DOCSLIB.ORG

Amitriptyline 10Mg, 25Mg and 50Mg Tablets

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Amitriptyline 10Mg, 25Mg and 50Mg Tablets Side effects listed below have been reported in the following • hepatitis (inflammation of the liver) with signs such as dark frequencies: urine, weight loss and jaundice Very common (may affect more than 1 in 10 people): • hot flush • sleepiness/drowsiness • dry eyes Package leaflet: Information for the patient • shakiness of hands or other body parts • stomach pain, sore mouth • dizziness, headache, dizziness when you stand up due to • itching. Amitriptyline 10mg, 25mg low blood pressure (orthostatic hypotension) An increased risk of bone fractures has been observed in • irregular, hard, or rapid heartbeat patients taking this type of medicine. and 50mg tablets • dry mouth, constipation, nausea When used for the treatment of bed wetting in children, the • excessive sweating side effects are less frequent. The most common side effects Read all of this leaflet carefully before you start Warnings and precautions • weight gain are drowsiness, blurred vision, dilated pupils, constipation, Talk to your doctor or pharmacist before taking • slurred or slow speech taking this medicine because it contains important sweating, itching and dry mouth. Changes in behaviour have information for you. Amitriptyline tablets. • aggression also occurred in children receiving amitriptyline. • congested nose. • Keep this leaflet. You may need to read it again. Heart rhythm disorders and hypotension may occur if Reporting of side effects • If you have any further questions, ask your doctor or you receive a high dosage of amitriptyline. This might Common: (may affect up to 1 in 10 people): If you get any side effects, talk to your doctor, pharmacist or also occur in usual doses if you have pre-existing heart • confusion nurse. This includes any possible side effects not listed in this pharmacist. disease. • sexual disturbances (decreased sex-drive, problems with leaflet. You can also report side effects directly via the Yellow • This medicine has been prescribed for you only. Do not erection) The use of Buprenorphine together with Amitriptyline Card Scheme at www.mhra.gov.uk/yellowcard or search for pass it on to others. It may harm them, even if their tablets can lead to serotonin syndrome, a potentially • disturbance in attention MHRA Yellow Card in the Google Play or Apple App Store. signs of illness are the same as yours. • changes in taste life threatening condition (see ‘Other medicines and Amitriptyline tablets’). • numbness or tingling in the arms or legs By reporting side effects, you can help provide more • If you get any side effects, talk to your doctor or • disturbed coordination information on the safety of this medicine pharmacist. This includes any possible side effects not Prolonged QT interval • dilated pupils listed in this leaflet. See section 4. A heart problem called “prolonged QT interval” (which is • heart block 5 How to store Amitriptyline tablets shown on your electrocardiogram, ECG) and heart rhythm • fatigue What is in this leaflet disorders (rapid or irregular heart beat) have been reported • low sodium concentration in the blood Keep this medicine out of the sight and reach of children. 1 What Amitriptyline tablets are and what with Amitriptyline tablets. Tell your doctor if you: • agitation Store below 25°C in a dry place, protected from light. • have slow heart rate • urination disorders Do not use Amitriptyline tablets after the expiry date stated on they are used for • have or had a problem where your heart cannot pump the • feeling thirsty. the carton. The expiry date refers to the last day of that month. 2 What you need to know before you take blood around your body as well as it should (a condition called heart failure) Uncommon (may affect up to 1 in 100 people): Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away Amitriptyline tablets • are taking any other medication that may cause heart • excitement, anxiety, difficulties sleeping, nightmares problems • convulsions medicine you no longer use. These measures will help protect 3 How to take Amitriptyline tablets the environment. 4 • have a problem that gives you a low level of potassium or • tinnitus Possible side effects magnesium, or a high level of potassium in your blood • increased blood pressure 5 How to store Amitriptyline tablets • have a surgery planned as it might be necessary to stop • diarrhoea, vomiting 6 Contents of the pack and other 6 Contents of the pack and other the treatment with amitriptyline before you are given • skin rash, nettle rash (urticaria), swelling of the face and information anaesthetics. In the case of acute surgery, the anaesthetist tongue What Amitriptyline tablets contain information should be informed about the treatment of amitriptyline • difficulties passing urine The active substance is amitriptyline hydrochloride. • increased production of breast milk or breast milk outflow • have an over-active thyroid gland or receive thyroid Each tablet contains either 10mg, 25mg or 50mg of the active 1 What Amitriptyline tablets are and what