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www.spectroscopyonline.com November 2006 Current Trends in Spectrometry 47 Acronyms in columnist Ken Busch once again brings readers his comprehensive list of common acronyms used in the field of mass spectrometry.

Kenneth L. Busch

cronyms used in mass spectrometry appear in ADO Average dipole orientation printed publications of researchers working in es- AE Appearance energy A tablished areas, and also are coined at and used in AEI Associated Electric Industries, a past MS meetings, presentations, and proceedings. The latter espe- manufacturer cially reflect new applications, with new audiences, each of AGC Automatic gain control which generates a unique technical jargon. Acronyms reflect AGHIS All-glass-heated-inlet system the diverse and vibrant discipline of mass spectrometry, but AMS Accelerator mass spectrometry; adolescent shorthand-speak can become common, and practitioners in mass spectrometrists one subdiscipline tend to become more isolated, even in amu atomic mass unit conversation, from their colleagues in other areas. Re- AN Auger neutralization; application note (in JASMS) searchers enjoy coining acronyms as much as the federal ANP 2-amino-5-nitropyridine (a MALDI matrix) government, and our acronym-laden language can become ANZSMS Australian and New Zealand Society for Mass intimidating. Additionally, a new acronym can rise to gen- Spectrometry eral use, or can be orphaned and its meaning lost. In this AP Appearance potential; atmospheric pressure installment, we add more acronyms to the already extensive APCI Atmospheric pressure chemical collection, culled from recent publications, proceedings, API Atmospheric-pressure ionization and web sites in the field of mass spectrometry. Inclusion of APPI Atmospheric-pressure photoionization an acronym in this list is not explicitly an endorsement for AREX Axial resonant excitation its use by the community; the nomenclators eventually ARMS Angle-resolved mass spectrometry make their judgments, but the community itself enforces a ASGDIMS Atmospheric-sampling certain discipline. Immortality in the annals of science is ionization mass spectrometry not to be gained by coining a new acronym; a truly useful ASMS American Society for Mass Spectrometry acronym quickly becomes distributed so widely that its ASTM American Society for the Testing of Materials originator is forgotten, and even commercial trademark ATT 6-Aza-2-thiothymine (a MALDI matrix) protection can be insufficient. AVS Accelerating-voltage scan; American Vacuum For some recent additions to the acronym list, a short de- Society scription is provided, along with a recent (not necessarily the first) reference. Visit the reference given for a more B Magnetic sector mass analyzer, magnetic field; complete description. Space constraints preclude extensive magnetic sector field strength or flux density discussions here — but perhaps later in a future coffee- BAMS Bioaerosol mass spectrometry table book, when mass themselves shrink to BAT Best anode temperature the same scale. Most acronyms are composed of uppercase BDE Bond dissociation energy letters, but a few traditionally are given as sequences of low- B/E Linked scan for product ions in MS-MS ercase letters, or a mixture, and sometimes including punc- B2E Linked scan for parent ions in MS-MS tuation, all to the consternation of spell-checkers, editors, BEoQ A reverse-geometry sector instrument followed by and indexers everywhere. We retain acronyms in this list an octupole collision cell followed by a quadrupole but not specialized nomenclature or abbreviations. If your mass filter favorite acronym is missing, if you would like to argue for BEqQ A reverse-geometry sector instrument followed by an acronym’s deletion, or to correct an error, please contact a collision quadrupole followed by a quadrupole the author at [email protected]. mass filter BEMS Biomedical and Environmental Mass A Anion Spectrometry (a former MS journal) AA Amino acid BET Best emitter temperature ACMS Asilomar Conference on Mass Spectrometry BIAMS Biomolecular interaction analysis mass ADC Analog-to-digital converter spectrometry

