GeneMANIA http://www.genemania.org/print
Created on: 6 December 2012 20:34:57 Last database update: 19 July 2012 20:00:00 Application version: 3.1.1
Report of GeneMANIA search
Network image
TFAP2D DLX3
TP53 LHX2 HNRNPAB
FMOD DLX2 RB1
NRIP1
KDM5B VASN
TGFBR1 HTRA1
1.84 Functions legend Networks legend embryonic morphogenesis Co-expression query genes Physical interactions Predicted Shared protein domains
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Search parameters
Organism: H. sapiens (human)
Genes: TP63; GLI2; TGFB2; PVRL1; IRF6; TGFB3; RARA; AP-2; MSX1; JAG2; PAX9
Networks: Attributes: Co-expression: Arijs-Rutgeerts-2009 Berchtold-Cotman-2008 Bild-Nevins-2006 B Burczynski-Dorner-2006 Burington-Shaughnessy-2008 Gobble-Singer-2011 Hummel-Siebert-2006 Jones-Libermann-2005 Kang-Willman-2010 Nakayama-Hasegawa-2007 Noble-Diehl-2008 Peng-Katze-2009 Perou-Botstein-1999 Radtke-Downing-2009 Ramaswamy-Golub-2001 Raue-Trappe-2012 Rieger-Chu-2004 Toedter-Baribaud-2011 Wang-Maris-2006 Wu-Garvey-2007 Co-localization: Johnson-Shoemaker-2003 Schadt-Shoemaker-2004 Genetic interactions: BIOGRID-SMALL-SCALE-STUDIES IREF-SMALL-SCALE-STUDIES Lin-Smith-2010 Pathway: PATHWAYCOMMONS-CELL_MAP PATHWAYCOMMONS-HUMANCYC PATHWAYCOMMONS-IMID PATHWAYCOMMONS-NCI_NATURE PATHWAYCOMMONS-REACTOME Wu-Stein-2010 Physical interactions: Albers-Koegl-2005 Arbuckle-Grant-2010 BIOGRID-SMALL-SCALE-STUDIES Bandyopadhyay-Ideker-2010 Barr-Knapp-2009 Barrios-Rodiles-Wrana-2005 Behrends-Harper-2010 Behzadnia-Lührmann-2007 Benzinger-Hermeking-2005 Bouwmeester-Superti-Furga-2004 Camargo-Brandon-2007 Cannavo-Jiricny-2007 Colland-Gauthier-2004 Ewing-Figeys-2007 A Ewing-Figeys-2007 B Fenner-Prehn-2010 Glatter-Gstaiger-2009 Goehler-Wanker-2004 Goudreault-Gingras-2009 Hutchins-Peters-2010 IREF-BIND IREF-BIND-TRANSLATION IREF-CORUM IREF-DIP IREF-GRID IREF-HPRD IREF-INTACT IREF-MINT IREF-MPPI IREF-OPHID IREF-SMALL-SCALE-STUDIES Jeronimo-Coulombe-2007 Jin-Pawson-2004 Jones-MacBeath-2006 Kneissl-Grummt-2003 Lehner-Sanderson-2004 A Lehner-Sanderson-2004 B Lim-Zoghbi-2006 Markson-Sanderson-2009 McFarland-Nussbaum-2008 Meek-Piwnica-Worms-2004 Miyamoto-Sato-Yanagawa-2010 Nakayama-Ohara-2002 Newman-Keating-2003 Ramachandran-LaBaer-2004 Ravasi-Hayashizaki-2010 Rual-Vidal-2005 A Rual-Vidal-2005 B Sato-Conaway-2004 Sowa-Harper-2009 A Sowa-Harper-2009 B Stelzl-Wanker-2005 A Stelzl-Wanker-2005 B Svendsen-Harper-2009 Thalappilly-Dusetti-2008 Venkatesan-Vidal-2009 Wang-He-2008 Weinmann-Meister-2009 Wu-Li-2007 de Hoog-Mann-2004 van Wijk-Timmers-2009 Predicted: I2D-BIND-Fly2Human I2D-BIND-Mouse2Human I2D-BIND-Rat2Human I2D-BIND-Worm2Human I2D-BIND-Yeast2Human I2D-BioGRID-Fly2Human I2D-BioGRID-Mouse2Human I2D-BioGRID-Rat2Human I2D-BioGRID-Worm2Human I2D-BioGRID-Yeast2Human I2D-Chen-Pawson-2009-PiwiScreen-Mouse2Human I2D-Formstecher-Daviet-2005-Embryo-Fly2Human I2D-Formstecher-Daviet-2005-Head-Fly2Human I2D-Giot-Rothbert-2003-High-Fly2Human I2D-Giot-Rothbert-2003-Low-Fly2Human I2D-INNATEDB-Mouse2Human I2D-IntAct-Fly2Human I2D-IntAct-Mouse2Human I2D-IntAct-Rat2Human I2D-IntAct-Worm2Human I2D-IntAct-Yeast2Human I2D-Krogan-Greenblatt-2006-Core-Yeast2Human I2D-Krogan-Greenblatt-2006-NonCore-Yeast2Human I2D-Li-Vidal-2004-CE-DATA-Worm2Human I2D-Li-Vidal-2004-CORE-1-Worm2Human I2D-Li-Vidal-2004-CORE-2-Worm2Human I2D-Li-Vidal-2004-interolog-Worm2Human I2D-Li-Vidal-2004-literature-Worm2Human I2D-Li-Vidal-2004-non-core-Worm2Human I2D-MGI-Mouse2Human I2D-MINT-Fly2Human I2D-MINT-Mouse2Human I2D-MINT-Rat2Human I2D-MINT-Worm2Human I2D-MINT-Yeast2Human I2D-MIPS-Yeast2Human I2D-Manual-Mouse2Human I2D-Manual-Rat2Human I2D-Ptacek-Snyder-2005-Yeast2Human I2D-Stanyon-Finley-2004-CellCycle-Fly2Human I2D-Tarassov-PCA-Yeast2Human I2D-Tewari-Vidal-2004-TGFb-Worm2Human I2D-Wang-Orkin-2006-EScmplx-Mouse2Human I2D-Wang-Orkin-2006-EScmplxIP-Mouse2Human I2D-Wang-Orkin-2006-EScmplxlow-Mouse2Human I2D-Yu-Vidal-2008-GoldStd-Yeast2Human I2D-vonMering-Bork-2002-High-Yeast2Human I2D-vonMering-Bork-2002-Low-Yeast2Human I2D-vonMering-Bork-2002-Medium-Yeast2Human Stuart-Kim-2003 Shared protein domains: INTERPRO PFAM
Network weighting: Automatically selected weighting method (Assigned based on query genes)
Number of gene results: 20
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Networks
Physical interactions 72.07 % IREF-CORUM 61.70 % Source: Direct interaction with 637 interactions from iRefIndex
IREF-HPRD 6.58 % Source: Direct interaction with 36,755 interactions from iRefIndex
IREF-SMALL-SCALE-STUDIES 3.79 % Source: Direct interaction with 41,955 interactions from iRefIndex
Co-expression 12.09 % Burczynski-Dorner-2006 3.25 % Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn . Source: Pearson correlation with 419,356 interactions from GEO
