Introduction and service overview

elliottyoung.co.uk >

About us

 Formed in 2004 by Dan Elliott and Tim Davies. Prior to this, they worked together at Loewy Group where they both serviced several conference/ events clients.  Collective expertise in planning, creating and implementing effective marketing communications strategies for a variety of small to large event and conference brands.  Has grown by reputation, and has built a solid core team of events marketing and communications enthusiasts.  Our mission is to become the UK’s most trusted facilitator of design and digital communications services for events and conferences.

What we do

Branding. Digital. Marcomms.

Brand workshops and Site design and build All printed or PDF guidelines Open Source technologies collateral Corporate identity and Content Management Marketing campaigns visual language Systems Advertising Brand propositions HTML and dynamic emails Direct mail Vision, values and SEO Personalised messaging behaviours Social media Point of sale Our clients The core account team

Dan Elliott Tim Davies Ben Barrows Assim Heetun Creative Director Account Director Design and Digital Executive Graphic Designer

Dan has more than 18 years of experience in After completing an MSc in Marketing Ben is the company wizz-kid. He was spotted as an Assim has worked with our team for the past two creating clear, compelling B2B communications to ideal member of the elliottyoung team after being years and is very familiar with all of the current professional markets such as pharmaceutical and straight into the agency sector and began noticed by talent scouts. In his spare time Ben events and conference brands that elliottyoung corporate events. producing hugely successful strategic marketing occupies himself by building computers and currently services. self-learning 3D CAD architecture design, all of the He is ultimately responsible for developing visual Adobe Packages (he also teaches these in local With a passion for all things creative, Assim’s communications for all of elliottyoung’s clients and Tim’s strengths lie in close project management colleges), WordPress, CSS/HTML and jQuery. It experience spans producing illustrations for Tesco ensures that all creative is on-brand, on-message, and strategic thinking. His ability to add value to goes without saying, he also rides a motorbike. (creating engaging brand labels for their own on-time and on-budget. clients through his strategy recommendations, version of Pimms), MTV (animation), Hydra advice and pro-active input is very well known by Ben works with both the design and digital teams (illustrating characters for their rulebook), a series Dan graduated from the London College of elliottyoung’s clients. and in a variety of roles. He has in-depth knowledge Communications attaining distinctions and a of the systems used by clients and is always on hand children’s toy shops and accompanying comics, and degree in Graphic Design and Communications. Coupled with his friendly manner, his ability to for support and advice. His enthusiasm for all things illustrations for a variety of social gaming brands. deliver even highly complex, multi-channel related to on-and-offline communications means He is highly skilled across the entire marketing mix international campaigns that elliottyoung’s clients don’t just feel like they’re Assim’s passion and dedication to producing and has expertise in creating highly effective solus to budget and deadline is highly regarded by in safe hands, they also benefit from working with compelling designs has been crucial to design projects through to full, through-the-line, clients and colleagues alike. someone who loves solving problems and making elliottyoung’s growth in recent years. integrated marketing campaigns that play out improvements. across advertising, direct marketing, literature, Tim works closely with clients on a multitude of display/POS and digital platforms. projects – ranging from very fast, tactical, small budget projects right through to devising and leading multi-layered marketing strategies. How we normally work:

Research Presentation Refinement Sign off Production Follow up and explore of options

We take the brief We create a number of We analyse all feedback Final feedback Our artwork team Project postmortems and research issues that design approaches to to refine the options progresses the creative prepares deliverables help refine our own it has raised. hit the right tone of down to a chosen to sign off stage. for print. This involves processes, providing us We may well check voice and message. approach. This is We always ensure ‘flight checking’, with essential feedback competitor approaches Successful design presented back to the written sign off before ensuring correct print to continually improve or current thinking always involves client for further production and insist on set up, or web- the way we work with in design and feedback and refinement or approval. supplying electronic optimised output files if clients from day to day. marketing. refinement. copy records. appropriate. Our experience

We’ve marketed over 500 events and conferences for international and domestic sectors for the past decade. Here’s a list of some of the event brands we’ve serviced. For each of these clients we’ve undertaken part or whole of the entire campaign implementation, from branding through to brochures, DM, web banners, email templates, websites, etc...

