2 [+ 8 isozymes] N-acetyl- -D- acid--CoA ligase: an acyl-[acyl- [protein] (isomer 5A ) pyruvate NAD + H O electron transfer subunit: HMPREF3015_RS22150 MeOH a homogalacturonan 1,2 mannosamine 2 carrier protein] gly acetaldehyde D-glucopyranose maltopentaose a peptide a peptide HMPREF3015_RS08240 α HMPREF3015_RS21750 -D-xylopyranose keto-D-psicose citrate [+ 3 isozymes] acyl-ACP thioesterase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside orotate HMPREF3015_RS22180 phosphorylase: phosphorylase: phosphorylase: phosphorylase: palmitoyl-CoA a fatty acid HMPREF3015_RS12900 HMPREF3015_RS12900 HMPREF3015_RS12900 HMPREF3015_RS12900 Man GlcNAc -[protein] a dolichyl β- RS04575 7 2 RNase R degradation RS02585 a homogalacturonan N-acetylneuraminate hydrogencarbonate + NMN sec ethylene glycol a colanic acid lipid A-core (isomer 7A B ) substrate RNA H a protein a tRNA ser D-mannosyl a [protein] Ser/Thr α-D-ribose- 1,2 1,2 alpha-1,2-mannosidase: polygalacturonase: ribonuclease R: N-acetylneuraminate lyase: carbonic anhydrase: phosphate 1-phosphate clostripain: serine--tRNA ligase: HMPREF3015_RS07310 HMPREF3015_RS01045 HMPREF3015_RS08880 HMPREF3015_RS04495 HMPREF3015_RS00540 5'-nucleotidase: lactaldehyde reductase: pyrimidine deoxyribonucleotides Man GlcNAc -[protein] HMPREF3015_RS09455 HMPREF3015_RS11285 β-D-mannopyranose 6 2 [+ 2 isozymes] a nucleoside 5'- N-acetyl-D- HMPREF3015_RS04825 a 3-O-(α-D- HMPREF3015_RS01110 E. coli M (isomer 6A B ) a diribonucleotide pyruvate H O CO an L-seryl- a dolichyl LPS dephosphorylation UTP and CTP dephosphorylation I 1,2 2 mannosamine 2 2 a homogalacturonan a homogalacturonan monophosphate a peptide a peptide 1-(β-D ribofuranosyl) sec mannosyl)-(Ser/ nucleoside triphosphate [tRNA ] phosphate glycolaldehyde nicotinamide Thr)-[protein] pyrophosphohydrolase: D-ribose 5- UTP HMPREF3015_RS11045 phosphate dCTP dCMP CTP synthase: Man GlcNAc -[protein] a β-D- β a dipetide with an N- cytidine 2',3'-cyclic uridine 2'3'-cyclic a glucosylated 6 2 a sialyloligosaccharide an (R)-2- luteolin 7-O- - a (1->4)-α-D-glucan (isomer 6A B ) fructofuranoside monophosphate monophosphate HMPREF3015_RS22025 1,2 1 halocarboxylate D-glucuronide terminal L-aspartate glycogenin alpha-1,2-mannosidase: neuraminidase: invertase: dipeptidase: 2',3'-cyclic-nucleotide 2',3'-cyclic-nucleotide dUTP diphosphatase: UMP HAD family hydrolase: beta-glucuronidase: 1,4-alpha-glucan- 1,4-alpha-glucan- HMPREF3015_RS07310 HMPREF3015_RS07205 HMPREF3015_RS18890 HMPREF3015_RS04385 HMPREF3015_RS22230 2'-phosphodiesterase: 2'-phosphodiesterase: branching protein: HMPREF3015_RS08055 CTP Man GlcNAc - HMPREF3015_RS03915 branching protein: 5'-nucleotidase: β-D-mannopyranose 5 2 [+ 2 isozymes] an (S)-2- a glycoside β-D-fructofuranose a proteinogenic HMPREF3015_RS05675 HMPREF3015_RS22350 HMPREF3015_RS22350 HMPREF3015_RS05675 nucleoside triphosphate [protein] (isomer 5A ) a halide anion β-D-glucuronate luteolin asp HMPREF3015_RS04825 1,2 N-acetylneuraminate hydroxycarboxylate amino acid a (1,6)-α-D-glucosyl- pyrophosphohydrolase: an oligosaccharide 3'-cmp 3'-UMP a glycogen uridine (1,4)-α-glucan HMPREF3015_RS11045 CMP dUTP dUMP 5'-nucleotidase: Man GlcNAc -protein di-trans,octa-cis UDP 7 2 RNase III mRNA an (S)-2- a fructan chitin cellulose HMPREF3015_RS04825 (isomer 7A B ) canavaninosuccinate UDP-α-D-glucose -undecaprenyl SAICAR 1,2,3alpha-1,2-mannosidase:1 processing substrate halocarboxylate ribonucleotide-diphosphate 5-hydroxy-CTP 5-hydroxy-CMP ribonuclease III: HAD family hydrolase: fructan beta-fructosidase: argininosuccinate lyase: phosphate beta-hexosaminidase: adenylosuccinate lyase: cytidine S-methyl-5'-thioadenosine HMPREF3015_RS07310 reductase subunit alpha: endoglucanase: HMPREF3015_RS17200 HMPREF3015_RS03915 HMPREF3015_RS07765 HMPREF3015_RS07490 HMPREF3015_RS18525 HMPREF3015_RS11335 degradation IV Man GlcNAc -[protein] HMPREF3015_RS08805 β 6 2 β α [+ 6 isozymes] HMPREF3015_RS03200 -D-mannopyranose RNase III processing a halide anion an (S)-2- a fructan -D-fructofuranose -D-glucopyranosyl- (isomer 6A B ) an mRNA fragment fumarate L-canavanine UMP N-acetyl-D- AICAR fumarate dUDP S-methyl-5'- 1,2 1 product mRNA hydroxycarboxylate diphosphoundecaprenol chitin glucosamine a cellodextrin thioadenosine MTA/SAH nucleosidase: HMPREF3015_RS12140 Man GlcNAc -[protein] 7,8- D-sedoheptulose D-glyceraldehyde D-erythrose D-xylulose p-nitrophenyl- an α-D- dCDP MTR 9 2 1-kestotriose H O acetyl-CoA carbonic acid (isomer 9A B ) 7-phosphate 3-phosphate 4-phosphate 5-phosphate α-D-glucuronide 2 glucuronoside 1,2,3 1,2,3 dihydromonapterin ribonucleotide-diphosphate alpha-1,2-mannosidase: fructan beta-fructosidase: transketolase: carbonic anhydrase: Inorganic Nutrient Metabolism dihydroneopterin aldolase: transketolase: acetyl-CoA hydrolase: reductase subunit alpha: HMPREF3015_RS07310 HMPREF3015_RS07765 HMPREF3015_RS09650 HMPREF3015_RS00540 Man GlcNAc -[protein] HMPREF3015_RS16295 HMPREF3015_RS09650 HMPREF3015_RS05815 HMPREF3015_RS08805 β 8 2 6-(hydroxymethyl) D-xylulose D-ribose 5- D-glyceraldehyde selenate reduction -D-mannopyranose (isomer 8A B ) glycolaldehyde sucrose D-fructofuranose F6P 4-nitrophenol D-glucopyranuronate acetate an alcohol D-glucopyranuronate CO H O 1,2,3 2,3 5-phosphate CDP 2 2 sulfate activation -7,8-dihydropterin phosphate 3-phosphate for sulfonation selenate sulfate adenylyltransferase: 2-aminoethylphosphonate sulfate degradation I HMPREF3015_RS21210 sulfate adenylyltransferase: HMPREF3015_RS21215 adenosine 5'- (2-aminoethyl) HMPREF3015_RS21210 phosphonate phosphoselenate 2-aminoethylphosphonate- HMPREF3015_RS21215 -pyruvate transaminase: APS HMPREF3015_RS05455 adenylyl-sulfate kinase: phosphonoacetaldehyde HMPREF3015_RS21205 selenite phosphonoacetaldehyde hydrolase: PAPS HMPREF3015_RS05450

