Annual TERMIS – EU Meeting
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TERMIS-EU 2006 Tissue Engineering and Regenerative Medicine International Society Congress venue De Doelen Rotterdam The Netherlands Congress Secretariat Erasmus MC - Het Congresbureau P.O. Box 2040 3000 CA Rotterdam The Netherlands phone: +31 10 408 78 78 www.hetcongresbureau.nl © 2006 The Congress Secretariat Erasmus MC The Congress Secretariat P.O. Box 2040 3000 CA Rotterdam The Netherlands Lay-out: OMK & N.J. Koc No part of this publication may be translated or reproduced, in any form or by any means, without written permission from Erasmus MC, Het Congresbureau, Rotterdam, The Netherlands. 2 Table of Content Presidential address & Welcome 5 General information 7 Scientific Program 9 TERMIS-EU Meeting at a glance 11 Poster overview 21 Abstracts 27 Posters 159 Sponsors 235 First Author’s index 244 Keyword index 247 3 4 Presidential Address Last year, based on the strong need for a worldwide coordination between all tissue engineers and between all tissue engineering societies, the European Tissue Engineering Society (ETES), Tissue Engineering Society International (TESI) and several Asian societies joined together to form the Tissue Engineering and Regenerative Medicine International Society (TERMIS). The creation of TERMIS has already resulted in a coordinated sequence of annual meetings in the field and is supporting the challenging development of a worldwide registry of clinical trials for tissue engineering products and processes. In order to maintain the possibility to organize initiatives reflecting the geographical/cultural needs and exploiting local resources, TERMIS is structured in continental chapters, including the European section (TERMIS-EU). I’m happy to welcome you to the first annual meeting of TERMIS-EU! By participating to this meeting, you have had the possibility to get/renew your membership to TERMIS, which among other benefits offers complimentary personal on-line access rights to Tissue Engineering, the official journal of the society. Most importantly, your presence in Rotterdam contributes to making the TERMIS-EU meeting as the main annual event in the field, bringing together the broad European tissue engineering community and promoting its development, consolidation and international networking. I wish you a stimulating, fruitful and enjoyable meeting! Sincerely, Ivan Martin, TERMIS-EU Chair Welcome Dear Colleagues, I am pleased to welcome you to Rotterdam for the annual meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society, also on behalve of the rest of the local organizing committee. We would like to thank all the presenters for submitting their work thereby enabling us to put together an interesting programme with over 200 oral presentations and almost 150 posters. We are confident that in the venue of De Doelen, you will be able to present and discuss your work in a pleasant environment. We would like to thank the sponsors for making this meeting possible, the reviewers for their help with selecting the abstracts and the many others who helped with various aspects like putting together the program, organizing all kind of logistical issues, giving tips and ideas or promoting the meeting. I would like to draw your attention especially to the many activities that will be organized by the Student and Young Investigator Section (SYIS). This is new in the European meeting and I hope it will stimulate the young researchers to become/stay actively involved in tissue engineering and regenerative medicine. Finally, the social aspects of the meeting are as important as the scientific aspects. Don’t forget to enjoy Rotterdam! There is a large variety of places you can go to for a drink or a bite, in the mean time discussing the latest scientific results or the meaning of life. Enjoy the meeting and enjoy Rotterdam, Gerjo van Osch , Conference Chair 5 6 General Information Congress Committee 2006 Congress Chair Gerjo J.V.M. van Osch, Ph.D. Erasmus MC - University Medical Center Rotterdam Department of Orthopaedics and Department of Otorhinolaryngology Room Ee 16.55 P.O. Box 2040 3000 CA Rotterdam The Netherlands Phone: +31 (0)10 4087661 Fax: +31 (0)10 4089415 Email: [email protected] Local organizers Gerjo van Osch Rotterdam Harrie Weinans Rotterdam Roel Kuijer Groningen Ruud Bank Leiden/Amsterdam Pieter Buma Nijmegen Hinne Rakhorst Rotterdam Regional Scientific Committee Frank Baaijens, Eindhoven Clemens van Blitterswijk, Enschede Sjoerd Bulstra, Groningen Jan de Boer, Enschede Gerard Boer, Amsterdam Rob Chamuleau, Amsterdam Wouter Dhert, Utrecht Pieter Doevendans, Utrecht Marco Harmsen, Groningen Stefan Hofer, Rotterdam Jan Feijen, Enschede Carl Figdor, Nijmegen/Enschede Hans von den Hoff, Nijmegen John Jansen, Nijmegen