Aerospace Testing (Reed Exhibitions) Inspex (Reed Exhibitions) Offshore Europe (Reed Exhibitions) Aircraft Interiors (Reed Exhibitions) Intelligent Energy (Reed Exhibitions) Online Information (Incisive Media) Arabian Travel Market (Reed Travel International Golf Travel Market (Reed Travel Packaging Innovation (Reed Exhibitions) Exhibitions) Exhibitions) PPMA (Reed Exhibitions) Caffe Culture (Upper Street Events)  International Luxury Travel Market (Reed Resource (UBM) Travel Exhibitions) City Break (Reed Exhibitions) Storage Expo (Reed Exhibitions) Interplas (Reed Exhibitions) Corrugated (Reed Exhibitions) The CIPD’s Annual Conference (The Chartered Documation (Reed Exhibitions) ITEC (Reed Exhibitions) Institute of Personnel and Development) EuroFinance (The Economist) Library Information Show (Incisive Media) The IDM’s B2B Marketing and Data Summit Food ingredients (UBM) Mediterranean Travel Fair (Reed Travel (The IDM) Exhibitions) IFE (Fresh Montgomery) The IDMF (Reed Exhibitions) National Incentive Show (Reed Exhibitions) IGTM (Reed Travel Exhibitions) Total Packaging (Reed Exhibitions) Nepcon (Reed Exhibitions) ISTM (Reed Travel Exhibitions) UUVS (Reed Exhibitions) Oceanology International (Reed Exhibitions) in-cosmetics Asia (Reed Exhibitions) Project management

Many of our clients enjoy using Basecamp, the world’s best known and easy-to-use project management tool.

It’s easier than using email since all correspondence, feedback, assets and design versions regarding a particular project are captured within each ‘job folder’ within Basecamp. It’s proven to be so useful that for all new clients we now insist on using the service as a matter of course (at no extra cost to you of course). It makes email searches and ‘sorry, I didn’t see that instruction’ a thing of the past. Portfolio

We have created marketing campaigns for over 500 events and conferences and our digital product, Event Engine, has been the website platform of choice for over 1,000 national and international events. Portfolio: Elements 2016

Brand for launch exhibition for furniture suppliers

Elements, a new exhibition for furniture suppliers which covers components, fixtures & fittings, decors and finishings, will take place alongside W16, the leading UK exhibition for woodwork machinery from 2-5 October 2016 at the NEC in Birmingham. VISITOR TARGET: 6,000 Case study: VISITOR ACTUAL: 11,607 Brand and campaign for UBM Lead Partner:

launch event, Resource. 3–5 March 2015 ExCeL, London Manufacture Retailer

CAMPAIGN OVERVIEW Design User

In the summer of 2013 we were contacted by the Recycling Re-use/Repair Sector Resource team after an opportunity arose for UBM Farming Consumer to create this new event. The timeframe window was Biological way tighter than usual and within a few short weeks Restoration extraction

Anaerobic from UBM being made aware of the opportunity, Biogas digestion the show had to be conceptualised, branded and launched. Having worked with elliottyoung for over Circular Economy in construction – vision for the future four years, Rosie Geyman, International Marketing RESOURCE 2015 HAS A SPECIAL SECTOR FOCUS ON RESOURCE EFFICIENT CONSTRUCTION AND HOW THE Manager at UBM knew that we were the agency to PRINCIPLES OF THE CIRCULAR ECONOMY CAN BE APPLIED Register now for your IN THE BUILT ENVIRONMENT. SESSIONS INCLUDE: free place at ask to come up with the show brand. In her words: REUSING ‘WASTE’ OR LEGACY STRUCTURES IN NEW BUILDINGS www.resource-event.com RESOURCE EFFICIENT MATERIALS AND PRODUCTS – MAKING THE RIGHT CHOICES DEMOUNTABLE CONSTRUCTION AND MATERIALS RECOVERY AUDITING AND TRACKING WASTE TO REDUCE COSTS We met the team, they listened to the show’s pitch, AND IMPROVE SUSTAINABILITY USING WASTE TO POWER BUILDINGS OFF GRID asked questions, and digested the information. Then DESIGNING BUILDINGS ACCORDING TO THE PRINCIPLES OF THE CIRCULAR ECONOMY they got to work. The campaign they developed was purposefully very flexible, not reliant on one particular image or message. We knew the industry was rapidly changing with new messages evolving with regularity. So, a suite of related imagery was created, using a Their creative is always on the money. variety of simple shapes and a vibrant colour palette. Even though they were given just one week to come up with the campaign, they nailed it first go. Rosie Geyman, International Marketing Manager, Ecobuild & Resource

Resource 2016:

REGISTER TODAY AT: REGISTER TODAY AT: REGISTER TODAY AT: G www.resource-event.com G www.resource-event.com G www.resource-event.com

Good leaders Proving circular think business models circular

Guiding your business to resource efficiency

Lead Partner Lead Partner Lead Partner AUTOMOTIVE CHEMICALS CONSTRUCTION AUTOMOTIVE CHEMICALS CONSTRUCTION AUTOMOTIVE CHEMICALS CONSTRUCTION