medication. without breast feeding ingredient. • increased pressure in the eyeball they are used for The other ingredients are lactose monohydrate, Amitriptyline belongs to a group of medicines called tricyclic Thoughts of suicide and worsening of your • collapse conditions microcrystalline cellulose (E460), maize starch, colloidal antidepressant drugs. This medicine is used to treat: depression • worsening of cardiac failure anhydrous silica, magnesium stearate, hypromellose (E464), • Depression in adults (major depressive episodes) If you are depressed, you can sometimes have thoughts of • liver function impairment (e.g. cholestatic liver disease). titanium dioxide (E171), macrogol. • Neuropathic pain in adults harming or killing yourself. These may be increased when first Rare (may affect up to 1 in 1,000 people): The 10mg tablet also contains: indigo carmine (E132). • Chronic tension type headache prophylaxis in adults starting antidepressants, since these medicines all take time to • decreased appetite The 25mg tablet also contains: talc (E553b), quinoline yellow • Migraine prophylaxis in adults work, usually about two weeks but sometimes longer. • delirium (especially in elderly patients), hallucinations (E104), iron oxide (E172), sunset yellow (E110), indigo carmine • Bed-wetting at night in children aged 6 years and above, You may be more likely to think like this: • abnormality in the heart’s rhythm, or heartbeat pattern (E132). only when organic causes, such as spina bifida and related • If you have previously had thoughts about killing or harming • swelling of the salivary glands The 50mg tablet also contains: talc (E553b), quinoline yellow disorders, have been excluded and no response has been yourself. • hair loss (E104), iron oxide (E172). achieved to all other non-drug and drug treatments, • If you are a young adult. Information from clinical trials has shown an increased risk of suicidal behaviour in young • increased sensitivity to sunlight What Amitriptyline tablets look like and contents of the including muscle relaxants and desmopressin. This medicine • breast enlargement in men should only be prescribed by doctors with expertise in adults (less than 25 years old) with psychiatric conditions pack who were treated with an antidepressant. • fever Amitriptyline 10mg tablets are blue film-coated tablets. treating patients with persistent bed-wetting. • weight loss Amitriptyline 25mg tablets are yellow, circular, biconvex, film- If you have thoughts of harming or killing yourself at any time, • abnormal results of liver function tests. coated tablets impressed ‘C’ on one face and the identifying 2 What you need to know before you take contact your doctor or go to a hospital straight away. Very rare (may affect up to 1 in 10,000 people): letters ‘AB’ on the reverse. Amitriptyline tablets You may find it helpful to tell a relative or close friend that you • heart muscle disease Amitriptyline 50mg tablets are tan film-coated tablets. are depressed, and ask them to read this leaflet. You might Do not take Amitriptyline tablets if you or your child (if they • feeling of inner restlessness and a compelling need to be in Pack sizes are 28 tablets ask them to tell you if they think your depression or anxiety constant motion are the patient): • is getting worse, or if they are worried about changes in your • disorder of the peripheral nerves Marketing Authorisation Holder and Manufacturer: are allergic to amitriptyline or any of the other ingredients of behaviour. • acute increase of pressure in the eye Accord, Barnstaple, EX32 8NS, UK. this medicine (listed in section 6) • particular forms of abnormal heart rhythm (so called This leaflet was last revised in March 2021 • recently have had a heart attack (myocardial infarction) Episodes of mania torsades de pointes) • have heart problems such as disturbances in heart rhythm Some patients with manic-depressive illness may enter into • allergic inflammation of the lung alveoli and of the lung which are seen on an electrocardiogram (ECG), heart block, a manic phase. This is characterised by profuse and rapidly tissue. If you would like a leaflet or coronary artery disease changing ideas, exaggerated gaiety and excessive physical • are taking medicines known as monoamine oxidase activity. In such cases, it is important to contact your doctor Not known (frequency cannot be estimated from the inhibitors (MAOIs) who probably will change your medication. available data): with larger text, please • have taken MAOIs within the last 14 days. If you are treated Tell your doctor if you have, or have had in the past, any • absent sensation of appetite with Amitriptyline tablets you have to stop taking this • elevation or lowering of blood sugar levels contact 01271 385257. medical problems, especially if you have: medicine and wait for 14 days before you start treatment • narrow angle glaucoma (loss of vision due to abnormally • paranoia with a MAOI • movement disorders (involuntary movements or decreased high pressure in the eye) • have taken moclobemide the day before • epilepsy, a history of convulsions or fits movements) • have a severe liver disease.