Burington-Shaughnessy-2008 3.17 % Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res . Source: Pearson correlation with 266,464 interactions from GEO Tags: transcription factors; time series; cancer; chemotherapy
Hummel-Siebert-2006 2.65 % A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med . Source: Pearson correlation with 466,765 interactions from GEO Tags: cancer
Wu-Garvey-2007 1.43 % The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine . Source: Pearson correlation with 223,988 interactions from GEO Tags: transcription factors; muscle; cultured cells
Rieger-Chu-2004 0.82 % Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A . Source: Pearson correlation with 220,846 interactions from GEO Tags: cultured cells; cell line
Wang-Maris-2006 0.77 % Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res . Source: Pearson correlation with 231,830 interactions from GEO Tags: transcription factors; cancer
Shared protein domains 8.73 % INTERPRO 8.73 % Source: Pearson correlation with 488,822 interactions from InterPro
Predicted 7.11 % I2D-BIND-Mouse2Human 7.11 % BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics . Note: I2D predictions of protein protein interactions using BIND Mus musculus data
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Source: Direct interaction with 1,198 interactions from I2D
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Attributes
Attribute Gene
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Genes
IRF6 interferon regulatory factor 6 [Source:HGNC Symbol;Acc:6121] Functions: 1 5
91
Synonyms: ENSG00000117595; ENSP00000355988; ENSP00000403855; ENSP00000440532; 3664; IRF6; NP_001193625; NP_006138; NM_001206696; NM_006147; LPS; OFC6; PIT; VWS; IRF6_HUMAN; O14896; More at Entrez
GLI2 GLI family zinc finger 2 [Source:HGNC Symbol;Acc:4318] Functions: 1 5 7 8 18 20 22
36 38 41 44 49 51 60 67
76 82 86 91 100 104
111 112 114 119 129 132 134 137 139 140
141 142 156 161 166 175
176 177 179 183 185 196 203 210
213 223
Synonyms: ENSG00000074047; ENSP00000312694; ENSP00000344473; ENSP00000354586; ENSP00000390436; ENSP00000395688; ENSP00000397488; ENSP00000398992; ENSP00000400593; ENSP00000402383; ENSP00000403715; ENSP00000415773; ENSP00000441454; 2736; GLI2; NP_005261; NM_005270; NM_030379; NM_030380; NM_030381; HPE9; THP1; THP2; GLI2_HUMAN; P10070; More at Entrez
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) [Source:HGNC Symbol;Acc:9706] Functions: 1 24
52
Synonyms: ENSG00000110400; ENSP00000264025; ENSP00000344974; ENSP00000345289; 5818; PVRL1; NP_002846; NP_976030; NP_976031; NM_002855; NM_032767; NM_203285; NM_203286; CD111; CLPED1; ED4; HIgR; HVEC; nectin-1; OFC7; PRR1; PVRR; PVRR1; SK-12; PVRL1_HUMAN; Q15223; More at Entrez
PAX9 paired box 9 [Source:HGNC Symbol;Acc:8623] Functions: 1
Synonyms: ENSG00000198807; ENSP00000355245; ENSP00000384817; ENSP00000438524; ENSP00000450434; 5083; PAX9; NP_006185; NM_006194; STHAG3; P55771; PAX9_HUMAN;
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More at Entrez
TGFB2 transforming growth factor, beta 2 [Source:HGNC Symbol;Acc:11768] Functions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 18 19 21 22 23 24 25 26 30 31 34 35
40 41 42 45 46 47 49 50 51 52 55 56 59 61 62 63 69
71 72 73 74 79 80 85 89 90 98 99 101 103
106 107 109 113 118 120 121 128 130 131 137
154 155 158 159 164 165 167 170
178 180 183 184 192 195 197 202 205
211 217 220 221 227
Synonyms: ENSG00000092969; ENSP00000355896; ENSP00000355897; 7042; TGFB2; NP_001129071; NP_003229; NM_001135599; NM_003238; TGF-beta2; P61812; TGFB2_HUMAN; More at Entrez
JAG2 jagged 2 [Source:HGNC Symbol;Acc:6189] Functions: 1 18 22
44 51 60
86 95
111 113 116 139
175
176 178 180 210
221
Synonyms: ENSG00000184916; ENSP00000328169; ENSP00000328566; 3714; JAG2; NP_002217; NP_660142; NM_002226; NM_145159; HJ2; SER2; JAG2_HUMAN; Q9Y219; More at Entrez
MSX1 msh homeobox 1 [Source:HGNC Symbol;Acc:7391] Functions: 1 7 15 20 21 23 34
40 46
92
123 133
145 146 166 173
209
214 224
Synonyms: ENSG00000163132; ENSP00000372170; ENSP00000446928; 4487; MSX1; NP_002439; NM_002448; HOX7; HYD1; OFC5; STHAG1; MSX1_HUMAN; P28360; More at Entrez
TP63 tumor protein p63 [Source:HGNC Symbol;Acc:15979] Functions: 1 10 11 12
66 68
77 92 94 97 102 104
122 135 138
143 144 150 152
179 182 187 190 199 204 207 208 209
214 216 224 225
Synonyms: ENSG00000073282; ENSP00000264731; ENSP00000317510; ENSP00000346614; ENSP00000371495; ENSP00000376253; ENSP00000376254; ENSP00000376256; ENSP00000387839; ENSP00000389485; ENSP00000392488; ENSP00000394337; ENSP00000401661; ENSP00000407144; 8626; TP63; NP_001108450; NP_001108451; NP_001108452; NP_001108453; NP_001108454; NP_003713; NM_001114978; NM_001114979; NM_001114980; NM_001114981; NM_001114982; NM_003722; B(p51A); B(p51B); EEC3; KET; LMS; OFC8; p53CP; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L; P63_HUMAN; Q9H3D4; More at Entrez
