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Cell Circuitry || Science Teaches English || The Chicken Genome Is Hot || Magnets in Medicine SEPTEMBER 2002 www.hhmi.org/bulletin Leading Doublea Life It’s a stretch, but doctors who work bench to bedside say they wouldn’t do it any other way. FEATURES 14 On Human Terms 24 The Evolutionary War A small—some say too small—group of Efforts to undermine evolution education have physician-scientists believes the best science evolved into a 21st-century marketing cam- requires patient contact. paign that relies on legal acumen, manipulation By Marlene Cimons of scientific literature and grassroots tactics. 20 Engineering the Cell By Trisha Gura Adam Arkin sees the cell as a mechanical system. He hopes to transform molecular 28 Call of the Wild biology into a kind of cellular engineering Could quirky, new animal models help scien- and in the process, learn how to move cells tists learn how to regenerate human limbs or from sickness to health. avert the debilitating effects of a stroke? By M. Mitchell Waldrop By Kathryn Brown 24 In front of a crowd of 1,500, Ohio’s Board of Education heard testimony on whether students should learn about intelligent design in science class. DEPARTMENTS 2 NOTA BENE 33 PERSPECTIVE ulletin Intelligent Design Is a Cop-Out 4 LETTERS September 2002 || Volume 15 Number 3 NEWS AND NOTES HHMI TRUSTEES PRESIDENT’S LETTER 5 JAMES A. BAKER, III, ESQ. 34 Senior Partner, Baker & Botts A Creative Influence In from the Fields ALEXANDER G. BEARN, M.D. Executive Officer, American Philosophical Society 35 Lost on the Tip of the Tongue Adjunct Professor, The Rockefeller University UP FRONT Professor Emeritus of Medicine, Cornell University Medical College 36 Biology by Numbers FRANK WILLIAM GAY 6 Follow the Songbird Former President and Chief Executive Officer, SUMMA Corporation JAMES H. -
BANCROFTIANA Number 145 • University of California, Berkeley • Fall 2014
Newsletter of The Friends of The Bancroft Library BANCROFTIANA Number 145 • University of California, Berkeley • Fall 2014 CALIFORNIA Captured On Canvas alifornia Captured on Canvas represents a first for The John superseded John Singer Sargent as the most important CBancroft Library Gallery. The exhibit focuses exclu- and fashionable portrait painter in England. As famous for sively on the Pictorial Collection’s more than 300 paintings. his bohemian life as he was for his bravura portraits, John With the exception of the 120 framed works in the Robert is said to have been the model for Alec Guinness’s character B. Honeyman, Jr. Collection of Early Californian and West- Gulley Jimson in the film The Horse’s Mouth. (Interestingly, ern American Pictorial Material—acquired by the Friends of John painted both T. E. Lawrence’s and King Faisal’s por- The Bancroft Library and the UC Regents in 1963—most of traits. Alec Guinness portrayed Faisal in David Lean’s epic the impressive array of framed works in the Pictorial Collec- film, Lawrence of Arabia.) tion are the result of individual donations or transfers from The inclusion of John Sackas’s colorful paintings collections acquired by gift or purchase. These works range documenting the Golden Gate Produce Market in the late not only in subject matter and geography—portraits from 1950s, before it was torn down in 1962 to make way for the Mexico, landscapes of Utah and the American Southwest— Embarcadero Center, and a study for a mural by Carleton but they also vary in medium from delicate pencil sketches, Lehman, painted on the verso of his portrait of Inez Ghi- watercolors, gouaches, ink and wash drawings, engravings, rardelli, expands the scope of this exhibition beyond the hand-colored lithographs, and photographs to oils on Continued on page 4 canvas, board, and paper. -
The Student Uprising That Ushered in the Radical Sixties: the Berkeley Free Speech Movement