ELECTRONICS FOOD RETAIL TEXTILES ELECTRONICS FOOD RETAIL TEXTILES ELECTRONICS FOOD RETAIL TEXTILES

Resource 2016 is the free to attend, three day conference-led exhibitor Resource 2016 is the free to attend, three day conference-led exhibitor Resource 2016 is the free to attend, three day conference-led exhibitor that helps businesses take steps towards resource efficiency and the circular that helps businesses take steps towards resource efficiency and the circular that helps businesses take steps towards resource efficiency and the circular economy. The event is totally cross industry, bringing together expert economy. The event is totally cross industry, bringing together expert economy. The event is totally cross industry, bringing together expert enablers with practitioners to find solutions across the complete supply chain. enablers with practitioners to find solutions across the complete supply chain. enablers with practitioners to find solutions across the complete supply chain.

www.resource-event.com www.resource-event.com www.resource-event.com Portfolio: Arabian Travel Market

Our 10th year of brand and

2014 2013 2014 2013 AUDITED EVENT نادي املشرتين واملتحدثون 4,230 5,014 املساحة املحجوزة “أمتار مربعة” 22,827 24,549 جهات اعالمية 788 800 األجنحة الرئيسية 383 402 مهنيون - سفر وسياحة 16,078 17,822 الرشكاء العارضون 2,347 2,343 مجموع الحضور 21,096 23,636 مجموع الرشكات العارضة campaign 2,745 2,730 with top Reed Exhibitions event

The Arabian Travel Market, held 23,600 $2.1bn 2,745 Route visitors from 131 countries of new business exhibiting companies in Dubai in May, is the Middle generated at ATM 2014 Planner

East’s annual flagship event ATM Partners for the travel, business travel, and tourism industries. For ten years straight we have retained Register today at wwww.arabiantravelmarket.com/itb VISIT KATARA HOSPITALITY AT STAND HC6850 the contract for branding and campaign roll out. Portfolio: MIPIM Japan