Jenneke Klein-Nulend, Amsterdam Peter van der Kraan, Nijmegen Toin van Kuppevelt, Nijmegen Peter Lohuis, Amsterdam Marja van Luyn, Groningen Esther Middelkoop, Beverwijk Christine Mummery, Utrecht Daniel Saris, Utrecht 7 TERMIS Board 2006 President: Alan J. Russell President-Elect: Jöns Hilborn Secretary: David S. Smith Continental Chair Europe Ivan Martin Contintental Chair Elect David Williams Member-At-Large James Kirkpatrick Continental Council Members Augustinus Bader Yann Barrandon Aldo Boccaccini Robert Brown Ranieri Cancedda Peter Frey Timothy Hardingham Ulrich Nöth Rui Reis Michael Sittinger Björn Stark Clemens van Blitterswijk Gerjo van Osch Invited Faculty Joelle Amedee, Inserm U-Universite Victor Segalen Bordeaux Cedex, (France) Charles Archer, Cardiff University, Cardiff, (United Kingdom) Frank Baayens, Technical University, Eindhoven, (The Netherlands) Dan Bader, Queen Mary University of London, (United Kingdom) Ruud Bank, TNO Leiden & Free University Amsterdam, (The Netherlands) Frank Barry, National Centre for Biomedical Engineering Science, Galway, (Ireland) Clemens van Blitterswijk, Technical University Twente, Enschede, (The Netherlands) Joost de Bruijn, Queen Mary University of London, UK & Progentix BV, (The Netherlands) Joseph Frank, National Institute of Health, Bethesda, (USA) C James Kirkpatrick, Johannes Gutenberg University, Mainz, (Germany) Themis Kyriakides, Yale University, New Haven, (USA) Frank Luyten, University of Leuven, Leuven, (Belgium) David Mooney, Harvard University, Boston, (USA) Christine Mummery, Hubrecht Laboratory, Utrecht, (The Netherlands) Steve White, University of Glasgow, Glasgow, (United Kingdom) 8 Scientific Program 9 10 11 12 13 14 15 16 17 18 19 20 Poster overview P1 Influence of nano-vibration stimuli on cell differentiation for tissue engineering Kimura et al, TOKYO, Japan P2 Three-dimensional cell seeding and growth in radial-flow perfusion bioreactor Yamaoka et al, SUITA, Japan P3 Novel perfusion bioreactor system increased the thickness of three-dimensional myocardial tissues bioengineered by cell sheet technology Sawada et al, TOKYO, Japan P4 The influence of compressive loading on calcium distribution in skeletal muscle cells Langelaan et al, EINDHOVEN, The Netherlands P5 Automation of the liquid handling cell culture processes of a 3D in vitro engineered tissue model for rheumatoid arthritis using the CyBi®-Disk Workstation Ibold, et al, BERLIN, Germany P6 A study on nutrient mass transport through porous channeled flat sheet membrane and prediction of maximum scaffold thickness for viable cell culture (In-vitro) by modelling Bettahalli et al, ENSCHEDE, The Netherlands P7 Requirements of Specialised Bioreactor for Engineering and Characterisation of Extracellular Matrix (ECM) Sebastine et al, LOUGHBOROUGH, United Kingdom P8 A novel, versatile, GLP-compatible bioreactor for electromechanical conditioning of engineered tissues Sadr et al, MILANO, Italy P9 Multiscale modelling of nutrient transport in bioreactor for growing 3D bone tissues: sub-cellular to laboratory scale Das et al, OXFORD, United Kingdom P10 BioDynamic Test Instrument for the Characterization of Tissues and Biomaterials Williams et al, EDEN PRAIRIE, USA P11 Coupling Mechanic, Transport and Biosynthetic Activity in Cartilage Constructs Urciuolo et al, NAPOLI, Italy P12 Computational Multi-Scale Approach of Bone Growth in Scaffolds Sanz et al, ZARAGOZA, Spain P13 A Bioreactor for Mechano-Stimulation and Mechanical Property Evaluation in Functional Tissue Engineering Bottlang, et al, PORTLAND, United States of America P14 Effect of mechanical stimulation on the redifferentiation of dedifferentiated chondrocytes in alginate bead culture Wang, MS. et al, France P15 Electrospun Starch-polycaprolactone Nano Fibrous Scaffold Ylikauppila et al, TAMPERE, Finland P16 Mechanical straining of adipose tissue derived mesenchymal stem cells for application in bone tissue engineering Diederichs et al, HANNOVER, Germany P17 Porous Hydroxyapatite Ceramics with High Mechanical Strength Made from Bovine-Bioglass Composite Punyanitya et al, CHIANGMAI, Thailand P18 Comparison of a Tissue-engineered bone and a Bovine-derived xenograft on Maxillary sinus augmentation in Rabbits Song et al, SEOUL, South-Korea P19 Growth of the skeletal bones after implantation of biogenic hydroxyapatite (HA) into metadiahpysis of the tibia Luzin et al, LUHANSK, Ukraine P20 Bone substitutes from alveolar bone cells obtained from dental implant preparation sites Malicev et al, LJUBLJANA, Slovenia P21 Application of a new rotating bed bioreactor system for cultivating 3D bone constructs Kasper et al, HANNOVER, Germany P22 Characterization and Sintering of Bovine Hydroxyapatite Nanoparticles Ruksudjarit et al, CHIANGMAI, Thailand P23 Characterization