The Student Uprising That Ushered In the Radical Sixties: The Berkeley Free Speech Movement Book Review: Hal Draper, Berkeley, The New Student Revolt. Haymarket, 2020. Thomas Harrison The current mass upheaval has reached a scale not seen in this country since the 1960s. So it is timely that Haymarket Books has republished an account of one of the key revolts in that fabled decade – the 1964 Free Speech Movement (FSM) at the University of California at Berkeley. Originally issued by Grove Press in 1965 and published in a second edition in 2010 by the Center for Socialist History, Hal Draper’s book remains the most vivid narrative and incisive analysis of the FSM that I know. A Marxist scholar of immense learning and a veteran of the revolutionary socialist movement, he was also a deeply involved participant in the FSM itself. Indeed, Draper’s influence led UC President Clark Kerr to call him, hyperbolically, “the chief guru of the FSM.” Berkeley, The New Student Revolt recommends itself to all those interested in the history of protest and the left in this country, but especially, I think, to the young radicals and socialists who are today immersed in the great multiracial movement against racism and police violence and for fundamental social change. Draper became a Trotskyist in the 30s. He was part of the tendency led by Max Shachtman that split from the Trotskyists in 1940 in a dispute over the nature of the Soviet Union and formed the Workers Party. The group, which changed its name to the Independent Socialist League (ISL) in 1949, stood for what it called the Third Camp, in opposition to both capitalism and the “bureaucratic collectivism” of the Soviet Bloc and Communist China. -
Date: To: September 22, 1 997 Mr Ian Johnston©
22-SEP-1997 16:36 NOBELSTIFTELSEN 4& 8 6603847 SID 01 NOBELSTIFTELSEN The Nobel Foundation TELEFAX Date: September 22, 1 997 To: Mr Ian Johnston© Company: Executive Office of the Secretary-General Fax no: 0091-2129633511 From: The Nobel Foundation Total number of pages: olO MESSAGE DearMrJohnstone, With reference to your fax and to our telephone conversation, I am enclosing the address list of all Nobel Prize laureates. Yours sincerely, Ingr BergstrSm Mailing address: Bos StU S-102 45 Stockholm. Sweden Strat itddrtSMi Suircfatan 14 Teleptelrtts: (-MB S) 663 » 20 Fsuc (*-«>!) «W Jg 47 22-SEP-1997 16:36 NOBELSTIFTELSEN 46 B S603847 SID 02 22-SEP-1997 16:35 NOBELSTIFTELSEN 46 8 6603847 SID 03 Professor Willis E, Lamb Jr Prof. Aleksandre M. Prokhorov Dr. Leo EsaJki 848 North Norris Avenue Russian Academy of Sciences University of Tsukuba TUCSON, AZ 857 19 Leninskii Prospect 14 Tsukuba USA MSOCOWV71 Ibaraki Ru s s I a 305 Japan 59* c>io Dr. Tsung Dao Lee Professor Hans A. Bethe Professor Antony Hewlsh Department of Physics Cornell University Cavendish Laboratory Columbia University ITHACA, NY 14853 University of Cambridge 538 West I20th Street USA CAMBRIDGE CB3 OHE NEW YORK, NY 10027 England USA S96 014 S ' Dr. Chen Ning Yang Professor Murray Gell-Mann ^ Professor Aage Bohr The Institute for Department of Physics Niels Bohr Institutet Theoretical Physics California Institute of Technology Blegdamsvej 17 State University of New York PASADENA, CA91125 DK-2100 KOPENHAMN 0 STONY BROOK, NY 11794 USA D anni ark USA 595 600 613 Professor Owen Chamberlain Professor Louis Neel ' Professor Ben Mottelson 6068 Margarldo Drive Membre de rinstitute Nordita OAKLAND, CA 946 IS 15 Rue Marcel-Allegot Blegdamsvej 17 USA F-92190 MEUDON-BELLEVUE DK-2100 KOPENHAMN 0 Frankrike D an m ar k 599 615 Professor Donald A. -
Melvin Calvin
M ELVIN C A L V I N The path of carbon in photosynthesis Nobel Lecture, December 11, 1961 Introduction It is almost sixty years since Emil Fischer was describing on a platform such as this one, some of the work which led to the basic knowledge of the struc- ture of glucose and its relatives 1 . Today we will be concerned with a de- scription of the experiments which have led to a knowledge of the principal reactions by which those carbohydrate structures are created by photo- synthetic organisms from carbon dioxide and water, using the energy of light. The speculations on the way in which carbohydrate was built from carbon dioxide began not long after the recognition of the basic reaction and were carried forward first by Justus von Liebig and then by Adolf von Baeyer and, finally, by Richard Willstätter and Arthur Stall into this century. Actually, the route by which animal organisms performed the reverse reaction, that is, the combustion of carbohydrate to carbon dioxide and water with the utili- zation of the energy resulting from this combination, turned out to be the first one to be successfully mapped, primarily by Otto Meyerhof 2 and Hans Krebs 3. Our own interest in the basic process of solar energy conversion by green plants, which is represented by the overall reaction began some time in the years between 1935 and 1937, during my post- doctoral studies with Professor Michael Polanyi at Manchester. It was there I first became conscious of the remarkable properties of coordinated metal compounds, particularly metalloporphyrins as represented by heme and chlorophyll. -
