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I N T E N D E D F O R A ofofof PsychedelicsPsychedelicsPsychedelics ininin CanadaCanadaCanada 2 1 + A U D I E N C E www.instagram.com/mushroom.medic www.mmrc.care

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PPPSSSYYYCCCHHHEEEDDDEEELLLIIICCC C CCAAANNNAAADDDAAA MMMAAAGGGAAAZZZIIINNNEEE CONTENTSCONTENTSCONTENTS 10 EDITORIAL 13 MIND BENDING EDITORIAL - 6 SEARCHING FOR A SOLUTION - 16 24 WHERE IS LEGAL? - 32 PSYCHEDELIC PRIMER WATERPROOF HEMP SHOES HIT THE MARKET - 37 WOMAN IN WEED - CHRISTA LENTZ - 41 54 ONIT TESTIMONIAL - 48 BUSINESS OF PSYCHEDELICS BE BETTER WITH GREEN STRATEGIES - 52 NEWS YOU MAY HAVE MISSED - 54 56 IBOGA DEEP DIVE KATSKANNABIS REVIEWS - 60 MISS LINOTTE’S RECIPIES - 63 MERRY MABON - 68 62 HISTORY OF PSYCHEDELICS CLASSIFIEDS - 70 65 CONTENTS MYSTIC MEETS SCIENCE PPPSSSYYYCCCHHHEEEDDDEEELLLIIICCC CCCAAANNNAAADDDAAA MMMAAAGGGAAAZZZIIINNNEEE MARCH 2021 - ISSUE # 1 Psychedelic Canada Magazine is not responsible for the actions, services or quality of the products and services advertised within. We will not knowingly support hate or unethical practices of any advertiser or contributor. Psychedelic Canada Magazine does not support the illigal use of any of the products and services mentioned within these pages - no maer how eye opening orlife changing they may be. Psychedelic Canada Magazine assumes no responsibility for any claims or representations contained within this publication. All material presented is intended for an adult only audience and is intended for entertainment purposes only unless of course you find it informational or educational. All rights reserved. Psychedelic Canada Magazine is owned and operated by High! Canada. Psychedelic Canada Magazine is printed and produced in Canada. For more information on the High Canada Magazine, High! Europe Magazine or Psychedelic Canada Magazine media groups please email [email protected] or visit us online at www.highcanada.net.

Psychedelic Canada Magazine is distributed digitally and by subscription. Psychedelic Canada Magazine is intended to inform and educate adults over 21 about the complexities surrounding psychedelic culture, business, treatment, research. consumption, production and manufacturing. EDITORIAL - Cy Williams -

I have a deep and personal connection with the world around me and it has taken decades of work and education to get me to this point in my life.

To get me to this unique starting point, from which I can truly begin to appreciate and explore my place in and connection to the universe around me.

I will move forward from this starting point by exploring the unique world of psychedelics in Canada within the pages of this new publication Psychedelic Canada Magazine.

I a m a l o n g t i m e a d v o c a t e o f psychedelics, a champion of medicine, an advocate of cannabis and most of all, I believe people should be allowed every opportunity to live their best life.

This magazine represents an unique opportunity to learn about all the different types of psychedelics that exist out there, to check into the psychedelic research being done in Canada and abroad, to highlight the people and companies who are actively working to change the world using psychedelics and to highlight how psychedelics are going to disrupt the billion-dollar industry that is health and wellness www.psychedelicexperience.net/story I invite you to join us in our ongoing exploration of psychedelics in Canada.

This issue I would like to share with you one of my personal favorite psychedelic- based activities which is microdosing and chakra clearing.

This is an exercise I use to clear my chakras and brighten my aura. There are many ways to reflect on the deeper flow of energy that is running through all of us at all times and for me,

I find that microdosing psilocybin and this chakra clearing exercise helps me to remain centered. I encourage you to give it a try.

It is important to open all our chakras and create an even and connected flow Pay aention to thoughts that come up and throughout the whole body. discard ones that are no longer necessary. Put the rest away for reflection for later on. With that said, let me walk you through an exercise intended to both clear your Now move the water down through your chakras and brighten your aura. throat, neck, and shoulders. This is the fifth chakra area. Find a place to sit comfortably with your spine relatively straight. Let the water become warm to ease tense muscles. Feel your neck and shoulders Imagine a clear sparkling stream of water relaxed. You may notice feelings you're a flooding into your head through an holding on to that want to be expressed. opening in your crown chakra, at the top of your head, where the spirit and mind This is the chakra of communications. How meet. open you are determines how well you listen to and communicate with others. Let the water fill your head, is your 6th chakra, of your third eye or intuition. The The water is washing the way all the things cool water is washing away all access you wish you had said or hadn't said and mental activity. all the tension such wishing creates. Continue the stream into your chest, the heart chakra, and wash away all sadness and heaviness of heart. Protective sheets around our hearts. Fill that area with sparkling radiance that opens your heart to give and receive all the love that is available.

The third chakra is the solar plexus area of the body, right below the heart. personal power, reflecting the way you present yourself to the world. Wash it out, clear away any images that keep you from openly experiencing and expressing the full radiant person you are.

Draw the flow deep into your belly, below the navel, your second chakra, the area of emotions especially related to your sexuality. This area is blocked in many of us, so really take that stream and swish it around. Feel yourself being drained of all unnecessary sludge, until your energy is flowing freely.

Now to the final chakra, the first, right at the tip of our spine, our connection to the Earth, our roots, our source of security. Let the stream swirl around the pelvis opening, expanding all the while.

Wash the stream straight down to the tip of the spine and right on down, out the tips of your toes. With each deep breath release all tension and drain off all extra weight.

Feel your energy flowing free and easy all through your body. PPSSYYCCHHEEDDEELLIICC CCAANNAADDAA MMAAGGAAZZIINNEE

Now it's time for real celebration.

Transform the water into golden Light.

Fill your being with this radiance.

When you inhale, run the ray up from the tip of your toes to the top of your head, connecting all chakras, creating PPPSSSYYYCCCHHHEEEDDDEEELLLIIICCC CCCAAANNNAAADDDAAA an even flow between them all.

With the exhale, continue the flow of gold light, out the top of your head, to MMMAAAGGGAAAZZZIIINNNEEE spray down around your body like an exquisite fountain of healing light.

Fill your aura with this healing energy and continue drawing it up through your toes and out again.

