Goals For MCB 5068 1. Obtain a solid foundation of knowledge in cell biology 2. Obtain a working knowledge of available techniques. 3. Be able to critically read and evaluate the scientific literature. 4. Be able to define and investigate a biological problem. Molecular Cell Biology 5068 To Do: Visit website: www.mcb5068.wustl.edu Sign up for course. Check out Self Assessment homework under Mercer- Introduction Visit Discussion Sections: Read “Official” Instructions TA’s: 1st Session: Nana Owusu-Boaitey
[email protected] 2nd Session: Shankar Parajuli
[email protected] 3rd Session: Jeff Kremer
[email protected] What is Cell Biology? biochemistry genetics cytology physiology Molecular Cell Biology CELL BIOLOGY/MICROSCOPE Microscope first built in 1595 by Hans and Zacharias Jensen in Holland Zacharias Jensen CELL BIOLOGY/MICROSCOPE Robert Hooke accomplished in physics, astronomy, chemistry, biology, geology, and architecture. Invented universal joint, iris diaphragm, anchor escapement & balance spring, devised equation describing elasticity (“Hooke’s Law”). In 1665 publishes Micrographia CELL BIOLOGY/MICROSCOPE Robert Hooke . “I could exceedingly plainly perceive it to be all perforated and porous, much like a Honey- comb, but that the pores of it were not regular. these pores, or cells, . were indeed the first microscopical pores I ever saw, and perhaps, that were ever seen, for I had not met with any Writer or Person, that had made any mention of them before this. .” CELL BIOLOGY/MICROSCOPE Antony van Leeuwenhoek (1632-1723) CELL BIOLOGY/MICROSCOPE Antony van Leeuwenhoek (1632-1723) a tradesman of Delft, Holland, in 1673, with no formal training, makes some of the most important discoveries in biology.