Load more

Recommended publications
  • List of New Drugs Approved in India from 1991 to 2000
    LIST OF NEW DRUGS APPROVED IN INDIA FROM 1991 TO 2000 S. No Name of Drug Pharmacological action/ Date of Indication Approval 1 Ciprofloxacin 0.3% w/v Eye Indicated in the treatment of February-1991 Drops/Eye Ointment/Ear Drop external ocular infection of the eye. 2 Diclofenac Sodium 1gm Gel March-1991 3 i)Cefaclor Monohydrate Antibiotic- In respiratory April-1991 250mg/500mg Capsule. infections, ENT infection, UT ii)Cefaclor Monohydrate infections, Skin and skin 125mg/5ml & 250mg/5ml structure infections. Suspension. iii)Cefaclor Monohydrate 100mg/ml Drops. iv)Cefaclor 187mg/5ml Suspension (For paediatric use). 4 Sheep Pox Vaccine (For April-1991 Veterinary) 5 Omeprazole 10mg/20mg Short term treatment of April-1991 Enteric Coated Granules duodenal ulcer, gastric ulcer, Capsule reflux oesophagitis, management of Zollinger- Ellison syndrome. 6 i)Nefopam Hydrochloride Non narcotic analgesic- Acute April-1991 30mg Tablet. and chronic pain, including ii)Nefopam Hydrochloride post-operative pain, dental 20mg/ml Injection. pain, musculo-skeletal pain, acute traumatic pain and cancer pain. 7 Buparvaquone 5% w/v Indicated in the treatment of April-1991 Solution for Injection (For bovine theileriosis. Veterinary) 8 i)Kitotifen Fumerate 1mg Anti asthmatic drug- Indicated May-1991 Tablet in prophylactic treatment of ii)Kitotifen Fumerate Syrup bronchial asthma, symptomatic iii)Ketotifen Fumerate Nasal improvement of allergic Drops conditions including rhinitis and conjunctivitis. 9 i)Pefloxacin Mesylate Antibacterial- In the treatment May-1991 Dihydrate 400mg Film Coated of severe infection in adults Tablet caused by sensitive ii)Pefloxacin Mesylate microorganism (gram -ve Dihydrate 400mg/5ml Injection pathogens and staphylococci). iii)Pefloxacin Mesylate Dihydrate 400mg I.V Bottles of 100ml/200ml 10 Ofloxacin 100mg/50ml & Indicated in RTI, UTI, May-1991 200mg/100ml vial Infusion gynaecological infection, skin/soft lesion infection.
    [Show full text]
  • Table 2. 2012 AGS Beers Criteria for Potentially
    Table 2. 2012 AGS Beers Criteria for Potentially Inappropriate Medication Use in Older Adults Strength of Organ System/ Recommendat Quality of Recomm Therapeutic Category/Drug(s) Rationale ion Evidence endation References Anticholinergics (excludes TCAs) First-generation antihistamines Highly anticholinergic; Avoid Hydroxyzin Strong Agostini 2001 (as single agent or as part of clearance reduced with e and Boustani 2007 combination products) advanced age, and promethazi Guaiana 2010 Brompheniramine tolerance develops ne: high; Han 2001 Carbinoxamine when used as hypnotic; All others: Rudolph 2008 Chlorpheniramine increased risk of moderate Clemastine confusion, dry mouth, Cyproheptadine constipation, and other Dexbrompheniramine anticholinergic Dexchlorpheniramine effects/toxicity. Diphenhydramine (oral) Doxylamine Use of diphenhydramine in Hydroxyzine special situations such Promethazine as acute treatment of Triprolidine severe allergic reaction may be appropriate. Antiparkinson agents Not recommended for Avoid Moderate Strong Rudolph 2008 Benztropine (oral) prevention of Trihexyphenidyl extrapyramidal symptoms with antipsychotics; more effective agents available for treatment of Parkinson disease. Antispasmodics Highly anticholinergic, Avoid Moderate Strong Lechevallier- Belladonna alkaloids uncertain except in Michel 2005 Clidinium-chlordiazepoxide effectiveness. short-term Rudolph 2008 Dicyclomine palliative Hyoscyamine care to Propantheline decrease Scopolamine oral secretions. Antithrombotics Dipyridamole, oral short-acting* May