Continue practicing this technique as this is truly transforming energy.

It is a wonderful way to start your day or to prepare for a restful sleep with.

I hope you enjoy this inaugural issue!

Cy Williams Publisher/Editor - Psychedelic Canada Magazine email - [email protected] www.instagram.com/thinkmushrooms www.thinkmushrooms.ca [email protected]

www.visualcapitalist.com

PSYCHEDELIC PRIMER

Fueled by a slew of new research, psychedelics may hold the key to treating a multitude of debilitating disorders such as addiction, PTSD, and depression. But as an industry that has stayed hidden in the shadows for decades, it will now need to shed the stigma and legality surrounding it - which have limited its potential and undermined new discoveries for so long.

The infographic above showcases data from The Report on Psychedelics which explains seven of the most common psychedelic substances and examines the many mind-bending ways they could radically transform mental health as we know it. Although evidence of humans using psychedelics as medicine dates back thousands of years, it was not until the 1940s that psychiatrists became advocates of their therapeutic potential. Recreational psychedelics became a symbol of the 1960’s counterculture movement, which added considerable stigma to the industry’s reputation. The U.S. responded by introducing the Controlled Substances Analogue Enforcement Act, deeming these drugs illegal and stymying research studies in the process.

Following some new discoveries in the early ‘90s however, psychedelics moved from the hands of festival- goers back to the labs of scientists. Since then, certain substances such as psilocybin have been granted breakthrough therapy status for treating depression by the U.S. FDA. With these recent developments, new companies and investment opportunities are beginning to emerge in the psychedelics space. But these complex drugs are not always easy to understand—so let’s dive in. WHAT ARE PSYCHEDELICS?

Psychedelics are psychoactive substances that can alter perception, mood, and cognitive processes. There are two broad classifications of psychedelics that relate to chemical structure.

Entheogenic : Plants or fungi that produce chemical substances that can cause hallucinations Synthetic Drugs: Drugs created in laboratory seing to mimic the effects of entheogenic plants

HERE ARE SEVEN OF THE MOST COMMON PSYCHEDELIC SUBSTANCES: PSILOCYBENPSILOCYBEN LSDLSD DMTDMT KETAMINEKETAMINE IBOGAINEIBOGAINE MDMAMDMA AYAHUASCAAYAHUASCA ENTHEOGENIC PLANT PSILOCYBIN Psilocybin is the main ingredient found in several types of psychoactive mushrooms, making it perhaps the best-known naturally- occurring .

Although psilocybin is considered active at doses around 3-4 mg, a common dose used in clinical research seings ranges from 14-30 mg. Its effects on the brain are aributed to its active metabolite, .

Psilocybin is most commonly found in wild or homegrown mushrooms and sold either fresh or dried. The most popular species of psilocybin mushrooms is , which is usually taken orally either by eating dried caps and stems or steeped in hot water and drunk as a tea, with a common dose around 1-2.5 grams.

There are over 180 types of magic mushrooms all with different potency levels (some 12x more than others) in different habitats throughout the world.

They all have different levels of active ingredients which include psilocybin, psilocin and . It is important to understand the levels in the mushroom that you choose to consume because some mushrooms can be 12x more potent than others.

Psilocin is the psychoactive metabolite of psilocybin and baeocystin is a psilocybin derivative or analog.

When psilocybin is eaten it is converted to psilocin which is what causes the psychedelic effect. Baeocystin acts similar to psilocin.

www.dancesafe.org PSYCHEDELIC CANADA MAGAZINE

We need to consider all 3 because when you add One of the biggest telling points of whether a them all up that will give you the total psychedelic mushroom contains psilcoybin or not is if it bruises a potency level of that mushroom. bluish color caused by psilocin activity within it.

There are more than 180 species of hallucinogenic If it bruises blue to almost black in color and has a mushrooms in the world with new species being spore print that is between a purple-brown to rusty- discovered all the time. brown color then you can be almost certain that you have found a . ENTHEOGENIC PLANT HISTORY OF PSILOCYBIN Psychoactive mushrooms have been used for thousands of years and have a long history of both medicinal and ceremonial use among indigenous peoples in many parts of the world, including Europe and the Americas.

They were re-popularized in 1957, when a photo essay featuring an American banker and mushroom enthusiast R. Gordon Wasson was published in LIFE Magazine. Four years earlier, Wasson had stumbled across an indigenous tribe using psychoactive mushrooms in while on vacation and brought back a sample that he then sent to the Swiss chemist known for discovering LSD, Albert Hofmann. Hofmann isolated psilocybin and developed a synthesis f o r t h e d r u g i n h i s l a b a t S a n d o z Pharmaceuticals, which then started producing 2 mg pills to be distributed for research purposes.

For the next two decades thousands of doses of psilocybin were administered in clinical experiments. Psychiatrists, scientists and mental health professionals considered psychedelics like psilocybin to be promising treatments as an aid to therapy for a broad range of psychiatric diagnoses, including alcoholism, schizophrenia, autism spectrum disorders, obsessive- compulsive disorder, and depression. Many more people were also introduced to psilocybin mushrooms and other psychedelics as part of various religious or spiritual practices, for mental and emotional exploration, or to enhance wellness and creativity.

Despite this long history and ongoing research into its therapeutic and medical benefits, psilocybin and psilocin have been listed in Schedule I of the Controlled Substances Act since 1970. This is the most heavily criminalized category for drugs considered to have a “high www.dancesafe.org PSILOCYBIN FOR BEGINNERS

