Emerging Infectious Diseases
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Vaccine to Prevent Human Papillomavirus
Resolution No. 6/20-1 ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES VACCINES FOR CHILDREN PROGRAM VACCINES TO PREVENT MENINGOCOCCAL DISEASE The purpose of this resolution is to update the resolution to reflect currently available meningococcal conjugate vaccines that can be used to prevent meningococcal disease attributable to serogroups A, C, W, and Y. VFC resolution 6/19-7 is repealed and replaced by the following: Meningococcal Conjugate Vaccines (MenACWY) Eligible Groups • Children aged 2 months through 10 years who are at increased risk for meningococcal disease attributable to serogroups A, C, W, and Y, including: o Children who have persistent complement component deficiencies (including inherited or chronic deficiencies in C3, C5-C9, properdin, factor H, or factor D) o Children taking a complement inhibitor (e.g., eculizumab [Soliris], ravulizumab [Ultomiris]) o Children who have anatomic or functional asplenia, including sickle cell disease o Children infected with human immunodeficiency virus (HIV) o Children traveling to or residing in countries in which meningococcal disease is hyperendemic or epidemic, particularly if contact with local population will be prolonged o Children identified to be at increased risk because of a meningococcal disease outbreak attributable to serogroups A, C, W, or Y • All children aged 11 through 18 years 1 Recommended Vaccination Schedule and Intervals The table below lists meningococcal conjugate vaccines currently available to prevent meningococcal disease attributable to serogroups A, C, W, and -
An Atlas of Potentially Water-Related Diseases in South Africa
AN ATLAS OF POTENTIALLY WATER-RELATED DISEASES IN SOUTH AFRICA Volume 2 Bibliography Report to the WATER RESEARCH COMMISSION by N Coetzee and D E Bourne Department of Community Health University of Cape Town Medical School WRC Report no. 584/2/96 ISBN 1 86845 245 X ISBN Set No 1 86845 246 8 1 CONTENTS VOLUME 2 BIBLIOGRAPHY 1 Introduction 2 2 Amoebiasis 3 3 Arthropod-borne viral diseases 7 4 Cholera 10 5 Diarrhoeal diseases in childhood 14 6 Viral hepatitis A and E 17 7 Leptospirosis 20 3 Pediculosis 22 9 Malaria 23 10 Poliomyelitis 29 11 Scabies 33 12 Schistosomiasis 35 13 Trachoma 39 14 Typhoid Fever 42 15 Intestinal helminthiasis 46 1. INTRODUCTION As many professionals involved in the management of water resources do not have a medical or public health background, it was thought that an explanatory bibliography of the major water related diseases in South Africa would be of use. Each section of the bibliography has (where appropriate) the following sections: 1. Aetiology 2. Transmission 3. Preventive and curative steps 4. South African data 5. References The MEDLINE data base of the national Library of Medicine, Washington DC, and the WATERLIT data base of the CSIR were searched. These were supplemented by South African journals and reports not appearing in the MEDLINE data base. 3 2. AMOEBIASIS 2.1. Aetiology The protozoan parasite Entamoeba histolytica which causes amoebiasis may exist as a hardy infective cyst or a more fragile and potentially pathogenic trophozoite (the "amoebic" form). Amoebiasis most commonly affects the colon and rectum as primary sitas of infection, with extraintestinal (most commonly liver abscesses), local or systemic, spread possible if not treated early. -
Comparison of Annual and Biannual Mass Antibiotic Administration for Elimination of Infectious Trachoma
ORIGINAL CONTRIBUTION Comparison of Annual and Biannual Mass Antibiotic Administration for Elimination of Infectious Trachoma Muluken Melese, MD, MPH Context Treatment recommendations assume that repeated mass antibiotic distri- Wondu Alemayehu, MD, MPH butions can control, but not eradicate or even locally eliminate, the ocular strains of Takele Lakew, MD, MPH chlamydia that cause trachoma. Elimination may be an important end point because of concern that infection will return to communities that have lost immunity to chla- Elizabeth Yi, MPH mydia after antibiotics are discontinued. Jenafir House, MPH, MSW Objective To determine whether biannual treatment can eliminate ocular chla- Jaya D. Chidambaram, MBBS mydial infection from preschool children and to compare results with the World Health