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RARA retinoic acid receptor, alpha [Source:HGNC Symbol;Acc:9864] Functions: 1 18 22
49 51 59 60
72 76 82 86 94 98 100 103
111 114 119 122 129 134 139
150 154 155 161 162 169 175
177 181 184 185 186 189 193 194 200 202 206
220 222
Synonyms: ENSG00000131759; ENSP00000254066; ENSP00000316769; ENSP00000377643; ENSP00000377648; ENSP00000377649; ENSP00000388570; ENSP00000389993; 5914; RARA; NP_000955; NP_001019980; NP_001138773; NP_001138774; NM_000964; NM_001024809; NM_001033603; NM_001145301; NM_001145302; NR1B1; P10276; RARA_HUMAN; More at Entrez
TFAP2A (AP-2) transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) [Source:HGNC Symbol;Acc:11742] Functions: 1 7 8 10 11 12 13 17 20 27 30
36 38 41 53 57 58 61 65 67
81 87 88 94 95 96 103 104 105
112 113 115 116 127
168
179 186 189 193 194 196 203
213 226
Synonyms: ENSG00000137203; ENSP00000316516; ENSP00000368924; ENSP00000368928; ENSP00000368933; ENSP00000417495; ENSP00000417735; ENSP00000418391; ENSP00000418541; ENSP00000419696; ENSP00000419823; ENSP00000419961; ENSP00000420568; 7020; TFAP2A; NP_001027451; NP_001035890; NP_003211; NM_001032280; NM_001042425; NM_003220; AP-2; AP-2alpha; AP2TF; BOFS; TFAP2; AP2A_HUMAN; P05549; More at Entrez
TGFB3 transforming growth factor, beta 3 [Source:HGNC Symbol;Acc:11769] Functions: 1 2 3 4 5 6 7 9 10 11 12 13 14 15 16 17 19 24 25 26 28 31 32 33 35
36 37 38 39 41 42 43 45 47 48 49 50 52 54 55 56 58 59 61 62 63 64 65 69
71 72 73 74 75 78 79 80 85 88 89 90 91 93 96 98 99 101 103
106 107 108 109 110 115 117 118 120 121 123 124 125 126 127 128 132 133 136
141 145 146 147 148 149 151 153 154 156 157 158 159 160 164 165 167 170 173 174
178 180 184 191 192 197 201 202 205
211 215 217 218 219 220 223 227
Synonyms: ENSG00000119699; ENSP00000238682; ENSP00000451110; 7043; TGFB3; NP_003230; NM_003239; ARVD; TGF-beta3; P10600; TGFB3_HUMAN; More at Entrez
C10orf2 chromosome 10 open reading frame 2 [Source:HGNC Symbol;Acc:1160] Functions:
122
156
Synonyms: ENSG00000107815; ENSP00000309595; ENSP00000359248; 56652; C10orf2; NP_001157284; NP_001157285; NP_001157286; NP_068602; NM_001163812; NM_001163813; NM_001163814; NM_021830; FLJ21832; IOSCA; MTDPS7; PEO1; PEOA3; SCA8; TWINKLE; TWINL; PEO1_HUMAN; Q96RR1; More at Entrez
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TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [Source:HGNC Symbol;Acc:11773] Functions: 2 3 6 8 14 17 18 20 22 27 29 32
36 38 47 49 51 53 57 60 67 70
76 81 82 83 84 86 87 100 105
108 111 112 114 119 129 134 137 139 140
142 148 161 163 168 169 171 172 175
177 185 188 200 206
222
Synonyms: ENSG00000163513; ENSP00000295754; ENSP00000351905; ENSP00000373275; ENSP00000392572; 7048; TGFBR2; NP_001020018; NP_003233; NM_001024847; NM_003242; AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFR-2; P37173; TGFR2_HUMAN; More at Entrez
RB1 retinoblastoma 1 [Source:HGNC Symbol;Acc:9884] Functions: 21 23 34 35
40 46 66 68
77 97 102
121 135
150 155 162
186 187 189 193 194 198 204 208
212 226
Synonyms: ENSG00000139687; ENSP00000267163; ENSP00000434702; ENSP00000437642; 5925; RB1; NP_000312; NM_000321; OSRC; p105-Rb; pp110; pRb; RB; P06400; RB_HUMAN; More at Entrez
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) [Source:HGNC Symbol;Acc:15581] Functions:
Synonyms: ENSG00000008197; ENSP00000008391; 83741; TFAP2D; NP_758438; NM_172238; TFAP2BL1; AP2D_HUMAN; Q7Z6R9; More at Entrez
LHX2 LIM homeobox 2 [Source:HGNC Symbol;Acc:6594] Functions:
Synonyms: ENSG00000106689; ENSP00000362717; ENSP00000394978; ENSP00000453448; 9355; LHX2; NP_004780; NM_004789; hLhx2; LH-2; LHX2_HUMAN; P50458; More at Entrez
PVRL4 poliovirus receptor-related 4 [Source:HGNC Symbol;Acc:19688] Functions: 24
52
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Synonyms: ENSG00000143217; ENSP00000356991; ENSP00000406015; 81607; PVRL4; NP_112178; NM_030916; EDSS1; LNIR; nectin-4; PVRL4_HUMAN; Q96NY8; More at Entrez
NRIP1 nuclear receptor interacting protein 1 [Source:HGNC Symbol;Acc:8001] Functions:
104
162
186
Synonyms: ENSG00000180530; ENSP00000327213; ENSP00000383060; ENSP00000383063; ENSP00000412114; 8204; NRIP1; NP_003480; NM_003489; RIP140; NRIP1_HUMAN; P48552; More at Entrez
KDM5B lysine (K)-specific demethylase 5B [Source:HGNC Symbol;Acc:18039] Functions:
Synonyms: ENSG00000117139; ENSP00000235790; ENSP00000356233; ENSP00000356234; ENSP00000441211; ENSP00000442182; 10765; KDM5B; NP_006609; NM_006618; CT31; JARID1B; PLU-1; PLU1; PUT1; RBBP2H1A; KDM5B_HUMAN; Q9UGL1; More at Entrez
FMOD fibromodulin [Source:HGNC Symbol;Acc:3774] Functions: 6 14
69
Synonyms: ENSG00000122176; ENSP00000347041; ENSP00000408967; ENSP00000438680; 2331; FMOD; NP_002014; NM_002023; SLRR2E; FMOD_HUMAN; Q06828; More at Entrez
