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Autism--Why the Increased Rates? a One-Year Update. Hearings

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Autism--Why the Increased Rates? a One-Year Update. Hearings DOCUMENT RESUME ED 467 484 EC 309 127 TITLE Autism--Why the Increased Rates? A One-Year Update. Hearings before the Committee on Government Reform, House of Representatives, One Hundred Seventh Congress, First Session, April 25 and 26, 2001. INSTITUTION Congress of the U.S., Washington, DC. House Committee on Government Reform. REPORT NO House-Hrg-107-29 PUB DATE 2001-04-00 NOTE 397p. AVAILABLE FROM Superintendent of Documents, U.S. Government Printing Office, Mail Stop: SSOP, Washington, DC 20402-0001. Tel: 202 -512- 1800; Tel: 866-512-1800 (Toll Free); Fax: 202-512-2250. For full text: http://www.gpo.gov/congress/house. PUB TYPE Legal/Legislative/Regulatory Materials (090) EDRS PRICE EDRS Price MFO1 /PC16 Plus Postage. DESCRIPTORS *Autism; Comparative Analysis; Data Analysis; Epidemiology; Etiology; Hearings; *Immunization Programs; *Incidence; *Symptoms (Individual Disorders); *Trend Analysis IDENTIFIERS Congress 107th ABSTRACT These hearings before the House of Representatives Committee on Government Reform address possible reasons for the apparently rapid increase in the incidence of autism. An introduction by the Committee Chairman, Dan Burton, provides background information and suggests a possible linkage between autism and the mumps-measles-rubella vaccine, specifically the possibility of mercury contamination. Text is included of statements from representatives of the following: the Committee on Immunization Safety, Institute of Medicine; National Academy of Sciences; Indiana University School of Medicine; McGill University; MIND Institute, University of California, Davis; National Institute of Child Health and Human Development; Office of Vaccine Research and Review, Food and Drug Administration; Office of Vital Statistics and Epidemiology; and the Center on Birth Defects and Developmental Disabilities. Extensive letters, statements, and other materials are also included. (DB) Reproductions supplied by EDRS are the best that can be made from the original document. AUTISM WHY THEINCREASEDRATES? A ONE- YEAR UPDATE 00 HEARINGS BEFORE THE COMMITTEE ON GOVERNMENT REFORM HOUSE OFREPRESENTATIVES ONE HUNDRED SEVENTH CONGRESS FIRST SESSION APRIL 25 AND 26, 2001 Serial No. 107-29 Printed for the use of the Committee on Government Reform U.S. DEPARTMENT OFEDUCATION Office of Educational Research andImprovement EDUCATIONAL RESOURCESINFORMATION CENTER (ERIC) This document has beenreproduced as received from the person ororganization originating it. Minor changes have been madeto improve reproduction quality. Points of view or opinionsstated in this document do not necessarilyrepresent official OERI position or policy. Available via the World Wide Web:http://www.gpo.gov/congress/house http://www.house.gov/reform U.S. GOVERNMENT PRINTING OFFICE 76-856 PDF WASHINGTON : 2001 For sale by the Superi. indent of Documents, U.S. Government Printing Office Internet: bookstore.gpo.gov Phone: toll free (866) 512-1800; DC area (202) 512-1800 Fax: (202) 512-2250 Mail: Stop SSOP, Washington, DC 20402-0001 O JEST COPY AVAILABLE COMMITTEE ON GOVERNMENT REFORM DAN BURTON, Indiana, Chairman BENJAMIN A. GILMAN, New York HENRY A. WAXMAN, California CONSTANCE A. MORELLA, Maryland TOM LANTOS, California CHRISTOPHER SHAYS, Connecticut MAJOR R. OWENS, New York ILEANA ROS-LEHTINEN, Florida EDOLPHUS TOWNS, New York JOHN M. McHUGH, New York PAUL E. KANJORSKI, Pennsylvania STEPHEN HORN, California PATSY T. MINK, Hawaii JOHN L. MICA, Florida CAROLYN B. MALONEY, New York THOMAS M. DAVIS, Virginia ELEANOR HOLMES NORTON, Washington, MARK E. SOUDER, Indiana DC JOE SCARBOROUGH, Florida ELIJAH E. CUMMINGS, Maryland STEVEN C. LATOURETTE, Ohio DENNIS J. KUCINICH, Ohio BOB BARR, Georgia ROD R. BLAGOJEVICH, Illinois DAN MILLER, Florida DANNY K DAVIS, Illinois DOUG OSE, California JOHN F. TIERNEY, Massachusetts RON LEWIS, Kentucky JIM TURNER, Texas JO ANN DAVIS, Virginia THOMAS H. ALLEN, Maine TODD RUSSELL PLATTS, Pennsylvania JANICE D. SCHAKOWSKY, Illinois DAVE WELDON, Florida WM. LACY CLAY, Missouri CHRIS CANNON, Utah ADAM H. PUTNAM, Florida C.L. "BUTCH" OTTER, Idaho EDWARD L. SCHROCK, Virginia BERNARD SANDERS, Vermont (Independent) KEVIN BINGER, Staff Director DANIEL R. MOLL, Deputy Staff Director JAMES C. WILSON, Chief Counsel ROBERT A. BRIGGs, Chief Clerk PHIL SCHILIRO, Minority Staff Director CONTENTS Page Hearing held on: April 25, 2001 1 April 26, 2001 307 Statement of: Bradstreet, James J., M.D. FAAFP; Cindy Kay Schneider, M.D. FACOG; Jeff Segal, M.D.; and Sharon G. Humiston, M.D. 38 McCormick, Marie, MDSCD, chair, Committee on Immunization Safety Review, Institute of Medicine, accompanied by William Colglazier, exec- utive officer, National