    [Show full text]
  • Switching from Clonidine Immediate-Release to Guanfacine Extended-Release
    / DE L’ACADÉMIE CANADIENNE DE PSYCHIATRIE DE L’ENFANT ET DE L’ADOLESCENT PSYCHOPHARMACOLOGY Switching from Clonidine Immediate-Release to Guanfacine Extended-Release Dean Elbe PharmD, BCPP1,2,3 s a clinical pharmacy specialist in child and adolescent (Canada) Ltd, 2012b). Clonidine has been used off-label Amental health, I am frequently asked how to switch in children for many years for treatment of insomnia, patients from clonidine immediate-release (IR) to guanfa- ADHD, and disruptive behaviour disorders (Hunt, Capper cine extended-release (XR). This therapeutic switch may be & O’Connell, 1990; Rubinstein; Jaselskis, Cook, Fletcher required when poor adherence to a clonidine IR regimen & Leventhal, 1992; Silver & Licamele, 1994; Palumbo et (typically requiring 3–4 doses daily) is identified, when al., 2008; Efron, Lycett & Sciberras, 2014). A clonidine XR clonidine dose-optimization is limited by sedation, brady- formulation is not available in Canada, but is available in cardia or hypotension, or when coverage situations change. the United States for treatment of ADHD (Concordia Phar- The latter may occur if, for example, new eligibility for a maceuticals, Inc. 2015). government program or a third party-payer occurs. Weight-based dosing guidelines exist for clonidine IR Guanfacine XR, a selective alpha2A agonist, was first mar- (0.003–0.008 mg/kg/day) and guanfacine XR (0.05–0.08 keted in Canada in late 2013 for the treatment of attention mg/kg/day) (Shire Pharma Canada ULC, 2019; Elbe et deficit hyperactivity disorder (ADHD) in children and ado- al., 2018). Based on these guidelines and other literature, lescents (Shire Pharma Canada ULC, 2019).
    [Show full text]
  • Research Article RP-HPLC Method for Determination of Several Nsaids and Their Combination Drugs
    Hindawi Publishing Corporation Chromatography Research International Volume 2013, Article ID 242868, 13 pages http://dx.doi.org/10.1155/2013/242868 Research Article RP-HPLC Method for Determination of Several NSAIDs and Their Combination Drugs Prinesh N. Patel, Gananadhamu Samanthula, Vishalkumar Shrigod, Sudipkumar C. Modh, and Jainishkumar R. Chaudhari Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Andhra Pradesh 500037, India Correspondence should be addressed to Gananadhamu Samanthula; [email protected] Received 29 June 2013; Accepted 13 October 2013 Academic Editor: Andrew Shalliker Copyright © 2013 Prinesh N. Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. An RP-HPLC method for simultaneous determination of 9 NSAIDs (paracetamol, salicylic acid, ibuprofen, naproxen, aceclofenac, diclofenac, ketorolac, etoricoxib, and aspirin) and their commonly prescribed combination drugs (thiocolchicoside, moxifloxacin, clopidogrel, chlorpheniramine maleate, dextromethorphan, and domperidone) was established. The separation was performed on ∘ Kromasil C18 (250 × 4.6 mm, 5 m) at 35 C using 15 mM phosphate buffer pH 3.25 and acetonitrile with gradient elution ata flow rate of 1.1 mL/min. The detection was performed by a diode array detector (DAD) at 230 nm with total run time of 30min. 2 Calibration curves were linear with correlation coefficients of determinationr ( ) > 0.999. Limit of detection (LOD) and Limit of quantification (LOQ) ranged from 0.04 to 0.97 g/mL and from 0.64 to 3.24 g/mL, respectively.
