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Home , Ectodysplasin A receptor, MTCH1, YWHAZ

RT² Profiler PCR Array (384-Well Format) Human 384HT

Cat. no. 330231 PAHS-3012ZE

For pathway expression analysis

Format For use with the following real-time cyclers

RT² Profiler PCR Array, Applied Biosystems® models 7900HT (384-well block), Format E ViiA™ 7 (384-well block); Bio-Rad CFX384™

RT² Profiler PCR Array, Roche® LightCycler® 480 (384-well block) Format G

Description

The Human Apoptosis RT² Profiler PCR Array profiles the expression of 370 key involved in apoptosis, or programmed cell death. The array includes the TNF ligands and their receptors; members of the bcl-2 family, BIR (baculoviral IAP repeat) domain , CARD domain (caspase recruitment domain) proteins, death domain proteins, TRAF (TNF -associated factor) domain proteins and caspases. These 370 genes are also grouped by their functional contribution to apoptosis, either anti-apoptosis or induction of apoptosis. Using real-time PCR, you can easily and reliably analyze expression of a focused panel of genes related to apoptosis with this array.

For further details, consult the RT² Profiler PCR Array Handbook.

Sample & Assay Technologies Shipping and storage

RT² Profiler PCR Arrays in formats E and G are shipped at ambient temperature, on dry ice, or blue ice packs depending on destination and accompanying products.

For long term storage, keep plates at –20°C.

Note: Ensure that you have the correct RT² Profiler PCR Array format for your real-time cycler (see table above).

Note: Open the package and store the products appropriately immediately on receipt.

