BIOGRAPHICAL SKETCH Claudia Neuhauser Distinguished McKnight University and HHMI Professor Associate Vice President for Research Director, Research Computing University of Minnesota Twin Cities

Professional Preparation

Undergraduate – 1988. Diplom, Mathematics, Heidelberg (Germany). Field of concentration: Mathematics. Graduate – 1990. Ph.D., Mathematics, Cornell University. Graduate honors: MSI Graduate Fellow (Cornell University).

Appointments 2014- University of Minnesota, Twin Cities • Associate Vice President for Research (July 2016-current) • Director, Research Computing (November 2015-current) • Director (University-wide), University of Minnesota Informatics Institute (January 2014-present) • Director of Graduate Studies for Biomedical Informatics and Computational Biology (July 2008-2017) • Director (University-wide), Minnesota Supercomputing Institute (October 2015- present) [Interim Director, Minnesota Supercomputing Institute (April 2015-October 2015)] • Professor, Ecology, Evolution and Behavior (40%), Biochemistry, Molecular Biology, Biophysics (30%), Computer Science and Engineering (30%) (January 2014- present) 2008-2013 University of Minnesota, Rochester, MN • Vice Chancellor for Academic Affairs and Student Development (July 2013- December 2013) • Vice Chancellor for Academic Affairs (July 2008-June 2013) • Director of Graduate Studies for Biomedical Informatics and Computational Biology (July 2008- December 2013) • Director, Center for Learning Innovation (July 2008-June 2013) • Professor (July 2008-December 2013) 2007- 2008 University of Minnesota, Rochester, MN • Director, Center for Learning Innovation (January 2007-June 2008) 2001- 2008 University of Minnesota, Twin Cities, MN, Department of Ecology, Evolution and Behavior • Head (Fall 2005-Spring 2008) • Head and Director of Graduate Studies (Spring 2004-Summer 2005) • Interim Head and Director of Graduate Studies (Fall 2003) • Director of Graduate Studies (Spring 2002-Summer 2003) • Professor (2001-June 2008) 2001-2002 University of California, Davis, Section of Evolution and Ecology and Department of 1 Mathematics • Professor (Fall 2001-Winter 2002). 1996- 2001 University of Minnesota, Twin Cities, MN, School of Mathematics • Professor (Fall 2000-Fall 2001) • Associate Professor (Fall 1996-Spring 2000) 1992-1998 University of Wisconsin, Madison, WI, Department of Mathematics • Associate Professor (Fall 1995-Spring 1998) • Assistant Professor (Fall 1993- Spring1995) • Visiting Assistant Professor (Fall 1992-Spring 1993) 1990-1994 University of Southern California, Department of Mathematics • Assistant Professor (Fall 1990-Spring 1994)

Graduate Education Privileges University of Minnesota • Biomedical Informatics and Computational Biology • Ecology, Evolution and Behavior • Conservation Biology • Mathematics Mayo Graduate School • Temporary Graduate Faculty Privileges: March 2014-August 2016

Grants Minnesota Partnership for Biotechnology and Medical Genomics Grant. (3-Dimensional, Nanoscale Resolution Microscopy for Understanding Human Disease Processes); PI, $1,059,320; collaborative grant with Dr. Jeffrey Salisbury, Mayo Clinic (November 2016-October 2019). NSF EAGER GERMINATION: From 0 to 2: PI ($92,953; 1% effort). April 2016-March 2017. CHS: Small: Collaborative Research: Optimizing the Human-Machine System for Citizen Science: co-PI ($359,560; 1% effort). July 2016-June 2018. Minnesota Partnership for Biotechnology and Medical Genomics Grant. (Predicting response and resistance to proteasome inhibitors n multiple myeloma); co-Investigator; PI: Brian Van Ness ($850,000; advising role). February 1, 2015-January 31, 2017. BD2K: Big Data Coursework for Computational Medicine: PI: Pathak, J., Ph.D.; Role: co-PI. 1 R25 HG008144-01. September 2014 – August 2017. (6% effort on University of Minnesota subaward; $60,780 for 9/29/2014 to 5/31/2015) Measuring multiprotein assemblies that drive biological signals: PI: Schrum, A., Ph.D.; NIGMS 1R01GM103841-01A1. April 2012-March 2018. (6% effort on University of Minnesota subaward; $21,180 for April 2013-March 2014) Molecular imaging and system dynamics of tumor virotherapy: PI: Dingle, D., M.D./Ph.D.; co-PI; National Cancer Institute: R01 CA 164241-0; $2,663,995 (total cost) September 2011 – August 2016 Clinical and Translational Science Award (CTSA); PI: Bruce R. Blazer, M.D.; Consultant (0.6 months; 2011). Minnesota Partnership for Biotechnology and Medical Genomics Grant. (Applying network theory to optimize cancer virotherapy); co-PI, $450,000; collaborative grant with Dr. David Dingli, Mayo Clinic, and Dr. Zeljko Bajzer, Mayo Clinic; January 2010-December 2011.) NSF-DEB (The Evolution of Pathogen Virulence in Experimental Metapopulations; co-PI, $184,996; PI: Antony Dean; collaborative grant with Ben Kerr, PI, University of Washington: $413,750; July 2007 – July 2010) Howard Hughes Medical Institute Professor Grant. $1,000,000. September 2006-August 2010.

2 NSF IGERT (Non-equilibrium dynamics across space and time: a common approach for engineers, earth scientists, and ecologists; (P.I. until August 2008; co-PI August 2008-January 2009), $2.8 Million; August 2005 – July 2010) NSF-DEB (Ecological Stoichiometry and the Relevance of Prokaryotic Heterotroph Biodiversity; co-PI, $500,000; PI: Cotner, other co-PI: LaPara; July 2005 – June 2008) NSF Biocomplexity Grant (Ecology and Evolution of Perturbed Systems; P.I. $ 2.9 Million; September 2000 – August 2007) NSF UBM Supplement (Interdisciplinary Training for Undergraduates in Biological and Mathematical Sciences: Aquatic Food Web Modeling; P.I. $80,000; September 2003-May 2005) Individual NSF grants (P.I.; June 1991 - May 2005) USDA Forest Service Grant (co-P.I.; September 1994 - October 1995)