    [Show full text]
  • Information About Cough Medicine (DXM)
    Myth: Abusing Over-The-Counter Drugs Are Safe Vancouver Island Information Teens may mistakenly believe that cough Youth & Family medicines sold in stores are less dangerous than about Cough street drugs. Even parents may underestimate Addiction Services the seriousness of DXM abuse and feel relief Medicine (DXM) that their children are "only abusing cough syrup, not illegal drugs." Although cough What is Dextromethorphan (DXM)? medicine is sold in stores and is a regulated product, the reality is that taking large quantities of DXM has the potential to be extremely Dextromethorphan (DXM) is a cough dangerous and even fatal. When taken in suppressant ingredient contained in over-the-counter medicines. combination with other medicines or illicit drugs DXM is found the risk increases significantly. in more than 100 over-the-counter If A Teen Is Using cough and cold medications in syrup, tablet, lozenge Sit down with the youth and openly voice your and capsule form. Taken in suspicions but avoid direct accusations. Do not suggested doses, DXM is have this conversation when the youth is under generally a safe and the influence of a substance. Stay calm and effective rational. cough medication. Seek medical attention immediately if the youth is unresponsive to your voice, vomiting, very Dextromethorphan is found in over-the-counter pale or has a bluish tinge to the skin. cough medicines, including Alka-Seltzer Plus Cold and Cough, Dimetapp DM, For More Information Sudafed cough medicine, Robitussin, Tylenol Cough and Cold medicine, Vicks 44 Cough To find out about services in your community, Relief medicine and many more.
    [Show full text]
  • AMANTADIP\Dle: on Nemolebtic-II[WDUCED CATALEPSY UV the RAT
    J. Fac. Plmnz. Istanbul lstanbul Ecz. Fak. Mec. 29, 1 (1993) 29, 1 (1993) THE EFFECT OF CYPROHEPT~~AWEb AMANTADIP\dlE: ON NEmOLEBTIC-II[WDUCED CATALEPSY UV THE RAT SUMMARY Catalepsy is not a unitary phenomenon. With respect to biochemical mechanisms and neurotransmitter sytems, the origin of this behavioural response varies according to different substances which cause catalepsy. For example, the catdeptogenic effect of ne- uroleptics has been related to the blockage of striatal doparnine receptors. Neurophysio- logical and biochemical data have shown that a mechanism caused by gama-aminobuty- ric acid and serotonin have been effective in the proper functioning of the dopaminergic nigrosbriatal tract. We have studied the effects of cyproheptadine, a serotonin antagonist, and of amantadin which is used in the treatment of Parkinson syndrome on the catalepsy indu- ced by trifluoperazine, a phenothiazin compound, and pimozid, a drug used as a neuro- leptic. It was observed that when rats were pretreated with cyproheptadine as well as amantadiie, the catalepsy induced by the above neuroleptic drugs was attenuated. The results of our study show that substances which have an effect on the seroto- nergic and dopaminergic systems also play a role on cases of catalepsy induced by the neuroleptic drugs mentioned above. (*) Faculty of Pharmacy, Depament of Pharmacology, University of Istanbul, 31152, Istanbul, Turkey Katalepsi bir tek nedene bagh OWortaya qllian bit durum degildir. Biyokimya- sal ve norotransmitter sistemler agsmdan bu davran~glnsebebi, katalepsi olughYan qe- gitli maddeler iqin fad&&. Omegin noroleptiklerin kataleptojenik etkisi striatal dopa- min reseptorlerinin blokaj~nabajjlanmqtx. Niirofizyolojik ve biyokimyasal veriler do- pamine jik nigro-striatal sistemin duzenli $&$masmda gma-aminobutirik asid ve sero- tonin'e bagh olan bir mekanizmmn etkili oldugunu gostermigtir.
    [Show full text]
  • Medication: Amitriptyline 10 Mg
    Amitriptyline (Elavil) COMPLEX CHRONIC DISEASES PROGRAM Medication Handout Date: May 15, 2018 Medication: Amitriptyline 10 mg What is Amitriptyline? Amitriptyline belongs to a group of medications called tricyclic antidepressants (TCAs) that were first used to treat depression. It works by altering the levels of certain neuro- transmitters in the brain such as noradrenalin and serotonin. They have since been found to be effective for many different uses such as: pain, helping with sleep quality (but is not a sleeping pill), irritable bowel syndrome (with diarrhea), migraine prevention, and interstitial cystitis. Expected Benefit: Usually takes several weeks to notice a benefit You may not notice a benefit until you get to a dose of 25 mg Watch for possible side effects: This list of side effects is important for you to be aware of; however, it is also important to remember that not all side effects happen to all people. Many of these less serious side effects will improve over the first few days of taking the medications. If you have problems with these side effects talk with your doctor or pharmacist: Dry mouth – this is the most common side; the others are much less frequent Hangover effect – too sleepy in the morning Blurred vision Urinary retention, trouble with urination Tiredness, dizziness that is more than usual Diarrhea or constipation Stopping the medication: Do NOT stop taking this medication suddenly without asking your doctor – this medication is usually decreased slowly (at higher doses) before it is stopped completely How to use this medication: Take this medication with or without food Dosing Schedule: Start with 5 mg (½ tablet) 2 hrs before bed Increase dose according to table below Many patients can only tolerate 20 or 30 mg If you don’t have dry mouth or side effects, you can continue slowly increasing the dose to a maximum of 70 mg You can stay at a lower dose (stop increasing) if you get side effects (usually dry mouth).