Gene table: RT² Profiler PCR Array

Position UniGene GenBank Symbol Description A01 Hs.195740 NM_012138 AATF Apoptosis antagonizing factor A02 Hs.431048 NM_005157 ABL1 C-abl oncogene 1, non- A03 Hs.438918 NM_004302 ACVR1B Activin A receptor, type IB A04 Hs.77867 NM_000674 ADORA1 Adenosine A1 receptor A05 Hs.424932 NM_004208 AIFM1 Apoptosis-inducing factor, -associated, 1 A06 Hs.655377 NM_032797 AIFM2 Apoptosis-inducing factor, mitochondrion-associated, 2 A07 Hs.163543 NM_144704 AIFM3 Apoptosis-inducing factor, mitochondrion-associated, 3 A08 Hs.525622 NM_005163 AKT1 V-akt murine thymoma viral oncogene homolog 1 A09 Hs.654431 NM_000697 ALOX12 Arachidonate 12-lipoxygenase A10 Hs.111256 NM_001141 ALOX15B Arachidonate 15-lipoxygenase, type B A11 Hs.494173 NM_000700 ANXA1 Annexin A1 A12 Hs.422986 NM_001153 ANXA4 Annexin A4 A13 Hs.728891 NM_001160 APAF1 Apoptotic peptidase activating factor 1 A14 Hs.435771 NM_006595 API5 Apoptosis inhibitor 5 A15 Hs.654439 NM_000041 APOE Apolipoprotein E A16 Hs.9754 NM_012068 ATF5 Activating 5 A17 Hs.555966 NM_020371 AVEN Apoptosis, caspase activation inhibitor A18 Hs.72885 NM_001700 AZU1 Azurocidin 1 A19 Hs.370254 NM_004322 BAD BCL2-associated agonist of cell death A20 Hs.377484 NM_004323 BAG1 BCL2-associated athanogene A21 Hs.523309 NM_004281 BAG3 BCL2-associated athanogene 3 A22 Hs.194726 NM_004874 BAG4 BCL2-associated athanogene 4 A23 Hs.485139 NM_001188 BAK1 BCL2-antagonist/killer 1 A24 Hs.624291 NM_004324 BAX BCL2-associated X B01 Hs.467020 NM_014417 BBC3 BCL2 binding component 3 B02 Hs.193516 NM_003921 BCL10 B-cell CLL/ 10 B03 Hs.150749 NM_000633 BCL2 B-cell CLL/lymphoma 2 B04 Hs.227817 NM_004049 BCL2A1 BCL2-related protein A1 B05 Hs.516966 NM_138578 BCL2L1 BCL2-like 1 B06 Hs.283672 NM_020396 BCL2L10 BCL2-like 10 (apoptosis facilitator) B07 Hs.469658 NM_006538 BCL2L11 BCL2-like 11 (apoptosis facilitator) B08 Hs.631672 NM_015367 BCL2L13 BCL2-like 13 (apoptosis facilitator) B09 Hs.410026 NM_004050 BCL2L2 BCL2-like 2 B10 Hs.31210 NM_005178 BCL3 B-cell CLL/lymphoma 3 B11 Hs.478588 NM_001706 BCL6 B-cell CLL/lymphoma 6 B12 Hs.486542 NM_014739 BCLAF1 BCL2-associated transcription factor 1 B13 Hs.502182 NM_001709 BDNF Brain-derived neurotrophic factor B14 Hs.12272 NM_003766 BECN1 Beclin 1, related B15 Hs.435556 NM_016561 BFAR Bifunctional apoptosis regulator B16 Hs.591054 NM_001196 BID BH3 interacting domain death agonist B17 Hs.475055 NM_001197 BIK BCL2-interacting killer (apoptosis-inducing) B18 Hs.696238 NM_001166 BIRC2 Baculoviral IAP repeat containing 2 B19 Hs.127799 NM_001165 BIRC3 Baculoviral IAP repeat containing 3 B20 Hs.728893 NM_001168 BIRC5 Baculoviral IAP repeat containing 5 B21 Hs.150107 NM_016252 BIRC6 Baculoviral IAP repeat containing 6 B22 Hs.256126 NM_022161 BIRC7 Baculoviral IAP repeat containing 7 B23 Hs.348263 NM_033341 BIRC8 Baculoviral IAP repeat containing 8 B24 Hs.145726 NM_001205 BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 C01 Hs.646490 NM_004330 BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 C02 Hs.144873 NM_004052 BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 Position UniGene GenBank Symbol Description C03 Hs.131226 NM_004331 BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like C04 Hs.293753 NM_032515 BOK BCL2-related ovarian killer C05 Hs.550061 NM_004333 BRAF V-raf murine sarcoma viral oncogene homolog B1 C06 Hs.194143 NM_007294 BRCA1 Breast 1, early onset C07 Hs.258314 NM_004899 BRE Brain and reproductive organ-expressed (TNFRSF1A modulator) C08 Hs.159494 NM_000061 BTK Bruton agammaglobulinemia tyrosine kinase C09 Hs.57973 NM_014550 CARD10 Caspase recruitment domain family, member 10 C10 Hs.648101 NM_032415 CARD11 Caspase recruitment domain family, member 11 C11 Hs.675480 NM_024110 CARD14 Caspase recruitment domain family, member 14 C12 Hs.44102 NM_001007232 CARD17 Caspase recruitment domain family, member 17 C13 Hs.56279 NM_021571 CARD18 Caspase recruitment domain family, member 18 C14 Hs.200242 NM_032587 CARD6 Caspase recruitment domain family, member 6 C15 Hs.694071 NM_052813 CARD9 Caspase recruitment domain family, member 9 C16 Hs.2490 NM_033292 CASP1 Caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) C17 Hs.5353 NM_001230 CASP10 Caspase 10, apoptosis-related cysteine peptidase C18 Hs.466057 NM_012114 CASP14 Caspase 14, apoptosis-related