48 Current Trends in Mass Spectrometry November 2006 www.spectroscopyonline.com

BIRD Blackbody infrared radiative CEC Consolidated Electric DCT Double charge transfer dissociation Corporation (a former MS DCTB trans-2-[3-{4-tert- BMS Biomedical Mass manufacturer) Butylphenyl}-2-methyl-2- Spectrometry; Biological Mass CEMA Channel -multiplier propenylidene] malononitrile Spectrometry array (a MALDI matrix) BMSS British Mass Spectrometry cf ConFlat DE Delayed extraction Society CFFAB Continuous-flow fast atom DEI Desorption (or direct) BNG Bradbury–Nelson gate bombardment BrMASS Brazilian Mass Spectrometry CFP Continuous flow probe DESI Desorption electrospray Society CHCA Cyano-4-hydroxycinnamic ionization BSMS Belgian Society for Mass acid (a MALDI matrix) DF Double focusing Spectrometry CI DFTPP Decafluorotriphenylphos- BTEX Benzene, toluene, CID Collision-induced phine ethylbenzene, and xylene dissociation DHB 2,5-Dihydroxybenzoic acid CIDI Collisionally induced (a MALDI matrix) c “Conventional” collision cell dissociative ionization DI Desorption ionization C Cation; coulomb; short CIT Cylindrical DIADS Delimited ion abundance communication in JASMS CM Center-of-mass database search CA Collisional activation CMD Carbohydrate membrane DIN Direct injection nebulizer CAD Collisionally activated desalter DIOSMS Desorption ionization on decomposition CNL Constant neutral loss silicon mass spectrometry CAF Chemically assisted CODA Component detection DIP Direct-insertion probe fragmentation algorithm DLI Direct liquid introduction CCA ␣-Cyano-4-hydroxycinnamic COM Center-of-mass DLV Direct laser vaporization acid (a MALDI matrix) COMSPARI Comparison of spectral DMS Differential mobility CCE-ES Controlled-current electro- retention information spectrometry chemistry electrospray CREMS Charge-reduction DNFW from the Latin for “Please do electrospray mass not mess with the The process spectrometry instrument” is, at its core, an electrochemical CRM Charged residue model; DP Direct probe; declustering process. As such, the insights and certified reference material potential; diffusion pump strategies developed over years of clas- CS Charge stripping DPBD Diphenyl butadiene sical analytical electrochemistry can be CSMS Canadian Society for Mass (a MALDI matrix) brought to bear to generate additional Spectrometry DS Data system sensitivity and specificity from the CV Compensation voltage; cone DTIMS Drift-tube ion mobility electrospray ionization. Many research voltage spectrometry workers are advancing this field. In CX Charge exchange this paper, oxidations and reductions CXP Collision-cell exit potential E Energy; electric sector of electrochemically active com- CZE–MS Capillary zone EA Electron affinity pounds are reflected in the positive electrophoresis mass EAD Electron avalanche and negative ion electrospray mass spectrometry desorption spectra. Because the current demands ECD Electron-capture dissociation on the electrochemical system are D Disproportionation factor; ECID Electron-capture–induced small, relatively simple, battery-oper- deuterium dissociation ated circuitry is devised to operate in Da Dalton ECMS Electron-capture mass conjunction with the electrospray DA Dopant-assisted spectrometry source. See V. Kertesz and G.J. Van DAC Digital-to-analog converter ECNCI Electron-capture negative Berkel, J. Amer. Soc. Mass Spectrom. DADI Direct analysis of daughter chemical ionization 17(7), 953–961 (2006). ions ECNI Electron-capture negative DAPCI Desorption atmospheric- ionization CDEM Continuous- electron pressure chemical ionization multiplier DAR Data-acquisition routine A moderator gas used in a chemical CDNT Conformation-dependent DART Direct analysis in real time ionization source decreases the energy neutralization theory DB Database of emitted from a filament to CE Charge exchange; collision dbe Double-bond equivalent energies sufficiently low that the elec- energy; capillary DCI Desorption (or direct) trons are captured by electrophilic electrophoresis chemical ionization compounds to form stable molecular

