Status and Mortality: Is There a Whitehall Effect in the United States?
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Studies of Cancer in Humans
2. Studies of Cancer in Humans 2.1 Burkitt9slymphoma 2.1.1 Clinical features and pathology 2.1.1 .1 Clinicalfeatures The jaw is the most frequently involved site and the commonest presenting feature in patients with Burkitt's lymphoma in equatorial Africa (Burkitt, 1958, 1970a) and Papua- New Guinea (ten Seldam et al., 1966; Bukitt, 1967; Magrath ef al., 1992). The tumour frequently affects multiple jaw quadrants (Figure 5). Jaw involvement is age-dependent, occurring much more frequently in young children, since it arises in close proximity to the developing molar tooth buds. In series of cases of Burkitt's lymphoma in Uganda, 70% of children under five years of age and 25% of patients over I4 had jaw invoIve- ment (Burkitt, 1970a). Very young children who do not have overt jaw tumours often have orbital involvement (Olurin & Williams, 1972; Figure 6); some of these orbital turnours may arise in the maxilla. In general, jaw involvement appears to be more frequent in regions of higher incidence, even within equatorial Africa; however, patients from, for example, highland regions in Africa, in which the annual incidence rate of Burktt's lymphoma is muck lower, are also of higher median age, and this probably accounts for the lower frequency of jaw turnours (Buxkitt & Wright, 1966; Kitinya & Lauren, 1982). It has been suggested that the frequency of jaw tumours is decreasing in some regions of equatorial Africa, with a corresponding increase in the fraction of abdominal turnours but with no clear change in the age-related incidence (Nawnah, 1984). Abdominal invo1vement is found in a little more than half of equatorial AErican patients at presentation (Burkitt & Wright, 1963; Burkitt, 1970b; Williams, 1975) and as many as 80% of patients in other countries (Magrath, 1991, 1997). -
1/11/2006 Health in an Unequal World Michael Marmot This Is a Lightly
1/11/2006 Health in an Unequal World Michael Marmot This is a lightly edited version of the (October) 2006 Harveian Oration at the Royal College of Physicians. It will be published in Clinical Medicine and the Lancet. In poor countries, tragically, people die unnecessarily. In rich countries, too, the higher death rate of those in less fortunate social positions is unnecessary. Can there be a link between these two phenomena: inequalities in health among countries and inequalities within? Surely, it might be argued, the depredations of grinding poverty – lack of food, shelter, clean water, and basic medical care or public health – that ravage the lives of the poor in developing countries are different in kind from the way that social disadvantage leads to poor health in modern Britain, for example. The diseases of the slums of Nairobi are, to be sure, different in kind from the diseases that affect the disadvantaged in east London or Harlem, and have different proximate causes. There is, however, a link. The unnecessary disease and suffering of the disadvantaged, whether in poor countries or rich, is a result of the way we organise our affairs in society. I shall argue, in this oration, that failing to meet the fundamental human need of autonomy, empowerment, or human freedom is a potent cause of ill-health. In making this case, I shall bring together two rather disparate streams of work. The first is a report of my own research endeavour. I have sought explanations for the social gradient in health, as observed in the Whitehall studies, pointing to the fundamental importance of the circumstances in which people live and work. -
Select Biographical Sketches from the Notebooks of a Law Reporter