cysteine peptidase C19 Hs.368982 NM_032982 CASP2 Caspase 2, apoptosis-related cysteine peptidase C20 Hs.141125 NM_004346 CASP3 Caspase 3, apoptosis-related cysteine peptidase C21 Hs.138378 NM_001225 CASP4 Caspase 4, apoptosis-related cysteine peptidase C22 Hs.213327 NM_004347 CASP5 Caspase 5, apoptosis-related cysteine peptidase C23 Hs.654616 NM_032992 CASP6 Caspase 6, apoptosis-related cysteine peptidase C24 Hs.9216 NM_001227 CASP7 Caspase 7, apoptosis-related cysteine peptidase D01 Hs.599762 NM_001228 CASP8 Caspase 8, apoptosis-related cysteine peptidase D02 Hs.558218 NM_012115 CASP8AP2 Caspase 8 associated protein 2 D03 Hs.329502 NM_001229 CASP9 Caspase 9, apoptosis-related cysteine peptidase D04 Hs.714363 NM_003655 CBX4 Chromobox homolog 4 D05 Hs.303649 NM_002982 CCL2 Chemokine (C-C motif) 2 D06 Hs.523500 NM_001767 CD2 CD2 molecule D07 Hs.355307 NM_001242 CD27 CD27 molecule D08 Hs.591629 NM_006139 CD28 CD28 molecule D09 Hs.479214 NM_001775 CD38 CD38 molecule D10 Hs.472860 NM_001250 CD40 CD40 molecule, TNF receptor superfamily member 5 D11 Hs.592244 NM_000074 CD40LG CD40 ligand D12 Hs.58685 NM_014207 CD5 CD5 molecule D13 Hs.501497 NM_001252 CD70 CD70 molecule D14 Hs.370771 NM_000389 CDKN1A Cyclin-dependent kinase inhibitor 1A (p21, Cip1) D15 Hs.517106 NM_005194 CEBPB CCAAT/enhancer binding protein (C/EBP), beta D16 Hs.429666 NM_001806 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma D17 Hs.461361 NM_006324 CFDP1 Craniofacial development protein 1 D18 Hs.170622 NM_005507 CFL1 Cofilin 1 (non-muscle) D19 Hs.390736 NM_003879 CFLAR CASP8 and FADD-like apoptosis regulator D20 Hs.291363 NM_007194 CHEK2 CHK2 checkpoint homolog (S. pombe) D21 Hs.249129 NM_001279 CIDEA Cell death-inducing DFFA-like effector a D22 Hs.642693 NM_014430 CIDEB Cell death-inducing DFFA-like effector b D23 Hs.567562 NM_022094 CIDEC Cell death-inducing DFFA-like effector c D24 Hs.570065 NM_000091 COL4A3 Collagen, type IV, alpha 3 (Goodpasture ) E01 Hs.38533 NM_003805 CRADD CASP2 and RIPK1 domain containing adaptor with death domain E02 Hs.184085 NM_000394 CRYAA Crystallin, alpha A E03 Hs.408767 NM_001885 CRYAB Crystallin, alpha B E04 Hs.146806 NM_003592 CUL1 Cullin 1 E05 Hs.82919 NM_003591 CUL2 Cullin 2 E06 Hs.372286 NM_003590 CUL3 Cullin 3 E07 Hs.339735 NM_003589 CUL4A Cullin 4A E08 Hs.440320 NM_003478 CUL5 Cullin 5 E09 Hs.437060 NM_018947 CYCS , somatic E10 Hs.82890 NM_001344 DAD1 Defender against cell death 1 E11 Hs.75189 NM_004394 DAP Death-associated protein E12 Hs.516746 NM_004632 DAP3 Death associated protein 3 E13 Hs.380277 NM_004938 DAPK1 Death-associated protein kinase 1 E14 Hs.237886 NM_014326 DAPK2 Death-associated protein kinase 2 E15 Hs.631844 NM_001348 DAPK3 Death-associated protein kinase 3 E16 Hs.336916 NM_001350 DAXX Death-domain associated protein E17 Hs.414480 NM_001352 DBP D site of albumin promoter (albumin D-box) binding protein E18 Hs.579550 NM_005215 DCC Deleted in colorectal carcinoma E19 Hs.247362 NM_013974 DDAH2 Dimethylarginine dimethylaminohydrolase 2 E20 Hs.728989 NM_004083 DDIT3 DNA-damage-inducible transcript 3 E21 Hs.591405 NM_007204 DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 E22 Hs.517342 NM_001039711 DEDD Death effector domain containing E23 Hs.515432 NM_133328 DEDD2 Death effector domain containing 2 E24 Hs.498727 NM_014762 DHCR24 24-dehydrocholesterol reductase F01 Hs.169611 NM_019887 DIABLO Diablo, IAP-binding mitochondrial protein Position UniGene GenBank Symbol Description F02 Hs.13495 NM_006268 DPF2 D4, zinc and double PHD fingers family 2 F03 Hs.173135 NM_003583 DYRK2 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 F04 Hs.105407 NM_001399 EDA F05 Hs.171971 NM_022336 EDAR Ectodysplasin A receptor F06 Hs.433839 NM_001958 EEF1A2 Eukaryotic translation elongation factor 1 alpha 2 F07 Hs.716416 NM_004879 EI24 Etoposide induced 2.4 mRNA F08 Hs.591589 NM_004836 EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 F09 Hs.658200 NM_178040 ERC1 ELKS/RAB6-interacting/CAST family member 1 Excision repair cross-complementing rodent repair deficiency, complementation F10 Hs.487294 NM_000400 ERCC2 group 2 Excision repair cross-complementing rodent repair deficiency, complementation F11 Hs.469872 NM_000122 ERCC3 group 3 (xeroderma pigmentosum group B complementing) F12 Hs.133982 NM_001433 ERN1 Endoplasmic reticulum to