<<

A B C Spliceosomal . are divided into categories according to their best known function. Official name, original gene name, and full official names are listed.. Yellow shading indicates well-known canonical splicing factors. 1 2 Official Name Original Name Full Official Name 3 4 CAP Binding Proteins 5 NCBP1 CBP80 Nuclear Cap Binding Subunit 1, 80 kDa 6 NCBP2 CBP20 Nuclear Cap Binding Protein Subunit 2, 20 kDa 7 RNMT RG7MT1 RNA (guanine-7-) methyltransferase 8 9 U1 snRNP Components and Associated Proteins 10 ARGLU1 ARGLU1 And Glutamate Rich 1 11 DDX5 p68 DEAD-Box 5 12 DHX9 RHA DExH-Box Helicase 9 13 EWSR1 EWS EWS RNA Binding Protein 1 14 FUS hnRNP P2 FUS RNA Binding Protein 15 LUC7L pLUC7L LUC7 Like 16 LUC7L3 LUC7A LUC7-like 3 17 PRPF40A FBP-11 Pre-MRNA Processing Factor 40 Homolog A 18 PRPF4B PRP4 Kinase Pre-MRNA Processing Factor 4B 19 RBM25 fSAP49 RNA binding motif protein 25; promotes U1 binding to 5' splice site 20 SNRNP70 U170K Small Nuclear Ribonucleoprotein 70 kDa 21 SNRPA U1A Small Nuclear Ribonucleoprotein Polypeptide A 22 SNRPC U1C Small Nuclear Ribonucleoprotein Polypeptide C 23 TIA1 TIA1 TIA1 Cytotoxic Granule-Associated RNA Binding Protein 24 TIAL1 TIAR TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 25 26 SR Proteins 27 SRSF1 ASF, SF2 Serine/Arginine-rich Splicing Factor 1 28 SRSF11 p54, NET2 Serine/Arginine-rich Splicing Factor 11 29 SRSF2 SC35 Serine/Arginine-rich Splicing Factor 2 30 SRSF3 SRP20 Serine/Arginine-rich Splicing Factor 3 31 SRSF4 SRP75 Serine/Arginine-rich Splicing Factor 4 32 SRSF5 SRP40 Serine/Arginine-rich Splicing Factor 5 33 SRSF6 SRP55 Serine/Arginine-rich Splicing Factor 6 34 SRSF7 9G8 Serine/Arginine-rich Splicing Factor 7 35 SRSF9 SRp30c Serine/Arginine-rich Splicing Factor 9 A B C 36 TRA2A TRA-2 Alpha Transformer 2 alpha homolog (Drosophila) 37 TRA2B TRA-2 Beta Transformer 2 beta homolog (Drosophila) 38 39 3' Splice-site and Branchpoint Binding Proteins 40 PUF60 PUF60 Poly-U binding splicing factor 60KDa 41 SF1 BBP Splicing factor 1 42 U2AF1 U2AF35 U2 small nuclear RNA auxiliary factor 1 43 U2AF2 U2AF65 U2 small nuclear RNA auxiliary factor 2 44 45 U2 snRNP Components 46 DDX46 hPRP5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 47 HTATSF1 TAT-SF1 HIV-1 Tat specific factor 1 48 PHF5A SF3B14b PHD finger protein 5A 49 SF3A1 SAP114 Splicing Factor 3A, Subunit 1 50 SF3A2 SAP62 Splicing Factor 3A, Subunit 2 51 SF3A3 SAP61 Splicing Factor 3A, Subunit 3 52 SF3B1 SAP155 Splicing Factor 3B, Subunit 1 53 SF3B2 SAP145 Splicing Factor 3B, Subunit 2 54 SF3B3 SAP130 Splicing Factor 3B, Subunit 3 55 SF3B4 SAP49 Splicing Factor 3B, Subunit 4 56 SF3B5 SF3b10 Splicing Factor 3b Subunit 5 57 SF3B6 SF3B14a Splicing Factor 3b Subunit 6 58 SNRPA1 U2A' Small Nuclear Ribonucleoprotein Polypeptide A' 59 SNRPB2 U2B" Small Nuclear Ribonucleoprotein Polypeptide B2 60 U2SURP fSAPa U2 snRNP-associated SURP domain containing 61 