DOCSLIB.ORG

Cardinal Health Anatomic Pathology Catalog

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Cardinal Health Anatomic Pathology Catalog Laboratory Products Anatomic Pathology Laboratory products for your Anatomic Pathology needs. Better solutions for your laboratory. Your challenges are where we start. We then provide your lab with options and flexibility, saving you time and money. Solutions are tailored, like this catalog, which was designed especially for the Anatomic Pathology Lab. When analyzing at the tissue level, precision is a must. We’re here to provide you with the tools you need to do your job more effectively. The Cardinal Health laboratory product portfolio features items designed for all disciplines, from Hematology to Histology. Thousands of supplies from hundreds of leading manufacturers. Our dedicated sales professionals can recommend the best products at the best prices for your lab’s unique needs. Saving you valuable time. Count on Cardinal Health to help you navigate challenges and discover solutions. Allowing you to focus on keeping your lab running smoothly. To hear more about how we can support your lab, contact your Cardinal Health sales representative or call 800.964.5227. Table of Contents Cytology Brushes .......................................................................................................2 Centrifuges ................................................................................................3 Centrifuge Accessories .....................................................................4-6 Fixatives ......................................................................................................7 Pap Smear Kits and Supplies ..............................................................8 Digital Microscope ...........................................................................9-10 Embedding Cassettes ............................................................................................11-35 Embedding Machines and Accessories .................................36-37 Molds and Supplies .......................................................................38-40 Paraffin and Accessories ..............................................................41-44 Specimen Collection Grossing and Autopsy Prefilled Containers .......................................................................85-90 Autopsy Blades and Knives ...............................................................45 Specimen Bags ............................................................................... 91-94 Cutting and Dissection Boards ....................................................... 46 Specimen Containers ...................................................................95-97 Grossing Accessories ....................................................................46-48 Grossing Stations ...........................................................................49-50 Staining and Coverslipping Scalpels and Blades .......................................................................50-51 Coverslips/Cover Glasses ..........................................................98-101 Scissors......................................................................................................51 Coverslipping ..............................................................................101-104 Coverslippers and Accessories ..............................................105-106 Labeling and Storage Slides............................................................................................... 107-124 Labelers and Software ................................................................. 52-53 Slide Accessories ................................................................................ 125 Mailers and Shippers .................................................................... 53-55 Slide Dryers .......................................................................................... 125 Slide Boxes ........................................................................................56-58 Stainers and Accessories ................................................................. 126 Slide Folders ....................................................................................59-60 Staining Dishes, Jars and Racks ............................................ 