www.spectroscopyonline.com November 2006 Current Trends in Mass Spectrometry 49 negative ions M-.. The electron-capture Polyanions formed from DNA were FAB Fast-atom bombardment cross section can be increased with use stored in a QIT and irradiated with FAIMS High-field asymmetric of a proper electrophilic derivative. In laser light. The irradiation caused elec- waveform ion mobility this work, a pentafluorobenzoyl ester tron loss from the polyanion to form a spectrometry derivative is prepared of triclosan, a radical anion, and subsequent CID of FAME Fatty acid methyl ester common antibacterial agent in con- the anion provided a MS-MS spec- FC sumer products. An analytical protocol trum that provided good sequence in- FD for determination of this agent in formation and a lack of internal cleav- FFID Fission-fragment-induced and milk samples is developed ages. Preliminary work indicates that desorption and validated. See M. Allmyr, M.S. even noncovalent bonds of the DNA FFR Field-free region McLachlan, G. Sandborgh-Englund, can be preserved through the initial FI Field ionization and M. Adolfsson-Erici, Anal. Chem. electron photodetachment process. FIA Flow-injection analysis 78(18), 6542–6546 (2006). See V. Gabellica, T. Tabarin, R. An- FIB Fast-ion bombardment toine, F. Rosu, I. Compagnon, M. FID Free-induction decay ECP Emitter-current programmer Broyer, E. De Pauw, and P. Dugourd, FIK Field ionization kinetics EDD Energy-distribution Anal. Chem. 78, 6564–6572 (2006). FIMS Field-ionization mass difference spectrometry EE Even-electron ion FNB Fast-neutral beam EED Electron excitation FRET Fluorescence resonance dissociation energy transfer EHI Electrohydrodynamic FTICR Fourier-transform ion ionization cyclotron resonance EI Electron ionization; electron FTMS Fourier-transform mass impact spectrometry EIEIO Electron-induced excitation FT–TOF Fourier-transform time-of- of ions from organics flight mass spectrometry EIS External FWHH Full width at half height EJMS European Journal of Mass FWHM Full width at half maximum Spectrometry EM G Multiplier gain; glycerol EM-MS Electron monochromator (an LSIMS matrix) mass spectrometry GC Gas chromatography GC–MS Gas chromatography–mass An electron monochromator pro- spectrometry duces a well-defined source of elec- GDMS Glow discharge mass trons that can be used as part of an spectrometry electron ionization source to create ERMS Energy-resolved mass GEMIOSGas and electromagnetic ion both positive and negative ions. Stable spectrometry optical simulator molecular negative ions are formed ES Electrospray; electrospray GEMMAGas-phase electrophoretic only for electrophilic compounds in ionization mobilty molecular analysis the presence of low energy electrons, ESA Electrostatic analyzer GIANT Gas-phase ion and neutral which can be produced by the electron ESCI Combined electrospray and thermochemistry (a monochromator. In this study, the au- atmospheric pressure published compilation of thors use EM-MS to quantify three ionization source such data) different dinitroaniline pesticides ESI Electrospray ionization GLP Good laboratory practice present in tobacco smoke. The pesti- ESMS European Society for Mass GPC Gel permeation cide residues derive from the farming Spectrometry chromatography practices used to produce the various ESP Electrospray ionization tobacco products. See A.J. Dane, C.J. ESPI Electrospray ionization HABA 2-(4-Hydroxyphenylazo) Havey, and K. Voorhees, Anal. Chem. esu Electrostatic unit benzoic acid (a MALDI 78, 3227–3233 (2006). ET Electron transfer matrix) ETD Electron-transfer dissociation HASTE High-amplitude short-time EMP Electron multiplier ETV Electrothermal vaporization excitation EOID Electro-optical ion detector eV Electron volt 4-HBSA 4-Hydroxybenzenesulfonic EP Entrance potential acid (an LSIMS matrix) EPD Electron photodetachment FA Flowing afterglow; ferulic HCCA ␣-Cyano-4-hydroxycinnamic dissociation acid (a MALDI matrix) acid (a MALDI matrix)

