C ATP-binding cassette, subfamily B A ComEA WP 025028831 Bacillus mannanilyticus B oxaloacetate decarboxylase, beta subunit WP 041718914 Alkaliphilus oremlandii PKM81186 Firmicutes bacterium HGW-Firmicutes-14 WP 092588843 Acidaminobacter hydrogenoformans Bacillus spp. MZQ96192 Acidaminobacter sp. Paenibacillus spp. 100% WP 088775865 Carboxydothermus islandicus WP 152967700 Oxobacter pfennigii GAV25686 Carboxydothermus islandicus WP 057983007 Virgibacillus soli 70% WP 146620656 Enterococcus florum WP 049886177 Thermacetogenium phaeum WP 064467709 Bacillus galactosidilyticus WP 126109031 Jeotgalibaca sp. H21T32 WP 090886300 Bacillus caseinilyticus Tree scale: 0.1 Peptoclostridium spp. Trichococcus spp. WP 101330798 Halalkalibacillus sp. B3227 WP 156782411 Geosporobacter ferrireducens WP 078755654 Globicatella sulfidifaciens SFQ43799 Desemzia incerta WP 110940224 Geosporobacter subterraneus WP 051258417 Atopococcus tabaci WP 047393312 Carnobacterium sp. ZWU0011 SHI93557 Geosporobacter subterraneus DSM 17957 WP 156883193 Lacticigenium naphtae WP 051237935 Lacticigenium naphtae 100% Natranaerovirga spp. WP 017470521 Amphibacillus jilinensis WP 097004362 amygdalinum Enterococcus spp. 75% HBG15709 Firmicutes bacterium WP 092653112 Isobaculum melis WP 013780596 Mahella australiensis Thermoanaerobacter spp. WP 126780365 Vagococcus salmoninarum WP 087058768 Marinilactibacillus psychrotolerans WP 084110983 Caldanaerobius fijiensis WP 072693424 Marinilactibacillus sp. 15R 2503533728 Mahella australiensis 50-1 BON Caldicellulosiruptor spp. WP 129721893 Clostridiales bacterium SYSU GA17129 WP 034551516 Carnobacterium funditum WP 085558888 Carnobacterium iners WP 035172562 Caldanaerobius polysaccharolyticus WP 035030695 Carnobacterium mobile WP 148866388 Thermosediminibacter litoriperuensis WP 092091739 Pisciglobus halotolerans Tree scale: 0.1 WP 092479393 Desemzia incerta WP 066355053 Fervidicola ferrireducens WP 047390226 Carnobacterium sp. ZWU0011 WP 073256848 Caldanaerovirga acetigignens WP 129724577 Clostridiales bacterium SYSU GA17129 WP 035618223 Lacticigenium naphtae WP 051258509 Atopococcus tabaci Caldicellulosiruptor spp. WP 013780593 Mahella australiensis WP 161878756 Alkalibacterium sp. MB6 WP 091732591 Proteiniborus ethanoligenes WP 068557831 Thermotalea metallivorans Carnobacterium spp. WP 069981092 Geosporobacter ferrireducens WP 083273835 Geosporobacter ferrireducens