127-130 Storage Systems .............................................................................60-67 Stains .............................................................................................. 131-143 Reagents and Chemicals Tissue Processing Reagents and Chemicals .............................................................68-69 Biopsy Bags/Capsules/Pads ...................................................144-145 Absorbent and Disposal Supplies ........................................... 70-71 Biopsy Papers ...................................................................................... 146 Frequently Used Reagents ..........................................................72-75 Slide Marking Pens and Pencils ............................................146-147 Specimen Processing Gel................................................................ 147 Sectioning Tissue Processors and Accessories ......................................148-149 Blades ................................................................................................. 76-78 Waste Management .......................................................................... 149 Microtomes/Cryostats and Accessories ................................79-82 Tissue Floatation Baths and Workstations ...........................83-84 Product Index ................................................................................150-166 Slide Warmer ......................................................................................... 84 Wrinkle Remover .................................................................................. 84 Catalog Number Index ........................................................... 167-181 Terms and Conditions of Sale .................................................... 182 To order, call: 800.964.5227 cardinalhealth.com 1 Cytology Brushes Cervex-Brush™ Pap Smear Specimen Collection Devices ANDWIN SCIENTIFIC - This nonsterile, broom-style brush collects all essential cells for tracing the early stages of cervical cancer. The bristles collect endocervical, Cytology ectocervical and T-zone cells. The soft, flexible bristles reduce the risk of injury during examination. Cat. No. Mfr. No. Description Qty. 893010 893010 Specimen collection device 50/bg, 20 bg/cs Cervix Brush Cytology Brushes LEICA BIOSYSTEMS - The Cervix Brush, from Rovers Medical Devices BV, ANDWIN SCIENTIFIC - Designed specifically for provides a clear and accurate sample for the early detection of cervical the collection of endocervical specimens, these cancer. It is made of polythylene and has a total length of 200 mm. The cytology brushes are perfect for Pap smear top portion uses a soft, flexible brush to obtain cell samples, while the and Chlamydia procedures. They are 70% more shape allows the top edges to follow the contours of the cervix. The effective than swabs for collecting intact cells. detachable head makes it ideal use for Liquid Based Cytology systems. The brushes are available in two sizes. Cat. No. Mfr. No. Description Qty. Cat. No. Mfr. No. Description Qty. L3801990 3801990 Cervix brush - 200 mm 25/bg S7783-20 892010-C500 5 in. 100/bg, 5 bg/cs S7783-21 892030-C500 8 in. 100/bg, 5 bg/cs C-E Brushes Histobrush® Cytology Brushes LEICA BIOSYSTEMS - The C-E Brush is PURITAN MEDICAL PRODUCTS - These tapered, soft cytology brushes specifically designed to gently collect an are gentle on patients. They feature a nylon tip and polystyrene shaft. adequate amount of endocervical material Sterile brush is individually-wrapped. for a more accurate pap smear diagnosis. Cat. No. Mfr. No. Description Qty. The bristle head is barrel shaped (as opposed 2199 2199 Nonsterile brush - 7 in. 100/bx, 10 bx/cs to cone shaped). The longer bristles at the 2188 2188 Nonsterile brush - 8 in. 100/bx, 10 bx/cs tip cause less discomfort and bleeding to the patients, while allowing for a greater 25-2199 25-2199 Sterile brush - 7 in. 100/bx, 10 bx/cs collection surface when harvesting cells from the squamal columnar junction. Cat. No. Mfr. No. Description Qty. Rovers® Cervex Brushes L3801970 3801970 6 in. brush 100/bg PURITAN MEDICAL PRODUCTS - Use this 8 in. L3801975 3801975 6 in. brush 500/bx brush for cell collection from the endocervical L3801980 3801980 7½ in. brush 100/bg T-zone in Pap smears. It also can be used with thin L3801981 3801981 7½ in. brush 500/bx prep technology and glass slides. The brush has a polyethylene shaft and convenient removable tip. Cat. No. Mfr. No. Description Qty. Snap-Off