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C:\Documents and Settings\Williams\Local Settings\Temp Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 1 of 239 UNITED STATES COURT OF FEDERAL CLAIMS IN RE: CLAIMS FOR VACCINE ) INJURIES RESULTING IN ) AUTISM SPECTRUM DISORDER, ) OR A SIMILAR ) NEURODEVELOPMENTAL ) DISORDER ) ----------------------------- ) FRED AND MYLINDA KING, ) PARENTS OF JORDAN KING, ) A MINOR, ) Petitioners, ) v. ) Docket No.: 03-584V SECRETARY OF HEALTH AND ) HUMAN SERVICES, ) Respondent. ) ----------------------------- ) GEORGE AND VICTORIA MEAD, ) PARENTS OF WILLIAM P. MEAD, ) A MINOR, ) Petitioners, ) v. ) Docket No. 03-215V SECRETARY OF HEALTH AND ) HUMAN SERVICES, ) Respondent. ) REVISED AND CORRECTED COPY Pages: 1456 through 1693/1775 Place: Washington, D.C. Date: May 16, 2008 HERITAGE REPORTING CORPORATION Official Reporters 1220 L Street, N.W., Suite 600 Washington, D.C. 20005-4018 (202) 628-4888 [email protected] Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 2 of 239 1456 IN THE UNITED STATES COURT OF FEDERAL CLAIMS OFFICE OF SPECIAL MASTERS IN RE: CLAIMS FOR VACCINE ) INJURIES RESULTING IN ) AUTISM SPECTRUM DISORDER, ) OR A SIMILAR ) NEURODEVELOPMENTAL ) DISORDER ) ----------------------------- ) FRED AND MYLINDA KING, ) PARENTS OF JORDAN KING, ) A MINOR, ) ) Petitioners, ) ) v. ) Docket No.: 03-584V ) SECRETARY OF HEALTH AND ) HUMAN SERVICES, ) ) Respondent. ) ----------------------------- ) GEORGE AND VICTORIA MEAD, ) PARENTS OF WILLIAM P. MEAD, ) A MINOR, ) Petitioners, ) ) v. ) Docket No. 03-215V ) SECRETARY OF HEALTH AND ) HUMAN SERVICES, ) ) Respondent. ) Courtroom 402 National Courts Building 717 Madison Place NW Washington, D.C. Friday, May 16, 2008 The parties met, pursuant to adjournment, at 9:05 a.m. Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 3 of 239 1457 BEFORE: HONORABLE GEORGE L. HASTINGS, JR. HONORABLE PATRICIA E. CAMPBELL-SMITH HONORABLE DENISE VOWELL Special Masters APPEARANCES: For the Petitioners: THOMAS B. POWERS, Esquire MICHAEL L. WILLIAMS, Esquire Williams Love O'Leary & Powers, P.C. 9755 S.W. Barnes Road, Suite 450 Portland, Oregon 97225-6681 (503) 295-2924 For the Respondent: VINCE MATANOSKI, Esquire VORIS E. JOHNSON, JR., Esquire U.S. Department of Justice Civil Division Torts Branch P.O. Box 146 Ben Franklin Station Washington, D.C. 20044-0146 (202) 616-4136 Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 4 of 239 1458 C O N T E N T S VOIR WITNESSES: DIRECT CROSS REDIRECT RECROSS DIRE For the Petitioners: Elizabeth Mumper -- 1460 1625 1669 -- Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 5 of 239 1459 E X H I B I T S RESPONDENT'S EXHIBITS: IDENTIFIED RECEIVED DESCRIPTION Trial Exhibit: 2 1563 -- Letter from N.Y. Department of Health 3 1566 -- Letter from N.Y. Department of Heath, 2006 Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 6 of 239 1460 1 P R O C E E D I N G S 2 (9:05 a.m.) 3 SPECIAL MASTER CAMPBELL-SMITH: We are back 4 on the record. I understand from counsel there are no 5 preliminary matters to be addressed. We are in a 6 position to resume with the cross-examination of Dr. 7 Mumper. 8 Good morning, Dr. Mumper. You continue to 9 be under oath. 10 Whereupon, 11 ELIZABETH MUMPER 12 having been previously duly sworn, was 13 recalled as a witness herein and was examined and 14 testified further as follows: 15 CROSS-EXAMINATION (Resumed) 16 BY MR. JOHNSON: 17 Q Good morning, Doctor. 18 A Good morning. 19 Q When we wrapped up yesterday, we were 20 talking about porphyrin testing, and I want to go back 21 to that issue just briefly. 22 This is not the first time you've testified 23 as an expert in a case involving autism and mercury, 24 is that correct? 25 A That is correct. Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 7 of 239 DR. MUMPER - CROSS ( RESUMED ) 1461 1 Q You testified in a case called Blackwell v. 2 Sigma Aldridge in Baltimore, is that right? 3 A That's correct. 4 Q And do you remember giving a deposition in 5 that case? 6 A Yes, I do. 7 Q And that was in January of 2007? 8 A Yes. 9 Q And you also testified at an evidentiary 10 hearing held in August of 2007, is that right? 11 A That's correct. 