50 Current Trends in Mass Spectrometry November 2006 www.spectroscopyonline.com

HCD Heated capillary dissociation IELC Ion-exchange liquid IP Ionization potential HCP Hollow plume chromatography IPD Ion-photon detector H/D Hydrogen–deuterium IJMSIP International Journal of Mass IRMPD Infrared multiphoton HDX Hydrogen–deuterium Spectrometry and Ion Physics dissociation exchange (volumes 1–62) IRMS Isotope ratio mass HE High energy International Journal of Mass spectrometry HECD Hot electron capture Spectrometry and Ion ISD In-source decay dissociation Processes (after volume 62) ISMAS Indian Society for Mass 2-HEDS 2-Hydroxyethyl disulfide IJMS International Journal of Mass Spectrometry (an LSIMS matrix) Spectrometry ISP Ionspray HILIC Hydrophilic interaction IKE(S) Ion kinetic energy ISR Ion–surface reaction liquid chromatography (spectrometry) ITD Ion-trap detector HKSMS Hong Kong Society for Mass IMAC Immobilized metal affinity ITMS Ion-trap mass spectrometry Spectrometry chromatography ITPMS Isotacophoresis mass HMM High molecular mass IMS Ion mobility spectrometry; spectrometry HPA 3-Hydroxypicolinic acid imaging mass spectrometry IUPAC International Union of Pure (a MALDI matrix) and Applied Chemistry 2-HPEA 2-Hydroxyphenethyl alcohol Imaging mass spectrometry based (an LSIMS matrix) on MALDI uses mass spectra convo- JASMS Journal of the American HPMS High-pressure mass luted with planar (x,y) coordinates to Society for Mass Spectrometry provide spatial tracking of both en- JEOL Japan Electro-Optics HRMS High-resolution mass dogenous and exogenous compounds Laboratory spectrometry with spatial resolution and molecular JMS Journal of Mass Spectrometry HSI Hyperthermal surface specificity. In this work, the authors ionization track drug and drug metabolite distri- K Kelvin HSMS Headspace mass butions within whole-body tissue sec- KCMS Knudsen cell mass spectrometry tions. When the tissue sections are spectrometry HT Hadamard transform; high sampled in time, the temporal distri- kDa Kilodalton tension, which is a Britishism butions also can be established. This KERD Kinetic energy release for HV (high voltage) work is one example of a rapidly grow- distribution HTMS High temperature mass ing area of application. See S. Khatib- K+IDS Potassium ion desorption spectrometry Shahidi, M. Andersson, J.L. Herman, spectrometry HT-TOFMS Hadamard transform T.A. Gillespie, and R.M. Caprioli, Anal. KM Kinetic method time-of-flight mass Chem. 78, 6448–6456 (2006). KNN K-nearest neighbor spectrometry HV High voltage IMSS International Mass L Length (of flight tube) HXMS Hydrogen–deuterium Spectrometry Society; Irish LA Laser ablation exchange mass spectrometry Mass Spectrometry Society INC Ion-neutral complex While MALDI is used for biological IAA Indole acrylic acid (a MALDI matrix) IC Ion chromatography ICAT Isotope-coded affinity tag ICDR Ion cyclotron double resonance ICEMS Ion-pair liquid chromatography electrospray ionization mass spectrometry IC–MS Ion chromatography–mass spectrometry ICP–MS Inductively coupled plasma– mass spectrometry ICR Ion cyclotron resonance IDMS Isotope dilution mass spectrometry IE Ionization energy; ionizing energy; ion evaporation

www.spectroscopyonline.com November 2006 Current Trends in Mass Spectrometry 51 analyses, the direct impact of a laser on a surface such as a silicate glass produces a vaporized aerosol that can then be directed into an ICP-MS sys- tem for elemental analysis. For the ICP-MS system to provide an accurate analysis, the vaporization and transfer efficiency must be mass- and element- independent. This ideal case is not achieved in practice, and the authors of this careful work on laser ablation study two different laser ablation sys- tems, and different carrier gases, as means of sample introduction in ICP- MS. See Z. Wang, B. Hattendorf, and D. Gunther, J. Amer. Soc. Mass Spec- trom. 17(5), 641–651 (2006).