Awards and Honors

American Mathematical Society Fellow (2012) Minnesota’s Tekne Award EdTech Category (2012) AAAS Fellow (Mathematics) (2011) Invited speaker, International Congress of Mathematicians, Hyderabad, India (2010) Bruce Alberts Award for Excellence in Science Education from the American Society for Cell Biology (awarded as part of the BioQUEST Curriculum Consortium) (2010) Distinguished McKnight University Professor (2007) HHMI Professor (2006) Best Director of Graduate Student Award, University of Minnesota (2005) Horace T. Morse—University of Minnesota Alumni Award for Outstanding Contributions to Undergraduate Education (2004) CBS Dagley-Kirkwood Award for Undergraduate Education (2003) Sloan Fellowship (September 1994 - August 1996) MSI Graduate Fellowship (September 1989-May 1990)

Professional Activities

Service

• American Association for the Advancement of Science: Electorate Nominating Committee (ENC) of the Section of Mathematics (02/2017-02/2020) • Intelligence Science and Technology Experts Group (National Academies of Sciences, Engineering, and Medicine) (2015-current) • External Advisory Board of QUBES (Quantitative Undergraduate Biology Education and Synthesis (2014-current) • American Association for the Advancement of Science: Representative to the Section Committee on Mathematics (A, IMS representative) (2014-2017) • Member of the National Advisory Committee of The Statistical and Applied Mathematical Sciences Institute (SAMSI) (2014-current) • Reinvention Center Executive Board, Chair (2013-2016); Past President (2016-2017) • Member of the Board of Trustees of the Mathematical Biosciences Institute, The Ohio State University (2012-2015) • External Advisory Board for the HHMI “National Experiment in Undergraduate Science Education” project (May 2011-2014) 3 • American Mathematical Society Committee on Science Policy Member at Large (Feb 2011- January 2014) • Board of Directors of The Society for Mathematical Biology (2010-2014) • U.S. Delegate to the International Mathematical Union General Assembly, Bangalore, India (2010) • Board on Mathematical Sciences and Their Applications of the National Academy (2009-2012, 2012-2015) • Selection Committee, Mathematical Biosciences Institute (2009-2013) • Reinvention Center Executive Board (2009-current) • Scientific Advisory Board for the BioEnergy Science Center, Oak Ridge National Laboratory (2008-2009) • AAMC-HHMI Scientific Foundation for Future Physicians Committee (2007-2009) • American Association for the Advancement of Science Member-at-Large of the Section Committee on Mathematics (A) (2007-2011) • National Academy of Sciences’ Committee for the Review of the Department of Energy’s Genomics: GTL (2005-06) • National Academy of Sciences’ Committee for Mathematical Sciences Research for Department of Energy’s Computational Biology (2004-05) • Member of the Board of Governors of the Mathematical Biosciences Institute, The Ohio State University (2003-2006) • Member of the External Advisory Board of the Graduate and Postdoctoral Training in Probability Theory and its Applications at Cornell University (2003-2010) • Institute for Mathematical Statistics Selection Committee for Wald and Rietz Lectures (2001- 2003) • Society for Mathematical Biology Educational Subcommittee (1999-2007)

Synergistic Activities

Academic, Administrative and Department Service at the University of Minnesota • Director, Research Computing (November 2015-current) • Director, Minnesota Supercomputing Institute (November 2015-current) • Director (University-wide), University of Minnesota Informatics Institute (January 2014-current) • Interim Director, Minnesota Supercomputing Institute (March 2015-November 2015) • Vice Chancellor for Academic Affairs and Student Development, University of Minnesota Rochester (July 2013-December 2013) • Vice Chancellor for Academic Affairs, University of Minnesota Rochester (July 2008-June 2013) • Director of Graduate Studies in Biomedical Informatics and Computational Biology (July 2008- July 2017) • Director, Center for Learning Innovation, University of Minnesota Rochester (January 2008-July 2013) • Department Head in Ecology, Evolution and Behavior (EEB) (Spring 2004-Spring 2008) • Interim Department Head in Ecology, Evolution and Behavior (EEB) (Fall 2003) • Director of Graduate Studies in Ecology, Evolution and Behavior (Spring 2002-Summer 2005) • Curriculum Subcommittee School of Mathematics (2002-2004) • EEB Seminar Committee (2002-2003) • EEB Ad Hoc Committee for Adjunct Faculty (chair) (2001-2002) • EEB Curriculum Committee (co-chair) (2001-2002)

4 • EEB Curriculum Committee (2000-2001) • EEB Postdoctoral Selection Committee (2000-2001) • Curriculum Committee School of Mathematics (1998-2000)

Other Service at the University of Minnesota • Core Research Infrastructure Accountability Committee (2015-current) (OVPR) • Security Advisory Committee (2014-current) • Undergraduate Research Advisory Committee (OVPR and Provost Office) (2014-current) • Research Core Infrastructure Committee (2014-15) (OVPR) • Unizin (2014-2016) • Accelerate Transfer of Knowledge Cornerstone Committee (Strategic Planning: OVPR) (2014- 2015) • Enhance Research Excellence Cornerstone Committee (Strategic Planning: OVPR) (2014-2015) • Research Data Management Policy (chair) (2014) • Minnesota Supercomputing Institute Director’s Advisory Committee (2014-2015) • Allied Health Workgroup (2013) • Faculty Council on Academic Technology (2012-2013) • Graduate Student Learning Outcomes Assessment Committee (2012-2015) • Executive IT Oversight Committee (2011-2013) • Technology Enhanced Learning (TEL) Council (2011-2012) • Provost Advisory Online Education Committee (2011) • Academic Technology Advisory Committee (2010-2013), co-chair (2011-2012) • Course Management System (CMS) Transition, Steering Committee (2010-2012) • AHC Review Steering Committee (2011) • Graduate Assistant Financing Task Force (2010-2011) • Bologna Advisory Group (2010-2014) • Challenge Curriculum Working Group (2009-2011) • Research and Scholarship Advisory Committee (Office of the Vice President for Research, 2007- 2009) • Search Committee for the Chancellor of the University of Minnesota Rochester (2007) • Chair Provost’s Advisory Committee for the Institute for the Advancement of Science and Technology (2006-2007) • Provost's Writing-Enriched Curriculum Advisory Committee (2006-2008) • Member of the Long-Range Planning Committee for MSI Support of Computation in the Biosciences (2006-2007) • Chair Hiring Committee for Director of Center for Bioinformatics and Computational Biology (2006-2007) • Planning Committee for Collaboration between UMN and Rochester (2006-2008) • Senate Committee on Educational Policy (2005-2008) • Co-chair Task Force on Reconfiguring Sciences and Engineering (2005-2006) • CBS Curriculum Task Force (2003-2005) • Graduate School Curriculum Review Committee (2003-2005) • Graduate School Fellowship Committee (2003-2005) • Graduate School Fulbright Committee (2002)