C-E Brushes HW2195 2195 Endocervix brush - 8 in. 25/bg, 35 bg/cs LEICA BIOSYSTEMS - The Snap-Off C-E Brush has been produced to work with today’s liquid base cytology automated systems and comes in a 7½ in. length. The snap off 1.75 portion is removable from the rest of the Rovers® EndoCervex-Brush® stem. This portion can then easily be dropped PURITAN MEDICAL PRODUCTS - The EndoCervex-Brush® is designed to into a preparation jar for transport. optimize cellular yield in Pap smear specimen collection. This nonsterile one-piece brush features 600 separate collection bristles for the Cat. No. Mfr. No. Description Qty. simultaneous collection of cellular material. The stiff yet flexible bristle L3801987 3801987 7½ in. brush 50/bg head has a protective tip to enhance the collection process. A safety
Load more

Recommended publications
  • Non-Commercial Use Only
    Veins and Lymphatics 2012; volume 1:e6 Ulcerated hemosiderinic three months previous to this therapy. Significant improvement in these injuries, Correspondence: Eugenio Brizzio and Alberto dyschromia and iron deposits with a reduction in the dimensions of the Lazarowski, San Martín 965, 1st floor (Zip code within lower limbs treated brown spot (9 of 9) at Day 90, and complete 1004) Buenos Aires, Argentina. with a topical application scarring with a closure time ranging from 15 Tel. +54.11.4311.5559. to 180 days (7 of 9) were observed. The use of E-mail: [email protected]; of biological chelator [email protected]; topical lactoferrin is a non-invasive therapeu- [email protected]; tic tool that favors clearance of hemosiderinic 1 2 [email protected] Eugenio Brizzio, Marcelo Castro, dyschromia and scarring of the ulcer. The 3 2 Marina Narbaitz, Natalia Borda, success of this study was not influenced Key words: ulcerated haemosiderinic dyschro- Claudio Carbia,2 Laura Correa,4 either by the hemochromatosis genetics or mia, liposomal Lactoferrin, scarring, hemo- Roberto Mengarelli,5 Amalia Merelli,2 the iron metabolism profile observed. siderin-ferritin. Valeria Brizzio,2 Maria Sosa,6 Acknowledgments: the authors would like to Biagio Biancardi,7 Alberto Lazarowski2 thank P. Girimonte for her assistance with the statistical analysis of the results. We also wish to Introduction thank the patients who made this study possible. 1International Group of Compression and Conference presentation: part of the present Argentina Medical Association, Buenos Chronic venous insufficiency (CVI) is one of study has been presented at the following con- 2 Aires, Argentina; Department of Clinical the most significant health problems in devel- gresses: i) XX Argentine Congress of Hematology, Biochemistry, Institute of oped countries.
    [Show full text]
  • New York State Thoroughbred Breeding and Development Fund Corporation
    NEW YORK STATE THOROUGHBRED BREEDING AND DEVELOPMENT FUND CORPORATION Report for the Year 2008 NEW YORK STATE THOROUGHBRED BREEDING AND DEVELOPMENT FUND CORPORATION SARATOGA SPA STATE PARK 19 ROOSEVELT DRIVE-SUITE 250 SARATOGA SPRINGS, NY 12866 Since 1973 PHONE (518) 580-0100 FAX (518) 580-0500 WEB SITE http://www.nybreds.com DIRECTORS EXECUTIVE DIRECTOR John D. Sabini, Chairman Martin G. Kinsella and Chairman of the NYS Racing & Wagering Board Patrick Hooker, Commissioner NYS Dept. Of Agriculture and Markets COMPTROLLER John A. Tesiero, Jr., Chairman William D. McCabe, Jr. NYS Racing Commission Harry D. Snyder, Commissioner REGISTRAR NYS Racing Commission Joseph G. McMahon, Member Barbara C. Devine Phillip Trowbridge, Member William B. Wilmot, DVM, Member Howard C. Nolan, Jr., Member WEBSITE & ADVERTISING Edward F. Kelly, Member COORDINATOR James Zito June 2009 To: The Honorable David A. Paterson and Members of the New York State Legislature As I present this annual report for 2008 on behalf of the New York State Thoroughbred Breeding and Development Fund Board of Directors, having just been installed as Chairman in the past month, I wish to reflect on the profound loss the New York racing community experienced in October 2008 with the passing of Lorraine Power Tharp, who so ably served the Fund as its Chairwoman. Her dedication to the Fund was consistent with her lifetime of tireless commitment to a variety of civic and professional organizations here in New York. She will long be remembered not only as a role model for women involved in the practice of law but also as a forceful advocate for the humane treatment of all animals.