Organization–recommended annual treatment. Zhaoxia Zhou, BA Design, Setting, and Participants A cluster-randomized clinical trial of biannual Vicky Cevallos, MT vs annual mass azithromycin administrations to all residents of 16 rural villages in the Kathryn Ray, MA Gurage Zone, Ethiopia, from March 2003 to April 2005. Kevin Cyrus Hong, BA Interventions At scheduled treatments, all individuals aged 1 year or older were Travis C. Porco, PhD, MPH offered a single dose of oral azithromycin either annually or biannually. Isabella Phan, MD Main Outcome Measure Village prevalence of ocular chlamydial infection and pres- ence of elimination at 24 months in preschool children determined by polymerase chain Ali Zaidi, MD reaction, correcting for baseline prevalence. Antibiotic treatments were performed af- Bruce D. Gaynor, MD ter sample collections. John P. Whitcher, MD, MPH Results Overall, 14 897 of 16 403 eligible individuals (90.8%) received their sched- uled treatment. -
Exposure to Holoendemic Malaria Results in Suppression of Epstein-Barr Virus-Specific T Cell Immunosurveillance in Kenyan Children
University of Massachusetts Medical School eScholarship@UMMS Population and Quantitative Health Sciences Publications Population and Quantitative Health Sciences 2007-02-15 Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children Ann M. Moormann University of Massachusetts Medical School Et al. Let us know how access to this document benefits ou.y Follow this and additional works at: https://escholarship.umassmed.edu/qhs_pp Part of the Biostatistics Commons, Epidemiology Commons, Health Services Research Commons, Immunology and Infectious Disease Commons, and the Pediatrics Commons Repository Citation Moormann AM, Chelimo K, Sumba PO, Tisch DJ, Rochford RA, Kazura JW. (2007). Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children. Population and Quantitative Health Sciences Publications. https://doi.org/10.1086/ 511984. Retrieved from https://escholarship.umassmed.edu/qhs_pp/397 This material is brought to you by eScholarship@UMMS. It has been accepted for inclusion in Population and Quantitative Health Sciences Publications by an authorized administrator of eScholarship@UMMS. For more information, please contact [email protected]. MAJOR ARTICLE Exposure to Holoendemic Malaria Results in Suppression of Epstein-Barr Virus–Specific T Cell Immunosurveillance in Kenyan Children Ann M. Moormann,1 Kiprotich Chelimo,4 Peter O. Sumba,4 Daniel J. Tisch,2 Rosemary Rochford,3 and James W. Kazura1 1Center for Global Health and Diseases and 2Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio; 3Department of Microbiology and Immunology, State University of New York Upstate Medical University, Syracuse; 4Kenya Medical Research Institute, Center for Vector Biology and Control Research, Kisumu, Kenya Background. -
Phleboviruses and the Type I Interferon Response
viruses Review Phleboviruses and the Type I Interferon Response Jennifer Deborah Wuerth and Friedemann Weber * Institute for Virology, FB10-Veterinary Medicine, Justus-Liebig University, Giessen 35392, Germany; [email protected] * Correspondence: [email protected]; Tel.: +49-641-99-383-50 Academic Editors: Jane Tao and Pierre-Yves Lozach Received: 8 May 2016; Accepted: 20 June 2016; Published: 22 June 2016 Abstract: The genus Phlebovirus of the family Bunyaviridae contains a number of emerging virus species which pose a threat to both human and animal health. Most prominent members include Rift Valley fever virus (RVFV), sandfly fever Naples virus (SFNV), sandfly fever Sicilian virus (SFSV), Toscana virus (TOSV), Punta Toro virus (PTV), and the two new members severe fever with thrombocytopenia syndrome virus (SFTSV) and Heartland virus (HRTV). The nonstructural protein NSs is well established as the main phleboviral virulence factor in the mammalian host. NSs acts as antagonist of the antiviral type I interferon (IFN) system. Recent progress in the elucidation of the molecular functions of a growing list of NSs proteins highlights the astonishing variety of strategies employed by phleboviruses to evade the IFN system. Keywords: phlebovirus; NSs protein; interferon; RIG-I; PKR 1. Introduction The family Bunyaviridae contains five genera, among which the Orthobunyavirus, Phlebovirus, Nairovirus, and Hantavirus all contain species that are pathogenic to humans and animals, while the genus Tospovirus contains -