2 dAYS TO NETWORK, LEARN ANd TOP 10 REASONS TO ATTENd MIPIM JAPAN, THE 1ST REAL ESTATE Brand for launch S uLTANEOu SHOWCASE PROJECTS SIM d fORuM fOR JAPANESE ANd VISITORS ENgLISH AN Through high-quality conference sessions, targeted networking events and JAPANESE TRANSLATION gLOBAL LEAdERS a sponsors’ showcase area, MIPIM Japan offers all professionals an in-depth > > > > > look into innovation and the Japanese property market. of Japan’s1 2 largest3 4 5 During 2 days of expert-led conferences and high-level transactional Gain up-to-date Discover the latest Stay at the cutting Connect with key Generate new leads networking, MIPIM Japan offers the ideal setting to initiate in and outbound market insight from property investment edge of real estate decision-makers from for future business investment and create business opportunities. leading industry opportunities and innovation all property sectors NETWORK WITH THE ONLINE dATABASE OPENINg experts trends in Japan through dedicated COCKTAIL: events and online property eventtools 2,000 JAPANESE ANd gLOBAL PARTICIPANTS SPONSORS Japanese real estate International stakeholders Property and finance professionals share their source capital or new professionals gather projects and their unrivalled opportunities in Japan from all asset classes – > > > > > know-how with the world office, retail, infrastructure, Schedule meetings Search the list of Contact participants Network with 6 7 8 9 10 leisure, residential before and during the attending companies participants in an Gain visibility and Showcase your Identify potential Increase brand Promote your on-site forum. Available online informal setting recognition for your projects and solutions partners and exposure among key presence with tailor- ST and on your mobile 2 dAYS TO NETWORK, LEARN ANd TOP 10 REASONS TO ATTENd MIPIM JAPAN, THE 1 REAL ESTATE phone real estate projects to leading market investment sources international investors made solutions to stakeholders and property leaders meet your businessuLTANEO uS SHOWCASE PROJECTS SIM d fORuM fOR JAPANESE ANd VISITORS objectives ENgLISH AN Through high-quality conference sessions, targeted networking events and JAPANESE TRANSLATION gLOBAL LEAdERS a sponsors’ showcase area, MIPIM Japan offers all professionals an in-depth > > > > > 20 CONfERENCE SESSIONS look into innovation and the Japanese property market. 1 2 3 4 5 During 2 days of expert-led conferences and high-level transactional Gain up-to-date Discover the latest Stay at the cutting Connect with key Generate new leads networking, MIPIM Japan offers the ideal setting to initiate in and outbound market insight from property investment edge of real estate decision-makers from for future business investment and create business opportunities. OPENINg leading industry opportunities and innovation all property sectors 3 KEYNOTES: 8 EXPERT PANELS: 2 WORKSHOPS:NETWORK WITH THE ONLINE dATABASESPONSORS: BOOKexperts YO uRtrends PACKA in Japan gE through dedicated COCKTAIL: eventsVEN and online uE tools Get inspired by Benefit from market Share and learn NOW fROM ¥800,000 / 2,000 JAPANESE ANd gLOBAL PARTICIPANTS thought leaders leaders’ expertise from your peers SPONSORS Japanese real estate International stakeholders Property and finance 3 professionals share their source capital or new professionals gather EuR 5,850 * projects and their unrivalled opportunities in Japan from all asset classes – > > > > > know-how with the world office, retail, infrastructure, Schedule meetings Search the list of Contact participants Network with 6 7 8 9 10 leisure, residential before and during the attending companies participants in an Gain visibility and Showcase your Identify potential Increase brand Promote your on-site forum. Available online informal setting recognition for your projects and solutions partners and exposure among key presence with tailor- and on your mobile CONTACT uS fOR MORE INfORMATION phone real estate projects to leading market investment sources international investors made solutions to stakeholders and property leaders meet your business 2 MASTERMINdS: 2 THEMATIC 2 NETWORKINg Japan: Lily Ono, gIMLI International: Luigia De Ianni, Reed MIdEM The Prince Parkobjectives Tower is located in the 20 CONfERENCE SESSIONS [email protected] [email protected] heart of Tokyo, close to the city’s landmark Discover top CEOs’ visions BREAKfASTS: LuNCHES: +81 3 6264 0193 +33 1 79 71 9635 Tokyo Tower and within easy reach of two for the future of the 3 KEYNOTES: 8 EXPERT PANELS: 2 WORKSHOPS: SPONSORS: BOOK YOuR PACKAgE differentVENuE subway lines, the Toei Oedo Line Wake up your mind through CultivateGet inspired relationships by withBenefit from market Share and learn NOW fROM ¥800,000 / and Toei Mita Line. industry thought leaders leaders’ expertise from your peers active exchange clients & colleagues EuR 5,8503* Standing amidst a verdant park, with Tokyo VISITORS: BOOK EARLYCONTACT AN uS fORd MORE SAVE INfORMATION Tower visible off to one side, the Prince 2 MASTERMINdS: 2 THEMATIC 2 NETWORKINg Japan: Lily Ono, gIMLI International: Luigia De Ianni, Reed MIdEM ThePark Prince Tower Park Tower offers is located a in widethe variety of facilities [email protected] [email protected] heartfrom of Tokyo, bowling close to the and city’s landmarkbeauty treatments, to JaPan: TIME TO TAKE A CLOSER LOOK Discover top CEOs’ visions BREAKfASTS: UntilLu FridayNCHES: 19/03/2015 +81 3 6264 0193 ¥70 000+33 1 79 71 96352512* Tokyo Tower and within easy reach of two differentspas, subway fitness lines, the and Toei Oedo hot Line springs. for the future of the Wake up your mind through Cultivate relationships with and Toei Mita Line. industry active exchange Untilclients Sunday & colleagues 10/05/2015 ¥90 000 2649* Japan boasts one of the most New building development is Political and economic indicators 1,000 M² SPONSORS’ SHOWCASE AREA Standing amidst a verdant park, with Tokyo 20-21 MAY 2015 VISITORS: BOOK EARLY ANd SAVE Tower visible off to one side, the Prince robust and resilient real estate driven by innovative architecture, 2 Park Tower offers a wide variety of facilities THE PRINCE PARK TOWER HOTEL, TOKYO, JAPAN are reflecting the increasing From Monday 11/05/2015 ¥125 000 901* MIPIMfrom bowling Japan and beauty is treatments, organised to by Reed MIDEM JaPan: TIME TO TAKE A CLOSER LOOK Until Friday 19/03/2015 ¥70 000 2512* markets, and investment is sustainable & connected cities, number of opportunities to build to highlight and discover the most impressive property projects and solutions on spas, fitness and hot springs. 1,000 M² SPONSORS’ SHOWCASE AREA Until Sunday 10/05/2015 ¥90 000 2649* 20-21 MAY 2015 Japan boasts one of the most New building development is Political and economic indicators skyrocketing with a growth of as well as state-of-the-art business in and with Japan. THE PRINCE PARK TOWER HOTEL, TOKYO, JAPAN robust and resilient real estate driven by innovative architecture, are reflecting the increasing From Monday 11/05/2015 ¥125 000 2901* MIPIM Japan is organised by Reed MIDEM the Japanese market to highlight and discover the most impressive propertygO projects TO WWW and solutions.MIPIMJAPAN on .COM TO REgISTER markets, and investment is sustainable & connected cities, number of opportunities to build 38% in 2013. technological & sustainable skyrocketing with a growth of as well as state-of-the-art business in and with Japan. the Japanese market gO TO WWW.MIPIMJAPAN.COM TO REgISTER WWW.MIPIMJAPAN.JP WWW.MIPIMJAPAN38% in 2013. .COMtechnological & sustainable

