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Concepts and Big Idea Essential Question Competencies Timeline Describe the characteristics of life shared by all prokaryotic and Nature of Science share common How do we know if eukaryotic organisms 2 cycles (Note: 1 characteristics of life. something is alive? cycle = 6 days) Distinguish between the scientific terms: hypothesis, inference, law, theory, principle, fact, observation Describe the unique properties of water and how these properties Inorganic Chemistry support life on Earth (e.g. freezing point, high specific heat, 2 cycles cohesion)

Describe how biological form from monomers

Describe the role of an as a catalyst in regulating a Life emerges due to the How does life result specific biochemical reaction chemical organization of from chemical structure matter into cells. and function? Organic Chemistry Compare the structure and function of , , 3 cycles and nucleic acids in organisms

Explain how carbon is uniquely suited to form biological macromolecules

Explain how factors such as pH, temperature, and concentration levels can affect enzyme function

Cells have organized structures and systems How does life result Describe how membrane-bound cellular (e.g. necessary to support from cellular structure endoplasmic reticulum,Golgi apparatus) facilitate the transport chemical reactions needed to and function? of materials within a maintain the living condition. Cells 1 cycle Compare cellular structures and their functions in prokaryotic How is structure related and eukaryotic cells Structure is related to to function at all function at all biological biological levels of Describe and interpret relationships between structure and levels of organization. organization? function at various levels of biological organization (i.e. organelles, cells, tissues, organs, systems and multicellular organisms)

Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell Through a variety of How do organisms mechanisms organisms seek maintain a biological to maintain a biological Cell Transport balance between their balance between their 1.7 cycles Compare the mechanisms that transport materials across the internal and external internal and external plasma membrane (i.e. passive transport - diffusion, osmosis, environments? environments. facilitated diffusion; and active transport – pumps, endocytosis, exocytosis)

Explain how organisms maintain (e.g. thermoregulation, water regulation, oxygen regulation) Concepts and Big Idea Essential Question Competencies Timeline

Eukaryotic cells can differentiate and organize What are the advantages Describe the fundamental roles of plastids (e.g. chloroplasts) and making it possible for of multicellularity? 2 cycles mitochondria in transformation multicellularity.

How do different Compare the basic transformation of energy during Organisms obtain and use organisms obtain and Cell Respiration photosynthesis and cellular respiration energy to carry out their life use energy to survive in 1 cycle processes. their environment? Describe the role of ATP in biochemical reactions

Describe how the process of DNA replication results in the Hereditary information in How is the hereditary transmission and/or conservation of genetic information genes is inherited and information in genes expressed. inherited and expressed? Explain the functional, relationships between DNA, genes, DNA/ alleles, and chromosomes and their roles in inheritance Synthesis 2 cycles Describe how the processes of transcription and translation are DNA segments contain similar in all organisms information for the How does DNA control production of proteins growth and function of Describe the role of ribosomes, endoplasmic reticulum, Golgi necessary for growth and cells? apparatus, and the nucleus in the production of specific types of function of cells. proteins

Describe the events that occur during the cell cycle: interphase, New cells arise from the How do cells grow and Cell Division nuclear division (i.e. or ) , cytokinesis division of pre-existing cells. reproduce? 1.5 cycles Compare the processes and outcomes of mitotic and meiotic nuclear divisions

Describe and/or predict observed patterns of inheritance (i.e. Mendelian dominant, recessive, co-dominance, incomplete dominance, sex- 1.3 cycles linked, polygenic, and multiple alleles)

DNA segments contain Describe processes that can alter composition or number of information for the How does DNA control chromosomes (i.e. crossing-over, nondisjunction, duplication, production of proteins growth and function of translocation, deletion, insertion,and inversion) necessary for growth and cells? function of cells. Explain how genetic engineering has impacted the field of Genetics medicine, forensics, and agriculture (e.g. selective breeding, 1.7 cycles gene splicing, cloning, genetically modified organisms, gene therapy)

Describe how genetic alter the DNA sequence and may or may not affect phenotype (e.g. silent, nonsense, frame-shift) Concepts and Big Idea Essential Question Competencies Timeline Explain how can impact allele frequency of a Describe the factors that can contribute to the development of is the result of How do we scientifically new species (e.g. isolating mechanisms, , founder many random processes explain the evidence and Evolution effect, migration) selecting for the survival and mechanisms for 3 cycles Explain how genetic mutations may result in genotypic and of a population. biological evolution? phenotypic variations within a population Interpret evidence supporting the theory of evolution (i.e. fossil, anatomical, physiological, embryological, biochemical, and universal genetic code)

Describe the levels of ecological organization (i.e. organisms, population, , , biome, and )

Describe characteristic biotic and abiotic components of aquatic Organisms on Earth interact How do organisms and terrestrial and depend in a variety of interact and depend on Describe biotic interactions in an ecosystem (e.g. competition, ways on other living and each other and their predation, symbiosis) nonliving things in their environment for environments. survival? 2 cycles Describe how matter recycles through an ecosystem (i.e. water cycle, carbon cycle, oxygen cycle, and nitrogen cycle)

Describe how ecosystems change in response to natural and human disturbances (e.g. climate change, introduction of nonnative species, pollution, fires) How do different Organisms obtain and use organisms obtain and Describe how energy flows through an ecosystem (e.g. food energy to carry out their life use energy to survive in chains, food webs, energy pyramids) processes. their environment?