Psilocyben or as it is also called ‘Magic The first thing to consider is our own body, since m u s h r o o m s ’ c a n p r o v i d e y o u w i t h a n the same amount of substance can cause different unforgeable experience, for beer or for worse. effects under different circumstances. Psilocybin, That’s why it’s so important to be as informed as like other , multiplies your mood, so if possible, to prepare the environment, the you are well they will take you to a beer state, but company, and ways to get out of a possible bad if you have a problem they will surely intensify it trip. For these reasons we decided to write this with the intake of mushrooms. post, as a guide for users who want to enter the hidden world of ‘magic mushrooms’. Another important issue is the variety of magic mushrooms, there are many different strains and THINGS TO CONSIDER BEFORE YOU START. each one causes a different effect. The Hawaiian is much more powerful than the Mexican, so taking First of all, it must be said that these are the same amount the effects can be much more entheogenic drugs, and there are people who intense. It is also important to know that should not take any of them. These substances can mushrooms are not the same as magic truffles, so it be the trigger that leads to a psychiatric illness, if is very important to be well informed about each of you are a healthy person you will not have them. problems, but if you have the slightest doubt of being pre-psychotic do not take magic mushrooms Proper preparation of the environment is crucial to under any circumstances. enjoying the trip to the fullest, an environment that is familiar to you makes the experience more The ideal way is to eat them on an empty stomach, comfortable, because when you are under the or at least leave a time of 6 hours from the last influence of Psilocybin you can rediscover reality. ingestion to the intake of truffles or magic It can be at home or outdoors, but try to keep under mushrooms. When you eat them, you can mix them control any possible stimulation that might affect with chocolate, yogurt or other products, since they the quality of the trip. do not have a very pleasant taste. It is important not to overdose, when you are inexperienced it is beer Another key factor is who is with you, we to not get there than to exceed. recommend that it should be trustworthy, people you are safe with and can be yourself. It is Don’t mix mushrooms with other substances, interesting that someone does not use mushrooms cannabis connects very well with psilocybin, but if or other substances and can act as a “keeper” if you are a beginner it is beer not to mix them, so necessary. you can discover the real effect of the magic mushrooms. Without a doubt, the ideal variety to start with Psilocybin is Mexicana, a classic among the entheogenic mushrooms. Mexicana magic truffles HOW MANY MAGIC MUSHROOMS provoke a very pleasant, motivating feeling of ARE SUITABLE FOR BEGINNERS? intoxication, with a certain euphoria and well- being. The visual effects are distortions of the This is the most delicate part, since each body is brightest and most striking shapes and colors, unique and the same dose of the same variety can hardly anything else, no strong hallucinations, so result in different experiences taken by different they do not usually give problems of bad trip. people. You must take into account the person’s Psilocybe Pajaritos are quite similar to the body weight, tolerance to entheogens, medical Mexicana ones, although a lile more powerful on history and metabolism, so it is quite complicated a visual level. They produce a very creative effect, to predict the effects only with the dose. which invites socializing and laughing non-stop when consumed with the right company. On the The threshold dose for magic mushrooms is other hand, when they are taken alone, their effect between 0.009 and 0.035 oz. (0.25-1 gr.), depending is more philosophical and introspective, but with on the variety. The minimum amount of substance few hallucinations if they are not taken in large that must be ingested to feel its effects is called doses. threshold dose. Obviously it is not the same for fresh or dried mushrooms or truffles, we always Another good variety of magic mushrooms for talk about dry weight. b e g i n n e r s i s Ta m p a n e n s i s , k n o w n a s “Philosopher’s Stone“. The effect of this strain is A way to estimate the dose of hallucinogenic very introspective, deep thinking, revealing and mushrooms is by multiplying your body weight X inspiring. Its visual power is in the average, 0.03. For example, for a person weighing 80 kilos it stronger than the Mexicana ones, but without would be 80 X 0.03 = 2.4 grams for a medium power being overwhelming. trip, which for beginners may be too high. As a guideline, it can be said that for Mexicana variety a dose for beginners would be 1.5 grams. IN CASE OF A BAD TRIP OF MAGIC With that amount the trip is usually happy and very bearable, the best way to know that new MUSHROOMS? dimension. The role of the keeper or the person that we advise With Pajaritos variety the dose for beginners can not to consume in each session takes on special also be 1.5 grams, but in this case the trip will have importance here. This person has to check if any an added visual component, also bearable but more psychonauts are having a bad time during the trip intense. and guide or reassure them so they don’t go any further. If it does not improve, ideally he/she If you are going to start with Tampanensis I should eat something sweet or take one of the recommend you to take a lower dose, 1 gram or 1.2 commercial products that help to stop the trip. grams at the most if you are a beginner. The effect of these mushrooms is not super powerful, but if you Magic mushrooms can change your life, but you don’t know them you can get pissed off, and it’s not have to know how to make good use of them. The ideal on a first trip. ideal option is to choose the right time, place and company, and from there let yourself go with the flow as if it were a film, without trying to control H O W L O N G D O E S M A G I C the trip. And the most important thing is that you always come back, don’t think that the effect can MUSHROOM’S TRIP USUALLY bring you problems because thinking that is what LAST? usually brings them, just enjoy the trip.

The duration of the trip can be up to 6 hours in some cases, but as a rule it takes about half an hour to go up, then the effect is maintained for about 2 hours, a n d t h e n i t s t a r t s t o decrease, with a descent that can t a k e a n o t h e r h o u r , s o i t usually takes no m o r e t h a n 4 hours, and in some cases less. www.ncbi.nih.gov/pmc/articles/pmc5367557/ www.ncbi.nlm.nih.gov/pubmed/29119217 www.ncbi.nlm.nih.gov/pubmed/27441452 www.time.com/5278036/michael-pollan-psychedelic-drugs/ www.ncbi.nlm.nih.gov/pmc/pcm3308357/ www.pevgrow.com/en/ www.pnas.org/content/109/6/2138.full www.facebook.com/pevgrow www.twitter.com/pevgrow www.instagram.com/pevgrow ENTHEOGENIC PLANT

Generally, the effects of inhaled, snorted, or injected DMT DMT last for about 30 to 45 minutes. Drinking it in a tea like can leave you tripping for anywhere from 2 to 6 hours.

DMT is a powerful substance that can cause a number of mental and physical side effects. Some of these are desirable, but others not so much.