12 Q At the hearing, the evidentiary hearing, do 13 you remember being asked about laboratory results for 14 biomarkers that you look for in your patients to 15 determine if they are harmed by mercury? 16 A I'm sure that I was, but it's been so long 17 that I would appreciate it if you would flash the 18 testimony up. 19 Q We'd be happy to. 20 And do you remember testifying, or actually 21 why don't you just read the highlighted portion of 22 your testimony. 23 A "Probably the most helpful test to me now is 24 a porphyrin test, and the reason I like the porphyrin 25 test is that it actually looked at the impact of ethyl Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 8 of 239 DR. MUMPER - CROSS ( RESUMED ) 1462 1 mercury and other heavy metals on body biochemistry 2 and body physiology." 3 I realize now I should have specified the 4 impact of mercury because it does not distinguish 5 ethyl from other forms. 6 Q Is it now your testimony that the porphyrin 7 test is not the most helpful test for determining if 8 your patients are harmed by mercury? 9 A As the science as evolved, we have continued 10 to use other measures also. What we have now that I 11 didn't know about back then are also some inflammatory 12 markers in urine specimens that look for co-existing 13 inflammation, that, in addition, is very helpful, but 14 I do continue to use the porphyrins quite a bit, yes. 15 Q You mentioned testing for inflammatory 16 markers in urine. Who does that testing? 17 A Dr. Nataf's lab does that testing, but we 18 are also able to get it from Metametrix and other labs 19 probably that I don't know of. 20 Q The porphyrin test is a test that you are 21 still ordering in your practice, is that right? 22 A That's correct. 23 Q And it's a test that you are still using to 24 make clinical decisions regarding your patients 25 treatment and care, is that accurate? Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 9 of 239 DR. MUMPER - CROSS ( RESUMED ) 1463 1 A Yes, using it in context with the most 2 important part, which is the history of the child and 3 the clinical appearance of the child. 4 Q You testified yesterday that you could not 5 tell me how long after an exposure you would still 6 consider the porphyrin test to be reliable. 7 A That's correct. 8 Q If you're using the test to make treatment 9 decisions, you must have some idea of when the test is 10 medically appropriate, wouldn't that be correct? 11 A When I use the test, I am looking at the 12 impact of a particular child with regard to impact on 13 a very crucial biochemical pathway at the time that I 14 get that child. I don't have the advantage of getting 15 him or her at a time that I can choose with regard to 16 any exposures, and often I am trying to figure out 17 what the exposures are. 18 So, I think we have already established that 19 I'm not a toxicologist, so I don't want to venture 20 beyond my area of expertise to speculate about how 21 that test is constructed in terms of the question that 22 counsel asked me. But I am still able to use it, I 23 think, as a clinically valuable tool as long as I use 24 it in the context of the individual patient, the 25 clinical history, and other supporting laboratory data Heritage Reporting Corporation (202) 628-4888 Case 1:03-vv-00584-MBH Document 119 Filed 10/23/08 Page 10 of 239 DR. MUMPER - CROSS ( RESUMED ) 1464 1 that might be consistent with what I see on the 2 porphyrin test. 3 Q You wouldn't order that test unless it was 4 medically appropriate or clinically indicated, is that 5 accurate? 6 A Unless my judgment was that that was the 7 case, yes. 8 Q And how long after an exposure, in your 9 judgment, would you personally not order a porphyrin 10 test based on a belief that it would no longer be a 11 reliable measure of, or reliable evidence that your 12 patient was harmed by mercury? 13 A I do not have that number and do not wish to 14 speculate about it. 15 Q So you are unwilling to provide me with a 16 timeframe on that question? 17 A No. I'm willing to provide you with any 18 information that I feel is within the realm of my 19 expertise as an clinician. It seems to me that I'm 20 being asked to venture into territory that we've 21 already established through DOJ's help is not my area 22 of expertise, i.e., toxicology and laboratory science.
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