    [Show full text]
  • Simple Technique to Identify Haemosiderin in Immunoperoxidase Stained Sections
    J Clin Pathol: first published as 10.1136/jcp.37.10.1190 on 1 October 1984. Downloaded from 1190 Technical methods Phosphate buffer at pH 8*0 gave the sharpest 2 Rozenszajn L, Leibovich M, Shoham D, Epstein J. The esterase staining reactions, although there was little differ- activity in megaloblasts, leukaemic and normal haemopoietic cells. Br J Haematol 1968; 14:605-19. ence at pH 7-0 or pH 7-5. As the buffer pH was 3Hayhoe FGJ, Quaglino D. Haematological cytochemistry. Edin- increased above pH 8-0 staining with both substrates burgh: Churchill Livingstone, 1980. became progressively weaker, especially above pH 4Li CY, Lam KW, Yam LT. Esterases in human leucocytes. J 9.0. Below pH 7-0 staining with a-naphthyl butyrate Histochem Cytochem 1973;21:1-12. Yam LT, Li CY, Crosby WH. Cytochemical identification of became weaker, and below pH 5*0 staining with monocytes and granulocytes. Am J Clin Pathol 1971;55:283- naphthol AS-D chloroacetate began to disappear. 90. 6 Armitage RJ, Linch DC, Worman CP, Cawley JC. The morphol- This work was supported by a Medical Research ogy and cytochemistry of human T-cell subpopulations defined by monoclonal antibodies and Fc receptors. Br J Haematol Council project grant. I thank Professor FGJ 1983;51:605-13. Hayhoe for valuable advice. References Requests for reprints to: Dr DM Swirsky, Department of Gomori G. Chloroacyl esters as histochemical substrates. J His- Haematological Medicine, University Clinical School, Hills tochem Cytochem 1953;1:469-70. Road, Cambridge CB2 2QL, England. Simple technique to identify identification of the two compounds on the same haemosiderin in slide.
    [Show full text]
  • The Core-Microtome a New Tool for Surface Preparation on Cores
    ARTICLE IN PRESS Dendrochronologia 28 (2010) 85–92 www.elsevier.de/dendro TECHNICAL NOTE The core-microtome: A new tool for surface preparation on cores and time series analysis of varying cell parameters Holger Ga¨rtnerÃ, Daniel Nievergelt Swiss Federal Research Institute WSL, Dendro Sciences Unit, Zu¨rcherstrasse 111, 8903 Birmensdorf, Switzerland Received 3 July 2009; accepted 25 September 2009 Abstract A microtome designed for the surface preparation of entire increment cores allows cutting plane surfaces on cores up to a length of 40 cm. Compared to the common sanding procedure, the wood cells of the annual rings remain open, not filled with swarf, and the cell walls are smooth and hence clearly visible. This article aims at describing the functionality of the microtome and the procedures needed for an accurate surface preparation to achieve a good contrast for subsequent image analysis. Possible applications for a more detailed analysis of variations in the tracheid structure of conifers and vessel sizes of oak are presented, which can be included in time series analyses. & 2009 Elsevier GmbH. All rights reserved. Keywords: Dendroecology; Wood anatomy; Increment cores; Preparation techniques Introduction on macroscopic analysis, e.g., by measuring ring-width variations or inter-annual density fluctuations. This is also Short-term as well as long-term changes of environ- true for isotope analysis. Even though the rings are split in mental conditions do have a distinct impact on the various tangentially oriented thin sections for subsequent development of trees and shrubs (Schweingruber et al., isotopic analyses, the detailed anatomical structure which 2006). The effects of these changes are archived in the rings has to be analyzed microscopically is not focused.
    [Show full text]
  • Growth Response of Whitebark Pine (Pinus Albicaulis) Regeneration to Thinning and Prescribed Burn Release Treatments
    University of Montana ScholarWorks at University of Montana Graduate Student Theses, Dissertations, & Professional Papers Graduate School 2017 GROWTH RESPONSE OF WHITEBARK PINE (PINUS ALBICAULIS) REGENERATION TO THINNING AND PRESCRIBED BURN RELEASE TREATMENTS Molly L. McClintock Retzlaff Follow this and additional works at: https://scholarworks.umt.edu/etd Part of the Forest Management Commons Let us know how access to this document benefits ou.y Recommended Citation Retzlaff, Molly L. McClintock, "GROWTH RESPONSE OF WHITEBARK PINE (PINUS ALBICAULIS) REGENERATION TO THINNING AND PRESCRIBED BURN RELEASE TREATMENTS" (2017). Graduate Student Theses, Dissertations, & Professional Papers. 11094. https://scholarworks.umt.edu/etd/11094 This Thesis is brought to you for free and open access by the Graduate School at ScholarWorks at University of Montana. It has been accepted for inclusion in Graduate Student Theses, Dissertations, & Professional Papers by an authorized administrator of ScholarWorks at University of Montana. For more information, please contact [email protected]. GROWTH RESPONSE OF WHITEBARK PINE (PINUS ALBICAULIS) REGENERATION TO THINNING AND PRESCRIBED BURN RELEASE TREATMENTS By MOLLY LINDEN MCCLINTOCK RETZLAFF Bachelor of Arts, University of Montana, Missoula, Montana, 2012 Thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Forestry The University of Montana Missoula, MT December 2017 Approved by: Dr. Scott Whittenburg, Dean Graduate School Dr. David Affleck, Chair Department of Forest Management Dr. John Goodburn Department of Forest Management Dr. Sharon Hood USDA Forest Service Rocky Mountain Research Station © COPYRIGHT by Molly Linden McClintock Retzlaff 2017 All Rights Reserved ii Retzlaff, Molly, M.S., Winter 2017 Forestry Growth response of Whitebark pine (Pinus albicaulis) regeneration to thinning and prescribed burn release treatments Chairperson: Dr.