Service to NSF • NSF UBM Panel (2005-2007) 5 • NSF Site Visit to proposed sites for Undergraduate Research Centers (NSF Chemistry Division) (two sites) (2005) • NSF Site Visits to proposed sites for Undergraduate Research Centers (NSF Chemistry Division) (two sites) (2004) • Committee of Visitors for NSF Division of Mathematical Sciences Review (2004) • Chair of NSF National Center for Ecological Analysis and Synthesis Site Visit Committee (2004) • Member of the NSF Mathematical and Physical Sciences and Education and Human Resources Subcommittee (2003-2005) • Member of the NSF Mathematical and Physical Sciences Advisory Committee (2002-2005) • NSF Postdoctoral Panel in Mathematics (1999-2002) • NSF Evolutionary Synthesis Workshop 2002 • Numerous other NSF panels

Service to NIH • NIH Genetics Study Section (2001-2004)

Associate Editor • Theoretical Population Biology—Associate Editor (2002-current) • The Annals of Applied Probability (1997-2002) • Proceedings of the American Mathematical Society (1999-2002) • Journal of Mathematical Biology (2001-2006) • Bulletin of Mathematical Biology (2002-2007) • Methodology and Computing in Applied Probability (2002-2010) • Alea (Latin American Journal of Probability and Mathematical Statistics) (2005-2010) • Journal of Biological Dynamics (2006-2010) • Editorial Board BioQUEST Curriculum Consortium (2006-current)

Workshop Organization (prior to 2007)

1994 co-organized workshop on catalysis at the Institute of Mathematics and Its Applications (IMA) 1999 organizer of IMA workshop on Local Interaction and Global Phenomena in Vegetation and Other Systems 1999 co-organized two-week workshop at the NATO Advanced Studies Institute on Mathematical Problems Arising from Biology (Toronto) 2000 vice-chair of the Gordon Research Conference on Theoretical Biology and Biomathematics 2000-05 member of the Committee for Conferences on Stochastic Processes (committee of the Bernoulli Society for Mathematical Statistics and Probability) 2002 chair of the Gordon Research Conference on Theoretical Biology and Biomathematics 2003 organizer of session at the Annual IMS Conference 2003 co-organizer of IMA workshop on Networks and the Population Dynamics of Disease Transmission 2003 organizing committee of the SIAM Life Sciences Conference 2004 2004-06 organizing committee for the 2005-2006 year on Evolution and Ecology at the Mathematical Biosciences Institute, The Ohio State University 2006 co-organizer of the Mathematical Biosciences Institute Workshop on Spatial Ecology, The Ohio State University

6 Member of American Association for the Advancement of Science, American Mathematical Society, Society for Mathematical Biology, Institute for Mathematical Statistics, Mathematical Association of America

Publications (* indicates authors’ list in alphabetical order)