Possible mental effects of DMT include: Ÿ DMT is a drug that naturally occurs in many plants euphoria Ÿ and animals. It has been called the spirit molecule floating Ÿ because of the psychedelic experience that results vivid hallucinations Ÿ from using it. It is much lesser known than other altered sense of time Ÿ drugs of this nature. depersonalization

People are generally more familiar with magic Keep in mind that some people experience mushrooms or LSD. However, because of its lingering mental effects for days or weeks after use. intensity, it is growing in popularity.a tea, with a common dose around 1-2.5 grams. Physical effects of DMT can include: Ÿ Some experts believe the pineal gland produces it rapid heart rate Ÿ in the brain and releases it when we dream. increased blood pressure Ÿ visual disturbances Ÿ Others believe it’s released during birth and death. dizziness Ÿ Some go further to say this release of DMT at death dilated pupils Ÿ may be responsible for those mystical near-death agitation Ÿ experiences you sometimes hear about. paranoia Ÿ rapid rhythmic eye movements Ÿ Some experts believe the pineal gland produces it chest pain or tightness Ÿ in the brain and releases it when we dream. diarrhea Ÿ nausea or vomiting Others believe it’s released during birth and death. Some go further to say this release of DMT at death may be responsible for those mystical near-death experiences you sometimes hear about. The intensity and duration of a DMT trip depends on several things, including:

Ÿ how much you use Ÿ how you use it Ÿ whether you’ve eaten Ÿ whether you’ve taken other drugs PROPER METHODS OF ADMINISTERING N,N-DIMETHYLTRYPTAMINE

PSYCHEDELIC CANADA MAGAZINE converted to a liquid for distribution. It is odorless, SYNTHETIC DRUG colorless, and has a slightly bier taste. Known as “acid” and by many other names, LSD is sold on the street in small tablets (“microdots”), capsules or LSD gelatin squares (“window panes”). It is sometimes added to absorbent paper, which is then divided into small squares decorated with designs or cartoon LSD is one of the most potent, mood-changing characters. Occasionally it is sold in liquid form. chemicals. It is manufactured from lysergic acid, which is found in the ergot fungus that grows on rye No maer what form it comes in, LSD leads the user to and other grains. the same place—a major disconnection from reality.

It is produced in crystal form in illegal laboratories, LSD users call an LSD experience a “trip,” typically mainly in the . These crystals are lasting twelve hours or so.

Your Brain on LSD

Scientists in the 50’s As recreational use boomed and 60’s used the drug soon most countries to investigate treatments WERE PUSHING for mental illnesses and TO CRIMINALIZE basic neuroscience THE DRUG purposes

For the first time scientists have visualized the effects of LSD on the human brain Brain scans of volunteers on LSD reveal how it alters our brain’s biology

LSD allowed volunteers to see inside their imagination WITH THEIR EYES SHUT

Viisuall corrttex iis much MORE ACTIIVE wiitth tthe rrestt off tthe brraiin

Results show that increased blood flow dirrectly Researchers believe that this connection causes correlates with complex hallucinations and ‘ego-dissolution” or a shift of consciousness an altered state of consciousness from the self towards th surrounding universe

SCIENTISTS HAVE WAITED 5 0 Y E A R S TO SEE HOW LSD IS ACTUALLY ALTERING OUR BRAIN’S BIOLOGY SCIENTISTS HAVE WAITED 5 0 Y E A R S TO SEE HOW LSD IS ACTUALLY ALTERING OUR BRAIN’S BIOLOGY

MUSIC COUPLED WITH LSD may be a powerful therapeutic combination

Studies show that listening to music while taking LSD stimulated brain areas involved in mental imagery People reported seeing COMPLEX EYES-CLOSED VISIONS and scenes from their lives www.geoffreygnathanlaw.com ENTHEOGENIC PLANT AYAHUASCA

Ayahuasca is an herbal drink made from plants that grow in the Amazon jungle. For centuries, this tea has The ayahuasca tea is used to bring on a "mental been used in healing ceremonies. The drink causes awakening." In a 2014 article for Live Science, hallucinations and is said to have spiritual and contributor Benjamin Radford cited a passage from therapeutic benefits. In recent years, it has aracted the book "Magic and Witchcraft: From to the aention of Western medicine as a possible the Technopagans" (Thames and Hudson, 2003). treatment for depression. The drug has also become Author Nevill Drury, an anthropologist, wrote, "… in popular with people seeking a "shaman experience." the upper Amazon basin (Colombia, Peru and According to the journal Nature, a booming industry Ecuador) shamans make extensive use of ayahuasca. has developed in South America, as thousands of … Taking this sacrament allows the shaman to enter people pay big money to aend retreats so they can the supernatural realm, to have initiatory visions, and sample ayahuasca's "intense psychedelic insights." to make contact with ancestors and helper-spirits." However, the drink has also been linked to several deaths among "ayahuasca tourists." Writer William Burroughs wrote about drinking ayahuasca in his book, "The Yage Leers," in which he People must travel to take part in an ayahuasca wrote to poet Allen Ginsberg of his experiences. ceremony because the drink is illegal in the United Burroughs wrote that he at first thought he had been States. Some believe that while they are high on poisoned, and that he felt himself turning into a half- ayahuasca they gain a beer sense of self or are beer man-half-woman. He praised the tea for its ability to equipped to work through mental trauma, leading to facilitate "space time travel," according to an article in beer mental health after the session. Scientific American.

The recipe for ayahuasca — also spelled iowaska or While Western medicine has known about ayahuasca hoasca, and also called daime, yajé, yagé, natema for around 100 years, lile is known about how it and vegetal — differs by region, according to a 2003 works, according to an article in the Journal of paper in the Journal of Pharmacology. In Brazil, Peru Ethnopharmacology. While there is a lot of anecdotal and Ecuador pounded stems of a flowering vine evidence that ayahuasca can help with depression and (Banisteriopsis caapi) are used to make the teas, mental trauma, most studies on the subject have been either alone or combined with the leaves of a pilot studies or used very few test subjects. (Psychotria viridis). In Ecuador and Colombia, the stems of B. caapi are combined with a different shrub The physical effects of drinking ayahuasca include (Diplopterys cabrerana). vomiting, diarrhea, elevated blood pressure, elevated heart rate, higher rectal temperature and dilation of The tea is prepared by an ayahuasquero, who is the pupils. It can also elevate blood concentrations of typically trained in the traditional ways of preparing naturally occurring pain relievers, such as beta- the tea. The ayahuasquero prepares and serves the tea endorphin, corticotropin, cortisol and prolactin, and during a ceremony that usually takes place in a also increase growth hormone levels, according to a shaman's hut. Those partaking in the tea lie on grass study by the University of New Mexico. In this study, mats or maresses while riding out the high, which researchers found that DMT can be administered can last for hours. safely to experienced users.