SHI50782 Geosporobacter subterraneus DSM 17957 WP 110940295 Geosporobacter subterraneus Marinilactibacillus spp. 100% SHI95638 Geosporobacter subterraneus DSM 17957 WP 068554877 Thermotalea metallivorans 70% WP 053956992 Inediibacterium massiliense TXT49091 Spirochaetes bacterium Coprothermobacter spp. WP 122013730 Christensenella sp. Marseille-P3954 WP 129597337 Clostridiaceae bacterium MJB2 ADM94926 uncultured Candidatus Atribacteria bacterium WP 147518066 Clostridiaceae bacterium Tree scale: 0.1 WP 148809203 Crassaminicella sp. SY095 SCJ22543 uncultured Clostridium sp. WP 013781790 Mahella australiensis WP 132242701 Marinisporobacter balticus WP 138295909 Clostridium sp. BSD2780061688st1 E8 WP 121958705 Petrotoga sp. 9PWA.NaAc.5.4 PMP78973 Mesoaciditoga sp. WP 074351176 Proteiniborus sp. DW1 WP 113075498 Petrotoga sp. 9PW.55.5.1 BBJ27901 Athalassotoga saccharophila WP 091726468 Proteiniborus ethanoligenes WP 045088399 Defluviitoga tunisiensis WP 161847846 Athalassotoga saccharophila TAH64304 Anaerolineaceae bacterium WP 103077420 Petrotoga mexicana RKX34253 Thermotogae bacterium Tissierellales spp. POZ92254 Petrotoga halophila DSM 16923 RKX43025 Thermotogae bacterium WP 132028356 Keratinibaculum paraultunense WP 103079499 Petrotoga miotherma Pseudothermotoga spp. WP_053963172_unclassified Clostridiales WP 049755351 Petrotoga mobilis WP 132996078 Sporanaerobacter acetigenes Thermotoga spp. WP 103066106 Petrotoga olearia WP 042678573 Anaerosalibacter massiliensis WP 121515169 Petrotoga sp. HKA.pet.4.5 WP 077368902 Anaerosalibacter sp. Marseille-P3206 RKX45149 Thermotogae bacterium WP 032123611 Clostridium amazonitimonense 2572228733 Petrotoga sp. 8T1HF07.NaAc.6.1 HCZ06355 Thermotogae bacterium WP 055665239 Desnuesiella massiliensis WP 121958814 Petrotoga sp. 9T1HF07.CasAA.8.2 WP 138203422 Haloimpatiens lingqiaonensis WP 121567381 Petrotoga sp. Shatin.DS.tank11.9.2.9.3 Mesotoga spp. WP 102399473 Khelaifiella massiliensis WP 103065687 Petrotoga sp. HWHPT.55.6.3 WP 035292670 Clostridium sp. KNHs214 WP 123821425 Petrotoga sp. HWH.PT.55.6.1 Kosmotoga spp. CDF59104 Thermobrachium celere DSM 8682 WP 051150583 Thermobrachium celere HAI87220 Firmicutes bacterium WP 027309049 Caloramator sp. ALD01 Actinobacteria spp. Fervidobacterium spp. SHF07358 Caloramator proteoclasticus DSM 10124 WP 084106657 Caloramator proteoclasticus GAV32211 Coriobacteriaceae bacterium EMTCatB1 Thermosipho spp. WP 094366828 Romboutsia weinsteinii OFW57222 Actinobacteria bacterium RBG 16 64 13 HBK84687 Firmicutes bacterium RKX54855 Thermotoga sp. WP 026485998 Caldanaerobius polysaccharolyticus Chloroflexi bacterium spp. Marinitoga spp. WP 073345650 Caldanaerobius fijiensis WP 096233476 Thermoanaerobacterium sp. RBIITD Chloroflexi bacterium spp. WP 109603821 Oceanotoga teriensis WP 003869068 Thermoanaerobacter ethanolicus WP 135402601 Geotoga petraea WP 074665633 Thermoanaerobacter thermohydrosulfuricus WP 141789874 Oryzihumus leptocrescens WP 091402256 Geotoga petraea WP 042834190 Thermoanaerobacter sp. YS13 WP 022587481 Caldanaerobacter subterraneus WP 139106986 Mumia sp. Z527 WP 045088467 Defluviitoga tunisiensis WP 009610020 Caldanaerobacter subterraneus WP 039348727 Mumia flava WP 068554563 Thermotalea metallivorans WP 141957508 Actinoallomurus bryophytorum WP 113073651 Petrotoga sp. 9PW.55.5.1 WP 103081172 Pseudoclostridium thermosuccinogenes WP 157631242 Catelliglobosispora koreensis WP 121958130 Petrotoga sp. 9PWA.NaAc.5.4 WP 069193962 Clostridiales HCT79401 Micromonosporaceae bacterium PNR94465 Petrotoga sp. 9PWA.NaAc.5.4 WP 038289160 Hungateiclostridium straminisolvens WP 003518007 Hungateiclostridium thermocellum WP 109133197 Cellulomonas sp. WB94 WP 103067232 Petrotoga olearia WP 013779695 Mahella australiensis Cellulomonas spp. KUK82010 Petrotoga mobilis WP 068749207 Thermovenabulum gondwanense WP 103876932 Petrotoga WP 144016950 Beutenbergia cavernae WP 120766489 Thermoanaerobacterales WP 103076743 Petrotoga mexicana WP 013276302 Thermosediminibacter oceani Cellulomonas spp. WP 103079102 Petrotoga PZN04256 Firmicutes bacterium WP 066350690 Fervidicola ferrireducens WP 115850749 Thermasporomyces composti WP 012209049 Petrotoga mobilis RKX64439 candidate division TA06 bacterium WP 030918385 Streptosporangium amethystogenes WP 121567249 Petrotoga sp. Shatin.DS.tank11.9.2.9.3 PKN79773 Candidatus Cloacimonetes bacterium HGW-Cloacimonetes-1 RQV92520 bacterium Rhodococcus spp. 2572229732 Petrotoga sp. 8T1HF07.NaAc.6.1 WP 144683200 Desulfobotulus alkaliphilus NDL60863 Phytoactinopolyspora sp. XMNu-373 WP 139447101 Desulfobotulus sp. PAR22N WP 103064872 unclassified Petrotoga RKX56515 Thermotoga sp. WP 026875417 Jiangella gansuensis WP 121514761 Petrotoga sp. 9T1HF07.CasAA.8.2 WP 036223367 Mesoaciditoga lauensis WP 015746133 Nakamurella multipartita Kosmotoga spp. and Mesotoga spp. Microbacterium spp. RKX54619 Thermotoga sp. ODU65792 Leifsonia sp. SCN 70-46 HCZ06801 Thermotogae bacterium RKX45705 Thermotogae bacterium Agromyces spp. RKX57037 Thermotoga sp. Thermotoga spp.

Thermosipho spp.

Fervidobacterium spp.

Pseudothermotoga spp.

Marinitoga spp.

WP 109604002 Oceanotoga teriensis WP 091403634 Geotoga petraea WP 135403012 Geotoga petraea WP 121957003 Petrotoga sp. 9PWA.NaAc.5.4 WP 045087964 Defluviitoga tunisiensis WP 113075352 Petrotoga sp. 9PW.55.5.1 POZ88140 Petrotoga sibirica DSM 13575 WP 103877284 Petrotoga

WP 103067341 Petrotoga olearia

WP 103079010 Petrotoga 2572229017 Petrotoga sp. 8T1HF07.NaAc.6.1 WP 103077838 Petrotoga mexicana WP 121515358 unclassified Petrotoga 2558333798 Petrotoga sp. 9T1HF07.CasAA.8.2 WP 012209457 Petrotoga 641302858 Petrotoga mobilis SJ95