VASN vasorin [Source:HGNC Symbol;Acc:18517] Functions:
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Synonyms: ENSG00000168140; ENSP00000306864; 114990; VASN; NP_612449; NM_138440; SLITL2; Q6EMK4; VASN_HUMAN; More at Entrez
TGFB1 transforming growth factor, beta 1 [Source:HGNC Symbol;Acc:11766] Functions: 2 3 4 5 6 9 13 14 15 16 18 19 21 22 23 24 25 26 28 29 31 33 34 35
37 39 40 41 42 43 45 46 47 48 49 50 51 52 54 55 56 58 59 61 62 63 64 65 66 67 68 69 70
71 72 73 74 75 77 78 79 80 83 84 85 88 89 90 93 96 97 98 99 101 102 103
106 107 109 110 111 115 117 118 119 120 121 124 125 126 127 128 129 130 131 132 134 135 136
141 147 149 151 153 154 156 157 158 160 161 163 165 167 170 171 174
177 181 184 185 187 191 192 197 198 201 202 204 205 208
212 215 218 219 220 221 227
Synonyms: ENSG00000105329; ENSP00000221930; 7040; TGFB1; NP_000651; NM_000660; DPD1; TGFB; TGFbeta; P01137; TGFB1_HUMAN; More at Entrez
MFAP2 microfibrillar-associated protein 2 [Source:HGNC Symbol;Acc:7033] Functions:
Synonyms: ENSG00000117122; ENSP00000364684; ENSP00000364685; ENSP00000417029; 4237; MFAP2; NP_001128719; NP_001128720; NP_002394; NP_059453; NM_001135247; NM_001135248; NM_002403; NM_017459; MAGP; MAGP-1; MAGP1; MFAP2_HUMAN; P55001; More at Entrez
HTRA1 HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:9476] Functions:
69
Synonyms: ENSG00000166033; ENSP00000357980; ENSP00000405132; ENSP00000412676; 5654; HTRA1; NP_002766; NM_002775; ARMD7; HtrA; IGFBP5-protease; L56; ORF480; PRSS11; HTRA1_HUMAN; Q92743; More at Entrez
DLX2 distal-less homeobox 2 [Source:HGNC Symbol;Acc:2915] Functions:
112 140
Synonyms: ENSG00000115844; ENSP00000234198; ENSP00000446904; 1746; DLX2; NP_004396; NM_004405; TES-1; TES1; DLX2_HUMAN; Q07687; More at Entrez
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DLX3 distal-less homeobox 3 [Source:HGNC Symbol;Acc:2916] Functions:
Synonyms: ENSG00000064195; ENSP00000389870; ENSP00000449976; 1747; DLX3; NP_005211; NM_005220; AI4; DLX3_HUMAN; O60479; More at Entrez
ZIC1 Zic family member 1 [Source:HGNC Symbol;Acc:12872] Functions: 8 15 20 26 28 33 35
37 39 42 43 45 53 62 63 64
74 75 78 89 90 93 95 101
112 113 116 117 140
142
Synonyms: ENSG00000152977; ENSP00000282928; ENSP00000419664; 7545; ZIC1; NP_003403; NM_003412; ZIC; ZNF201; Q15915; ZIC1_HUMAN; More at Entrez
TGFBR1 transforming growth factor, beta receptor 1 [Source:HGNC Symbol;Acc:11772] Functions: 2 3 4 5 6 8 9 14 15 16 17 18 19 20 22 23 25 26 27 28 29 32 33 35
36 37 38 39 40 42 43 44 45 46 47 48 53 54 57 62 63 64 67 70
74 75 78 81 83 84 89 90 93 101 105
108 110 117 130 131 136 137
142 148 149 157 160 163 171 172
176 178 180 191 195 196 203
213 221
Synonyms: ENSG00000106799; ENSP00000364129; ENSP00000364133; ENSP00000439428; ENSP00000441620; ENSP00000446685; ENSP00000447182; ENSP00000447297; ENSP00000447707; ENSP00000448518; ENSP00000449028; ENSP00000449934; ENSP00000450052; 7046; TGFBR1; NP_001124388; NP_004603; NM_001130916; NM_004612; AAT5; ALK-5; ALK5; LDS1A; LDS2A; MSSE; SKR4; TGFR-1; P36897; TGFR1_HUMAN; More at Entrez
TP53 tumor protein p53 [Source:HGNC Symbol;Acc:11998] Functions: 10 11 12 21 23 30 34
40 46 66 68
77 87 92 94 97 102 104
121 122 135 136 138
143 144 149 150 152 157 159 160 164 168
182 187 188 189 190 193 194 199 204 207 208 209
214 216 224 225
Synonyms: ENSG00000141510; ENSP00000269305; ENSP00000352610; ENSP00000379735; ENSP00000391127; ENSP00000391478; ENSP00000394195; ENSP00000398846; ENSP00000402130; ENSP00000410739; ENSP00000423862; ENSP00000424104; ENSP00000425104; ENSP00000426252; ENSP00000437792; 7157; TP53; NP_000537; NP_001119584; NP_001119585; NP_001119586; NP_001119587; NP_001119588; NP_001119589; NP_001119590; NM_000546; NM_001126112; NM_001126113; NM_001126114; NM_001126115; NM_001126116; NM_001126117; NM_001126118; LFS1; P53; TRP53; P04637; P53_HUMAN;
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More at Entrez
LTBP3 latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:6716] Functions:
Synonyms: ENSG00000168056; ENSP00000301873; ENSP00000301874; ENSP00000326647; ENSP00000431219; ENSP00000432121; ENSP00000432350; ENSP00000432476; ENSP00000434315; ENSP00000434406; ENSP00000435146; ENSP00000435276; ENSP00000435530; ENSP00000436032; ENSP00000436341; ENSP00000441912; 4054; LTBP3; NP_001123616; NP_001157738; NP_066548; NM_001130144; NM_001164266; NM_021070; LTBP-3; pp6425; STHAG6; LTBP3_HUMAN; Q9NS15; More at Entrez
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:5034] Functions: 9 16 19 25
179
Synonyms: ENSG00000197451; ENSP00000348093; ENSP00000351108; ENSP00000422501; ENSP00000423495; ENSP00000425031; ENSP00000427110; ENSP00000427465; 3182; HNRNPAB; NP_004490; NP_112556; NM_004499; NM_031266; ABBP1; FLJ40338; HNRPAB; Q99729; ROAA_HUMAN; More at Entrez