www.soul-herbs.com

THE DARK SIDE OF AYAHUASCA In 2012, Kyle Nolan, a California teenager, disappeared during a retreat to a Peruvian There is a dark side of drinking ayahuasca. Though not shamanic center. A shaman later confessed that common, some "ayahuasca tourists" have died, and Nolan died from exceeding the dosage of many Westerners have reported being molested and ayahuasca, and that he had buried Nolan's body in raped, according to an article in Men's Journal. The the jungle, according to the Daily Mail. tourist boom has given rise to charlatans and fake shamans. Extreme caution is advised while planning a psychelic adventure. In 2014, Henry Miller, a British backpacker traveling in Colombia, died after a "shaman A French woman died in 2011 after drinking ayahuasca, experience." His death apparently was caused by an but it was reported that she had a pre-existing heart allergic reaction to the drink. He became sick condition. Another Frenchman died a few months later, during the event and was left to die by the side of a probably due to interactions with other . dirt road, according to the Guardian. SYNTHETIC DRUG

If you’ve heard of , it’s probably for KETAMINE its history of abuse as a club drug. But it c o u l d a l s o b e o n e o f t h e b i g g e s t breakthroughs in treating severe depression in years. How can one drug hold such promise and peril? The answer lies in how it affects your brain.

Ketamine works like a flash mob, temporarily taking over a certain chemical “receptor.” In some cases and with expert medical care, that can be a good thing. But cross that line, and it’s big trouble. Your doctor probably won’t give it to you as an antidepressant yet. Scientists are still testing it for that. But if ketamine does bring people back from the depths of depression, it might be the last thing you expect from a drug that can knock you out.

Ketamine got its start as an anesthesia medicine in the 1960s. It was used on the balefields of the Vietnam War. At lower doses, it can help ease pain. Ketamine helps sedatives work and may help people need fewer addictive painkillers, like after surgery or while caring for burns. Continued

When misused, ketamine can change your sense of sight and sound. You can have hallucinations and feel out of touch with your surroundings -- and even from yourself. It can make it hard to speak or move, and it has been abused as a date-rape drug.

“Outside of the clinic, ketamine can cause tragedies, but in the right hands, it is a miracle,” says John Abenstein, MD, president of the American Society of Anesthesiologists. www.instagram.com/royal_oil_rub SYNTHETIC DRUG

orally, whether in pressed pill form, powder or MDMA crystal; or sometimes snorted.

MDMA was originally synthesized in 1912 by the MDMA, often referred to as “ecstasy” or “molly”, drug company Merck.1 However, its psychoactive is short for 3,4 methylenedioxymethamphetamine, effects weren’t widely discovered until 1976 when a derived from safrole oil. Alexander Shulgin developed a new synthesis MDMA produces effects that resemble both method, tested the drug on himself, and shared it stimulants and psychedelics, as well as its with a few friendly psychotherapists.2 Because of signature effect: a feeling of connectedness. It the drug’s effects of increasing empathy and impacts brain function primarily releasing the reducing fear, it started to be used in neurotransmier serotonin, and also temporarily psychotherapy practices in the 1970s and early 80s, inhibits its reuptake. MDMA is usually taken as well as recreationally.

www.addictionblog.org ENTHEOGENIC PLANT IBOGAINE

Ibogaine is a naturally occurring psychedelic substance found in iboga, a Western African shrub. Historically it has been used in healing ceremonies and initiation rituals in the religion in .

It is a psychedelic with properties. Preliminary research indicates that it may help counter drug addiction. While the drug can lead to some short-term side effects, including anxiety after experiencing hallucinations, it has been touted for a few years as a potential solution to devastating addiction problems.

Recently, more studies in the Western world have focused on ibogaine as a potential treatment for addiction, especially to , methamphetamine, and even cocaine, which are some of the most addictive substances.

Anecdotal evidence suggests that ibogaine, which is derived from a plant found in the African , adjusts brain chemistry to the point that a person who otherwise might experience intense withdrawal symptoms for one or two weeks does not go through withdrawal or suffer from cravings.

However, scientists exploring the potential of this drug in addiction treatment do not believe ibogaine completely ends addiction; instead, it interrupts the process. Addressing the Universal Desire to Heal.

4,000 The number of Canadians who die by suicide per year – almost 11 suicides per day #4 Canada’s rank in the use of a ndepressant drugs per capita. The use of andepressants is 50% on the rise globally. Percentage of Canadians experiencing a major depressive episode that do not receive 500,000 “potenally adequate care” Number of unemployed Canadians who are unable to work due to 9%+ mental health problems Percentage of Canadian 1 in 2 adults who will suffer PTSD The number of Canadians In their lifeme who will be affected by mental health issues $51B by the age of 40 Esmated annual economic burden of mental illness in Canada 1 in 5 The number of Canadians who suffer from addicon Transformave change is needed in any given year www.internationalcbc.com ayton Nyquvest stands behind the belief that Pthe societal costs of mental illness, addicons, trauma, and unmet human potenal are much too high. He is the CEO and Founder of Numinus Health & Human Advancement who have been licensed by Health Canada to p r o d u c e a n d e x t r a c t psilocybin from mushrooms. Numinus is at the forefront of addressing the growing prevalence of mental health issues and desire for overall greater wellness.

One in five Canadians suffer from addicon in any given year, and deaths from the current overdose crisis aributable to and other addicons are growing. Companies of note Numinus a n d To g e t h e r We C a n Addicon Recovery and Educaon Society (TWC) share the view that new B U S I N E S S O F P S Y C H E D E L I C S soluons and integrave approaches are needed to S P O T L I G H T O N enhance tradional recovery- based approaches to help C E O & F O U N D E R A T people make transformave change, heal, and be well. NUMINUS | HEALTH & HUMAN ADVANCEMENT The partnership announced t h i s s u m m e r c u r re nt l y PAYTON NYQUVEST extends the connuum of care provided lower costs to currently produced to TWC clients with specialized synthec psilocybin. The licence also mind/body programs which include allows Numinus to develop and licence its modalies such as , own exclusive IP for further product registered massage therapy, trauma and development in partnership with leading somac therapies, and breathwork research organizaons — something the through Numinus's associated wellness research community has been seeking to clinic in Vancouver. Individualized secure. programs are connually being developed for Together We Can The company’s exisng licence (in Addicon Recovery and Educaon alignment with licence holder Salvaon Society clients, including Canadian Botanicals Ltd) allows Numinus to test, Forces members and veterans dealing possess, buy and sell MDMA, psilocybin, with addicon, PTSD, anxiety, grief and psilocin, DMT, and . loss, and other diagnoses. Numinus is dedicated to providing access Numinus has received Health Canada to t h e ra p i e s t h at e n h a n c e a n d approval to amend the Company’s s u p p l e m e n t e x i s n g o p o n s . exisng licence under the Controlled Psychedelics will be part of this but will Drug and Substances Act to allow only be available for treatment once Numinus researchers to conduct approved by regulators and governing research to standardize the extracon of bodies. psilocybin from mushrooms. The amendment means Numinus is the first Payton and Numinus are publicly traded company in Canada to be granted a licence by Health Canada to addressing conduct research of this kind.