    [Show full text]
  • Traveler's Diarrhea
    THE PRE-TRAVEL CONSULTATION Dr. Becky Reece, MD Lead physician at Lifespan Center of Excellence for Tick-borne Diseases Newport Hospital May 6, 2017 Some Slides from Dr. Kojic, Director of The Miriam Hospital Travel clinic Overview Epidemiology General recommendations The traveller Diseases Diarrhea Vector and animal bite prevention Immunizations Other travel related recommendations Travelers’ Health Risks Of 100,000 travelers to a developing country for 1 month: 50,000 will develop some health problem 8,000 will see a physician 5,000 will be confined to bed 1,100 will be incapacitated in their work 300 will be admitted to hospital 50 will be air evacuated 1 will die Among more than 42,000 ill returned travelers seen between 2007 and 2011 in the GeoSentinel surveillance network, the most common syndromic diagnoses were: gastrointestinal (34%) febrile illnesses (23%) dermatologic illnesses (19%) Asia (32%) and sub-Saharan Africa (25%) were the most common regions where illnesses were acquired. Approximately 40 percent of ill travelers reported pretravel medical visits. Travelers visiting friends and relatives in their country of origin had a disproportionately high burden of serious febrile illness and very low rate of advice prior to travel. Steffen R et al. J Infect Dis 1987. 156:84-91 GeoSentinel Surveillance of Illness in Returned Travelers, 2007–2011Leder K, Torresi J, Libman MD, et al Ann Intern Med. 2013;6(158):456. Causes of death Cardiovascular deaths 49% Cardiovascular Injuries, accidents 22% Medical Injury top on list Egypt, Kenya, Homicide/Suicide India Infectious Disease Other Medical illnesses 13.7% Infectious causes 1% Other Hargarten S et al, Ann Emerg Med, 1991.
    [Show full text]
  • Delusional Parasitosis Mimicking Cutaneous Infestation in Elderly Patients
    LESSONS FROM PRACTICE LESSONS FROM PRACTICE Delusional parasitosis mimicking cutaneous infestation in elderly patients Clinical records Patient 1 Patient 3 An 88-year-old man gave a 12-month history of seeing insects attacking An 81-year-old woman was referred with a persistent belief that his legs and crawling along the floor of his house. He described these she had scabies and lice infestation of her eyes, nose, arms and insects as 4 cm long, black and white bugs with beaks, which pecked anus. This resulted in her persistently washing her clothes and at hisThe legs, Medical causing Journal wounds. of He Australia often felt ISSN:a sharp 0025-729X stinging sensation 18 herself and reporting the retirement village where she lived to the heraldingAugust their 2003 presence. 179 4 209-210 He also had burning pain in both legs below Health Department. She had received anti-scabies treatment the knees. He had had his house fumigated twice in the previous year empirically. ©The Medical Journal of Australia 2003 www.mja.com.au andLessons put various from chemicals practice across his doorways and bed to ward off the She had a long history of severe depression after the death of her bugs. He described no other hallucinations or delusions. husband, for which she took doxepin. She had paranoid ideation He was not using any regular medications and had never been a about her neighbours and saw things crawling down the walls, consumer of alcohol. He lived alone and managed all activities of and had moved residences several times to avoid these problems.