    [Show full text]
  • Custom Engineered Tissue Culture Molds from Laser-Etched Masters
    Journal of Visualized Experiments www.jove.com Video Article Custom Engineered Tissue Culture Molds from Laser-etched Masters Nicholas J. Kaiser1, Fabiola Munarin1, Kareen L.K. Coulombe1 1 Center for Biomedical Engineering,, Brown University Correspondence to: Kareen L.K. Coulombe at [email protected] URL: https://www.jove.com/video/57239 DOI: doi:10.3791/57239 Keywords: Bioengineering, Issue 135, Tissue engineering, laser etching, replica molding, contractile mechanics, cardiac regeneration, hydrogels, drug delivery, materials science. Date Published: 5/21/2018 Citation: Kaiser, N.J., Munarin, F., Coulombe, K.L. Custom Engineered Tissue Culture Molds from Laser-etched Masters. J. Vis. Exp. (135), e57239, doi:10.3791/57239 (2018). Abstract As the field of tissue engineering has continued to mature, there has been increased interest in a wide range of tissue parameters, including tissue shape. Manipulating tissue shape on the micrometer to centimeter scale can direct cell alignment, alter effective mechanical properties, and address limitations related to nutrient diffusion. In addition, the vessel in which a tissue is prepared can impart mechanical constraints on the tissue, resulting in stress fields that can further influence both the cell and matrix structure. Shaped tissues with highly reproducible dimensions also have utility for in vitro assays in which sample dimensions are critical, such as whole tissue mechanical analysis. This manuscript describes an alternative fabrication method utilizing negative master molds prepared from laser etched acrylic: these molds perform well with polydimethylsiloxane (PDMS), permit designs with dimensions on the centimeter scale and feature sizes smaller than 25 µm, and can be rapidly designed and fabricated at a low cost and with minimal expertise.
    [Show full text]
  • Microtome: Histopathology Day Book Based on a Microcomputer System
    J Clin Pathol: first published as 10.1136/jcp.38.10.1106 on 1 October 1985. Downloaded from J Clin Pathol 1985;38:1106-1113 Microtome: histopathology day book based on a microcomputer system D ROBERTS-JONES, J McCLURE From the Department ofHistopathology, University Hospital ofSouth Manchester, Manchester SUMMARY The development of a histopathology day book based on a microcomputer is described. The system has the capacity to search on file records for details of previous specimens from current patients. It also possesses a SNOP/SNOMED input and search system that can aggregate data for analytical and other purposes. The system is relatively inexpensive and is user friendly. It has been developed within and is exclusively devoted to the requirements of a histopathology department and is designed to permit expansion to a multiuser system. The acquisition, storage, and retrieval of informa- gynaecological cytopathology) to a busy major tion are important functions of any pathology teaching hospital and receives some 12 000 speci- laboratory. In haematology, biochemistry, and (to a mens (excluding necropsy material) every year. lesser extent) microbiology laboratories results are Therefore, although initially satisfactory, in time the largely in the form of numerical data, and for several archive became oversized and somewhat cumber-copyright. years computers have been used to accumulate, some, especially the component that dealt with data store, and manipulate these data. In histopathology retrieval. It was particularly difficult to determine computers have also been used but to a much lesser whether previous biopsy material had been received extent than in the related disciplines. Part of the from the patients whose current specimens were reason for this is the fact that histopathological being handled.
