2th International Cardionephrology and Hypertension Congress Cardionephrology Today Programme
May 7-9, 2015. Niš, Serbia
KARNEF 2015
2nd International Cardionephrology and Hypertension Congress “Cardionephrology Today”
P r o g r a m m e
May 7-9, 2015. Niš “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
Contents
Welcome Letter of President of Organizing Committee 3
Honourable Committee 4
Scientific Committee 5
Organizing Committee 6
Meeting Secretariat 6
International Advisory Committee 6
Invited Lecturers 7
Scientific Programme 9
Social Programme 25
General Information 26
Sponsors 28 “Cardionephrology Today”
May 7-9, 2015, Niš
Prof. Dr. Sonja Radenkovic President of Organizing Committee
3 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
th 2nd In2terna Internationaltional Cardionephrology Cardionephrologyand Hypertension and Congr Hypertensioness Congress
HONOURABLE COMMITTEE
Prof. Dr. Srđan Verbić Ministar of Education, Science and Technological Development, Serbia
Prof. Dr. Dragan Antić Rector of the University of Niš
Prof. Dr. Stevan Ilić Meeting Secretariat Dean of the Medical Faculty, University of Niš Nikola Radenković Marija Predić Prof. Dr. Dobrila Stanković Đorđević Jelena Radović Associate Dean of the Medical Faculty, Marija Savković University of Niš Snežana Milošević Dalibor Veličković Prof. Dr. Zoran Radovanović Director of Clinical Center Niš Tijana Predić Associate Dean of the Medical Faculty, University of Niš International Advisory Committee Prof. Dr. Werner Siems Dr. Vesna Jovanović Director of the Serbian Medical Chamber Prof. Dr. Gerard London Prof. Dr. Zorana Vasiljević 4 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
2th International Cardionephrology and Hypertension Congress
SCIENTIFIC COMMITTEE
Prof. Dr. Mario Timio, Perugia, Italy- President
Prof. Dr. Donald Silverberg, Tel Aviv, Israel
Prof. Dr. Volker Wizemann, Giessen, Germany
Prof. Dr. Peter Kotanko, New York, USA
Prof. Dr. Gordana Kocić, Niš, Serbia Meeting Secretariat Nikola Radenković Prof. Dr. Marina Deljanin Ilić, Niš, Serbia Marija Predić Prof. Dr. Rok Accetto, Ljubljana, Slovenia Jelena Radović Marija Savković Prof. Dr. Rafael Ponikvar, Ljubljana, Slovenia Snežana Milošević Prof. Dr. Radovan Hojs, Maribor, Slovenia Dalibor Veličković Prof. Dr. Claudio Ronco, Vicenza, Italy Tijana Predić
Dr. Rodolfo Rivera, Monca, Italy International Advisory Committee Dr. Luca Di Lullo, Rome, Italy Prof. Dr. Werner Siems Prof. Dr. Sonja Radenković, Niš, Serbia Prof. Dr. Gerard London Prof. Dr. Zorana Vasiljević 5 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
2th International Cardionephrology and Hypertension Congress
ORGANIZING COMMITTEE
Prof. Dr. Sonja Radenković, Niš, Serbia - President
Prof. Dr. Radovan Hojs, Maribor, Slovenia
Prof. Dr. Jadranka Buturović Ponikvar, Ljubljana, Slovenia Meeting Secretariat Prof. Dr. Vladmila Bojanić, Niš, Serbia Nikola Radenković Marija Predić Prof. Dr. Slavimir Veljković, Niš, Serbia Jelena Radović Marija Savković Assist. Dr. Dijana Stojanović, Niš, Serbia Snežana Milošević Dalibor Veličković Dr. Predrag Vuksanović, Niš, Serbia Tijana Predić
Dr. Vojin Kalezić, Niš, Serbia International Advisory Committee Prof. Dr. Werner Siems Prof. Dr. Gerard London Prof. Dr. Zorana Vasiljević 6 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
Invited Lecturers