acetaldehyde Detoxification selenodiglutathione

reactive oxygen species degradation superoxide arginine dependent radicals degradation acid resistance acetyl-CoA superoxide glutathioselenol superoxide arg superoxide dismutase: superoxide dismutase: biosynthetic arginine HMPREF3015_RS25425 HMPREF3015_RS25425 decarboxylase: hydrogen hydrogen peroxide HMPREF3015_RS07685 hydrogen selenide peroxide agmatine catalase: catalase: HMPREF3015_RS06980 HMPREF3015_RS06980 O 2 H O hydroxyl radical O 2 2

a dicarboxylate phosphate D-glucose 1-(β-D glycine betaine putrescine 3,5- a C4- an amino an amino a sugar 6- a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA phosphonate a nucleoside (S)-lactate ammonium chromate a nucleotide a polyamine phosphate ribofuranosyl) pro spermidine dimethoxytoluene dicarboxylate D-glucose D-glucose acid acid D-galactose L-rhamnose phosphate phosphate cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA ammonium a lipopolysaccharide a lipopolysaccharide phosphate nicotinamide predicted ABC RS14300 RS09850 RS04875 RS22700 RS19335 RS01665 RS06000 RS20465 RS11195 RS04635 RS15400 RS03020 RS09615 RS09670 RS06745 RS15610 RS05140 RS22660 RS14560 RS10900 RS08310 RS03190 RS01100 RS21515 RS05985 RS14715 RS00580 RS16550 RS14555 RS10850 RS10770 RS05190 RS05355 RS18940 RS22645 RS16270 RS25535 RS21750 RS15495 transporter of phosphate 1-(β-D glycine betaine putrescine 3,5- a C4- D-glucose D-glucose an amino L-rhamnose a sugar a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid phosphonate a nucleoside (S)-lactate ammonium chromate a nucleotide a polyamine phosphate ribofuranosyl) pro spermidine dimethoxytoluene dicarboxylate ammonium acid an amino a lipopolysaccharide a lipopolysaccharide D-galactose cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate phosphate phosphate nicotinamide acid D-glucose phosphate a dicarboxylate This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.