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Functions
Function FDR Coverage 1 query genes n/a 11 / 11 2 transforming growth factor beta receptor binding 4.28E-7 5 / 15 3 pathway-restricted SMAD protein phosphorylation 3E-6 5 / 24 4 SMAD protein import into nucleus 1.68E-5 4 / 12 5 gland development 1.68E-5 6 / 83 6 transforming growth factor beta receptor signaling pathway 1.73E-5 6 / 88 7 odontogenesis 1.73E-5 5 / 41 8 embryonic organ development 3.55E-5 6 / 103 9 epithelial to mesenchymal transition 7.78E-5 5 / 58 10 regulation of neuron apoptosis 9.73E-5 5 / 62 11 neuron apoptosis 1.4E-4 5 / 68 12 neuron death 1.61E-4 5 / 73 13 positive regulation of ossification 1.61E-4 4 / 27 14 transmembrane receptor protein serine/threonine kinase signaling pathway 1.61E-4 6 / 147 15 protein localization to nucleus 2.04E-4 6 / 155 16 mesenchymal cell development 2.12E-4 5 / 80 17 palate development 2.26E-4 4 / 32 18 hemopoietic or lymphoid organ development 2.81E-4 7 / 284 19 mesenchymal cell differentiation 2.81E-4 5 / 87 20 embryonic morphogenesis 3.19E-4 6 / 176 21 negative regulation of cell growth 3.41E-4 5 / 94 22 immune system development 3.41E-4 7 / 299 23 regulation of cell growth 3.47E-4 6 / 183 24 cell-cell junction organization 3.87E-4 5 / 99 25 mesenchyme development 3.87E-4 5 / 99 26 positive regulation of protein transport 4.1E-4 5 / 101 27 embryonic cranial skeleton morphogenesis 4.51E-4 3 / 11 28 positive regulation of protein import into nucleus 4.98E-4 4 / 44 29 response to cholesterol 5.04E-4 3 / 12 30 positive regulation of neuron apoptosis 5.04E-4 3 / 12 31 exocrine system development 5.04E-4 3 / 12 32 transforming growth factor beta binding 5.04E-4 3 / 12 33 positive regulation of transmembrane transport 5.93E-4 4 / 48 34 negative regulation of growth 5.93E-4 5 / 115 35 regulation of protein localization 6.09E-4 6 / 218 36 chordate embryonic development 6.09E-4 5 / 117 37 positive regulation of nucleocytoplasmic transport 6.26E-4 4 / 50 38 embryo development ending in birth or egg hatching 6.26E-4 5 / 119 39 positive regulation of intracellular protein transport 6.99E-4 4 / 52 40 cell growth 8.85E-4 6 / 238 41 ossification 8.85E-4 5 / 129 42 protein import into nucleus 9.09E-4 5 / 131 43 positive regulation of intracellular transport 9.18E-4 4 / 57 44 neuron fate commitment 9.21E-4 3 / 16 45 nuclear import 9.31E-4 5 / 134 46 regulation of growth 9.31E-4 6 / 245 47 cytokine receptor binding 9.74E-4 5 / 136 48 positive regulation of pathway-restricted SMAD protein phosphorylation 1.02E-3 3 / 17
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Function FDR Coverage 49 positive regulation of cell differentiation 1.29E-3 6 / 262 50 positive regulation of epithelial to mesenchymal transition 1.39E-3 3 / 19 51 hemopoiesis 1.5E-3 6 / 271 52 cell junction organization 1.62E-3 5 / 154 53 embryonic organ morphogenesis 1.7E-3 4 / 70 54 regulation of pathway-restricted SMAD protein phosphorylation 1.76E-3 3 / 21 55 gland morphogenesis 1.97E-3 3 / 22 56 positive regulation of cell morphogenesis involved in differentiation 1.97E-3 3 / 22 57 embryonic skeletal system morphogenesis 2.14E-3 3 / 23 58 positive regulation of bone mineralization 2.14E-3 3 / 23 59 response to steroid hormone stimulus 2.14E-3 4 / 76 60 T cell differentiation 2.27E-3 4 / 78 61 regulation of ossification 2.27E-3 4 / 78 62 regulation of protein transport 2.32E-3 5 / 172 63 protein import 2.35E-3 5 / 173 64 regulation of protein import into nucleus 2.39E-3 4 / 80 65 positive regulation of biomineral tissue development 2.52E-3 3 / 25 66 mitotic cell cycle G1/S transition checkpoint 2.55E-3 4 / 82 67 skeletal system development 2.82E-3 5 / 182 68 G1/S transition checkpoint 2.86E-3 4 / 85 69 extracellular matrix 2.89E-3 5 / 184 70 response to lipid 2.96E-3 3 / 27 71 negative regulation of immune effector process 3.19E-3 3 / 28 72 negative regulation of cytokine production 3.19E-3 4 / 89 73 regulation of cytokine production involved in immune response 3.19E-3 3 / 28 74 regulation of establishment of protein localization 3.22E-3 5 / 191 75 regulation of nucleocytoplasmic transport 3.76E-3 4 / 94 76 positive regulation of T cell differentiation 3.76E-3 3 / 30 77 regulation of G1/S transition of mitotic cell cycle 3.76E-3 4 / 94 78 regulation of intracellular protein transport 4.03E-3 4 / 96 79 regulation of epithelial to mesenchymal transition 4.26E-3 3 / 32 80 cytokine production involved in immune response 4.26E-3 3 / 32 81 embryonic skeletal system development 4.26E-3 3 / 32 82 positive regulation of lymphocyte differentiation 4.26E-3 3 / 32 83 peptidyl-threonine phosphorylation 4.62E-3 3 / 33 84 peptidyl-threonine modification 5.95E-3 3 / 36 85 regulation of production of molecular mediator of immune response 6.39E-3 3 / 37 86 lymphocyte differentiation 6.48E-3 4 / 111 87 regulation of reactive oxygen species metabolic process 7.24E-3 3 / 39 88 regulation of bone mineralization 7.24E-3 3 / 39 89 nucleocytoplasmic transport 7.39E-3 5 / 236 90 nuclear transport 7.77E-3 5 / 239 91 mammary gland development 8.67E-3 3 / 42 92 p53 binding 8.67E-3 3 / 42 93 regulation of intracellular transport 8.85E-3 4 / 123 94 chromatin binding 8.85E-3 4 / 123 95 inner ear development 9.02E-3 3 / 43 96 regulation of biomineral tissue development 9.56E-3 3 / 44 97 regulation of interphase of mitotic cell cycle 1.05E-2 4 / 130 98 regulation of immune effector process 1.05E-2 4 / 130