1. C. Neuhauser 1990. An Ergodic Theorem for Schlögl Models with Small Migration. Probab. Theory and Rel. Fields 85: 27-32. 2. Neuhauser 1990. One Dimensional Stochastic Ising Models with Small Migration. Ann. of Probab. 18:1539-1546. 3*. R. Durrett and C. Neuhauser 1991. Epidemics with Recovery in d=2. Annals of Appl. Probab. 1: 189- 206. 4. C. Neuhauser 1992. Ergodic Theorems for the Multitype Contact Process. Probab. Theory and Rel. Fields 91:467-506. 5*. M. Bramson and C. Neuhauser 1994. A Catalytic Surface Reaction Model. Journal of Computational and Applied Mathematics 40:157-161. 6*. C. Neuhauser and A. Sudbury 1993. The Biased Annihilating Branching Process. Advances of Applied Probability 25:24-38. 7*. R. Durrett and C. Neuhauser. 1994. Particle systems and reaction-diffusion equations. Annals of Probability 22:289-333. 8. C. Neuhauser 1994. Long Range Sexual Reproduction Process. Stochastic Processes and their Applications 53:193-220. 9*. Bramson and C. Neuhauser 1994. Survival of One-Dimensional Cellular Automata under Random Perturbations. Annals of Probab. 22:244-263. 10. Neuhauser 1995. A Poisson Approximation for Sequence Comparisons with Insertions and Deletions. Annals of Statistics 22:1603-1629. 11*. H. Kang, S. Krone, and C. Neuhauser 1995. Stepping stone model with extinction and recolonization. Annals of Applied Probability 5:1025-1060 12. C. Neuhauser, H. Kang, and S. Krone 1995. A Note on a Stepping Stone Model with Extinction and Recolonization. IMA proceedings, vol. 87, Progress in Population Genetics and Human Evolution, eds. Peter Donnelly and Simon Tavaré. Pp. 299-307. 13. C. Neuhauser 1996. A Phase Transition for the Distribution of Matching Blocks. Combinatorics, Probability and Computing 5:139--159. 14*. J.L. Lebowitz, C. Neuhauser, and K. Ravishankar 1996. Dynamics of a Spin Exchange Model. Stochastic Processes and their Applications 64:187--208. 15. C. Neuhauser and S. Krone 1997. The Genealogy of Samples in Models with Selection. Genetics 145:519-534. 16*. R. Durrett and C. Neuhauser 1997. Coexistence Results for Some Competition Models. The Annals of Applied Probability 7:10--45. 17*. M. Bramson and C. Neuhauser 1997. Coexistence for a Catalytic Surface Reaction Model. The Annals of Applied Probability 7:565-614. 18*. S. Krone and C. Neuhauser 1997. Ancestral Processes with Selection. Theoretical Population Biology 51:210--237. 19. C. Neuhauser 1998. Habitat destruction and competitive coexistence in spatially explicit models with local interactions. Journal of Theoretical Biology 139:445-463 20. C. Neuhauser 1999. The ancestral graph and gene genealogy under frequency-dependent selection. Theoretical Population Biology 56:203--214. 21*. C. Neuhauser and S. Pacala 1999. An explicitly spatial version of the Lotka-Volterra model 7 with interspecific competition. Annals of Applied Probability 9:1226-1259 22. C. Neuhauser 1999. The role of explicit space in plant competition models. In Perplexing Problems in Probability. Festschrift in Honor of Harry Kesten. Eds. M. Bramson and R. Durrett. Pp. 355--372. Birkhäuser. 23. S. Pletcher and C. Neuhauser 2000. Biological aging - Criteria for modeling and a new mechanistic model. International Journal of Modern Physics, C, 11:525--546. 24*. S. Krone and C. Neuhauser 2000. A spatial model for range-dependent succession. Journal of Applied Probability 37:1044--1060. 25. C. Neuhauser 2000. Mathematical Models in Population Genetics. In Handbook of Statistical Genetics. Pp. 153-178. Wiley. 26. S. Tavaré and C. Neuhauser 2001. The coalescent. Encyclopedia of Genetics. (5 pages). 27. C. Neuhauser 2001. Mathematical Challenges in Spatial Ecology. Notices of the American Mathematical Society 48:1304--1314. 28*. Ayati and C. Neuhauser 2001. A Markov embedding approximation for a stochastic model with an exogeneous disturbance. Methodology and Computing in Applied Probability. 29. P. Chesson, S. Pacala, and C. Neuhauser 2002. Environmental niches and ecosystem functioning. In Biodiversity and Ecosystem Functioning. Pp. 213-245. Princeton. 30. P. Chesson and C. Neuhauser 2002. Is aggregation really a coexistence mechanism? Trends of Ecology and Evolution. 31. C. Neuhauser 2002. Effects of Local Interactions on Stability. Theoretical Population Biology 42:297- 308 32. A. Dean, C. Neuhauser, B. Golding, and E. Grenier 2002. The Pattern of Amino-Acid Replacements in α/β-Barrels. Molecular Biology and Evolution 19:1846-1864. 33*. K. Anderson and C. Neuhauser 2002. Patterns in spatial simulations – are they real? Ecological Modelling 155:19-30. 34. B. Bolker, S.W. Pacala, and C. Neuhauser 2003. Spatial dynamics in lattices, metapopulations, and point processes: what do we really know about spatial competition? American Naturalist 162: 135- 148. 35. C. Neuhauser, D.A. Andow, G. Heimpel, G. May, R. Shaw, and S. Wagenius 2003. Community Genetics – A Synthesis of Community Ecology and Population Genetics. Ecology 84: 545-558. 36*. P. Slade and C. Neuhauser 2003. Non-neutral Genealogical Structure and Algorithmic Advancements of the Ancestral Selection Graph. Comments on Theoretical Biology 8: 255-278. 37. L.G. Perry, C. Neuhauser, and S.M. Galatowitsch. 2003. Founder control and coexistence in a simple model of asymmetric competition for light. Journal of Theoretical Biology 222: 425-436. 38. G. Heimpel, C. Neuhauser, and M. Hoogendoorn. 2003. Effects of parasitoid fecundity and host resistance on indirect interactions among hosts sharing a parasitoid. Ecology Letters 6: 556-566. 39. C. Neuhauser and J. Fargione. 2004. A mutualism-parasitism continuum model and its application to plant-mycorrhizae interactions. Ecological Modelling 177: 337-352 40. C. Neuhauser and K. Fowler. 2004. Recommended Resources in Mathematical Biology. Pp 301-326. Chapter 14 in Using the Mathematics Literature. Marcel Deker. 41. G.E. Heimpel, C. Neuhauser. D.A. Andow. 2005. Natural enemies and the evolution of resistance to transgenic insecticidal crops by pest insects: the role of egg mortality. Environmental Entomology (Forum). 34(3): 512-526. 42*. N. Lanchier and C. Neuhauser. 2006. Stochastic spatial models of host-pathogen and host-mutualist interactions I. Annals of Applied Probability 16: 448-474. 43*. N. Lanchier and C. Neuhauser. 2006. A spatially explicit model for competition among specialists and generalists in a heterogeneous environment. Annals of Applied Probability 16: 1385-1410. 44. B. Kerr, C. Neuhauser, B.J.M. Bohannan, and A.M. Dean. 2006. Local migration promotes competitive restraint in a host-pathogen ‘tragedy of the commons’. Nature 442: 75-78. 8 45. S. Wagenius, E. Lonsdorf, and C. Neuhauser. 2007. Patch aging and the double-Allee effect of self- incompatibility for plants in fragmented habitat or The effect of mating system on demography and extinction rates in fragmented habitat. American Naturalist 169: 383-397. 46*. N. Lanchier and C. Neuhauser. 2007. Voter model and biased voter model in heterogeneous environment. Journal of Applied Probability 44: 770-787. 47. E.K. Hall, C. Neuhauser, and J.B. Cotner. 2008 Toward a mechanistic understanding of how natural bacterial communities respond to changes in temperature in aquatic ecosystems. The ISME Journal. February 2008. doi: 10.1038/ismej.2008.9. 48*. N. Lanchier and C. Neuhauser. 2009. Spatially explicit, non-Mendelian diploid model. Annals of Applied Probability 19: 1880-1920. 49. M. Altun, M.D. Riedel, C. Neuhauser. Nanoscale digital computation through percolation. DAC 2009: 615-616. 50*. N. Lanchier and C. Neuhauser. 2010. Stochastic spatial models of host-pathogen and host-mutualist interactions II. Stochastic Models 26: 399-430. 51. C. Neuhauser. 2010. Coevolution in Spatial Habitats. Proceedings of the International Congress of Mathematicians, Hyderabad, India, 2010. 52*. C. Neuhauser and K. Weber. 2010. Student Success Coach: Creating a Developmental and Academic Support Model. Changing Times: New Opportunities for Student Services. 53*. C. Neuhauser and E. Stanley. 2011. The p and the Peas: An Intuitive Modeling Approach to Hypothesis Testing. In “Mathematical Modeling of Natural Phenomena,” vol 6(6): 76-95. 54. C. Neuhauser. 2012. Commentary: The Role of Integration and Abstraction in Complex Systems Thinking across Multiple Contexts. Geological Society of America Special Papaers 486, 121-122. 55. N. Beckman, C. Neuhauser, and H.C. Muller-Landau. 2012. The interacting effects of clumped seed dispersal and distance- and density-dependent natural enemy attack on seedling recruitment patterns. Journal of Ecology 100(4): 862-873. 56. C. Neuhauser. 2013. Modeling Nature and the Nature of Modeling—an Integrative Modeling Approach. Undergraduate Mathematics for the Life Sciences: Models, Processes, and Directions. Glen Ledder, Jenna P. Carpenter, and Timothy D. Comar, Eds. The Mathematical Association of America. 57. Cradic, Kendall; Murphy, Stephen; Drucker, Travis; Sikkink, Robert; Eberhardt, Norman; Neuhauser, Claudia; Vasmatzis, George; Grebe, Stefan. 2014. A simple method for gene phasing using mate pair sequencing. BMC Medical Genetics 15:19 58. Cradic, Kendall; Murphy, Stephen; Sikkink, Robert; Neuhauser, Claudia; Vasmatzis, George; Grebe, Stefan. 2015. Clinical Validation of a Haplotyping Method with Next Generation Sequencing. Clinical Chemistry 61:2, 430-431. 59. J.D. Cooper, C. Neuhauser, T. Dean, and B. Kerr. 2015. Tipping the mutation-selection balance: Limited migration increases the frequency of deleterious mutants. Journal of Theoretical Biology, 380: 123-133. 60. S.E.P. Smith, S.C. Neier, B.K. Reed, R.R, Davis, D. Gil, J.P, Sinnwell, J.E. Eckel-Passow, G.F. Sciallis, C.N. Wieland, R.R. Torgerson, Z.Chen, J.McClusky, S.R. Burrows, C. Neuhauser, A.G. Schrum. Multiplex matrix network analysis of physiologic protein complexes in the human TCR signalosome. 2016. Science Signaling 439 rs7 (DOI: 10.1126/scisignal.aad7279) 61. Brian Herman and Claudia Neuhauser. Is it time for a new model to fund science research in higher education? The Conversation. 2016. (online: https://theconversation.com/is-it-time-for-a- new- model-to-fund-science-research-in-higher-education-63691) (not peer-reviewed) 62. Shulan Tian; Huihuang Yan; Claudia Neuhauser; Susan Slager. A framework for accurate variant discovery in highly divergent regions. 2016. BMC Genomic 17:703. (https://doi.org/10.1186/s12864- 016-3045-z) 63. K. VanderWaal, R. Morrison, C. Neuhauser, C. Vilalta, and A. Perez. Translating big data into smart 9 data for veterinary epidemiology. 2017. Frontiers in Veterinary Science. 17 July 2017. (https://doi.org/10.3389/fvets.2017.00110)