The Emergence of Epidemic Dengue Fever and Dengue Hemorrhagic
Editorial The emergence of A global pandemic of dengue fever (DF) and dengue hemorrhagic fever (DHF) began in Southeast Asia during World War II and in the years following that con- epidemic dengue flict (1). In the last 25 years of the 20th century the pandemic intensified, with increased geographic spread of both the viruses and the principal mosquito vec- fever and dengue tor, Aedes aegypti. This led to larger and more frequent epidemics and to the emergence of DHF as tropical countries and regions became hyperendemic with hemorrhagic fever the co-circulation of multiple virus serotypes. With the exception of sporadic epidemics in the Caribbean islands, in the Americas: dengue and yellow fever were effectively controlled in the Americas from 1946 a case of failed until the late 1970s as a result of the Ae. aegypti eradication program conducted by the Pan American Health Organization (PAHO) (1, 2). This was a vertically struc- public health policy tured, paramilitary program that focused on mosquito larval control using source reduction and use of insecticides, primarily dichlorodiphenyltrichloroethane (DDT). This highly successful program, however, was disbanded in the early 1970s because there was no longer a perceived need and there were competing 1 Duane Gubler priorities for resources; control of dengue and yellow fever was thereafter merged with malaria control. Another major policy change at that time was the use of ultra-low-volume space sprays for killing adult mosquitoes (adulticides) as the rec- ommended method to control Ae. aegypti and thus prevent and control DF and DHF. Both of these decisions were major policy failures because they were inef- fective in preventing the re-emergence of epidemic DF and the emergence of DHF in the Region. -
Meeting of the Board of Scientific Counselors, Office of Infectious Diseases
MEETING OF THE BOARD OF SCIENTIFIC COUNSELORS, OFFICE OF INFECTIOUS DISEASES Centers for Disease Control and Prevention Tom Harkin Global Communications Center Atlanta, Georgia May 2–3, 2018 A one-and-a-half day, open public meeting of the Board of Scientific Counselors (BSC), Office of Infectious Diseases (OID), was held on May 2–3, 2018, at the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia. In addition to Board members and CDC staff, the meeting was attended by representatives of several public health partner organizations (appendix). The meeting included • Updates from OID, the Center for Global Health (CGH), and the National Centers for Immunization and Respiratory Diseases (NCIRD); HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP); and Emerging and Zoonotic Infectious Diseases (NCEZID) • Updates from the BSC Infectious Disease Laboratory Working Group (IDLWG) and the new OID– National Center for Environmental Health (NCEH)/Agency for Toxic Substances and Disease Registry (ATSDR) Vector-borne Diseases Workgroup • Updates on activities to address antimicrobial resistance by Veterinary Services (VS), Animal and Plant Health Inspection Service, U.S. Department of Agriculture (USDA/APHIS) and CDC • Presentations and discussion about CDC efforts to address the opioid epidemic, train the next generation of public health workers, and advance the CDC High Containment Laboratory Initiative The meeting also included a conversation with CDC Director Robert Redfield. Opening Remarks BSC Chair Ruth Lynfield, State Epidemiologist and Medical Director, Minnesota Department of Health, called the meeting to order and was joined in welcoming participants and facilitating introductions by Sonja Rasmussen, CDC Deputy Director for Infectious Diseases, and Sarah Wiley, the BSC/OID Designated Federal Official. -
Chapter 11. Phlebotomus Fever—Sandfly Fever