This is a reproduction of a library book that was digitized by Google as part of an ongoing effort to preserve the information in books and make it universally accessible. https://books.google.com 600022315 V I Sir Thomas Lawrence, Pinx. S. Ayllng, Photo. anwAaii — Lois a&StMi LORD CHIEF JUSTICE, 1801. 1 1 J ► -.Li'1-'*- '" ^OOME STREET, 1867. J2./0. e SELECT BIOGRAPHICAL SKETCHES FROM THE Note- Books of a Law Reporter. WILLIAM HEATH BENNET, Esq., OF LINCOLN'S INN, BARRISTER-AT-LAW. LONDON: GEORGE ROUTLEDGE and SONS, BROADWAY, LUDGATE HILL. NEW YORK: 416, BROOME STREET. 1867. J2./0. e //i?, LONDON : PRINTED BY TIIOMAS SCOTT, WARWICK CCURT, HOLBOBN. 7° THE EIGHT HONORABLE WILLIAM HENRY, BARON LEIGH, STONELEIGH, LORD LIEUTENANT OF THE COUNTY OF WARWICK; CUSTOS BOTULORUMj TRUSTEE OF BUSBY SCHOOL, 4c. Sc. &c. Qgfcfff gfUtthtt WITH HIS LORDSHIP'S PERMISSION, F ESPECTFULLY DEDICATED, THE AUTHOR. PREFACE. The following Sketches — for they pretend to little more than the word imports — were, at the time they were penned, thrown off without any intention of seeking for literary fame as the result of their publication. I entreat my readers to bear this in remem brance. The earlier ones appeared in a legal weekly periodical at the end of last year, and were received with some favour by many of its readers. I was subsequently advised to collect them in a separate form, to re-cast, and to enlarge them, as better adapted for more general circulation and perusal. This I have now done, and have added perhaps the more attractive feature to the Essays — Photographic Portraits of the eminent men upon whose lives and talents I have thus ventured to comment. -
Obesity and Overweight in Relation to Mortality in Men with and Without Type 2 Diabetes/Impaired Glucose Tolerance the Original Whitehall Study
Cardiovascular and Metabolic Risk BRIEF REPORT Obesity and Overweight in Relation to Mortality in Men With and Without Type 2 Diabetes/Impaired Glucose Tolerance The original Whitehall Study 1 2 G. DAVID BATTY, PHD MICHAEL G. MARMOT, FRCP IGT (n ϭ 1,030) and in those with type 2 2 2 MIKA KIVIMAKI, PHD MARTIN J. SHIPLEY, MSC diabetes (n ϭ 195) was very similar. That 3 GEORGE DAVEY SMITH, MD is, there was no suggestion that the all- cause weight-mortality relation differed between the IGT (hazard ratio [HR] per n studies of apparently healthy individ- ernment employees aged 40–69 years increase in weight category 1.12 [95% CI uals, overweight and obesity, typically when examined between 1967 and 1970, 1.00–1.25]) and diabetes group (1.19 I assessed using BMI, have been consis- representing a 74% response (22). Height [0.94–1.49], P ϭ 0.64 for difference in tently associated with an increased risk of and weight were measured using stan- gradient between groups). Similar results all-cause mortality, cardiovascular dis- dard protocols, and BMI was computed were apparent when CVD was the out- ease (CVD), and select cancers (1–4). (weight [kg]/height2 [m2]) and catego- come of interest (P ϭ 0.98). Therefore, we However, extrapolating these results to rized according to current guidelines combined the IGT and type 2 diabetes individuals with type 2 diabetes is com- (23): normal weight (18.5 to Ͻ25.0), groups, an approach we have taken else- plex and perhaps inappropriate. Studies over weight (25.0–29.99), and obesity where (26). -
Overweight and Stroke in the Whitehall Study J Epidemiol Community Health: First Published As 10.1136/Jech.45.2.138 on 1 June 1991
Jrournal of Epidemiology and Community Health 1991; 45: 138-142 Overweight and stroke in the Whitehall Study J Epidemiol Community Health: first published as 10.1136/jech.45.2.138 on 1 June 1991. Downloaded from Roger Shinton, Martin Shipley, Geoffrey Rose Abstract overweight itself, adjustment for variables which Study objective-The aim was to examine are also likely mechanisms (for example, the risk of increasing overweight for death hypertension) may be misleading.6 Some doubt, from stroke. furthermore, has recently been cast on the Design-This was a prospective cohort interpretation of the results of statistical models study, in which the main outcome measure which do not reflect the biological interactions of was the mortality ratio for stroke with the risk factors under consideration.7 8 For these increasing body mass index. reasons an analysis avoiding both inappropriate Setting-Civil service departments, adjustments and statistical modelling seemed Whitehall, London. worthwhile. The study will, however, take