Submitted 64. A. D. Scheid, V. P. Van Keulen, S. J. Felts, S. C. Neier, S. Middha, A. A. Nair, R. W. Techentin, B. K. Gilbert, J. Jen, C. Neuhauser, Y. Zhang, L. R. Pease. Structured human immune variability reveals immune phenotypes and baseline response determinants. Submitted to The Journal of Immunology. 65. A. Clark and C. Neuhauser. Harnessing Uncertainty to Approximate Mechanistic Models. Submitted to Theoretical Population Biology. 2017. 66. Mi-Yeon Jung, Chetan P. Offord, Matthew K. Ennis, Iris Kemler Cattaneo, Claudia Neuhauser, and David Dingli. In vivo estimation of oncolytic virus populations within tumors. Submitted to Cancer Research. 67. Kemler, Iris, M.K. Ennis, C. Neuhauser, and D. Dingli. In vivo imaging of oncolytic measles virus propagation with single cell resolution. Submitted to Cell Reports. 68. Steven C. Neier, Stephen E. P. Smith, Alejandro Ferrer, Katelynn M. Wilton, Tessa R. Davis, Zhenjun Chen, James McCluskey, Scott R Burrows, Jamie Rossjohn, Dietmar J. Kappes, Mark A. Daniels, Claudia Neuhauser, Diana Gil, Adam G Schrum. The proximal αβ TCR signalosome instructs thymic selection through a quantitative protein interaction network. Submitted to Science Immunology.

In Preparation 69. Berg, D.R., C.P. Offord, I. Kemler, M.K. Ennis, L. Chang, G. Paulik, Z. Bajzer, C. Neuhauser, and D. Dingli. In vitro and in silico multidimensional modeling of oncolytic tumor virotherapy dynamics. 70. C. Neuhauser and G. Vasmatzis. Rapid Detection of Copy Number Variants.

Posters Not tracked on CV.

Books C. Neuhauser 2000. Calculus for Biology and Medicine. Prentice Hall. (766 pages) C. Neuhauser 2001. Solution Manual for Calculus for Biology and Medicine. (Instructor's Manual and Student's Manual). Prentice Hall. C. Neuhauser 2003. Calculus for Biology and Medicine. 2nd edition. Prentice Hall. (822 pages) C. Neuhauser 2004. Solution Manual for Calculus for Biology and Medicine, 2nd edition. (Instructor's Manual and Student's Manual). Prentice Hall. C. Neuhauser 2004. Modeling Nature and the Nature of Modeling. Preprint. C. Neuhauser 2004. Matemáticas para Ciencias. Spanish Translation of Calculus for Biology and Medicine. 2nd edition. Prentice Hall. (990 pages) T. Barr and C. Neuhauser 2006. Calculus. Prentice Hall. (939 pages) C. Neuhauser 2010. Calculus for Biology and Medicine. 3rd edition. Prentice Hall. (782 pages) C. Neuhauser and M. Roper. 2018. Calculus for Biology and Medicine. 4th edition. Prentice Hall. (848 pages) Thesis Advisor and Postgraduate-Scholar Sponsor