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Function FDR Coverage 99 platelet alpha granule lumen 1.1E-2 3 / 47 100 regulation of T cell differentiation 1.1E-2 3 / 47 101 positive regulation of transport 1.1E-2 5 / 263 102 mitotic cell cycle checkpoint 1.1E-2 4 / 132 103 positive regulation of multicellular organismal process 1.13E-2 5 / 266 104 negative regulation of transcription from RNA polymerase II promoter 1.14E-2 5 / 267 105 skeletal system morphogenesis 1.14E-2 3 / 48 106 vesicle lumen 1.15E-2 3 / 49 107 cytoplasmic membrane-bounded vesicle lumen 1.15E-2 3 / 49 108 cytokine binding 1.15E-2 3 / 49 109 secretory granule lumen 1.15E-2 3 / 49 110 positive regulation of transmembrane receptor protein serine/threonine kinase signaling 1.15E-2 3 / 49 pathway 111 lymphocyte activation 1.38E-2 5 / 283 112 central nervous system development 1.38E-2 5 / 283 113 sensory organ development 1.38E-2 4 / 144 114 regulation of lymphocyte differentiation 1.4E-2 3 / 53 115 bone mineralization 1.4E-2 3 / 53 116 ear development 1.46E-2 3 / 54 117 regulation of transmembrane transport 1.46E-2 4 / 148 118 positive regulation of protein secretion 1.52E-2 3 / 55 119 positive regulation of lymphocyte activation 1.55E-2 4 / 151 120 production of molecular mediator of immune response 1.58E-2 3 / 56 121 positive regulation of cellular component organization 1.61E-2 5 / 297 122 structure-specific DNA binding 1.67E-2 4 / 155 123 face morphogenesis 1.71E-2 2 / 10 124 positive regulation of collagen metabolic process 1.71E-2 2 / 10 125 positive regulation of collagen biosynthetic process 1.71E-2 2 / 10 126 positive regulation of multicellular organismal metabolic process 1.71E-2 2 / 10 127 biomineral tissue development 1.74E-2 3 / 59 128 platelet alpha granule 1.82E-2 3 / 60 129 positive regulation of leukocyte activation 1.88E-2 4 / 162 130 extracellular structure organization 2.02E-2 3 / 63 131 extracellular matrix organization 2.02E-2 3 / 63 132 positive regulation of DNA metabolic process 2.02E-2 3 / 63 133 head morphogenesis 2.02E-2 2 / 11 134 positive regulation of cell activation 2.03E-2 4 / 167 135 G1/S transition of mitotic cell cycle 2.11E-2 4 / 169 136 positive regulation of protein phosphorylation 2.14E-2 4 / 170 137 heart development 2.27E-2 4 / 173 138 response to gamma radiation 2.29E-2 2 / 12 139 leukocyte differentiation 2.39E-2 4 / 176 140 brain development 2.48E-2 4 / 178 141 regulation of DNA replication 2.5E-2 3 / 69 142 pattern specification process 2.53E-2 4 / 181 143 response to X-ray 2.53E-2 2 / 13 144 DNA damage response, signal transduction by p53 class mediator resulting in 2.53E-2 2 / 13 transcription of p21 class mediator 145 body morphogenesis 2.53E-2 2 / 13 146 face development 2.53E-2 2 / 13 147 regulation of collagen biosynthetic process 2.53E-2 2 / 13
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Function FDR Coverage 148 growth factor binding 2.59E-2 3 / 71 149 positive regulation of phosphorylation 2.68E-2 4 / 185 150 chromatin 2.68E-2 4 / 185 151 regulation of collagen metabolic process 2.84E-2 2 / 14 152 DNA damage response, signal transduction resulting in transcription 2.84E-2 2 / 14 153 regulation of multicellular organismal metabolic process 2.84E-2 2 / 14 154 negative regulation of multicellular organismal process 2.89E-2 4 / 190 155 positive regulation of cell cycle 2.91E-2 3 / 75 156 DNA replication 2.91E-2 4 / 191 157 positive regulation of phosphorus metabolic process 2.93E-2 4 / 192 158 positive regulation of cell development 2.93E-2 3 / 76 159 response to hypoxia 2.93E-2 3 / 76 160 positive regulation of phosphate metabolic process 2.93E-2 4 / 192 161 regulation of lymphocyte activation 2.94E-2 4 / 193 162 intracellular steroid hormone receptor signaling pathway 2.99E-2 3 / 77 163 peptidyl-serine phosphorylation 2.99E-2 3 / 77 164 response to oxygen levels 3.05E-2 3 / 78 165 regulation of protein secretion 3.05E-2 3 / 78 166 odontogenesis of dentin-containing tooth 3.05E-2 2 / 15 167 platelet degranulation 3.27E-2 3 / 80 168 reactive oxygen species metabolic process 