Exposure of Patient-Derived Mesenchymal Stromal Cells To
Author Manuscript Published OnlineFirst on July 8, 2020; DOI: 10.1158/1541-7786.MCR-20-0091 Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. 1 Research Article 2 Exposure of patient-derived mesenchymal stromal cells to TGFB1 supports fibrosis 3 induction in a pediatric acute megakaryoblastic leukemia model 4 Theresa Hack1, Stefanie Bertram2, Helen Blair3, Verena Börger4, Guntram Büsche5, Lora 5 Denson1, Enrico Fruth1, Bernd Giebel4, Olaf Heidenreich3,6, Ludger Klein-Hitpass7, 6 Laxmikanth Kollipara8, Stephanie Sendker1, Albert Sickmann8,9,10, Christiane Walter1, Nils 7 von Neuhoff1, Helmut Hanenberg1,11, Dirk Reinhardt1, Markus Schneider1,* and Mareike 8 Rasche1,* 9 1 Department of Pediatric Hematology and Oncology, University Children’s Hospital Essen, 10 Essen, Germany 11 2 Department of Pathology, University Hospital Essen, Essen, Germany 12 3 Newcastle University, Wolfson Childhood Cancer Research Centre, Translation and Clinical 13 Research Institute, Newcastle upon Tyne, United Kingdom 14 4 Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany 15 5 Department of Pathology, Hannover Medical School, Hannover, Germany 16 6 Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands 17 7 Department of Cell Biology, University Hospital Essen, Essen, Germany 18 8 Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V., Dortmund, Germany 19 9 Department of Chemistry, College of Physical Sciences, University of Aberdeen, Aberdeen, 20 Scotland, United Kingdom 21 10 Medizinische Fakultät, Medizinische Proteom-Center (MPC), Ruhr-Universität Bochum, 22 Bochum, Germany 23 11 Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich Heine University, 24 Düsseldorf, Germany 25 * These authors contributed equally to this work.
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