LAMMA Laser microprobe mass chromatography few micrometers were shown to pro- analyzer MALD Matrix-assisted laser vide superior mass spectra. See I. LAMPASLaser mass analyzer for desorption Feuerstein, M. Najam-ul-Huq, M. particles in the airborne state MALDI Matrix-assisted laser Rainer, L. Trojer, R. Bakry, N.H. LBO Light beam oscillograph desorption ionization Aprilita, G. Stecher, C. Huck, H. LC-MS Liquid chromatography– MAPS Method for analyzing Klocker, G. Bartsch, A. Guttman, and mass spectrometry patterns in spectra G.K. Bonn, J. Amer. Soc. Mass Spec- LD Laser desorption MB Molecular beam trom. 17(9), 1203–1208 (2006). LDI Laser desorption ionization MBMS Molecular beam mass LDLP Laser desorption–laser spectrometry MESIMSMatrix-enhanced secondary photoionization MCA Multichannel analyzer ion mass spectrometry LE Low energy MCI Massive cluster impact MI Metastable ion LI Liquid ionization MCMS Midwest Center for Mass MID Multiple ion detection LIAD Laser-induced acoustic Spectrometry MIKE(S) Mass-analyzed ion kinetic desorption MCP Microchannel plate energy (spectrometry) LIMA Laser ionization mass (detector) MIM Multiple ion monitoring analyzer; laser ion MCPD Microchannel plate detector microprobe analyzer MEND Matched filtration with A lowered limit of detection can be LIT experimental noise achieved in mass spectrometric analyses LMCO Low mass cut-off determination with the use of selected ion monitoring; LMM Low molecular mass MDMS Microdialysis mass monitoring the intensities of several LMMS Laser microprobe mass spectrometry ions in time (for instance, as mixture spectrometer MDL Method detection limit components are eluted from a gas chro- LMS Laser mass spectrometry MELDI Material-enhanced laser matograph) is called multiple ion mon- LMW Low molecular weight desorption–ionization itoring. Early work suggested that mon- LOD Limit of detection itoring ions of three different selected LOQ Limit of quantification The authors describe various func- masses should be sufficient to confirm LRB Laboratory reagent blank tionalized carrier materials (listing cel- the presence of a targeted compound. LSIMS Liquid matrix secondary ion lulose, silica, a glycidyl methacrylate– However, using an expanded library of mass spectrometry divinylbenzene polymer, and diamond 100,000 electron ionization mass spec- LTOF Laser time-of-flight; linear powder) that act as matrices for a rela- tra, and more generalized restraints on time-of-flight tively conventional MALDI-TOF the relative intensities of ions in the LV/EI Low voltage electron analysis. The advantages of MELDI in- standard mass spectra of the targeted ionization clude the high capacity and selective compound, recent work suggests that functionality useful in binding serum additional ions may need to be moni- m Mass of the ion in units of u constituents to be analyzed. The spec- tored and the potential for false posi- M/A Matrix/analyte ratio tral effects of particle shape and pore tives reassessed. See S.E. Stein and D.N. MAGIC Monodisperse aerosol size were delineated; highly porous Heller, J. Amer. Soc. Mass Spectrom. generator interface to spherical particles with diameters of a 17(6), 823–835 (2006).

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observed in this work, and the results Biotechnology Information MIMS Membrane introduction that showed an enhancement in matrix NCE Normalized collision energy mass spectrometry suppression effect with thinner layers NCI Negative ion chemical MIP Microwave-induced plasma considered in terms of a model that ionization MNBA m-Nitrobenzyl alcohol, an considers a first-step ionization of the NET Normalized elution time LSIMS matrix matrix, enhanced in the near vicinity of NI Negative ion MNDO Modified neglect of the metal surface. See G. McCombie NICI Negative ion chemical differential overlap and R. Knochenmuss, J. Amer. Soc. Mass ionization MO Molecular orbital Spectrom. 17(5), 737–745 (2006). NOBA m-Nitrobenzyl alcohol MOWSE Molecular weight search (an LSIMS matrix) MPD Multiphoton dissociation MSM Multiple scattering method +NR+ Neutralization reionization; MPI Multiphoton ionization MSR Mass Spectrometry Reviews a positive ion is neutralized MPM Multiple peak monitoring MS-MS Mass spectrometry-mass and then reionized MQDT Multichannel quantum spectrometry NRMS Neutralization reionization defect theory MSSJ The Mass Spectrometry mass spectrometry MRM Multiple reaction monitoring Society of Japan NSI Nanospray ionization MSn If n = 2, MS-MS. If n = 3, MSSS Mass spectral search system NSMS Norwegian Society for Mass MS-MS-MS. Repeat as Spectrometry necessary. The first mass spectral database used NVMS Dutch Society for Mass MSB Mass Spectrometry Bulletin for organic compound identification Spectrometry MSD Mass-selective detector was developed at NIH and used a sys- MSDC Mass Spectrometry Data tem called the MSSS. It was imple- o Orthogonal Center mented on a PDP-10 computer and oa Orthogonal acceleration MSE Matrix suppression effect was first described in the journal Ana- ODN Oligodeoxynucleotide lytical Chemistry in 1972. The first dial- OE Odd-electron ion An electrospray sample deposition up connection to the mainframe com- OMS Organic Mass Spectrometry technique was used to deposit puter used a 110-baud modem. Feeling oTOF Orthogonal (source) time-of- matrix–analyte solutions of varying old yet? See S.R. Heller, Today’s Chemist flight thickness onto a surface then analyzed at Work 8(2), 45–46, 49–50 (1999). by MALDI mass spectrometry. A matrix PA Proton affinity suppression effect score was calculated MULTUM Multiturn mass PAD Postacceleration detector by dividing a standard analyte ion re- spectrometer PAI Postablation ionization sponse by the sum of the analyte and MW Molecular weight PALMS Particle analysis by laser mass matrix ion responses for the samples of Mwt Molecular weight spectrometry varying thickness. The matrix suppres- PBM Probability-based matching sion is therefore a measure of how the N Neutral molecule or species PBMS Particle-beam mass matrix signal could be reduced relative NBA m-Nitrobenzyl alcohol spectrometry to a persistent analyte ion signal. The (an LSIMS matrix) PCA Principal component analysis well-known “first shot” effect could be NCBI National Center for PCI Positive ion chemical ionization P2CID Parallel collision-induced dissociation