Prof. Dr. Slobodan Antić, Niš, Serbia Prof. Dr. Vladmila Bojanić, Niš, Serbia Prof. Dr. Tatjana Cvetković, Niš, Serbia Prof. Dr. Nebojša Despotović, Belgrade, Serbia Prof. Dr. Radoje Ilić, Belgrade, Serbia Prof. Dr. Gordana Kocić, Niš, Serbia Prof. Dr. Goran Koraćević, Niš, Serbia Prof. Dr. Jasmina Marković Lipkovski, Belgrade, Serbia Assist. Prof. Nataša Marković Nikolić, Belgrade, Serbia Prof. Dr. Branislav Milovanović, Belgrade, Serbia Assist. Prof. Branka Mitić, Niš, Serbia Prof. Dr. Milan Pavlović, Niš, Serbia Gordana Peruničić Peković, MD, PhD, Belgrade, Serbia Prof. Dr. Mileta Poskurica, Kragujevac, Serbia Prof. Dr. Milica Prostran, Belgrade, Serbia Prof. Dr. Sonja Radenković, Niš, Serbia Prof. Dr. Radmila Veličković Radovanović, Niš, Serbia Zorica Rašić, MD, PhD, Belgrade, Serbia Assist. Dr. Dijana Stojanović, Niš, Serbia
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Invited Lecturers
Prof. Dr. Mario Timio, Perugia, Italy
Prof. Dr. Donald Silverberg, Tel Aviv, Israel
Prof. Dr. Volker Wizemann, Giessen, Germany
Prof. Dr Peter Kotanko, New York, USA
Prof. Dr. Bernard Weber, Lausanne, Switzerland
Prof. Dr. Claudio Ronco, Vicenza, Italy
Dr. Luca Di Lullo, Rome, Italy
Dr. Rodolfo Rivera, Monza, Italy
Prof. Dr. Rok Accetto, Ljubljana, Slovenia
Prof. Dr. Radovan Hojs, Maribor, Slovenia
Prof. Dr. Robert Ekart, Maribor, Slovenia
Assist. Prof. Sebastjan Bevc, Maribor, Slovenia
Prof. Dr. Dejan Dinevski, Maribor, Slovenia
Prof. Dr. Rafael Ponikvar, Ljubljana, Slovenia
Prof. Dr. Jadranka Buturović Ponikvar, Ljubljanja, Slovenia
Assist. Dr. Marko Gričar, Ljubljana, Slovenia
Assist. Prof. Marjan Bosevski, Skopje, FYRM
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May 7-9, 2015, Niš
May 7, Amphitheatre A0 Programme
08:00 - 11:00 Registration of participants
11:00 - 11:30 Prof. Dr. Mario Timio Introduction Cardionephrology Today
11:3016:45 -- 17:0012:30 Mini symposium Cardionephrology in everyday clinical practice- differences in approach and problems Assist. Dr. Dijana Stojanović Case report
Assist. Dr. Marko Gričar When and why should cardiologists worry about kidney function in heart failure?
Prof. Dr. Mileta Poskurica Cardiorenal syndrome-why is the ball still in the nephrologist's yard?
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May 7-9, 2015, Niš
May 7, Amphitheatre A0 Programme
12:30 - 14:00 Education Seminar Diagnostics of associated heart disease and kidney-challenges and dilemmas Prof. Dr. Gordana Kocić Assist. Dr. Dijana Stojanović Biomarkers in kidney and heart disease
Prof. Dr. Jasmina Marković Lipkovski Importance of neural cell adhesion molecules (NCAM) expression on renal interstitial cells for development of renal fibrosis
Prof. Dr. Dejan Dinevski Decision support systems in medicine and the example of patients' health evaluation by a hierarchical-multi-attribute decision model
14:00 - 15:00 Lunch break
15:00 - 16:00 POSTER SESSION I (5 minutes per presentation) Chairman Prof. Dr. Nebojša Despotović
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May 7-9, 2015, Niš
May 7, Amphitheatre A0 Programme
16:00 - 16:30 Plenary lecture Prof. Dr. Donald Silverberg Cardiorenal anemia syndrome and role of intravenous iron in its treatment Introduction Prof. Dr. Radovan Hojs
16:30 - 17:15 Opening ceremony and concert
17:15 - 18:30 Welcome cocktail reception
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May 8, Amphitheatre A0 Programme
SESSION I 08:30 - 10:15 ETIOPATHOGENETIC AND PROGNOSTIC ASPECTS OF CARDIORENAL SYNDROME
Working Committee Prof. Dr. Mario Timio Prof. Dr. Jadranka Buturović Ponikvar Prof. Dr. Milan Pavlović
Prof. Dr. Milan Pavlović 08:30 - 08:50 Heart failure and renal dysfunction
Prof. Dr. Rok Accetto 08:50 - 09:10 Hypertensive crisis as a cause dysfunction of the heart and kidneys
Prof. Dr. Sonja Radenković 09:10 - 09:30 Use of diuretics in the treatment of primary generated cardiorenal syndrome - new light on an old problem
Prof. Dr. Nebojša Despotović 09:30 - 09:50 Why is age an independent risk factor in prognosis of cardiorenal syndrome?