62 U4, U5, U6 Components 63 CD2BP2 U5-52 CD2 (cytoplasmic tail) binding protein 2 64 DDX23 U5-100 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 65 EFTUD2 U5-116 Elongation Factor Tu GTP Binding Domain Containing 2 66 PPIH PPIH Peptidylprolyl isomerase H (cyclophilin H) 67 PRPF3 hPRP3 Pre-mRNA processing factor 3 68 PRPF31 hPRP31 Pre-mRNA processing factor 31 69 PRPF4 hPRP4 Pre-mRNA processing factor 4 70 PRPF6 U5-102 Pre-mRNA processing factor 6 71 PRPF8 Pre-mRNA prcessing factor 8 72 SART1 SNU66 SART1, U4/U6.U5 Tri-SnRNP-Associated Protein 1 A B C 73 SART3 U6 snRNP-binding proteinSquamous Carcinoma Antigen Recognized By T Cells 3 74 SNRNP200 U2-200 Small Nuclear Ribonucleoprotein U5 Subunit 200 75 SNRNP40 U5-40 Small Nuclear Ribonucleoprotein U5 Subunit 40 76 SNU13 hSNU13 Small Nuclear Ribonucleoprotein 13 77 TXNL4A U5-15 Thioredoxin Like 4A 78 USP39 SAD1 Ubiquitin Specific Peptidase 39 79 80 PRP19 Complex Proteins 81 AQR Aquarius Aquarius -Binding Spliceosomal Factor 82 CDC5L CDC5L Cell division cycle 5-like 83 CRNKL1 hCRN Crooked neck pre-mRNA splicing factor 1 84 PRPF19 hPRP19 Pre-mRNA processing factor 19 85 XAB2 SYF1 XPA Binding Protein 2 86 87 Sm Core Proteins 88 SNRPB SmB/B' Small Nuclear Ribonucleotide Polypeptides B and B1 89 SNRPD1 SmD1 Small Nuclear Ribonucleoprotein D1 Polypeptide 16 kDa 90 SNRPD2 SmD2 Small Nuclear Ribonucleoprotein D2 Polypeptide 16.5 kDa 91 SNRPD3 SmD3 Small Nuclear Ribonucleoprotein D3 Polypeptide 18 kDa 92 SNRPE SmE Small Nuclear Ribonucleoprotein Polypeptide E 93 SNRPF SmF Small Nuclear Ribonucleoprotein Polypeptide F 94 SNRPG SmG Small Nuclear Ribonucleoprotein Polypeptide G 95 LSM1 hLSm1 LSM1 Homolog, U6 snRNA and mRNA Degradation Associated 96 LSM2 hLSm2 LSM2 Homolog, U6 snRNA and mRNA Degradation Associated 97 LSM3 hLSm3 LSM3 Homolog, U6 snRNA and mRNA Degradation Associated 98 LSM4 hLSm4 LSM4 Homolog, U6 snRNA and mRNA Degradation Associated 99 LSM6 hLSm6 LSM6 Homolog, U6 snRNA and mRNA Degradation Associated 100 LSM7 hLsm7 LSM7 Homolog, U6 snRNA and mRNA Degradation Associated 101 SNRPN SNRPN Small Nuclear Ribonucleoprotein Polypeptide N 102 103 Catalytic Step II Factors 104 CDC40 hPRP17 Cell division cycle 40 105 DHX15 hPRP43 DEAH (Asp-Glu-Ala-His) box helicase 15 106 DHX38 hPRP16 DEAH (Asp-Glu-Ala-His) box polypeptide 38 107 DHX8 hPRP22 DEAH (Asp-Glu-Ala-His) box polypeptide 8 108 PRPF18 hPRP18 Pre-mRNA processing factor 18 109 SLU7 hSLU7 SLU7 Homolog, Splicing Factor A B C 110 111 Cyclophilin-like Proteins 112 PPIE Cyclophilin-33 Peptidylprolyl Isomerase Like 3 113 PPIL1 CYPL1 Peptidylprolyl Isomerase Like 1 114 PPIL2 Cyclophilin-60 Peptidylprolyl Isomerase Like 2 115 PPIL3 Cyclophilin J Peptidylprolyl Isomerase Like 3 116 117 Junction Complex Proteins 118 ACIN1 Acinus Apoptotic condensation inducer 1 119 CWC22 fSAPb CWC22 spliceosome-associated protein 120 EIF4A3 eIF4A3 Eukaryotic translation initiation