Table 4. Location of the various genes

Modified April 28, 2021

Originally modified from AAC 1999 43:2823-30 with permission from ASM Journals

• Gene
• Number
• Genera

METHYLASES

e

erm(A)

11

Aggregatibacter^L,1, Bacteroides, Enterococcus , Haemophilus^r, Helcococcus, Klebsiella,

• a
• a

Listeria, Peptostreptococcus , Prevotella , Staphylococcus, Streptococcus erm(B)

39

Aggregatibacter¹, Aerococcus, Bacillus, Bacteroides^a, Campylobacter^af,

a

Citrobacter, Corynebacterium, Clostridium , Clostridioides, Enterobacter, Escherichia,

• a
• a

Eubacterium , Enterococcus, Fusobacterium , Gallibacterium^cp, Gemella, Haemophilus, Klebsiella,

a

Lactobacillus, Listeria^cc, Micrococcus, Neisseria, Pantoea, Pediococcus, Peptostreptococcus ,

• a
• a

Porphyromonas , Proteus, Pseudomonas, Rothia, Ruminococcus , Salmonella^cn, Serratia, Shigella ^ag, Staphylococcus, Streptococcus, Ureaplasma^O, Wollinella^a, Treponema^b, Trueperella¹

a

erm(C)

38

Aeromonas^y, Aggregatibacter^L, Actinomyces, Bacillus, Bacteroides , Brevundimonas  ^y, Burkholderia ^y, Campylobacter, Capnocytophaga^a,ca ,Chryseomonas^y, ,Corynebacterium,

• n
• a

Clostridium^a,n Escherichia ,   Eubacterium ,   Enterococcus, Fusobacterium^a,br, Haemophilus^r, Lactobacillus, Listeria, Macrococcus, Micrococcus, Neisseria, Paenibacillus^y, Pasteurella ^y,

• a
• a

Prevotella , Peptostreptococcus , Pseudomonas^y, Pseudoramibacter^a,br, Rhizobium^y, Salmonella, Serratia, Sinorhizobium^y, Sphingomonas^y, Stenotrophomans^y, Staphylococcus, Streptococcus,

a

Trueperella ⁿ, Wolinella erm(D)

27

Bacillus, Salmonella

• a
• a
• a
• a
• n

• erm(E)
• Bacteroides , Eubacterium , Fusobacterium , Ruminococcus , Saccharopolyspora , Shigella,

Streptomyces

a

erm(F)

30

Aggregatibacter ^L, Actinomyces, Bacteroides , Campylocater, Capnocytophaga^a,ca

• a
• a
• a

Clostridium , Corynebacterium, Eubacterium , Enterococcus, Escherichia, Fusobacterium ,

• a
• a

Gardnerella, Haemophilus^r, Lactobacillus, Mobiluncus , Neisseria, Peptostreptococcus ,

• a
• a
• a

Porphyromonas , Prevotella , Pyramidobacter ^ci, Riemerella^am, Ruminococcus , Salmonella,

• a
• b
• a
• a

Shigella, Selenomonas , Staphylococcus, Streptococcus, Treponema , Veillonella , Wolinella

• a
• a
• a

erm(G)

9

Bacillus, Bacteroides , Catenibacterium , Clostridioides ^a,by , Listeria, Lactobacillus, Prevotella ,

a

Porphyromonas , Staphylococcus erm(H) erm(I)

1111

Streptomyces Streptomyces Streptomyces Streptomyces erm(N) erm(O)

a

erm(Q)

6

Aggregatibacter ^L, Bacteroides , Clostridioides ^a,by , Staphylococcus, Streptococcus

a

Wolinella erm(R) erm(S) erm(T)

219

Arthrobacter, Aeromicrobiumⁿ Streptomyces Enterococcus, Escherichia, Erysipelothrix^aj, Haemophilus^ai, Lactobacillus, Listeria, Streptococcus, Salmonella, Staphylococcus^m erm(U)

1

Streptomyces

• a
• a

erm(V)

11

Brevundimonas^y, Chryseomonas^y, Eubacterium , Fusobacterium , Leifsonia^y, Mesorhizobium^y, Paenibacillus^y, Pseudomonas^y, Rhizobium^y, Shewanella^y, Streptomyces erm(W)

1

Micromonospora erm(X)