Graduate students (past) – Christopher Klausmeier (Ph.D., 2000, EEB), Martin O’Hely (Ph.D., 2000, Mathematics), Jeannette Martinez (M.S., 2004, EEB), Stephanie Potoka (M.S., 2005, Mathematics), Cheng-Heng (Jack) Hu (Ph.D., 2006, Conservation Biology), Anne-Marie Hoskinson (Ph.D., 2006, Conservation Biology, co-advisor) Chris Clark (Ph.D., 2007, EEB, co- 10 advisor), Noelle Beckman (Ph.D., 2010, EEB, co-advisor), Asha Nair (M.S., 2012, BICB), Raymond Moore (M.S., 2012, BICB, co-adviser), Ruhi Rai (M.S., 2013, BICB, co-adviser), Timothy Kline (Ph.D., 2013, BICB, co-adviser), Adrienne Grzenda (M.S., 2014, BICB, co- adviser), Sumit Middha (Ph.D., 2014, BICB, co-adviser), Cen Ling (M.S., 2014, BICB, co- adviser), Martin Meiers (M.S., 2014, BICB), Sooraj Maharjan (M.S., 2014, BICB), David Berg (M.S., BICB, co-adviser), Deepak Sharma (M.S., 2015, BICB), Val Eisele (M.S., 2015, BICB), Steven Neier (Ph.D., 2016; co-adviser, Mayo Graduate School); Kendall Cradic (Ph.D., 2016; co- adviser, BICB) Shulan Tian (Ph.D., 2017, co-adviser, BICB) Graduate Students (current) – Postdoctoral (past) – Kevin Anderson (IMA mentor, 1997-1998), Bruce Ayati (IMA mentor, 1997-1998), Steve Krone (1994-1995, Daniel Kern (IMA mentor, 2003-2004), Paul Slade (2001-2003), Benjamin Kerr (2004-2005), Nicolas Lanchier (U. Rouen, France, 2004-2007), Alexander Young (2007-08) Postdoctoral (current) –

Undergraduate Student Mentor

Undergraduate students (past) – Sharolyn Kawakami (Spring 04-Spring 05), Mark Lubke (Spring 04- Spring 05), Grant Peterson (Spring 04-Spring 05), Ryan Peterson (Spring 04-Spring 05), Kim VanderWaal (Summer 2006).