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May 7-9, 2015, Niš
May 8, Amphitheatre A0 Programme
Assist. Prof. Sebastjan Bevc 09:50 - 10:10 Renal function and percutaneous coronary interventions
10:10 - 10:15 Discussion
SESSION II 10:15 - 11:40 CURRENT ASPECTS OF DIAGNOSTICS IN ASSOCIATED DISEASE OF HEART AND KIDNEY
Working Committee Jochen Raimann, MD, PhD Prof. Dr. Rok Accetto Prof. Dr. Branislav Milovanović
Prof. Dr. Tanja Cvetković 10:15 - 10:35 The importance of acute kidney damage markers in the assessment of the risk of secondary alteration of the heart
Assist. Prof. Nataša Marković Nikolić 10:35 - 10:55 The specificity of the echocardiographic findings in patients with cardiorenal syndrome
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May 7-9, 2015, Niš
May 8, Amphitheatre A0 Programme
Prof. Dr. Branislav Milovanović 10:55 - 11:15 Functional diagnostics of the autonomic nervous system in primary heart disease
Dr. Biserka Tirmenštajn Janković 11:15 - 11:35 Prognostic significance of B-type natriuretic peptide for fatal and non-fatal cardiovascular events in asymptomatic, predialysis patients
11:35 - 11:40 Discussion
11:40 - 12:00 Break
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May 7-9, 2015, Niš
May 8, Amphitheatre A0 Programme
12:00 - 13:05 SESSION III ACUTE KIDNEY INJURY AND HEART
Working Committee Prof. Dr. Robert Ekart Prof. Dr. Radmila Veličković Radovanović Prof. Dr. Goran Koraćević
Prof. Dr. Peter Kotanko (Jochen Raimann, MD, PhD) 12:00 - 12:20 Cardiovascular events in patients with acute renal injury treated on hemodialysis
Prof. Dr. Jadranka Buturović Ponikvar 12:20 - 12:40 Acute kidney injury in renal transplant recipients and risk factors
Prof. Dr. Radoje Ilić 12:40 - 13:00 Cardiosurgical interventions in hemodialysis patients
13:00 - 13:05 Discussion
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May 7-9, 2015, Niš
May 8, Amphitheatre A0 Programme
POSTER SESSION II (5 minutes per presentation) 13:05 - 14:00 Chairman Assist. Prof. Nataša Marković Nikolić
14:00 - 15:00 Lunch break
SESSION IV 15:00 - 16:30 INNOVATIONS IN THE TREATMENT OF CARDIOVASCULAR DAMAGE IN ACUTE AND CHRONIC KIDNEY DISEASE
Working Committee Prof. Dr. Rafael Ponikvar Prof. Dr. Vladmila Bojanić Prof. Dr. Radoje Ilić
15:00 - 15:20 Prof. Dr. Vladmila Bojanić The role of L-arginine / NO system and folic acid in the protection of heart and vascular structures in patients with chronic renal disease
Prof. Dr. Volker Wizemann 15:20 - 15:40 Composition of the dialysate as an important factor in the CVS damages prevention and treatment in patients on chronic dialysis
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May 7-9, 2015, Niš
May 8, Amphitheatre A0 Programme
Prof. Dr. Rafeal Ponikvar 15:40 - 16:00 Vascular approaches for hemodialysis and cardiovascular complications
Prof. Dr. Milica Prostran 16:00 - 16:20 The place and role of new oral anticoagulants in the treatment of atrial fibrillation in patients with end stage chronic renal disease
16:20 - 16:30 Discussion
16:30 - 16:45 Break
Education Seminar 16:45 - 17:45 Emergencies and cardiorenal damage-etiopathogenetic, diagnostic and therapeutic aspects Prof. Dr. Sonja Radenković Etiopathogenetic aspects of water and electrolytes disorders in emergencies
Prof. Dr. Radmila Veličković Radovanović Prevention and management of acute renal injury in intensive care unit patients