310,000, 662 003 557 RCS NANTERRE, having registered offices located at 27-33 Quai Alphonse Le Gallo – 92100 BOULOGNE BILLANCOURT (France), VAT number FR91 662 003 557 VAT (France), Alphonse Le Gallo – 92100 BOULOGNE BILLANCOURT offices located at 27-33 Quai registered having 662 003 557 RCS NANTERRE, (SAS) with a capital of 2 310,000, a joint stock company MIDEM, Reed by MIPIM® is organised forests well-managed / 40% from fibres 60% recycled : Paper reserved. All rights MIDEM. of Reed trademark MIPIM® is a registered conception. WWW.MIPIMJAPAN.JP WWW.MIPIMJAPAN.COM

310,000, 662 003 557 RCS NANTERRE, having registered offices located at 27-33 Quai Alphonse Le Gallo – 92100 BOULOGNE BILLANCOURT (France), VAT number FR91 662 003 557 VAT (France), Alphonse Le Gallo – 92100 BOULOGNE BILLANCOURT offices located at 27-33 Quai registered having 662 003 557 RCS NANTERRE, (SAS) with a capital of 2 310,000, a joint stock company MIDEM, Reed by MIPIM® is organised forests well-managed / 40% from fibres 60% recycled : Paper reserved. All rights MIDEM. of Reed trademark MIPIM® is a registered conception. *Prices in Euro are converted values for your information - all billing will occur in Japanese Yen Crédit photo Image&Co – Media channel co *Prices in Euro are converted values for your information - all billing will occur in Japanese Yen Crédit photo Image&Co – Media channel co

Portfolio: WTM Portfolio WTM Portfolio In the last 12 months“ the portfolio generated US $7 billion “in business deals WTM Portfolio – World Travel Market 55,029 Why Exhibit? 2013 overall attendance www.wtmlondon.com World Travel Market 2-5 November 2015, Excel, London, UK Africa $3.7 billion World Travel Market, the leading global event for the travel industry, is a must-attend four day of new business World Travel Market business-to-business event. It attracts the world’s leading travel industry executives who negotiate generated at WTM 2013 Latin America contracts and discover the latest research, insight and opinion. More than 50,000 senior industry executives attend every year to negotiate business deals worth more than $3.7 billion and attend Arabian Travel Market more than 100 educational seminars. 95% of WTM exhibitors met Key Show Features good quality contacts World Travel Market 96% Contacts of exhibitors said they were satisfied with WTM 2013

WTM 2013 Visitor Areas of Interest WTM 2013 Visitor Numbers 11,908 meeting requests were made through MY WTM (online diary Portfolio networking tool) 1% WTM 1% 50,000 attendees 2% In the last 12 months the portfolio generated in business deals 1% £3.9 billion 1% 3% 3% 8,544 4% Buyers Club attendees 32% 7% 40% 2,888 8% 30,664 Media 60%

10% 698 15% Main Stand Holders 11% 4,205 Stand Sharers

www.wtmworld.com Organised by: NEXT PAGE SAVE PRINT The WTM Portfolio creates personal and business opportunity through its leading world travel events & industry networks with global reach and regional focus, providing our customers with quality Organised by: contacts, content and communities.

® 2 - 3 May 2014 • Cape Town www.wtmworld.com

22 - 24 April 2015 São Paulo @ATM www.wtmworld.com 5–6 May 2015

Meet high calibre luxury travel 25 decision-makers buyers in high value 1-2-1 specifically focused on meetings buying luxury travel

In association with International Luxury www.wtmworld.com Travel Market, Arabian Travel Market 2015 will feature an exclusive luxury programme The crème de la crème of ‘ILTM@ATM’. Middle East luxury travel luxury travel buyers brought buyers and the best in luxury travel providers to take part in pre-scheduled directly to your stand at ATM appointments over two days.

Over 50 suppliers and buyers will meet and develop business relationships at the leading global B2B event for the Middle Up to 25 pre-scheduled International Luxury East inbound and outbound travel industry. meetings with Middle East Host Hotel luxury travel buyers

arabiantravelmarket.com/luxury Organised by: Travel Market PANTONE 485 Portfolio: event property UK’s largest launch of Brand for their marketing collateral. We branded itandcreated and conference took place. 2014 the inaugural UK expo property industry event. In the world’s largest annual Held in Cannes,MIPIMis MIPIM UK THE UK BUILDING do business. projects andopportunities investors tomeet,discuss UK playersandinternational provides amarketplacefor for property professionals. It exhibition andconference MIPIM UKistheUK’s largest [email protected] +44 (0)2075280086oremail For more information pleasecall 60+ CONFERENCES 60+ CONFERENCES 2,000 4,000 PARTICIPANTS M 2 EXHIBITIONAREA www.mipimuk.co.uk