nucleus signaling 1 F13 Hs.592041 NM_033266 ERN2 Endoplasmic reticulum to nucleus signaling 2 F14 Hs.655207 NM_000506 F2 Coagulation factor II (thrombin) F15 Hs.482562 NM_001992 F2R Coagulation factor II (thrombin) receptor F16 Hs.86131 NM_003824 FADD Fas (TNFRSF6)-associated via death domain F17 Hs.173438 NM_018147 FAIM Fas apoptotic inhibitory molecule F18 Hs.567424 NM_012306 FAIM2 Fas apoptotic inhibitory molecule 2 F19 Hs.244139 NM_000043 FAS Fas (TNF receptor superfamily, member 6) F20 Hs.2007 NM_000639 FASLG Fas ligand (TNF superfamily, member 6) F21 Hs.647094 NM_006712 FASTK Fas-activated serine/threonine kinase F22 Hs.362733 NM_015322 FEM1B Fem-1 homolog b (C. elegans) F23 Hs.289292 NM_023067 FOXL2 Forkhead box L2 F24 Hs.370666 NM_002015 FOXO1 Forkhead box O1 G01 Hs.220950 NM_001455 FOXO3 Forkhead box O3 G02 Hs.248114 NM_000514 GDNF Glial cell derived neurotrophic factor G03 Hs.526967 NM_207410 GFRAL GDNF family receptor alpha like G04 Hs.268849 NM_006708 GLO1 Glyoxalase I G05 Hs.76686 NM_000581 GPX1 Glutathione peroxidase 1 G06 Hs.654847 NM_000841 GRM4 Glutamate receptor, metabotropic 4 G07 Hs.523836 NM_000852 GSTP1 Glutathione S-transferase pi 1 G08 Hs.439815 NM_006402 HBXIP Hepatitis B virus x interacting protein G09 Hs.88556 NM_004964 HDAC1 Histone deacetylase 1 G10 Hs.519632 NM_003883 HDAC3 Histone deacetylase 3 G11 Hs.329266 NM_005338 HIP1 Huntingtin interacting protein 1 G12 Hs.729705 NM_022740 HIPK2 Homeodomain interacting protein kinase 2 G13 Hs.201918 NM_005734 HIPK3 Homeodomain interacting protein kinase 3 G14 Hs.593339 NM_002128 HMGB1 High mobility group box 1 G15 Hs.87247 NM_003806 HRK Harakiri, BCL2 interacting protein (contains only BH3 domain) G16 Hs.192374 NM_003299 HSP90B1 Heat shock protein 90kDa beta (Grp94), member 1 G17 Hs.274402 NM_005346 HSPA1B Heat shock 70kDa protein 1B G18 Hs.184233 NM_004134 HSPA9 Heat shock 70kDa protein 9 (mortalin) G19 Hs.520973 NM_001540 HSPB1 Heat shock 27kDa protein 1 G20 Hs.1197 NM_002157 HSPE1 Heat shock 10kDa protein 1 (chaperonin 10) G21 Hs.90753 NM_006410 HTATIP2 HIV-1 Tat interactive protein 2, 30kDa G22 Hs.518450 NM_002111 HTT Huntingtin G23 Hs.591785 NM_003897 IER3 Immediate early response 3 G24 Hs.380250 NM_005531 IFI16 Interferon, gamma-inducible protein 16 H01 Hs.730125 NM_002038 IFI6 Interferon, alpha-inducible protein 6 H02 Hs.211575 NM_000605 IFNA2 Interferon, alpha 2 H03 Hs.93177 NM_002176 IFNB1 Interferon, beta 1, fibroblast H04 Hs.856 NM_000619 IFNG Interferon, gamma H05 Hs.412196 NM_018010 IFT57 Intraflagellar transport 57 homolog (Chlamydomonas) H06 Hs.643120 NM_000875 IGF1R -like 1 receptor H07 Hs.252543 NM_201612 IKBIP IKBKB interacting protein H08 Hs.43505 NM_003639 IKBKG Inhibitor of kappa light polypeptide enhancer in B-cells, kinase gamma H09 Hs.193717 NM_000572 IL10 Interleukin 10 H10 Hs.83077 NM_001562 IL18 Interleukin 18 (interferon-gamma-inducing factor) H11 Hs.661017 NM_013371 IL19 Interleukin 19 H12 Hs.1722 NM_000575 IL1A Interleukin 1, alpha H13 Hs.89679 NM_000586 IL2 Interleukin 2 H14 Hs.55378 NM_139017 IL31RA Interleukin 31 receptor A H15 Hs.407506 NM_002191 INHA Inhibin, alpha H16 Hs.583348 NM_002192 INHBA Inhibin, beta A H17 Hs.482605 NM_152405 JMY Junction mediating and regulatory protein, cofactor H18 Hs.72938 NM_002289 LALBA Lactalbumin, alpha- H19 Hs.470627 NM_005356 LCK Lymphocyte-specific protein tyrosine kinase H20 Hs.445351 NM_002305 LGALS1 Lectin, galactoside-binding, soluble, 1 H21 Hs.36 NM_000595 LTA Lymphotoxin alpha (TNF superfamily, member 1) H22 Hs.376208 NM_002341 LTB Lymphotoxin beta (TNF superfamily, member 3) Position UniGene GenBank Symbol Description H23 Hs.1116 NM_002342 LTBR Lymphotoxin beta receptor (TNFR superfamily, member 3) H24 Hs.82548 NM_003682 MADD MAP-kinase activating death domain I01 Hs.80395 NM_002371 MAL Mal, T-cell differentiation protein I02 Hs.601217 NM_173844 MALT1 Mucosa associated lymphoid tissue lymphoma translocation gene 1 I03 Hs.466743 NM_002446 MAP3K10 Mitogen-activated protein kinase kinase kinase 10 I04 Hs.186486 NM_005923 MAP3K5 Mitogen-activated protein kinase kinase kinase 5 I05 Hs.431850 NM_002745 MAPK1 Mitogen-activated protein kinase 1 I06 Hs.138211 NM_002750 MAPK8 Mitogen-activated protein kinase 8 I07 Hs.558180 NM_012324 MAPK8IP2 Mitogen-activated protein kinase 8 interacting protein 2 I08 