28

Abiotrophia^ci , Actinotignum (Actinobaculum)^ae, Actinobacillus^bp, Actinomyces^ci, Alloprevotella^ci

Bifidobacterium^a, Burkholderia^y, Brevundimonas^y, Capnocytophaga^ci ,Corynebacterium^ci,

Cutibacterium^{a, bp}(Propionibacterium). Eubacterium^ci , Granulicatella^ci, Klebsiella^ci , Lautropia^ci , Leifsonia^y, Leptotrichia^ci , Mobiluncus^cj ,Neisseria^ci , Paenibacillus^y, Pseudomonas^y, Rhizobium^y,

Shewanella ^y, Sphingomonas^y, Stenotrophomanas , Streptococcus^ci , Trueperella (Arcanobacterium),

Veillonella ^ci

erm(Y) erm(Z)

1111111

Staphylococcus Streptomyces Streptomyces Streptomyces Streptomyces Staphylococcus Bacillus erm(30) erm(31) erm(32) erm(33) erm(34)

a

erm(35) erm(36) erm(37) erm(38)

1111

Bacteroides Micrococcus Mycobacterium Mycobacterium erm(39) erm(40) erm(41)^bi erm(42)

1118

Mycobacterium Mycobacterium Mycobacterium Escherichia, Enterobacter, Klebsiella, Mannheimia, Morganella, Pasteurella, Photobacterium, Salmonella erm(43) erm(44) erm(44)_v erm(45) erm(46) erm(47) erm(48)^as

1111211

Staphylococcus Staphylococcus Staphylococcus Staphylococcus Rhodococcus, Listeria Helcococcus Staphylococcus

erm(49)^bd erm(50)^br

erm(51)^bw

erm(52)^cf erm(53)^cm

111

11

Bifidobacterium^a Cutibacterium^a (Propionibacterium)^bp Rhodococcus

Clostridioides Campylobacter

q

S-ADENYOSYLMETHIONINE rRNA METHYLASES PhLOPS_A

cfr

14

Bacillus, Citrobacter, Clostridioides^by, Enterococcus, Escherichia^ab, Jeotgalicoccus^z, Listeria, Klebsiella, Macrococcus^z, Proteus^x, Providencia, Salmonella, Staphylococcus, Streptococcus^az

cfr(B)^ak cfr(C)^at cfr(D)^bh

4

41

Bacillus^at, Clostridioides^a,by, Enterococcus, Paenibacillus^bz Campylobacter, Clostridioides^a,by, Clostridium^a, Klebsiella Enterococcus cfr(E)^bu

1

Clostridioides^a,by

ATP-F PROTEIN RIBOSOMAL PROTECTION^bj

lsa(A) lsa(B) lsa(C) lsa(D)^bv lsa(E)

4121

5

Clostridioides^a. Clostridium^a , Enterococcus, Listeria Staphylococcus Gardnerella, Streptococcus^p Lactococcus Enterococcus, Erysipelothrix^aq , Listeria^cc, Staphylococcus , Streptococcus^av

aa

lsa(E)_v

2

Stenotrophomonas, Ureaplasma^O msr(A)

17

Bacteroides^av, Brevundimonas^y, Burkholderia^y, Chryseomonas^y Corynebacterium, Enterobacter, Enterococcus, Gemella, Listeria, Lysinibacillus^y, Photobacterium^y, Pseudomonas, Shewanella^y, Staphylococcus, Streptococcus, Streptomyces^y, Ureaplasma^O msr(C)

1

Enterococcus

c

msr(D)

26

Acinetobacter, Bacteroides^a,d , Citrobacter, Clostridioides^a,by, Corynebacterium, Enterococcus,

a

Enterobacter, Escherichia, Erysipelothrix^bb, Gemella, Fusobacterium , Haemophilus , Klebsiella, Listeria, Morganella, Morococcus^ci , Neisseria, Proteus, Providencia, Pseudomonas, Ralstonia, Salmonella, Staphylococcus, Streptococcus, Serratia, Ureaplasma^o

s,bj

msr(E)