Cshe.6.16 University of California, Berkeley
Research & Occasional Paper Series: CSHE.6.16 UNIVERSITY OF CALIFORNIA, BERKELEY http://cshe.berkeley.edu/ THE ONE-UNIVERSITY IDEA AND ITS FUTURES June 2016 Patricia A. Pelfrey UC Berkeley Copyright 2016 Patricia A. Pelfrey, all rights reserved. ABSTRACT The University of California, the nation’s first multicampus system, is unique in its central organizing principle, known as the one- university idea. Its premise is simple: that a large and decentralized system of campuses, which share the same mission but differ in size, interests, aspirations, and stage of development, can nevertheless be governed as a single university. Long regarded as a major structural reason for the UC system’s rise to pre-eminence among public research universities, the one- university model has been a unifying administrative and cultural ethos within UC for more than 80 years. Today it represents a striking counterpoint to current theories of multicampus university governance that argue for ever-greater campus independence and hybrid public-private models to address the serious financial plight facing public research universities. Does it have a future in the era of disruptive innovation? The story of its origin and evolution suggests several points about governance and organizational reform in universities. Institutional redesign is rarely an impartial contest among rational alternatives. It is the product not only of financial and other external pressures but also of institutional conflicts, personal rivalries, temporary interests, and the irresistible urge to rectify the mistakes of predecessors. Actual reform in universities comes with a history, and UC’s experience offers its own context for today’s national debate about multicampus systems and new paradigms of university governance and organization. -
Plant- Physiology and the PLANT CELL on the ASPP Homepage Click on "Publications" Click Onjournal Title
THE NEWSLETTER OF THE AMERICAN SOCIETY OF PLANT PHYSIOLOGISTS Volume 24, Number 2 March/April 1997 Preparing for a Record Turnout ill Vancouver lant Biology '97: A View from the Pacific Rim, submitted from anywhere in the world. Second, it Pthrough a combination of factors and a lot of made the sorting and planning process for the hard work, has culminated in what promises to be program committee go much more smoothly than one of the largest and most international plant usual. Third, it will result in an on-line searchable science meetings ever. The American Society of abstract database and meeting program that will be Plant Physiologists and the Canadian Society of made accessible through ASPP's web page in April. Plant Physiologists, along with the help of the And last, a more complete and cohesive abstract Japanese Society of Plant Physiologists and the supplement and printed program will be the final Australian Society of Plant Physiologists, Inc., and result. the more widespread use of the Internet, have announced the meeting all over the world. Informa Oral and Poster Scheduling tion about the meeting has been available on ASPP's web page since last summer, and numerous l A]hiIe we are pleased and excited about the III messages about the conference have been posted to unprecedented number of abstract submis VV pertinent plant science newsgroups. Full-color sions for Plant Biology '97, the program committee advertisements have been displayed in the journals was also faced with a new set of scheduling or other advertising modes sponsored by all four challenges. -
Documenting the Biotechnology Industry in the San Francisco Bay Area