    [Show full text]
  • Drug Use Evaluation: Antipsychotic Utilization in Schizophrenia Patients
    © Copyright 2012 Oregon State University. All Rights Reserved Drug Use Research & Management Program Oregon State University, 500 Summer Street NE, E35 Salem, Oregon 97301-1079 Phone 503-947-5220 | Fax 503-947-1119 Drug Use Evaluation: Antipsychotic Utilization in Schizophrenia Patients Research Questions: 1. How many schizophrenia patients are prescribed recommended first-line second-generation treatments for schizophrenia? 2. How many schizophrenia patients switch to an injectable antipsychotic after stabilization on an oral antipsychotic? 3. How many schizophrenia patients are prescribed 2 or more concomitant antipsychotics? 4. Are claims for long-acting injectable antipsychotics primarily billed as pharmacy or physician administered claims? 5. Does adherence to antipsychotic therapy differ between patients with claims for different routes of administration (oral vs. long-acting injectable)? Conclusions: In total, 4663 schizophrenia patients met inclusion criteria, and approximately 14% of patients (n=685) were identified as treatment naïve without claims for antipsychotics in the year before their first antipsychotic prescription. Approximately 45% of patients identified as treatment naïve had a history of remote antipsychotic use, but it is unclear if antipsychotics were historically prescribed for schizophrenia. Oral second-generation antipsychotics which are recommended as first-line treatment in the MHCAG schizophrenia algorithm were prescribed as initial treatment in 37% of treatment naive patients and 28% of all schizophrenia patients. Recommended agents include risperidone, paliperidone, and aripiprazole. Utilization of parenteral antipsychotics was limited in patients with schizophrenia. Overall only 8% of patients switched from an oral to an injectable therapy within 6 months of their first claim. Approximately, 60% of all schizophrenia patients (n=2512) had claims for a single antipsychotic for at least 12 continuous weeks and may be eligible to transition to a long-acting injectable antipsychotic.
    [Show full text]
  • Schizophrenia Care Guide
    August 2015 CCHCS/DHCS Care Guide: Schizophrenia SUMMARY DECISION SUPPORT PATIENT EDUCATION/SELF MANAGEMENT GOALS ALERTS Minimize frequency and severity of psychotic episodes Suicidal ideation or gestures Encourage medication adherence Abnormal movements Manage medication side effects Delusions Monitor as clinically appropriate Neuroleptic Malignant Syndrome Danger to self or others DIAGNOSTIC CRITERIA/EVALUATION (PER DSM V) 1. Rule out delirium or other medical illnesses mimicking schizophrenia (see page 5), medications or drugs of abuse causing psychosis (see page 6), other mental illness causes of psychosis, e.g., Bipolar Mania or Depression, Major Depression, PTSD, borderline personality disorder (see page 4). Ideas in patients (even odd ideas) that we disagree with can be learned and are therefore not necessarily signs of schizophrenia. Schizophrenia is a world-wide phenomenon that can occur in cultures with widely differing ideas. 2. Diagnosis is made based on the following: (Criteria A and B must be met) A. Two of the following symptoms/signs must be present over much of at least one month (unless treated), with a significant impact on social or occupational functioning, over at least a 6-month period of time: Delusions, Hallucinations, Disorganized Speech, Negative symptoms (social withdrawal, poverty of thought, etc.), severely disorganized or catatonic behavior. B. At least one of the symptoms/signs should be Delusions, Hallucinations, or Disorganized Speech. TREATMENT OPTIONS MEDICATIONS Informed consent for psychotropic
    [Show full text]
  • Memory Deficits Associated with Clonidine
    Letter to the Editor Letters to the Editor are invited for comment on a topic of current interest or on Table material published in GENERAL HOSPITAL PSYCHIATRY. Letters should be typed doubled spaced and are subject to editing according to space limitations. - Memory Deficits Associated with Attent KnO Clonidine WA Verbal WA Drugs used in the treatment of essential hyperten- Initiation of clonidine therapy (0.1 mg b.i.d.) in WA sion are among the most commonly prescribed. April 1984 resulted in well-controlled hypertension Tactilc Some of these agents have primary effects on neu- without immediately apparent adverse effects. Fulc rotransmitter systems and are centrally active. However, the coincidence of the onset of memory Verba Thus, drugs such as a-methyldopa, propranalol, complaints and the beginning of clonidine treat- 3% ment suggested that clonidine might be respon- List Ll and reserpine have well-established neuropsychia- Fulc tric complications, ranging from depression to cog- sible. si nitive impairments and psychosis [l].Since the use After consultation with the patient's internist, a R of these drugs is widespread and unavoidable, we switch was made to captopril, an angiotensin-con- T must be alert to the possibility that these drugs verting enzyme inhibitor. Before the change we T administered tests of attention, concentration, and contribute to psychologic complaints and symp- -R toms of our patients. verbal skills as well as the Fuld Object-Memory Evaluation, which includes a measure of verbal 'Age-a Clonidine, a presynaptic adrenergic a2agonist, bNonc has become well established as a useful and rela- fluency as well as a selective reminding list learning tively safe therapeutic agent.
    [Show full text]