Prof. Dr. Goran Koraćević Prophylaction of acute aortic complications of arterial hypertension 17 “Cardionephrology Today”
May 7-9, 2015, Niš
May 8, Amphitheatre A0 Programme
17:45 - 18:15 Plenary lecture Prof. Dr. Rafael Ponikvar Hemodynamic changes in dialysis patients as a predictor of heart damage Introduction Prof. Dr. Sonja Radenković
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May 9, Amphitheatre A0 Programme
SESSION V 08:30 - 10:40 DIABETES, OBESITY AND CARDIORENAL DAMAGE
Working Committee Prof. Dr. Slobodan Antić Assist. Prof. Sebastjan Bevc Gordana Peković Peruničić, MD, PhD
Prof. Dr. Radovan Hojs 08:30 - 08:50 Obesity and kidney
Prof. Dr. Slobodan Antić 08:50 - 09:10 SGLT2 inhibition and its importance in diabetology, cardiology and nephrology
Zorica Rašić, MD, PhD 09:10 - 09:30 Albuminuria - a cause or a consequence of cardiorenal damage in patients with metabolic syndrome
Prof. Dr. Robert Ekart 09:30 - 09:50 Peritoneal dialysis in patients with diabetes mellitus and cardiovascular complications
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May 7-9, 2015, Niš
May 9, Amphitheatre A0 Programme
Assist. Prof. Branka Mitić 09:50 - 10:10 Specifics of cardiovascular damage in diabetic nephropathy
Assist. Prof. Marjan Bosevski 10:10 - 10:30 Peripheral arterial dysfunction, blood urea and dyslipidemia could stratify a risk of patients with arterial hypertension and/or metabolic syndrome
10:30 - 10:40 Discussion
10:40 - 10:50 Break
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May 7-9, 2015, Niš
May 9, Amphitheatre A0 Programme
SESSION VI 10:50 - 12:00 THE ROLE OF HYPERTENSION IN THE CONTINUATION AND PROGRESSION OF CARDIORENAL DAMAGE
Working Committee Dr. Luca Di Lullo Assist. Prof. Marjan Bosevski Dr. Rodolfo Rivera
Prof. Dr. Bernard Weber 10:50 - 11:10 Renin-angiotensin-aldosterone system, pathophysiological aspects and clinical implications in renal and cardiovascular damages
Prof. Dr. Jadranka Buturović Ponikvar 11:10 - 11:30 Renovascular disease and its role in cardiovascular events
Gordana Peković Peruničić, MD, PhD 11:30 - 11:50 Albuminuria significance in patients with arterial prehypertension and hypertension as a cause of possible cardiorenal damage
11:50 - 12:00 Discussion
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May 7-9, 2015, Niš
May 9, Amphitheatre A0 Programme
12:00 - 12:30 Mini Symposium Prof. Dr. Sonja Radenković Are we on a path of a new therapeutic possibilities in the treatment of hypertension and cardiorenal disorders?
12:30 - 12:45 Break
SESSION VII 12:45 - 13:50 HYPERURICEMIA SYNDROME AND CARDIORENAL DAMAGES
Working Committee Prof. Dr. Tatjana Cvetković Assist. Prof. Branka Mitić Zorica Rašić, MD, PhD Prof. Dr. Claudio Ronco (Dr. Luca Di Lullo) 12:45 - 13:05 Hyperuricemia syndrome-patophysiology and therapy
Prof. Dr. Sonja Radenković 13:05 - 13:25 Significance of asymptomatic hyperuricemia in the development and progression of cardiorenal damage
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May 7-9, 2015, Niš
May 9, Amphitheatre A0 Programme
Prof. Dr. Gordana Kocić 13:25 - 13:45 Circulating purine nucleotides, uric acid and oxidative stress in arterial hypertension
13:45 - 13:50 Discussion
13:50 - 14:30 Mini Symposium Dr. Luca Di Lullo, Dr. Rodolfo Rivera What has changed in the understanding of clinical modalities of cardiorenal syndrome from the cardiologists and nephrologists perspective?