Chapter 11 Phlebotomus Fever—Sandfly Fever Koray Ergunay Hacettepe University Faculty of Medicine, Department of Medical Microbiology, Virology Unit, Ankara, Turkey CASE PRESENTATION During mid-August, a 27-year-old male was admitted to the emergency ward with high fever, chills, severe headache, joint pain, watery diarrhea, nausea and, vomiting, which had started the day before. The initial complete physical examination demonstrated a fever of 38.9C, generalized muscle tenderness, and multiple skin lesions suggesting insect bites on the upper left limb. Neurological examination was normal without meningeal signs. Medical his- tory revealed no previous disease of significance but an exposure to mosqui- toes during his stay at his cousin’s cottage 5 days ago. He had vomited three times during the last 24 hours. No apparent risk for infectious gastroenteritis could be identified. Laboratory evaluation demonstrated decreased leukocyte count (3.8 3 103/μL) with relative lymphocytosis, decreased platelet count (1.32 3 105/μL), elevated alanine aminotransferase (ALT, 101 U/L), aspartate aminotransferase (AST, 128 U/L), gamma glutamyl transpeptidase (GGT, 107 U/L), creatinine phosphokinase (CPK, 428 U/L), and lactate dehydroge- nase (LDH, 354 U/L) levels. Hemoglobulin, C-reactive protein, total protein, blood urea nitrogen (BUN), albumin, creatinine, prothrombin time (PT), acti- vated partial thromboplastin time (aPTT), international normalized ratio (INR), and the chest X-ray were within normal limits. The patient was trans- ferred to the infectious diseases department with the preliminary diagnosis of undifferentiated viral febrile condition, and blood and stool samples were sub- mitted for microbiological analyses. Symptomatic treatment with intravenous rehydration and anti-pyretics was initiated. -
Editorial Acquired Immunity in a Holoendemic Setting of Plasmodium Falciparum and P
University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Public Health Resources Public Health Resources 2007 EDITORIAL ACQUIRED IMMUNITY IN A HOLOENDEMIC SETTING OF PLASMODIUM FALCIPARUM AND P. VIVAX MALARIA J. Kevin Baird ALERTAsia Foundation, [email protected] Robert W. Snow University of Oxford-Wellcome Trust Collaborative Programme, Nairobi, Kenya Follow this and additional works at: http://digitalcommons.unl.edu/publichealthresources Baird, J. Kevin and Snow, Robert W., "EDITORIAL ACQUIRED IMMUNITY IN A HOLOENDEMIC SETTING OF PLASMODIUM FALCIPARUM AND P. VIVAX MALARIA" (2007). Public Health Resources. 359. http://digitalcommons.unl.edu/publichealthresources/359 This Article is brought to you for free and open access by the Public Health Resources at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Public Health Resources by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. Europe PMC Funders Group Author Manuscript Am J Trop Med Hyg. Author manuscript; available in PMC 2013 March 22. Published in final edited form as: Am J Trop Med Hyg. 2007 June ; 76(6): 995–996. Europe PMC Funders Author Manuscripts EDITORIAL ACQUIRED IMMUNITY IN A HOLOENDEMIC SETTING OF PLASMODIUM FALCIPARUM AND P. VIVAX MALARIA J. KEVIN BAIRD* and ROBERT W. SNOW ALERTAsia Foundation, Jakarta, Indonesia; Kenya Medical Research institute University of Oxford-Wellcome Trust Collaborative Programme, Nairobi, Kenya Most of what we presume to understand of naturally acquired immunity to Plasmodium falciparum malaria comes from studies in sub-Saharan Africa. The virtual absence of P. vivax malaria from most of that region leaves three important questions not addressed: 1) What is naturally acquired immunity to P. -
Emerging Viral Infections Phleboviruses
Emerging viral infections Phleboviruses © by author Anna Papa National ReferenceESCMID Centre Online for Arboviruses Lecture and Hemorrhagic Library Fever viruses Aristotle University of Thessaloniki, Greece Main vectors of phleboviruses: phlebotomine sandflies © by author Etymologia. Phlebotomus: from the Greek words phleboESCMID + tomi=opening Online a vein Lecture Library TAXONOMY Phleboviruses: arthropod-borne RNA viruses Genus Phlebovirus - Family Bunyaviridae Cause to humans symptoms ranging from short self limiting fever to encephalitis and fatal hemorrhagic fever. 70 antigenically distinct serotypes: • Sandfly Fever group – 55 serotypes (most transmitted by sandflies, few by mosquitoes, e.g. Rift Valley fever) •Uukuniemi group – 13 serotypes (transmitted by ticks). • Severe fever and thrombocytopenia syndrome (SFTS) virus (transmitted by ticks). © by author 9 antigenic complexes including 37 classified viruses. Species differentiation based on a 4-fold difference in neutralization tests. High rate of genetic reassortment of the M segment: relying only on neutralizationESCMID or hemagglutination Online Lectureinhibition assays Library is not enough. VIRION Enveloped, spherical. Diameter 80-120 nm. Glycoproteins serve as neutralizing and