Documenting the Biotechnology Industry In the San Francisco Bay Area Robin L. Chandler Head, Archives and Special Collections UCSF Library and Center for Knowledge Management 1997 1 Table of Contents Project Goals……………………………………………………………………….p. 3 Participants Interviewed………………………………………………………….p. 4 I. Documenting Biotechnology in the San Francisco Bay Area……………..p. 5 The Emergence of An Industry Developments at the University of California since the mid-1970s Developments in Biotech Companies since mid-1970s Collaborations between Universities and Biotech Companies University Training Programs Preparing Students for Careers in the Biotechnology Industry II. Appraisal Guidelines for Records Generated by Scientists in the University and the Biotechnology Industry………………………. p. 33 Why Preserve the Records of Biotechnology? Research Records to Preserve Records Management at the University of California Records Keeping at Biotech Companies III. Collecting and Preserving Records in Biotechnology…………………….p. 48 Potential Users of Biotechnology Archives Approaches to Documenting the Field of Biotechnology Project Recommendations 2 Project Goals The University of California, San Francisco (UCSF) Library & Center for Knowledge Management and the Bancroft Library at the University of California, Berkeley (UCB) are collaborating in a year-long project beginning in December 1996 to document the impact of biotechnology in the Bay Area. The collaborative effort is focused upon the development of an archival collecting model for the field of biotechnology to acquire original papers, manuscripts and records from selected individuals, organizations and corporations as well as coordinating with the effort to capture oral history interviews with many biotechnology pioneers. This project combines the strengths of the existing UCSF Biotechnology Archives and the UCB Program in the History of the Biological Sciences and Biotechnology and will contribute to an overall picture of the growth and impact of biotechnology in the Bay Area. -
Profiles, Pathways and Dreams: from Naïveté to the Hist Award
Bull. Hist. Chem., VOLUME 43, Number 2 (2018) 45 PROFILES, PATHWAYS AND DREAMS: FROM NAÏVETÉ TO THE HIST AWARD Jeffrey I. Seeman, Department of Chemistry, University of Richmond, Richmond, VA, USA, 23173, [email protected] Editor’s Note the Bulletin for the History of Chemistry publishes that presentation. Seeman, a strong supporter of the Bulletin, Jeffrey I. Seeman of the University of Richmond preferred to be in the audience rather than lecture at the is the 2017 recipient of the HIST Award for Outstand- symposium. Nonetheless, he happily provided an award ing Lifetime Achievement in the History of Chemistry, manuscript for the Bulletin. He consulted several col- awarded annually by the American Chemical Society leagues on an appropriate topic for his award paper, and (ACS) Division of the History of Chemistry (HIST). This the following article is the result. In what follows, readers international award has been granted since 1956 under will get to know several of the 20th century’s prominent sequential sponsorships by the Dexter Chemical Com- organic chemists as well as Seeman. pany, the Sidney M. Edelstein Family and the Chemical Heritage Foundation, and HIST. Among the highlights —Carmen Giunta, Editor of Seeman’s work in history of chemistry are numerous articles on the history of 20th-century organic chemistry, Introduction service on the executive committee of HIST including a term as chair, founding and administering HIST’s Cita- Work like you don’t need the money. Love like tion for Chemical Breakthrough Award program, the pro- you’ve never been hurt. Dance like nobody’s watching. -
Spring 1965 an Analytic and Autobiographical Account (2008)
one Spring 1965 An Analytic and Autobiographical Account (2008) in january 1965, in the wake of the turbulent Free Speech Movement on the Berkeley campus and the demise of its chancellor, Edward Strong, the new acting chancellor, Martin Meyerson, asked me to join his staff as a special assistant in the area of student political activity. This was the hottest seat in the chancellor’s offi ce at that moment, given the political fragility of the campus. I served eight months in that capacity until a new chancellor, Roger Heyns, was appointed and I took a scheduled sabbatical leave. Those months were a tense and uncertain period that resulted in an unsteady but palpable restoration of authority on the Berkeley campus and a few steps toward campus “normalcy.” They also constituted a period of rapid and mandatory political learning on my part and one of the most demanding seasons of