A quadrupole-time-of-flight mass spectrometer is used to generate MS- MS spectra with higher signals than a single collision-induced dissociation (CID) process. A higher cone voltage is used to effect source CID, and then these energized ions are passed into a collision cell, where a second CID process ensues. The authors claim a two- to fourfold increase in the prod- uct ion intensities observed for higher mass ions, which increases, for exam- ple, the intensities of structurally in- formative sequence ions from pep-

www.spectroscopyonline.com November 2006 Current Trends in Mass Spectrometry 53

REMPI Resonance-enhanced multiphoton ionization rf Radio frequency; Response factors RGA Residual gas analyzer RI Relative intensity RIMS Resonance-ionization mass spectrometry RiT Rectilinear ion trap RLCT Rayleigh limiting charge theory RN Resonance neutralization ROOMS Regular old ordinary mass spectrometry R2PI Resonant two-photon ionization RP Resolving power RPD Retarding potential difference tides. See A.A. Ramos, H. Yang, L.E. PSM Peptide-spectrum match RPLC Reversed-phase liquid Rosen, and X. Yao, Anal. Chem. PSPF Postsource pulse focusing chromatography 78(18), 6391–6397 (2006). PTM Posttranslational RRKM Rice, Ramsperger, Kassel, and modification Marcus PCR Polymerase chain reaction PTR Proton-transfer reaction RSMS Rapid single particle mass PD Plasma desorption; PTSM Polish Society for Mass spectrometer photodissociation Spectrometry rTOF Reflectron time-of-flight PDF Pulsed dynamic focusing PyMS Pyrolysis mass spectrometry PDMS Plasma desorption mass SA Sinapinic acid (a MALDI spectrometry q Quadrupole device used in matrix) PEPICO Photoelectron-photoion rf-only mode as a collision SAAMS South African Association for coincidence spectroscopy cell Mass Spectrometry PES Photoelectron spectroscopy Q Quadrupole mass filter SCMS Sanibel Conference on Mass PFK Perfluorokerosene Q Reaction endothermicity Spectrometry PFT Porous flow-through QA Quality assurance SCX Strong cation exchange (electrode) QC Quality control SDM Selected dissociation PFTBA Perfluorotributylamine qCID Collision-induced monitoring PHD Pulse height distribution dissociation accomplished SDME Single-drop microextraction PHT Peptide hits technique within an rf-only quadrupole SEAC Surface-enhanced affinity PI Positive ion QCPE Quantum Chemistry capture PID Particle-induced desorption; Program Exchange SEC Size exclusion photon-induced dissociation QET Quasi-equilibrium theory chromatography PIE Photoionization efficiency QFTMS Quadrupole Fourier- SEEM Spanish Society for Mass PIT Protein-identification transform mass spectrometry Spectrometry technology QIT SELDI Surface-enhanced laser PIT-MS Proton-transfer ion-trap QLT Quadrupole linear ion trap desorption ionization mass spectrometry QTOF Quadrupole followed by a SEND Surface-enhanced neat PIPECO Photoion-photoelectron time-of-flight mass analyzer desorption coincidence spectroscopy QUISTOR Quadrupole ion storage trap SFC-MS Supercritical fluid PLE Pressurized liquid extraction r radius of electric or magnetic chromatography–mass PMF Peptide mass fingerprinting sector spectrometry PMM Peptide mass maps RA Relative abundance; SFE Supercritical fluid extraction PMS Parallel mass spectrometry trans,trans-retinoic acid SFSM French Society for Mass PPINICI Pulsed positive-ion (a MALDI matrix) Spectrometry negative-ion chemical RCM Rapid Communications in SGMS Swiss Group for Mass ionization Mass Spectrometry Spectrometry ppm Part per million rdbe Rings plus double bonds SI Spray ionization; surface PSD Postsource decay equivalent ionization PSI Pulsed sample introduction REE Rare earth elements SID Surface-induced dissociation