    [Show full text]
  • Leica CM3050 S Cryostat
    Leica CM3050 S Cryostat Instruction Manual Leica CM3050 S Cryostat English V11 02/2000 Always keep this manual near the instrument Read carefully prior to operating the instrument Important note Serial No: The information contained in this document rep- Year of Manufacture: resents state-of-the-art technology as well as the current state of knowledge Country of Origin: Federal Republic of Germany Leica will not assume liability for errors that might be contained in this manual, nor for acci- dental damage or damage arising from the de- livery, performance or use of this manual Therefore, no claims can be made based on the text and illustrations in this instruction manual Leica Microsystems Nussloch GmbH reserves the right to change technical specifications without notice since each of our products is subject to a policy of continuous improvement This document is protected under copyright laws Leica Microsystems Nussloch GmbH retains all rights related to this documentation Any reproduction of text and illustrations - or any parts thereof - in form of printing, photo- copying, microfiches, or other methods, includ- ing electronic systems, requires the prior writ- ten permission of Leica Microsystems Nussloch GmbH Issued by: The serial number and the year of manufacture Leica Microsystems Nussloch GmbH are specified on the nameplate at the back of Heidelberger Str 17 - 19 the instrument D-69226 Nussloch Germany Phone: +49 6224 143-0 Fax: +49 6224 143-200 Internet: http://wwwhbude © Leica Microsystems Nussloch GmbH Leica CM 3050 S
    [Show full text]
  • Gomori Prussian Blue Iron Stain Histology Staining Procedure
    2505 Parview Road ● Middleton, WI 53562-2579 ● 800-383-7799 ● www.newcomersupply.com ● [email protected] July 2016 Gomori Prussian Blue Iron Stain - Technical Memo SOLUTIONS: 500 ml 1 Liter Hydrochloric Acid 20%, Aqueous Part 12087A Part 12087B Potassium Ferrocyanide 10%, Aqueous Part 13392A Additionally Needed: Iron Control Slides Part 4320 or Iron, Animal Control Slides Part 4321 Xylene, ACS Part 1445 Alcohol, Ethyl Denatured, 100% Part 10841 Alcohol, Ethyl Denatured, 95% Part 10842 Nuclear Fast Red Stain, Kernechtrot Part 1255 Hydrochloric Acid 5%, Aqueous Part 12086 (for acid cleaning glassware) For storage requirements and expiration date refer to individual product labels. APPLICATION: PROCEDURE NOTES: Newcomer Supply Gomori Prussian Blue Iron Stain is used to detect 1. Acid clean all glassware/plasticware (12086) and rinse thoroughly loosely bound ferric iron in tissue sections, bone marrow smears and in several changes of distilled water. Cleaning glassware with blood smears. This histochemical reaction is sensitive enough to bleach is not equivalent to acid washing. demonstrate even minute amounts of iron deposits in blood cells, bone 2. Drain staining rack/slides after each step to prevent solution carry marrow, spleen and liver. over. 3. Do not allow sections to dry out at any point during staining METHOD: procedure. Fixation: Formalin 10%, Phosphate Buffered (Part 1090) 4. Wash well after Nuclear Fast Red Stain, Kernechtrot to avoid a. Chromate fixatives should be avoided cloudiness in dehydration steps. b. Fix smears per laboratory protocol 5. If using a xylene substitute, closely follow the manufacturer’s Technique: Paraffin sections cut at 5 microns or prepared smears recommendations for deparaffinization and clearing steps Solutions: All solutions are manufactured by Newcomer Supply, Inc.