Invited Talks

Syracuse University (March, 1989). Influence of Small Migration on the Stochastic Ising Model and the Schlogl Model. University of Southern California (Jan, 1990). Ergodic Theorems for the Multitype Contact Process. University of California, Los Angeles (Jan, 1990). Ergodic Theorems for the Multitype Contact Process. Duke University (Jan, 1990). Ergodic Theorems for the Multitype Contact Process. University of Rochester (Feb, 1990). Ergodic Theorems for the Multitype Contact Process. University of Wisconsin, Madison (Apr, 1990). Ergodic Theorems for the Multitype Contact Process. University of California, Los Angeles (Oct, 1990). Schlogl Models with Large Migration. University of California, Santa Barbara (Oct, 1990). Schlogl Models with Large Migration. AMS meeting at Irvine (Nov, 1990). Epidemics in d=2. University of California, San Diego (Jan, 1991). The Long Range Sexual Reproduction Process. University of Wisconsin, Madison (May, 1991). Schlogl Models with Large Migration. Conference on Particle Systems, Cornell/MSI (July, 1991). The Long Range Sexual Reproduction Process. IMS Annual Meeting, Atlanta GA (Aug, 1991). A Competition Model of Two Species with Different Reproduction Mechanisms. AMS meeting at Santa Barbara (Nov, 1991). A Catalytic Surface Reaction Model. University of California, Los Angeles (March, 1992). A Catalytic Surface Reaction Model. University of Utah, Salt Lake City (May, 1992). The Long Range Sexual Reproduction Process. Summer Workshop, University of Wisconsin, Madison (July, 1992). Survival of One-Dimensional Cellular Automata under Random Perturbations. University of Wisconsin, Madison, Statistics Department (October, 1992). A Poisson Approximation for Sequence Comparisons with Insertions and Deletions. University of Minnesota, Minneapolis (November, 1992). Population Models with High Dispersal Rates. University of Wisconsin, Madison, Computer Science Department (November, 1992). Statistical Aspects of Sequence Matchings. 11 University of Wisconsin, Madison (December, 1992). Survival of One-Dimensional Cellular Automata under Random Perturbations. 2nd IMS International Symposium: Probability and Applications (March, 1993). Survival of One- Dimensional Cellular Automata under Random Perturbations. Workshop on Interacting Particle Systems and Percolation, The Netherlands (June, 1993). Population Models with High Dispersal Rates. ETH Zurich (July, 1993). Population Models with High Dispersal Rates. Universitat Gottingen (July, 1993). Population Models with High Dispersal Rates. Universitat Munchen (July, 1993). Population Models with High Dispersal Rates. Universitat Heidelberg (July, 1993). Population Models with High Dispersal Rates. University of Wisconsin, Madison, Department of Meat and Animal Science (Sep, 1993). Statistical Aspects of Sequence Matching. University of Wisconsin, Milwaukee (October, 1993). Colloquium. Statistical Aspects of Sequence Matching. North Central Forest Experiment Station, St. Paul MN (January, 1994). Stepping Stone Models with Extinction and Recolonization. University of Minnesota, IMA (February, 1994). Statistical Aspects of Sequence Matching. Seminar on Stochastic Processes 1994, Texas A&M (March, 1994). Coexistence for Catalytic Surface Reaction Models. Spatial Stochastic Models in Biology, Colorado Springs (May, 1994). Stepping Stone Models with Extinction and Recolonization. IMA Minisymposium on Catalytic Surfaces, IMA University of Minnesota (June, 1994). Coexistence for Catalytic Surface Reaction Models. Conference for Women in Probability, Cornell (October, 1994). Stepping Stone Models with Extinction and Recolonization. University of Minnesota, (January, 1995). The Stepping Stone Model with Extinction and Recolonization. University of Wisconsin, Madison, Industrial Organization Workshop (April, 1995). A Spatial Competition Model. 23rd Conference on Stochastic Processes and their Applications, Singapore (June, 1995). Distributional Results for Sequence Matching with Applications to DNA Sequences. University of California, Los Angeles, (June, 1995). The Stepping Stone Model with Extinction and Recolonization. University of Southern California (June, 1995). A Spatial Competition Model for Strains of Barley Yellow Dwarf Virus. 17th Midwest Probability Conference (October, 1995) A Spatial Competition Model for Strains of Barley Yellow Dwarf Virus. Courant Institute (November, 1995) The Stepping Stone Model with Extinction and Recolonization. Rutgers University, Statistics Department (November, 1995) Statistical Aspects of Sequence Matching. Rutgers University (November, 1995) The Stepping Stone Model with Extinction and Recolonization. University of Southern California (February, 1996) Ancestral Selection Graphs. University of California, Berkeley (February, 1996),Neyman Lecture. Ancestral Selection Graphs. IMS Meeting, Richmond Virginia (March, 1996), Special Invited Lecture. Ancestral Selection Graphs. Cornell University (May, 1996) Ancestral Selection Graphs. Workshop on Interacting Particle Systems and their Applications, Israel, (June 1996), Invited Lecture Coexistence in Spatial Competition Models. University of Idaho (April, 1997), Colloquium. Competition in spatially structured habitats. Workshop on Computational Biology, University of Zurich, Switzerland, (May, 1997), Invited Lecture, Genealogies for models with selection. The Third International Symposium on Probability and its Applications, Park City, Utah (July, 1997), 12 Invited Paper Session. The Lotka-Volterra model with interspecific competition. Annual Meeting of the Society of Mathematical Biology, Raleigh, North Carolina (August, 1997), Invited Lecture. The Lotka-Volterra model with interspecific competition. Workshop on Stochastics in Population Genetics and Tree Reconstruction, Frankfurt, Germany (November 1997). Frequency-Dependent Selection. University of British Columbia (May 1998), Probability Seminar. An Explicitly Spatial Version of the Lotka-Volterra Model with Interspecific Competition. University of British Columbia (May 1998), Mathematical Biology Seminar. Spatial Strategies for Interspecific Competition. Gordon Research Conference in Theoretical Biology (June 1998). Spatial Strategies for Interspecific Competition. Conference in Honor of Harry Kesten (June 1998). The Role of Explicit Space in Plant Competition Models. Institute for Theoretical Dynamics, University of California, Davis (January 1999). The Role of Explicit Space in Plant Competition Models. Mathematical Biology Seminar, University of Arizona, (March 1999). From implicit to explicit space in ecological models. Applied Mathematics Colloquium, University of Arizona, (March 1999). The Role of Explicit Space in Plant Competition Models. Colloquium (joint with Ecology and Mathematics), Cornell University (September 1999). Diversity and Stability in Plant Communities. Conservation Biology Seminar, University of Minnesota (January 2000). Diversity and Stability in Competitive Multispecies Models. Colloquium, University of Minnesota (March 2000) (Ecology, Evolution and Behavior). The Effect of Space in Competitive Interactions. Courant Institute (New York University), Mathematical Physics and Probability Seminar (March 2000). The Ancestral Selection Graph and Gene Genealogy under Frequency Dependent Selection. University of California, Davis, Department of Mathematics (June 2000). Spatial Epidemics. University of California, Davis, Section of Evolution and Ecology (June 2000).The stability-diversity hypothesis. Invited Lecture, SMB Annual Meeting, Utah (August 2000). Calculus for Biologists. University of California, Davis, Section of Evolution and Ecology (August 2000). The role of space in plant-pathogen interactions. University of Minnesota, Twin Cities, BPTI (March 2001). Does space matter? ESA Meeting, Madison, (August 2001). Effects of Local Interactions and Local Migration on Stability. University of California, Berkeley, Mathematics Colloquium (November 2001). Does Space Matter? University of California, Davis, Graduate Student Seminar (November 2001). Does Space Matter? AAAS Meeting, Boston, Symposium on Mathematical Models for Movement and Aggregation of Cells and Organisms (February 2002). The Effects of Relative Spatial Scales on the Evolution of Resistance in Host-Pathogen Systems. BioQuest Summer Workshop (June 2002). Evolution and Ecology of Perturbed Interactions - Modeling Disequilibria in Time and Space. Modeling Workshop on Ecosystem Ecology (August 2003, 2 days). Institute of Ecosystem Studies, Millbrook, NY. Nature of Life, Itasca State Park (August 2003). Life’s Complexities. LMS Durham Symposium on Mathematical Genetics (July 2004). Ecological and evolutionary consequences of large-scale perturbations. Durham, United Kingdom. University of California, Santa Cruz (February 2005) Spatial Effects of Trophic Interactions. CSTAR First Young Researchers Workshop in Mathematical Biology, (March 2005). Plenary Talk. Spatial Effects 13 of Trophic Interactions. Mathematical Biosciences Institute, Ohio State University. Iowa State University, Ames (January 2006) Effects of Symbiotic Interactions on Plant Community Structure in Spatial Habitats. Interdisciplinary Mathematical Biology Seminar. Workshop on Spatial Ecology (March 2006) Effects of Symbiotic Interactions on Plant Community Structure in Spatial Habitats. Mathematical Biosciences Institute, Ohio State University. University of Arizona (April 2006) Effects of Symbiotic Interactions on Plant Community Structure in Spatial Habitats. EEB Seminar. Workshop on Curriculum Development (April 2006). Mathematics for Biology Students. Washington State University. University of Zurich, Switzerland (May 2006). Effects of Symbiotic Interactions on Plant Community Structure in Spatial Habitats. Special Seminar. Society for Mathematical Biology (August 2006). Effects of Symbiotic Interactions on Plant Community Structure in Spatial Habitats. Invited Lecture. Society for Mathematical Biology (August 2006). Mathematics for Biology Students. Invited Lecture. Science on the Edge Seminar Series (February 2007). Understanding Ecological Communities through Spatial Models. Michigan State University. Over the Fence: Mathematicians and Biologists Talk About Bridging the Cultural Divide (June 2007). Invited Lecture. Beyond Calculus: Integrating mathematics, statistics, and computation into biology courses. Mathematical Biosciences Institute, Ohio State University. BioQUEST Workshop (June 2007). Botany and Plant Biology Joint Congress (July 2007). The NUMBERS COUNT Project. Chicago. Institute of Mathematical Statistics Annual Meeting (August 2007). Understanding Ecological Communities. Medallion Lecture. Keynote Speaker Minnesota Council of Teachers of Mathematics Fall Conference. (October 19, 2007) Math Matters. Lakeville, MN. The 94th Annual Meeting of the Association of American Colleges and Universities: Intentional Learning, Unscripted Challenges. Featured Session: Engaging Science: Bringing Creativity to the Undergraduate Curriculum. Invited Lecture. January 25, 2008. Washington, DC. Coughlin Lecture Series, North Hennepin Community College. The Complexity of Life: From Learning in Silos to Solving Complex Societal Problems. (April 2, 2008) NESCent SELCTION Working Group. May 28-30, 2008. North Carolina. Cornell Probability Summer School. Six Lectures. June 23-July 3, 2008. Cornell University, NY. MAA Mathfest. Invited Address. Ecological and Evolutionary Consequences of Species Interactions. July 31-August 2, 2008. Madison, WI. Reinvention Center National Conference, Washington, DC, November 2008: Translating Principles of Learning Into Practice: Creating an Interdisciplinary Curriculum. Saint Olaf College, Northfield, MN (December 2008). Ecological and Evolutionary Consequences of Species Interactions. Numbers Count Workshop, Agnes Scott College, Atlanta. January 9-11, 2009. Carleton College, Northfield, MN. Translating the Principles of Learning into Practice: Creating an Integrated Curriculum. (February 2009). Minnesota Science Teacher Association 2009 Spring Conference, Rochester MN, March 2009 MnSCU Quantitative Reasoning Workshop, St. Paul, MN. April 2009. Plenary Talk: Why do we use data? NIMBioS Workshop, Tennessee. May/June 2009 BioQUEST Workshop, June 2009. HHMI-BioQUEST Workshop, Beloit. August 2009 Northeast Probability Seminar, Columbia University, NY. When Genealogy Meets Ecology. Invited Talk. November 2009. Oakwood University, AL. Numbers Count Workshop, February, 2010 14 American Association for the Advancement of Science. Space and Disease. Invited Talk. February 2010 Massachusetts Bay Community College, MA. Numbers Count Workshop, March 2010. Annual Regional Pi Mu Epsilon Undergraduate Research Conference, St. John University. Consequences of Species Interactions and Ecological and Evolutionary Consequences of Species Interactions. April 2010 2010 Experimental Biology Meeting, Irvine, CA. Enlisting Calculus to Introducing Students to System Thinking in Physiology. Invited Talk. April 2010. Beyond Bio2010, Washington DC. Deepening Quantitative Preparation: Scientific Foundation of Future Physicians and NUMB5R3 COUNT! Keynote Speaker. May 2010. HHMI-BioQUEST Workshop, Beloit. Numbers Count Workshop, June 2010 International Congress of Mathematicians, Hyderabad, India. Coevolution in Space. Invited Talk. August 2010. University of Kentucky, Lexington KY. Beyond Bio2010. October 2010. University of Minnesota. Symposium on Academic Analytics. Academic Analytics. April 2011. HHMI-BioQUEST Workshop, Lynchburg VA. March 2011. HHMI-BioQUEST Workshop, Eugene OR. April 2011. IES Conference: Preparing Today’s Students for Tomorrow’s Jobs. University of Pennsylvania, Preparing Students for Careers in Health Sciences: An Innovative and Collaborative Approach. Philadelphia, PA. May 2011. BioQUEST Workshop, Beloit WI. June 2011. 8th European Conference on Mathematical and Theoretical Biology and Annual Meeting of the Society of Mathematical Biology, Krakow, Poland. Mathematics, Statistics, and Biology: An Integrative Approach. Invited Speaker, Mini-Symposium. June 2011. BioQUEST Workshop, Oakwood University, Huntsville, AL, August 2011. UBM South Regional Conference, University of Houston. What can we learn about pathogens from mathematical models? Keynote. October 2011. Scale-IT Workshop, NimBios, University of Tennessee. January 2012. Making Biomath Happen. University of Arizona. Opportunities and Pitfalls in Creating and Sustaining an Undergraduate STEM Interdisciplinary Major. Plenary Address. June 2012. University of Maryland, College Park. What if we could start from scratch: Building an interdisciplinary curriculum on a new campus. October 2012. University of Miami. What if we could start from scratch: Building an interdisciplinary curriculum on a new campus. January, 2013. 2013 AAAS Annual Meeting, Boston. Learning Mathematics and Statistics in an Integrated Curriculum to Prepare Future Health Professionals. Minisymposium: Creating Interdisciplinary Competency- based Curricula for Undergraduate Students. February 2013. University of Delaware. A statistical approach for detecting copy number variations for next generation sequencing data. April, 2013. University of Delaware. What if we could start from scratch: Building an interdisciplinary curriculum on a new campus. April, 2013. Colorado State University. A statistical approach for detecting copy number variations for next generation sequencing data. June, 2013. Colorado State University. What if we could start from scratch: Building an interdisciplinary curriculum on a new campus. June, 2013. The Ohio State University. A statistical approach for detecting copy number variations for next generation sequencing data. MBI Workshop for Young Researchers in Mathematical Biology. August 2013. Mayo Clinic, Rochester. Future of Higher Education. Mildred l. and Garnet L. Findling Visiting Professorship in the Mayo School of Health Sciences. April 2014.