factor 4A3 121 MAGOH Magoh Mago-nashi homolog, proliferation-associated 122 PYM1 WIBG PYM Homolog 1, Exon Junction Complex Associated Factor 123 RBM8A Y14 RNA binding motif protein 8A 124 RNPS1 RNPS1 RNA binding protein S1, serine-rich domain 125 SRRM1 SRm160 Serine And Arginine Repetitive Matrix 1 126 127 HnRNP Proteins 128 HNRNPA1 hnRNP A1 Heterogeneous nuclear ribonucleoprotein A1 129 HNRNPA2B1 hnRNPA2B1 Heterogeneous nuclear ribonucleoprotein A2B1 130 HNRNPC hnRNP C Heterogeneous nuclear ribonucleoprotein C (C1/C2) 131 HNRNPD hnRNP D Heterogeneous nuclear ribonucleoprotein D 132 HNRNPDL hnRNPDL Heterogeneous Nuclear Ribonucleoprotein D Like 133 HNRNPF hnRNP F Heterogeneous nuclear ribonucleoprotein F 134 HNRNPH1 hnRNPH1 Heterogeneous nuclear ribonucleoprotein H1 (H) 135 HNRNPH2 hnRNPH2 Heterogeneous nuclear ribonucleoprotein H2 136 HNRNPK hnRNP K Heterogeneous nuclear ribonucleoprotein K 137 HNRNPL hnRNP L Heterogeneous nuclear ribonucleoprotein L 138 HNRNPM hnRNP M Heterogeneous nuclear ribonucleoprotein M 139 HNRNPR hnRNP R Heterogeneous nuclear ribonucleoprotein R 140 HNRNPU hnRNP U Heterogeneous nuclear ribonucleoprotein U (SAFA) 141 PTBP1 hnRNP I binding protein 1 142 RALY RALY RALY heterogeneous nuclear ribonucleoprotein 143 144 Non-snRNP Spliceosomal Proteins 145 BCAS2 SPF27 Breast carcinoma amplified sequence 2 146 BUB3 hBUB3 BUB3 mitotic checkpoint protein A B C 147 BUD13 fSAP71 BUD13 homolog (S. cerevisiae) 148 BUD31 BUD31 BUD31 homolog (S. cerevisiae) 149 CACTIN CACTIN Cactin, spliceosome C complex subunit 150 CDK12 CRKRS Cyclin-dependent kinase 12 151 CFAP20 fSAP23 Cilia and flagella associated protein 20 152 CIRBP CIRP Cold inducible RNA binding protein 153 CTNNBL1 NAP Catenin, beta like 1 154 DDX17 p72 DEAD-Box Helicase 17 155 DDX3X DDX3 DEAD-Box Helicase 3, X-Linked 156 DDX41 Abstract DEAD-Box Helicase 41 157 DHX16 hPRP2 DEAH-Box Helicase 16 158 DNAJC8 SPF31 DnaJ (Hsp40) homolog, subfamily C, member 8 159 ELAVL1 HUR ELAV like RNA binding protein 1 160 ENO1 MBP1 Enolase 1 161 ESS2 DGCR14 DiGeorge syndrome critical region gene 14 162 FUBP3 FBP3 Far upstream element (FUSE) binding protein 3 163 GTF2I GTFII-I General Factor IIi 164 IK PRP4 Kinase IK cytokine, down-regulator of HLA II 165 ILF2 nFAT-45 Interleukin enhancer binding factor 2 166 ILF3 nFAT-90 Interleukin enhancer binding factor 3 167 KHDRBS1 Sam68 KH RNA Binding Domain Containing, Signal Transduction Associated 1 168 MATR3 MATRIN3 Matrin 3 169 MFAP1 MFAP1 Microfibrillar-associated protein 1 170 MOV10 FSAP113 Mov10 RISC Complex RNA Helicase 171 NONO p54 Non-POU Domain Containing Octamer Binding 172 PAXBP1 fSAP105 PAX3 and PAX7 binding protein 1 173 PLRG1 PRP46 Pleiotropic regulator 1 174 PPM1G Pp2Cgamma Protein phosphatase, Mg2+/Mn2+ dependent, 1G 175 PRPF38A PRPF38A Pre-MRNA Processing Factor 38A 176 PTH2 TIP39 Parathyroid Hormone 2 177 RBM4 Lark Homolog RNA Binding Motif