Hs.35947 NM_003925 MBD4 Methyl-CpG binding domain protein 4 I09 Hs.632486 NM_021960 MCL1 Myeloid cell leukemia sequence 1 (BCL2-related) I10 Hs.654688 NM_020831 MKL1 Megakaryoblastic leukemia (translocation) 1 I11 Hs.24719 NM_022151 MOAP1 Modulator of apoptosis 1 I12 Hs.458272 NM_000250 MPO Myeloperoxidase I13 Hs.445052 NM_000179 MSH6 MutS homolog 6 (E. coli) I14 Hs.485262 NM_014341 MTCH1 1 I15 Hs.145932 NM_004923 MTL5 Metallothionein-like 5, testis-specific (tesmin) I16 Hs.517307 NM_002462 MX1 Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) I17 Hs.179718 NM_002466 MYBL2 V-myb myeloblastosis viral oncogene homolog (avian)-like 2 I18 Hs.202453 NM_002467 MYC V-myc myelocytomatosis viral oncogene homolog (avian) I19 Hs.708160 NM_078471 MYO18A Myosin XVIIIA I20 Hs.710305 NM_004536 NAIP NLR family, apoptosis inhibitory protein I21 Hs.534453 NM_015965 NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q I22 Hs.502528 NM_004551 NDUFS3 reductase) I23 Hs.654408 NM_003998 NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 I24 Hs.73090 NM_002502 NFKB2 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) J01 Hs.415768 NM_002507 NGFR Nerve growth factor receptor J02 Hs.590927 NM_001189 NKX3-2 NK3 homeobox 2 J03 Hs.574741 NM_021209 NLRC4 NLR family, CARD domain containing 4 J04 Hs.104305 NM_033004 NLRP1 NLR family, pyrin domain containing 1 J05 Hs.631573 NM_033297 NLRP12 NLR family, pyrin domain containing 12 J06 Hs.369279 NM_017852 NLRP2 NLR family, pyrin domain containing 2 J07 Hs.159483 NM_183395 NLRP3 NLR family, pyrin domain containing 3 J08 Hs.514065 NM_002513 NME3 Non-metastatic cells 3, protein expressed in J09 Hs.715767 NM_003551 NME5 Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) J10 Hs.405153 NM_006092 NOD1 Nucleotide-binding oligomerization domain containing 1 J11 Hs.592072 NM_022162 NOD2 Nucleotide-binding oligomerization domain containing 2 J12 Hs.513667 NM_003946 NOL3 Nucleolar protein 3 (apoptosis repressor with CARD domain) J13 Hs.487360 NM_024408 NOTCH2 Notch 2 J14 Hs.657932 NM_024505 NOX5 NADPH oxidase, EF-hand calcium binding domain 5 J15 Hs.557550 NM_199185 NPM1 Nucleophosmin (nucleolar phosphoprotein B23, numatrin) J16 Hs.408515 NM_013982 NRG2 Neuregulin 2 J17 Hs.99171 NM_002527 NTF3 Neurotrophin 3 J18 Hs.493767 NM_001161 NUDT2 Nudix (nucleoside diphosphate linked moiety X)-type motif 2 J19 Hs.513463 NM_012385 NUPR1 Nuclear protein, transcriptional regulator, 1 J20 Hs.594504 NM_130837 OPA1 Optic atrophy 1 (autosomal dominant) J21 Hs.32539 NM_177990 PAK7 P21 protein (Cdc42/Rac)-activated kinase 7 J22 Hs.113253 NM_002584 PAX7 Paired box 7 J23 Hs.20930 NM_020418 PCBP4 Poly(rC) binding protein 4 J24 Hs.443831 NM_004708 PDCD5 Programmed cell death 5 K01 Hs.379186 NM_013232 PDCD6 Programmed cell death 6 K02 Hs.517216 NM_003768 PEA15 Phosphoprotein enriched in astrocytes 15 K03 Hs.592290 NM_145886 PIDD P53-induced death domain protein K04 Hs.553498 NM_006218 PIK3CA Phosphoinositide-3-kinase, catalytic, alpha polypeptide K05 Hs.371344 NM_005027 PIK3R2 Phosphoinositide-3-kinase, regulatory subunit 2 (beta) K06 Hs.496096 NM_006875 PIM2 Pim-2 oncogene K07 Hs.715495 NM_002656 PLAGL1 Pleiomorphic adenoma gene-like 1 K08 Hs.154104 NM_002657 PLAGL2 Pleiomorphic adenoma gene-like 2 K09 Hs.466383 NM_024310 PLEKHF1 Pleckstrin homology domain containing, family F (with FYVE domain) member 1 K10 Hs.143436 NM_000301 PLG Plasminogen K11 Hs.96 NM_021127 PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1 K12 Hs.526464 NM_033238 PML Promyelocytic leukemia K13 Hs.432752 NM_017542 POGK Pogo transposable element with KRAB domain K14 Hs.654484 NM_002690 POLB Polymerase (DNA directed), beta K15 Hs.654522 NM_006237 POU4F1 POU class 4 homeobox 1 K16 Hs.709297 NM_015316 PPP1R13B , regulatory (inhibitor) subunit 13B K17 Hs.483408 NM_002715 PPP2CA Protein phosphatase 2, catalytic subunit, alpha isozyme K18 Hs.467192 NM_014225 PPP2R1A Protein phosphatase 2, regulatory subunit A, alpha K19 Hs.584790 NM_002716 PPP2R1B Protein phosphatase 2, regulatory subunit A, beta K20 Hs.432121 NM_005809 PRDX2 Peroxiredoxin 2 Position UniGene GenBank Symbol Description K21 Hs.43322 NM_006251 PRKAA1 Protein kinase, AMP-activated, alpha 1 catalytic subunit K22 Hs.531704 NM_002737 PRKCA Protein kinase C, alpha K23 Hs.580351 NM_005400 PRKCE Protein kinase C, epsilon