    [Show full text]
  • Maccarrone-G.Pdf
    Journal of Chromatography B, 1047 (2017) 131–140 Contents lists available at ScienceDirect Journal of Chromatography B jou rnal homepage: www.elsevier.com/locate/chromb MALDI imaging mass spectrometry analysis—A new approach for protein mapping in multiple sclerosis brain lesions a,b,1 a,1 c Giuseppina Maccarrone , Sandra Nischwitz , Sören-Oliver Deininger , a d,e d Joachim Hornung , Fatima Barbara König , Christine Stadelmann , b,1 a,f,∗,1 Christoph W. Turck , Frank Weber a Max Planck Institute of Psychiatry, Kraepelinstr. 2-10, 80804 Munich, Germany b Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Germany c Bruker Daltonik GmbH, Fahrenheitstr. 4, 28359 Bremen, Germany d Institute of Neuropathology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany e Institut für Pathologie, Klinikum Kassel, Mönchebergstr. 41-43, 34125 Kassel, Germany f Medical Park Bad Camberg, Obertorstr. 100-102, 65520 Bad Camberg, Germany a r t i c l e i n f o a b s t r a c t Article history: Multiple sclerosis is a disease of the central nervous system characterized by recurrent inflammatory Received 21 February 2016 demyelinating lesions in the early disease stage. Lesion formation and mechanisms leading to lesion Accepted 1 July 2016 remyelination are not fully understood. Matrix Assisted Laser Desorption Ionisation Mass Spectrom- Available online 1 July 2016 etry imaging (MALDI–IMS) is a technology which analyses proteins and peptides in tissue, preserves their spatial localization, and generates molecular maps within the tissue section. In a pilot study we Keywords: employed MALDI imaging mass spectrometry to profile and identify peptides and proteins expressed in MALDI imaging mass spectrometry normal-appearing white matter, grey matter and multiple sclerosis brain lesions with different extents LC–ESI–MS/MS of remyelination.
    [Show full text]
  • Detection of Acute TLR-7 Agonist-Induced Hemorrhagic Myocarditis in Mice by Refined Multi-Parametric Quantitative Cardiac MRI
    bioRxiv preprint doi: https://doi.org/10.1101/502237; this version posted December 21, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. CMR imaging for hemorrhagic myocarditis in mice Baxan et al. 2018 Detection of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by refined multi-parametric quantitative cardiac MRI. Nicoleta Baxan1, Angelos Papanikolaou2, Isabelle Salles-Crawley2, Amrit Lota3, Rasheda Chowdhury2, Olivier Dubois1, Jane Branca4, Muneer G. Hasham4, Nadia Rosenthal2,4, Sanjay K. Prasad3, Lan Zhao1,2, Sian E. Harding2, Susanne Sattler2 Affiliations: 1Biological Imaging Centre, Department of Medicine, Imperial College London, London, 2National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK 3Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, London SW3 6NP, UK 4The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA Abstract BACKGROUND: Hemorrhagic myocarditis is a potentially fatal complication of excessive levels of systemic inflammation. It has been reported in viral infection, but is also possible in systemic autoimmunity. Cardiac magnetic resonance (CMR) imaging is the current gold standard for non-invasive detection of suspected inflammatory damage to the heart and changes in T1 and T2 relaxation times are commonly used to detect edema associated with immune cell infiltration and fibrosis. These measurements also form the basis of the Lake Louise Criteria, which define a framework for the CMR-based diagnosis of myocarditis. However, they do not take into account the possibility of hemorrhage leading to tissue iron deposition which strongly influences T1 and T2 measurements and may complicate interpretation based on these two parameters only.
    [Show full text]
  • Snomed Ct Dicom Subset of January 2017 Release of Snomed Ct International Edition
    SNOMED CT DICOM SUBSET OF JANUARY 2017 RELEASE OF SNOMED CT INTERNATIONAL EDITION EXHIBIT A: SNOMED CT DICOM SUBSET VERSION 1.
    [Show full text]