15 Medical Device Conference, University of Minnesota. Big Data, Medical Devices, and Healthcare Delivery. April 2014 WICHE Conference, Albuquerque. Faculty Innovation on a New Campus. Panel. April 2014. UCLA Symposium on Teaching Math to the Life Sciences. Designing Mathematical Sciences Undergraduate Education for 21st Century Biology. May 2014. BioQUEST Workshop, University of Delaware. June 2014. SAMSI Panel Discussion on Informatics and Education. September 2014. Design of Medical Device Conference. Human-centered Bioinformatics Services. Session organizer, April 2015. Research Data Access & Preservation Summit. Building Research Data Services at Research Universities. Keynote. Minneapolis, MN, April 2015 St. Olaf Senior Mathematical Biology Symposium. The role of big and small data in the life and health sciences. April 2015. HHMI Studio. Exploring Cardiac data through Dimensionality Reduction. Chevy Chase, MD. November 2015. NSF Germination Workshop. From 0 to 2. Washington, DC. May 2016. BDC4CM Workshop. Quantitative Techniques for Analysis of Big Data. Rochester, MN. July 2015. Thomson Reuters. Searching for Answers. Eagan, MN. June 2016. BDC4CM Workshop. Quantitative Techniques for Analysis of Big Data. New York, NY. July 2016. ABRF. Informatics Core: Adding value to data produced in core facilities. Key Note—Bridging Topic. March 2017. Campus Computing Research Infrastructure (CaRC) Conference. Professionalization Workshop. Panelist. Washington, DC. March 2018.

Last updated: March 18, 2018

16