54 Current Trends in Mass Spectrometry November 2006 www.spectroscopyonline.com

SIFDT Selected ion flow drift tube moment theory spectrometry; SIFT Selected ion flow tube SWIFT Stored-waveform inverse mass spectrometry SILVER Spectrum intensity likeli- Fourier transform ToF Time-of-flight hood viewer SWIM Stored waveform ion TOF Time-of-flight SIM Selected-ion monitoring modulation TOFMS Time-of-flight mass SIMBROC Simulated background and spectrometry reduction/oxidation t Ion flight time; time TQ Triple quadrupole calculations T Tesla TQMS Triple-quadrupole mass SIMS Secondary ion mass TAC Time-to-amplitude con- spectrometry spectrometry verter TRPD Time-resolved SIN Surface-induced TAMS Tandem accelerator mass photodissociation neutralization spectrometry TS Transition state; transition SIOMS Surface ionization organic TDC Time-to-digital converter structure mass spectrometry TDMS Thermal desorption mass TSP Thermospray SIR Selected-ion recording spectrometry TSQ Triple-stage quadrupole SIRMS Stable-isotope-ratio mass TEL Translational energy loss spectrometry TEPSICOThreshold electron photoion u Mass unit (1/12 of the mass SMB Supersonic molecular beam secondary ion coincidence of 12C), now replaced by SMOKE Stored modulation of kinetic TES Translational energy dalton energy spectroscopy UVLD Ultraviolet laser desorption SMOW Standard mean ocean water TGAMS Thermogravimetric analysis UVPD Ultraviolet photodissocia- SMSS Swedish Society for Mass mass spectrometry tion Spectrometry TG GC-MS Thermogravimetry gas S/N Signal-to-noise ratio chromatography–mass v Ion velocity SOMO Singly occupied molecular spectrometry V Accelerating voltage orbital THAP 2,4,6-Trihydroxyacetophe- VG Vacuum Generators, former SPE Solid-phase extraction none (a MALDI matrix) name of a manufacturer of SPME Solid-phase microextraction TI mass spectrometers SRBC Simulated reduction and TIC Total ion current VOC Volatile organic compound background calculations TID Trapped-ion detector; VMSOW Vienna mean standard ocean SRM Selected reaction monitor- thermally induced water ing; standard reference ma- dissociation VTST Variational transition state terial TIMS Thermal-ionization mass theory SSIMS Static secondary-ion mass spectrometry spectrometry TISI Turbo ionspray ionization W SSMS Spark source mass TIP True isotopic pattern spectrometry TLC-MS Thin layer z Charge state of the ion in STIRS Self-training interpretive chromatography–mass units of the electric charge and retrieval system spectrometry ZPE Zero-point vibrational STMT Stieltjes–Tchebycheff TMS Trimethylsilyl; tandem mass energy

Kenneth L. Busch (KLB) has taught the course: “Introduction to Mass Spectrometry” for the past 15 years at pro- fessional conferences. During those 15 years, mass spectrometry has been reinvented, reconfigured, redirected, and submerged in acronyms. Slang and jargon in mass spec- trometry is a separate issue that will be tackled ASAP. The contents of this article represent the views of the author (MHOs), and not those of the National Science Foundation (NSF). KLB can be reached at [email protected].