MIPIM is a registered trademark of Reed MIDEM – All rights reserved Portfolio: British Pavillion

Brand and website for launch events company

We branded this UK- based events company that aims that to take the best of British organisations into the heart of international trade markets. Portfolio: Homegrown Live

Brand and website for launch event Portfolio: HansonWade Branding a top 100 fastest- growing company

We created the logo, brand id, website, and collateral templates for this Sunday Times Fast Track 100 conference and events company. Portfolio: HansonWade

Apply & Translate Whole Genome & Exome Sequencing into Clinical Utility

December 3rd-4th 2014, San Diego, CA

Excellent, high yield “conference. Boston Children’s Hospital 25-27 February 2015 | Boston, USA It exceeded my “expectations. The talks were high quality Unlocking Precision Genome Editing for and the interaction among participants Therapeutic Development & Biomedical was excellent. I thought that conference was well Research Applications Genentech “ organized, sessions were well planned and we had a good mix of This is academic & pharma designed to speakers. So overall, describe the conference was a profound great success. impact CRISPR GSK is having on basic research KEITH JOUNG Harvard University and therapeutic www.cges-summit.com RESEARCHED & DEVELOPED BY: development. It Tel: +1 212 537 5898 | Email: [email protected] ALEXANDRA GLUCKSMANN RODGER NOVAK will explore the Editas Medicine CRISPR Therapeutics research tools, bioinformatics and expertise needed to make the most of this breakthrough technology Eric Rhodes on 2nd AnnuAl Book BEforE CRISPR Congress 2015 12Th dEcEmBEr and savE up To £500 ERIC RHODES Horizon Discovery

GEORGE CHURCH Harvard University

LEAD PARTNER HOSTING PARTNER PROGRAM PARTNERS EXHIBITOR

27th – 29th January 2015, London, UK

Taking actionable steps on the Big data Journey to revolutionise value-Based crispr-congress.com RESEARCHED & DEVELOPED BY: personalised healthcare Tel: +1 212 531 5898 | Email: [email protected]

Big DiP was “a huge success for everyone who attended. The participants were top notch. I learned

a lot and made don coWling some good contacts. Proteus Digital Health The content was kingslEy manning extremely strong davidE cErvEllin eBay HSCIC overall. marc Berger, Vice President, real World Data & analytics, Pfizer on Big DiP USa 2014

mEl WalkEr Otsuka Pharmaceutical Europe

Programme Partner Panel Partner John QuackEnBush Dana-Farber Cancer Institute

www.bigdatapharma-europe.com RESEARCHED & DEVELOPED BY: Tel: +44 (0) 203 141 8700 | Email: [email protected] Portfolio: HansonWade

Immune Checkpoint Inhibitors 2015 Big Data in Healthcare April 28–30 2015 Boston, MA March 24th-26th | Boston, MA In partnership with:

September 8th-11th 2015 BOSTON, MA In the future... INSIGHTS ON ADC 3 marketed drugs. Another 25+ in clinical CHARACTERIZATION development for a variety of oncology indications. According to the Drug OPDIVO KEYTRUDA YERVOY Pipeline Update (2014) 64% % % % there are 109 immune 29 28 75 checkpoint drugs in What are the most useful characterization methods? of respondents believe of respondents think of respondents think of respondents think that IMMUNE CHECKPOINT FACTS How robust do you feel your characterization BIG DATA IN HEALTHCARE that all drugs will be that drug developers will companion diagnostics development. strategies are? that building the right paired with a companion co-develop companion will change the face of 1st BENCHMARKING SURVEY diagnostic diagnostics in house patient care and the Mass spectrometry infrastructure will aid healthcare system as we 69% of respondents thought their in big data adoption currently know it 2014 saw two more approvals for PD-1 2nd Cancer immunotherapy market inhibitors, Bristol-Myers Squibb’s Chromatographic lot-release characterization set to be worth $9 billion by 2022 *. Opdivo and Merck’s Keytruda. was good or great Immune checkpoint inhibitors will rd 15% In 2013 world wide 3 Immunoassays ONLY 33% dominate with 85% market share. sales of Yervoy were 28% $9 BN BY 2022 The next decade will see an $960 million. th of respondents have * Characterization of early IHC PCR annual growth rate of 24.1% . 4 Spectroscopic already implemented What is the *Source: PharmaTimes and PR Newswire stage conjugation was rated as FISH NGS a big data strategy THE TOP 3 BIG DATA predominant type Bristol-Myers Squibb’s Yervoy, a CTLA4 targeting 5th Electrophoretic of CDx assay you antibody, was approved by the FDA in 2011 and average to poor by 57% Microarrays Yervoy impacted treatment European Union as second line treatment for INITIATIVES TO BE are using? approaches for unresectable or metastatic melanoma in 2012. 21% metastatic malignant melanoma. Data from 1,861 patients in clinical Characterization of process INVESTED IN ARE: When are catabolites/ metabolites first identified 31% trials showed 3-year and 7-year development was rated average overall survival of 22% and 17%, during ADC development? 5% Bristol-Myers Squibb are the respectively*. Currently, what is the most exciting opportunity for CDx development? leading player with 7+ immune or above by 88% *Source: Nature Reviews Drug Discovery checkpoint modulators in 100% of those surveyed 6% clinical development. Other Clinical of respondents are not even 1 34% Liquid biopsies pharmaceutical giants include considering a big data strategy Opdivo has been granted Promising Incorporating biomarkers Merck, AstraZeneca and 31% Innovative Medicine status by the 95% into clinical trial design Genentech. Preclinical 2 MHRA. It is the only PD-1 immune 17% NGS checkpoint inhibitor with this status. 3 Results from two Phase III clinical 65% Integration Early development 15% Multiplex diagnostics studies demonstrated its superiority Partnerships are central to the of data markets current and growth Exploring emerging and favourable safety profile ¼ of participants said they were sources 3% disease areas compared to chemotherapy*. trajectory. A key aim is clinical trial Development collaborations to evaluate immune 30% Late discovery “likely” or “very likely” 50% of sophisticated checkpoint modulators. 2014 alone Conducting of respondents have analytics 6% to outsource ADC analytical data predictive Selecting the right partner saw over 12 such collaborations chosen the right between biotech and pharma. collection during development analysis Immune checkpoint inhibitors may technology to aid your 9% 16% help treat brain cancers. Novel Data mining and storage Regulatory approval big data adoption research shows primary and Where is there the biggest need for new analytical secondary brain cancers often characterization techniques? exhibit high expression of PDL1. The Currently, what IMMUNE CHECKPOINTTwo clinically validated FACTS is the biggest study included 117 patients with ADA levels CHECKPOINT targets are CTLA-4 and 15% challenge for glioblastoma and 116 patients with 37% * PD-1/PD-L1. In addition, Aggregates How would you like to learn about new companion 32% brain metastases . PATHWAYS 39% CLOSELY FOLLOWED BY: Aligning drug-CDx diagnostics? Reimbursement promising novel targets characterization methods? Biotransformation metabolites co-development *Source: ScienceDaily in preclinical and early 45% clinical developments DAR are TIM3, LAG3 and 29% VISTA and co-stimulatory Drug product impurities pathways such as OX40 35% 18% What phase of drug development are you What type of circulating biomarker Free drug-linker species and CD137. of respondents are using Oracle currently most predominantly operating in? are you currently exploring most? 32% Site of conjugation as their database management 53% Discovery (Source: Pardoll, 2012) 26% 35% Unconjugated 83% 45% 63% 53% 24% solution 14% 10% Circulating tumor DNA mAb 15% Publication White paper Presentation Webinar Internal discussion 21% Phase I/II 33% Nucleic acids COMBINATION THERAPIES 20% Pre-Clinical 22% Immune checkpoint modulation combinations will be the cornerstone to future development. 