my life. Over the years many colleagues have asked me to write about this important transitional period, both because it has received less attention than the historic Free Speech Movement days of late 1964 and because I had an “insider’s” point of view; now, in 2008, I have fi nally acceded to those requests. I have returned to the archives of the chancellor’s offi ce, to accounts of the events in the press, and to my personal recollections. The staff of the Bancroft Library were very helpful in supplying materials relevant to the Meyerson administration from the fi les of the chancellor’s offi ce. I also benefi ted from the research assistance of Ziza Delgado and Catherine Shepard-Haier. -
Top of Page Interview Information--Different Title
Regional Oral History Office University of California The Bancroft Library Berkeley, California Howard Schachman UC Berkeley Professor of Molecular Biology: On the Loyalty Oath Controversy, the Free Speech Movement, and Freedom in Scientific Research Interviews conducted by Ann Lage in 2000-2001 Copyright © 2007 by The Regents of the University of California Since 1954 the Regional Oral History Office has been interviewing leading participants in or well-placed witnesses to major events in the development of Northern California, the West, and the nation. Oral History is a method of collecting historical information through tape-recorded interviews between a narrator with firsthand knowledge of historically significant events and a well-informed interviewer, with the goal of preserving substantive additions to the historical record. The tape recording is transcribed, lightly edited for continuity and clarity, and reviewed by the interviewee. The corrected manuscript is bound with photographs and illustrative materials and placed in The Bancroft Library at the University of California, Berkeley, and in other research collections for scholarly use. Because it is primary material, oral history is not intended to present the final, verified, or complete narrative of events. It is a spoken account, offered by the interviewee in response to questioning, and as such it is reflective, partisan, deeply involved, and irreplaceable. ********************************* All uses of this manuscript are covered by a legal agreement between The Regents of the University of California and Howard Schachman, dated April 26, 2007. The manuscript is thereby made available for research purposes. All literary rights in the manuscript, including the right to publish, are reserved to The Bancroft Library of the University of California, Berkeley. -
Deciphering the Benson-Bassham-Calvin Cycle
Deciphering the Benson-Bassham-Calvin Cycle 1. A technological revolution for deciphering the cycle Figure 1. Discoverers of the photosynthetic carbon reduction cycle (from left to right): James A. Bassham, Andrew A. Benson and Melvin Calvin. Photo presented to Karl Biel by Andrew A. Benson (September 9, 1988). [Source: Reprinted with permission of Karl Biel] Around 1945, the american chemists A.A. Benson, J.A. Bassham and M. Calvin [1] (Figure 1) tackled the task of identifying the first carbon-containing product of photosynthesis that had escaped all scientific investigation. After the World War II, these researchers had just acquired two new important technological allies in Berkeley, California: ● a radioactive tracer, 14C, which had just been isolated by S. Ruben and M. Kamen in 1941 [2], ● new techniques for the chromatographic separation of the carbon-containing compounds from metabolism, developed a few years earlier in England by R. Martin and A. Synge. [3] These two tools will allow Dr. Calvin and his co-workers to identify the path taken by carbon during the various biochemical reactions for assimilation of the photosynthetic carbon. Encyclopédie de l'environnement 1/4 Généré le 26/09/2021 Figure 2. Diagram of the apparatus used to monitor the incorporation of photosynthetic carbon into the products of photosynthesis . In the centre: device used for the study of CO2 fixation by unicellular algae. [Source Photo © Ernest O. Lawrence, Berkeley National Laboratory, Photography and Digital Imaging Services: previously unpublished, Biochemistry & Molecular Biology of Plants. B.B. Buchanan, W. Gruissem & R.L. Jones. American Society of Plant Physiologists, Rockville, MD.