Subjects-Participants were 17 753 men account of cigarette smoking, both because of its aged 40 to 64 years. complex relation to obesity and stroke,9 and Measurements and main results-208 because overweight and cigarette smoking are stroke deaths were recorded. Men aged 40 to particularly relevant to intervention since they 54 in the most overweight quintile of body can be easily identified without reference to mass index had a mortality ratio of 2-01 medical practitioners. (95% confidence interval 0 9 to 4'7) The straightforward analysis of risk factors in compared to the thinnest quintile. The clusters does require large case numbers. -
(Non-Insulin-Dependent) Diabetes Mellitus and Cardiovascular Disease - Putative Association Via Common Antecedents; Further Evidence from the Whitehall Study
Diabetologia (1988) 31:737-740 Diabetologia Springer-Verlag 1988 Type 2 (non-insulin-dependent) diabetes mellitus and cardiovascular disease - putative association via common antecedents; further evidence from the Whitehall Study R. J. Jarrett t and M.J. Shipley 2 1 Division of Community Health, United Medical and Dental Schools of Guy's and St. Thomas's Hospitals (Guy's Campus), and 2 Division of Medical Statistics and Epidemiology, London School of Hygiene and Tropical Medicine, U.K. Summary. Fifteen year mortality rates are reported for men creasing duration of diabetes. With adjustment for other risk participating in the Whitehall Study in 1968-70. Subjects factors, relative risks were similar in newly diagnosed and were divided into four groups - normoglycaemic (centiles previously diagnosed diabetic men. There was no significant 1-95 of the blood glucose distribution: n=17,05t), glucose linear trend of adjusted relative risks with duration of diabe- intolerant (centiles96-100: n=999), newly diagnosed dia- tes when all diabetic men were pooled and person years at betic patients (n= 56) and previously diagnosed diabetic pa- risk calculated. The lack of effect of duration upon relative tients (n= 121) treated with diet + tablets. Relative risks for risk together with other observations suggests common, pos- all causes mortality- and from coronary and cardiovascular sibly genetic, antecedents of both Type 2 (non-insulin-de- disease deaths were calculated. Age adjusted relative risks pendent) diabetes and coronary heart disease. were highest in the newly diagnosed diabetic patients and were also increased in glucose intolerant and previously di- Key words: Type 2 (non-insulin-dependent)diabetes mellitus, agnosed diabetic men (p< 0.05), but did not increase with in- diabetes duration, cardiovascular disease mortality. -
Portland Daily Press: January 19,1887
PORTLAND DAILY PRESS. PRICE THREE CENTS. ESTABLISHED JUNE 23, 1862—VOL. 24. PORTLAND, WEDNESDAY MORNING, JANUARY 19, 1887. today trom Treasurer • Report. and FOREICN. Manager MeGunnigle telegraphed County NPECIAL NOTICE'S. terms of contracts for the State and FROM WASHINGTON. ex-Commissioner Patten Congressmen of THE PORTLAND DAILY PPESS, FROM THE KENNEBEC. printing Brockton that he had a majority players COt'XTY TAX FOR 1806. for 1875-ii and 1885 and and Milliken. Brockton Published v binding the years b; Dingley who would give every day (Sundays excep' ft the The officers were elected: Jo- partially engaged, Towns. Amount. Unpaid. directing the State Treasurer to report the following and Portland a hard A meeting will 18244 PORTLAND PUBLISHING COMa <*6 of Alabama, Chas. The Recent Brutal Eviction Cases In tight. Baldwin.$ 182.44 t amount for State printing and binding seph Wheeler, president; House Thursday 043.32 at 87 The Legislature Elects a United paid Not His Tariff be held at the American Brtdgton. Kxchanoii Street. Portland, '•/fr the last four Mr. of Mr, Randall Pushing S. Hill, secretary ; A. Vanderbilt, treasurer. for the during years. Humbert, Ambrose Ireland. evening to take preliminary steps Brunswick. 1,302.71 1.662.71 DR. E. 8. Terms Donut a Year. To mall su.^ States Senator. Aroostook, who also became interested in the Bill at Present. The executive board includes Snow, 1 he organi- Capo Elizabeth. 1,0»'.16 a stock company. REED. scrlhers. Seven Dollars a Year. If S. formation of In advance. of paid had the scope of the inquiry ex- New York, chairman; Joseph Negley, be made under the char- Casco. -