2014 saw prolific combination agreements, Relative abundance of each Sample stability Conjugation site/chemistry Phase III leaving very little on the table for late comers. species THE BIGGEST CHALLENGE THAT IS EMERGING 17% CTCs The biochemical, Peptide mapping & Robustness & Formulation & Regulatory approval/ WITHIN BIG DATA IMPLEMENTATION IS THE 16% Post-approval 10% physicochemical conjugation site interference from dosage form miRNAs 01: 02: 03: 04: properties of the ADCs serum What disease area do you predominantly operate in? Mode of action of conjugated Which types of information need to be Assay consistency with OTHER IMMUNOTHERAPIES – TRADITIONAL CANCER IMMUNE CHECKPOINT OTHER – ADCS, drug delivered to the DMPK? statistical significance CAR T-CELL THERAPY, CANCER TREATMENT – CHEMOTHERAPY, IMMUNE BOOSTERS MODULATORS VACCINES RADIOGRAPHY Popular Responses 78% 7% 7% 4% 3% Efficient & robust Sequence DAR (inc DAR 0 Binding activity assay sample handling information of content & free ELISA method & * THE IMPACT OF BIG DATA IN HEALTHCARE procedures the mAb drug) related protocols Oncology Immunology CNS Cardiovascular Paediatric/ IMMUNE CHECKPOINT INHIBITORS IN THE PIPELINE Pre-natal Target of the mAb & LC/MS method & sample Likely break-down products DRUG (ALTERNATIVE NAME) COMPANY TARGET FIRST INDICATION DEVELOPMENT STATUS availability of target & preparation (catabolites or degradents) specific ADA Opdivo (nivolumab) Bristol-Myers Squibb PD1 Malignant melanoma Marketed (Japan) & impurities (that might On a scale of 1-10, how invested is your have different t1/2) On a scale of 1-10, how important are companion Keytruda (pembrolizumab) Merck & Co. PD1 Malignant melanoma Marketed (USA) organization in companion diagnostics? diagnostics to the future of precision medicine? MEDI4736 AstraZeneca PDL1 NSCLC Phase III 9.0 6.8 MPDL3280A Roche/Genentech PDL1 Urothelial bladder cancer or NSCLC Phase III Tremelimumab AstraZeneca CTLA4 Mesothelioma Phase II 3% Pidilizumab (CT-011) CureTech PD1 Haematologic or solid tumours Phase II Rating average Rating average Lirilumab (BMS-986015) Bristol-Myers Squibb KIR Haematologic or solid tumours Phase II 18% 21% Indoximod (NLG-9189) NewLink Genetics IDO1 Breast cancer Phase II Most Interesting Takeaway from the World CDx Survey 2015: INCB024360 Incyte IDO1 Solid tumours Phase II MEDI0680 (AMP-514) AstraZeneca PD1 Solid tumours Phase I LIMS systems There is a revealing discrepancy between the In order to progress, we need to identify: MSB-0010718C Merck KGaA PDL1 Solid tumours Phase I importance of companion diagnostics for the 1. What is preventing further investment Custom reporting pipelines How is PF-05082566 Pfizer 4-1BB (also known as CD137) Haematologic or solid tumours Phase I future development of precision medicines and and application of companion diagnostic characterization the level of investment currently taking place MEDI6469 AstraZeneca OX40 (also known as CD134) Solid tumours Phase I strategies? Generic reports data best shared BE THE GAME FUTURE OF within pharma, biotech and academia. 2. What needs to happen to stimulate further BMS-986016 Bristol-Myers Squibb LAG3 Haematologic or solid tumours Phase I investment? NLG-919 NewLink Genetics IDO1 Solid tumours Phase I Raw data internally? 3. How can drug developers capture the value of Urelumab (BMS-663513) Bristol-Myers Squibb 4-1BB (also known as CD137) Haematologic or solid tumours Phase I CHANGER HEALTHCARE CDx in the future? Other 4-IBB, tumour necrosis factor receptor superfamily member 9; CTLA4, cytotoxic T-lymphocyte protein 4; IDO1, indoleamine 2,3-dioxygenase 1; LAG3, lymphocyte activation gene 3 protein; KIR, 27% The CDx Community will come together in September at the 6th World CDx Summit in Boston killer cell immunoglobulin-like receptor; NSCLC, non-small-cell lung cancer; OX40, tumour necrosis factor receptor superfamily member 4; PD1, programmed cell-death protein 1; PDL1, programmed cell-death ligand 1. to answer these questions and more to accelerate the co-development of targeted therapies and tailored diagnostics. Join this multi-stakeholder CDx community to define the critical roadmap for *Source: Adapted from Webster, Nature Reviews Drug Discovery 13, 883–884 (2014) 31% target identification to simultaneous launch of drug-CDx combinations. Tel: +1 212 537 5898 Email: [email protected] bigdata-healthcare.com @BigDataHealth1 Big Data in Healthcare Tel: + 1 212 531 5898 Email:[email protected] www.world-cdx.com RESEARCHED & Tel: +1 212 537 5898 Email: [email protected] www.worldadc-usa.com DEVELOPED BY: www.immune-checkpoint.com Immune Checkpoint Inhibitors Tel: +1 212 537 5898 | Email: [email protected] @WorldCDx Companion Diagnostics @world_adc #WorldADC Antibody Drug Conjugates Portfolio:

International Golf Travel Market

www.igtm.co.uk

The Premier event for the golf travel industry

Magma Arte & Congresos, Tenerife

Organised by: Portfolio: The Collection

International luxury brand launch, website and campaign

The Collection is one of the world’s most prestigious consumer events, held in Abu Dhabi. We created the brand, website and all sales/marketing collateral for the inaugural campaign.

Portfolio: Beyond the froth

Online community for the coffee industry

An online smörgåsbord of industry and product news, supplier directory, featured suppliers, and social conversation - entirely CMSified. Easy to manage, easy to use, and created for the UK’s largest coffee industry community. Portfolio: GovNet

Since 2010 we’ve been servicing GovNet Communications, producing event branding, conference brochures and other associated collateral, their conference websites, and their flagship magazine, moderngov. Portfolio: London Wild Bird Watch

Brand, website and web app for launch exhibition

London Wild Bird Watch is the annual event for bird and wildlife enthusiasts, amateurs and professionals alike. We created the brand, website, web app, and all marketing collateral for the launch event. Thank you

Dan Elliott: 0845 054 0070 [email protected]

elliottyoung.co.uk >