K24 Hs.496255 NM_002744 PRKCZ Protein kinase C, zeta L01 Hs.570274 NM_003690 PRKRA Protein kinase, interferon-inducible double stranded RNA dependent activator L02 Hs.368587 NM_000949 PRLR Prolactin receptor L03 Hs.517352 NM_016335 PRODH Proline dehydrogenase (oxidase) 1 L04 Hs.528665 NM_021935 PROK2 Prokineticin 2 L05 Hs.158301 NM_006261 PROP1 PROP paired-like homeobox 1 L06 Hs.262857 NM_015225 PRUNE2 Prune homolog 2 (Drosophila) L07 Hs.3260 NM_000021 PSEN1 1 L08 Hs.500466 NM_000314 PTEN Phosphatase and tensin homolog L09 Hs.37045 NM_000315 PTH Parathyroid hormone L10 Hs.499094 NM_013258 PYCARD PYD and CARD domain containing L11 Hs.1497 NM_000966 RARG Retinoic acid receptor, gamma L12 Hs.664080 NM_002890 RASA1 RAS p21 protein activator (GTPase activating protein) 1 L13 Hs.502875 NM_021975 RELA V-rel reticuloendotheliosis viral oncogene homolog A (avian) L14 Hs.523744 NM_022457 RFWD2 Ring finger and WD repeat domain 2 L15 Hs.519842 NM_003804 RIPK1 Receptor (TNFRSF)-interacting serine-threonine kinase 1 L16 Hs.103755 NM_003821 RIPK2 Receptor-interacting serine-threonine kinase 2 L17 Hs.268551 NM_006871 RIPK3 Receptor-interacting serine-threonine kinase 3 L18 Hs.134623 NM_014245 RNF7 Ring finger protein 7 L19 Hs.356572 NM_001006 RPS3A Ribosomal protein S3A L20 Hs.704007 NM_007008 RTN4 Reticulon 4 L21 Hs.170019 NM_004350 RUNX3 Runt-related transcription factor 3 L22 Hs.422181 NM_006272 S100B S100 calcium binding protein B L23 Hs.655088 NM_013260 SAP30BP SAP30 binding protein L24 Hs.502883 NM_005146 SART1 Squamous cell carcinoma antigen recognized by T cells Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and M01 Hs.655281 NM_006378 SEMA4D short cytoplasmic domain, (semaphorin) 4D M02 Hs.272168 NM_006811 SERINC3 Serine incorporator 3 M03 Hs.594481 NM_002575 SERPINB2 Serpin peptidase inhibitor, clade B (ovalbumin), member 2 M04 Hs.104879 NM_004155 SERPINB9 Serpin peptidase inhibitor, clade B (ovalbumin), member 9 M05 Hs.523718 NM_006142 SFN Stratifin M06 Hs.713546 NM_003012 SFRP1 Secreted -related protein 1 M07 Hs.136309 NM_016009 SH3GLB1 SH3-domain GRB2-like endophilin B1 M08 Hs.530477 NM_006747 SIPA1 Signal-induced proliferation-associated 1 M09 Hs.632093 NM_005871 SMNDC1 Survival motor neuron domain containing 1 M10 Hs.271771 NM_000345 SNCA Synuclein, alpha (non A4 component of amyloid precursor) M11 Hs.485572 NM_003877 SOCS2 Suppressor of cytokine signaling 2 M12 Hs.527973 NM_003955 SOCS3 Suppressor of cytokine signaling 3 M13 Hs.517262 NM_138927 SON SON DNA binding protein M14 Hs.68061 NM_021972 SPHK1 Sphingosine kinase 1 M15 Hs.632188 NM_003123 SPN Sialophorin M16 Hs.313 NM_000582 SPP1 Secreted phosphoprotein 1 M17 Hs.12409 NM_001048 SST Somatostatin M18 Hs.225995 NM_001051 SSTR3 Somatostatin receptor 3 M19 Hs.657598 NM_006463 STAMBP STAM binding protein M20 Hs.642990 NM_007315 STAT1 Signal transducer and activator of transcription 1, 91kDa M21 Hs.437058 NM_003152 STAT5A Signal transducer and activator of transcription 5A M22 Hs.595276 NM_012448 STAT5B Signal transducer and activator of transcription 5B M23 Hs.706869 NM_004760 STK17A Serine/threonine kinase 17a M24 Hs.710234 NM_004226 STK17B Serine/threonine kinase 17b N01 Hs.34576 NM_006024 TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 N02 Hs.505874 NM_013254 TBK1 TANK-binding kinase 1 N03 Hs.714737 NM_016569 TBX3 T-box 3 N04 Hs.381715 NM_181486 TBX5 T-box 5 N05 Hs.385870 NM_003212 TDGF1 Teratocarcinoma-derived growth factor 1 N06 Hs.645227 NM_000660 TGFB1 Transforming growth factor, beta 1 N07 Hs.728844 NM_022037 TIA1 TIA1 cytotoxic granule-associated RNA binding protein N08 Hs.462590 NM_004740 TIAF1 TGFB1-induced anti-apoptotic factor 1 N09 Hs.501203 NM_003252 TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 N10 Hs.644633 NM_000362 TIMP3 TIMP metallopeptidase inhibitor 3 N11 Hs.519033 NM_003264 TLR2 Toll-like receptor 2 N12 Hs.125221 NM_030755 TMX1 Thioredoxin-related transmembrane protein 1 N13 Hs.241570 NM_000594 TNF Tumor factor N14 Hs.211600 NM_006290 TNFAIP3 Tumor necrosis factor, alpha-induced protein 3 N15 Hs.656274 NM_014350 TNFAIP8 Tumor necrosis factor, alpha-induced protein 8 N16 Hs.591834 NM_003844 TNFRSF10A Tumor necrosis factor receptor superfamily, member 10a N17 Hs.521456 NM_003842 TNFRSF10B Tumor necrosis factor receptor superfamily, member 10b