With this regulatory approval, Numinus the universal is able to proceed with the producon of desire to heal naturally sourced, sustainable psilocybin and in doing so are opening for research purposes that will support the emerging field of psychedelic- up countless new roads for assisted psychotherapy and research, at healing. PSYCHEDELIC CANADA MAGAZINE

IBOGA DEEP DIVE

bogaine is a crystalline d o g b a n e f a m i l y A n e v e r g r e e n b u s h hallucinogen () that is indigenous to , the IC20H26N2O obtained found in equatorial Africa. Democrac Republic of from the roots, bark, and iboga is a Congo, and the Republic of leaves of the Tabernanthe perennial rainforest shrub Congo, it is culvated i b o g a p l a n t o f t h e nave to West Africa. a c r o s s We s t A f r i c a . WHERE IS IBOGAINE LEGAL?

If you are searching for an Ÿ Australia. In 2010, Ibogaine was scheduled as a Schedule 4 Ibogaine therapy centre, be substance on Australia’s Poisons List. It remains a Schedule 4 selecve. A high-quality substance pursuant to the February 2019 Poisons Standard, ibogaine treatment centre which means it is a Prescripon Only Medicine. priorizes safety, pracces under medical supervision, Ÿ Brazil. Ibogaine is legal to possess and distribute in Brazil. In and follows clinical guidelines. Sao Paolo, Brazil’s capital city, Ibogaine must be administered Ÿ in a medical environment where Ÿ . Ibogaine has been adequate paent protecons are in place. medicalized in New Zealand and can On January 24, 2016, the President of the be obtained with a prescripon and Naonal Associaon of the Study of Drug taken under medical supervision. As a Policy (CONED-SP) in Sao Paolo issued a result, you can go to an Ibogaine declaraon calling for the scienfic study treatment centre in New Zealand that of psychoacve substances, and offers an Ibogaine prescripon under approving the medical use of ibogaine “in the super vision of a medical a hospital environment, with medical p r o f e s s i o n a l . supervision and control, meeng the exercise of the profession and the Ÿ . The South African recommendaons of good clinical government has licensure procedure pracce, including rigorous clinical and in place for those who want to provide p s y c h i a t r i c e x a m i n a o n s a n d m e d i ca l I b o ga i n e t re at m e nt . p s y c h o l o g i c a l a s s e s s m e n t a n d psychotherapeuc monitoring.” Ibogaine is illegal in the Ÿ Costa Rica. In Costa Rica, Ibogaine was fo l l o w i n g c o u nt r i e s : legal for some me, but it is no longer l e g a l a s o f 2 0 1 8 . Costa Rica Ÿ Gabon. Gabon lies on the west coast of central Africa. The naonal law of Gabon p r o t e c t s i b o g a p l a n t s . Hungary Ireland Ÿ Guatemala. It is legal to treat with Italy Ibogaine in Guatemala. An Ibogaine Norway treatment centre is located in Angua, which is located near Guatemala City. England Ÿ Mexico. Ibogaine is legal but unregulated The United States in Mexico. Therefore, Mexico is a popular s p o t f o r i b o g a i n e t r e a t m e n t . Ibogaine is not a scheduled substance and it’s status for Ÿ . The Netherlands does not medical use to interrupt drug prohibit Ibogaine, and there are various dependence disorders remains in ibogaine treatment centres available. queson in Canada, and Israel. S i n c e I b o g a i n e w a s a dream-like state while on , it also took introduced to the western awake, as well as closed away his craving to use, all world as an addicon eye imagery and the w i t h n o w i t h d r a w a l interrupter it has been retrieval of repressed symptoms. Lots of spent slow to gain approval as a memories. t h e r e s t o f h i s l i f e prescripon medicine for a d v o c a n g f o r t h e various reasons, despite Its physical effects can development of Ibogaine the success of the early include ataxia, nausea and as a prescripon medicine. phases of clinical trials and voming, sensivity to c o n n u e d r e s e a r c h . light and sound, tremors, In the early 1990’s, the US and cardiac effects. In the Naonal Instute on Drug Ibogaine is a naturally early 1960’s, the Chilean Abuse (NIDA) began the occurring psychoacve psychologist Claudio development of Ibogaine substance that has been Naranjo conducted 40 by fully funding pre-clinical demonstrated to interrupt Ibogaine sessions with his animal trials as well as substance use disorders, clients and was the first to Phase 1 safety trials on as well as possess other scienfically describe the human subjects under the n e u r o l o g i c a l a n d experience. He reported auspices of Dr. Deborah psychological benefits. It is that Ibogaine helped Mash at the University of found naturally and has people to view difficult M i a m i . T h e r e s u l t s been used for centuries by e x p e r i e n c e s i n a n confirmed that Ibogaine tradional communies in objecve way, and that it d e c r e a s e s t h e s e l f - West Africa for ritual and helped to facilitate closure a d m i n i s t r a o n o f h e a l i n g p u r p o s e s . of unresolved emoonal smulants, and conflicts. , as well as a In lower doses, Ibogaine significant reducon in the a c t s a s a s m u l a n t , The occidental use of withdrawal symptoms increasing energy and Ibogaine, especially its from opiates. ((Popik P, decreasing fague in a way a p p l i c a o n i n t h e G l i c k S . I b o ga i n e , a that is disnct from other treatment of substance putavely an-addicve central nervous system u s e d i s o r d e r s , w a s alkaloid. Drugs of the s m u l a n t s l i k e pioneered by Howard Lots. Future. 1996; 21:pp 1109- a m p h e t a m i n e s a n d In 1962, 19 year old Lots 1115.)) cocaine. In larger doses, found that a single dose of I b o g a i n e p r o d u c e s I b o g a i n e n o t o n l y U n f o r t u n a t e l y, t h e o n e i r o g e n i c e ffe c t s , i n t e r r u p t e d h i s development research meaning that it smulates physiological dependence was ended prematurely relave to NIDA’s exisng a l c o h o l , e s s e n a l l y c o n d u c t e d b y t h e resources. Phase 1 safety returning the user to a M u l d i s c i p l i n a r y trials conducted by NIDA n o v i c e s t a t e . U s i n g A s s o c i a o n f o r found that Ibogaine is not s u b s t a n c e s a e r P s y c h e d e l i c S t u d i e s neurotoxic. However, administraon of ibogaine (MAPS), aempng to there are a number of without taking this into t ra c k t h e l o n g - t e r m fatalies that have been consideraon presents a efficacy of ibogaine- temporally associated s i g n i fi c a n t r i s k o f assisted detox therapy. with the ingeson of overdose. Ibogaine. These were The studies, in Mexico and aributed to a variety of In the late 1980’s, the first N e w Z e a l a n d , h a v e factors, including pre- regular Ibogaine-assisted reported preliminary e x i s n g m e d i c a l detox sessions were results of between 20% condions, especially conducted by the Danish and 50% rate of clients cardiac condions, as well Drug Users Union in remaining free from their as seizures resulng from Amsterdam. Over the last primary substance of acute withdrawal from several decades a global abuse for at least 12 a l c o h o l o r community of ibogaine m o n t h s . F a c t o r s , and in therapy providers, which influencing this range o t h e r c a s e s t h e c o - h a s b e e n d u b b e d a were suggested to be the administraon of one or “medical subculture,” has ease of follow-up in the more drugs of abuse. developed to include N e w Z e a l a n d s t u d y former drug users and b e c o m e o f c l o s e r One of the causes cited is physicians. In 2007 it was proximity, as well as other that Ibogaine potenates esmated that over 3,400 factors such as plans for the effects of opiates, as therapy sessions for connuing care. well as their lethality if co- substance use disorders, administered. It does this as well as for personal and Ibogaine therapy not by acng as an spiritual growth, had been m a y h a v e agonist or antagonist, but conducted worldwide. promising results in by enhancing opiate the treatment of signalling. Another is that, This number connues to other condions, in addion to aenuang grow annually, as well as including Hepas withdrawal symptoms, the number of clinics. C , P a r k i n s o n ’s ibogaine has been shown Ibogaine-assisted detox d i s e a s e a n d to reduce developed efficacy has been explored T o u r e e ’ s tolerance to opiates and in two recent studies being syndrome. CREDITS:

D.C. Mash, C.A. Kovera, B.E. Buck, Juan Sanchez-Ramos. Medicaon development of ibogaine as a pharmacotherapy for drug dependence. Annals of the New

York Academy of Sciences 844:274-92 · June 1998

“Modificaon of awake-sleep equilibrium by and some of its derivaves in the cat.” Da Costa L, Sulklaper I, Naquet R. Review of

Electroencephalography and Clinical Neurophysiology. 10:105-112. 1980.

Kaplan, C.D., Ketzer, E., de Jong, J. and de Vries, M. Reaching a state of wellness: Mulstage exploraons in social neuroscience. Social Neuroscience Bullen,

1993, 6: 6-7.

Mash DC, Kovera CA, Pablo J, Tyndale RF, Ervin FD, Williams IC, Singleton EG, Mayor M. Ibogaine: complex pharmacokinecs, concerns for safety, and

preliminary efficacy measures. Ann N Y Acad Sci. 2000 Sep;914:394-401.

The Healing Journey. “Ibogaine: Fantasy and Reality.” Claudio Naranjo. New York, 1974. Read full chapter.

Deborah C. Mash, Craig A. Kovera, and John Pablo, Rachel Tyndale, Frank R. Ervin, Jeffrey D. Kamlet, W. Lee Hearn. Ibogaine in the Treatment of Heroin

Withdrawal THE , Vol.56, 2001 Academic Press. ↩

Alper, Kenneth R. M.D., Marina Stajic, Ph.D., and James R. Gill, M.D. Fatalies Temporally Associated with the Ingeson of Ibogaine. Journal of Forensic

Sciences, March 2012, Vol. 57, No. 2.

Trujillo KA & Akil H, Inhibion of Morphine Tolerance and Dependence by NMDA MK-801, Science, 2512:85-87, 1991.

Khanna JM, Kalant H, Shah G, Chau A, Effect of D- on Rapid Tolerance to Ethanol, Pharmacology Biochemistry & Behavior 45(4):983-986, 1993.

Kenneth R. Alper, Howard S. Lotsof, Charles D. Kaplan. The ibogaine medical subculture. Journal of Ethnopharmacology. 115: 9–24. 2007.

hps://www.ibogainealliance.org/ibogaine/ www.visualcapitalist.com www.tryptherapeutics.com www.instagram.com/jacksgaragedoc PSYCHEDELIC CANADA MAGAZINE PSYCHEDELIC CANADA PSYCHEDELIC CANADA MAGAZINE MAGAZINE PSYCHEDELIC CANADA PSYCHEDELIC CANADA MAGAZINE

