A Pooled Analysis of More Than 1 Million Participants
Original Investigation | Global Health Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia A Pooled Analysis of More Than 1 Million Participants Jae Jeong Yang, PhD; Danxia Yu, PhD; Wanqing Wen, MD; Eiko Saito, PhD; Shafiur Rahman, MSc; Xiao-Ou Shu, PhD; Yu Chen, PhD; Prakash C. Gupta, PhD; Dongfeng Gu, PhD; Shoichiro Tsugane, PhD; Yong-Bing Xiang, MD; Yu-Tang Gao, MD; Jian-Min Yuan, PhD; Akiko Tamakoshi, PhD; Fujiko Irie, PhD; Atsuko Sadakane, PhD; Yasutake Tomata, PhD; Seiki Kanemura, PhD; Ichiro Tsuji, PhD; Keitaro Matsuo, PhD; Chisato Nagata, PhD; Chien-Jen Chen, ScD; Woon-Puay Koh, PhD; Myung-Hee Shin, PhD; Sue K. Park, PhD; Pei-Ei Wu, PhD; You-Lin Qiao, PhD; Mangesh S. Pednekar, PhD; Jiang He, PhD; Norie Sawada, PhD; Hong-Lan Li, MD; Jing Gao, MD; Hui Cai, PhD; Renwei Wang, MD; Toshimi Sairenchi, PhD; Eric Grant, PhD; Yumi Sugawara, PhD; Shu Zhang, PhD; Hidemi Ito, PhD; Keiko Wada, PhD; Chen- Yang Shen, PhD; Wen-Harn Pan, PhD; Yoon-Ok Ahn, PhD; San-Lin You, PhD; Jin-Hu Fan, PhD; Keun-Young Yoo, PhD; Habibul Ashan, MD; Kee Seng Chia, MD; Paolo Boffetta, MD; Manami Inoue, MD; Daehee Kang, PhD; John D. Potter, PhD; Wei Zheng, PhD Abstract Key Points Question What is the association IMPORTANCE Asia is home to the largest diabetic populations in the world. However, limited between diabetes and mortality in Asian studies have quantified the association of diabetes with all-cause and cause-specific mortality in populations? Asian populations. Findings In this pooled analysis of data OBJECTIVES To evaluate the association of diabetes with all-cause and cause-specific mortality in from more than 1 million individual Asia and to investigate potential effect modifications of the diabetes-mortality associations by participants of 22 studies in Asia, participants’ age, sex, education level, body mass index, and smoking status.
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