Protein 4 178 RBM15 OTT RNA binding motif protein 15 179 RBM17 SPF45 RNA binding motif protein 17 180 RBM22 fSAP47 RNA binding motif protein 22 181 RBM39 CAPER RNA binding motif protein 39 182 SERBP1 PAI1 RNA-Binding Protein SERPINE11 MRNA Binding Protein 1 183 SFPQ PSF Splicing Factor Proline And Glutamine Rich A B C 184 SMU1 fSAP57 Smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 185 SPHKAP SKIP SPHK1 interactor, AKAP domain containing 186 SRRM2 SRm300 Serine/arginine repetitive matrix 2 187 SYF2 fSAP29 SYF2 pre-mRNA-splicing factor 188 TCERG1 CA150 Transcription elongation regulator 1 189 TRIR fSAP18 RNA Component Interacting Rnase 190 WDR77 Methylosome Protein 50 WD Repeat Domain 77 191 WBP11 WBP11 WW domain binding protein 11 192 WTAP WTAP Wilms tumor 1 associated protein 193 XRN2 5'-3' Exoribonuclease 2 5'-3' Exoribonuclease 2 194 YBX3 DBPA Y box binding protein 3 195 ZNF207 fSAPc protein 207 196 197 3' end Formation Proteins 198 PABPC1 PABP1 Poly(A) binding protein, cytoplasmic 1 199 CPSF6 CF-I-68kD Cleavage and specific factor 6 200 CPSF7 CPSF7 Cleavage And Polyadenylation Specific Factor 7 201 NUDT21 CFI-25kD Nudix Hydrolase 21 202 PABPN1 PABPN Poly(A) binding protein, nuclear 1 203 204 Heat Shock Proteins 205 DNAJA1 Heat Shock 40 KDa ProteinDnaJ 4 Heat Shock Protein Family (Hsp40) Member A1 206 HSPA2 HSP70 Heat Shock Protein Family A (Hsp70) Member 2 207 HSPA5 GRP78 Heat Shock Protein Family A (Hsp70) Member 5 208 HSPA8 HSP71 Heat Shock Protein Family A (Hsp70) Member 8 209 210 SMN Complex Proteins 211 SMN1 SMN 1, telomeric 212 DDX20 Gemin3 DEAD-Box Helicase 20 213 GEMIN2 Gemin2 Gem Nuclear Associated Protein 2 214 GEMIN4 Gemin4 Gem Nuclear Organelle Associated Protein 4 215 GEMIN5 Gemin5 Gem Nuclear Organelle Associated Protein 5 216 GEMIN6 Gemin6 Gem Nuclear Organelle Associated Protein 6 217 SMNDC1 SPF30 Survival Motor Neuron Domain Containing 1 218 STRAP UNRIP Serine/Threonine Kinase Associated Protein 219 SYNCRIP HNRNPQ Synaptotagmin Binding Cytoplasmic RNA Interacting Protein 220 A B C 221 RNAP II Subunits 222 POLR2A POLR2A Polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 223 POLR2B POLR2B Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 224 POLR2C POLR2C Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 225 POLR2D POLR2D Polymerase (RNA) II (DNA directed) polypeptide D, 16kDa 226 POLR2E POLR2E Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 227 POLR2G POLR2G Polymerase (RNA) II (DNA directed) polypeptide G, 19kDa 228 POLR2H POLR2H Polymerase (RNA) II (DNA directed) polypeptide H, 17.1 kDa 229 POLR2J POLR2J Polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 230 POLR2J2 POLR2J2 RNA Polymerase II Subunit J2 231 232 TREX Complex Proteins 233 THOC1 HPR1 THO complex 1 234 THOC2 THO2 THO complex 2 235 THOC5 FSAP79 THO complex 5 236 THOC3 TEX1 THO complex 3 237 THOC6 fSAP35 THO complex 6 238 THOC7 fSAP24 THO complex 7 239 DDX39B UAP56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 240 ALYREF ALY/REF Aly/REF export factor 241 CHTOP SRAG Chromatin target of PRMT1 242 DDX39A UAP56 homolog DExD-Box Helicase 39A 243 ERH ERH Enhancer of rudimentary homolog (Drosophila) 244 NCBP3 ELG Nuclear Cap Binding Subunit 3 245 POLDIP3 SKAR Polymerase (DNA-directed), delta interacting protein 3 246 SARNP CIP29 SAP domain containing ribonucleoprotein 247 SRRT ARS2 Serrate, RNA effector molecule 248 ZC3H11A ZC3H11A Zinc Finger CCCH-Type Containing 11A 249 250 RNA Binding Proteins Not in Other Categories 251 ADAR ADAR deaminase, RNA-specific 252 CAPRIN1 GPIAP1 Cell cycle associated protein 1 253 CCNT1 Cyclin T1 Cyclin T1 254 CCNT2 Cyclin T2 Cyclin T2 255 G3BP2 G3BP-2 GTPase activating protein (SH3 domain) binding protein 2 256 LARP1 LARP La ribonucleoprotein domain family, member 1 257 LARP7 LARP7 La ribonucleoprotein domain family, member 7 A B C 258 MEPCE MEPCE Methylphosphate capping 259 NPM1 NPM Nucleophosmin (nucleolar phosphoprotein B23, numatrin) 260 PNN Pinin, desmosome associated protein 261 RBP3 IRBP Retinol binding protein 3, interstitial 262 RBM7 RBM7 RNA binding motif protein 7 263 SRP14 ALURBP Signal recognition particle 14kDa 264 STRBP HEL162 Spermatid perinuclear RNA binding protein 265 TUT1 U6-TUTase Terminal uridylyl transferase 1, U6 snRNA-specific 266 ZCCHC8 ZCCHC8 Zinc finger, CCHC domain containing 8 267 ZFR HZFR Zinc finger RNA binding protein 268 269 Proteins 270 EXOSC4 EAP1 Exosome component 7 271 EXOSC7 RRP41 Exosome component 4 272 MTREX MTR4 Mtr4 Exosome RNA Helicase 273 274 Transcription-related Proteins 275 ABCA4 ABCA4 ATP Binding Cassette Subfamily A Member 4 276 ACTL6A BAF53A SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin 277 ARID1A BAF250 AT rich interactive domain 1A (SWI-like) 278 ARID2 ARID2 AT rich interactive domain 2 (ARID, RFX-like) 279 ASH2L ASH21 ASH2 Like Histone Lysine Methyltransferase Complex Subunit 280 BCL7C B-Cell CLL/Lymphoma 7CBCL Tumor Suppressor 7C 281 CCDC6 TPC Coiled-coil domain containing 6 282 CDK9 CDK9 Cyclin-dependent kinase 9 283 CHD4 CHD-4 Chromodomain helicase DNA binding protein 4 284 DPY30 DPY30 Dpy-30, Histone Methyltransferase Complex Regulatory Subunit 285 GTF2B TF2B General IIB 286 H1FX H1X H1 histone family, member X 287 H2AFV H2A.Z-2 H2A histone family, member V 288 HCFC1 HCF-1 Host cell factor C1 289 HEXIM1 Hexim Hexamethylene Bisacetamide Inducible 1 290 JunB AP-1 Jun B proto-oncogene 291 KMT2D MLL4 Lysine Methyltransferase 2D 292 LDB1 NLI LIM domain binding 1 293 NCOA6 RAP250 coactivator 6 294 PBRM1 PBRM1 Polybromo 1 A B C 295 PDRG1 PDRG And DNA Damage Regulated 1 296 PFDN6 HKE2 Prefoldin subunit 6 297 RPAP3 NOP17 RNA polymerase II associated protein 3 298 RUVBL1 TIP49 RuvB-like AAA ATPase 1 299 SAFB SAF-B Scaffold attachment factor B 300 SAFB2 SAF-B2 Scaffold attachment factor B2 301 SAP18 SAP18 Sin3A-associated protein, 18kDa 302 SET IPP2A2 SET nuclear proto-oncogene 303 SIX4 AREC3 SIX 4 304 SMARCA4 BAF190 SWI/SNF related, matrix associated, actin dependent regulator of chromatin 305 SMARCC1 BAF155 SWI/SNF related, matrix associated, actin dependent regulator of chromatin 306 SMARCC2 BAF170 SWI/SNF related, matrix associated, actin dependent regulatorof chromatin 307 SMARCD1 BAF60A SWI/SNF related, matrix associated, actin dependent regulatorof chromatin 308 SMARCE1 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin 309 SPEN SHARP Spen Family Transcriptional Repressor 310 SUPT5H SPT5 SPT5 Homolog, DSIF Elongation Factor Subunit 311 SUPT6H SPT6 SPT6 Homolog, Histone 312 TAF15 TAF2N TAF15 RNA polymerase II, TATA box binding protein 313 TFAP2C ERF1 Transcription factor AP-2 gamma 314 TRIM28 KAP1 Tripartite Motif Containing 28 315 UXT ART-27 Ubiquitously Expressed Prefoldin Like Chaperone 316 WDHD1 WDHD1 WD repeat and HMG-box DNA binding protein 1 317 YAP1 COB1 Yes-associated protein 1 318 YBX1 YBX1 Y box binding protein 1 319 ZBTB21 ZBTB21 Zinc finger and BTB domain containing 21 320 ZBTB7A TIP21 Zinc finger and BTB domain containing 7A 321 ZMYND8 RACK7 Zinc finger, MYND-type containing 8 322 323 Miscellaneous 324 ABCF3 ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 325 AHNAK2 AHNAK2 AHNAK 2 326 AKAP8 AKAP 95 A kinase (PRKA) anchor protein 8 327 BOD1L1 FAM44A Biorientation of in cell division 1-like 1 328 CAPZA1 CAPPA1 Capping protein (actin filament) muscle Z-line, alpha 1 329 CAPZB CAPB Capping protein (actin filament) muscle Z-line, beta 330 CCBL2 KAT3 Cysteine conjugate-beta lyase 2 331 CSNK2A2 CK2A2 Casein kinase 2, alpha prime polypeptide A B C 332 CSNK2B CKIIbeta Casein Kinase 2 Beta 333 DICER1 Dicer Dicer 1, ribonuclease type III 334 DNMT1 DNMT1 DNA (cytosine-5-)-methyltransferase 1 335 GOPC PIST Golgi-associated PDZ and coiled-coil motif containing 336 GORAB GO Golgin, RAB6-interacting 337 GPATCH8 GPATCH8 G-Patch Domain Containing 8 338 KPNA2 Importin Subunit Alpha-2 Karyopherin Subunit Alpha 2 339 KCTD15 KCTD15 Potassium Channel Tetramerization Domain Containing 15 340 MKI67 MIB-1 Marker of proliferation Ki-67 341 MPRIP M-RIP Myosin phosphatase Rho interacting protein 342 PALMD PALML Palmdelphin 343 PIH1D1 NOP17 PIH1 Domain Containing 1 344 PPFIBP1 SGT2 PPFIA Binding Protein 1 345 PRRC2A PRRC2A Proline-rich coiled-coil 2A 346 PRRC2B BAT2L Proline-rich coiled-coil 2B 347 PRRC2C BAT2D1 Proline-rich coiled-coil 2C 348 PRKDC DNAPK Protein Kinase, DNA-Activated, Catalytic Polypeptide 349 SBNO1 MOP3 Strawberry notch homolog 1 350 SCYL2 SCYL2 SCY1-like 2 (S. cerevisiae) 351 SEC16A SEC16L SEC16 homolog A (S. cerevisiae) 352 UBR5 UBR5 Ubiquitin Protein Ligase E3 Component N-Recognin 5 353 WDR92 PFD6 WD Repeat Domain 92 354 YWHAZ HEL4 Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta 355 ZNF609 ZNF609 Zinc Finger Protein 609