Sir John Antwisel Wyons Marions Sir John Townley Wyamarus Whalley * Temp
THE ENTWISLE FAMILY – Their ancestry according to B. Grimshaw By Peter Stanford in continuation of his earlier Review of the above work. This will attempt to follow the indicated lines of descent in more detail. Part I - The Early Ancestors? A speculative chart based on the information given by Grimshaw from claimed pedigrees of other families. In an attempt to aid examination and analysis, this has been arranged by the three generations mentioned so that apparent contemporaries appear on the same line. Sir John Antwisel Wyons Marions Sir John Townley Wyamarus Whalley * temp. Wm. I of Townley temp. Wm. I (1066-1087) lord of Stanfeld lord of Whalley Thomas Entwissel Jordan = a daughter Eustas Sir Bryan Upton = Godytha = Tiburia *dau.of Sir John A. *dau.of Sir John Antwisel Elizabeth = John temp.Wm. Rufus (1087-1100) (GAP: From this point there is a gap in Grimshaw’s narrative until Robert de Entwissel of 1212. I will pick up from there in Part 2.) Locations and communications: The most obvious meeting point between these various places would be in the vicinity of Burnley, which is where Towneley is situated, on its eastern side, twelve miles from Entwistle “as the crow flies”. Horses don’t fly, but it still looks like a short enough journey for a lusty young man on horseback using cross-country tracks; or a combination of them and the Roman road which runs right through Entwistle. There is a track of prehistoric origin, since much upgraded following much the same line, and which seems to have remained in continuous use, running from Whalley to Burnley, Towneley, Mereclough, then skirting Stansfield Moor and on to Heptonstall and beyond. -
The Whitehall Studies and Health Inequalities, 1968 to C.2010 Peder Clark
CONTEMPORARY BRITISH HISTORY https://doi.org/10.1080/13619462.2020.1856082 ‘What else can you expect from class-ridden Britain?’: the Whitehall studies and health inequalities, 1968 to c.2010 Peder Clark Centre for the Social History of Health & Healthcare, University of Strathclyde, Glasgow, UK ABSTRACT KEYWORDS The Whitehall studies of British civil servants, running from 1968 Health inequalities; until the present day, are some of the most influential in twentieth Whitehall studies; class; century public health. Believing that the stratification that they stress; heart disease observed among civil servants was replicated in wider society through the class system, the Whitehall researchers argued that inequality was a powerful force in society, literally embodied by incidence of disease. But as politicians and sociologists questioned the continuing relevance of class, this article explores how these studies reflected and were in conversation with prevailing social attitudes about inequality in end-of-century Britain. Introduction In 1996, The Great Leveller, a documentary screened on Channel 4, opened with Richard Campbell, a 43-year-old fire safety inspector at the Home Office, describing his recent and sudden heart attack. ‘Until then, like most of us’, the narrator intoned, ‘he thought that his health depended mainly on diet, exercise and smoking’. Setting up the rest of the programme, which would explore epidemiological research conducted on civil servants such as Campbell, the narrator rhetorically asked ‘But is that true?’ before replying: ‘Some scientists now think it isn’t’. Campbell’s health scare was contrasted with the happy old age of another Richard; Sir Richard Way, at 83, a former permanent secretary in the Ministry of Aviation, and apparently, ‘as fit as a fiddle’. -
James Stansfeld & the Debates About the Repeal of the Contagious
