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Life Science Into Business

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Life Science Into Business Technology transfer for academic research A company of the LifeScience Foundation Life Science Into Business Turning Pure Science into Applied Technology Ascenion is an IP asset management company focused on the life sciences. We work closely with Range of Services public research institutions to ensure that promising scientific findings are identified, secured and brought to market to the benefit of society. On average, we evaluate 100 invention disclosures We support our partner institutes in all per year, handle 70 patent applications and negotiate some 80 revenue-generating cooperation aspects of technology transfer: and licensing agreements with industry. Moreover, we guide and support spin-offs on the road to − identify and assess commercially independence. Currently, we hold equity in 21 of these companies. All this helps create innovative attractive research results and products and jobs in growths sectors. inventions − steer and support patenting New Products processes − develop commercialization Several products based on inventions from our partners have already reached the market, among strategies others the cancer treatments Ixempra® originating from the Helmholtz Centre for Infection − steer projects towards marketplace Research and Blincyto® from the Max Delbrück Center for Molecular Medicine. Further products − initiate and negotiate licensing are in clinical development, including therapeutics against cancer and tuberculosis, diagnostics for and cooperation agreements with cardio vascular diseases and medical-technical products such as new imaging technologies. industry − coach start-ups Proceeds for Research − manage company equity − monitor contract compliance As a wholly-owned subsidiary of the LifeScience Foundation for the Promotion of Science and Re- − manage patent portfolios search, we act on behalf of inventors, their institutes, and the general public. The proceeds from com- − educate scientists about patenting mercialization and other revenues generated by Ascenion are reinvested in publicly funded research. and commercialization Learn more about the LifeScience Foundation at: www.lifescience-stiftung.com − foster dialogue between researchers, businesses and public agencies − shape the development of technology transfer. Agreements Spin-offs/Shareholdings Verträge Ausgründungen/Neubeteiligungen Ascenion is exclusive technology 2014 62 3 2014 62 3 transfer partner to numerous research 2013 59 3 2013 59 3 institutes of the Helmholtz and Leibniz 2012 85 1 2012 85 1 Associations, the Hannover Medical 2011 1 2011 1 79 School and associated79 organisations for 90 3 90 3 2010 2010 translational research. Revenues for Ascenion’s partners (million EUR) Erlöse für Ascenions Partner (Millionen EUR) 2014 0.5 7.57 2014 0.5 7.57 2013 0.8 5.69 2013 0.8 5.69 2012 0.8 6.55 2012 0.8 6.55 2011 0.4 15.7 2011 0.4 15.7 2010 0.4 2.03 2010 0.4 2.03 � Proceeds forwarded by Ascenion to the LifeScience Foundation � Revenues from agreements � Ausschüttungen von Ascenion an die LifeScience-Stiftung � Einnahmen aus Verträgen Our partners‘ revenues include fees resulting from agreements mediated by Ascenion as well as proceeds from our operative and equity business forwarded to the LifeScience Foundation. Ausgewählte Produkte, die auf Resultaten unserer Partnerinstitute basieren: Selected products originating from our partner institutions: Entwicklungsstand Development state Zentrum Präklinik Phase I Phase II Phase III Zulassung Markt Institute of origin Phase I Phase II Phase III Approval Market Therapeutika Therapeutics Ixempra | Krebs HZI • Ixempra | Cancer HZI • Blinatumomab | Krebs MDC • • Blinatumomab | Cancer MDC • • Koagulationsfaktor | Blutgerinnung MDC • Coagulation factor | Blood coagulation MDC • Vakzine | Tuberkulose VPM • Vaccine | Tuberculosis VPM • DC-Vakzine | AML HMGU • I/II DC-vaccine | AML HMGU • I/II MAGE-A1 TCR | T-Zell-Therapie MDC • I/II MAGE-A1 TCR | T-cell therapy MDC • I/II Vakzine | Prostatakrebs VPM • I/II Vaccine | Prostate cancer VPM • I/II