11

Acinetobacter, Citrobacter, Escherichia, Gallibacterium^cp, Klebsiella, Mannheimia^ck, Morganella, Pasteurella, Pseudomonas^bq ,Salmonella, Serratia

msr(F)^bx msr(G)^cd msr(H)^bx

msr(I)^ce

2

2

1

1

Macrococcus, Staphylococcus

Macrococcus, Staphylococcus

Macrococcus

Streptococcus

vga(A)

5

11

Leifsonia^y, Listeria, Paenibacillus^y, Salmonella^cl , Staphylococcus vga(A)_LC vga(A)_v
Staphylococcus Staphylococcus

vga(B)

21111231

Enterococcus, Staphylococcus Staphylococcus

k

vga(C) vga(D)^t vga(E)^v vga(F) ^ce optrA^ax poxtA^cb eat(A)_v
Enterococcus Staphylococcus Streptococcus Enterococcus, Staphylococcus Enterococcus, Pediococcus, Staphylococcus Enterococcus sal(A)^ar

111

Staphylococcus Streptomyces Bacillus varM vlmR^bm

ATP-F Protein [Mechanism not tested]^bk

car(A)

1

Streptomyces lmr(C) ole(B) ole(C) srm(B) tlr(C)

11111

Streptomyces Streptomyces Streptomyces Streptomyces Streptomyces

MAJOR FACILITATORS [Efflux]

lmr(A)

1

Streptomyces^bc mef(A)

32

Acinetobacter, Bacteroides^a, Citrobacter, Clostridioides^{a, by}, Corynebacterium,

a

Enterococcus, Enterobacter, Escherichia, Erysipelothrix^bb, Fusobacterium , Gemella, Haemophilus^r Klebsiella, Lactobacillus, Listeria, Micrococcus, Morganella, Neisseria, Pantoea, Pediococcus^ad, Providencia, Proteus, Ralstonia, Rothia^j, Pseudomonas, Salmonella, Serratia, Staphylococcus, Listeria, Streptococcus, Stenotrophomonas, Weissella^ad mef(B)

3

52211

Escherichia, Klebsiella, Salmonella

Citrobacter^cg, Pseudoalteromonas^cg, Photobacterium, Shewanella^cg, Vibrio

Macrococcus, Staphylococcus^cd

Macrococcus, Staphylococcus

mef(C) mef(D)^bx

mef(F)^cd

mef(H)^cf mef(J)^ch
Clostridioides Streptococcus

ESTERASES

ere(A)

16
9

Achromobacter, Aermonas, Citrobacter, Enterobacter, Escherichia, Klebsiella, Laribacter, Morganella, Pantoeae, Providencia, Pseudomonas, Salmonella, Serratia, Staphylococcus, Stenotrophomonas, Vibrio

• ere(B)
• Acinetobacter, Citrobacter, Enterobacter, Escherichia, Klebsiella, Morganella, Proteus,

Pseudomonas, Staphylococcus

ere(C) ere(D)^ba

33

Escherichia, Klebsiella, Riemerella Elizabethkingia, Riemerella, Salmonella

LYASES

vgb(A)

21

Enterococcus, Staphylococcus

• vgb(B)
• Staphylococcus

TRANSFERASES

a

lnu(A)

67

Staphylococcus, Bacteroides^av , Clostridium , Listeria, Lactobacillus^g, Pediococcus^ad

a

lnu(B)
Clostridium , Enterococcus, Erysipelothrix^aq, Listeria^cc, Staphylococcus, Streptococcus^h, Virgibacillus lnu(C)

91

Brachyspira^bd,be ,Campylobacter, Streptococcus, Haemophilus^L, Bifidobacterium^bf, Cloacibacillus^a,bf Enterococcus^bf, Megaspaera^bf , Veillonella^bf

• lnu(D)
• Streptococcus

lnu(E)

29

Enterococcus, Streptococcus

• lnu(F)
• Aeromonas, Comamonas, Desulfobacterium, Escherichia, Leclercia, Morganella, Proteus,

Providencia, Salmonella lnu(G)^ao lnu(H)^ay lnu(P)^ap vat(A) vat(B) vat(C) vat(D) vat(E)

2111212311

Enterococcus, Virgibacillus Riemerella Clostridium Staphylococcus Enterococcus, Staphylococcus Staphylococcus Clostridium^a, Enterococcus Bacteroides^aw, Enterococcus, Lactobacillus

• Yersinia
• vat(F)

• vat(G)^t
• Enterococcus