hemagglutinin-inhibiting antibody targets and are exposed to selective pressure. GENOME Segmented negative- stranded RNA genome. Encodes for © by author 6 proteins. S : N protein and a NSs. Uses an ambisense coding strategy ESCMIDM Online : precursor of Lecturethe viral glycoproteins Library Gn and Gc , and NSm. L : viral RNA polymerase. Phlebotomine sandflies (Psychodidae) • > 500 different species • Widely distributed in Med countries from May to September. The number increases after rainy season. • Abundant in peri-urban and rural environments, close to domestic animals and human populations. • A cool, shaded, slightly damp The sandfly becomes infected environment is ideal for the sandfly life. -
Taxonomy of the Order Bunyavirales: Update 2019
Archives of Virology (2019) 164:1949–1965 https://doi.org/10.1007/s00705-019-04253-6 VIROLOGY DIVISION NEWS Taxonomy of the order Bunyavirales: update 2019 Abulikemu Abudurexiti1 · Scott Adkins2 · Daniela Alioto3 · Sergey V. Alkhovsky4 · Tatjana Avšič‑Županc5 · Matthew J. Ballinger6 · Dennis A. Bente7 · Martin Beer8 · Éric Bergeron9 · Carol D. Blair10 · Thomas Briese11 · Michael J. Buchmeier12 · Felicity J. Burt13 · Charles H. Calisher10 · Chénchén Cháng14 · Rémi N. Charrel15 · Il Ryong Choi16 · J. Christopher S. Clegg17 · Juan Carlos de la Torre18 · Xavier de Lamballerie15 · Fēi Dèng19 · Francesco Di Serio20 · Michele Digiaro21 · Michael A. Drebot22 · Xiaˇoméi Duàn14 · Hideki Ebihara23 · Toufc Elbeaino21 · Koray Ergünay24 · Charles F. Fulhorst7 · Aura R. Garrison25 · George Fú Gāo26 · Jean‑Paul J. Gonzalez27 · Martin H. Groschup28 · Stephan Günther29 · Anne‑Lise Haenni30 · Roy A. Hall31 · Jussi Hepojoki32,33 · Roger Hewson34 · Zhìhóng Hú19 · Holly R. Hughes35 · Miranda Gilda Jonson36 · Sandra Junglen37,38 · Boris Klempa39 · Jonas Klingström40 · Chūn Kòu14 · Lies Laenen41,42 · Amy J. Lambert35 · Stanley A. Langevin43 · Dan Liu44 · Igor S. Lukashevich45 · Tāo Luò1 · Chuánwèi Lüˇ 19 · Piet Maes41 · William Marciel de Souza46 · Marco Marklewitz37,38 · Giovanni P. Martelli47 · Keita Matsuno48,49 · Nicole Mielke‑Ehret50 · Maria Minutolo3 · Ali Mirazimi51 · Abulimiti Moming14 · Hans‑Peter Mühlbach50 · Rayapati Naidu52 · Beatriz Navarro20 · Márcio Roberto Teixeira Nunes53 · Gustavo Palacios25 · Anna Papa54 · Alex Pauvolid‑Corrêa55 · Janusz T. Pawęska56,57 · Jié Qiáo19 · Sheli R. Radoshitzky25 · Renato O. Resende58 · Víctor Romanowski59 · Amadou Alpha Sall60 · Maria S. Salvato61 · Takahide Sasaya62 · Shū Shěn19 · Xiǎohóng Shí63 · Yukio Shirako64 · Peter Simmonds65 · Manuela Sironi66 · Jin‑Won Song67 · Jessica R. Spengler9 · Mark D. Stenglein68 · Zhèngyuán Sū19 · Sùróng Sūn14 · Shuāng Táng19 · Massimo Turina69 · Bó Wáng19 · Chéng Wáng1 · Huálín Wáng19 · Jūn Wáng19 · Tàiyún Wèi70 · Anna E. -
Waterborne Disease Risk Assessment Program 2019 Annual Report
New York City Department of Health & Mental Hygiene Bureau of Communicable Disease & New York City Department of Environmental Protection Bureau of Water Supply Waterborne Disease Risk Assessment Program 2019 Annual Report March 2020 Prepared in accordance with Section 8.1 of the NYSDOH 2017 NYC Filtration Avoidance Determination i TABLE OF CONTENTS TABLE OF CONTENTS ................................................................................................................. i LIST OF TABLES ........................................................................................................................ iii LIST OF FIGURES ........................................................................................................................ iv LIST OF ACRONYMS ................................................................................................................... v ACKNOWLEDGMENTS .............................................................................................................. vi EXECUTIVE SUMMARY .......................................................................................................... vii 1. INTRODUCTION .................................................................................................................... 1 2. DISEASE SURVEILLANCE .................................................................................................. 1 2.1 Giardiasis .......................................................................................................................... 1