14:30 - 14:45 Verifying of acquired knowledge (Test)
14:45 - 15:00 Conclusions and closing of Congress
15:00 - 15:30 Certificates award ceremony
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May 7-9, 2015, Niš
Programme
POSTER SESSION
Dr. Violeta Ranđelović-Krstić Biomarkers in the evaluation of patients with cardiorenal disease Dr. Danijela Tasić Parameters of oxidative stress and cardiorenal syndrome Dr. Dalibor Veličković The effect of acetylsalicylic acid on blood pressure of patients younger than 65 years with hypertension Dr. Siniša Filipović Effects of smoking on blood pressure in people with hypertension Dr. Mirjana Labović Importance of magnesium supplementation in the treatment of primary arterial hypertension Dr. Maja Nakić Albuminuria in patients with primary arterial hypertension Dr. Predrag Vuksanović Sonographic characteristics of ischemic hypertensive nephropathy Dr. Sanja Milutinović Jovanović Etiopathogenic aspects of hyperkalemia in patients with severe extent of ischemic heart disease Dr. Fahrudin Hadrović Microinflammation as a risk factor for a development of a cardiovascular disease in hemodialysis patients Dr. Fahrudin Hadrović Risk assessment of development of contrast- induced nephropathy - case description Dr. Branislav Apostolović Predictive risk factors for cardiovascular mortality in hemodialysis patients Dr. Zorica Dimitrijević Anticoagulant therapy in patients with chronic kidney disease - when and how 24 “Cardionephrology Today”
May 7-9, 2015, Niš
Social Programme
May 7, Thursday; 16:30 Opening ceremony and concert
May 7, Thursday; 17:15 Welcome reception
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May 7-9, 2015, Niš
General Information
Meeting place Ceremony Amphitheatre (A0) at Medical Faculty annex Niš
On-site registration Each participant/company must fill in the on-site registration forms (7-9 May, from 8:00 to 11:00), located at the reception desk. Information such as name, full address, e-mail and fax will be mandatory for each registration, whether personal or sponsored. It will be possible to pay by using bank cheques (already issued) and bank transfers (in which case a copy of the original bank transfer receipt issued by the bank must be handed in while registering) and cash. The registration fee includes admission to the Opening Ceremony and the Welcome Reception, one congress bag with complete meeting materials, unlimited access to all scientific sessions, and certificate. Identification We kindly ask you to carry your ID cards and bags with you during meeting activities. Only with ID card you will be able to enter a meeting room and exhibition space. Attendance certificates Attendance certificates will be delivered on request to all regularly registered participants at the end of the meeting.
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May 7-9, 2015, Niš
General Information
Languages The official language of the Meeting is English. Simultaneous interpretation will not be provided. All presentation slides will be in English. Presentations Oral presentations - duration 20 minutes, including discussion. Slides should be in English, and presentations can be held in English or Serbian. A projector (video beamer) with accompanying equipment will be available. Presentation should be prepared in PowerPoint, using Times New Roman or Arial font. Poster presentations - panels for posters have width of 120 cm and height of 80 cm. Posters should be in English. Poster presentation will be organized in the hall of Faculty (annex). Discussion will be in English and Serbian. Welcome reception The Opening Ceremony of the Congress will be held on May 7, from 16:30 to 17:15, in the Ceremony Amphitheater at the Medical Faculty of Niš. Opening Ceremony will be followed by Welcome Cocktail. No smoking Smoking in the Meeting area will not be allowed. Mobile phones Mobile phones must be switched off during scientific sessions.
27 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš Sponsors MYLAN
ALKALOID
ACTAVIS
PHARMASWISS
PROTON
SANOFI
HEMOFARM
TEVA
MIVELA
STATUS VINARIJA
NAUTILUS IVAGO 28 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
Meeting Organizers
MEDICAL FACULTY NIŠ - Center for Continuing Medical Education
Serbian Cardionephrology Association
By decision of the Serbian Medical Council number 153-02-416/2015-01, 3.3.2015 accredited as the international meeting - number of CME: For lecturers 15 CME, For oral presentation 13 CME, For poster presentations 11 CME, For participants 9 CME.
The Meeting is also accredited by: International Society of Nephrology, International Society of Hypertension and European Cardionephrology Association
Under the Auspices of: Ministry of Education, Science and Technological Development, Serbia
Organizing Committee of “KARNEF 2015” is thankful to all who gave significant support and cooperation
29 “Cardionephrology Today” KARNEF 2015 May 7-9, 2015, Niš
For every further information please contact:
Meeting Secretariat
Snežana Milošević tel. 063 1045034 Marija Savković Nikola Radenković Marija Predić Dalibor Veličković
President of Organizing Committee
Prof. Dr. Sonja Radenković tel. 064 2635009
Medical Faculty, Niš tel. 0 1 8 4226-644 fax 0 1 8 4238-770 www.karnef.org www.medfak.ni.ac.rs
30 “Believe you can and you're halfway there.” Theodore Roosevelt
“Put your heart, mind, and soul into even your smallest acts. This is the secret of success.” Swami Sivananda
”By three methods we may learn wisdom: First, by reflection, which is noblest; Second, by imitation, which is easiest; and third by experience, which is the bitterest.” Confucius
“You can fool all the people some of the time, and some of the people all the time, but you cannot fool all the people all the time.” Abraham Lincoln
“Pleasure in the job puts perfection in the work.” Aristotle
KARNEF 2015 NOTES
2nd International Cardionephrology and Hypertension Congress “Cardionephrology Today”