bioRxiv preprint doi: https://doi.org/10.1101/098095; this version posted January 9, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Title: Fine-scale human population structure in southern Africa reflects ecogeographic boundaries Authors: Caitlin Uren1, Minju Kim2, Alicia R. Martin3,4, Dean Bobo2, Christopher R. Gignoux5, Paul D. van Helden1, Marlo Möller1, Eileen G. Hoal1,6§, Brenna M. Henn2,6§ 1 SA MRC Centre for TB Research, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, 8000 2 Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794 3 Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114 4 Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142 5 Department of Genetics, Stanford University, Stanford, CA 94305 6 Co-senior authors § Correspondence should be addressed to: Dr. Brenna Henn, Department of Ecology and Evolution, Life Sciences Building, Room 640, Stony Brook NY 11794 Phone: 631-632-1412 E-mail:
[email protected] OR Prof. Eileen Hoal, SA MRC Centre for TB Research, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medical and Health Sciences, Tygerberg Campus, Parow 7500 Phone: 021 938 9412 E-mail:
[email protected] Running title: Ancestry in southern Africa Data deposition: Data files are freely available on the Henn Lab website: http://ecoevo.stonybrook.edu/hennlab/data-software/ 1 bioRxiv preprint doi: https://doi.org/10.1101/098095; this version posted January 9, 2017.