Academy of Sciences; and Susanne Stoiber, exec- utive officer 202 McDougle, Christopher J., M.D. Riley Children's Hospital, Indiana Uni- versity School of Medicine; Andrew Wakefield, M.D.. WalterSpitzer, M.D.,M.D. Faculty of Medicine, McGill University, Montreal, Canada; Boyd E. Department of Chemistry, University of Kentucky; David G. Amaral, MIND Institute, University of California, Davis; Dr. Eliza- beth Miller, Public Health Laboratory, England; and Dr. MichaelD. Gershon, Department of Anatomy and Cell Biology, Columbia Univer- sity 89 Rennert, Owen M., M.D., Scientific Director, National Institute of Child Health and Human Development, National Institutes of Health; Karen Midthun, M.D., Director, Office of Vaccine Research and Review, Food and Drug Administration, accompanied by Susan Ellenberg, M.D., Di- rector, Office of Vital Statistics and Epidemiology; NormanBaylor, M.D., Associate Director, Regulatory Policy, Office of Vaccines; and Dr. Colleen Boyle, Acting Associate Director, Science and Public Health, Center on Birth Defects and Developmental Disabilities, Cen- ters for Disease Control and Prevention 314 Smith, Hon. Christopher H., a Representative in Congress from the State of New Jersey; and Hon. Michael F. Doyle, a Representative in Con- gress from the Commonwealth of Pennsylvania 25 Letters, statements, etc.etc., submitted for the record by: Amaral, David G., Institute, University of California, Davis, pre- pared statement of 160 Boyle, Dr. Colleen, Acting Associate Director, Science and Public Health, Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, prepared statement of 354 Burton, Hon. Dan, a Representative in Congress from the State of Indi- ana: Letter dated April 24, 2001 4 Prepared statements of 7, 310 Clay, Hon. Wm. Lacy, a Representative in Congress from the Stateof Missouri, prepared statement of 22 Doyle, Hon. Michael F., a Representative in Congress from the Common- wealth of Pennsylvania, prepared statement of 33 Gershon, Dr. Michael D., Department of Anatomy and Cell Biology, Co- lumbia University, prepared statement of 178 Gilman, Hon. Benjamin A., a Representative in Congress from the State of New York, prepared statement of 378 Haley, Boyd E., Department of Chemistry, University of Kentucky, pre- pared statement of 137 Humiston, Sharon G.,G. M.D., prepared statement of 77 McCormick, Marie, chair, Committee on Immunization Safety Review, Institute of Medicine, prepared statement of 205 Page Letters, statements, etc., submitted for the record byContinued Midthun, Karen, M.D., Director, Office of Vaccine Research and Review, Food and Drug Administration, prepared statement of 336 Miller, Dr. Elizabeth, Public Health Laboratory, England, prepared state- ment of 164 Rennert, Owen M., M.D., Scientific Director, National Institute of Child Health and Human Development, National Institutes of Health, pre- pared statement of 318 Schneider, Cindy Kay, M.D. FACOG, prepared statement of 45 Segal, Jeff, M.D., prepared statement of 68 Smith, Hon. Christopher H., a Representative in Congress from the State of New Jersey, prepared statement of 28 Wakefield, Andrew, M.D., prepared statement of 96 Weldon, Hon. Dave, a Representative in Congress from the State of Florida, prepared statement of Mr. and Mrs. Middlebrook, Indialantic, FL 219 AUTISM WHY THE INCREASED RATES? A ONE-YEAR UPDATE WEDNESDAY, APRIL 25, 2001 HOUSE OF REPRESENTATIVES, COMMITTEE ON GOVERNMENT REFORM, Washington, DC. The committee met, pursuant to notice, at 11:07 a.m., in room 2154, Rayburn House Office Building, Hon. Dan Burton (chairman of the committee) presiding. Present: Representatives Burton, Morella, Ros-Lehtinen, Horn, Davis, Weldon, Waxman, Maloney, Norton, Cummings, Kucinich, Blagojevich, Tierney, Schakowsky, and Clay. Staff present: David A. Kass, deputy counsel and parliamen- tarian; Mark Corallo, director of communications; John Callendar, counsel; S. Elizabeth Clay, Nicole Petrosino, and John Rowe, pro- fessional staff members; Robert A. Briggs, chief clerk; Robin Butler, office manager; Michael Canty and Toni Lightle, legislative assist- ants; Scott Fagan, staff assistant; Leneal Scott, computer systems manager; John Sare, deputy chief clerk;Corinne Zaccagnini, sys- tems administrator; Phil Barnett, minority chief counsel; Kate An- derson and Sarah Despres, minority counsels; Ellen Rayner, minor- ity chief clerk; and Jean Gosa, minority assistant clerk. Mr. BURTON. Good morning. A quorum being present, the Committee on Government Reform will come to order. I ask unanimous consent that all Members' and witnesses' written and opening statements be included in the record. Without objection, so ordered. I ask unanimous consent that all articles, exhibits, or extraneous or tabular material referred to beincluded in the record. Without objection, so ordered. During the
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