ORBIT-OnlineRepository ofBirkbeckInstitutionalTheses Enabling Open Access to Birkbeck’s Research Degree output James Stansfeld & the debates about the repeal of the contagious diseases acts in Britain and British In- dia 1860s-1890s https://eprints.bbk.ac.uk/id/eprint/40061/ Version: Full Version Citation: Ramsey, Christine July (2014) James Stansfeld & the debates about the repeal of the contagious diseases acts in Britain and British India 1860s-1890s. [Thesis] (Unpublished) c 2020 The Author(s) All material available through ORBIT is protected by intellectual property law, including copy- right law. Any use made of the contents should comply with the relevant law. Deposit Guide Contact: email 1 JAMES STANSFELD & the DEBATES ABOUT THE REPEAL OF THE CONTAGIOUS DISEASES ACTS IN BRITAIN AND BRITISH INDIA, 1860s – 1890s Thesis submitted for the degree of Doctor of Philosophy at Birkbeck College, University of London Christine July Ramsey 2 3 Abstract This thesis examines the life of James Stansfeld, (1820-1898), and in particular his contribution to the political reform of the Contagious Diseases Acts (CDAs) in England and in India. Stansfeld was a Liberal MP from a Unitarian (non-conformist) background who represented his native borough of Halifax during the Gladstone era. From the early 1870s onwards, eschewing high cabinet office, Stansfeld was a major force in the Commons parliamentary debates about the CDAs and their Indian equivalent. His political strategies included the building up and sustaining of popular support for repeal whilst simultaneously supporting repeal in the political arena. The thesis maps Stansfeld’s complex and radical arguments about women’s rights, particularly those of prostitutes, and his advocacy of, and practical support for, repeal of the CDAs both in England and India. -
Whitehall Booklet
the Whitehall II study WORK STRESS AND HEALTH: the Whitehall II study Published by Public and Commercial Services Union on behalf of Council of Civil Service Unions/Cabinet Office, CCSU: 160 Falcon Road, London SW11 2LN, Tel: 020 7223 8340, Fax: 020 7223 8363, Email: [email protected] Secretary: Charles Cochrane Cabinet office: Corporate Development Division, Cabinet Office, Admiralty Arch, The Mall, London, SW1A 2WH Copyright © 2004 CCSU/Cabinet Office Editor Dr Jane E. Ferrie Contributors Dr Ruth Bell Dr Annie Britton Dr Eric Brunner Dr Tarani Chandola Dr Jane Ferrie Ms Miriam Harris Ms Jenny Head Professor Sir Michael Marmot Ms Gill Mein Dr Mai Stafford International Centre for Health and Society/Department of Epidemiology and Public Health, University College London, UK Website: www.ucl.ac.uk/WhitehallII Telephone: +44(0)207 679 5937 WORK, STRESS AND HEALTH: the Whitehall II study Contents Foreword 2 Introduction 3 The Whitehall II study 3 The Social Gradient 4 Demands and control at work 6 Social support at work 8 Effort-reward imbalance at work 10 Job insecurity 12 Organisational change 14 Health behaviour 16 Social support outside work 18 The Work-home interface 20 Retirement 22 Summary 24 Foreword Joint CCSU/Cabinet Office laypersons’ guide to the Whitehall II research People are the Civil Service’s greatest resource and biggest asset. II studies. The team has published numerous academic papers, Their health and well being is of paramount importance to civil which provide deep insights into the underlying causes of ill servants themselves, their families, employing departments, health amongst civil servants. -
Health Impact of Psychosocial Hazards at Work: an Overview
Health Impact of Psychosocial Hazards at Work: An Overview Health Impact of Psychosocial Hazards at Work: An Overview Stavroula Leka BA MSc PhD CPsychol FRSPH Aditya Jain BA(H) MSc MA FRSPH Institute of Work, Health & Organisations, University of Nottingham Design & Layout: Philippos Yiannikouris WHO Library Cataloguing-in-Publication Data Health impact of psychosocial hazards at work: an overview / Stavroula Leka, Aditya Jain 1.Occupational health. 2.Risk management. 3.Workplace. 4.Psychology, Social. 5.Stress. 6.Risk assessment. I.Leka, Stavroula. II.Jain, A. III:World Health Organization. ISBN 978 92 4 150027 2 (NLM classification: WA 400) © World Health Organization 2010 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: [email protected]). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned.