Erratum to Upregulation of Long Noncoding RNA RAB11B-AS1 Promotes Tumor Metastasis and Predicts Poor Prognosis in Lung Cancer

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Erratum Page 1 of 7

Erratum to upregulation of long noncoding RNA RAB11B-AS1 promotes tumor metastasis and predicts poor prognosis in lung cancer

Tiegang Li1,2, Di Wu1,3, Qun Liu1,3, Dedong Wang1, Jinbin Chen1, Hongjun Zhao1, Lan Zhang4, Chenli Xie5, Wei Zhu3, Zhixu Chen6, Yifeng Zhou7, Soham Datta1, Fuman Qiu1, Lei Yang1, Jiachun Lu1

1The State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, China; 2Institute of Lung Disease, Guangzhou Chest Hospital, Guangzhou, China; 3Guangzhou Center for Disease Control and Prevention, Guangzhou, China; 4Department of Medical Genetics and Cell Biology, GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, China; 5Fifth People’s Hospital of Dongguan, Dongguan, China; 6Puning People’s Hospital, Puning, China; 7Department of Genetics, Medical College of Soochow University, Suzhou, China Correspondence to: Jiachun Lu, MD, PhD. The State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public health, Guangzhou Medical University, Xinzao Town, Panyu District, Guangzhou 511436, China. Email: [email protected].

doi: 10.21037/atm-2020-41 View this article at: http://dx.doi.org/10.21037/atm-2020-41

Erratum to: Ann Transl Med 2020;8:582

Upregulation of long noncoding RNA RAB11B-AS1 promotes tumor metastasis and predicts poor prognosis in lung cancer

In the article titled “Upregulation of long noncoding RNA RAB11B-AS1 promotes tumor metastasis and predicts poor prognosis in lung cancer” published in the Vol 8, No 9 (May 2020) of Annals Translational Medicine (1), Figure 3A and Figure 3B were wrong listed.

In the original version of the article, the transwell migration images for (A549 lncRNA Downregulation), (PC9 lncRNA Upregulation), and (PC9 up control) in Figure 3A were accidentally misplaced. The transwell invasion image for (A549 lncRNA downregulation), (A549 down control), (PC9 up control), and (PC9 down control) in Figure 3B was placed by mistake.

** ** A 200 IncRNA Upregulation Up Control IncRNA Downregulation Down Control 150 field) × 100

50 (per 100

Migratory cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected A549 cell lines

** ** 200

150 field) × 100

(per 100 50 Migratory cells number PC-9 A549 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected PC-9 cell lines

200 ** ** IncRNA Upregulation Up Control IncRNA Downregulation Down Control 150

B field) × 100

50 (per 100 Invasion cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected A549 cell lines 150 ** ** 100 field) ×

50 (per 100 Invasion cells number 0 PC-9 A549

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected PC-9 cell lines

© Annals of Translational Medicine. All rights reserved. Ann Transl Med 2020;8(21):1475 | http://dx.doi.org/10.21037/atm-2020-41 Annals of Translational Medicine, Vol 8, No 21 November 2020 Page 3 of 7

C IncRNA IncRNA IncRNA Up lncRNA Down Upregulation Up Control Downregulation Down Control 800 lncRNA Upregulation 800 IncRNA Downregulation

) Up Control )

3 * 3 Down Control 600 600 * * * * 400 400 *

200 * 200 * Tumor Volume (mm Volume Tumor (mm Volume Tumor 0 0 1 4 7 10 13 16 19 22 1 4 7 10 13 16 19 22 Time (Day) Time (Day)

IncRNA Up lncRNA Down 800 lncRNA Upregulation 800 IncRNA Downregulation Down Control

) Up Control ) 3 * 3 600 600 *

PC-9 A549 * * 400 * 400 *

200 * 200 * Tumor Volume (mm Volume Tumor (mm Volume Tumor 0 0 1 4 7 10 13 16 19 22 1 4 7 10 13 16 19 22 Time (Day) Time (Day) D PC-9 A549

lncRNA Upregulation

Up Control

Down Control

IncRNA Downregulation

These mistakes happened when we prepared images using the wrong folders. We carefully rechecked our original data and confirmed that this error happened in figure making, and did not affect the results or conclusion of the study. Therefore, Figure 3A and Figure 3B should be corrected as below:

** ** A 200 IncRNA Upregulation Up Control IncRNA Downregulation Down Control 150 field) × 100

50 (per 100

Migratory cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected A549 cell lines

** ** 200

150 field) × 100

(per 100 50 PC-9 A549 Migratory cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected PC-9 cell lines Figure 3A

** 200 ** B IncRNA Upregulation Up Control IncRNA Downregulation Down Control 150 field) × 100

50 (per 100 Invasion cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected A549 cell lines 150 ** ** 100 field) ×

50 (per 100 Invasion cells number 0 PC-9 A549

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected PC-9 cell lines Figure 3B

The corrected version of Figure 3 in whole is as below:

** ** A 200 IncRNA Upregulation Up Control IncRNA Downregulation Down Control 150 field) × 100

50 (per 100

Migratory cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected A549 cell lines

** ** 200

150 field) × 100

(per 100 50 PC-9 A549 Migratory cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected PC-9 cell lines

** 200 ** B IncRNA Upregulation Up Control IncRNA Downregulation Down Control 150 field) × 100

50 (per 100 Invasion cells number 0

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected A549 cell lines 150 ** ** 100 field) ×

50 (per 100 Invasion cells number 0 PC-9 A549

lncRNA IncRNA Up Control Down Control Upregulation Downregulation Transfected PC-9 cell lines

C IncRNA IncRNA IncRNA Up lncRNA Down Upregulation Up Control Downregulation Down Control

800 lncRNA Upregulation 800 IncRNA Downregulation

) Up Control * ) 3 3 Down Control 600 600 * * * * 400 400 *

200 * 200 * Tumor Volume (mm Volume Tumor (mm Volume Tumor 0 0 1 4 7 10 13 16 19 22 1 4 7 10 13 16 19 22 Time (Day) Time (Day) IncRNA Up lncRNA Down 800 lncRNA Upregulation 800 IncRNA Downregulation )

) Down Control 3

Up Control 3 * 600 600 * * * PC-9 A549 400 * 400 *

200 * 200 * Tumor Volume (mm Volume Tumor Tumor Volume (mm Volume Tumor 0 0 1 4 7 10 13 16 19 22 1 4 7 10 13 16 19 22 Time (Day) Time (Day)

D PC-9 A549

lncRNA Upregulation

Up Control

Down Control

IncRNA Downregulation

We have also submitted the experimental record, raw data, images and invoices of related reagents to the editorial office as proofs for this correction and a data sharing statement is provided in this Erratum. We apologize for the negligent errors and are very sorry for not being able to identify it at the submission and proofreading step and will strive to avoid similar mistakes in the future.

Footnote

Data Sharing Statement: Available at http://dx.doi.org/10.21037/atm-2020-41

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution- NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc- nd/4.0/.

References

1. Li T, Wu D, Liu Q, et al. Upregulation of long noncoding RNA RAB11B-AS1 promotes tumor metastasis and predicts poor prognosis in lung cancer. Ann Transl Med 2020;8:582.

Cite this article as: Li T, Wu D, Liu Q, Wang D, Chen J, Zhao H, Zhang L, Xie C, Zhu W, Chen Z, Zhou Y, Datta S, Qiu F, Yang L, Lu J. Erratum to upregulation of long noncoding RNA RAB11B-AS1 promotes tumor metastasis and predicts poor prognosis in lung cancer. Ann Transl Med 2020;8(21):1475. doi: 10.21037/atm-2020-41