3.37E-2 3 / 81 169 positive regulation of alpha-beta T cell differentiation 3.38E-2 2 / 16 170 negative regulation of immune system process 3.55E-2 3 / 83 171 peptidyl-serine modification 3.55E-2 3 / 83 172 transmembrane receptor protein serine/threonine kinase activity 3.71E-2 2 / 17 173 head development 3.71E-2 2 / 17 174 collagen biosynthetic process 3.71E-2 2 / 17 175 T cell activation 3.86E-2 4 / 212 176 cell fate commitment 3.96E-2 3 / 87 177 regulation of leukocyte activation 3.96E-2 4 / 214 178 multicellular organismal reproductive process 4.08E-2 4 / 217 179 sequence-specific DNA binding 4.08E-2 4 / 217 180 multicellular organism reproduction 4.08E-2 4 / 217 181 response to estradiol stimulus 4.08E-2 2 / 18 182 DNA damage response, signal transduction by p53 class mediator resulting in induction 4.43E-2 2 / 19 of apoptosis 183 embryonic digestive tract development 4.43E-2 2 / 19 184 immune effector process 4.75E-2 4 / 227 185 regulation of cell activation 5.05E-2 4 / 231 186 transcription coactivator activity 5.25E-2 4 / 234 187 cell cycle checkpoint 5.25E-2 4 / 235 188 positive regulation of reactive oxygen species metabolic process 5.25E-2 2 / 21 189 transcription regulatory region DNA binding 5.25E-2 4 / 235 190 cellular response to UV 5.25E-2 2 / 21 191 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 5.25E-2 3 / 99 192 protein secretion 5.25E-2 3 / 99 193 regulatory region nucleic acid binding 5.25E-2 4 / 236 194 regulatory region DNA binding 5.25E-2 4 / 236 195 collagen fibril organization 5.6E-2 2 / 22 196 kidney development 5.84E-2 3 / 103 197 regulation of cell morphogenesis involved in differentiation 5.97E-2 3 / 104
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Function FDR Coverage 198 myoblast differentiation 6.03E-2 2 / 23 199 cellular response to light stimulus 6.47E-2 2 / 24 200 regulation of alpha-beta T cell differentiation 6.47E-2 2 / 24 201 collagen metabolic process 6.47E-2 2 / 24 202 regulation of cytokine production 6.64E-2 4 / 255 203 renal system development 6.64E-2 3 / 109 204 regulation of cell cycle arrest 6.64E-2 4 / 255 205 positive regulation of secretion 6.76E-2 3 / 110 206 positive regulation of alpha-beta T cell activation 6.83E-2 2 / 25 207 signal transduction by p53 class mediator resulting in induction of apoptosis 6.83E-2 2 / 25 208 regulation of mitotic cell cycle 6.98E-2 4 / 260 209 DNA damage response, signal transduction by p53 class mediator 6.98E-2 3 / 112 210 T cell differentiation in thymus 7.21E-2 2 / 26 211 ovulation cycle process 7.21E-2 2 / 26 212 regulation of lipid kinase activity 7.21E-2 2 / 26 213 urogenital system development 7.59E-2 3 / 116 214 signal transduction by p53 class mediator 7.63E-2 3 / 117 215 bone remodeling 7.63E-2 2 / 27 216 damaged DNA binding 7.63E-2 2 / 27 217 ovulation cycle 7.63E-2 2 / 27 218 negative regulation of DNA replication 8.07E-2 2 / 28 219 multicellular organismal macromolecule metabolic process 8.07E-2 2 / 28 220 cytokine production 8.07E-2 4 / 274 221 regulation of cellular component movement 8.11E-2 4 / 275 222 alpha-beta T cell differentiation 9.14E-2 2 / 30 223 positive regulation of DNA replication 9.14E-2 2 / 30 224 signal transduction in response to DNA damage 9.59E-2 3 / 128 225 DNA damage response, signal transduction resulting in induction of apoptosis 9.63E-2 2 / 31 226 core promoter binding 9.63E-2 2 / 31 227 secretory granule 9.89E-2 3 / 130
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Interactions
Gene 1 Gene 2 Weight Network group Networks KDM5B NRIP1 0.030322300270199776 Co-expression Hummel-Siebert-2006 Rieger-Chu-2004 LHX2 TP63 0.026443032547831535 Co-expression Hummel-Siebert-2006 ZIC1 TGFB2 0.023394323885440826 Co-expression Burington-Shaughnessy-2008 TFAP2A IRF6 0.019996166229248047 Co-expression Burington-Shaughnessy-2008 Hummel-Siebert-2006 TFAP2A PAX9 0.017413031309843063 Co-expression Burczynski-Dorner-2006 MFAP2 PVRL1 0.015915488824248314 Co-expression Rieger-Chu-2004 FMOD IRF6 0.010391410440206528 Co-expression Wu-Garvey-2007 MFAP2 IRF6 0.009329679422080517 Co-expression Burington-Shaughnessy-2008 Wu-Garvey-2007 PAX9 PVRL1 0.009283812716603279 Co-expression Wu-Garvey-2007 TGFB2 PVRL1 0.006707215216010809 Co-expression Wang-Maris-2006 MSX1 IRF6 0.006446447689086199 Co-expression Burington-Shaughnessy-2008 HTRA1 MSX1 0.005985565483570099 Co-expression Hummel-Siebert-2006 TGFB3 JAG2 0.005706556141376495 Co-expression Rieger-Chu-2004 HTRA1 IRF6 0.005508479196578264 Co-expression Burington-Shaughnessy-2008 TGFB3 PVRL1 0.004631760995835066 Co-expression Burington-Shaughnessy-2008 HTRA1 MFAP2 0.004230931401252747 Co-expression Hummel-Siebert-2006 HTRA1 FMOD 0.0041977232322096825 Co-expression Hummel-Siebert-2006 MFAP2 PAX9 0.0028646739665418863 Co-expression