N18 Hs.213467 NM_003840 TNFRSF10D Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated Position UniGene GenBank Symbol Description death domain N19 Hs.212680 NM_004195 TNFRSF18 Tumor necrosis factor receptor superfamily, member 18 N20 Hs.149168 NM_018647 TNFRSF19 Tumor necrosis factor receptor superfamily, member 19 N21 Hs.279594 NM_001065 TNFRSF1A Tumor necrosis factor receptor superfamily, member 1A N22 Hs.256278 NM_001066 TNFRSF1B Tumor necrosis factor receptor superfamily, member 1B N23 Hs.443577 NM_014452 TNFRSF21 Tumor necrosis factor receptor superfamily, member 21 N24 Hs.462529 NM_003790 TNFRSF25 Tumor necrosis factor receptor superfamily, member 25 O01 Hs.434878 NM_003823 TNFRSF6B Tumor necrosis factor receptor superfamily, member 6b, decoy O02 Hs.1314 NM_001243 TNFRSF8 Tumor necrosis factor receptor superfamily, member 8 O03 Hs.654459 NM_001561 TNFRSF9 Tumor necrosis factor receptor superfamily, member 9 O04 Hs.478275 NM_003810 TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 O05 Hs.129708 NM_003807 TNFSF14 Tumor necrosis factor (ligand) superfamily, member 14 O06 Hs.241382 NM_005118 TNFSF15 Tumor necrosis factor (ligand) superfamily, member 15 O07 Hs.248197 NM_005092 TNFSF18 Tumor necrosis factor (ligand) superfamily, member 18 O08 Hs.654445 NM_001244 TNFSF8 Tumor necrosis factor (ligand) superfamily, member 8 O09 Hs.654481 NM_000546 TP53 Tumor protein p53 O10 Hs.523968 NM_005426 TP53BP2 Tumor protein p53 binding protein, 2 O11 Hs.50649 NM_004881 TP53I3 Tumor protein p53 inducible protein 3 O12 Hs.137569 NM_003722 TP63 Tumor protein p63 O13 Hs.697294 NM_005427 TP73 Tumor protein p73 O14 Hs.591347 NM_003287 TPD52L1 Tumor protein D52-like 1 O15 Hs.374596 NM_003295 TPT1 Tumor protein, translationally-controlled 1 O16 Hs.460996 NM_003789 TRADD TNFRSF1A-associated via death domain O17 Hs.522506 NM_021138 TRAF2 TNF receptor-associated factor 2 O18 Hs.510528 NM_003300 TRAF3 TNF receptor-associated factor 3 O19 Hs.523930 NM_004619 TRAF5 TNF receptor-associated factor 5 O20 Hs.591983 NM_004620 TRAF6 TNF receptor-associated factor 6 O21 Hs.643537 NM_032271 TRAF7 TNF receptor-associated factor 7 O22 Hs.517972 NM_005879 TRAIP TRAF interacting protein O23 Hs.69499 NM_016399 TRIAP1 TP53 regulated inhibitor of apoptosis 1 O24 Hs.716410 NM_004089 TSC22D3 TSC22 domain family, member 3 P01 Hs.493791 NM_006377 UNC13B Unc-13 homolog B (C. elegans) P02 Hs.472038 NM_016037 UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) P03 Hs.529782 NM_007126 VCP Valosin containing protein P04 Hs.73793 NM_003376 VEGFA Vascular endothelial growth factor A P05 Hs.517792 NM_000551 VHL Von Hippel-Lindau tumor suppressor P06 Hs.356076 NM_001167 XIAP X-linked inhibitor of apoptosis Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, P07 Hs.492407 NM_003406 YWHAZ zeta polypeptide P08 Hs.444451 NM_016653 ZAK Sterile alpha motif and leucine zipper containing kinase AZK P09 Hs.194157 NM_016478 ZC3HC1 Zinc finger, C3HC-type containing 1 P10 Hs.631623 NM_005815 ZNF443 Zinc finger protein 443 P11 Hs.520640 NM_001101 ACTB Actin, beta P12 Hs.534255 NM_004048 B2M Beta-2-microglobulin P13 Hs.592355 NM_002046 GAPDH Glyceraldehyde-3-phosphate dehydrogenase P14 Hs.412707 NM_000194 HPRT1 Hypoxanthine phosphoribosyltransferase 1 P15 Hs.546285 NM_001002 RPLP0 Ribosomal protein, large, P0 P16 N/A SA_00105 HGDC Human Genomic DNA Contamination P17 N/A SA_00105 HGDC Human Genomic DNA Contamination P18 N/A SA_00105 HGDC Human Genomic DNA Contamination P19 N/A SA_00104 RTC Reverse Transcription Control P20 N/A SA_00104 RTC Reverse Transcription Control P21 N/A SA_00104 RTC Reverse Transcription Control P22 N/A SA_00103 PPC Positive PCR Control P23 N/A SA_00103 PPC Positive PCR Control P24 N/A SA_00103 PPC Positive PCR Control Related products