Tubulysin-Konjugat | Tumor Therapie HZI • Tubulysin-Conjugate | Tumor Therapy HZI • Zentrum Entwicklung Markt Institute of origin Development Market Diagnostika Diagnostics Detektion JC-Virus DPZ • Detection JC Virus DPZ • ELISA | Chikungunya-Fieber BNITM • ELISA | Chikungunya fever BNITM • GDF-15 Marker | Herz-Kreislauf MHH • GDF-15 marker | Cardiovascular MHH • Detektion Autoantikörper | Alzheimer MDC • Detection Autoantibodies | Alzheimer MDC • Medizintechnik Medical Technology AKITA JET Inhalationssystem HMGU • AKITA JET nebulisation technology HMGU • Sphinkter System | Inkontinenz DLR • Sphinkter System | Incontinence DLR • Optoakust. Bildgebungsverfahren HMGU • Optoacust. imaging technology HMGU • • Hauptindikation • Weitere Indikation(en) • Primary indication • Further indication(s) Over 750 Commercial Opportunities for Industry We offer access to the intellectual property from all our partner institutes. The portfolio includes patent-protected diagnostic and therapeutic projects addressing a broad range of human diseases as well as platform technologies and commercially attractive materials such as antibodies and vectors. Browse our technology offers at www.ascenion.de/en Our Partner Institutes Helmholtz Association: LIKAT DZNE – German Centre for Neurodegenerative Diseases FZB HZDR – Helmholtz-Zentrum Dresden-Rossendorf BNITM Helmholtz Zentrum München – Research Center for Environmental Health HPI ATB Charité HZI – Helmholtz Centre for Infection Research DIfE MDC – Max Delbrück Centre for Molecular Medicine MHH HZI DRFZ TWINCORE FBH LIN MDC DPZ Leibniz Association: IPK IPF ATB – Leibniz Institute for Agricultural Engineering Potsdam-Bornim IFW HZDR BNITM – Bernhard Nocht Institute for Tropical Medicine DZNE FLI HKI DIfE – German Institute of Human Nutrition DPZ – German Primate Centre DRFZ – German Rheumatism Research Center Berlin FLI – Leibniz Institute for Age Research – Fritz Lipmann Institute FZB – Research Center Borstel – Leibniz-Center for Medicine and Biosciences HMGU HKI – Leibniz Institute for Natural Product Research and Infection Biology – Hans-Knoell-Institute HPI – Heinrich Pette Institute for Experimental Virology IFW – Leibniz Institute for Solid State and Materials Research Dresden IPK – Leibniz Institute for Plant Genetics and Crop Plant Research IPF – Leibniz Institute of Polymer Research LIKAT – Leibniz Institute for Catalysis LIN – Leibniz Institute for Neurobiology University Hospitals and Universities / Associated Organisation: Charité – Universitätsmedizin Berlin MHH – Hannover Medical School TWINCORE – Centre for Experimental and Clinical Infection Research Ascenion’s Team Berlin Our team comprises technology managers, analysts, lawyers and management consultants with Braunschweig expertise in IP, regulatory affairs, valorisation and consulting. Many of our staff members have Hamburg life-science backgrounds – in some cases combined with MBAs – and several years’ industry experience and good connections in the sector. Our offices are in Munich, Berlin, Braunschweig, Hanover Hamburg, Hanover and Neuherberg. Munich Neuherberg Ascenion’s Initiatives BioVaria: The conference brings Europe’s leading scientists and technology transfer specialists together with investors and potential licensees from the international biopharma and medtech industries. It offers a unique overview of commercially attractive projects from the best academic Ascenion GmbH research in Europe. www.biovaria.org Herzogstraße 64 Mouse Genetics Cologne (MGC)-Stiftung: The Foundation makes transgenic animal models 80803 Munich produced by Prof. Klaus Rajewsky available to industry in return for licence fees. The models are GERMANY valuable tools for drug testing and development. Proceeds from licensing are made available to fund further research. www.mgc-foundation.de T + 49 89 318814-0 F + 49 89 318814-20 Spinnovator: Venture capitalists, entrepreneurs and Ascenion’s experts work closely together in the Spinnovator, efficiently developing technologies and new companies in the fields of health, [email protected] medical technology and nutrition. www.spinnovator.de www.ascenion.de October 2015.
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