Burington-Shaughnessy-2008 TP63 IRF6 0.002354721538722515 Co-expression Burington-Shaughnessy-2008 JAG2 PAX9 0.0014399683568626642 Co-expression Rieger-Chu-2004 MSX1 PAX9 1.5251016169786453 Physical interactions IREF-CORUM IREF-HPRD IREF-SMALL-SCALE-STUDIES PVRL4 PVRL1 0.8292534947395325 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES KDM5B PAX9 0.8068496957421303 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR1 C10orf2 0.7845499292016029 Physical interactions IREF-CORUM IREF-SMALL-SCALE-STUDIES TGFB1 TGFBR2 0.6947662271559238 Physical interactions IREF-CORUM IREF-HPRD IREF-SMALL-SCALE-STUDIES C10orf2 TGFB3 0.6685316264629364 Physical interactions IREF-CORUM IREF-SMALL-SCALE-STUDIES ZIC1 GLI2 0.5827546715736389 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES FMOD TGFB3 0.5263912081718445 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES HNRNPAB TP63 0.5018821656703949 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES RB1 TFAP2A 0.5018480811268091 Physical interactions IREF-CORUM IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR2 TGFB3 0.4761476255953312 Physical interactions IREF-CORUM IREF-HPRD IREF-SMALL-SCALE-STUDIES VASN TGFB3 0.4543789029121399 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES FMOD TGFB2 0.4305608570575714 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR2 C10orf2 0.39370904862880707 Physical interactions IREF-CORUM IREF-SMALL-SCALE-STUDIES VASN TGFB2 0.3721288740634918 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES LHX2 MSX1 0.3485915809869766 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES
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Gene 1 Gene 2 Weight Network group Networks LTBP3 TGFB3 0.3418326824903488 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES LTBP3 TGFB2 0.27949759364128113 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFB1 FMOD 0.21101896464824677 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFB1 VASN 0.18330765515565872 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFB3 TGFB2 0.14342152327299118 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES LTBP3 TGFB1 0.1367778778076172 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES DLX2 MSX1 0.10467615723609924 Physical interactions IREF-SMALL-SCALE-STUDIES TGFBR2 TGFB2 0.0676720142364502 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFB1 TGFB2 0.05764662101864815 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR1 TGFB3 0.047312475740909576 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR1 TGFB2 0.0385346170514822 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES KDM5B RB1 0.038404734106734395 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES NRIP1 RARA 0.028166486881673336 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR1 TGFBR2 0.023401410318911076 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TGFBR1 TGFB1 0.018561875447630882 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TP53 TP63 0.012656926410272717 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TP53 MSX1 0.012148750014603138 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TP53 TFAP2A 0.010969385504722595 Physical interactions IREF-HPRD IREF-SMALL-SCALE-STUDIES TFAP2D TFAP2A 1.0 Predicted I2D-BIND-Mouse2Human NRIP1 RARA 0.7071067690849304 Predicted I2D-BIND-Mouse2Human HTRA1 TGFB2 0.6050424575805664 Predicted I2D-BIND-Mouse2Human MFAP2 JAG2 0.5773502588272095 Predicted I2D-BIND-Mouse2Human MSX1 PAX9 0.45636361837387085 Predicted I2D-BIND-Mouse2Human LHX2 MSX1 0.45636361837387085 Predicted I2D-BIND-Mouse2Human DLX2 MSX1 0.45636361837387085 Predicted I2D-BIND-Mouse2Human DLX3 MSX1 0.45636361837387085 Predicted I2D-BIND-Mouse2Human TP53 TP63 0.34491419792175293 Predicted I2D-BIND-Mouse2Human HTRA1 TGFB1 0.23877450823783875 Predicted I2D-BIND-Mouse2Human TGFBR1 TGFB1 0.14570926129817963 Predicted I2D-BIND-Mouse2Human TP53 TP63 0.3304758071899414 Shared protein domains INTERPRO TFAP2D TFAP2A 0.25000014901161194 Shared protein domains INTERPRO TGFB3 TGFB2 0.10863835364580154 Shared protein domains INTERPRO TGFB1 TGFB2 0.05503597855567932 Shared protein domains INTERPRO TGFB1 TGFB3 0.05503597855567932 Shared protein domains INTERPRO DLX3 DLX2 0.027821563184261322 Shared protein domains INTERPRO VASN FMOD 0.01489065308123827 Shared protein domains INTERPRO PVRL4 PVRL1 0.011909238062798977 Shared protein domains INTERPRO DLX2 MSX1 0.009253165684640408 Shared protein domains INTERPRO DLX3 MSX1 0.009251721203327179 Shared protein domains INTERPRO LTBP3 JAG2 0.008594278246164322 Shared protein domains INTERPRO ZIC1 GLI2 0.0033844253048300743 Shared protein domains INTERPRO
Search results generated by the GeneMANIA algorithm (genemania.org)
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