PSILOCYBIN MUSHROOMS - MYSTIC MEETS SCIENCE

Psilocybin is a naturally occurring advanced ancient civilizations like the Greeks psychoactive compound that is synthesized had Secretive cults who brewed psychedelic by over 200 mushrooms of the Psilocybe teas and used them to induce a boost of (pronounced sil-ohh-si-bee) genus. It’s not creativity and enlightening epiphanies. clear why these mushrooms have evolved to produce a compound that closely imitates a When scientiically rigorous protocols are crucial human neurotransmitter (serotonin). used to study psilocybin the indings are often One theory suggests it is a fungal defence consistent with the teachings of ancient mechanism, as psilocybin also alters the shamans, that the compound can drastically behaviour and appetite of insects, while and sustainably improve many aspects of another postulates that these mushrooms mental health. It has been studied (with were introduced to the earth by alien beings extremely promising results) at numerous to expedite human evolution. Psilocybin prestigious institutions (like Harvard, belongs to a class of drugs often referred to as Stanford, and Yale) to determine its safety and or entheogens, humans use of eficacy in treating debilitation psychological these mind altering substances stretches conditions, including but not limited to back farther than civilization itself! With the addictions, depression, anxiety, and PTSD. earliest evidence found in Northern Spain Researchers at these institutions have delved dating to 11,000 years ago. Tribal peoples all deep into the pharmacology behind Psilocybe around the world from Mesoamerica to mushrooms, inding that various species of the Southeast Asia revered these mushrooms for genus produce differing concentrations of the profound insights and intense feelings of many psychotropic tryptamine compounds, euphoria, love, and connectedness that they the most prevalent of these being psilocybin, felt after ingesting them. However it wasn’t psilocin, and baeocystin. They also found that only tribal hunter gatherers who utilized the compound responsible for producing the psilocybin, Philosophically and scientiically mind-altering effects associated with these PSYCHEDELIC CANADA MAGAZINE PSYCHEDELIC CANADA PSYCHEDELIC CANADA MAGAZINE MAGAZINE PSYCHEDELIC CANADA PSYCHEDELIC CANADA MAGAZINE MAGAZINE mushrooms is not psilocybin, but psilocin. Brain Derived Neutrophic factor is a protein that After you eat ‘magic mushrooms’ psilocybin is helps to stimulate and control the process of dephosphorylated (the removal of a neurogenesis, it also plays a key role in long- phosphorus molecule) by the liver into t e r m m e m o r y, n e u r a l d e v e l o p m e n t , psilocin, whose molecular structure is highly coordination, and the deciphering of sensory similar to that of serotonin, one of the most input by the brain. important neurotransmitters in the human brain. The Default Mode Network is responsible for a variety of cognitive functions including day- Psilocin is so similar to serotonin that it is able dreaming, self-relection, and the ability to to bind with numerous serotonin receptors perceive the past, present, and future. Some (speciically the 5-Hydroxytryptamine studies suggest that depression is linked to an receptor group). When this bond is formed it overactive DMN. The theory behind this is the causes drastic changes in neural chemistry, possibility that a highly active DMN causes us to t r a n s m i s s i o n a n d c r o s s - n e t w o r k extensively ruminate, over-analyze, and become communication, primarily the increased removed from the present moment to question secretion of Glutamate & Brain Derived the past and the future. Neutrophic Factor, dampening of the Default Mode Network, and the re-routing of *visualization of brain connections/activity in information through brain networks that are subjects given placebo (left) and psilocybin not connected in the “sober” state of (right) consciousness. These changes culminate in the stimulation of neurogenesis, synesthesia, As previously stated, it has been known that s e n s o r y e n h a n c e m e n t , a n d v i s u a l ingesting mushrooms produces an enhanced stimulation/hallucination that are associated state of consciousness for many millenia, with magic mushrooms. however it is only recently, and in light of promising research, that the perception by Glutamate is an vital neurotransmitter that authorities and institutions alike has begun to accounts for over 90% of the synaptic shift towards the recognition of medical beneits connections in the brain, and is involved in associated with these drugs. Three major U.S. crucial brain functions like cognition, learning, cities (Denver, Chicago, and Oakland) have memory, and energy acquisition. decriminalized psilocybin, while legislative motions are in progress for over 100 additional Along with exogenous stimulation, your mindset and localities, meanwhile Democratic politicians Andrew intention of what you want to get out of the Yang and Alexandria Ocasio-Cortez have both experience also has the potential to drastically affect declared their support for federal policy reform what you will feel while psilocybin is being around psychedelics. The FDA has also stated “we metabolized. Personally I set intent on becoming have never seen such a powerful drug, requiring such more sociable, overcoming my somewhat introverted infrequent use” and attempted to fast-track it through nature, and always have a pen and paper handy to the clinical trial process by designating it as a transcribe any insights that the mushroom grants. I “breakthrough therapy” for Major Depressive think about what I can do to strengthen both my Disorder (MDD). relationships with others, and my own psyche against negative emotion. Sometimes the result of this This re-invigourization of psychedelic drugs into pondering is challenging, and forces me to step out of public consciousness is also taking place north of the my ‘comfort-zone’, however I feel that the results have American border. Jagmeet Singh (leader of the NDP) been extremely vindicating, and that psychedelics has proposed sweeping changes to Canadian drug have been the catalyst for immense personal growth, scheduling and legality, Vancouver city council making me a more empathetic, generous, self-aware, recently blocked a motion to prevent sales of and relaxed person. psilocybin mushrooms, and Dana Larsen is set to open a micro-dose dispensary storefront in To conclude, similar to consciousness itself, we Vancouver by early February! All of this sentiment understand much of the biological function was catalyzed by only a handful of studies that have underpinning a psychedelic experience (described already been concluded, however there is an above) but seem to lack a crucial component of why it exponentially increasing amount of interest in the is so metaphysical, why it can reliably induce topic, and we can expect many new studies transformative experiences that result in sustained corroborating positive results in the coming years improvement in mood and mental well-being, and how this substance (psilocybin) evolved to interact *Number of studies on psychedelic substances with consciousness in such a profound way. 1960-2016 When one ingests psilocybin, the intense feelings of So far this article has been markedly science focused, connectedness, love, empathy and understanding, however there are aspects of the psychedelic and the realization that these emotions are experience that are not explainable by current antediluvian and transcend our ego’s is so strong that psycho-scientiic knowledge. A few examples of this it can be overwhelming. You are looded with are the crucial importance of set and setting, why emotion, often see geometric patterns or waves, across varied demographics psilocybin reliably consistent with sacred geometry, and are able to induces similar spiritual and transformative clearly and eficiently process thoughts as if from a experiences, even out of body experiences, and the omniscient perspective, while your mind wanders a role that auditory stimulation plays in the experience. vastly expansive and immersive realm that can only Your physical surroundings, for example be accessed through ingesting the wondrous temperature, others around you, the amount of light compound that we call Psilocybin. in your setting, the type of music you play during the experience, and your level of familiarity with these Check out our shop for a variety of dried mushroom variables play a role almost as important as the strains, micro-doses, and ready-to-brew mushroom dosage of the drug itself! Research at Johns Hopkins teas. University recently conirmed that music is inexplicably intertwined with both the psychedelic experience and human neuro-chemical reward systems. They have curated a playlist, noting the tempo and arrangement of tracks, that builds into a crescendo peaking around 2 hours into the playlist (also when the effects of psilocybin peak) in an effort JEFF to assist an individual into having a truly profound experience. WWWCHAMPIGNONMAGIQUE.CA.CHAMPIGNONMAGIQUE.CA

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