For optimal performance, RT² Profiler PCR Arrays should be used together with the RT² First Strand Kit for cDNA synthesis and RT² SYBR® Green qPCR Mastermixes for PCR.

Product Contents Cat. no.

RT² First Strand Kit (12) Enzymes and reagents for cDNA synthesis 330401

RT² SYBR Green qPCR For 4 x 384 assays in 384-well plates; suitable for 330501 Mastermix (8)* use with real-time cyclers that do not require a reference dye, including: Bio-Rad model CFX384; Roche LightCycler 480 (384-well); all other cyclers

RT² SYBR Green ROX™ qPCR For 4 x 384 assays in 384-well plates; suitable for 330521 Mastermix (8)* use with the following real-time cyclers: Applied Biosystems models 7900HT, ViiA 7 (384-well blocks)

RT² SYBR Green Fluor qPCR For 4 x 384 assays in 384-well plates; suitable for 330511 Mastermix (8)* use with the following real-time cyclers: Bio-Rad models iCycler®, iQ™5, MyiQ™, MyiQ2

* Larger sizes available; please inquire.

RT² Profiler PCR Array products are intended for molecular biology applications. These products are not intended for the diagnosis, prevention, or treatment of a .

For up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit handbook or user manual. QIAGEN kit handbooks and user manuals are available at www.qiagen. com or can be requested from QIAGEN Technical Services or your local distributor.

Trademarks: QIAGEN®(QIAGEN Group); Applied Biosystems®, ViiA™, ROX™ (Applera Corporation or its subsidiaries); Bio-Rad®, CFX384™, iQ™, MyiQ™. iCycler® (Bio-Rad Laboratories,Inc.); Roche®, LightCycler® (Roche Group); SYBR®(Molecular Probes, Inc.). 1067687 03/2011 © 2011 QIAGEN, all rights reserved.

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